A. Theofilopoulos

R. Lerner, A. Theofilopoulos, Yingjie Peng, 2016, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Genetic contributions to SLE.

D. Kono, A. Theofilopoulos, 1996, Journal of autoimmunity.

Etiopathogenesis of Murine SLE 1

A. Theofilopoulos, F. Dixon, 1981 .

T cell receptor biases and clonal proliferations among lung transplant recipients with obliterative bronchiolitis.

A. Theofilopoulos, V. Valentine, D. Kono, 1996, The Journal of clinical investigation.

Sequence of I-E genes from autoimmune New Zealand white mice.

L. Smith, A. Theofilopoulos, 1990, Arthritis and rheumatism.

Detection of circulating immune complexes in patients with glomerulonephritis.

O. Götze, A. Theofilopoulos, A. Woodroffe, 1977, Kidney international.

IgM rheumatoid factor and low molecular weight IgM. An association with vasculitis.

A. Theofilopoulos, G. Burtonboy, M. Ziff, 1974, Arthritis and rheumatism.

Autoimmune diseases: immunopathology and etiopathogenesis.

A. Theofilopoulos, F. Dixon, 1982, The American journal of pathology.

The Biology of Immune Complexes and Their Possible Role in Pregnancy *

A. Theofilopoulos, N. Gleicher, F. Dixon, 1981, American journal of reproductive immunology : AJRI : official journal of the American Society for the Immunology of Reproduction and the International Coordination Committee for Immunology of Reproduction.

TLRs and IFNs: critical pieces of the autoimmunity puzzle.

A. Theofilopoulos, 2012, The Journal of clinical investigation.

Inhibition of Lupus by Genetic Alteration of the Interferon-α/β Receptor

D. Kono, A. Theofilopoulos, R. Baccala, 2003 .

This information is current as Response to a Single Viral Epitope Polyclonality and Multispecificity of the CTL

F. Chisari, T. Ishikawa, A. Theofilopoulos, 1998 .

Oligoclonal CD4(+) T cell expansions in lung transplant recipients with obliterative bronchiolitis.

G. Rosen, A. Theofilopoulos, J. Theodore, 2002, American journal of respiratory and critical care medicine.

The role of IFN-γ in systemic lupus erythematosus : a challenge to the Th 1 / Th 2 paradigm in autoimmunity

D. Kono, A. Theofilopoulos, B. Lawson, 2015 .

Clonal characteristics of T cell infiltrates in skin and synovium of patients with psoriatic arthritis.

M. Centola, A. Theofilopoulos, D. Boumpas, 1999, Human immunology.

Association of lpr gene with graft-vs.-host disease-like syndrome

R. Balderas, A. Theofilopoulos, Y. Gozes, 1985, The Journal of experimental medicine.

Anti–IFN-α/β Receptor Antibody Treatment Ameliorates Disease in Lupus-Predisposed Mice

R. Schreiber, D. Kono, A. Theofilopoulos, 2012, The Journal of Immunology.

Genes and genetics of murine systemic lupus erythematosus

D. Kono, A. Theofilopoulos, 2021, Systemic Lupus Erythematosus.

Characterization of Reciprocal Lmb1–4 Interval MRL-Faslpr and C57BL/6-Faslpr Congenic Mice Reveals Significant Effects from Lmb31

D. Kono, A. Theofilopoulos, M. Santiago‐Raber, 2007, The Journal of Immunology.

Intrathymic injection of polynucleosomes delays autoantibody production in BXSB mice.

A. Theofilopoulos, R. Burlingame, S. Duncan, 1996, Clinical immunology and immunopathology.

Induction of severe autoimmune disease in normal mice by simultaneous action of multiple immunostimulators

A. Theofilopoulos, F. Dixon, L. Hang, 1985, The Journal of experimental medicine.

Treatment of murine lupus with cDNA encoding IFN-gammaR/Fc.

D. Kono, A. Theofilopoulos, G. Prud’homme, 2000, The Journal of clinical investigation.

The solute carrier SLC15A4 is required for optimal trafficking of nucleic acid–sensing TLRs and ligands to endolysosomes

B. Beutler, I. Rimann, W. Kiosses, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Multiple autoantigen binding capabilities of mouse monoclonal antibodies selected for rheumatoid factor activity

R. Balderas, E. Tan, A. Theofilopoulos, 1984, The Journal of experimental medicine.

Evidence for the presence of receptors for C3 and IgG Fc on human synovial cells.

A. Theofilopoulos, D. Carson, S. Slovin, 1980, Arthritis and rheumatism.

Isolation of human T and B lymphocytes by rosette formation with 2-aminoethylisothiquronium bromide (AET) -treated sheep red blood cells with monkey red blood cells.

S. Ferrone, A. Theofilopoulos, M. Pellegrino, 1976, Journal of immunological methods.

Coding sequence polymorphisms among V beta T cell receptor genes.

L. Smith, A. Theofilopoulos, P. Singer, 1990, Journal of immunology.

T-cell receptor alpha-chain variable-region haplotypes of normal and autoimmune laboratory mouse strains.

R. Balderas, A. Theofilopoulos, R. McEvilly, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Genetics of systemic autoimmunity and glomerulonephritis in mouse models of lupus.

D. Kono, A. Theofilopoulos, 2001, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

The nature of immune complexes in human cancer sera.

D. Morton, A. Theofilopoulos, B. S. Andrews, 1977, Journal of immunology.

Influence of thymic genotype on the systemic lupus erythematosus-like disease and T cell proliferation of MRL/Mp-lpr/lpr mice

R. Balderas, A. Theofilopoulos, D. Shawler, 1981, The Journal of experimental medicine.

A comparative immunologic analysis of several murine strains with autoimmune manifestations.

A. Theofilopoulos, W. D. Creighton, R. Eisenberg, 1980, Clinical immunology and immunopathology.

Development of Lupus in BXSB Mice Is Independent of IL-41

D. Balomenos, D. Kono, A. Theofilopoulos, 2000, The Journal of Immunology.

Independent of IL-4 Development of Lupus in BXSB Mice Is

D. Balomenos, D. Kono, A. Theofilopoulos, 1999 .

Proliferative arrest and cell cycle regulation in CD8(+)CD28(-) versus CD8(+)CD28(+) T cells.

H. Sabzevari, A. Theofilopoulos, U. Scheuring, 2002, Human immunology.

Ig heavy chain variable region gene complex of lupus mice exhibits normal restriction fragment length polymorphism

R. Perlmutter, R. Kofler, D. Noonan, 1985, The Journal of experimental medicine.

Monoclonal antibodies against complement 3 neoantigens for detection of immune complexes and complement activation. Relationship between immune complex levels, state of C3, and numbers of receptors for C3b.

J. Lambris, A. Theofilopoulos, D. Bitter‐Suermann, 1985, The Journal of clinical investigation.

Immune Complexes in Human and Experimental Disease

A. Theofilopoulos, M. Aguado, 1985 .

Lack of Intrinsic CTLA-4 Expression Has Minimal Effect on Regulation of Antiviral T-Cell Immunity

A. Theofilopoulos, M. V. von Herrath, M. Oldstone, 2006, Journal of Virology.

Vβ repertoire in rats and implications for endogenous superantigens

R. Balderas, D. Kono, A. Theofilopoulos, 1992 .

Use of circulating immune complex levels in the serodifferentiation of endocarditic and nonendocarditic septicemias.

D. Tillman, A. Theofilopoulos, A. Bayer, 1979, The American journal of medicine.

Circulating immune complexes in infective endocarditis.

A. Theofilopoulos, A. Bayer, L. B. Guze, 1976, The New England journal of medicine.

CIRCULATING IMMUNE COMPLEXES IN MULTIPLE SCLEROSIS AND OTHER NEUROLOGICAL DISEASES

A. Theofilopoulos, H. Koprowski, R. Lisak, 1976, The Lancet.

T-cell receptor a-chain variable-region haplotypes ofnormaland autoimmune laboratory mousestrains (T-celi repertoire/imRNA expression/RNase protection assay/murine lupus/NOD mouse)

R. Balderas, A. Theofilopoulos, R. McEvilly, 1988 .

Presence of circulating immune complexes in Reiter's syndrome and ankylosing spondylitis

A. Calin, H. Mcdevitt, A. Theofilopoulos, 1981 .

Novel origin of lpr and gld cells and possible implications in autoimmunity.

A. Theofilopoulos, P. Singer, Argyrios N. Theofilopoulos, 1990, Journal of autoimmunity.

Histidine-Rich Glycoprotein Binds to DNA and FcγRI and Potentiates the Ingestion of Apoptotic Cells by Macrophages1

Brian A. Smith, D. Kono, A. Theofilopoulos, 2002, The Journal of Immunology.

Apoptotic Cells by Macrophages RI and Potentiates the Ingestion of γ and Fc Histidine-Rich Glycoprotein Binds to DNA

Brian A. Smith, D. Kono, A. Theofilopoulos, 2002 .

Interferon-g is Required for Lupus-like Disease and Lymphoaccumulation in MRL-lpr Mice

D. Balomenos, A. Theofilopoulos, R. Rumold, 2022 .

T‐Cell Repertoires in Health and Disease a

R. Balderas, D. Kono, A. Theofilopoulos, 1995, Annals of the New York Academy of Sciences.

Demonstration of circulating immune complexes in Sjögren's syndrome.

A. Theofilopoulos, M. Frank, H. Moutsopoulos, 1979, Journal of immunology.

Macrophage I-A/I-E expression and macrophage-stimulating lymphokines in murine lupus.

R. Schreiber, R. Kofler, A. Theofilopoulos, 1984, Cellular immunology.

Metabolism of autologous and homologous IgG in rheumatoid arthritis.

A. Theofilopoulos, R. Nakamura, J. Vaughan, 1977, The Journal of clinical investigation.

R. Balderas, A. Theofilopoulos, M. Bobardt, 1989, The Journal of experimental medicine.

Immune complexes in hepatitis B antigen-associated periarteritis nodosa. Detection by antibody-dependent cell-mediated cytotoxicity and the Raji cell assay.

A. Theofilopoulos, H. Moutsopoulos, N. Talal, 1977, The American journal of medicine.

Anticytokine gene therapy of autoimmune diseases

A. Theofilopoulos, G. Prud’homme, B. Lawson, 2001, Expert opinion on biological therapy.

Replication of dengue-2 virus in cultured human lymphoblastoid cells and subpopulations of human peripheral leukocytes.

A. Theofilopoulos, W. Brandt, P. Russell, 1976, Journal of immunology.

New human V beta genes and polymorphic variants.

D. Kono, A. Theofilopoulos, A. Plaza, 1991, Journal of immunology.

R. Balderas, A. Theofilopoulos, M. Bobardt, 2003 .

Molecular aspects of autoimmunity.

R. Kofler, A. Theofilopoulos, 1989, Immunology today.

The Lbw2 Locus Promotes Autoimmune Hemolytic Anemia

John C. Scatizzi, D. Kono, A. Theofilopoulos, 2012, The Journal of Immunology.

Hemolytic Anemia Locus Promotes Autoimmune Lbw2 The

John C. Scatizzi, D. Kono, A. Theofilopoulos, 2022 .

Thymic selection defines multiple T cell receptor V beta ‘repertoire phenotypes’ at the CD4/CD8 subset level.

R. Balderas, A. Theofilopoulos, A. Theofilopoulos, 1990, The EMBO journal.

Genetics of systemic autoimmunity.

A. Theofilopoulos, 1996, Journal of autoimmunity.

Clonal diversity and T-cell receptor beta-chain variable gene expression in enlarged lymph nodes of MRL-lpr/lpr lupus mice.

D. Noonan, A. Theofilopoulos, R. McEvilly, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Type I interferon is a therapeutic target for virus-induced lethal vascular damage

C. Ng, A. Theofilopoulos, J. C. de la Torre, 2014, Proceedings of the National Academy of Sciences.

Protection T Cell-Mediated Antiviral + for CD4 Qualitative and Quantitative Requirements

H. Pircher, R. Zinkernagel, U. Hoffmann‐Rohrer, 1999 .

V beta repertoire in rats and implications for endogenous superantigens.

R. Balderas, L. Smith, D. Kono, 1992, European journal of immunology.

Identification of a B cell differentiation factor(s) spontaneously produced by proliferating T cells in murine lupus strains of the lpr/lpr genotype

R. Kofler, A. Theofilopoulos, T. M. Fieser, 1983, The Journal of experimental medicine.

Etiopathogenesis of murine SLE.

A. Theofilopoulos, F. Dixon, 1981, Immunological reviews.

Monoclonal autoantibodies reacting with multiple structurally related and unrelated macromolecules.

A. Theofilopoulos, R. Rubin, 1988, International reviews of immunology.

Analysis of T cell function in autoimmune murine strains. Defects in production and responsiveness to interleukin 2

D. Katz, A. Altman, A. Theofilopoulos, 1981, The Journal of experimental medicine.

Experimental models for systemic autoimmune disease—Current concepts

A. Theofilopoulos, M. Aguado, 1985 .

B-cell hyperactivity in murine lupus II. Defects in response to and production of accessory signals in lupus-prone mice.

A. Theofilopoulos, T. M. Fieser, G. Prud’homme, 1983, Immunology today.

B cell dependence on and response to accessory signals in murine lupus strains

R. Balderas, A. Theofilopoulos, G. Prud’homme, 1983, The Journal of experimental medicine.

Role of the thymus in murine lupus and cellular transfer of the disease.

A. Theofilopoulos, 1982, Arthritis and rheumatism.

Surface and functional characteristics of B cells from lupus-prone murine strains.

R. Balderas, A. Ahmed, A. Theofilopoulos, 1982, Clinical immunology and immunopathology.

Production of interleukin 2 (IL 2) by salivary gland lymphocytes in Sjögren's syndrome. Detection of reactive cells by using antibody directed to synthetic peptides of IL 2.

A. Altman, A. Theofilopoulos, R. Fox, 1985, Journal of immunology.

Isolation of circulating immune complexes using Raji cells. Separation of antigens from immune complexes and production of antiserum.

A. Theofilopoulos, R. Eisenberg, F. Dixon, 1978, The Journal of clinical investigation.

Pulmonary immune complex deposition in Wegener's granulomatosis.

A. Theofilopoulos, M. Schwarz, D. Shasby, 1982, Chest.

Isotypic profiles and other fine characteristics of immune responses to exogenous thymus-dependent and -independent antigens by mice with lupus syndromes.

R. Balderas, A. Theofilopoulos, T. M. Fieser, 1983, Journal of immunology.

Thrombotic thrombocytopenic purpura-like syndrome associated with infective endocarditis. A possible immune complex disorder.

A. Theofilopoulos, A. Bayer, L. B. Guze, 1977, JAMA.

The biology and detection of immune complexes.

A. Theofilopoulos, F. Dixon, A N Theofilopoulos, 1979, Advances in immunology.

Thymic dendritic cells traffic to thymi of allogeneic recipients and prolong graft survival.

A. Theofilopoulos, Steven R Duncan, Brian R Lawson, 2002, The Journal of clinical investigation.

Murine SLE - aetiology and pathogenesis.

A. Theofilopoulos, S. Izui, F. Dixon, 1980 .

The Raji cell radioimmune assay for detecting immune complexes in human sera.

A. Theofilopoulos, C. Wilson, F. Dixon, 1976, The Journal of clinical investigation.

TYPE I INTERFERONS (/) IN IMMUNITY AND AUTOIMMUNITY

B. Beutler, D. Kono, A. Theofilopoulos, 2005 .

Type I interferons (alpha/beta) in immunity and autoimmunity.

B. Beutler, D. Kono, A. Theofilopoulos, 2005, Annual review of immunology.

BINDING OF SOLUBLE IMMUNE COMPLEXES TO HUMAN LYMPHOBLASTOID CELLS

A. Theofilopoulos, F. Dixon, V. Bokisch, 1974, The Journal of experimental medicine.

T-cell receptor biases and clonal proliferations in blood and pleural effusions of patients with lung cancer.

A. Theofilopoulos, S. Duncan, M. Roglić, 1997, Human immunology.

The basis of autoimmunity: Part I. Mechanisms of aberrant self-recognition.

A. Theofilopoulos, 1995, Immunology today.

Circulating immune complexes as possible cause for anticomplementary activity in humans with malignant melanoma

R. Gupta, D. Morton, A. Theofilopoulos, 1979, Cancer Immunology, Immunotherapy.

Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes

A. Theofilopoulos, R. Eisenberg, F. Dixon, 1979, The Journal of experimental medicine.

BINDING OF SOLUBLE IMMUNE COMPLEXES TO HUMAN LYMPHOBLASTOID CELLS

A. Theofilopoulos, F. Dixon, V. Bokisch, 1974, The Journal of experimental medicine.

The genetic origin of autoantibodies.

R. Kofler, A. Theofilopoulos, F. Dixon, 1987, Immunology today.

Qualitative and quantitative requirements for CD4+ T cell-mediated antiviral protection.

H. Pircher, R. Zinkernagel, U. Hoffmann‐Rohrer, 1999, Journal of immunology.

Section Reviews: Biologicals & Immunologicals: Sjögren's syndrome: Pathogenesis and prospects for therapy

A. Theofilopoulos, R. Fox, 1996 .

Genetic studies of autoimmunity and retrovirus expression in crosses of New Zealand black mice. II. The viral envelope glycoprotein gp70

R. Schwartz, A. Theofilopoulos, S. Datta, 1978, The Journal of experimental medicine.

Lack of relationship between serum gp70 levels and the severity of systemic lupus erythematosus in MRL/l mice

A. Theofilopoulos, F. Dixon, J. Andrews, 1986, The Journal of experimental medicine.

Type-I Interferon Receptor Deficiency Reduces Lupus-like Disease in NZB Mice

D. Choubey, D. Kono, A. Theofilopoulos, 2003, The Journal of experimental medicine.

Complexes with murine systemic lupus erythematosus.

A. Theofilopoulos, S. Izui, P. McConahey, 1979 .

Distribution of lymphocytes identified by surface markers in murine strains with sle-like syndromes. Abstr.

A. Theofilopoulos, R. Eisenberg, F. Dixon, 1979 .

Use of bovine conglutinin for the assay of immune complexes.

A. Theofilopoulos, R. Eisenberg, F. Dixon, 1977, Journal of immunology.

IMMUNE COMPLEXES IN PREGNANCY

A. Theofilopoulos, N. Gleicher, 1978, The Lancet.

V beta gene repertoires in aging mice.

A. Theofilopoulos, R. Gonzalez‐Quintial, R. González‐Quintial, 1992, Journal of immunology.

Immunogene Therapy with Nonviral Vectors

A. Theofilopoulos, C. Piccirillo, G. Prud’homme, 2005 .

Polyclonality and multispecificity of the CTL response to a single viral epitope.

F. Chisari, T. Ishikawa, J. Chung, 1998, Journal of immunology.

Vβ Gene Repertoire in the Aging Mouse: A Developmental Perspective

R. Balderas, A. Theofilopoulos, R. Baccala, 1995 .

Quantitation of circulating immune complexes, immunoglobulins G and M, and C3 complement component in patients with large periapical lesions.

M. Torabinejad, A. Theofilopoulos, L. Bakland, 1983, Oral surgery, oral medicine, and oral pathology.

Yip1 domain family, member 6 (Yipf6) mutation induces spontaneous intestinal inflammation in mice

B. Beutler, W. Falk, A. Theofilopoulos, 2012, Proceedings of the National Academy of Sciences.

8 – GENES AND GENETICS OF MURINE LUPUS

D. Kono, A. Theofilopoulos, R. Baccala, 2004 .

Suggestive evidence for association of human chromosome 18q12-q21 and its orthologue on rat and mouse chromosome 18 with several autoimmune diseases.

J. Todd, Paul Wordsworth, S. Sawcer, 2001, Diabetes.

The basis of autoimmunity: Part II. Genetic predisposition.

A. Theofilopoulos, 1995, Immunology today.

Genetic susceptibility to spontaneous lupus in mice.

D. Kono, A. Theofilopoulos, 1999, Current directions in autoimmunity.

Antigen receptor genes in autoimmune B and T cells.

R. Kofler, A. Theofilopoulos, P. Singer, 1988, Scandinavian journal of rheumatology. Supplement.

Role of Cyclin Kinase Inhibitor p21 in Systemic Autoimmunity1 2

D. Kono, A. Theofilopoulos, W. Dummer, 2001, The Journal of Immunology.

Inhibition of Transmethylation Down-Regulates CD4 T Cell Activation and Curtails Development of Autoimmunity in a Model System

Brian R. Lawson, A. Theofilopoulos, Yulia Manenkova, 2007, The Journal of Immunology.

Interferons as pathogenic effectors in autoimmunity

D. Kono, A. Theofilopoulos, R. Baccala, 2005, Immunological reviews.

Sensors of the innate immune system: their mode of action

B. Beutler, D. Kono, A. Theofilopoulos, 2009, Nature Reviews Rheumatology.

Mechanisms and Genetics of Autoimmunity a

D. Kono, A. Theofilopoulos, 1998 .

Delineation of a defect in T cell receptor beta genes of NZW mice predisposed to autoimmunity

R. Kofler, D. Noonan, A. Theofilopoulos, 1986, The Journal of experimental medicine.

T cell homeostasis and systemic autoimmunity.

D. Kono, A. Theofilopoulos, W. Dummer, 2001, The Journal of clinical investigation.

Immune complexes in human diseases: a review.

A. Theofilopoulos, F. Dixon, 1980, The American journal of pathology.

Detection and partial characterization of circulating immune complexes with solid-phase anti-C3.

A. Theofilopoulos, A. B. Pereira, F. Dixon, 1980, Journal of immunology.

Analysis of pancreas-infiltrating T cells in diabetic NOD mice: fusion with BW5147 yields a high frequency of islet-reactive hybridomas.

R. Balderas, A. Theofilopoulos, G. Prud’homme, 1991, Autoimmunity.

T‐Cell Receptor Genes in Autoimmunity a

R. Balderas, D. Kono, A. Theofilopoulos, 1993, Annals of the New York Academy of Sciences.

T‐Cell Receptor Vβ Repertoire Expression in Murine Models of SLE

A. Theofilopoulos, P. Singer, 1990, Immunological reviews.

Intracellular nucleic acid sensors and autoimmunity.

B. Beutler, D. Kono, A. Theofilopoulos, 2011, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

The multiple pathways to autoimmunity

D. Kono, A. Theofilopoulos, R. Baccala, 2017, Nature Immunology.

Terminal Deoxynucleotidyltransferase Deficiency Decreases Autoimmune Disease in Diabetes-Prone Nonobese Diabetic Mice and Lupus-Prone MRL-Faslpr Mice1

A. Feeney, N. Sarvetnick, D. Kono, 2004, The Journal of Immunology.

Immunoglobulin kappa light chain variable region gene complex organization and immunoglobulin genes encoding anti-DNA autoantibodies in lupus mice.

R. Balderas, R. Kofler, D. Noonan, 1988, The Journal of clinical investigation.

Chapter 19 – Autoimmunity

D. Kono, A. Theofilopoulos, 2017 .

Tumour necrosis factor and other cytokines in murine lupus

A. Theofilopoulos, B. Lawson, 1999, Annals of the rheumatic diseases.

Lysis of human cultured lymphoblastoid cells by cell-induced activation of the properdin pathway.

A. Theofilopoulos, L. Perrin, 1977, Science.

Transmethylation in immunity and autoimmunity.

T. Eleftheriadis, D. Kono, A. Theofilopoulos, 2012, Clinical immunology.

Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen.

R. Balderas, A. Theofilopoulos, R. Burlingame, 1993, The Journal of clinical investigation.

Genetic elements used for a murine lupus anti-DNA autoantibody are closely related to those for antibodies to exogenous antigens

D. Levy, R. Kofler, D. Noonan, 1985, The Journal of experimental medicine.

Monoclonal IgM rheumatoid factors derived from arthritic MRL/Mp-lpr/lpr mice

R. Balderas, A. Theofilopoulos, F. Dixon, 1983, The Journal of experimental medicine.

The Raji, conglutinin, and anti-C3 assays for the detection of complement-fixing immune complexes.

A. Theofilopoulos, 1981, Methods in enzymology.

Evaluation and clinical significance of circulating immune complexes.

A. Theofilopoulos, 1980, Progress in clinical immunology.

Molecular genetics of murine lupus

A. Theofilopoulos, 1986, Agents and Actions.

Immune complexes in humoral immune responses: suppressive and enhancing effects.

A. Theofilopoulos, 1980, Immunology today.

Tumor immunity via homeostatic T cell proliferation: mechanistic aspects and clinical perspectives

A. Theofilopoulos, R. Baccala, W. Dummer, 2005, Springer Seminars in Immunopathology.

Inhibition of T cells proliferation and SLE-like syndrome of MRL/1 mice by whole body or total lymphoid irradiation.

R. Balderas, A. Theofilopoulos, S. Strober, 1980, Journal of immunology.

Commitment to the Regulatory T Cell Lineage Requires CARMA1 in the Thymus but Not in the Periphery

B. Beutler, P. Krebs, A. Theofilopoulos, 2009, PLoS biology.

Loci predisposing to autoimmunity in MRL-Fas lpr and C57BL/6-Faslpr mice.

D. Kono, A. Theofilopoulos, S. Vidal, 1998, The Journal of clinical investigation.

Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger

B. Beutler, A. Theofilopoulos, S. Pettersson, 2008, Proceedings of the National Academy of Sciences.

T cell homeostatic proliferation elicits effective antitumor autoimmunity.

A. Theofilopoulos, R. Reisfeld, R. Baccala, 2002, The Journal of clinical investigation.

Lupus acceleration by a MAVS-activating RNA virus requires endosomal TLR signaling and host genetic predisposition

D. Kono, A. Theofilopoulos, M. Oldstone, 2018, PloS one.

Immune complexes in infective endocarditis

A. Theofilopoulos, A. Bayer, 2004, Springer Seminars in Immunopathology.

Immunopathogenetic aspects of infective endocarditis.

A. Theofilopoulos, A. Bayer, Argyrios N. Theofilopoulos, 1990, Chest.

Rosette formation of human lymphoid cells with monkey red blood cells.

S. Ferrone, A. Theofilopoulos, M. Pellegrino, 1975, Journal of immunology.

Polynucleotide specificities of murine monoclonal anti-DNA antibodies.

E. Tan, A. Theofilopoulos, K. Pollard, 1986, Clinical immunology and immunopathology.

Autoimmune aspects of systemic lupus erythematosus.

A. Theofilopoulos, G. Prud’homme, F. Dixon, 1985, Concepts in immunopathology.

Genetics of Lupus in Mice

D. Kono, A. Theofilopoulos, 2011 .

B and T Cell antigen receptor repertoires in lupus/arthritis murine models

R. Balderas, R. Kofler, D. Kono, 2004, Springer Seminars in Immunopathology.

Terminal Deoxynucleotidyl Transferase Deficiency Decreases Autoimmune Disease in MRL-Faslpr Mice1 2

A. Feeney, D. Kono, A. Theofilopoulos, 2001, The Journal of Immunology.

MRL-Deficiency Decreases Autoimmune Disease in Terminal Deoxynucleotidyl Transferase

A. Feeney, D. Kono, A. Theofilopoulos, 2001 .

Immune Monitoring Protocol for Patients with Carcinoma of the Head and Neck

A. Theofilopoulos, R. Veltri, S. Rodman, 1978, The Annals of otology, rhinology, and laryngology.

TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity

B. Beutler, D. Kono, A. Theofilopoulos, 2007, Nature Medicine.

Essential requirement for IRF8 and SLC15A4 implicates plasmacytoid dendritic cells in the pathogenesis of lupus

B. Beutler, K. Ozato, I. Rimann, 2013, Proceedings of the National Academy of Sciences.

Immune complexes (ICs) and pregnancy. Pregnancy as an IC-state or IC-disease and the influence of IC-diseases on pregnancy.

A. Theofilopoulos, N. Gleicher, 1980, Diagnostic gynecology and obstetrics.

Increased expression of the FoxP3 functional marker of regulatory T cells following B cell depletion with rituximab in patients with lupus nephritis.

A. Theofilopoulos, P. Sfikakis, V. Souliotis, 2007, Clinical immunology.

Deficiency of the Cyclin Kinase Inhibitor p21(WAF-1/CIP-1) Promotes Apoptosis of Activated/Memory T Cells and Inhibits Spontaneous Systemic Autoimmunity

M. Croft, Jianxun Song, D. Kono, 2004, The Journal of experimental medicine.

Cloning and Sequencing of Murine Lupus-Associated Autoantibody Genes

G. Kroemer, R. Kofler, D. Noonan, 1988 .

Mycoplasma arthritidis mitogen. Vβ engaged in mice, rats, and humans, and requirement of HLA‐DRα for presentation

P. A. Peterson, A. Theofilopoulos, R. Baccala, 1992 .

Patterns of immune reactivity in autoimmune murine strains. I. Cell-mediated immune responses induced by H-2 indentical and H-2 incompatible stimulator cells.

D. Katz, A. Theofilopoulos, D. Shawler, 1979, Journal of immunology.

Specificity and molecular characteristics of monoclonal IgM rheumatoid factors from arthritic and non-arthritic mice.

R. Balderas, R. Kofler, A. Theofilopoulos, 1987, Journal of immunology.

Induction of Systemic Autoimmunity by a Xenobiotic Requires Endosomal TLR Trafficking and Signaling from the Late Endosome and Endolysosome but Not Type I IFN

B. Beutler, D. Kono, A. Theofilopoulos, 2017, The Journal of Immunology.

Treatment of murine lupus with cDNA encoding IFN-γR/Fc

D. Kono, A. Theofilopoulos, G. Prud’homme, 2000 .

RECEPTOR FOR SOLUBLE C3 AND C3b ON HUMAN LYMPHOBLASTOID (RAJI) CELLS

A. Theofilopoulos, F. Dixon, V. Bokisch, 1974, The Journal of experimental medicine.

Report on international comparative evaluation of possible value of assays for immune complexes for diagnosis of human breast cancer

H. Luthra, A. Theofilopoulos, P. Lambert, 1981, International journal of cancer.

Immune complexes associated with neoplasia: presence of Epstein-Barr virus antigen-antibody complexes in Burkitt's lymphoma.

G. Klein, A. Theofilopoulos, M. Oldstone, 1974, Intervirology.

Autoimmune Alterations Induced by the New Zealand Black Lbw2 Locus in BWF1 Mice1

G. Gilkeson, D. Kono, A. Theofilopoulos, 2005, The Journal of Immunology.

Immune complexes in cancer.

A. Theofilopoulos, 1982, The New England journal of medicine.

Detection of immune complexes: techniques and implications.

A. Theofilopoulos, F. Dixon, 1980, Hospital practice.

Molecular aspects of murine systemic lupus erythematosus

R. Kofler, D. Noonan, A. Theofilopoulos, 2005, Springer Seminars in Immunopathology.

Molecular genetics of murine lupus models.

R. Kofler, A. Theofilopoulos, F. Dixon, 1989, Advances in immunology.

GENOMIC AND EXPRESSED T CELL ANTIGEN RECEPTOR REPERTOIRE IN AUTOIMMUNE MURINE MODELS1

A. Theofilopoulos, P. Singer, 1990 .

Tumor-targeted IL-2 amplifies T cell-mediated immune response induced by gene therapy with single-chain IL-12.

A. Theofilopoulos, S. Gillies, R. Xiang, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Deletion of IgG-Switched Autoreactive B Cells and Defects in Faslpr Lupus Mice

D. Nemazee, D. Kono, A. Theofilopoulos, 2010, The Journal of Immunology.

The molecular pathology of autoimmune diseases

Constantin A. Bona, C. Bona, A. Theofilopoulos, 2002 .

The role of alpha beta+ T cells and homeostatic T cell proliferation in Y-chromosome-associated murine lupus.

D. Kono, A. Theofilopoulos, R. Baccala, 2001, Journal of immunology.

Suppression of transferred BXSB male SLE disease by female spleen cells.

A. Theofilopoulos, S. Izui, F. Dixon, 1982, Journal of immunology.

Specificities of NZB anti-H-2d CML reactions: role of Qa-1 and retroviral gp70 antigens.

D. Katz, R. Balderas, A. Theofilopoulos, 1981, Journal of immunology.

The Role of αβ+ T Cells and Homeostatic T Cell Proliferation in Y-Chromosome-Associated Murine Lupus1

D. Kono, A. Theofilopoulos, R. Baccala, 2001, The Journal of Immunology.

An autosomal recessive gene that delays expression of lupus in BXSB mice.

R. Balderas, R. Kofler, A. Theofilopoulos, 1991, Journal of immunology.

I. Cell-mediated immune responses induced by h-2 identical and h-2 incompatible stimulator cells.

D. Katz, A. Theofilopoulos, D. Shawler, 1979 .

Etiology and pathogenesis of a spontaneous lupus-like syndrome in mice.

A. Theofilopoulos, B. S. Andrews, C. Wilson, 1978, Arthritis and rheumatism.

Systemic Lupus Erythematosus, Animal Models

A. Theofilopoulos, 1998 .

Molecular analysis of the murine lupus‐associated anti‐self response: involvement of a large number of heavy and light chain variable region genes

R. Balderas, R. Kofler, D. Noonan, 1987, European journal of immunology.

Thymic selection of the human T cell receptor V beta repertoire in SCID- hu mice

M. Roncarolo, A. Theofilopoulos, D. Kono, 1992, The Journal of experimental medicine.

Bacterial superantigens mediate T cell deletions in the mouse severe combined immunodeficiency-human liver/thymus model

M. Roncarolo, A. Theofilopoulos, D. Kono, 1993, Journal of Experimental Medicine.

IgG rheumatoid factor in subacute bacterial endocarditis: relationship to IgM rheumatoid factor and circulating immune complexes.

A. Theofilopoulos, D. Carson, A. Bayer, 1978, Clinical and experimental immunology.

Contribution of histidine-rich glycoprotein in clearance of immune complexes and apoptotic cells: Implications for ameliorating autoimmune diseases

A. Theofilopoulos, N. N. Gorgani, 2007, Autoimmunity.

Abrogation of murine lupus by the xid gene is associated with reduced responsiveness of B cells to T-cell-helper signals.

A. Steinberg, A. Theofilopoulos, M. Gershwin, 1984, Cellular immunology.

A microassay for the determination of hemolytic complement activity in mouse serum.

A. Theofilopoulos, B. S. Andrews, Argyrios N. Theofilopoulos, 1978, Journal of immunological methods.

Differential expression profiles of apoptosis-affecting genes in HIV-infected cell lines and patient T cells.

J. Corbeil, H. Sabzevari, A. Theofilopoulos, 1999, AIDS.

Neurological disease associated with Mycoplasma pneumoniae pneumonitis: demonstration of viable Mycoplasma pneumoniae in cerebrospinal fluid and blood by radioisotopic and immunofluorescent tissue culture techniques.

A. Theofilopoulos, A. Bayer, J. Galpin, 1981, Annals of internal medicine.

Circulating immune complexes in Takayasu disease.

A. Theofilopoulos, N. Talal, F. Numano, 1980, Japanese circulation journal.

Circulating immune complexes in experimental streptococcal endocarditis: a monitor of therapeutic efficacy.

A. Theofilopoulos, A. Bayer, L. B. Guze, 1979, The Journal of infectious diseases.

Paucity of V-D-D-J Rearrangements and VH Replacement Events in Lupus Prone and Nonautoimmune TdT−/− and TdT+/+ Mice1

A. Feeney, D. Nemazee, D. Kono, 2006, The Journal of Immunology.

Antibodies of predetermined specificity against chemically synthesized peptides of human interleukin 2.

R. Houghten, A. Altman, A. Theofilopoulos, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Elevated titers of cell-free interleukin 2 receptor in serum of lupus mice.

R. Balderas, A. Theofilopoulos, T. Diamantstein, 1987, Journal of immunology.

Lack of evidence for central T-cell tolerance defects in lupus mice and for V beta-deleting endogenous superantigens in rats and humans.

A. Theofilopoulos, R. Baccala, R. Gonzalez‐Quintial, 1992, Research in immunology.

Genetic diversity of murine rheumatoid factors.

R. Balderas, R. Kofler, A. Theofilopoulos, 1989, Journal of Immunology.

Inhibition of lupus by genetic alteration of the interferon-alpha/beta receptor.

D. Kono, A. Theofilopoulos, R. Baccala, 2003, Autoimmunity.

Complexity and sequence identification of 24 rat V beta genes.

L. Smith, D. Kono, A. Theofilopoulos, 1991, Journal of immunology.

Genes and genetics of autoimmunity

A. Theofilopoulos, 1999 .

Discovery of peptoid ligands for anti-aquaporin 4 antibodies.

T. Kodadek, J. Bennett, A. Theofilopoulos, 2013, Chemistry & biology.

Binding of components of the properdin system to cultured human lymphoblastoid cells and B lymphocytes

A. Theofilopoulos, L. Perrin, 1976, The Journal of experimental medicine.

V beta repertoire of murine hepatic T cells. Implication for selection of double negative alpha beta + T cells.

R. Balderas, D. Kono, A. Theofilopoulos, 1994, Journal of immunology.

Genetic studies in systemic autoimmunity and aging

D. Kono, A. Theofilopoulos, 2000, Immunologic research.

Circulating immune complexes in prosthetic valve endocarditis.

D. Hooper, A. Theofilopoulos, A. Bayer, 1983, Archives of internal medicine.

Staining and fluorescence-activated cell sorter analysis of human lymphocytes using antibodies to a short, chemically synthesized human IL-2 peptide.

A. Theofilopoulos, A. Altman, R. Fox, 1985, Cellular immunology.

Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger (Proceedings of the National Academy of Sciences of the United States of America (2008) 105, 39, (15028-15033) DOI: 10.1073/pnas.0806619105)

B. Beutler, A. Theofilopoulos, S. Pettersson, 2008 .

Recognition of human T-leukemia virus (HTLV-1) envelope by human CD4+ T-cell lines from HTLV-1 seronegative individuals: specificity and clonal heterogeneity.

R. Balderas, A. Dalgleish, A. Theofilopoulos, 1995, Blood.

Early modifications of host cell gene expression induced by HIV‐1

J. Corbeil, A. Theofilopoulos, D. Mosier, 1998, AIDS.

A genetic analysis of lupus

D. Kono, A. Theofilopoulos, A. Theofilopoulos, 2002, Allergy.

Independent of IL-4 Development of Lupus in BXSB Mice Is

D. Balomenos, D. Kono, A. Theofilopoulos, 1999 .

Genetics of Autoantibody Production in Mouse Models of Lupus

D. Kono, A. Theofilopoulos, 2006 .

C. Louis-dit-Sully, D. Kono, A. Theofilopoulos, 2008, Immunity.

Intracellular nucleic acid sensors and autoimmunity.

B. Beutler, D. Kono, A. Theofilopoulos, 2011, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Induction of murine autoimmune disease by chronic polyclonal B cell activation

A. Theofilopoulos, J. Slack, S. Izui, 1983, The Journal of experimental medicine.

Vβ gene repertoires in T cells expanded in local self‐healing and lethal systemic murine cutaneous leishmaniasis

R. Balderas, M. Lohoff, A. Theofilopoulos, 1994 .

Splenic immunoglobulin-secreting cells and their regulation in autoimmune mice

A. Theofilopoulos, Robert A. Eisenberg, Frank J. Dixon, 1980, The Journal of experimental medicine.

Establishment of an 'in vitro' Model of Dengue Infection for the Study of Immunologic Events in this Disease

A. Theofilopoulos, 1974 .

Critical role of transmethylation in TLR signaling and systemic lupus erythematosus.

Jian-Ping Zuo, D. Kono, A. Theofilopoulos, 2013, Clinical immunology.