Shunya Takahashi

发表

A novel DNA polymerase inhibitor and a potent apoptosis inducer: 2-mono-O-acyl-3-O-(alpha-D-sulfoquinovosyl)-glyceride with stearic acid.

K. Sakaguchi, F. Sugawara, H. Yoshida, 2003, Biochimica et biophysica acta.

Chemical Transformation of a 1-Deoxynojirimycin Derivative into 1-Deoxymannojirimycin and 1-Deoxygalactostatin

Shunya Takahashi, H. Kuzuhara, 1998 .

Title Cytoprotective effects of lysophospholipids from sea cucumberHolothuria atra

Shunya Takahashi, M. Ohnishi, H. Koshino, 2016 .

Cytoprotective Effects of Lysophospholipids from Sea Cucumber Holothuria atra

Shunya Takahashi, M. Ohnishi, H. Koshino, 2015, PloS one.

Ubiquitin-Specific Peptidase 5, a Target Molecule of Vialinin A, Is a Key Molecule of TNF-α Production in RBL-2H3 Cells

S. Yajima, Shunya Takahashi, Yasukiyo Yoshioka, 2013, PloS one.

The effects of dehydroaltenusin, a novel mammalian DNA polymerase alpha inhibitor, on cell proliferation and cell cycle progression.

K. Sakaguchi, F. Sugawara, H. Yoshida, 2004, Biochimica et biophysica acta.

Total Synthesis of the Proposed Structure for Chaunopyran A and Its Absolute Configuration.

Shunya Takahashi, H. Koshino, N. Ogawa, 2020, Journal of natural products.

Design and synthesis of a heparanase inhibitor with pseudodisaccharide structure

Shunya Takahashi, H. Kuzuhara, M. Nakajima, 2001 .

Formal total synthesis of aspergillide A

Shunya Takahashi, H. Koshino, T. Nakata, 2011 .

First total synthesis of theopederin B

Shunya Takahashi, T. Nakata, Y. Nishii, 2009 .

Stereoselective total synthesis of mucocin, an antitumor agent.

Shunya Takahashi, T. Nakata, A. Kubota, 2002, Angewandte Chemie.

Novel catalytic activity of nitrile hydratase from Rhodococcus sp. N771.

M. Maeda, M. Yohda, N. Dohmae, 2008, Journal of bioscience and bioengineering.

Isolation of (E)-9,10-dihydroxy-2-decenoic acid from royal jelly and determination of the absolute configuration by chemical synthesis

Shunya Takahashi, H. Koshino, Yayoi Hongo, 2009 .

Inhibitory effects of vialinin A and its analog on tumor necrosis factor-α release and production from RBL-2H3 cells.

S. Yajima, Shunya Takahashi, Yasukiyo Yoshioka, 2012, Cellular immunology.

Design and synthesis of a vialinin A analog with a potent inhibitory activity of TNF-α production and its transformation into a couple of bioprobes.

Shunya Takahashi, H. Koshino, N. Abe, 2012, Bioorganic & medicinal chemistry letters.

Vialinin A, a novel potent inhibitor of TNF-alpha production from RBL-2H3 cells.

Shunya Takahashi, H. Koshino, N. Abe, 2008, Biological & pharmaceutical bulletin.

Facile Preparation of 1,6-Anhydro-2-azido-3-O-benzyl-2-deoxy-.BETA.-D-glucopyranose and Its 4-O-Substituted Derivatives.

Shunya Takahashi, N. Sakairi, H. Kuzuhara, 1994 .

Total Synthesis of Kehokorins A-E, Cytotoxic p-Terphenyls.

Shunya Takahashi, K. Matsuoka, H. Koshino, 2017, The Journal of organic chemistry.

Kujigamberol, a new dinorlabdane diterpenoid isolated from 85million years old Kuji amber using a biotechnological assay.

Shunya Takahashi, T. Miyakawa, H. Koshino, 2012, Fitoterapia.

Synthesis and biological activity of both enantiomers of kujigamberol isolated from 85-million-years-old Kuji amber.

Shunya Takahashi, D. Hashizume, H. Koshino, 2012, Bioorganic & medicinal chemistry letters.

Inhibitory activity of Brazilian green propolis components and their derivatives on the release of cys-leukotrienes.

Shunya Takahashi, H. Koshino, H. Tani, 2010, Bioorganic & medicinal chemistry.

Pyranicin, a non-classical annonaceous acetogenin, is a potent inhibitor of DNA polymerase, topoisomerase and human cancer cell growth.

H. Yoshida, Y. Mizushina, Shunya Takahashi, 2008, International journal of oncology.

Synthesis and Biological Activity of Both Enantiomers of Kujigamberol Isolated from 85‐Million‐Years‐Old Kuji Amber.

Shunya Takahashi, D. Hashizume, H. Koshino, 2012 .

Anti‐tumor Effect of Chemically Synthesized Sulfolipids Based on Sea Urchin's Natural Sulfonoquinovosylmonoacylglycerols

K. Sakaguchi, F. Sugawara, Y. Mizushina, 2002, Japanese journal of cancer research : Gann.

Total synthesis of (+)-methyl trisporate b, fungal sex hormone

Shunya Takahashi, T. Oritani, K. Yamashita, 1988 .

Enantioselective Synthesis of ( + )-Methyl Trisporate B

Shunya Takahashi, T. Oritani, K. Yamashita, 1987 .

Total synthesis of muconin

Shunya Takahashi, T. Nakata, A. Kubota, 2002 .

Structural determination of montanacin D by total synthesis.

Shunya Takahashi, H. Koshino, Yayoi Hongo, 2008, Organic letters.

Simple syntheses of L-fucopyranose andfucosidase inhibitors utilizing the highly stereoselective methylationof an arabinofuranoside 5-urose derivative

Shunya Takahashi, H. Kuzuhara, 1997 .

Preparation of a Demethylallosamidin Isomer Having an N,N'-Diacetylchitobiosyl Moiety and Its Potent Inhibition against Yeast Chitinase

Shunya Takahashi, S. Sakuda, Yasuhiro Yamada, 1994 .

Total synthesis of (−)-Allosamidin, an insect chitinase inhibitor, employing chitin as a key starting material

Shunya Takahashi, H. Kuzuhara, H. Terayama, 1992 .

Synthetic studies on macroviracin A: a rapid construction of C(42) macrocyclic dilactone corresponding to the core.

Shunya Takahashi, H. Koshino, T. Nakata, 2004, The Journal of organic chemistry.

Determination of absolute structure of macroviracins by chemical synthesis.

Shunya Takahashi, H. Koshino, T. Nakata, 2003, Organic letters.

Total synthesis of curvulone B and a proposed structure for dothiorelone B; determination of the configuration of curvulone B and structural revision of phomopsin A

Shunya Takahashi, H. Koshino, Takemichi Nakamura, 2012 .

Synthesis and structural revision of phomopsin B, a novel polyketide carrying a 10-membered cyclic-ether ring.

Shunya Takahashi, H. Koshino, N. Kanomata, 2011, Organic letters.

Simple and efficient synthesis of highly functionalized cyclohexanes; formal total synthesis of ovalicin and fumagillin

Shunya Takahashi, H. Koshino, Yayoi Hongo, 2011 .

Stereoselective synthesis of (2R,3S,4S)-3-hydroxy-4-methyl-2-tetradecyl-4-butanolide starting from 2,5-anhydro-d-mannitol

Shunya Takahashi, N. Sakairi, T. Nakata, 2005 .

Total synthesis of an anticancer agent, mucocin. 2. A novel approach to a γ-hydroxy butenolide derivative and completion of total synthesis

Shunya Takahashi, T. Nakata, 1999 .

Total synthesis of the proposed structure for pyragonicin.

Shunya Takahashi, H. Koshino, T. Nakata, 2005, Organic letters.

Total synthesis of a cytotoxic acetogenin, pyranicin.

Shunya Takahashi, T. Nakata, A. Kubota, 2003, Organic letters.

Stereoselective total synthesis of muconin

Shunya Takahashi, T. Nakata, A. Kubota, 2003 .

TOTAL SYNTHESIS OF AN ANTICANCER AGENT, MUCOCIN. 1. STEREOSELECTIVE SYNTHESIS OF THE LEFT-HALF SEGMENT

Shunya Takahashi, T. Nakata, 1999 .

Structural elucidation and synthesis of vialinin C, a new inhibitor of TNF-α production.

Shunya Takahashi, H. Koshino, N. Abe, 2014, Bioorganic & medicinal chemistry.

SYNTHESIS OF A NOVEL AZAPSEUDODISACCHARIDE RELATED TO ALLOSAMIDIN EMPLOYING N, N'-DIACETYLCHITOBIOSE AS A KEY STARTING MATERIAL

Shunya Takahashi, H. Koshino, H. Kuzuhara, 1999 .

Synthetic studies on a potential endoglycosidase inhibitor: Chemical conversion of N,N′-diacetylchitobiose into a pseudodisaccharide containing 2-acetamido-1,2-dideoxynojirimycin

Shunya Takahashi, H. Kuzuhara, H. Terayama, 1996 .

Stereocontrolled synthesis of (−)-allosamizoline using D-glucosamine as a chiral template

Shunya Takahashi, H. Kuzuhara, H. Terayama, 1991 .

Preparation of a Highly Functionalized Cyclopentane Derivative Suitable for the Synthesis of Allosamidin Analogs

Shunya Takahashi, H. Kuzuhara, H. Inoue, 1995 .

Synthesis and structural revision of a brominated sesquiterpenoid, aldingenin C.

Shunya Takahashi, Ken Hatano, K. Matsuoka, 2014, The Journal of organic chemistry.

Design and Synthesis of a Potential Endoglycosidase Inhibitor: Chemical Conversion of N,N′-Diacetylchitobiose into Novel Pseudodisaccharide Containing a Fivemembered Cyclic N,N-Dimethylguanidine

Shunya Takahashi, H. Koshino, H. Kuzuhara, 1996 .

Total Synthesis of the Proposed Structure for Aromin and Its Structural Revision.

Shunya Takahashi, H. Koshino, D. Satoh, 2016, The Journal of organic chemistry.

An immunosuppressive effect by synthetic sulfonolipids deduced from sulfonoquinovosyl diacylglycerols of sea urchin

K. Sakaguchi, F. Sugawara, Y. Mizushina, 2002, Transplantation.

Structure-function relationship of synthetic sulfoquinovosyl-acylglycerols as mammalian DNA polymerase inhibitors.

K. Sakaguchi, F. Sugawara, H. Yoshida, 2002, Archives of biochemistry and biophysics.

Structural determination of sulfoquinovosyldiacylglycerol by chiral syntheses

K. Sakaguchi, F. Sugawara, Y. Mizushina, 2000 .

Total synthesis of an antitumor agent, mucocin, based on the "chiron approach".

Shunya Takahashi, T. Nakata, 2002, The Journal of organic chemistry.

Unified enantioselective total synthesis of 3,6-dioxygenated diketopiperazine natural products, diatretol and lepistamides A, B and C

Shunya Takahashi, Takeshi Yamada, T. Sunazuka, 2021 .

Total Synthesis of ( + )-Methyl Phaseates

Shunya Takahashi, T. Oritani, K. Yamashita, 1986 .

Synthesis of polyozellin, a prolyl oligopeptidase inhibitor, and its structural revision.

Shunya Takahashi, H. Koshino, K. Kimura, 2018, Bioorganic & medicinal chemistry letters.

Structural revision of kynapcin-12 by total synthesis, and inhibitory activities against prolyl oligopeptidase and cancer cells.

Shunya Takahashi, K. Matsuoka, H. Koshino, 2014, Bioorganic & medicinal chemistry letters.

Vialinin A is a ubiquitin-specific peptidase inhibitor.

S. Yajima, Shunya Takahashi, Yasukiyo Yoshioka, 2013, Bioorganic & medicinal chemistry letters.

Synthesis of Atromentin and Its O-Alkylated Natural Products

Shunya Takahashi, D. Hashizume, H. Koshino, 2010, Bioscience, biotechnology, and biochemistry.

Studies on Natural p-Terphenyls: Total Syntheses of Vialinin A and Terrestrin B

Shunya Takahashi, H. Koshino, N. Abe, 2010, Bioscience, biotechnology, and biochemistry.

Expeditious synthesis of vialinin B, an extremely potent inhibitor of TNF-alpha production.

Shunya Takahashi, H. Koshino, N. Abe, 2009, Organic letters.

Structural revision of thelephantin G by total synthesis and the inhibitory activity against TNF-alpha production.

Shunya Takahashi, H. Koshino, N. Abe, 2009, The Journal of organic chemistry.

First Total Synthesis of Vialinin A, a Novel and Extremely Potent Inhibitor of TNF-α Production

Shunya Takahashi, H. Koshino, J. Onose, 2007 .

Vialinin A, a Novel 2,2-Diphenyl-1-picrylhydrazyl (DPPH) Radical Scavenger from an Edible Mushroom in China

Shunya Takahashi, H. Koshino, N. Abe, 2005, Bioscience, biotechnology, and biochemistry.

A new method for determining positions of phenolic hydroxyl groups through silylation and application of H(Si)C triple-resonance NMR experiments

Shunya Takahashi, H. Koshino, M. Maloň, 2007 .

Total synthesis of dehydroaltenusin

K. Sakaguchi, F. Sugawara, Y. Mizushina, 2003 .

Total Synthesis of Dehydroaltenusin.

K. Sakaguchi, F. Sugawara, Y. Mizushina, 2003 .

Facile Preparation of a Phenyl 1-Thioglycoside of Allopyranosylallopyranose from Allyl N,N′-Diacetylchitobioside

Shunya Takahashi, N. Sakairi, H. Kuzuhara, 1994 .

Large-Scale Preparation of N, N'-Diacetylchitobiose by Enzymic Degradation of Chitin and its Chemical Modifications

Shunya Takahashi, H. Kuzuhara, H. Terayama, 1993 .

Total synthesis of (±)-drummondone A

Shunya Takahashi, T. Oritani, K. Yamashita, 1988 .

Synthesis of Amphiphilic Chitopentaose and Chitoheptaose Derivatives Using a Common Disaccharidic Synthon as the Chain Elongation Unit

A. Umino, Shunya Takahashi, K. Matsuoka, 2000 .

Synthesis of Amphiphilic Chitoheptaose Derivative

A. Umino, Shunya Takahashi, K. Matsuoka, 1997 .

Large-Scale Preparation of N,N′-Diacetylchitobiose by Enzymic Degradation of Chitin and Its Chemical Modifications.

Shunya Takahashi, H. Kuzuhara, H. Terayama, 1994 .

Synthesis of demethylallosamidin, a yeast chitinase inhibitor; use of disaccharide glycosyl donor carrying novel neighboring group

Shunya Takahashi, H. Kuzuhara, H. Terayama, 1994 .

One-Pot p-Toluenesulfonylation of Adenosine and Methyl Glycosides with a Substoichiometric Amount of Organotin Mediators

Shunya Takahashi, M. Tsujimoto, M. Kawana, 2000 .

Syntheses of L-fucopyranose and its homologs with ring heteroatoms other than oxygen. Stereocontrolled conversion of a common D-arabinofuranoside intermediate

Shunya Takahashi, H. Kuzuhara, 1992 .

Synthesis of Demethylallosamidin, a Yeast Chitinase Inhibitor; Use of Disaccharide Glycosyl Donor Carrying Novel Neighboring Group.

Shunya Takahashi, H. Kuzuhara, H. Terayama, 1994 .

Precise structural elucidation of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase alpha.

K. Sakaguchi, F. Sugawara, Y. Mizushina, 2004, Bioorganic & medicinal chemistry.

One-Pot p-Toluenesulfonylation of Adenosine and Methyl Glycosides with a Substoichiometric Amount of Organotin Mediators.

Shunya Takahashi, M. Tsujimoto, M. Kawana, 2000 .

Pheromone gland-specific fatty-acyl reductase of the silkmoth, Bombyx mori

T. Ando, Shunya Takahashi, K. Moto, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Involvement of a bifunctional fatty-acyl desaturase in the biosynthesis of the silkmoth, Bombyx mori, sex pheromone.

T. Ando, K. Imai, Masataka G. Suzuki, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Stereoselective Synthesis of the 3-Hydroxytetrahydropyran Part of Mucocin, an Antitumor Agent, Based on Rearrangement-Ring Expansion Reaction of a Tetrahydrofuran Derivative

Shunya Takahashi, N. Sakairi, T. Nakata, 2000 .

Total synthesis of pederin, a potent insect toxin: the efficient synthesis of the right half, (+)-benzoylpedamide

Shunya Takahashi, J. Kobayashi, T. Nakata, 2002 .

Anti-tumor effects of dehydroaltenusin, a specific inhibitor of mammalian DNA polymerase α

K. Sakaguchi, F. Sugawara, H. Yoshida, 2007 .

Detection of oxygen addition peaks for terpendole E and related indole–diterpene alkaloids in a positive-mode ESI-MS

H. Hirota, Shunya Takahashi, H. Koshino, 2014, Journal of mass spectrometry : JMS.

Excess carotenoids disturb prospective cell-to-cell recognition system in mating responses ofPhycomyces blakesleeanus

Shunya Takahashi, T. Ootaki, T. Noshita, 1996 .

Isolation and Characterization of a Humoral Factor That Stimulates Transcription of the Acyl-CoA-binding Protein in the Pheromone Gland of the Silkmoth, Bombyx mori*

Shunya Takahashi, A. Ohnishi, H. Koshino, 2005, Journal of Biological Chemistry.

Synthesis and biological activities of analogs of D-glucosyl-l-tyrosine, a humoral factor that stimulates transcription of the acyl-CoA binding protein in the pheromone gland of the Silkmoth, Bombyx mori.

Shunya Takahashi, A. Ohnishi, H. Koshino, 2007, Bioorganic & medicinal chemistry.

Structural revision of terpenoids with a (3Z)-2-methyl-3-penten-2-ol moiety by the synthesis of (23E)- and (23Z)-cycloart-23-ene-3beta,25-diols.

Hiroko Satoh, Shunya Takahashi, Hiroyuki Koshino, 2007, The Journal of organic chemistry.

Isolation of Coralmycins A and B, Potent Anti-Gram Negative Compounds from the Myxobacteria Corallococcus coralloides M23.

Shunya Takahashi, H. Koshino, Kyungyun Cho, 2016, Journal of natural products.

Synthesis of ovalicin starting from D-mannose.

Shunya Takahashi, H. Koshino, T. Nakata, 2005, The Journal of organic chemistry.

Isolation, Identification and Synthesis of a New Prenylated Cinnamic Acid Derivative from Brazilian Green Propolis and Simultaneous Quantification of Bioactive Components by LC-MS/MS.

N. Matsuura, Shunya Takahashi, Y. Kimura, 2019, Journal of Agricultural and Food Chemistry.

Total synthesis of the proposed structure for pochonicine and determination of its absolute configuration

Shunya Takahashi, K. Matsuoka, H. Koshino, 2013 .