V. Krasnykh

发表

Treatment of ovarian cancer with a tropism modified oncolytic adenovirus.

D. Nettelbeck, R. Alemany, D. Curiel, 2002, Cancer research.

Advances in Brief Treatment of Ovarian Cancer with a Tropism Modified Oncolytic Adenovirus 1

D. Nettelbeck, R. Alemany, D. Curiel, 2002 .

Modulation of Adenovirus Vector Tropism via Incorporation of Polypeptide Ligands into the Fiber Protein

D. Curiel, V. Krasnykh, N. Belousova, 2002, Journal of Virology.

Her2-specific multivalent adapters confer designed tropism to adenovirus for gene targeting.

A. Plückthun, P. Forrer, I. Jelesarov, 2011, Journal of molecular biology.

An Adenovirus Vector with Genetically Modified Fibers Demonstrates Expanded Tropism via Utilization of a Coxsackievirus and Adenovirus Receptor-Independent Cell Entry Mechanism

C. Miller, D. Curiel, Minghui Wang, 1998, Journal of Virology.

Approaches to Utilize Mesenchymal Progenitor Cells as Cellular Vehicles

D. Curiel, V. Krasnykh, L. Pereboeva, 2003, Stem cells.

A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency.

R. Alemany, D. Curiel, P. Reynolds, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Targeting adenovirus to the serotype 3 receptor increases gene transfer efficiency to ovarian cancer cells.

D. Curiel, A. Hemminki, A. Kanerva, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Genetically Targeted Adenovirus Vector Directed to CD40-Expressing Cells

D. Curiel, V. Krasnykh, G. Mikheeva, 2003, Journal of Virology.

Characterization of an Adenovirus Vector Containing a Heterologous Peptide Epitope in the HI Loop of the Fiber Knob

C. Miller, D. Curiel, I. Dmitriev, 1998, Journal of Virology.

Infectivity enhanced, cyclooxygenase-2 promoter-based conditionally replicative adenovirus for pancreatic cancer.

D. Curiel, Masato Yamamoto, Minghui Wang, 2003, Gastroenterology.

An advanced generation of adenoviral vectors selectively enhances gene transfer for ovarian cancer gene therapy approaches.

D. Curiel, C. Rancourt, M. Wang, 1999, Gynecologic oncology.

Advanced generation adenoviral vectors possess augmented gene transfer efficiency based upon coxsackie adenovirus receptor-independent cellular entry capacity.

D. Curiel, J. Xiang, I. Dmitriev, 2000, Cancer research.

Therapeutic molecular targeting of 15-lipoxygenase-1 in colon cancer.

Jeffrey S. Morris, I. Shureiqi, B. Fang, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

Oncolytic adenovirus retargeted to Delta-EGFR induces selective antiglioma activity

K. Aldape, H. Jiang, R. Alemany, 2009, Cancer Gene Therapy.

Infectivity-Enhanced Cyclooxygenase-2-Based Conditionally Replicative Adenoviruses for Esophageal Adenocarcinoma Treatment

Masato Yamamoto, Minghui Wang, V. Krasnykh, 2004, Cancer Research.

Chapter 8 – Targeted Adenoviral Vectors I: Transductional Targeting

V. Krasnykh, J. Douglas, J. T. Douglas, 2002 .

Promoter-controlled infectivity-enhanced conditionally replicative adenoviral vectors for the treatment of gastric cancer

H. Shimada, D. Curiel, P. Reynolds, 2004, Journal of Gastroenterology.

A system for the propagation of adenoviral vectors with genetically modified receptor specificities

C. Miller, D. Curiel, I. Dmitriev, 1999, Nature Biotechnology.

Efficient Gene Transduction by RGB‐fiber Modified Recombinant Adenovirus into Dendritic Cells

D. Curiel, H. Wakasugi, Y. Heike, 2001, Japanese journal of cancer research : Gann.

Reduction of ischemia-reperfusion injury of the liver by in vivo adenovirus-mediated gene transfer of the antiapoptotic Bcl-2 gene.

J. Contreras, D. Curiel, J. Thomas, 1999, Annals of surgery.

Genetic modification of liver grafts with an adenoviral vector encoding the Bcl-2 gene improves organ preservation.

J. Contreras, D. Curiel, J. Thomas, 1999, Transplantation.

Development of a therapeutic adenoviral vector for cholangiocarcinoma combining tumor-restricted gene expression and infectivity enhancement

D. Curiel, K. Takayama, Masato Yamamoto, 2003, Journal of Gastrointestinal Surgery.

Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism

D. Curiel, V. Krasnykh, J. Douglas, 1996, Journal of virology.

Targeting ofAdenovirus via Genetic Modification of the Viral Capsid Combined with aProteinBridge

D. Curiel, V. Krasnykh, G. Mikheeva, 2003, Journal of Virology.

Genetic cytoprotection of human endothelial cells during preservation time with an adenoviral vector encoding the anti-apoptotic human Bcl-2 gene.

J. Contreras, D. Curiel, J. Thomas, 1999, Transplantation proceedings.

Cell cycle arrest and apoptosis induced by SART-1 gene transduction.

D. Curiel, H. Wakasugi, Y. Heike, 2005, Anticancer research.

Modification of Adenovirus Capsid with a Designed Protein Ligand Yields a Gene Vector Targeted to a Major Molecular Marker of Cancer

V. Krasnykh, G. Mikheeva, J. Gelovani, 2007, Journal of Virology.

Mode of transgene expression after fusion to early or late viral genes of a conditionally replicating adenovirus via an optimized internal ribosome entry site in vitro and in vivo.

D. Nettelbeck, A. Rivera, D. Curiel, 2004, Virology.

Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters

A. Plückthun, A. Honegger, M. Grütter, 2013, Proceedings of the National Academy of Sciences.

Modification of Adenovirus Receptor Specificity by Designed Multivalent Targeting Adapters

A. Plückthun, P. Forrer, I. Jelesarov, 2010 .

Ectodomain of Coxsackievirus and Adenovirus Receptor Genetically Fused to Epidermal Growth Factor Mediates Adenovirus Targeting to Epidermal Growth Factor Receptor-Positive Cells

D. Curiel, I. Dmitriev, V. Krasnykh, 2000, Journal of Virology.

Fiber knob modifications overcome low, heterogeneous expression of the coxsackievirus-adenovirus receptor that limits adenovirus gene transfer and oncolysis for human rhabdomyosarcoma cells.

D. Curiel, J. Bergelson, V. Krasnykh, 2001, Cancer research.

Rhabdomyosarcoma Cells Limits Adenovirus Gene Transfer and Oncolysis for Human Expression of the Coxsackievirus-Adenovirus Receptor That Fiber Knob Modifications Overcome Low , Heterogeneous Updated

D. Curiel, J. Bergelson, V. Krasnykh, 2001 .

Blood-based Screening and Light Based Imaging for the Early Detection and Monitoring of Ovarian Cancer Xenografts

E. Partridge, V. Krasnykh, K. Zinn, 2003, Technology in cancer research & treatment.

TITLE: Derivation of Targeted Phage Vectors for Gene Therapy of Prostate Cancer

Principal Investigator, V. Krasnykh, 2006 .

Bacterial expression and kinetic characterization of the human monoamine-sulfating form of phenol sulfotransferase.

C. Falany, V. Krasnykh, T. Ganguly, 1995, Drug metabolism and disposition: the biological fate of chemicals.

Genetic Targeting of an Adenovirus Vector via Replacement of the Fiber Protein with the Phage T4 Fibritin

D. Curiel, V. Krasnykh, G. Mikheeva, 2001, Journal of Virology.

Bacterial expression and characterization of a cDNA for human liver estrogen sulfotransferase

C. Falany, V. Krasnykh, J. Falany, 1995, The Journal of Steroid Biochemistry and Molecular Biology.

Adenovirus a pouvoir infectant renforce et a replication conditionnelle, et applications de celui-ci

R. Alemany, D. Curiel, I. Dmitriev, 2000 .

Substitution of the adenovirus serotype 5 knob with a serotype 3 knob enhances multiple steps in virus replication.

D. Curiel, V. Krasnykh, J. Blackwell, 2003, Cancer research.

Molecular imaging of active mutant L858R EGF receptor (EGFR) kinase-expressing nonsmall cell lung carcinomas using PET/CT

V. Krasnykh, K. Ogawa, J. Gelovani, 2011, Proceedings of the National Academy of Sciences.

Adenovirus-Mediated Gene Expression In Vivo Is Enhanced by the Antiapoptotic Bcl-2 Gene

J. Contreras, D. Curiel, G. Bilbao, 1999, Journal of Virology.

Identification of Sites in Adenovirus Hexon for Foreign Peptide Incorporation

D. Curiel, Hongju Wu, I. Dmitriev, 2005, Journal of Virology.

Native and engineered tropism of vectors derived from a rare species D adenovirus serotype 43

C. Xiong, Chun Xing Li, P. Fox, 2016, Oncotarget.

A mosaic adenovirus possessing serotype Ad5 and serotype Ad3 knobs exhibits expanded tropism.

M. Rots, D. Curiel, P. Reynolds, 2003, Virology.

Adenoviral gene therapy for renal cancer requires retargeting to alternative cellular receptors.

D. Curiel, S. Naito, A. Hemminki, 2002, Cancer research.

Genetic targeting of adenoviral vectors.

V. Krasnykh, V. V. van Beusechem, J. Douglas, 2000, Molecular therapy : the journal of the American Society of Gene Therapy.

HSV-1 virions engineered for specific binding to cell surface receptors.

P. Grandi, X. Breakefield, D. Curiel, 2004, Molecular therapy : the journal of the American Society of Gene Therapy.

Development of a Targeted Gene Vector Platform Based on Simian Adenovirus Serotype 24

L. Bidaut, C. Xiong, Chun Xing Li, 2010, Journal of Virology.

Adenoviruses with an RGD-4C modification of the fiber knob elicit a neutralizing antibody response but continue to allow enhanced gene delivery.

B. Liu, D. Curiel, A. Hemminki, 2005, Gynecologic oncology.

Selective gene delivery to head and neck cancer cells via an integrin targeted adenoviral vector.

K. Kasono, D. Curiel, I. Dmitriev, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

A Strategy for Adenovirus Vector Targeting with a Secreted Single Chain Antibody

D. Curiel, V. Krasnykh, G. Mikheeva, 2009, PloS one.

Adenovirus-mediated gene delivery to dendritic cells.

D. Curiel, V. Krasnykh, L. Timares, 2004, Methods in molecular biology.

Bioluminescence imaging reveals a significant role for complement in liver transduction following intravenous delivery of adenovirus

K. Zinn, T. Chaudhuri, V. Krasnykh, 2004, Gene Therapy.

Gamma camera dual imaging with a somatostatin receptor and thymidine kinase after gene transfer with a bicistronic adenovirus in mice.

D. Curiel, W. Grizzle, V. Krasnykh, 2002, Radiology.

Isolation and expression of an isoform of rat estrogen sulfotransferase

C. Falany, V. Krasnykh, G. Mikheeva, 1995, The Journal of Steroid Biochemistry and Molecular Biology.

Adenoviral-mediated delivery of herpes simplex virus thymidine kinase results in tumor reduction and prolonged survival in a SCID mouse model of human ovarian carcinoma

D. Curiel, M. Wang, G. Siegal, 1996, Journal of Molecular Medicine.

Advanced Methods of Adenovirus Vector Production for Human Gene Therapy: Roller Bottles, Microcarriers, and Hollow Fibers

V. Krasnykh, T. Isayeva, A. Kotov, 2003 .

Improved gene transfer efficiency to primary and established human pancreatic carcinoma target cells via epidermal growth factor receptor and integrin-targeted adenoviral vectors

P. Bosma, D. Curiel, P. Reynolds, 2001, Gene Therapy.

The coxsackievirus and adenovirus receptor acts as a tumour suppressor in malignant glioma cells

M. Kim, V. Krasnykh, N. Belousova, 2003, British Journal of Cancer.

The therapeutic efficacy of adenoviral vectors for cancer gene therapy is limited by a low level of primary adenovirus receptors on tumour cells.

David T. Curiel, Joanne T. Douglas, Myunghee Kim, 2002, European journal of cancer.

Combining high selectivity of replication with fiber chimerism for effective adenoviral oncolysis of CAR-negative melanoma cells

D. Nettelbeck, A. Rivera, D. Curiel, 2004, Gene Therapy.

Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters

A. Plückthun, A. Honegger, M. Grütter, 2013, Proceedings of the National Academy of Sciences.

Using a tropism-modified adenoviral vector to circumvent inhibitory factors in ascites fluid.

C. Richter, D. Curiel, H. Li, 2000, Human gene therapy.