H. Esche

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E1A is sufficient by itself to induce apoptosis independent of p53 and other adenoviral gene products

T. Stiewe, B. Pützer, K. Parssanedjad, 2000, Cell Death and Differentiation.

Cellular uptake and toxicity of Au55 clusters.

W. Brandau, H. Esche, G. Schmid, 2005, Small.

E1A overcomes the apoptosis block in BCR-ABL+ leukemia cells and renders cells susceptible to induction of apoptosis by chemotherapeutic agents.

B. Pützer, T. Stiewe, K. Parssanedjad, 2000, Cancer research.

Improved safety through tamoxifen-regulated induction of cytotoxic genes delivered by Ad vectors for cancer gene therapy

T. Stiewe, B. Pützer, H. Esche, 2000, Gene Therapy.

The E1A N terminus (aa 1-29) of the highly oncogenic adenovirus type 12 harbours a trans-activation function not detectable in the non-oncogenic serotype 2.

H. Esche, G. Kroener-Lux, K. Lipinski, 1997, The Journal of general virology.

The multifunctional role of E1A in the transcriptional regulation of CREB/CBP-dependent target genes.

H. Esche, D. Brockmann, 2003, Current topics in microbiology and immunology.

The histone acetyltransferase activity of PCAF cooperates with the brahma/SWI2-related protein BRG-1 in the activation of the enhancer A of the MHC class I promoter.

H. Esche, U. Schmücker, D. Brockmann, 2001, Gene.

Binding of PKA-RIIalpha to the Adenovirus E1A12S oncoprotein correlates with its nuclear translocation and an increase in PKA-dependent promoter activity.

C. Carlson, P. Collas, K. Taskén, 2001, Virology.

Adenoviridae: second report.

H. Esche, H. Ginsberg, G. Wadell, 1982, Intervirology.

A Point Mutation in the First Splice Donor Leads to Reduced Oncogenic Properties of the Adenovirus Serotype 12 E1A Gene

H. Esche, D. Brockmann, O. Lehmkühler, 2003, Intervirology.

Amino acids 1-29 of the adenovirus serotypes 12 and 2 E1A proteins interact with rap30 (TF(II)F) and TBP in vitro.

H. Esche, K. Lipinski, D. Brockmann, 1998, Virus research.

Proteins and messenger RNAs of the transforming region of wild-type and mutant adenoviruses.

M. Mathews, H. Esche, J. B. Lewis, 1980, Journal of molecular biology.

Coronary reoperation with and without cardiopulmonary bypass

U. Kappert, S. Tugtekin, K. Matschke, 2006, Clinical Research in Cardiology.

Recombinant gene products of two natural variants of the human cytidine deaminase gene confer different deamination rates of cytarabine in vitro.

S. Seeber, H. Esche, H. Kirch, 1998, Experimental hematology.

Transformation-defective adenovirus 5 E1A mutants exhibit antioncogenic properties in human BLM melanoma cells

S. Seeber, H. Esche, B. Opalka, 2000, Cancer Gene Therapy.

G Protein Regulation of the Na/H Antiporter in Xenopus laevis Oocytes

T. Wieland, K. Jakobs, W. Siffert, 1995, The Journal of Biological Chemistry.

Early Proteins Coded by the Adenovirus Genome: Functional Aspects

H. Esche, 1986 .

Structure and expression of adenovirus type 12 E1B 58K protein in infected and transformed cells: studies using antibodies directed against a synthetic peptide.

K. Schughart, H. Esche, E. Bause, 1985, Virus research.

Gene expression of bacteriophage SPP1

H. Esche, 1975, Molecular and General Genetics MGG.

A multiprotein complex consisting of the cellular coactivator p300, AP-1/ATF, as well as NF-kappaB is responsible for the activation of the mouse major histocompatibility class I (H-2K(b)) enhancer A.

B. Pützer, H. Esche, U. Schmücker, 1999, Gene expression.

Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.

H. Esche, H. Hennemann, B. Wilker, 1999, Virology.

Sprouty is a cytoplasmic target of adenoviral E1A oncoproteins to regulate the receptor tyrosine kinase signalling pathway

H. Esche, A. Zaremba, Ursula Schmuecker, 2011, Virology Journal.

Expression of early viral gene products in adenovirus type 12-infected and -transformed cells.

H. Esche, B. Siegmann, 1982, The Journal of general virology.

Gene expression of bacteriophage SPPI. I. Phage directed protein synthesis.

T. Trautner, H. Esche, M. Schweiger, 1975, Molecular & general genetics : MGG.

Early and late proteins of adenovirus type 12: translation mapping with RNA isolated from infected and transformed cells.

K. Schughart, H. Esche, M. Reuther, 1984, Current topics in microbiology and immunology.

cAMP-independent Activation of the Adenovirus Type 12 E2 Promoter Correlates with the Recruitment of CREB-1/ATF-1, E1A12S, and CBP to the E2-CRE*

H. Esche, K. Lipinski, D. Brockmann, 2000, The Journal of Biological Chemistry.

Regulation of viral and cellular gene expression by E1A proteins encoded by the oncogenic adenovirus type 12.

H. Esche, D. Brockmann, 1995, Current topics in microbiology and immunology.

Identification of the Full-Length Huntingtin- Interacting Protein p231HBP/HYPB as a DNA-Binding Factor

B. Pützer, T. Stiewe, S. Rega, 2001, Molecular and Cellular Neuroscience.

Number and function of CD 4 + CD 25 + FoxP 3 + regulatory T cells in patients suffering from multiple sclerosis

H. Esche, E. Kreuzfelder, 2007 .

Repression of the c-Jun trans-Activation Function by the Adenovirus Type 12 E1A 52R Protein Correlates with the Inhibition of Phosphorylation of the c-Jun Activation Domain (*)

H. Esche, C. Bury, H. Kirch, 1995, The Journal of Biological Chemistry.

Deletion of the β-turn/α-helix motif at the exon 2/3 boundary of human c-Myc leads to the loss of its immortalizing function

H. Esche, G. Zoidl, D. Brockmann, 1993 .

Cloning of adenovirus type 12 E1 genes into a retroviral vector and their differential splicing in mouse cells.

H. Esche, A. Schmidtmann, S. Fürst, 1990, Gene.

Expression of Adenovirus Type 12 13S Gene Product is Sufficient to Immortalize Primary Mouse Cells

H. Esche, D. Brockmann, B. Tries, 1991 .

E1A12S-mediated Activation of the Adenovirus Type 12 E2 Promoter Depends on the Histone Acetyltransferase Activity of p300/CBP*

H. Esche, D. Brockmann, O. Lehmkühler, 2000, The Journal of Biological Chemistry.

Expression of adenovirus type 12 E1b 58-kDa protein in Escherichia coli and production of antibodies raised against a 58-kDa::beta-galactosidase fusion protein.

K. Schughart, H. Esche, B. von Wilcken-Bergmann, 1987, Gene.

Expression of human p53 requires synergistic activation of transcription from the p53 promoter by AP-1, NF-κB and Myc/Max

H. Esche, H. Kirch, D. Brockmann, 1999, Oncogene.

The translational map of the Autographa californica nuclear polyhedrosis virus (AcNPV) genome.

W. Doerfler, H. Esche, H. Lübbert, 1982, The EMBO journal.

Transactivation-deficient ΔTA-p73 Acts as an Oncogene

B. Pützer, T. Stiewe, H. Esche, 2002 .

E1A 12S and 13S of the transformation-defective adenovirus type 12 strain CS-1 inactivate proteins of the RB family, permitting transactivation of the E2F-dependent promoter

B. Pützer, S. Rega, H. Esche, 1997, Journal of virology.

E 1 A 12 S and 13 S of the Transformation-Defective Adenovirus Type 12 Strain CS-1 Inactivate Proteins of the RB Family , Permitting Transactivation of the E 2 F-Dependent Promoter

B. Pützer, S. Rega, H. Esche, 1997 .

Induction of mutations in B. subtilis phage SPP1 by growth on host cells carrying a mutator DNA polymerase III

T. Trautner, H. Esche, M. Montenegro, 1976, Molecular and General Genetics MGG.

Asymmetric transcription of SPP1 in vivo

H. Esche, H. Spatz, 1973, Molecular and General Genetics MGG.

Formation of the early-region-2 transcription-factor-1-retinoblastoma-protein (E2F-1-RB) transrepressor and release of the retinoblastoma protein from nuclear complexes containing cyclin A is induced by interferon alpha in U937V cells but not in interferon-alpha-resistant U937VR cells.

H. Esche, H. Kirch, D. Brockmann, 1997, European journal of biochemistry.

Transactivation-deficient DeltaTA-p73 acts as an oncogene.

B. Pützer, T. Stiewe, H. Esche, 2002, Cancer research.

Selectively enhanced cellular signaling by Gi proteins in essential hypertension. G alpha i2, G alpha i3, G beta 1, and G beta 2 are not mutated.

D. Rosskopf, K. Jakobs, M. Montemurro, 1996, Circulation research.

Improved treatment of pancreatic cancer by IL-12 and B7.1 costimulation: antitumor efficacy and immunoregulation in a nonimmunogenic tumor model.

B. Pützer, M. Hitt, T. Stiewe, 2002, Molecular therapy : the journal of the American Society of Gene Therapy.

Viral gene products in adenovirus type-2 transformed hamster cells

H. Esche, 1982, Journal of virology.

In vitro translation of adenovirus type 12-specific mRNA isolated from infected and transformed cells

W. Doerfler, H. Esche, R. Schilling, 1979, Journal of virology.

Organization and expression of the left third of the genome of adenovirus.

B. Stillman, M. Mathews, M. Harter, 1980, Cold Spring Harbor symposia on quantitative biology.

A cis-acting element 7 bp upstream of the ESF-1-binding motif is involved in E1A 13S autoregulation of the adenovirus 12 TS2 promoter.

B. Pützer, H. Esche, H. Kirch, 1997, The Journal of general virology.

Isolation and characterization of novel adenovirus type 12 E1A mRNAs by cDNA PCR technique.

H. Esche, D. Brockmann, B. Tries, 1990, Virology.

Two domains within the adenovirus type 12 E1A unique spacer have disparate effects on the interaction of E1A with P105-Rb and the transformation of primary mouse cells.

H. Esche, H. Kirch, H. Rumpf, 1999, Virology.

Tumor-specific activation of hTERT-derived promoters by tumor suppressive E1A-mutants involves recruitment of p300/CBP/HAT and suppression of HDAC-1 and defines a combined tumor targeting and suppression system

J. Barrett, I. Horikawa, U. Hengge, 2002, Oncogene.

Gene expression of bacteriophage SPP1

T. Trautner, H. Esche, M. Schweiger, 1975, Molecular and General Genetics MGG.

Modified syringe design prevents plunger-related contamination--results of contamination and flow-rate tests.

U Wolfhard, D Kendoff, L C Olivier, 2003, The Journal of hospital infection.

The adenovirus type 12 ‐ mouse cell system: permissivity and analysis of integration patterns of viral DNA in tumor cells.

W. Doerfler, A. Starzinski-Powitz, H. Esche, 1982, The EMBO journal.