M. G. O’Sullivan

发表

Strain-dependent lung tumor formation in mice transplacentally exposed to 3-methylcholanthrene and post-natally exposed to butylated hydroxytoluene.

A. Malkinson, M. Miller, K. M. Gressani, 1999, Carcinogenesis.

Molecular pathogenesis of transplacentally induced mouse lung tumors.

M. Miller, S. Leone‐Kabler, M. G. O’Sullivan, 1998, Experimental lung research.

Role of tumor suppressor genes in transplacental lung carcinogenesis

S. Leone‐Kabler, M. G. O’Sullivan, L. Rollins, 1998, Molecular carcinogenesis.

A Transposon-Based Genetic Screen in Mice Identifies Genes Altered in Colorectal Cancer

Y. Asmann, S. Thibodeau, A. Oberg, 2009, Science.

PVT1 dependence in cancer with MYC copy-number increase

D. Largaespada, Y. Kawakami, B. Moriarity, 2014, Nature.

Inhaled carbon monoxide reduces leukocytosis in a murine model of sickle cell disease.

M. G. O’Sullivan, G. Vercellotti, R. Hebbel, 2009, American journal of physiology. Heart and circulatory physiology.

Helq acts in parallel to Fancc to suppress replication-associated genome instability

M. G. O’Sullivan, N. Shima, Spencer W. Luebben, 2013, Nucleic acids research.

Safety and Preclinical Efficacy of Aerosol Pioglitazone on Lung Adenoma Prevention in A/J Mice

V. Steele, F. Ondrey, M. G. O’Sullivan, 2016, Cancer Prevention Research.

Evaluation of protein kinase CK2 as a therapeutic target for squamous cell carcinoma of cats.

J. Modiano, M. G. O’Sullivan, G. Unger, 2017, American journal of veterinary research.

Lipopolysaccharide Enhances Mouse Lung Tumorigenesis

M. G. O’Sullivan, F. Kassie, X. Qian, 2013, Veterinary pathology.

A monocyte‐TNF‐endothelial activation axis in sickle transgenic mice: Therapeutic benefit from TNF blockade

N. Mackman, M. G. O’Sullivan, G. Vercellotti, 2017, American journal of hematology.

Transposon Mutagenesis Screen Identifies Potential Lung Cancer Drivers and CUL3 as a Tumor Suppressor

Sean R. Landman, Madison T. Weg, M. Steinbach, 2015, Molecular Cancer Research.

Precision Targeted Ablation of Fine Neurovascular Structures In Vivo Using Dual-mode Ultrasound Arrays

E. Ebbini, M. G. O’Sullivan, H. Clark, 2020, Scientific Reports.

Contribution of the innate and adaptive immune systems to aortic dilation in murine mucopolysaccharidosis type I.

J. Tolar, M. G. O’Sullivan, D. Seelig, 2022, Molecular genetics and metabolism.

Simian Parvovirus Infection in Cynomolgus Monkey Heart Transplant Recipients Causes Death Related to Severe Anemia

R. Pierson, M. G. O’Sullivan, S. Pfeiffer, 2006, Transplantation.

Nfatc2 and Tob1 Have Non-Overlapping Function in T Cell Negative Regulation and Tumorigenesis

J. Modiano, D. Bellgrau, M. G. O’Sullivan, 2014, PloS one.

CD4+ T cell anergy prevents autoimmunity and generates regulatory T cell precursors

Jonathan L. Linehan, K. Hogquist, M. Jenkins, 2015, Nature Immunology.

Establishment of a Patient-Derived Xenograft of Canine Enteropathy-Associated T-Cell Lymphoma, Large Cell Type.

J. Modiano, M. G. O’Sullivan, D. Seelig, 2017, Journal of comparative pathology.

Fatty acid synthase as a potential therapeutic target in feline oral squamous cell carcinoma

M. G. O’Sullivan, E. Dickerson, A. Khammanivong, 2018, Veterinary and comparative oncology.

Simian parvovirus infection: a potential zoonosis.

M. G. O’Sullivan, K. Brown, Susan Wong, 2004, The Journal of infectious diseases.

Inhaled Furan Selectively Damages Club Cells in Lungs of A/J Mice

M. G. O’Sullivan, L. Peterson, T. Wiedmann, 2019, Toxicologic pathology.

Abbreviations ALT : Alanine aminotransferase AST : Aspartate transaminase BUN : Blood urea nitrogen CPK : Creatine phosphokinase CR : Complete response DLT : Dose limiting toxicity FOSCC : Feline oral squamous cell carcinoma

J. Modiano, M. G. O’Sullivan, G. Unger, 2017 .

Splice Junction Map of Simian Parvovirus Transcripts

M. G. O’Sullivan, K. Brown, K. Faaberg, 2004, Journal of Virology.

Identification of a novel simian parvovirus in cynomolgus monkeys with severe anemia. A paradigm of human B19 parvovirus infection.

N. Young, J. Fikes, M. G. O’Sullivan, 1994, The Journal of clinical investigation.

Urinary calculus caused by plant material in a cynomolgus monkey.

M. G. O’Sullivan, C. Lees, C. Carlson, 1995, Laboratory animal science.

Histone Deacetylase Sirtuin 1 Promotes Loss of Primary Cilia in Cholangiocarcinoma

N. Giama, L. Roberts, Rendong Yang, 2021, Hepatology.

A novel gene editing system to treat both Tay–Sachs and Sandhoff diseases

D. Ory, M. G. O’Sullivan, C. Whitley, 2020, Gene Therapy.

Activity of a Novel Combined Antiretroviral Therapy of Gemcitabine and Decitabine in a Mouse Model for HIV-1

L. M. Mansky, M. G. O’Sullivan, C. Clouser, 2012, Antimicrobial Agents and Chemotherapy.

Ehrlichia Isolate from a Minnesota Tick: Characterization and Genetic Transformation

R. Felsheim, M. G. O’Sullivan, U. Munderloh, 2019, Applied and Environmental Microbiology.

Prenatal toxicity and lack of carcinogenicity of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) following transplacental exposure.

A. Townsend, M. Miller, K. M. Gressani, 2000, Toxicological sciences : an official journal of the Society of Toxicology.

Examination of a blood-brain barrier targeting β-galactosidase-monoclonal antibody fusion protein in a murine model of GM1-gangliosidosis

M. G. O’Sullivan, C. Whitley, R. Sidhu, 2021, Molecular genetics and metabolism reports.

Revised guides for organ sampling and trimming in rats and mice--Part 2. A joint publication of the RITA and NACAD groups.

Christine Ruehl-Fehlert, Birgit Kittel, Daniel R Roth, 2004, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria.

Elizabeth A Ambrose, E. Petricoin, Dafydd G. Thomas, 2017, Cell chemical biology.

Localized histiocytic sarcoma in a captive capybara (Hydrochoerus hydrochaeris)

M. G. O’Sullivan, S. Srivorakul, K. Boonsri, 2017 .

Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation.

C. S. Raymond, D. Zarkower, M. G. O’Sullivan, 2000, Genes & development.

Diffusion Limited Cryopreservation of Tissue with Radiofrequency Heated Metal Forms

J. Bischof, M. G. O’Sullivan, Zhe Gao, 2020, Advanced healthcare materials.

Oligodendroglioma with Neuronal Differentiation in Two Boxer Dogs.

M. G. O’Sullivan, H. Clark, I. Cornax, 2019, Journal of comparative pathology.

A Revised Diagnostic Classification of Canine Glioma: Towards Validation of the Canine Glioma Patient as a Naturally Occurring Preclinical Model for Human Glioma

D. Brat, K. Aldape, C. Miller, 2018, Journal of neuropathology and experimental neurology.

Mutagenicity of furan in female Big Blue B6C3F1 mice.

M. G. O’Sullivan, L. Peterson, J. Guttenplan, 2014, Mutation research. Genetic toxicology and environmental mutagenesis.

Eradication of Canine Diffuse Large B-Cell Lymphoma in a Murine Xenograft Model with CD47 Blockade and Anti-CD20

I. Weissman, A. Barkal, J. Modiano, 2016, Cancer Immunology Research.

Senolytics reduce coronavirus-related mortality in old mice

N. LeBrasseur, S. Khosla, S. Jameson, 2021, Science.

Fatal Disseminated Cercopithecine Herpesvirus 1 (Herpes B) Infection in Cynomolgus Monkeys {Macaca fascicularis)

M. G. O’Sullivan, D. Anderson, W. Jerome, 1997, Veterinary pathology.

Localized Retroperitoneal Fibromatosis Causing Intestinal Obstruction in a Cynomolgus Monkey (Macaca fascicularis)

J. Fikes, M. G. O’Sullivan, 1995, Veterinary pathology.

An In Vivo Immunotherapy Screen of Costimulatory Molecules Identifies Fc-OX40L as a Potent Reagent for the Treatment of Established Murine Gliomas

Flavia E. Popescu, M. G. O’Sullivan, A. Epstein, 2012, Clinical Cancer Research.

The role of KCNQ1 in mouse and human gastrointestinal cancers

D. Largaespada, G. Meijer, T. Starr, 2013, Oncogene.

A Sleeping Beauty transposon-mediated screen identifies murine susceptibility genes for adenomatous polyposis coli (Apc)-dependent intestinal tumorigenesis

D. Largaespada, T. Starr, A. Sarver, 2011, Proceedings of the National Academy of Sciences.

Dihydromethysticin from kava blocks tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis and differentially reduces DNA damage in A/J mice.

S. Hecht, M. G. O’Sullivan, S. Balbo, 2014, Carcinogenesis.

Kava Blocks 4-(Methylnitrosamino)-1-(3-pyridyl)-1-Butanone–Induced Lung Tumorigenesis in Association with Reducing O6-methylguanine DNA Adduct in A/J Mice

S. Hecht, M. G. O’Sullivan, S. Balbo, 2014, Cancer Prevention Research.

Gastric Infarction in Cynomolgus Monkeys (Macaca fascicularis)

J. Fikes, M. G. O’Sullivan, C. Carlson, 1996, Veterinary pathology.

Oral dosing of dihydromethysticin ahead of tobacco carcinogen NNK effectively prevents lung tumorigenesis in A/J mice.

S. Hecht, M. G. O’Sullivan, P. Upadhyaya, 2020, Chemical research in toxicology.

Heterotypic mouse models of canine osteosarcoma recapitulate tumor heterogeneity and biological behavior

Subbaya Subramanian, J. Modiano, B. Bryan, 2016, Disease Models & Mechanisms.

Transcriptional and Functional Activity of Canine Hemangiosarcoma to Support

Ashley J. Schulte, K. Lindblad-Toh, M. Meyerson, 2021 .

Aberrant Retinoblastoma (RB)-E2F Transcriptional Regulation Defines Molecular Phenotypes of Osteosarcoma*

Jyotika Varshney, Aaron L. Sarver, J. V. Van Etten, 2015, The Journal of Biological Chemistry.

CFTR is a tumor suppressor gene in murine and human intestinal cancer.

C. Hodges, D. Largaespada, G. Meijer, 2016, Oncogene.

Uterine Infarctions in Cynomolgus Monkeys (Macaca fascicularis)

J. Fikes, M. G. O’Sullivan, J. Cline, 2007, Veterinary pathology.

Comprehensive behavioral and biochemical outcomes of novel murine models of GM1-gangliosidosis and Morquio syndrome type B.

D. Ory, M. G. O’Sullivan, C. Whitley, 2019, Molecular genetics and metabolism.

Experimental evaluation of Peromyscus leucopus as a reservoir host of the Ehrlichia muris-like agent

M. G. O’Sullivan, U. Munderloh, I. Cornax, 2017, Parasites & Vectors.

Comparison of the Transcription Profile of Simian Parvovirus with That of the Human Erythrovirus B19 Reveals a Number of Unique Features

M. G. O’Sullivan, J. Qiu, D. Pintel, 2004, Journal of Virology.

Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma

David J. Odde, Jyotika Varshney, David A. Largaespada, 2016, Scientific Reports.

Experimental infection of cynomolgus monkeys with simian parvovirus

N. Young, M. G. O’Sullivan, D. Anderson, 1997, Journal of virology.

Prognostic histopathologic features of canine glial tumors

G. Pluhar, M. G. O’Sullivan, A. Rendahl, 2021, Veterinary pathology.

(S)-N'-Nitrosonornicotine, a constituent of smokeless tobacco, is a powerful oral cavity carcinogen in rats.

S. Hecht, M. G. O’Sullivan, S. Balbo, 2013, Carcinogenesis.

Canine intracranial gliomas: relationship between magnetic resonance imaging criteria and tumor type and grade.

M. Miller, C. Ober, M. G. O’Sullivan, 2013, Veterinary journal.

Reduction in Colon Cancer Risk by Consumption of Kava or Kava Fractions in Carcinogen-Treated Rats

M. G. O’Sullivan, D. Gallaher, Ahmad Ali Shaik, 2012, Nutrition and cancer.

Gene expression signatures associated with suppression of TRAMP prostate carcinogenesis by a kavalactone‐rich Kava fraction

Cheng Jiang, J. Lü, M. G. O’Sullivan, 2016, Molecular carcinogenesis.

A Highly Efficacious PS Gene Editing System Corrects Metabolic and Neurological Complications of Mucopolysaccharidosis Type I.

M. G. O’Sullivan, C. Whitley, Sarah Kim, 2020, Molecular therapy : the journal of the American Society of Gene Therapy.

Meningioma with rhabdoid features: Pathologic findings in dogs

G. Pluhar, M. G. O’Sullivan, A. Armién, 2022, Veterinary pathology.

Evolution to Pathogenicity of the Parvovirus Minute Virus of Mice in Immunodeficient Mice Involves Genetic Heterogeneity at the Capsid Domain That Determines Tropism

J. Segovia, J. Bueren, M. G. O’Sullivan, 2007, Journal of Virology.

CFTR is a tumor suppressor gene in murine and human intestinal cancer

C. Hodges, D. Largaespada, G. Meijer, 2016, Oncogene.

Intrahepatic cholangiocarcinoma in a captive meerkat (Suricata suricatta).

M. G. O’Sullivan, K. Boonsri, K. Pringproa, 2013, Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians.

INTRAHEPATIC CHOLANGIOCARCINOMA IN A CAPTIVE MEERKAT (SURICATA SURICATTA)

M. G. O’Sullivan, K. Boonsri, K. Pringproa, 2013 .

A novel cancer syndrome caused by KCNQ1-deficiency in the golden Syrian hamster

M. G. O’Sullivan, R. Cormier, Zhongde Wang, 2018, Journal of carcinogenesis.

Fixed-Dose Combinations of Pioglitazone and Metformin for Lung Cancer Prevention

V. Steele, F. Ondrey, M. G. O’Sullivan, 2017, Cancer Prevention Research.

Colonic adenocarcinoma in rhesus macaques.

M. G. O’Sullivan, C. Carlson, 2001, Journal of comparative pathology.

Pilot in Vivo Structure-Activity Relationship of Dihydromethysticin in Blocking 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-Induced O6-Methylguanine and Lung Tumor in A/J Mice.

Haifeng Sun, S. Hecht, M. G. O’Sullivan, 2017, Journal of medicinal chemistry.

Carcinogenicity and DNA adduct formation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F-344 rats.

S. Hecht, M. G. O’Sullivan, S. Balbo, 2014, Carcinogenesis.