J. Kikuchi

发表

Lineage‐specific regulation of cell cycle control gene expression during haematopoietic cell differentiation

Y. Furukawa, J. Kikuchi, Mitsuru Nakamura, 2000, British journal of haematology.

Epigenetic mechanisms of cell adhesion-mediated drug resistance in multiple myeloma

Y. Furukawa, J. Kikuchi, 2016, International Journal of Hematology.

Myeloma Cells Are Activated in Bone Marrow Microenvironment by the CD180/MD-1 Complex, Which Senses Lipopolysaccharide.

Y. Furukawa, J. Kikuchi, Y. Kuroda, 2018, Cancer research.

Bortezomib overcomes cell adhesion-mediated drug resistance through downregulation of VLA-4 expression in multiple myeloma

Y. Furukawa, K. Ozawa, M. Mori, 2009, Oncogene.

Romidepsin Overcomes Cell Adhesion-Mediated Drug Resistance in Multiple Myeloma Cells

Y. Furukawa, K. Ozawa, T. Nagai, 2013, Acta Haematologica.

Phosphorylation-mediated EZH2 inactivation promotes drug resistance in multiple myeloma

Y. Furukawa, J. Kikuchi, B. Bogen, 2015 .

Fast in-vitro screening of FLT3-ITD inhibitors using silkworm-baculovirus protein expression system

N. Shibayama, Y. Furukawa, J. Kikuchi, 2021, bioRxiv.

Sustained transgene expression by human cord blood derived CD34+ cells transduced with simian immunodeficiency virus agmTYO1‐based vectors carrying the human coagulation factor VIII gene in NOD/SCID mice

A. Ishiwata, S. Madoiwa, J. Mimuro, 2004, The journal of gene medicine.

AMP‐activated protein kinase activation primes cytoplasmic translocation and autophagic degradation of the BCR‐ABL protein in CML cells

Y. Furukawa, J. Kikuchi, Y. Kuroda, 2020, Cancer science.

Recombinant adeno-associated virus vector-transduced vascular endothelial cells express the thrombomodulin transgene under the regulation of enhanced plasminogen activator inhibitor-1 promoter

S. Madoiwa, J. Mimuro, Y. Sakata, 2001, Gene Therapy.

Specific Antileukemic Activity of PD0332991, a CDK4/6 Inhibitor, against Philadelphia Chromosome–Positive Lymphoid Leukemia

K. Goi, S. Kimura, Y. Furukawa, 2015, Molecular Cancer Therapeutics.

BCR-ABL regulates death receptor expression for TNF-related apoptosis-inducing ligand (TRAIL) in Philadelphia chromosome-positive leukemia

K. Goi, Y. Furukawa, J. Kikuchi, 2013, Oncogene.

Inactivation of the Retinoblastoma Protein by Mutant B-Raf in Malignant Melanoma

Y. Furukawa, M. Ohtsuki, J. Kikuchi, 2010 .

Up-regulation of Survivin by the E2A-HLF Chimera Is Indispensable for the Survival of t(17;19)-positive Leukemia Cells*

A. Look, R. Altura, T. Inaba, 2009, The Journal of Biological Chemistry.

CD43, but not P-selectin glycoprotein ligand-1, functions as an E-selectin counter-receptor in human pre-B-cell leukemia NALL-1.

R. Kannagi, Y. Furukawa, J. Kikuchi, 2008, Cancer research.

Polyploidization and functional maturation are two distinct processes during megakaryocytic differentiation: involvement of cyclin-dependent kinase inhibitor p21 in polyploidization.

M. Kitagawa, Y. Furukawa, N. Komatsu, 1997, Blood.

Transfection of antisense core 2 β1,6-N-acetylglucosaminyltransferase-1 cDNA suppresses selectin ligand expression and tissue infiltration of B-cell precursor leukemia cells

J. Kikuchi, M. Nakamura, H. Nojiri, 2005, Leukemia.

Transactivation of RON receptor tyrosine kinase by interaction with PDGF receptor beta during steady-state growth of human mesangial cells.

Y. Furukawa, J. Kikuchi, S. Muto, 2009, Kidney International.

Expression of human coagulation factor VIII in adipocytes transduced with the simian immunodeficiency virus agmTYO1-based vector for hemophilia A gene therapy

S. Madoiwa, J. Mimuro, Y. Sakata, 2004, Gene Therapy.

Apoptosis during HL‐60 cell differentiation is closely related to a G0/G1 cell cycle arrest

Y. Furukawa, J. Kikuchi, M. Saito, 1995, Journal of cellular physiology.

Alkylating agents induce histone H3K18 hyperacetylation and potentiate HDAC inhibitor-mediated global histone acetylation and cytotoxicity in mantle cell lymphoma

Y. Furukawa, J. Kikuchi, D. Koyama, 2013, Blood Cancer Journal.

A simple semisolid subtraction method using carbodiimide-coated microplates

Osamu Suzuki, Y. Furukawa, J. Kikuchi, 2000, Molecular biotechnology.

E2F‐6 Suppresses Growth‐Associated Apoptosis of Human Hematopoietic Progenitor Cells by Counteracting Proapoptotic Activity of E2F‐1

Y. Furukawa, K. Ozawa, J. Kikuchi, 2007, Stem cells.

Eradication of Central Nervous System Leukemia of T-Cell Origin with a Brain-Permeable LSD1 Inhibitor

T. Umehara, Y. Furukawa, J. Kikuchi, 2018, Clinical Cancer Research.

Preferential Production of Interleukin‐1β over Interleukin‐1 Receptor Antagonist Contributes to Proliferation and Suppression of Apoptosis in Leukemic Cells

Y. Furukawa, Y. Miura, J. Kikuchi, 1995, Japanese journal of cancer research : Gann.

Transcriptional Activation of the cdc2 Gene Is Associated with Fas-induced Apoptosis of Human Hematopoietic Cells*

M. Kitagawa, Y. Furukawa, J. Kikuchi, 1996, The Journal of Biological Chemistry.

Soluble SLAMF7 promotes the growth of myeloma cells via homophilic interaction with surface SLAMF7

Y. Furukawa, J. Kikuchi, Y. Kuroda, 2019, Leukemia.

Multiple Myeloma: bench to bedside.

Y. Furukawa, J. Kikuchi, Y. Kuroda, 2017 .

Defective Sorting to Secretory Vesicles in Trans-Golgi Network Is Partly Responsible for Protein C Deficiency: Molecular Mechanisms of Impaired Secretion of Abnormal Protein C R169W, R352W, and G376D

H. Endo, S. Madoiwa, J. Mimuro, 2003, Circulation research.

Defective Sorting to Secretory Vesicles in Trans-Golgi Network Is Partly Responsible for Protein C Deficiency Molecular Mechanisms of Impaired Secretion of Abnormal Protein C R 169

H. Endo, S. Madoiwa, J. Mimuro, 2003 .

Transcriptional repression of the E2F-1 gene by interferon-α is mediated through induction of E2F-4/pRB and E2F-4/p130 complexes

Y. Furukawa, J. Kikuchi, Mitsuru Nakamura, 1999, Oncogene.

Bone marrow stromal cell-mediated degradation of CD20 leads to primary rituximab resistance in mantle cell lymphoma

Y. Furukawa, J. Kikuchi, S. Ito, 2020, Leukemia.

Preferential expression of phosphatidylglucoside along neutrophil differentiation pathway

K. Ozawa, T. Hanafusa, J. Kikuchi, 2009, Leukemia & lymphoma.

Identification of Novel p 53-Binding Proteins by Biomolecular Interaction Analysis Combined with Tandem Mass Spectrometry

Y. Furukawa, J. Kikuchi, N. Hayashi, 2022 .

Anti-leukemic activity of bortezomib and carfilzomib on B-cell precursor ALL cell lines

Hiroki Sato, K. Goi, Y. Furukawa, 2017, PloS one.

Cell-cycle-dependent regulation of erythropoietin receptor gene.

Y. Furukawa, K. Kirito, N. Komatsu, 1997, Blood.

MSK1 activation in acute myeloid leukemia cells with FLT3 mutations

Y. Furukawa, J. Kikuchi, R. Shimizu, 2010, Leukemia.

Latexin regulates the abundance of multiple cellular proteins in hematopoietic stem cells

Y. Furukawa, J. Kikuchi, T. Wada, 2012, Journal of cellular physiology.

Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma.

Y. Furukawa, K. Ozawa, J. Kikuchi, 2010, Blood.

Single Glycosyltransferase, Core 2 β1→6-N-acetylglucosaminyltransferase, Regulates Cell Surface Sialyl-Lex Expression Level in Human Pre-B Lymphocytic Leukemia Cell Line KM3 Treated with Phorbolester*

Y. Furukawa, J. Kikuchi, Mitsuru Nakamura, 1998, The Journal of Biological Chemistry.

Not core 2 beta 1,6-N-acetylglucosaminyltransferase-2 or -3 but -1 regulates sialyl-Lewis x expression in human precursor B cells.

J. Kikuchi, Mitsuru Nakamura, H. Nojiri, 2004, Glycobiology.

Induction of ubiquitin-conjugating enzyme by aggregated low density lipoprotein in human macrophages and its implications for atherosclerosis.

Y. Furukawa, I. Sakurabayashi, J. Kikuchi, 2000, Arteriosclerosis, thrombosis, and vascular biology.

Phosphorylation of Bcl-2 Protein by CDC2 Kinase during G2/M Phases and Its Role in Cell Cycle Regulation*

Y. Furukawa, J. Kikuchi, Mitsuru Nakamura, 2000, The Journal of Biological Chemistry.

Histone deacetylase 1 enhances microRNA processing via deacetylation of DGCR8

Y. Furukawa, J. Kikuchi, T. Wada, 2012, EMBO reports.

Molecular basis of clonal evolution in multiple myeloma

Y. Furukawa, J. Kikuchi, 2020, International Journal of Hematology.

Molecular pathogenesis of multiple myeloma

Y. Furukawa, J. Kikuchi, 2015, International Journal of Clinical Oncology.

Aberrant induction of LMO2 by the E2A-HLF chimeric transcription factor and its implication in leukemogenesis of B-precursor ALL with t(17;19).

A. Look, B. Göttgens, T. Inaba, 2010, Blood.

HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias

A. Joshi, J. Landry, F. Calero-Nieto, 2013, Oncogene.

Arf tumor suppressor disrupts the oncogenic positive feedback loop including c-Myc and DDX5

Y. Furukawa, J. Kikuchi, K. Suzuki, 2014, Oncogene.

Promoter methylation confers kidney‐specific expression of the Klotho gene

Y. Furukawa, M. Kuro-o, J. Kikuchi, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

β2-Microglobulin Identified as an Apoptosis-Inducing Factor and Its Characterization

H. Mano, Y. Furukawa, S. Shimamura, 1999 .

Identified as an Apoptosis-Inducing Factor and Its Characterization

H. Mano, Y. Furukawa, S. Shimamura, 1999 .

Phosphorylation-mediated EZH 2 inactivation promotes drug resistance in multiple myeloma

Y. Furukawa, J. Kikuchi, B. Bogen, 2018 .

Phosphorylation-mediated EZH2 inactivation promotes drug resistance in multiple myeloma.

Y. Furukawa, J. Kikuchi, B. Bogen, 2015, The Journal of clinical investigation.

Bcl-x is a regulatory factor of apoptosis and differentiation in megakaryocytic lineage cells.

Y. Furukawa, Y. Miura, J. Kikuchi, 1998, Experimental hematology.

A novel variant of acute myelomonocytic leukemia carrying t(3;12)(q26;p13) with characteristics of 3q21q26 syndrome.

H. Yamada, Y. Furukawa, J. Kikuchi, 1998, International journal of hematology.

The Novel Orally Active Proteasome Inhibitor K-7174 Exerts Anti-myeloma Activity in Vitro and in Vivo by Down-regulating the Expression of Class I Histone Deacetylases*

Y. Furukawa, J. Kikuchi, D. Koyama, 2013, The Journal of Biological Chemistry.

Homopiperazine Derivatives as a Novel Class of Proteasome Inhibitors with a Unique Mode of Proteasome Binding

N. Shibayama, Sam-Yong Park, Y. Furukawa, 2013, PloS one.

Overexpression of the shortest isoform of histone demethylase LSD1 primes hematopoietic stem cells for malignant transformation.

Y. Furukawa, J. Kikuchi, H. Honda, 2015, Blood.

Defective binding of IRFs to the initiator element of interleukin‐1β‐converting enzyme (ICE) promoter in an interferon‐resistant Daudi subline

Y. Furukawa, J. Kikuchi, Mitsuru Nakamura, 1999, FEBS letters.

Proteasome inhibitors exert cytotoxicity and increase chemosensitivity via transcriptional repression of Notch1 in T-cell acute lymphoblastic leukemia

Y. Furukawa, J. Kikuchi, S. Chiba, 2013, Leukemia.

Modulation of E2F Activity Is Linked to Interferon-induced Growth Suppression of Hematopoietic Cells*

Y. Furukawa, J. Kikuchi, Mitsuru Nakamura, 1997, The Journal of Biological Chemistry.

HDAC inhibitors augment cytotoxic activity of rituximab by upregulating CD20 expression on lymphoma cells

Y. Furukawa, K. Ozawa, J. Kikuchi, 2010, Leukemia.

Identification of novel p53-binding proteins by biomolecular interaction analysis combined with tandem mass spectrometry

Jiro Kikuchi, Y. Furukawa, J. Kikuchi, 2003, Molecular biotechnology.

Purine Analog-Like Properties of Bendamustine Underlie Rapid Activation of DNA Damage Response and Synergistic Effects with Pyrimidine Analogues in Lymphoid Malignancies

Y. Furukawa, T. Yamauchi, J. Kikuchi, 2014, PloS one.

Simultaneous core 2 β1→6N‐acetylglucosaminyltransferase up‐regulation and sialyl‐LeX expression during activation of human tonsillar B lymphocytes

Y. Furukawa, J. Kikuchi, Mitsuru Nakamura, 1999, FEBS letters.

UDP-GlcNAc:Galbeta1-->3GalNAc (GlcNAc to GalNAc) beta1-->6N-acetylglucosaminyltransferase holds a key role on the control of CD15s expression in human pre-B lymphoid cell lines.

Y. Furukawa, J. Kikuchi, Mitsuru Nakamura, 1999, Glycobiology.

EMD originates from hyaluronan-induced homophilic interactions of CD44 variant-expressing MM cells under shear stress

Y. Furukawa, N. Takahashi, J. Kikuchi, 2022, Blood advances.

Lysine-specific demethylase 1 inhibitors prevent teratoma development from human induced pluripotent stem cells

T. Umehara, Y. Furukawa, J. Kikuchi, 2018, Oncotarget.

Overexpression of the shortest isoform of histone demethylase LSD1 primes hematopoietic stem/progenitor cells for malignant transformation

Y. Furukawa, J. Kikuchi, H. Honda, 2015 .

A novel missense mutation of ABCA1 in transmembrane alpha-helix in a Japanese patient with Tangier disease.

K. Kotani, Y. Furukawa, Mizuho Maekawa, 2009, Atherosclerosis.

Regulatory effects of aggregated LDL on apoptosis during foam cell formation of human peripheral blood monocytes

Y. Furukawa, I. Sakurabayashi, J. Kikuchi, 1997, FEBS letters.

Expression Levels of Histone Deacetylases Determine the Cell Fate of Hematopoietic Progenitors*

Y. Furukawa, N. Nishimura, T. Kitamura, 2009, The Journal of Biological Chemistry.

The FLT3 inhibitor PKC412 exerts differential cell cycle effects on leukemic cells depending on the presence of FLT3 mutations

Y. Furukawa, J. Kikuchi, R. Shimizu, 2008, Oncogene.

Suitable drug combination with bortezomib for multiple myeloma under stroma-free conditions and in contact with fibronectin or bone marrow stromal cells

Y. Furukawa, J. Kikuchi, D. Koyama, 2014, International Journal of Hematology.

Beta(2)-microglobulin identified as an apoptosis-inducing factor and its characterization.

H. Mano, Y. Furukawa, S. Shimamura, 1999, Blood.

Conversion of human fibroblasts into multipotent cells by cell-penetrating peptides.

Y. Furukawa, J. Kikuchi, N. Osada, 2019, Biochemical and biophysical research communications.

Kinetics of cytokine receptor internalization under steady-state conditions affects growth of neighboring blood cells

T. Inaba, Y. Furukawa, J. Kikuchi, 2020, Haematologica.

Regulation of macrophage‐specific gene expression by degenerated lipoproteins

Y. Furukawa, I. Sakurabayashi, J. Kikuchi, 2000, Electrophoresis.

[Mechanisms of action and clinical effectiveness of the newly approved anti-cancer drug bendamustine].

Y. Furukawa, J. Kikuchi, T. Wada, 2011, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

mTOR inhibitors sensitize multiple myeloma cells to venetoclax via IKZF3- and Blimp-1-mediated BCL-2 upregulation

Y. Furukawa, J. Leverson, J. Kikuchi, 2021, Haematologica.

c‐FOS is an integral component of the IKZF1 transactivator complex and mediates lenalidomide resistance in multiple myeloma

Y. Furukawa, N. Takahashi, J. Kikuchi, 2023, Clinical and translational medicine.

Up-regulation of VLA-5 expression during monocytic differentiation and its role in negative control of the survival of peripheral blood monocytes.

Y. Furukawa, J. Kikuchi, Y. Kanakura, 1996, Journal of immunology.