Yuxiang Sun

发表

Ghrelin and Cancer: Examining the Roles of the Ghrelin Axis in Tumor Growth and Progression

Anuhya S. Kotta, Abigail S. Kelling, Karen A. Corleto, 2022, Biomolecules.

Ghrelin Is Produced in Taste Cells and Ghrelin Receptor Null Mice Show Reduced Taste Responsivity to Salty (NaCl) and Sour (Citric Acid) Tastants

M. Tschöp, J. Egan, Yuxiang Sun, 2010, PloS one.

Deletion of Ghrelin Impairs neither Growth nor Appetite

Yuxiang Sun, Roy G. Smith, Saira Ahmed, 2003, Molecular and Cellular Biology.

Ablation of ghrelin improves the diabetic but not obese phenotype of ob/ob mice.

P. Saha, Yuxiang Sun, Roy G. Smith, 2006, Cell metabolism.

Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice.

S. Geuna, Yuxiang Sun, M. Fornaro, 2013, The Journal of clinical investigation.

Dyrk2 mediated the release of proinflammatory cytokines in LPS-induced BV2 cells.

Yuxiang Sun, Li Xu, Mengmeng Li, 2017, International journal of biological macromolecules.

Reduced prealbumin is associated with bone mineral density in women with osteoporosis.

Yuxiang Sun, Ying Li, Tiemin Liu, 2017, Nutrition.

Shift work cycle‐induced alterations of circadian rhythms potentiate the effects of high‐fat diet on inflammation and metabolism

D. Earnest, R. Alaniz, Yuxiang Sun, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Central and Peripheral Roles of Ghrelin on Glucose Homeostasis

Yuxiang Sun, Roy G. Smith, M. Asnicar, 2007, Neuroendocrinology.

Molecular endocrinology and physiology of the aging central nervous system.

Yuxiang Sun, Roy G. Smith, L. Betancourt, 2005, Endocrine reviews.

Adenylate Kinase 4 Modulates the Resistance of Breast Cancer Cells to Tamoxifen through an m6A-Based Epitranscriptomic Mechanism.

Yuxiang Sun, Ming Huang, Ming Huang, 2020, Molecular therapy : the journal of the American Society of Gene Therapy.

Obestatin stimulates glucose-induced insulin secretion through ghrelin receptor GHS-R

S. Samson, Shaodong Guo, Yuxiang Sun, 2017, Scientific Reports.

The suppression of ghrelin signaling mitigates age-associated thermogenic impairment

Xiongwei Zhu, Xiaojun Ma, Yuxiang Sun, 2014, Aging.

Ablation of ghrelin receptor in leptin-deficient ob/ob mice has paradoxical effects on glucose homeostasis when compared with ablation of ghrelin in ob/ob mice.

N. Butte, G. Qin, Xiaojun Ma, 2012, American journal of physiology. Endocrinology and metabolism.

Spontaneous sleep and homeostatic sleep regulation in ghrelin knockout mice.

J. Krueger, Yuxiang Sun, Roy G. Smith, 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

Increased food intake leads to obesity and insulin resistance in the tg2576 Alzheimer's disease mouse model.

Yuxiang Sun, L. Chan, M. Kohjima, 2010, Endocrinology.

Unacylated Ghrelin Rapidly Modulates Lipogenic and Insulin Signaling Pathway Gene Expression in Metabolically Active Tissues of GHSR Deleted Mice

W. V. van IJcken, Yuxiang Sun, Roy G. Smith, 2010, PloS one.

A Novel Automated System Yields Reproducible Temporal Feeding Patterns in Laboratory Rodents

Yuxiang Sun, T. Wells, Jamie J. Walker, 2019, The Journal of nutrition.

L-Arginine Nutrition and Metabolism in Ruminants.

Guoyao Wu, Yuxiang Sun, F. Bazer, 2021, Advances in experimental medicine and biology.

Age-dependent remodeling of gut microbiome and host serum metabolome in mice

A. Jayaraman, Yuxiang Sun, S. Devaraj, 2021, Aging.

Coronal relay reactor Fe3O4@CeO2 for accelerating ROS axial conversion through enhanced Enzyme-like effect and relay effect

Yu Zhang, Yuxiang Sun, F. Xiong, 2022, Chemical Engineering Journal.

1,3,6,7‐Tetrahydroxy‐8‐prenylxanthone ameliorates inflammatory responses resulting from the paracrine interaction of adipocytes and macrophages

Xiuping Chen, Yuxiang Sun, Wen Sun, 2018, British journal of pharmacology.

GHS-R suppression in adipose tissues protects against obesity and insulin resistance by regulating adipose angiogenesis and fibrosis

Yuxiang Sun, R. Chapkin, K. Sun, 2021, International Journal of Obesity.

In vitro and in silico elucidation of antidiabetic and anti-inflammatory activities of bioactive compounds from Momordica charantia L.

B. Patil, G. Athrey, Yuxiang Sun, 2019, Bioorganic & medicinal chemistry.

Metabolic and inflammatory functions of cannabinoid receptor type 1 are differentially modulated by adiponectin

Shaodong Guo, Yuxiang Sun, Hui-Chen Lu, 2021, World journal of diabetes.

GHS-R in brown fat potentiates differential thermogenic responses under metabolic and thermal stresses

Shaodong Guo, Yuxiang Sun, C. Wolfrum, 2021, PloS one.

Adiponectin is required for maintaining normal body temperature in a cold environment

Zi-lin Sun, M. Bajaj, Yuxiang Sun, 2017, BMC Physiology.

Abnormal response to the anorexic effect of GHS-R inhibitors and exenatide in male Snord116 deletion mouse model for Prader-Willi syndrome.

Yuxiang Sun, Juan Wang, F. Ding, 2014, Endocrinology.

Effect of ghrelin on glucose regulation in mice.

J. Marini, P. Sauer, Xiaojun Ma, 2012, American journal of physiology. Endocrinology and metabolism.

Beclin-1-Dependent Autophagy Protects the Heart During Sepsis

J. Minei, B. Rothermel, Joseph A. Hill, 2018, Circulation.

Bis-Indole–Derived NR4A1 Ligands and Metformin Exhibit NR4A1-Dependent Glucose Metabolism and Uptake in C2C12 Cells

S. Safe, Jehoon Lee, Yuxiang Sun, 2018, Endocrinology.

Ghrelin receptor regulates appetite and satiety during aging in mice by regulating meal frequency and portion size but not total food intake.

F. Liu, Xiaojun Ma, Yuxiang Sun, 2014, The Journal of nutrition.

Protective effects of ghrelin on fasting-induced muscle atrophy in aging mice.

Guoyao Wu, S. Safe, J. Lawler, 2018, The journals of gerontology. Series A, Biological sciences and medical sciences.

Ghrelin receptor regulates adipose tissue inflammation in aging

C. Smith, Yuxiang Sun, E. Buras, 2016, Aging.

Ghrelin and growth hormone secretagogue receptor expression in mice during aging.

Yuxiang Sun, Roy G. Smith, Jose M Garcia, 2007, Endocrinology.

Developments in ghrelin biology and potential clinical relevance

Yuxiang Sun, Roy G. Smith, Hong Jiang, 2005, Trends in Endocrinology & Metabolism.

Role of the Growth Hormone Secretagogue Receptor in the Central Nervous System

Yuxiang Sun, R. Smith, L. Betancourt, 2002 .

Calorie restriction activates new adult born olfactory‐bulb neurones in a ghrelin‐dependent manner but acyl‐ghrelin does not enhance subventricular zone neurogenesis

Brianne A. Kent, L. Saksida, T. Bussey, 2019, Journal of neuroendocrinology.

Estrogen Improves Insulin Sensitivity and Suppresses Gluconeogenesis via the Transcription Factor Foxo1

Zheng Shen, Shaodong Guo, Yuxiang Sun, 2018, Diabetes.

Characterization of adult ghrelin and ghrelin receptor knockout mice under positive and negative energy balance.

N. Butte, Yuxiang Sun, Roy G. Smith, 2008, Endocrinology.

Severe Nephrotoxic Nephritis following Conditional and Kidney-Specific Knockdown of Stanniocalcin-1

L. Truong, Y. Lou, Yuxiang Sun, 2015, PloS one.

Ablation of Ghrelin Receptor Mitigates the Metabolic Decline of Aging Skeletal Muscle

J. Fluckey, Yuxiang Sun, Ligen Lin, 2022, Genes.

Deficient Ghrelin Receptor-mediated Signaling Compromises Thymic Stromal Cell Microenvironment by Accelerating Thymic Adiposity*

N. Manley, Yuxiang Sun, Roy G. Smith, 2009, Journal of Biological Chemistry.

The expression and function of growth hormone secretagogue receptor in immune cells: A current perspective

B. Patil, Yuxiang Sun, G. Wright, 2022, Experimental biology and medicine.

Restricted feeding-induced sleep, activity, and body temperature changes in normal and preproghrelin-deficient mice.

J. Krueger, Yuxiang Sun, Roy G. Smith, 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

Binding Domain Characterization of Growth Hormone Secretagogue Receptor

Yuxiang Sun, Roy G. Smith, X. Ye, 2022, Journal of translational internal medicine.

Neuronal GHS-R Differentially Modulates Feeding Patterns under Normal and Obesogenic Conditions

B. Xue, Yuxiang Sun, Zheng Chen, 2022, Biomolecules.

Ghrelin Receptors Enhance Fat Taste Responsiveness in Female Mice

Yuxiang Sun, T. Gilbertson, Tian Yu, 2021, Nutrients.

Ghrelin: Central Actions and Potential Implications in Neurodegenerative Diseases

Yuxiang Sun, Roy G. Smith, A. Paschali, 2004 .

Axin expression in thymic stromal cells contributes to an age‐related increase in thymic adiposity and is associated with reduced thymopoiesis independently of ghrelin signaling

C. Galbán, Yuxiang Sun, Hyunwon Yang, 2009, Journal of leukocyte biology.

An age-dependent interaction with leptin unmasks ghrelin's bone-protective effects.

Yuxiang Sun, Roy G. Smith, A. J. van der Lely, 2012, Endocrinology.

Reduction in hypophyseal growth hormone and prolactin expression due to deficiency in ghrelin receptor signaling is associated with Pit-1 suppression: Relevance to the immune system

D. Taub, Yuxiang Sun, Roy G. Smith, 2008, Brain, Behavior, and Immunity.

β Cell GHS-R Regulates Insulin Secretion and Sensitivity

A. Gaharwar, Shaodong Guo, Yuxiang Sun, 2021, International journal of molecular sciences.

Deletion of Growth Hormone Secretagogue Receptor in Kisspeptin Neurons in Female Mice Blocks Diet-Induced Obesity

Yuxiang Sun, T. Roepke, A. Yasrebi, 2022, Biomolecules.

Heme Oxygenase-1 Regulates Ferrous Iron and Foxo1 in Control of Hepatic Gluconeogenesis

Zheng Shen, Shaodong Guo, Yuxiang Sun, 2021, Diabetes.

Mitochondrial transcription factor A regulated ionizing radiation-induced mitochondrial biogenesis in human lung adenocarcinoma A549 cells

Yuxiang Sun, A. Xu, Hang Yuan, 2013, Journal of radiation research.

Megalin mediates plasma membrane to mitochondria cross-talk and regulates mitochondrial metabolism

Yi Tang, Q. Tong, Yuxiang Sun, 2018, Cellular and Molecular Life Sciences.

Microbiota-Mediated Immune Regulation in Atherosclerosis

A. Jayaraman, R. Alaniz, Yuxiang Sun, 2021, Molecules.

GHSR1a deficiency suppresses inhibitory drive on dCA1 pyramidal neurons and contributes to memory reinforcement.

Liu Yang, N. Li, Yuxiang Sun, 2022, Cerebral cortex.

Cucurbitane-type compounds from Momordica charantia: Isolation, in vitro antidiabetic, anti-inflammatory activities and in silico modeling approaches.

B. Patil, G. Athrey, Yuxiang Sun, 2019, Bioorganic chemistry.

Macrophage Polarization in Atherosclerosis

A. Jayaraman, R. Alaniz, Yuxiang Sun, 2022, Genes.

Diverse and Complementary Effects of Ghrelin and Obestatin

B. Xue, Yuxiang Sun, G. Pradhan, 2022, Biomolecules.

miR-593-3p Promotes Proliferation and Invasion in Prostate Cancer Cells by Targeting ADIPOR1

Yuxiang Sun, Hui Peng, Long Peng, 2021, OncoTargets and therapy.

Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor.

Hui Zheng, Yuxiang Sun, Roy G. Smith, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Gallotannin derivatives from mango ( Mangifera indica L.) suppress adipogenesis and increase thermogenesis in 3T3-L1 adipocytes in part through the AMPK pathway

Yuxiang Sun, S. Mertens-Talcott, G. Noratto, 2018, Journal of Functional Foods.

Adipocyte-Specific Ablation of PU.1 Promotes Energy Expenditure and Ameliorates Metabolic Syndrome in Aging Mice

N. McKenna, S. Ochsner, Q. Tong, 2021, bioRxiv.

The acidic transformed nano-VO2 causes macrophage cell death by the induction of lysosomal membrane permeabilization and Ca2+ efflux

Yuxiang Sun, A. Xu, Shengmin Xu, 2015, Toxicology reports.

Growth hormone secretagogues: prospects and potential pitfalls.

Yuxiang Sun, Roy G. Smith, M. Asnicar, 2004, Best practice & research. Clinical endocrinology & metabolism.

Ghrelin promotes thymopoiesis during aging.

A. Weeraratna, D. Taub, Yuxiang Sun, 2007, The Journal of clinical investigation.

Novel Role of Ghrelin Receptor in Gut Dysbiosis and Experimental Colitis in Aging

A. Jayaraman, R. Alaniz, Yuxiang Sun, 2022, International journal of molecular sciences.

Graphene oxide regulates cox2 in human embryonic kidney 293T cells via epigenetic mechanisms: dynamic chromosomal interactions

Yuxiang Sun, A. Xu, Sijin Liu, 2018, Nanotoxicology.

Histone Carbonylation Is a Redox-Regulated Epigenomic Mark That Accumulates with Obesity and Aging

M. O’Connor, D. Bernlohr, Yuxiang Sun, 2020, Antioxidants.

Nobiletin fortifies mitochondrial respiration in skeletal muscle to promote healthy aging against metabolic challenge

J. Takahashi, K. Esser, A. D’Alessandro, 2019, Nature Communications.

Growth Hormone Corrects Proliferation and Transcription of Phosphoenolpyruvate Carboxykinase in Livers of Old Mice via Elimination of CCAAT/Enhancer-binding Protein α-Brm Complex*

J. Albrecht, Yuxiang Sun, Roy G. Smith, 2007, Journal of Biological Chemistry.

Decoding the transcriptome of denervated muscle at single‐nucleus resolution

Zhaoyong Hu, Yuxiang Sun, Yanlin Wang, 2021, bioRxiv.

A Comprehensive High-Efficiency Protocol for Isolation, Culture, Polarization, and Glycolytic Characterization of Bone Marrow-Derived Macrophages.

A. Jayaraman, R. Alaniz, Yuxiang Sun, 2021, Journal of visualized experiments : JoVE.

Ablation of ghrelin receptor reduces adiposity and improves insulin sensitivity during aging by regulating fat metabolism in white and brown adipose tissues

P. Saha, O. McGuinness, Q. Tong, 2011, Aging cell.

GHS-R1a Deficiency Alleviates Depression-Related Behaviors After Chronic Social Defeat Stress

Yuxiang Sun, Jie Yang, Zhishang Zhou, 2019, Front. Neurosci..

Metformin Targets Foxo1 to Control Glucose Homeostasis

Shaodong Guo, Yuxiang Sun, Hongting Zheng, 2021, Biomolecules.

Ablations of Ghrelin and Ghrelin Receptor Exhibit Differential Metabolic Phenotypes and Thermogenic Capacity during Aging

G. Qin, Xiaojun Ma, Yuxiang Sun, 2011, PloS one.

Ghrelin Signaling in Immunometabolism and Inflamm-Aging.

Shaodong Guo, Yuxiang Sun, S. Mertens-Talcott, 2018, Advances in experimental medicine and biology.

New Insights on Neuronal Functions of Ghrelin Receptor GHS-R in Obesity

R. Alaniz, Yuxiang Sun, J. H. Lee, 2018, Journal of Neurology & Neuromedicine.

Bone mineral density is associated with left ventricular diastolic function in women

Yuxiang Sun, Tiemin Liu, Kai-Jiang Yu, 2016, Clinical cardiology.

Suppression of Ghrelin Exacerbates HFCS-Induced Adiposity and Insulin Resistance

Xiaojun Ma, Yuxiang Sun, S. Devaraj, 2017, International journal of molecular sciences.

Ghrelin: much more than a hunger hormone

S. Samson, Yuxiang Sun, G. Pradhan, 2013, Current opinion in clinical nutrition and metabolic care.

Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor.

A. Yamanaka, T. Sakurai, K. Toshinai, 2006, Endocrinology.

Effects of DTX3L on the cell proliferation, adhesion, and drug resistance of multiple myeloma cells

Yuxiang Sun, Hong Liu, Yaodong Shen, 2017, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.

Obestatin stimulates glucose-induced insulin secretion through ghrelin receptor GHS-R

S. Samson, Shaodong Guo, Yuxiang Sun, 2017, Scientific Reports.

Glucagon regulates hepatic mitochondrial function and biogenesis through FOXO1.

Shaodong Guo, Yuxiang Sun, Chaodong Wu, 2019, The Journal of endocrinology.

Anti-Inflammatory, Antidiabetic Properties and In Silico Modeling of Cucurbitane-Type Triterpene Glycosides from Fruits of an Indian Cultivar of Momordica charantia L.

Yuxiang Sun, J. Pérez, Wilmer H. Perera, 2021, Molecules.

Ghrelin receptor in agouti‐related peptide neurones regulates metabolic adaptation to calorie restriction

B. Xue, Yuxiang Sun, De-Pei Li, 2019, Journal of neuroendocrinology.

Ghrelin increases food intake and body weight by stimulating orexigenic agouti-related protein (AgRP)/neuropeptide Y (NPY) neurons and inhibiting anorexic pro-opiomelanocortin (POMC) neurons in the hypothalamus. Growth hormone secretagogue receptor (Ghsr) mediates the effect of ghrelin

Yuxiang Sun, De-Pei Li, H. Pan, 2017 .

Graphene oxide antagonizes the toxic response to arsenic via activation of protective autophagy and suppression of the arsenic-binding protein LEC-1 in Caenorhabditis elegans

Yuxiang Sun, A. Xu, A. Xu, 2018 .

Genetic manipulation of the ghrelin signaling system in male mice reveals bone compartment specificity of acylated and unacylated ghrelin in the regulation of bone remodeling.

Yuxiang Sun, Roy G. Smith, A. J. van der Lely, 2014, Endocrinology.

Postprandial inhibition of gastric ghrelin secretion by long-chain fatty acid through GPR120 in isolated gastric ghrelin cells and mice.

Yuxiang Sun, S. Pechhold, S. Wank, 2012, American journal of physiology. Gastrointestinal and liver physiology.

The preproghrelin gene is required for the normal integration of thermoregulation and sleep in mice

J. Krueger, Yuxiang Sun, Roy G. Smith, 2009, Proceedings of the National Academy of Sciences.

Novel Mechanism of Foxo1 Phosphorylation in Glucagon Signaling in Control of Glucose Homeostasis

F. Wondisford, Zihui Xu, Yunmei Chen, 2018, Diabetes.

Phosphorylation of Forkhead Protein FoxO1 at S253 Regulates Glucose Homeostasis in Mice.

D. Threadgill, M. White, Zihui Xu, 2019, Endocrinology.

Adipocyte expression of PU.1 transcription factor causes insulin resistance through upregulation of inflammatory cytokine gene expression and ROS production.

Q. Tong, Yuxiang Sun, W. Pang, 2012, American journal of physiology. Endocrinology and metabolism.

aP2-Cre Mediated Ablation of GHS-R Attenuates Adiposity and Improves Insulin Sensitivity during Aging

Yuxiang Sun, D. Sheikh-Hamad, Ligen Lin, 2018, International journal of molecular sciences.

Suppression of GHS-R in AgRP Neurons Mitigates Diet-Induced Obesity by Activating Thermogenesis

Shaodong Guo, Yuxiang Sun, De-Pei Li, 2017, International journal of molecular sciences.

Neuronal Deletion of Ghrelin Receptor Almost Completely Prevents Diet-Induced Obesity

Hui Zheng, Yuxiang Sun, Yong Xu, 2016, Diabetes.

Thermogenic characterization of ghrelin receptor null mice.

Yuxiang Sun, Ligen Lin, 2012, Methods in enzymology.

Mechanistic Investigation of GHS-R Mediated Glucose-Stimulated Insulin Secretion in Pancreatic Islets

B. Graham, S. Samson, Shaodong Guo, 2022, Biomolecules.

Thrifty Hormone Ghrelin: The Secret of Aging Muscularly

Yuxiang Sun, 2020, Journal of aging science.

Physiological roles revealed by ghrelin and ghrelin receptor deficient mice

Yuxiang Sun, Roy G. Smith, Rosie G. Albarran-Zeckler, 2011, Peptides.

Ghrelin is dispensable for embryonic pancreatic islet development and differentiation

Teresa L. Mastracci, L. Sussel, Yuxiang Sun, 2009, Regulatory Peptides.

Ghrelin Receptor (GHS‐R1A) Agonists Show Potential as Interventive Agents during Aging

Yuxiang Sun, Roy G. Smith, N. Timchenko, 2007, Annals of the New York Academy of Sciences.

A Cautionary Note for COVID-19 Survivors: Potential Long-term Risk for Alzheimer’s Disease

Yuxiang Sun, 2020, American journal of biomedical science & research.

Disruption of Chromosomal Architecture of cox2 Locus Sensitizes Lung Cancer Cells to Radiotherapy

Xianbin Cao, Yuxiang Sun, A. Xu, 2018, Molecular therapy : the journal of the American Society of Gene Therapy.

Acute But Not Chronic Calorie Restriction Defends against Stress-Related Anxiety and Despair in a GHS-R1a-Dependent Manner

Yuxiang Sun, Yingchang Lu, Zhishang Zhou, 2019, Neuroscience.

Mean platelet volume, platelet distribution width and carcinoembryonic antigen to discriminate gastric cancer from gastric ulcer

Yuxiang Sun, Tiemin Liu, Kai-Jiang Yu, 2017, Oncotarget.

Dyrk2 involved in regulating LPS-induced neuronal apoptosis.

Yuxiang Sun, Li Xu, Mengmeng Li, 2017, International journal of biological macromolecules.

A Simple High Efficiency Protocol for Pancreatic Islet Isolation from Mice.

Shaodong Guo, Yuxiang Sun, C. Allred, 2019, Journal of visualized experiments : JoVE.

through Up-regulation of Inflammatory Cytokine Gene Expression and ROS

Yuxiang Sun, W. Pang, Fei Wang, 2012 .

Ghrelin signaling in dCA1 suppresses neuronal excitability and impairs memory acquisition via PI3K/Akt/GSK-3β cascades

N. Li, Yuxiang Sun, Nan Li, 2021, Neuropharmacology.

Ghrelin receptor controls obesity by fat burning

Yuxiang Sun, 2015, Oncotarget.