P. Baeuerle

D. Olive, P. Baeuerle, J. Imbert, 1993, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Developmental and tissue-specific expression of the Q5k gene

G. Brem, P. Baeuerle, E. Weiss, 1991, Immunogenetics.

KBF 1 ( p 50 NF-gB Homodimer ) . Acts as a Repressor of H-2 K b Gene Expression in Metastatic Tumor Cells

P. Baeuerle, L. Eisenbach, D. Plaksin, 1993 .

Recent advances towards understanding redox mechanisms in the activation of nuclear factor kappaB.

P. Baeuerle, Y. Janssen-Heininger, M. Poynter, 2000, Free radical biology & medicine.

Cytotoxic activity of novel human monoclonal antibody MT201 against primary ovarian tumor cells

R. Kimmig, P. Baeuerle, J. Diebold, 2003, Journal of Cancer Research and Clinical Oncology.

Selective targeting and potent control of tumor growth using an EphA2/CD3-Bispecific single-chain antibody construct.

P. Kufer, R. Lutterbuese, P. Kiener, 2007, Cancer research.

Mode of cytotoxic action of T cell-engaging BiTE antibody MT110.

P. Hoffmann, P. Kufer, P. Baeuerle, 2009, Immunobiology.

A human cytokine/single-chain antibody fusion protein for simultaneous delivery of GM-CSF and IL-2 to Ep-CAM overexpressing tumor cells.

P. Kufer, P. Baeuerle, T. Dreier, 2006, Cancer immunity.

Selective activation of NF-kappa B by nerve growth factor through the neurotrophin receptor p75.

Y. Barde, P. Baeuerle, C. Kaltschmidt, 1996, Science.

Antioxidant and redox regulation of genes

C. Sen, P. Baeuerle, H. Sies, 1999 .

Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis

W. Fiers, K. Schulze-Osthoff, P. Krammer, 1995, Nature.

The primary structure of bovine chromogranin A: a representative of a class of acidic secretory proteins common to a variety of peptidergic cells.

J. Mallet, W. Huttner, P. Baeuerle, 1986, The EMBO journal.

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF‐kappa B transcription factor and HIV‐1.

P. Baeuerle, R. Schreck, P. Rieber, 1991, The EMBO journal.

Requires an Enhanced Intracellular Tax-Mediated Apoptosis in Activated T Cells Human T Cell Leukemia Virus-I (HTLV-I)

K. Schulze-Osthoff, P. Baeuerle, V. Schirrmacher, 2013 .

Regulation of Gene Expression by Oxidative Stress

K. Schulze-Osthoff, P. Baeuerle, 1998 .

Human T Cell Leukemia Virus-I ( HTLV-I ) Tax-Mediated Apoptosis in Activated T Cells Requires an Enhanced Intracellular Prooxidant State 1

K. Schulze-Osthoff, P. Baeuerle, K. Chlichlia, 1998 .

Induction of Oxidative Stress by Okadaic Acid Is Required for Activation of Transcription Factor NF-κB (*)

P. Baeuerle, K. Schmidt, B. Meier, 1995, The Journal of Biological Chemistry.

Differential activation of transcription factors NF‐ϰB and AP‐1 in rat liver macrophages

K. Decker, P. Baeuerle, T. Tran-Thi, 1995 .

[14] Assessing oxygen radicals as mediators in activation of inducible eukaryotic transcription factor NF-κB

P. Baeuerle, R. Schreck, 1994 .

Selection of a muramyl peptide based on its lack of activation of nuclear factor‐κB as a potential adjuvant for AIDS vaccines

P. Baeuerle, L. Chedid, G. Bahr, 1992, Clinical and experimental immunology.

Tumor necrosis factor β (TNF-β) induces binding of the NF-κB transcription factor to a high-affinity κB element in the TNF-β promoter

P. Baeuerle, E. Weiss, G. Messer, 1990 .

Recent advances torwards understanding redox mechanisms in the activation of nuclear factor κb

P. Baeuerle, Y. Janssen-Heininger, M. Poynter, 2000 .

Transcription factor NF-kB/Rel is activated in the atherosclerotic lesion.

R. Knuechel, G. Rogler, P. Baeuerle, 1996 .

Endoplasmicreticulum-induced signal transduction and gene expression.

H. Pahl, P. Baeuerle, Heiki L. Pahl, 1997, Trends in cell biology.

Sphingomyelinase activates proteolytic I kappa B-alpha degradation in a cell-free system.

P. Baeuerle, M. Krönke, T. Henkel, 1994, The Journal of biological chemistry.

Resurgence of Bispecific Antibodies

T. Raum, P. Baeuerle, Tobias Raum, 2013 .

Purified I kappa B-beta is inactivated upon dephosphorylation.

U. Zabel, I. Verma, P. Baeuerle, 1992, The Journal of biological chemistry.

Reactive oxygen intermediates as second messengers of a general pathogen response.

H. Pahl, P. Baeuerle, R. Rupec, 1996, Pathologie-biologie.

A Hydrophobic Region within the Adenovirus E1B 19 kDa Protein Is Necessary for the Transient Inhibition of NF-κB Activated by Different Stimuli*

M. Schmitz, P. Baeuerle, F. Limbourg, 1996, The Journal of Biological Chemistry.

Tumor necrosis factor beta (TNF-beta) induces binding of the NF-kappa B transcription factor to a high-affinity kappa B element in the TNF-beta promoter.

P. Baeuerle, E. Weiss, G. Messer, 1990, Cytokine.

Serial killing of tumor cells by cytotoxic T cells redirected with a CD19‐/CD3‐bispecific single‐chain antibody construct

P. Hoffmann, P. Baeuerle, C. Itin, 2005, International journal of cancer.

Brain synapses contain inducible forms of the transcription factor NF-kappa B.

P. Baeuerle, C. Kaltschmidt, B. Kaltschmidt, 1993, Mechanisms of development.

of NF-kappaB by I kappaB. A 65-kappaD subunit of active NF-kappaB is required for inhibition

D. Baltimore, P. Baeuerle, 2011 .

The role of NF-kappa B1 (p50/p105) gene expression in activation of human blood T-lymphocytes via CD2 and CD28 adhesion molecules.

D. Olive, P. Baeuerle, J. Imbert, 1993, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

The physiology of the NF-κB transcription factor

D. Baltimore, P. Baeuerle, 1991 .

The interleukin-2 antagonizing antibody MT204 delays allogeneic skin graft rejection in non-human primates and is well tolerated.

B. Rattel, P. Baeuerle, T. Boehm, 2011, Transplant immunology.

A humanized monoclonal antibody against interleukin-2 that can inactivate the cytokine/receptor complex.

P. Hoffmann, T. Raum, M. Mølhøj, 2007, Molecular immunology.

The 65-kD subunit of NF-KB is a receptor for IKB and a modulator of DNA-binding specificity

P. Baeuerle, M. B. Urban, 2007 .

Interleukin‐1β Uses Common and Distinct Signaling Pathways for Induction of the Interleukin‐6 and Tumor Necrosis Factor α Genes in the Human Astrocytoma Cell Line U373

J. Bauer, B. Fiebich, P. Baeuerle, 1996 .

Purification, reconstitution, and I kappa B association of the c-Rel-p65 (RelA) complex, a strong activator of transcription

P. Baeuerle, F. Blasi, S. Hansen, 1994, Molecular and cellular biology.

Chlorate--a potent inhibitor of protein sulfation in intact cells.

W. Huttner, P. Baeuerle, 1986, Biochemical and biophysical research communications.

A novel complex between the p65 subunit of NF‐kappa B and c‐Rel binds to a DNA element involved in the phorbol ester induction of the human urokinase gene.

U. Zabel, P. Verde, P. Baeuerle, 1992, The EMBO journal.

A human monoclonal IgG1 potently neutralizing the pro-inflammatory cytokine GM-CSF.

T. Raum, A. Wolf, M. Mølhøj, 2007, Molecular immunology.

Regulation of Tumor Necrosis Factor Alpha Transcription in Macrophages: Involvement of Four KB-Like Motifs and of Constitutive and Inducible Forms of NF-KB

P. Baeuerle, M. Collart, 2003 .

Nuclear factor kappa B activates proenkephalin transcription in T lymphocytes

M. Korner, P. Baeuerle, A. Rattner, 1991, Molecular and cellular biology.

Nuclear Factor KB Activates Proenkephalin Transcription in T Lymphocytes

M. Korner, P. Baeuerle, A. Rattner, 2022 .

Distinct Domains of the RelA NF-κB Subunit Are Required for Negative Cross-talk and Direct Interaction with the Glucocorticoid Receptor*

E. Kalkhoven, M. Schmitz, B. van der Burg, 1997, The Journal of Biological Chemistry.

Activation of NF-kappa B precursor.

David Baltimore, D. Baltimore, P. Baeuerle, 1989 .

Bispecific T Cell Engager for Cancer Therapy

P. Baeuerle, G. Zugmaier, D. Rüttinger, 2011 .

Combined blockade of granulocyte-macrophage colony stimulating factor and interleukin 17 pathways potently suppresses chronic destructive arthritis in a tumour necrosis factor α-independent mouse model

P. Baeuerle, W. B. van den Berg, L. Joosten, 2008, Annals of the rheumatic diseases.

Molecular mechanisms in down-regulation of tumor necrosis factor expression.

J. Haas, P. Baeuerle, G. Riethmüller, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Clinical experience with gene therapy and bispecific antibodies for T cell-based therapy of cancer.

P. Baeuerle, C. Itin, 2012, Current pharmaceutical biotechnology.

Human IgG1 antibodies antagonizing activating receptor NKG2D on natural killer cells

P. Hoffmann, P. Kufer, T. Raum, 2009, mAbs.

The activity of γδ T cells against paediatric liver tumour cells and spheroids in cell culture

P. Baeuerle, S. Warmann, S. Armeanu-Ebinger, 2013, Liver international : official journal of the International Association for the Study of the Liver.

A secreted/shed product of Helicobacter pylori activates transcription factor nuclear factor-kappa B.

H. Pahl, P. Baeuerle, S. Bereswill, 1997, Journal of immunology.

Passive immunotherapy by T cell–engaging bispecific antibodies

B. Rattel, P. Baeuerle, 2011 .

Constructions (poly)peptidiques desimmunisees

P. Baeuerle, T. Dreier, M. Zocher, 2003 .

NF-?B as a Frequent Target for Immunosuppressive and

P. Baeuerle, V. R. Baichwal, Vuay R. Baichwal, 1997 .

The effect of dexamethasone on polyclonal T cell activation and redirected target cell lysis as induced by a CD19/CD3-bispecific single-chain antibody construct

P. Kufer, J. Suzich, P. Baeuerle, 2007, Cancer Immunology, Immunotherapy.

Pharmacokinetic and Pharmacodynamic Relationship of Blinatumomab in Patients with Non-Hodgkin Lymphoma

P. Kufer, A. Wolf, P. Baeuerle, 2018, Current clinical pharmacology.

Highly efficient antigen targeting to M-DC8+ dendritic cells via FcgammaRIII/CD16-specific antibody conjugates.

P. Hoffmann, P. Kufer, A. Wolf, 2005, International immunology.

Impact of Diverse Immune Evasion Mechanisms of Cancer Cells on T Cells Engaged by EpCAM/CD3-Bispecific Antibody Construct AMG 110

P. Kufer, T. Raum, P. Baeuerle, 2015, PloS one.

The inducible transcription activator NF-κB: regulation by distinct protein subunits

P. Baeuerle, 1991 .

KBF1 (p50 NF-kappa B homodimer) acts as a repressor of H-2Kb gene expression in metastatic tumor cells

P. Baeuerle, L. Eisenbach, D. Plaksin, 1993, The Journal of experimental medicine.

Strong Activator of Transcription

P. Baeuerle, S. Hansen, Francesco Blasii, 2022 .

CD33 target validation and sustained depletion of AML blasts in long-term cultures by the bispecific T-cell-engaging antibody AMG 330.

W. Hiddemann, K. Metzeler, K. Spiekermann, 2014, Blood.

MYELOID NEOPLASIA CD 33 target validation and sustained depletion of AML blasts in long-term cultures by the bispeci fi c T-cell – engaging antibody AMG 330

W. Hiddemann, K. Metzeler, K. Spiekermann, 2013 .

Characterization of a new tissue-specific transcription factor binding to the simian virus 40 enhancer TC-II (NF-kappa B) element

P. Bucher, A. Israël, P. Baeuerle, 1992, Molecular and cellular biology.

Characterization of a New Tissue-Specific Factor Binding to the Simian Virus 40 TC-II (NF-FB) Element Transcription Enhancer

Catherine, P. Bucher, P. Baeuerle, 2022 .

T lymphocytes can be effectively recruited for ex vivo and in vivo lysis of AML blasts by a novel CD33/CD3-bispecific BiTE antibody construct

A. Mackensen, A. Henn, M. Friedrich, 2013, Leukemia.

Human therapies as a successful liaison between chemistry and biology.

P. Baeuerle, J. Murry, 2014, Chemistry & biology.

The Rel-associated pp40 protein prevents DNA binding of Rel and NF-KB: relationship .with IKBI3 and regulation by phosphorylatlon

Lawrence, I. Verma, H. Bose,, 2007 .

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells

D. Männel, W. Dröge, P. Baeuerle, 1992, The Journal of experimental medicine.

Appearance of apparently ubiquitin-conjugated IκB-α during its phosphorylation-induced degradation in intact cells

P. Baeuerle, E. Traenckner, 1995, Journal of Cell Science.

Antibody Construct CD 19-/ CD 3-Bispecific Single-Chain Human B Cell Lymphoma Xenografts by a Mice Bearing Subcutaneous or Leukemic Efficacious Inhibition of Tumor Growth in T Cell Costimulus-Independent and Very

P. Kufer, I. Fichtner, P. Baeuerle, 2003 .

Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion.

R. Knuechel, G. Rogler, P. Baeuerle, 1996, The Journal of clinical investigation.

Structural analysis, expression, and chromosomal localization of the mouse ikba gene

J. Grosgeorge, R. Schmid, A. Livolsi, 1999, Immunogenetics.

A 65-kD subunit of active NF-KB is required for inhibition of NF-KB by IKB

P. Baeuerle, David Bahimore, 2007 .

Activation of human immunodeficiency virus long terminal repeat by arachidonic acid.

P. Baeuerle, G. Poli, G. Leonarduzzi, 1997, Free radical biology & medicine.

Failure of the splicing variant p65 delta of the NF-kappa B subunit p65 to transform fibroblasts.

P. Baeuerle, S. Grimm, 1994, Oncogene.

H2O2 and antioxidants have opposite effects on activation of NF‐kappa B and AP‐1 in intact cells: AP‐1 as secondary antioxidant‐responsive factor.

P. Baeuerle, M. Meyer, R. Schreck, 1993, The EMBO journal.

Nuclear uptake control of NF‐kappa B by MAD‐3, an I kappa B protein present in the nucleus.

U. Zabel, P. Baeuerle, T. Henkel, 1993, The EMBO journal.

Eradication of tumors from a human colon cancer cell line and from ovarian cancer metastases in immunodeficient mice by a single-chain Ep-CAM-/CD3-bispecific antibody construct.

R. Kimmig, P. Kufer, R. Lutterbuese, 2005, Cancer research.

Therapeutic window of an EpCAM/CD3-specific BiTE antibody in mice is determined by a subpopulation of EpCAM-expressing lymphocytes that is absent in humans

M. Friedrich, R. Kischel, P. Kufer, 2008, Cancer Immunology, Immunotherapy.

T-cell activation and B-cell depletion in chimpanzees treated with a bispecific anti-CD19/anti-CD3 single-chain antibody construct

P. Kufer, P. Baeuerle, C. Brandl, 2006, Cancer Immunology, Immunotherapy.

Preclinical Characterization of HPN536, a Trispecific, T-Cell–Activating Protein Construct for the Treatment of Mesothelin-Expressing Solid Tumors

S. D. Jones, B. Lemon, P. Baeuerle, 2020, Clinical Cancer Research.

Tyrosine sulfation of yolk proteins 1, 2, and 3 in Drosophila melanogaster.

W. Huttner, P. Baeuerle, 1985, The Journal of biological chemistry.

The role of the p50 and p65 subunits of NF-kappa B in the recognition of cognate sequences.

P. Baeuerle, M. B. Urban, 1991, The New biologist.

Targeting T cells to tumor cells using bispecific antibodies.

P. Baeuerle, S. Frankel, 2013, Current opinion in chemical biology.

Tissue with a High Potential to Produce TNF-Cell Area of Mucosa-Associated Lymphoid A Subset of Human Dendritic Cells in the T

G. Baretton, A. Greiner, P. Baeuerle, 2003 .

Regulation of the transcription factors NF-kappa B and AP-1 by redox changes.

H. Pahl, P. Baeuerle, M. Meyer, 1994, Chemico-biological interactions.

Activation of the transcription factor NF-kB in inflamed synovial tissue

P. Baeuerle, P. Mapp, C. Kaltschmidt, 1996 .

In vitro and in vivo activity of MT201, a fully human monoclonal antibody for pancarcinoma treatment

P. Kufer, T. Raum, A. Wolf, 2002, International journal of cancer.

Interleukin-1 beta uses common and distinct signaling pathways for induction of the interleukin-6 and tumor necrosis factor alpha genes in the human astrocytoma cell line U373.

J. Bauer, B. Fiebich, P. Baeuerle, 1996, Journal of neurochemistry.

The primary structure of human secretogranin II, a widespread tyrosine-sulfated secretory granule protein that exhibits low pH- and calcium-induced aggregation.

P. Argos, W. Huttner, H. Gerdes, 1989, The Journal of biological chemistry.

Specific depletion of autoreactive B lymphocytes by a recombinant fusion protein in vitro and in vivo.

P. Baeuerle, T. Dreier, M. Zocher, 2003, International immunology.

Speci ® c depletion of autoreactive B lymphocytes by a recombinant fusion protein in vitro and in vivo

P. Baeuerle, T. Dreier, M. Zocher, 2022 .

Bispecific T cell engaging antibody constructs targeting a universally conserved part of the viral M2 ectodomain cure and prevent influenza A virus infection

W. Fiers, P. Kufer, M. Muenz, 2017, Antiviral research.

Micromet: engaging immune cells for life

P. Baeuerle, Evelyn Wolf, 2002 .

Treatment with Anti-CD19 BiTE Antibody Blinatumomab (MT103 / MEDI-538) Is Able to Eliminate Minimal Residual Disease (MRD) in Patients with B-Precursor Acute Lymphoblastic Leukemia (ALL): First Results of An Ongoing Phase II Study.

P. Kufer, P. Baeuerle, M. Schmid, 2008 .

Novel antineoplastic agents with efficacy against multidrug resistant tumor cells.

P. Baeuerle, V. Baichwal, J. Jaén, 1998, Bioorganic & medicinal chemistry letters.

TriTACs, a Novel Class of T-Cell–Engaging Protein Constructs Designed for the Treatment of Solid Tumors

R. Dubridge, B. Lemon, P. Baeuerle, 2020, Molecular Cancer Therapeutics.

Potential involvement of the transcription factor NF-kappa B in neurological disorders.

P. Baeuerle, C. Kaltschmidt, B. Kaltschmidt, 1993, Molecular aspects of medicine.

Antitumor Activity of a Dual Cytokine/Single-chain Antibody Fusion Protein for Simultaneous Delivery of GM-CSF and IL-2 to Ep-CAM Expressing Tumor Cells

P. Kufer, I. Fichtner, P. Baeuerle, 2006, Journal of immunotherapy.

Abstract 1773: HPN424, a half-life extended, PSMA/CD3-specific TriTAC for the treatment of metastatic prostate cancer

S. D. Jones, B. Lemon, P. Baeuerle, 2018, Immunology.

The NF-kappa B transcription factor induces DNA bending which is modulated by its 65-kD subunit.

E. Winnacker, P. Baeuerle, H. Zorbas, 1990, Nucleic acids research.

Purified human IκB can rapidly dissociate the complex of the NF-κB transcription factor with its cognate DNA

U. Zabel, P. Baeuerle, 1990, Cell.

Phenotype and function of human dendritic cells derived from M‐DC8+ monocytes

P. Baeuerle, Ines Mende, A. de Baey, 2001, European journal of immunology.

Hydrogen peroxide as a potent activator of T lymphocyte functions

K. Schulze-Osthoff, W. Dröge, P. Baeuerle, 1995, European journal of immunology.

Frequent high-level expression of the immunotherapeutic target Ep-CAM in colon, stomach, prostate and lung cancers

M Vasei, J. Kononen, L. Bubendorf, 2006, British Journal of Cancer.

NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules.

P. Baeuerle, V. R. Baichwal, Vuay R. Baichwal, 1997, Advances in immunology.

Expression of influenza virus hemagglutinin activates transcription factor NF-kappa B

H. Pahl, P. Baeuerle, P A Baeuerle, 1995, Journal of virology.

NF-kappa B: ten years after.

D. Baltimore, P. Baeuerle, 1996, Cell.

Anti-psoriatic drug anthralin activates transcription factor NF-kappa B in murine keratinocytes.

L. Packer, P. Baeuerle, K. Schmidt, 1996, Journal of immunology.

The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB

K. Schulze-Osthoff, H. Pahl, T. Decker, 1996, The Journal of experimental medicine.

NF‐kappa B contacts DNA by a heterodimer of the p50 and p65 subunit.

P. Baeuerle, P A Baeuerle, R Schreck, 1991, The EMBO journal.

Protein sulfation on tyrosine

W. Huttner, P. Baeuerle, 1988 .

Inducible Gene Expression, Volume 1

P. Baeuerle, 1995, Progress in Gene Expression.

The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product

A. Israël, J. Vandekerckhove, P. Kourilsky, 1990, Cell.

The roles of hydrogen peroxide and superoxide as messengers in the activation of transcription factor NF-kappa B.

P. Cerutti, P. Baeuerle, K. Schmidt, 1995, Chemistry & biology.

BiTE: a new class of antibodies that recruit T-cells

P. Kufer, P. Baeuerle, C. Reinhardt, 2008 .

Efficient tumor cell lysis by autologous, tumor‐resident T lymphocytes in primary ovarian cancer samples by an EP‐CAM‐/CD3‐bispecific antibody

R. Kimmig, P. Baeuerle, J. Diebold, 2003, International journal of cancer.

Sex reversal by loss of the C–terminal transactivation domain of human SOX9

Gerd Scherer, M. Schmitz, P. Baeuerle, 1996, Nature Genetics.

CEA/CD3 bispecific antibody MEDI-565/AMG 211 activation of T cells and subsequent killing of human tumors is independent of mutations commonly found in colorectal adenocarcinomas

S. Coats, P. Baeuerle, S. Hammond, 2014, mAbs.

Productivity and Quality of Recombinant Proteins Produced by Stable CHO Cell Clones can be Predicted by Transient Expression in HEK Cells

P. Baeuerle, M. Klinger, R. Neef, 2013, Molecular Biotechnology.

Bispecific T-cell engaging antibodies for cancer therapy.

Carsten Reinhardt, P. Baeuerle, C. Reinhardt, 2009, Cancer research.

Tumor Regression in Cancer Patients by Very Low Doses of a T Cell–Engaging Antibody

H. Einsele, P. Kufer, A. Wolf, 2008, Science.

Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa B

P. Baeuerle, P. Vassalli, M. Collart, 1990, Molecular and cellular biology.

Inhibition of N‐glycosylation induces tyrosine sulphation of hybridoma immunoglobulin G.

W. Huttner, P. Baeuerle, 1984, The EMBO journal.

The NF-ϰB transcription factor induces DNA bending which is modulated by its 65-kD subunit

E. Winnacker, P. Baeuerle, R. Schreck, 1990 .

The inducible transcription factor NF-kappa B: structure-function relationship of its protein subunits.

P. Baeuerle, S. Grimm, Stefan Grimm, 1993, The Biochemical journal.

Antioxidants selectively suppress activation of NF-kappa B by human T-cell leukemia virus type I Tax protein

B. Fleckenstein, P. Baeuerle, P A Baeuerle, 1992, Journal of virology.

Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa.

R. Knuechel, G. Rogler, J. Schölmerich, 1998, Gastroenterology.

A Subset of Human Dendritic Cells in the T Cell Area of Mucosa-Associated Lymphoid Tissue with a High Potential to Produce TNF-α1

G. Baretton, A. Greiner, P. Baeuerle, 2003, The Journal of Immunology.

Nuclear Factor Kb: An Oxidative Stress-Responsive Transcription Factor of Eukaryotic Cells (A Review)

K. Albermann, P. Baeuerle, P A Baeuerle, 1992 .

T cell leukemia-associated human Notch/translocation-associated Notch homologue has I kappa B-like activity and physically interacts with nuclear factor-kappa B proteins in T cells

J. Laborda, P. Baeuerle, M. Norcross, 1996, The Journal of experimental medicine.

Nuclear import-export: In search of signals and mechanisms

R. Lührmann, E. Nigg, P. Baeuerle, 1991, Cell.

Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-kappa B.

S. Ruben, M. Maher, C. H. Chen, 1991, Science.

IκB–NF-κB Structures At the Interface of Inflammation Control

P. Baeuerle, 1998, Cell.

IkappaB-NF-kappaB structures: at the interface of inflammation control.

P. Baeuerle, 1998, Cell.

Transcription factor NF-κB is activated in primary neurons by amyloid β peptides and in neurons surrounding early plaques from patients with Alzheimer disease

P. Baeuerle, B. Volk, C. Kaltschmidt, 1997 .

Transcription factor NF-κB is activated in microglia during experimental autoimmune encephalomyelitis

Christian Kaltschmidt, Barbara Kaltschmidt, Hartmut Wekerle, 1994, Journal of Neuroimmunology.

Constitutive NF-kappa B activity in neurons

H. Neumann, H. Wekerle, P. Baeuerle, 1994, Molecular and cellular biology.

Brain synapses contain inducible forms of the transcription factor NF-κB

P. Baeuerle, C. Kaltschmidt, B. Kaltschmidt, 1993, Mechanisms of Development.

[15]Identification of transcription factors and their target genes

H. Pahl, P. Baeuerle, 1996 .

Activation of transcription factor NF-kappaB by the adenovirus E3/19K protein requires its ER retention

H. Pahl, P. Baeuerle, M. Sester, 1996, The Journal of cell biology.

A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF‐kappa B.

H. Pahl, P. Baeuerle, 1995, The EMBO journal.

Tyrosine Phosphorylation of IκB-α Activates NF-κB without Proteolytic Degradation of IκB-α

C. Mueller-Dieckmann, P. Auberger, A. Livolsi, 1996, Cell.

A proteasome inhibitor prevents activation of NF‐kappa B and stabilizes a newly phosphorylated form of I kappa B‐alpha that is still bound to NF‐kappa B.

P. Baeuerle, E. Traenckner, S. Wilk, 1994, The EMBO journal.

Intramolecular masking of the nuclear location signal and dimerization domain in the precursor for the p50 NF-κB subunit

Thomas Henkel, Ellen Fanning, U. Zabel, 1992, Cell.

The rel-associated pp40 protein prevents DNA binding of Rel and NF-kappa B: relationship with I kappa B beta and regulation by phosphorylation.

I. Verma, H. Bose,, J. Inoue, 1991, Genes & development.

I kappa B: a specific inhibitor of the NF-kappa B transcription factor.

D. Baltimore, P. Baeuerle, P A Baeuerle, 1988, Science.

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor

D. Baltimore, P. Baeuerle, 1988, Cell.

Phorbol-ester-induced activation of the NF-kappa B transcription factor involves dissociation of an apparently cytoplasmic NF-kappa B/inhibitor complex.

D. Baltimore, M. Lenardo, P. Baeuerle, 1988, Cold Spring Harbor symposia on quantitative biology.

Transactivation domain 2 (TA2) of p65 NF-kappa B. Similarity to TA1 and phorbol ester-stimulated activity and phosphorylation in intact cells.

M. Schmitz, P. Baeuerle, M. A. Dos Santos Silva, 1995, The Journal of biological chemistry.

Selective Activation of NF-κB by Nerve Growth Factor Through the Neurotrophin Receptor p75

Y. Barde, P. Baeuerle, C. Kaltschmidt, 1996, Science.

Bcl-2 down-regulates the activity of transcription factor NF-kappaB induced upon apoptosis

S. Grimm, K. Schulze-Osthoff, P. Baeuerle, 1996, The Journal of cell biology.

Inducible Gene Expression, Volume 2

C. Molina, E. Lalli, N. Foulkes, 1995, Progress in Gene Expression.

Pro-inflammatory signaling: Last pieces in the NF-κB puzzle?

P. Baeuerle, 1998, Current Biology.

The IκB Kinase (IKK) Complex Is Tripartite and Contains IKKγ but Not IKAP as a Regular Component*

A. Klippel, C. Scheidereit, K. Giese, 2000, The Journal of Biological Chemistry.

Regulation of the transcription factors NF-kappa B and AP-1 by redox changes.

H. Pahl, P. Baeuerle, M. Meyer, 1994, Chemico-biological interactions.

Differential activation of transcription factors NF-kappa B and AP-1 in rat liver macrophages.

P. Baeuerle, K. Decker, T. Tran-Thi, 1995, Hepatology.

Blinatumomab: a historical perspective.

P. Kufer, P. Baeuerle, R. Bargou, 2012, Pharmacology & therapeutics.

Immunopharmacologic response of patients with B-lineage acute lymphoblastic leukemia to continuous infusion of T cell-engaging CD19/CD3-bispecific BiTE antibody blinatumomab.

Andreas Wolf, Dirk Nagorsen, Monika Brüggemann, 2012, Blood.

The proto-oncogene BCL-3 encodes an IκB protein

G. Nabel, I. Verma, C. Duckett, 1992 .

Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-kappaB activation.

P. Baeuerle, W. Henzel, C. Beraud, 1999, Proceedings of the National Academy of Sciences of the United States of America.

The p65 subunit is responsible for the strong transcription activating potential of NF‐kappa B.

P. Baeuerle, M.L. Schmitz, P.A. Baeuerle, 1991, The EMBO journal.

Nuclear signalling by tumour-associated antigen EpCAM

Brigitte Mack, Markus Munz, B. Mack, 2009, Nature Cell Biology.

Rapamycin attenuates vascular wall inflammation and progenitor cell promoters after angioplasty

V. Hombach, M. Rudelius, P. Baeuerle, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Highly Efficient Elimination of Colorectal Tumor-Initiating Cells by an EpCAM/CD3-Bispecific Antibody Engaging Human T Cells

M. Friedrich, P. Kufer, T. Raum, 2010, PloS one.

Constitutive nuclear NF-kappa B in cells of the monocyte lineage.

T. Sternsdorf, P. Baeuerle, B. Passlick, 1994, The Biochemical journal.

Expression and function of epithelial cell adhesion molecule EpCAM: where are we after 40 years?

O. Gires, P. Baeuerle, M. Canis, 2020, Cancer and Metastasis Reviews.

DNA binding of purified transcription factor NF-kappa B. Affinity, specificity, Zn2+ dependence, and differential half-site recognition.

U Zabel, U. Zabel, P. Baeuerle, 1991, The Journal of biological chemistry.

The emerging role of EpCAM in cancer and stem cell signaling.

Markus Munz, O. Gires, P. Baeuerle, 2009, Cancer research.

On the abundance of EpCAM on cancer stem cells

O. Gires, C. Klein, P. Baeuerle, 2009, Nature Reviews Cancer.

Long-term follow-up of hematologic relapse-free survival in a phase 2 study of blinatumomab in patients with MRD in B-lineage ALL.

H. Einsele, P. Kufer, P. Baeuerle, 2012, Blood.

Nuclear factor kB is activated by arachidonic acid but not by eicosapentaenoic acid.

P. Baeuerle, G. Poli, E. Chiarpotto, 1996, Biochemical and biophysical research communications.

Redox signalling by transcription factors NF-κB and AP-1 in lymphocytes

K. Schulze-Osthoff, P. Baeuerle, M. Los, 1995 .

IL‐2 gene expression and NF‐kappa B activation through CD28 requires reactive oxygen production by 5‐lipoxygenase.

K. Schulze-Osthoff, W. Dröge, P. Baeuerle, 1995, The EMBO journal.

A role for oxygen radicals as second messengers.

P. Baeuerle, P A Baeuerle, R Schreck, 1991, Trends in cell biology.

Interaction of the COOH-terminal Transactivation Domain of p65 NF-κB with TATA-binding Protein, Transcription Factor IIB, and Coactivators (*)

M. Meisterernst, M. Schmitz, P. Baeuerle, 1995, The Journal of Biological Chemistry.

Novel anti-denatured collagen humanized antibody D93 inhibits angiogenesis and tumor growth: An extracellular matrix-based therapeutic approach.

P. Baeuerle, D. V. Van Epps, J. Nickel, 2006, International journal of oncology.

Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease.

P. Baeuerle, B. Volk, C. Kaltschmidt, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Concentrations of EpCAM ectodomain as found in sera of cancer patients do not significantly impact redirected lysis and T-cell activation by EpCAM/CD3-bispecific BiTE antibody MT110

A. Wolf, O. Gires, P. Baeuerle, 2011, mAbs.

Expression of epithelial cellular adhesion molecule (Ep-CAM) in chronic (necro-)inflammatory liver diseases and hepatocellular carcinoma.

P. Schirmacher, M. Peters, P. Baeuerle, 2006, Hepatology research : the official journal of the Japan Society of Hepatology.

Epithelial tight junction proteins as potential antibody targets for pancarcinoma therapy

P. Kufer, S. Offner, P. Baeuerle, 2005, Cancer Immunology, Immunotherapy.

Transcriptome analysis reveals a role of interferon-gamma in human neointima formation.

F. Neumann, C. Klein, P. Baeuerle, 2001, Molecular cell.

trans-Activation of the HIV type 1 promoter by 7,8-dihydroneopterin in vitro.

E. Werner, D. Fuchs, G. Baier, 1997, AIDS research and human retroviruses.

Hypoxia Induces c-fos Transcription via a Mitogen-activated Protein Kinase-dependent Pathway*

P. Baeuerle, R. Rupec, Judith M. Müller, 1997, The Journal of Biological Chemistry.

Efficient elimination of chronic lymphocytic leukaemia B cells by autologous T cells with a bispecific anti-CD19/anti-CD3 single-chain antibody construct

B. Dörken, P. Kufer, C. Wuchter, 2003, Leukemia.

Gene Expression Profiling of Human Stent-Induced Neointima by cDNA Array Analysis of Microscopic Specimens Retrieved by Helix Cutter Atherectomy: Detection of FK506-Binding Protein 12 Upregulation

F. Neumann, A. Schömig, C. Klein, 2001, Circulation.

Transcriptome analysis reveals a role of interferon-gamma in human neointima formation.

C. Klein, P. Baeuerle, R. Wessely, 2001, Molecular cell.

Targeted therapy with the T-cell-engaging antibody blinatumomab of chemotherapy-refractory minimal residual disease in B-lineage acute lymphoblastic leukemia patients results in high response rate and prolonged leukemia-free survival.

Hermann Einsele, Carsten Reinhardt, Thomas Burmeister, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Myocardial gene expression of matched hibernating and control tissue from patients with ischemic left ventricular dysfunction

M. Schwaiger, A. Schömig, F. Bengel, 2008, Heart and Vessels.

Dysregulation of Monocytic Nuclear Factor-κB by Oxidized Low-Density Lipoprotein

F. Neumann, N. Mackman, P. Baeuerle, 1997 .

IKAP is a scaffold protein of the IκB kinase complex

P. Baeuerle, W. Henzel, Patrick A. Baeuerle, 1998, Nature.

Role of nuclear factor‐kappa B in atherogenesis

P. Baeuerle, K. Brand, D. Neumeier, 1997, Experimental physiology.

Chapter 23 - Kinases in Pro-Inflammatory Signal Transduction Pathways: New Opportunities for Drug Discovery

P. Baeuerle, V. Baichwal, 1998 .

Abstract 5626: Single-chain bispecific BiTE antibody specific for CD3 and melanoma-associated chondroitin sulfate proteoglycan: In vitro and in vivo anti-melanoma activity

D. Morton, P. Kufer, P. Baeuerle, 2010 .

Abstract #3252: Effector memory T cells make a major contribution to redirected target cell lysis by T cell-engaging BiTE antibody MT110

R. Kischel, P. Kufer, P. Baeuerle, 2009 .

T Cell Costimulus-Independent and Very Efficacious Inhibition of Tumor Growth in Mice Bearing Subcutaneous or Leukemic Human B Cell Lymphoma Xenografts by a CD19-/CD3- Bispecific Single-Chain Antibody Construct1

Iduna Fichtner, P. Kufer, I. Fichtner, 2003, The Journal of Immunology.

Rapamycin effects transcriptional programs in smooth muscle cells controlling proliferative and inflammatory properties.

F. Neumann, A. Schömig, P. Baeuerle, 2004, Molecular pharmacology.

EpCAM/CD3-Bispecific T-cell Engaging Antibody MT110 Eliminates Primary Human Pancreatic Cancer Stem Cells

C. Heeschen, P. Baeuerle, M. Cioffi, 2011, Clinical Cancer Research.

EpCAM (CD326) finding its role in cancer

O. Gires, P. Baeuerle, P A Baeuerle, 2007, British Journal of Cancer.

Expression of the types A and B tumor necrosis factor (TNF) receptors is independently regulated, and both receptors mediate activation of the transcription factor NF-kappa B. TNF alpha is not needed for induction of a biological effect via TNF receptors.

P. Baeuerle, H. Hohmann, M. Brockhaus, 1990, The Journal of biological chemistry.

T-cell-engaging antibodies for the treatment of solid tumors: challenges and opportunities

P. Baeuerle, H. Wesche, 2022, Current opinion in oncology.

A novel IgG-based FLT3xCD3 bispecific antibody for the treatment of AML and B-ALL

P. Baeuerle, H. Salih, J. Michaelson, 2022, Journal for ImmunoTherapy of Cancer.

Mesothelin-targeting T cells bearing a novel T cell receptor fusion construct (TRuC) exhibit potent antitumor efficacy against solid tumors

Guangwu Guo, P. Baeuerle, Greg M. Delgoffe, 2023, Oncoimmunology.

Preclinical Characterization of AMG 330, a CD3/CD33-Bispecific T-Cell–Engaging Antibody with Potential for Treatment of Acute Myelogenous Leukemia

A. Henn, M. Friedrich, P. Hoffmann, 2014, Molecular Cancer Therapeutics.

Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-kappa B.

S. Ruben, M. Maher, C. H. Chen, 1991, Science.

High concentrations of therapeutic IgG1 antibodies are needed to compensate for inhibition of antibody-dependent cellular cytotoxicity by excess endogenous immunoglobulin G.

A. Wolf, P. Baeuerle, A. D. da Silva, 2006, Molecular immunology.

Exchanging human Fcγ1 with murine Fcγ2a highly potentiates anti-tumor activity of anti-EpCAM antibody adecatumumab in a syngeneic mouse lung metastasis model

P. Baeuerle, R. Hofmeister, B. Schlereth, 2007, Cancer Immunology, Immunotherapy.

Cellular and complement-dependent cytotoxicity of Ep-CAM-specific monoclonal antibody MT201 against breast cancer cell lines

M. Peters, P. Baeuerle, P A Baeuerle, 2005, British Journal of Cancer.

A phase I study with adecatumumab, a human antibody directed against epithelial cell adhesion molecule, in hormone refractory prostate cancer patients.

T. Raum, P. Baeuerle, D. Weckermann, 2006, European journal of cancer.

Combination of rituximab with blinatumomab (MT103/MEDI-538), a T cell-engaging CD19-/CD3-bispecific antibody, for highly efficient lysis of human B lymphoma cells.

P. Kufer, R. Lutterbuese, P. Kiener, 2009, Leukemia research.

Sustained Response Duration Seen after Treatment with Single Agent Blinatumomab (MT103/MEDI-538) in the Ongoing Phase I Study MT103- 104 in Patients with Relapsed NHL

H. Einsele, P. Kufer, P. Baeuerle, 2008 .

Therapeutic window of MuS110, a single-chain antibody construct bispecific for murine EpCAM and murine CD3.

R. Kischel, P. Kufer, R. Lutterbuese, 2008, Cancer research.

Bispecific antibodies for polyclonal T-cell engagement.

P. Kufer, P. Baeuerle, R. Lutterbüse, 2003, Current opinion in molecular therapeutics.

The 65-kD subunit of NF-kappa B is a receptor for I kappa B and a modulator of DNA-binding specificity.

P. Baeuerle, M. B. Urban, 1990, Genes & development.

A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.

D. Baltimore, P. Baeuerle, 1989, Genes & development.

Antitumor Activity of an EpCAM/CD3-bispecific BiTE Antibody During Long-term Treatment of Mice in the Absence of T-cell Anergy and Sustained Cytokine Release

M. Friedrich, R. Kischel, P. Kufer, 2009, Journal of immunotherapy.

Control of gene expression by proteolysis.

H. Pahl, P. Baeuerle, P A Baeuerle, 1996, Current opinion in cell biology.

The primary structure of human secretogranin I (chromogranin B): comparison with chromogranin A reveals homologous terminal domains and a large intervening variable region.

J. Mallet, W. Huttner, A. Lamouroux, 1987, The EMBO journal.

Synthetic TRuC receptors engaging the complete T cell receptor for potent anti-tumor response

S. Weiler, Jian Ding, W. Schamel, 2019, Nature Communications.

Side-by-side analysis of five clinically tested anti-EpCAM monoclonal antibodies

J. Fagerberg, P. Kufer, T. Raum, 2010, Cancer Cell International.

Tyrosine Phosphorylation of IkB-a Activates NF-kB without Proteolytic Degradation of IkB-a

C. Mueller-Dieckmann, P. Auberger, A. Livolsi, 1996 .

Proteins controlling the nuclear uptake of NF-κB, Rel and dorsal

M. Schmitz, P. Baeuerle, T. Henkel, 1991 .

Regulation ofTumorNecrosis Factor AlphaTranscription in Macrophages: Involvement ofFourKB-Like Motifs andof Constitutive andInducible FormsofNF-KB

P. Baeuerle, P. Vassalli, M. Collart, 1990 .

A new interference footprinting method for analysing simultaneously protein contacts to phosphate and guanine residues on DNA.

P. Baeuerle, H. Büning, H. Zorbas, 1995, Nucleic acids research.

Transactivation Domain 2 (TA2) of p65 NF-κB

M. Schmitz, P. Baeuerle, M. S. Silva, 1995, The Journal of Biological Chemistry.

Construct Bispecific for Murine EpCAM and Murine CD 3 Therapeutic Window of MuS 110 , a Single-Chain Antibody

R. Kischel, P. Kufer, R. Lutterbuese, 2007 .

Therapeutic Window of MuS 110 , a Single-Chain Antibody Construct Bispecific for Murine EpCAM and Murine CD 3

R. Kischel, P. Kufer, R. Lutterbuese, 2007 .

Assessing oxygen radicals as mediators in activation of inducible eukaryotic transcription factor NF-kappa B.

P. Baeuerle, R. Schreck, 1994, Methods in enzymology.

Dithiocarbamates as Potent Inhibitors of Nuclear Factor KB Activation in Intact Cells By galf Schreck, Beate Meier,* Daniela N. M~innel,~ Wulf Dr6ge,~

P. Baeuerle, 1992 .

Regression of Human Prostate Cancer Xenografts in Mice by AMG 212/BAY2010112, a Novel PSMA/CD3-Bispecific BiTE Antibody Cross-Reactive with Non-Human Primate Antigens

M. Friedrich, P. Hoffmann, R. Kischel, 2012, Molecular Cancer Therapeutics.

Structural and functional analysis of the NF-kappa B p65 C terminus. An acidic and modular transactivation domain with the potential to adopt an alpha-helical conformation.

M. Czisch, T. Holak, M. Schmitz, 1994, The Journal of biological chemistry.

Purification of yolk protein 2 of Drosophila melanogaster and identification of its site of tyrosine sulfation.

W. Huttner, F. Lottspeich, P. Baeuerle, 1988, The Journal of biological chemistry.

NF-kappa B activation in human knee-joint synovial tissue during the early stage of joint inflammation.

P. Baeuerle, C. Kaltschmidt, C. Morris, 1997, Biochemical Society transactions.

Potential involvement of the transcription factor NF-κB in neurological disorders

P. Baeuerle, C. Kaltschmidt, B. Kaltschmidt, 1993 .

Pro-inflammatory signaling: last pieces in the NF-kappaB puzzle?

P. Baeuerle, 1998, Current biology : CB.

Multi-Step Activation of NF-κB/Rel Transcription Factors

M. Schmitz, P. Baeuerle, 1995 .

Lipopolysaccharide-induced lung inflammation is inhibited by neutralization of GM-CSF.

P. Baeuerle, K. Brune, A. Pahl, 2007, European journal of pharmacology.

Activation of NF-kB by nerve growth factor through the neurotrophin receptor p75

Y. Barde, P. Baeuerle, C. Kaltschmidt, 1996 .

Engaging natural killer cells for cancer therapy via NKG2D, CD16A and other receptors

P. Baeuerle, J. Michaelson, K. Rakhra, 2023, mAbs.

Signal Transduction from the Cytoplasm to the Cell Nucleus by NF-κB/Rel Transcription Factors

M. Schmitz, P. Baeuerle, 1995 .

Report of a Phase II Trial of Single-Agent BiTE® Antibody Blinatumomab in Patients with Minimal Residual Disease (MRD) Positive B-Precursor Acute Lymphoblastic Leukemia (ALL).

H. Einsele, P. Kufer, P. Baeuerle, 2009 .

IKAP is a scaffold protein of the IkappaB kinase complex.

L Cohen, P. Baeuerle, W. Henzel, 1998, Nature.

Potent inhibition of local and disseminated tumor growth in immunocompetent mouse models by a bispecific antibody construct specific for Murine CD3

R. Kischel, P. Kufer, I. Fichtner, 2006, Cancer Immunology, Immunotherapy.

Redox signalling by transcription factors NF-kappa B and AP-1 in lymphocytes.

K. Schulze-Osthoff, P. Baeuerle, M. Los, 1995, Biochemical pharmacology.

study of blinatumomab in patients with MRD in B-lineage ALL Long-term follow-up of hematologic relapse-free survival in a phase 2

H. Einsele, P. Kufer, P. Baeuerle, 2012 .

KBF1 (p50 NF-kappa B homodimer) acts as a repressor of H-2Kb gene expression in metastatic tumor cells

P. Baeuerle, L. Eisenbach, D. Plaksin, 1993, The Journal of experimental medicine.

Nuclear factor kappa B: an oxidative stress-responsive transcription factor of eukaryotic cells (a review).

K. Albermann, P. Baeuerle, R. Schreck, 1992, Free radical research communications.

8 - Reactive Oxygen Species as Costimulatory Signals of Cytokine-Induced NF- k B Activation Pathways

P. Baeuerle, 2000 .

Cancer Therapy : Preclinical EpCAM / CD 3-Bispeci fi c T-cell Engaging Antibody MT 110 Eliminates Primary Human Pancreatic Cancer Stem Cells

C. Heeschen, P. Baeuerle, J. Dorado, 2012 .

Pharmacokinetic and Pharmacodynamic Relationship of Blinatumomab in Patients with Non-Hodgkin Lymphoma

P. Kufer, A. Wolf, P. Baeuerle, 2018, Current Clinical Pharmacology.

Purified human I kappa B can rapidly dissociate the complex of the NF-kappa B transcription factor with its cognate DNA.

U. Zabel, P. Baeuerle, 1990, Cell.

CLN-978, a novel half-life extended CD19/CD3/HSA-specific T cell-engaging antibody construct with potent activity against B-cell malignancies with low CD19 expression

P. Baeuerle, J. Michaelson, Bochong Li, 2023, Journal for ImmunoTherapy of Cancer.

Cancer Therapy: Preclinical EpCAM/CD3-Bispecific T-cell Engaging Antibody MT110 Eliminates Primary Human Pancreatic Cancer Stem Cells

C. Heeschen, P. Baeuerle, J. Dorado, 2012 .

Bispecific T-cell engaging antibodies for cancer therapy.

P. Baeuerle, C. Reinhardt, 2009, Cancer research.

Antiviral Activity of HIV gp120-Targeting Bispecific T Cell Engager Antibody Constructs

P. Kufer, M. Muenz, T. Raum, 2018, Journal of Virology.

T cell leukemia-associated human Notch/translocation-associated Notch homologue has I kappa B-like activity and physically interacts with nuclear factor-kappa B proteins in T cells

J. Laborda, P. Baeuerle, M. Norcross, 1996, The Journal of experimental medicine.

The emerging role of EpCAM in cancer and stem cell signaling.

O. Gires, P. Baeuerle, Markus Munz, 2009, Cancer research.

Nuclear signalling by tumour-associated antigen EpCAM

B. Mack, O. Gires, P. Went, 2009, Nature Cell Biology.

Enter a polypeptide messenger

P. Baeuerle, 1995, Nature.

Recombinant Antibody Fusion Proteins for Depletion of Autoreactive B Lymphocytes

H. Schnitzler, P. Baeuerle, S. Zocher, 2002 .

NF-kappa B activation in human knee-joint synovial tissue during the early stage of joint inflammation.

P. Baeuerle, C. Kaltschmidt, C. Morris, 1997, Biochemical Society transactions.

Constitutive nuclear NF-KB in cells of the monocyte lineage

T. Sternsdorf, B. Passlick, P. Baeuerle, 2005 .

Immunotherapy of lymphoma and leukemia with T-cell engaging BiTE antibody blinatumomab

P. Kufer, P. Baeuerle, G. Zugmaier, 2009, Leukemia & lymphoma.

A vector, pHisGal, allowing bacterial production of proteins fused to a hexahistidine-tagged Gal4 DNA-binding domain.

M. Schmitz, P. Baeuerle, 1994, BioTechniques.

Abstract 3526: Subcutaneous administration of PSMA/CD3-bispecific BiTE antibody MT112/BAY 2010112 leads to complete remission of human prostate cancer xenografts in mice

M. Friedrich, P. Kufer, B. Rattel, 2012 .

Abstract #3248: Anti-tumor activity of a T cell-engaging MCSP-specific BiTE antibody at very low effector to target ratios: A new approach to treat metastatic melanoma

D. Morton, P. Kufer, R. Lutterbuese, 2009 .

Pharmacokinetic and Pharmacodynamic Relationship of Blinatumomab in Patients with Non-Hodgkin Lymphoma

P. Kufer, A. Wolf, P. Baeuerle, 2018, Current clinical pharmacology.

Abstract 2078: CLN-049 is a bispecific T cell engaging IgG-like antibody targeting FLT3 on AML cells

P. Baeuerle, J. Michaelson, Bochong Li, 2022, Cancer Research.

Inhibition ofN-glycosylation induces tyrosine sulphation ofhybridoma immunoglobulin G

P. Baeuerle, B. Huttner, 1984 .

Environmental stresses and nutrients

P. Baeuerle, 1995 .

The interleukin-2 antagonizing antibody MT204 delays allogeneic skin graft rejection in non-human primates and is well tolerated.

B. Rattel, P. Baeuerle, T. Boehm, 2011, Transplant immunology.

Cellular and complement-dependent cytotoxicity of Ep-CAM-specific monoclonal antibody MT201 against breast cancer cell lines

M. Peters, P. Baeuerle, K. Brischwein, 2005, British Journal of Cancer.