V. Hong

发表

Identification and Kinetic Characterization of Serum- and Glucocorticoid-Regulated Kinase Inhibitors Using a Fluorescence Polarization–Based Assay

Jeongeun Kim, Donghee Kim, Hyunho Jung, 2021, SLAS discovery : advancing life sciences R & D.

KMU-1170, a Novel Multi-Protein Kinase Inhibitor, Suppresses Inflammatory Signal Transduction in THP-1 Cells and Human Osteoarthritic Fibroblast-Like Synoviocytes by Suppressing Activation of NF-κB and NLRP3 Inflammasome Signaling Pathway

Jinho Lee, V. Hong, Shin Kim, 2021, International journal of molecular sciences.

Synthesis and evaluation of 5-(3-(pyrazin-2-yl)benzylidene)thiazolidine-2,4-dione derivatives as pan-pim kinases inhibitors.

Jinho Lee, V. Hong, Jongseong Park, 2014, Chemical & pharmaceutical bulletin.

Pim kinase inhibitory and antiproliferative activity of a novel series of meridianin C derivatives.

Jinho Lee, V. Hong, H. Jang, 2014, Bioorganic & medicinal chemistry letters.

Structure-based design of low-nanomolar PIM kinase inhibitors.

L. Silvian, I. Enyedy, B. Elenbaas, 2015, Bioorganic & medicinal chemistry letters.

Anti-Inflammatory Effects of the Novel PIM Kinase Inhibitor KMU-470 in RAW 264.7 Cells through the TLR4-NF-κB-NLRP3 Pathway

T. Kwon, Jinho Lee, V. Hong, 2020, International journal of molecular sciences.

Inhibition of adipogenesis and leptin production in 3T3-L1 adipocytes by a derivative of meridianin C.

B. Jang, Jong-Wook Park, Jinho Lee, 2014, Biochemical and biophysical research communications.

AMIGO2, a novel membrane anchor of PDK1, controls cell survival and angiogenesis via Akt activation

S. Ha, Weontae Lee, N. Mochizuki, 2015, The Journal of cell biology.

Antioxidant activity of 3,4,5-trihydroxyphenylacetamide derivatives

Jinho Lee, V. Hong, Jina Kim, 2014, Archives of pharmacal research.

3,5-Bis(aminopyrimidinyl)indole Derivatives: Synthesis and Evaluation of Pim Kinase Inhibitory Activities

Jinho Lee, V. Hong, Seun-ah Yang, 2014 .

Meridianin C inhibits the growth of YD‐10B human tongue cancer cells through macropinocytosis and the down‐regulation of Dickkopf‐related protein‐3

M. Noguchi, J. Kano, I. Jang, 2018, Journal of cellular and molecular medicine.

The novel anti-adipogenic effect and mechanisms of action of SGI-1776, a Pim-specific inhibitor, in 3T3-L1 adipocytes.

B. Jang, Jinho Lee, V. Hong, 2016, International journal of molecular medicine.

Discovery of renin inhibitors containing a simple aspartate binding moiety that imparts reduced P450 inhibition.

D. Holt, S. Semus, Baochau Le, 2017, Bioorganic & medicinal chemistry letters.

EC144 is a potent inhibitor of the heat shock protein 90.

S. Kasibhatla, I. Enyedy, C. Ambrose, 2012, Journal of medicinal chemistry.

Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism.

Joachim Kraemer, Deping Wang, Dirk Winkler, 2013, Bioorganic & medicinal chemistry.

Differential Protein Expression During Tail Regeneration of Anolis carolinensis

V. Hong, Benjamin Thornton, B. Thornton, 2015 .

Oncogenic MST1R activity in pancreatic and gastric cancer represents a valid target of HSP90 inhibitors.

O. Stoeltzing, Hong Zhang, J. Park, 2012, Anticancer research.

Increased cathepsin D release by Hyp mouse osteoblast cells.

O. Jo, V. Hong, J. Yanagawa, 2005, American journal of physiology. Endocrinology and metabolism.

Identification of KMU-3, a Novel Derivative of Gallic Acid, as an Inhibitor of Adipogenesis

B. Jang, Jinho Lee, V. Hong, 2014, PloS one.

1,3, 4‐Oxadiazole ‐2( 3 H )‐thione Analogs as PIM Kinase Inhibitors

Jinho Lee, V. Hong, Yang Yun, 2020 .

Discovery and evaluation of 3,5-disubstituted indole derivatives as Pim kinase inhibitors.

Shin Kim, Jongsun Park, Jinho Lee, 2018, Bioorganic & medicinal chemistry letters.

Development and Application of a High-Throughput Fluorescence Polarization Assay to Target Pim Kinases.

V. Hong, S. Lee, 2016, Assay and drug development technologies.

Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases

L. Silvian, D. Baker, V. Hong, 2010, Protein science : a publication of the Protein Society.

Systems-based design of bi-ligand inhibitors of oxidoreductases: filling the chemical proteomic toolbox.

Maurizio Pellecchia, Daniel S Sem, H. Villar, 2004, Chemistry & biology.

Discovery of biaryl carboxylamides as potent RORγ inverse agonists.

N. Powell, L. Silvian, I. Enyedy, 2015, Bioorganic & medicinal chemistry letters.

Synthesis of (Z)-3-((1H-imidazol-5-yl)methylene)indolin-2-one Derivatives as Pim Kinase Inhibitors

Kang Ji Hee, V. Hong, Lee， Jinho, 2018 .

Chronic Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Activity Decreases Hypertension, Insulin Resistance, and Hypertriglyceridemia in Metabolic Syndrome

R. Willette, T. Yue, V. Hong, 2013, BioMed research international.

Discovery of biaryls as RORγ inverse agonists by using structure-based design.

Istvan J Enyedy, N. Powell, L. Silvian, 2016, Bioorganic & medicinal chemistry letters.

Synthesis and anti-proliferative activity evaluation of N3-acyl-N5-aryl-3,5-diaminoindazole analogues as anti-head and neck cancer agent

Jong-Wook Park, Jinho Lee, V. Hong, 2014, DARU Journal of Pharmaceutical Sciences.

Synthesis and anti-proliferative activity evaluation of N3-acyl-N5-aryl-3,5-diaminoindazole analogues as anti-head and neck cancer agent

Jinho Lee, V. Hong, Jina Kim, 2014, DARU Journal of Pharmaceutical Sciences.

Antioxidant activity of 3,4,5-trihydroxyphenylacetamide derivatives

Jinho Lee, V. Hong, Jin-Ah Kim, 2013, Archives of Pharmacal Research.

KMU-191 Induces Apoptosis in Human Clear Cell Renal Cell Carcinoma Caki Cells Through Modulation of Bcl-xL, Mcl-1 (L), c-FLIP (L), and p53 Proteins

Dong Eun Kim, Jong-Wook Park, Jinho Lee, 2023, Journal of Cancer.

The novel anti-adipogenic effect and mechanisms of action of SGI-1776, a Pim-specific inhibitor, in 3T3-L1 adipocytes.

B. Jang, Jinho Lee, V. Hong, 2016, International journal of molecular medicine.