D. Johns

发表

Cyclin D1 Repression of Peroxisome Proliferator-Activated Receptor γ Expression and Transactivation

Lawrence A. Donehower, Philipp E. Scherer, Michael Brownlee, 2003, Molecular and Cellular Biology.

Krüppel-like Factor 4 (Gut-enriched Krüppel-like Factor) Inhibits Cell Proliferation by Blocking G1/S Progression of the Cell Cycle*

E. Marbán, D. Geiman, D. Dang, 2001, The Journal of Biological Chemistry.

Probing the Interaction Between Inactivation Gating and d-Sotalol Block of HERG

J. Balser, G. Tomaselli, D. Johns, 2000, Circulation research.

IKr drug response is modulated by KCR1 in transfected cardiac and noncardiac cell lines

D. Roden, J. Balser, A. George, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Ultrarapid, highly efficient viral gene transfer to the heart.

E. Marbán, D. Johns, J. Lawrence, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Cell-specific promoter in adenovirus vector for transgenic expression of SERCA1 ATPase in cardiac myocytes.

C. Strock, D. Johns, P. Kessler, 1998, American journal of physiology. Cell physiology.

Expression of inwardly rectifying potassium channels by an inducible adenoviral vector reduced the neuronal hyperexcitability and hyperalgesia produced by chronic compression of the spinal ganglion

R. LaMotte, J. Rosenzweig, D. Johns, 2010, Molecular pain.

Modulation of Kv4-encoded K+ Currents in the Mammalian Myocardium by Neuronal Calcium Sensor-1*

J. Nerbonne, A. Jeromin, D. Johns, 2002, The Journal of Biological Chemistry.

Viral Gene Transfer of Dominant-Negative Kv4 Construct Suppresses an O2-Sensitive K+ Current in Chemoreceptor Cells

E. Marbán, Constancio González, D. Johns, 2000, The Journal of Neuroscience.

JAM-A is both essential and inhibitory to development of hepatic polarity in WIF-B cells.

Arun J Sharma, D. Johns, L. Braiterman, 2008, American journal of physiology. Gastrointestinal and liver physiology.

JAM-A is both essential and inhibitory to the development of hepatic polarity in WIF-B cells Running title : JAMA in hepatic polarity

Arun J Sharma, D. Johns, L. Braiterman, 2007 .

Pharmacological and histochemical distinctions between molecularly defined sarcolemmal KATP channels and native cardiac mitochondrial KATP channels.

Yongge Liu, E. Marbán, B. O’Rourke, 1999, Molecular pharmacology.

Suppression of KATP currents by gene transfer of a dominant negative Kir6.2 construct

Yongge Liu, E. Marbán, B. O’Rourke, 1998, Pflügers Archiv.

Molecular composition of mitochondrial ATP-sensitive potassium channels probed by viral Kir gene transfer.

E. Marbán, B. O’Rourke, D. Johns, 2000, Journal of molecular and cellular cardiology.

Ex vivo cultured megakaryocytes express functional glycoprotein IIb-IIIa receptors and are capable of adenovirus-mediated transgene expression.

J. Dipersio, D. Johns, P. Bray, 1999, Blood.

Expression of the adenovirus E4 34k oncoprotein inhibits repair of double strand breaks in the cellular genome of a 293-based inducible cell line.

D. Johns, G. Ketner, Elizabeth A. Ketner, 2004, Nucleic acids research.

902. Modulation of Voltage-Gated Potassium Channels in Dorsal Root Ganglion Neurons by an Inducible Adenoviral Vector In Vivo

R. LaMotte, J. Rosenzweig, D. Johns, 2006 .

Constitutively Active Phosphatidylinositol 3-Kinase and AKT Are Sufficient to Stimulate the Epithelial Na+/H+ Exchanger 3*

M. Cavet, P. Tsichlis, M. Donowitz, 2001, The Journal of Biological Chemistry.

Differences in the Ways Sympathetic Neurons and Endocrine Cells Process, Store, and Secrete Exogenous Neuropeptides and Peptide-Processing Enzymes

R. Mains, D. Johns, R. Marx, 1999, The Journal of Neuroscience.

Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets.

P. MacDonald, E. Marbán, C. Chan, 1999, Diabetes.

Identification of a highly conserved region at the 5' flank of the phospholamban gene.

A. Feldman, D. Johns, 1992, Biochemical and biophysical research communications.

Regulation of endothelial thrombomodulin expression by inflammatory cytokines is mediated by activation of nuclear factor-kappa B.

R. H. Sohn, K. Gardner, D. Johns, 2005, Blood.

Absence of direct delivery for single transmembrane apical proteins or their "Secretory" forms in polarized hepatic cells.

D. Johns, L. Braiterman, A. Hubbard, 2002, Molecular biology of the cell.

Androgen receptor attenuation of Ad5 replication: implications for the development of conditionally replication competent adenoviruses.

J. Hsieh, D. Johns, W. Chowdhury, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

Manipulation of Cellular Excitability by Cell Fusion Effects of Rapid Introduction of Transient Outward K (cid:49) Current on the Guinea Pig Action Potential Rapid Communication

E. Marbán, B. O’Rourke, D. Johns, 1999 .

Potassium channels Kv1.3 and Kv1.5 are expressed on blood‐derived dendritic cells in the central nervous system

P. Calabresi, C. Cudrici, H. Rus, 2006, Annals of neurology.

Functional consequences of the arrhythmogenic G306R KvLQT1 K+ channel mutant probed by viral gene transfer in cardiomyocytes

E. Marbán, D. Johns, U. Hoppe, 2001, The Journal of physiology.

Virus‐Mediated Modification of Cellular Excitability

E. Marbán, D. Johns, H. B. Nuss, 1999, Annals of the New York Academy of Sciences.

Phenotypic characterization of a novel long-QT syndrome mutation (R1623Q) in the cardiac sodium channel.

J. Balser, G. Tomaselli, E. Marbán, 1998, Circulation.

Molecular dissection of cardiac repolarization by in vivo Kv4.3 gene transfer.

E. Marbán, D. Johns, U. Hoppe, 2000, The Journal of clinical investigation.

Evidence against Functional Heteromultimerization of theK ATP Channel Subunits Kir6.1 and Kir6.2*

E. Marbán, B. O’Rourke, D. Johns, 2000, The Journal of Biological Chemistry.

(cid:1) -Adrenergic Stimulation of L-type Ca 2 (cid:2) Channels in Cardiac Myocytes Requires the Distal Carboxyl Terminus of (cid:3) 1C but Not Serine 1928

B. O’Rourke, D. Johns, C. Maack, 2006 .

Connexin43 Expression Levels Influence Intercellular Coupling and Cell Proliferation of Native Murine Cardiac Fibroblasts

E. Kardami, D. Johns, Kathryn A. Yamada, 2008, Cell communication & adhesion.

Local anesthetics as effectors of allosteric gating. Lidocaine effects on inactivation-deficient rat skeletal muscle Na channels.

J. Balser, G. Tomaselli, E. Marbán, 1996, The Journal of clinical investigation.

Characterization of proximal transcription regulatory elements in the rat phospholamban promoter.

A. Feldman, D. Johns, C. McTiernan, 1999, Journal of molecular and cellular cardiology.

A functional assay for paralytic shellfish toxins that uses recombinant sodium channels.

G. Tomaselli, E. Marbán, D. Johns, 2001, Toxicon : official journal of the International Society on Toxinology.

Inducible Genetic Suppression of Neuronal Excitability

R. Mains, E. Marbán, B. O’Rourke, 1999, The Journal of Neuroscience.

Poly(ADP-Ribose) Polymerase Impairs Early and Long-Term Experimental Stroke Recovery

S. Mori, B. Crain, R. Xue, 2002, Stroke.

Suppression of Neuronal and Cardiac Transient Outward Currents by Viral Gene Transfer of Dominant-Negative Kv4.2 Constructs*

E. Marbán, D. Johns, H. B. Nuss, 1997, The Journal of Biological Chemistry.

Distinct gene-specific mechanisms of arrhythmia revealed by cardiac gene transfer of two long QT disease genes, HERG and KCNE1

E. Marbán, D. Johns, U. Hoppe, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Adenovirus-mediated inducible gene expression in vivo by a hybrid ecdysone receptor.

E. Marbán, D. Johns, U. Hoppe, 2000, Molecular therapy : the journal of the American Society of Gene Therapy.

Potassium channel overexpression

E. Marbán, B. O’Rourke, D. Johns, 2000 .

Prospects for genetic manipulation of cardiac excitability.

E. Marbán, D. Johns, J. Lawrence, 1995, Advances in experimental medicine and biology.

Stoichiometric inhibition of mammalian dihydrofolate reductase by the gamma-glutamyl metabolite of methotrexiate, 4-amino-4-deoxy-N-10-methylpteroylglutamyl-gamma-glutamate.

R. Adamson, D. Johns, B. Chabner, 1975, Biochemical and biophysical research communications.

Novel functional properties of Ca2+ channel β subunits revealed by their expression in adult rat heart cells

E. Marbán, D. T. Yue, D. Johns, 2002, The Journal of physiology.

K+ Channel Regulator KCR1 Suppresses Heart Rhythm by Modulating the Pacemaker Current If

D. Johns, U. Hoppe, G. Michels, 2008, PloS one.

Adenovirus-mediated Transfer of CCAAT/Enhancer-binding Protein- Identifies a Dominant Antiproliferative Role for This Isoform in Hepatocytes (*)

D. Johns, J. Lawrence, A. Diehl, 1996, The Journal of Biological Chemistry.

&bgr;-Adrenergic Stimulation of L-type Ca2 Channels in Cardiac Myocytes Requires the Distal Carboxyl Terminus of &agr;1C but Not Serine 1928

B. O’Rourke, D. Johns, C. Maack, 2006, Circulation research.

Manipulation of cellular excitability by cell fusion: effects of rapid introduction of transient outward K+ current on the guinea pig action potential.

E. Marbán, B. O’Rourke, D. Johns, 1999, Circulation research.

Role of Heteromultimers in the Generation of Myocardial Transient Outward K+ Currents

J. Nerbonne, K. Rhodes, J. Trimmer, 2002, Circulation research.

Functional expression of exogenous proteins in mammalian sensory hair cells infected with adenoviral vectors.

J. R. Holt, D. Corey, E. Marbán, 1999, Journal of neurophysiology.

Overexpression of a human potassium channel suppresses cardiac hyperexcitability in rabbit ventricular myocytes.

E. Marbán, D. Johns, H. B. Nuss, 1999, The Journal of clinical investigation.

Reversal of potassium channel deficiency in cells from failing hearts by adenoviral gene transfer: a prototype for gene therapy for disorders of cardiac excitability and contractility.

D. Kass, G. Tomaselli, E. Marbán, 1996, Gene therapy.

Adenovirus-mediated expression of a voltage-gated potassium channel in vitro (rat cardiac myocytes) and in vivo (rat liver). A novel strategy for modifying excitability.

E. Marbán, D. Johns, J. Lawrence, 1995, The Journal of clinical investigation.

Reverse engineering the L-type Ca2+ channel alpha1c subunit in adult cardiac myocytes using novel adenoviral vectors.

B. O’Rourke, D. Johns, C. Maack, 2005, Biochemical and biophysical research communications.

Inward rectifier K+ channel from human heart and brain: cloning and stable expression in a human cell line.

G. Tomaselli, B. O’Rourke, D. Johns, 1995, The American journal of physiology.

Delivering Ion Channels to Mammalian Cells by Membrane Fusion

E. Marbán, B. O’Rourke, D. Johns, 2001 .

Results Expression of Kv 4 . 2 and Kv 4 . 3 in Adult Mouse Ventricles

J. Nerbonne, K. Rhodes, J. Trimmer, 2002 .

Suppression of electrical alternans by overexpression of HERG in canine ventricular myocytes.

Robert F Gilmour, R. Gilmour, D. Johns, 2004, American journal of physiology. Heart and circulatory physiology.