N. Lassam

发表

Mutation of the CDKN2A 5' UTR creates an aberrant initiation codon and predisposes to melanoma

David Hogg, D. Dilworth, D. Hogg, 1999, Nature Genetics.

CDKN2A mutations in multiple primary melanomas.

M. Tucker, A. Goldstein, D. Hogg, 1998, The New England journal of medicine.

HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway.

T. Pawson, J. Woodgett, B. Zanke, 1996, The EMBO journal.

Mixed-Lineage Kinase 3 Delivers CD3/CD28-Derived Signals into the IκB Kinase Complex

T. Hofmann, C. Scheidereit, W. Dröge, 2000, Molecular and Cellular Biology.

Lack of germline CDK6 mutations in familial melanoma

M. Tucker, A. Goldstein, D. Hogg, 2000, Oncogene.

Melanoma in adolescents: A case‐control study of risk factors in Queensland, Australia

N. Martin, J. Aitken, N. Hayward, 2002, International journal of cancer.

Germline splicing mutations of CDKN2A predispose to melanoma

M. Tucker, A. Goldstein, H. Lynch, 2003, Oncogene.

Genetic Testing in Familial Melanoma : Epidemiologic/Genetic Assessment of Risks and Role of CDKN2A Analysis.

D. Hogg, N. Lassam, L. Liu, 2001, Methods in molecular medicine.

Patients with both pancreatic adenocarcinoma and melanoma may harbor germline CDKN2A mutations

S. Gallinger, M. Redston, D. Hogg, 2000, Genes, chromosomes & cancer.

Germline p16INK4A mutation and protein dysfunction in a family with inherited melanoma.

J. Slingerland, D. Hogg, Ling Liu, 1995, Oncogene.

Expression of the MAGE-1 tumor antigen is up-regulated by the demethylating agent 5-aza-2'-deoxycytidine.

M. Herlyn, D. Samid, S. Rosenberg, 1994, Cancer research.

Tissue distribution of SNAP-23 and its subcellular localization in 3T3-L1 cells.

A. Klip, N. Lassam, A. Volchuk, 1997, Biochemical and biophysical research communications.

Reversible thrombocytopenia with levamisole.

N. Lassam, E. Winquist, 1995, Medical and pediatric oncology.

A phase I study of adenovirus mediated gene transfer of interleukin 2 cDNA into metastatic breast cancer or melanoma.

F. Graham, A. Stewart, N. Lassam, 1997, Human gene therapy.

Suppression of MHC class I RNA in highly oncogenic cells occurs at the level of transcription initiation.

G. Jay, N. Lassam, 1989, Journal of immunology.

Concurrent acute lymphoblastic leukemia and juvenile pilocytic astrocytoma in a pediatric patient.

D. Hogg, N. Lassam, W. Greer, 2000, Journal of pediatric hematology/oncology.

CDKN2A mutation in a non‐FAMMM kindred with cancers at multiple sites results in a functionally abnormal protein

P. Pollock, W. Foulkes, N. Hayward, 1997, International journal of cancer.

Overexpression of p 53 Is a Late Event in the Development of Malignant Melanoma 1

N. Lassam, L. From, H. Kahn, 2006 .

Overexpression of p53 is a late event in the development of malignant melanoma.

N. Lassam, L. From, H. Kahn, 1993, Cancer research.

The Kinase Activation Loop Is the Key to Mixed Lineage Kinase-3 Activation via Both Autophosphorylation and Hematopoetic Progenitor Kinase 1 Phosphorylation*

N. Lassam, Irene W. L. Leung, Irene Leung, 2001, The Journal of Biological Chemistry.

Germline CDKN2A mutation implicated in predisposition to multiple myeloma.

D. Dilworth, A. Stewart, D. Hogg, 2000, Blood.

Affected members of melanoma‐prone families with linkage to 9p21 but lacking mutations in CDKN2A do not harbor mutations in the coding regions of either CDKN2B or p19ARF

M. Tucker, A. Goldstein, D. Hogg, 1997 .

Affected members of melanoma-prone families with linkage to 9p21 but lacking mutations in CDKN2A do not harbor mutations in the coding regions of either CDKN2B or p19ARF.

M. Tucker, A. Goldstein, D. Hogg, 1997, Genes, chromosomes & cancer.

Fine mapping of the MLK-3 gene within 11q13 and its exclusion as the MEN1 susceptibility gene

C. Larsson, B. Teh, N. Lassam, 1997, Human Genetics.

MLK-3: identification of a widely-expressed protein kinase bearing an SH3 domain and a leucine zipper-basic region domain.

H. Heng, L. Tsui, N. Lassam, 1994, Oncogene.

Malignant melanoma in patients with multiple endocrine neoplasia type 1 and involvement of the MEN1 gene in sporadic melanoma

C. Larsson, B. Teh, G. Robertson, 2000, International journal of cancer.

Loss of c-kit expression in cultured melanoma cells.

N. Lassam, S. Bickford, 1992, Oncogene.

Lack of GermLine Mutations of CDK 4 , p 16 ’ 4 ” , and 15 INK 4 B in Families with Glioma ’

Gao, Ling, David, 2005 .

Lack of germ-line mutations of CDK4, p16(INK4A), and p15(INK4B) in families with glioma.

D. Hogg, N. Lassam, R. Jenkins, 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

Absence of the L37P polymorphism in exon 1 of the CDKN2A gene.

J. Fung, D. Hogg, J. Monzon, 1997, Molecular and cellular probes.

Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase 1 clinical trial

S. Gallinger, F. Graham, N. Lassam, 1999, Gene Therapy.

Tumor antigens of human ad5 in transformed cells and in cells infected with transformation-defective host-range mutants

F. Graham, S. Bayley, N. Lassam, 1979, Cell.

Protein kinase activity immunoprecipitated from adenovirus infected cells by sera from tumor-bearing hamsters

P. Branton, F. Graham, S. Bayley, 1981, Journal of virology.

Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma–pancreatic carcinoma–prone families

S. Kern, J. Knezetic, R. Brand, 2002, Cancer.

Two p16 (CDKN2A) germline mutations in 30 Israeli melanoma families

G. Peters, E. Friedman, S. Brookes, 2000, European Journal of Human Genetics.

Dimerization via Tandem Leucine Zippers Is Essential for the Activation of the Mitogen-activated Protein Kinase Kinase Kinase, MLK-3*

N. Lassam, I. Leung, 1998, The Journal of Biological Chemistry.

MLK‐3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6.

J. Woodgett, N. Lassam, N. Iscove, 1996, The EMBO journal.

The mouse homologs of RELA and MLK3 are located within a 120-kb fragment on Chromosome 19

C. Larsson, J. Guénet, N. Lassam, 1997, Mammalian Genome.

Synthesis of DNA, late polypeptides, and infectious virus by host-range mutants of adenovirus 5 in nonpermissive cells.

F. Graham, S. Bayley, N. Lassam, 1978, Virology.

VEGF receptor subtypes KDR and FLT1 show different sensitivities to heparin and placenta growth factor.

D. Gospodarowicz, N. Lassam, M. Persico, 1994, Growth factors.

Protein kinases in normal and transformed melanocytes

M. Herlyn, N. Lassam, Y. Ing, 1994, Melanoma research.

Expression of p53 in dysplastic nevi and malignant melanoma: 339

N. Lassam, L. From, H. Kahn, 1993 .

A reexamination of the leucine tRNAs and the leucyl-tRNA synthetase in developing Tenebrio molitor.

B. White, N. Lassam, H. Lerer, 1976, Developmental biology.

An Analysis of Leucine tRNAs during the Development of Tenebrio molitor

B. White, N. Lassam, H. Lerer, 1976 .

Transforming proteins of human adenovirus 5: studies with infected and transformed cells.

F. Graham, S. Bayley, N. Lassam, 1980, Cold Spring Harbor symposia on quantitative biology.

Translational control in the mealworm, Tenebrio molitor

B. White, N. Lassam, NORMAN J. LASSAM, 1975, Nature.

Role of the Cyclin-Dependent Kinase Inhibitor CDKN2A in Familial Melanoma

D. Hogg, A. Summers, N. Lassam, 1998, Journal of cutaneous medicine and surgery.

Immunoprecipitation of protein kinase activity from adenovirus 5-infected cells using antiserum directed against tumour antigens

P. Branton, F. Graham, S. Bayley, 1979, Nature.