D. A. Foster

D. A. Foster, C. M. Drain, L. Hui, 2008, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

Association between v-Src and protein kinase C delta in v-Src-transformed fibroblasts.

D. Shalloway, D. A. Foster, Z. Lu, 1997, The Journal of biological chemistry.

Suppression of cell migration by protein kinase Cδ

K. Nakayama, K. Nakayama, D. A. Foster, 2005, Oncogene.

Novel Tumor-promoting Property of Tamoxifen 1

T. Abbas, Zhimin Lu, A. Hornia, 2001 .

Novel tumor-promoting property of tamoxifen.

T. Abbas, A. Hornia, D. A. Foster, 2001, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Inhibition of S6 kinase suppresses the apoptotic effect of eIF4E ablation by inducing TGF-β-dependent G1 cell cycle arrest.

D. A. Foster, Paige Yellen, A. Chatterjee, 2013, Cancer letters.

Suppression TGF-β Signaling by Phospholipase D

D. A. Foster, N. Gadir, A. Toschi, 2007 .

Phosphatidic acid signaling to mTOR: signals for the survival of human cancer cells.

D. A. Foster, 2009, Biochimica et biophysica acta.

Involvement of Ral GTPase in v-Src-induced phospholipase D activation

Zhimin Lu, T. Urano, P. Frankel, 1995, Nature.

Phospholipase D provides a survival signal in human cancer cells with activated H-Ras or K-Ras.

M. Shi, D. A. Foster, Lizhong Xu, 2007, Cancer letters.

Elevated Phospholipase D Activity in H-Ras- but Not K-Ras-Transformed Cells by the Synergistic Action of RalA and ARF6

C. D’Souza-Schorey, P. Frankel, D. A. Foster, 2003, Molecular and Cellular Biology.

Phospholipase D Couples Survival and Migration Signals in Stress Response of Human Cancer Cells*

M. Shi, D. A. Foster, L. Hui, 2006, Journal of Biological Chemistry.

Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation.

P. Greengard, W. Netzer, Huaxi Xu, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Differential Raf requirement for activation of mitogen-activated protein kinase by growth factors, phorbol esters, and calcium.

U. Rapp, M. Rosner, D. A. Foster, 1994, The Journal of biological chemistry.

(-)-Oleocanthal and (-)-oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells

D. A. Foster, P. Breslin, George Zhang, 2019, bioRxiv.

Targeting mTOR with rapamycin: One dose does not fit all

D. A. Foster, A. Toschi, 2009, Cell cycle.

Phospholipase D–dependent mTOR complex 1 (mTORC1) activation by glutamine

D. A. Foster, D. Menon, M. Frias, 2018, The Journal of Biological Chemistry.

Suppression of TGF-beta signaling by phospholipase D.

D. A. Foster, N. Gadir, A. Toschi, 2007, Cell cycle.

Apoptotic effects of high-dose rapamycin occur in S-phase of the cell cycle

D. A. Foster, Mahesh Saqcena, S. Mukhopadhyay, 2015, Cell cycle.

Region of Viral Oncogenes That Encodes the Tyrosine

G. Daley, D. A. Foster, M. Simon, 2003 .

Phospholipase D stabilizes HDM2 through an mTORC2/SGK1 pathway.

D. A. Foster, Limei Xu, D. Lyo, 2010, Biochemical and biophysical research communications.

Activation of the transformation potential of the cellular fps gene

M. Shibuya, H. Hanafusa, D. A. Foster, 1985, Cell.

Cancer cells with defective RB and CDKN2A are resistant to the apoptotic effects of rapamycin.

D. A. Foster, M. Frias, Matthew Utter, 2021, Cancer letters.

Antagonistic effects of protein kinase C alpha and delta on both transformation and phospholipase D activity mediated by the epidermal growth factor receptor.

A. Hornia, T. Sukezane, T. Joseph, 1999, Molecular and cellular biology.

Evidence that v-Src-induced phospholipase D activity is mediated by a G protein

D. A. Foster, K. Alexandropoulos, H. Jiang, 1994, Molecular and cellular biology.

The induction of Egr-1 expression by v-Fps is via a protein kinase C-independent intracellular signal that is sequentially dependent upon HaRas and Raf-1.

U. Rapp, J. Bruder, D. A. Foster, 1992, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Phospholipase D Mediates Nutrient Input to Mammalian Target of Rapamycin Complex 1 (mTORC1)*

D. A. Foster, Paige Yellen, Limei Xu, 2011, The Journal of Biological Chemistry.

Lipid sensing by mTOR complexes via de novo synthesis of phosphatidic acid

R. Deberardinis, Pei-Hsuan Chen, D. A. Foster, 2017, The Journal of Biological Chemistry.

Mitogenic phospholipase D activity is restricted to caveolin-enriched membrane microdomains.

T. Joseph, P. Frankel, D. A. Foster, 2000, Biochemical and biophysical research communications.

A low molecular weight factor from dividing cells activates phospholipase D in caveolin-enriched membrane microdomains.

D. A. Foster, S. Bychenok, 2000, Archives of biochemistry and biophysics.

ETS transcription factors regulate an enhancer activity in the third intron of TNF‐α

D. A. Foster, G. Tomaras, S. Taffet, 1999, Journal of leukocyte biology.

Inhibiting glutamine utilization creates a synthetic lethality for suppression of ATP citrate lyase in KRas-driven cancer cells

D. A. Foster, D. Menon, M. Frias, 2022, PloS one.

Ral and Rho-dependent activation of phospholipase D in v-Raf-transformed cells.

U. Rapp, T. Joseph, P. Frankel, 1999, Biochemical and biophysical research communications.

Phospholipase D and the Maintenance of Phosphatidic Acid Levels for Regulation of Mammalian Target of Rapamycin (mTOR)*

D. A. Foster, D. Menon, M. Frias, 2014, The Journal of Biological Chemistry.

Activation of gene expression by a non-transforming unmyristylated-SH3-deleted mutant of Src is dependent upon Tyr-527.

P. Frankel, D. A. Foster, M. Curto, 1997, Biochemical and biophysical research communications.

v-Src activates mitogen-responsive transcription factor Egr-1 via serum response elements.

V. Sukhatme, D. A. Foster, X. Cao, 1991, The Journal of biological chemistry.

5-Aminoimidazole-4-carboxamide-1-β-4-ribofuranoside (AICAR) enhances the efficacy of rapamycin in human cancer cells

D. A. Foster, S. Mukhopadhyay, Deven D Patel, 2015, Cell cycle.

Functional association between Arf and RalA in active phospholipase D complex.

R. Kahn, P. Frankel, D. A. Foster, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Evidence that Ha-Ras mediates two distinguishable intracellular signals activated by v-Src.

U. Rapp, J. Bruder, D. A. Foster, 1992, The Journal of biological chemistry.

v-Src increases diacylglycerol levels via a type D phospholipase-mediated hydrolysis of phosphatidylcholine

L. Pfeffer, D. A. Foster, J. Song, 1991, Molecular and cellular biology.

The enigmatic protein kinase C (cid:1) : complex roles in cell proliferation and survival

D. A. Foster, D. Jackson, 2020 .

Cloning and characterization of a thermolabile v-src gene for use in reversible transformation of mammalian cells.

J. Brugge, A. Maroney, D. A. Foster, 1992, Oncogene.

A fps gene without gag gene sequences transforms cells in culture and induces tumors in chickens

H. Hanafusa, D. A. Foster, 1983, Journal of virology.

An inhibitory mutant of c-Raf-1 blocks v-Src-induced activation of the Egr-1 promoter.

W. Kolch, V. Sukhatme, U. Rapp, 1991, The Journal of biological chemistry.

RalA mediates v-Src, v-Ras, and v-Raf regulation of CD44 and fibronectin expression in NIH3T3 fibroblasts.

J. Aguirre-Ghiso, E. D. Bal de Kier Joffé, P. Frankel, 2001, Biochemical and biophysical research communications.

Phospholipase D2 stimulates cell protrusion in v-Src-transformed cells.

D. A. Foster, Yingjie Shen, Yang-Yu Zheng, 2002, Biochemical and biophysical research communications.

RalA requirement for v-Src- and v-Ras-induced tumorigenicity and overproduction of urokinase-type plasminogen activator: involvement of metalloproteases

Zhimin Lu, J. Aguirre-Ghiso, P. Frankel, 1999, Oncogene.

Efficient synthesis and photodynamic activity of porphyrin-saccharide conjugates: targeting and incapacitating cancer cells.

D. A. Foster, C. M. Drain, L. Hui, 2004, Biochemistry.

Activation of Protein Kinase C Triggers Its Ubiquitination and Degradation

M. Pagano, Zhimin Lu, A. Hornia, 1998, Molecular and Cellular Biology.

An EGF receptor/Ral‐GTPase signaling cascade regulates c‐Src activity and substrate specificity

M. Shipitsin, Zhimin Lu, D. A. Foster, 2000, The EMBO journal.

The enigmatic protein kinase Cδ: complex roles in cell proliferation and survival

D. A. Foster, D. Jackson, Desmond N. Jackson, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Association between v-Src and Protein Kinase C δ in v-Src-transformed Fibroblasts*

D. Shalloway, Zhimin Lu, D. A. Foster, 1997, The Journal of Biological Chemistry.

Selective activation of protein kinase C isoforms by v-Src.

P. Frankel, D. A. Foster, Q. Zang, 1995, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

The Enigma of Rapamycin Dosage

D. A. Foster, Paige Yellen, S. Mukhopadhyay, 2016, Molecular Cancer Therapeutics.

Aspartate Rescues S-phase Arrest Caused by Suppression of Glutamine Utilization in KRas-driven Cancer Cells*

D. A. Foster, D. Loayza, D. Menon, 2016, The Journal of Biological Chemistry.

Blocking anaplerotic entry of glutamine to TCA cycle sensitizes K-Ras mutant cancer cells to cytotoxic drugs

D. A. Foster, Mahesh Saqcena, S. Mukhopadhyay, 2014, Oncogene.

Reciprocal Regulation of AMP-activated Protein Kinase and Phospholipase D*

D. A. Foster, Mahesh Saqcena, S. Mukhopadhyay, 2015, The Journal of Biological Chemistry.

Mutant p53 in MDA-MB-231 breast cancer cells is stabilized by elevated phospholipase D activity and contributes to survival signals generated by phospholipase D

J. Bargonetti, D. A. Foster, L. Hui, 2006, Oncogene.

Differential Dependence of Hypoxia-inducible Factors 1α and 2α on mTORC1 and mTORC2*

M. Ohh, D. A. Foster, N. Gadir, 2008, Journal of Biological Chemistry.

Cell Growth Checkpoint ( s ) Regulation of G 1 Cell Cycle Progression : Distinguishing the Restriction Point from a Nutrient-Sensing

D. A. Foster, Paige Yellen, Limei Xu, 2011 .

Suppression of hypoxia-inducible factor 2alpha restores p53 activity via Hdm2 and reverses chemoresistance of renal carcinoma cells.

M. Ohh, D. A. Foster, I. Watson, 2009, Cancer research.

Suppression of AKT Phosphorylation Restores Rapamycin-Based Synthetic Lethality in SMAD4-Defective Pancreatic Cancer Cells

D. A. Foster, M. Frias, Matthew Utter, 2013, Molecular Cancer Research.

Regulation of mTORC1 and mTORC2 Complex Assembly by Phosphatidic Acid: Competition with Rapamycin

D. A. Foster, Limei Xu, N. Gadir, 2008, Molecular and Cellular Biology.

High-dose rapamycin induces apoptosis in human cancer cells by dissociating mTOR complex 1 and suppressing phosphorylation of 4E-BP1

V. Rodrik-Outmezguine, D. A. Foster, Paige Yellen, 2011, Cell cycle.

Targeting Phospholipase D-mediated Survival Signals in Cancer

D. A. Foster, 2006 .

Targeting mTOR-mediated survival signals in anticancer therapeutic strategies

D. A. Foster, 2004, Expert review of anticancer therapy.

mTOR-dependent Suppression of Protein Phosphatase 2A Is Critical for Phospholipase D Survival Signals in Human Breast Cancer Cells*

D. A. Foster, R. Pielak, L. Hui, 2005, Journal of Biological Chemistry.

Resistance of Adenoviral DNA Replication to Aphidicolin Is Dependent on the 72-Kilodalton DNA-Binding Protein

D. A. Foster, P. Hantzopoulos, G. Zubay, 1982, Journal of virology.

Intracellular signalling mediated by protein-tyrosine kinases: networking through phospholipid metabolism.

D. A. Foster, 1993, Cellular signalling.

Honokiol Suppresses Survival Signals Mediated by Ras-Dependent Phospholipase D Activity in Human Cancer Cells

D. Bar-Sagi, J. Arbiser, H. Brown, 2008, Clinical Cancer Research.

Amino Acids and mTOR Mediate Distinct Metabolic Checkpoints in Mammalian G 1 Cell Cycle

D. A. Foster, Mahesh Saqcena, S. Mukhopadhyay, 2016 .

The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2

Michael Loran Dustin, D. A. Foster, G. Du, 2007, Nature Cell Biology.

MARCKS protein is transcriptionally down-regulated in v-Src-transformed BALB/c 3T3 cells.

D. A. Foster, D. Wallace, C. Joseph, 1992, The Journal of biological chemistry.

Phospholipase D and RalA Cooperate with the Epidermal Growth Factor Receptor To Transform 3Y1 Rat Fibroblasts

Zhimin Lu, A. Hornia, T. Sukezane, 2000, Molecular and Cellular Biology.

Inhibition of Human p53 Basal Transcription by Down-regulation of Protein Kinase Cδ*

J. Bargonetti, T. Abbas, D. A. Foster, 2004, Journal of Biological Chemistry.

Survival Signals Generated by Estrogen and Phospholipase D in MCF-7 Breast Cancer Cells Are Dependent on Myc

D. A. Foster, Yuhong Chen, Yang-Yu Zheng, 2005, Molecular and Cellular Biology.

RalA interacts directly with the Arf-responsive, PIP2-dependent phospholipase D1.

S. Hammond, D. A. Foster, M. Frohman, 1997, Biochemical and biophysical research communications.

Phosphatidic acid and lipid-sensing by mTOR

D. A. Foster, 2013, Trends in Endocrinology & Metabolism.

HIFα expression in VHL-deficient renal cancer cells is dependent on phospholipase D

M. Ohh, D. A. Foster, J. Edelstein, 2008, Oncogene.

Elevated phospholipase D activity in androgen-insensitive prostate cancer cells promotes both survival and metastatic phenotypes.

Yuan-Shan Zhu, D. A. Foster, Matthew Utter, 2018, Cancer letters.

Isolation of chicken cellular DNA sequences with homology to the region of viral oncogenes that encodes the tyrosine kinase domain

G. Daley, H. Hanafusa, D. A. Foster, 1986, Molecular and cellular biology.

Phosphatidylcholine-specific phospholipase D activity is elevated in v-Fps-transformed cells.

D. A. Foster, J. Song, Y. Jiang, 1994, Biochemical and biophysical research communications.

Epidermal growth factor induces the production of biologically distinguishable diglyceride species from phosphatidylinositol and phosphatidylcholine via the independent activation of type C and type D phospholipases.

D. A. Foster, J. Song, Y. Jiang, 1994, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Glutamine as an Essential Amino Acid for KRas-Driven Cancer Cells

D. A. Foster, Elyssa Bernfeld, 2019, Trends in Endocrinology & Metabolism.

v-Src activates both protein kinase C-dependent and independent signaling pathways in murine fibroblasts.

A. Maroney, D. A. Foster, C. Joseph, 1991, Oncogene.

A dominant negative Raf-1 mutant prevents v-Src-induced transformation.

U. Rapp, J. Bruder, D. A. Foster, 1993, Biochemical and biophysical research communications.

Ras Mediates the Activation of Phospholipase D by v-Src (*)

A. Wolfman, Zhimin Lu, D. A. Foster, 1995, The Journal of Biological Chemistry.

Downregulating PKC δ provides a PI3K/Akt-independent survival signal that overcomes apoptotic signals generated by c-Src overexpression

Zhimin Lu, D. A. Foster, Minghao Zhong, 2002, Oncogene.

Defective TGF-beta signaling sensitizes human cancer cells to rapamycin.

D. A. Foster, D. Jackson, N. Gadir, 2008, Oncogene.

Myc stabilization in response to estrogen and phospholipase D in MCF‐7 breast cancer cells

D. A. Foster, L. Hui, Evan Gomes, 2006, FEBS letters.

Phospholipase D Elevates the Level of MDM2 and Suppresses DNA Damage-Induced Increases in p53

J. Bargonetti, T. Abbas, T. Joseph, 2004, Molecular and Cellular Biology.

Phospholipase D overcomes cell cycle arrest induced by high-intensity Raf signaling

U. Rapp, T. Joseph, P. Frankel, 2002, Oncogene.

[Can defective TGF-Beta signaling be an Achilles heel in human cancer?].

D. A. Foster, N. Gadir, 2008, Ai zheng = Aizheng = Chinese journal of cancer.

Alternative phospholipase D/mTOR survival signal in human breast cancer cells

David A Foster, D. A. Foster, Yuhong Chen, 2005, Oncogene.

Elevated phospholipase D activity induces apoptosis in normal rat fibroblasts.

T. Joseph, D. A. Foster, D. Jackson, 2002, Biochemical and biophysical research communications.

Phospholipase D-mTOR requirement for the Warburg effect in human cancer cells.

M. Ohh, D. A. Foster, C. M. Drain, 2010, Cancer letters.

Phospholipase D confers rapamycin resistance in human breast cancer cells

D. A. Foster, Yuhong Chen, Yang-Yu Zheng, 2003, Oncogene.

Garcinia benzophenones inhibit the growth of human colon cancer cells and synergize with sulindac sulfide and turmeric.

E. Kennelly, D. A. Foster, M. Figueroa, 2013, Anti-cancer agents in medicinal chemistry.

Oleocanthal and oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells

D. A. Foster, P. Breslin, George Zhang, 2019, bioRxiv.

1-beta-D-arabinofuranosylcytosine stimulates thymidine incorporation into the DNA of contact-inhibited cells.

D. A. Foster, 1981, Experimental cell research.

Inhibition of fatty acid synthase induces pro-survival Akt and ERK signaling in K-Ras-driven cancer cells.

D. A. Foster, Paige Yellen, 2014, Cancer letters.

Mammalian Target of Rapamycin ( mTOR ) Phosphatidic Acid Levels for Regulation of Phospholipase D and the Maintenance of Minireviews

D. A. Foster, D. Menon, M. Frias, 2014 .

v-Src activates a unique phospholipase D activity that can be distinguished from the phospholipase D activity activated by phorbol esters.

D. A. Foster, J. Song, 1993, The Biochemical journal.

Phospholipase D prevents apoptosis in v-Src-transformed rat fibroblasts and MDA-MB-231 breast cancer cells.

T. Joseph, D. A. Foster, D. Jackson, 2003, Biochemical and biophysical research communications.

Transformation of cells overexpressing a tyrosine kinase by phospholipase D1 and D2.

T. Joseph, D. A. Foster, Z. Lu, 2001, Biochemical and biophysical research communications.

HIF alpha expression in VHL-deficient renal cancer cells is dependent on phospholipase D.

M. Ohh, D. A. Foster, J. Edelstein, 2008, Oncogene.

Reduced mortality and moderate alcohol consumption: The phospholipase D-mTOR connection

D. A. Foster, 2010, Cell cycle.

Cholera toxin induces expression of the immediate-early response gene JE via a cyclic AMP-independent signaling pathway

D. A. Foster, K. Alexandropoulos, Sajjad A. Qureshi, 1991, Molecular and cellular biology.

Amino Acids and mTOR Mediate Distinct Metabolic Checkpoints in Mammalian G1 Cell Cycle

D. A. Foster, Mahesh Saqcena, S. Mukhopadhyay, 2013, PloS one.

Regulation of mTOR by phosphatidic acid

D. A. Foster, M. Frias, A. Hatipoğlu, 2023, Trends in Endocrinology & Metabolism.

A Late G1 Lipid Checkpoint That Is Dysregulated in Clear Cell Renal Carcinoma Cells*

M. Ohh, D. A. Foster, Mahesh Saqcena, 2016, The Journal of Biological Chemistry.

Sustained induction of egr-1 by v-src correlates with a lack of fos-mediated repression of the egr-1 promoter.

V. Sukhatme, D. A. Foster, K. Alexandropoulos, 1992, Oncogene.

Signal transduction through lipid second messengers.

S. Spiegel, R. Kolesnick, D. A. Foster, 1996, Current opinion in cell biology.

BxPC3 pancreatic cancer cells express a truncated Smad4 protein upon PI3K and mTOR inhibition

D. A. Foster, O. Legendre, Ayisha Sookdeo, 2014, Oncology letters.

Evidence that activation of the Egr-1 promoter by v-Raf involves serum response elements.

V. Sukhatme, D. Gius, D. A. Foster, 1992, Oncogene.

Isolation ofChicken Cellular DNA Sequences withHomology tothe Region ofViral Oncogenes ThatEncodes theTyrosine

G. Daley, D. A. Foster, J. Levy, 1986 .

Evidence that a G-protein transduces signals initiated by the protein-tyrosine kinase v-Fps.

D. A. Foster, K. Alexandropoulos, C. Joseph, 1991, The Journal of biological chemistry.

Regulation of G1 Cell Cycle Progression: Distinguishing the Restriction Point from a Nutrient-Sensing Cell Growth Checkpoint(s).

D. A. Foster, Paige Yellen, Limei Xu, 2010, Genes & cancer.

Mutant Ras Elevates Dependence on Serum Lipids and Creates a Synthetic Lethality for Rapamycin

D. A. Foster, S. Mukhopadhyay, Darin Salloum, 2014, Molecular Cancer Therapeutics.

Regulation of mTOR by phosphatidic acid?

D. A. Foster, 2007, Cancer research.

Evidence that v-src and v-fps gene products use a protein kinase C-mediated pathway to induce expression of a transformation-related gene.

D. A. Foster, K. Berg, C. Joseph, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Metabolic vulnerability of KRAS-driven cancer cells

D. A. Foster, 2014, Molecular & cellular oncology.

Regulation of mTORC1 and mTORC2 Complex Assembly by Phosphatidic Acid: Competition with Rapamycin

D. A. Foster, Limei Xu, N. Gadir, 2008, Molecular and Cellular Biology.

Ha-Ras functions downstream from protein kinase C in v-Fps-induced gene expression mediated by TPA response elements.

D. A. Foster, K. Alexandropoulos, S. Qureshi, 1993, Oncogene.

Albumin promotes the progression of fibroblasts through late G1 into S-phase in the absence of growth factors

D. A. Foster, Sharmeen Uddin, Nataliya Melnyk, 2020, Cell cycle.