J. Hoyland

J. Hoyland, P. Saunders, P. Selby, 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Studies of the microvascular endothelium in uninvolved skin of patients with systemic sclerosis: direct evidence for a generalized microangiopathy

M. Jayson, J. Hoyland, P. Fielding, 1992, The British journal of dermatology.

Down-regulation of human osteoblast PTH/PTHrP receptor mRNA in end-stage renal failure.

A. Freemont, D. Houghton, J. Hoyland, 2000, Kidney international.

Role of OSCAR Signaling in Osteoclastogenesis and Bone Disease

J. Bella, J. Hoyland, A. Elson, 2021, Frontiers in Cell and Developmental Biology.

Importance of Matrix Cues on Intervertebral Disc Development, Degeneration, and Regeneration

M. Domingos, S. Richardson, J. Hoyland, 2022, International journal of molecular sciences.

Gene expression of matrix metalloproteinases 1, 3, and 9 by chondrocytes in osteoarthritic human knee articular cartilage is zone and grade specific

A. Freemont, J. Hoyland, P. Goupille, 1997, Annals of the rheumatic diseases.

Osteoporosis in men: a cellular endocrine perspective of an increasingly common clinical problem.

J. Hoyland, R. Byers, I. Braidman, 2001, The Journal of endocrinology.

Preliminary report of impaired oestrogen receptor‐α expression in bone, but no involvement of androgen receptor, in male idiopathic osteoporosis

J. Adams, A. Freemont, J. Hoyland, 2000, The Journal of pathology.

Cellular mechanisms of renal osteodystrophy.

J. Hoyland, M. Picton, Michael L. Picton, 1999, Kidney international. Supplement.

Peptide location fingerprinting identifies species- and tissue-conserved structural remodelling of proteins as a consequence of ageing and disease.

H. Schiller, J. Hoyland, D. Chan, 2022, Matrix biology : journal of the International Society for Matrix Biology.

The effects of lanthanum carbonate and calcium carbonate on bone abnormalities in patients with end-stage renal disease.

A. Freemont, J. Hoyland, J. Denton, 2005, Clinical nephrology.

An optimized culture system for notochordal cell expansion with retention of phenotype

S. Richardson, J. Hoyland, Lizzy Ward, 2018, JOR spine.

Mast cells in the synovium and synovial fluid in osteoarthritis.

A. Freemont, J. Hoyland, J. Denton, 1993, British journal of rheumatology.

Novel immortal human cell lines reveal subpopulations in the nucleus pulposus

J. Voncken, S. Richardson, J. Hoyland, 2014, Arthritis Research & Therapy.

Altered integrin mechanotransduction in human nucleus pulposus cells derived from degenerated discs.

A. Freemont, C. L. Le Maitre, J. Hoyland, 2009, Arthritis and rheumatism.

Regenerative Response of Degenerate Human Nucleus Pulposus Cells to GDF6 Stimulation

S. Richardson, J. Hoyland, T. Hodgkinson, 2020, International journal of molecular sciences.

Human Adipose-Derived Stem Cells Exhibit Enhanced Proliferative Capacity and Retain Multipotency Longer than Donor-Matched Bone Marrow Mesenchymal Stem Cells during Expansion In Vitro

S. Richardson, J. Hoyland, K. Burrow, 2017, Stem cells international.

Exploiting the role of nanoparticle shape in enhancing hydrogel adhesive and mechanical properties

S. Richardson, J. Hoyland, A. Binch, 2020, Nature Communications.

Correction: Human decellularized bone scaffolds from aged donors show improved osteoinductive capacity compared to young donor bone

S. Richardson, J. Hoyland, T. Board, 2017, PloS one.

Human decellularized bone scaffolds from aged donors show improved osteoinductive capacity compared to young donor bone

S. Richardson, J. Hoyland, T. Board, 2017, PloS one.

Co-culture induces mesenchymal stem cell differentiation and modulation of the degenerate human nucleus pulposus cell phenotype.

A. Freemont, S. Richardson, J. Hoyland, 2010, Regenerative medicine.

Development of an in vitro model to test the efficacy of novel therapies for IVD degeneration

A. Freemont, C. L. Le Maitre, J. Hoyland, 2009, Journal of tissue engineering and regenerative medicine.

17 – Intervertebral disc tissue engineering

J. Hoyland, T. Freemont, 2007 .

Matrix synthesis and degradation in human intervertebral disc degeneration.

A. Freemont, C. L. Le Maitre, J. Hoyland, 2007, Biochemical Society transactions.

Increased expression of matrix metalloproteinase-10, nerve growth factor and substance P in the painful degenerate intervertebral disc

S. Richardson, J. Hoyland, B. Minogue, 2009, Arthritis research & therapy.

An understanding of intervertebral disc development, maturation and cell phenotype provides clues to direct cell-based tissue regeneration therapies for disc degeneration

S. Richardson, J. Hoyland, R. Rodrigues-Pinto, 2014, European Spine Journal.

Growth differentiation factor 6 and transforming growth factor-beta differentially mediate mesenchymal stem cell differentiation, composition, and micromechanical properties of nucleus pulposus constructs

B. Derby, S. Richardson, J. Hoyland, 2014, Arthritis Research & Therapy.

Routine expression profiling of microarray gene signatures in acute leukaemia by real‐time PCR of human bone marrow *

Gerard Brady, J. Hoyland, E. Sakhinia, 2005, British journal of haematology.

Gene expression analysis of myeloid and lymphoid lineage markers during mouse haematopoiesis

A. Bashein, J. Hoyland, E. Sakhinia, 2006, British journal of haematology.

Expression of the imprinted tumour‐suppressor gene H19 is tightly regulated during normal haematopoiesis and is reduced in haematopoietic precursors of patients with the myeloproliferative disease polycythaemia vera

A. Bashein, A. Freemont, J. Hoyland, 2000 .

Expression of the imprinted tumour-suppressor gene H19 is tightly regulated during normal haematopoiesis and is reduced in haematopoietic precursors of patients with the myeloproliferative disease polycythaemia vera.

A. Bashein, A. Freemont, J. Hoyland, 2000, The Journal of pathology.

Altered relative expression of BMPs and BMP inhibitors in cartilaginous areas of human fractures progressing towards nonunion

A. Freemont, J. Hoyland, Francois N. K. Kwong, 2009, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Integrin – Dependent Mechanotransduction in Mechanically Stimulated Human Annulus Fibrosus Cells: Evidence for an Alternative Mechanotransduction Pathway Operating with Degeneration

A. Freemont, J. Hoyland, N. Nagra, 2013, PloS one.

Spatiotemporal analysis of putative notochordal cell markers reveals CD24 and keratins 8, 18, and 19 as notochord‐specific markers during early human intervertebral disc development

N. Hanley, S. Richardson, J. Hoyland, 2016, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

The bcl‐2 knockout mouse exhibits marked changes in osteoblast phenotype and collagen deposition in bone as well as a mild growth plate phenotype

A. Freemont, R. Boot-Handford, J. Hoyland, 1998, International journal of experimental pathology.

Hydroxyapatite-decorated Fmoc-hydrogel as a bone-mimicking substrate for osteoclast differentiation and culture

Chris Allan, J. Bella, S. Richardson, 2021, Acta biomaterialia.

Preliminary evidence for impaired estrogen receptor-alpha protein expression in osteoblasts and osteocytes from men with idiopathic osteoporosis.

J. Adams, A. Freemont, J. Hoyland, 2000, Bone.

Apoptotic gene expression in Paget's disease: a possible role for Bcl‐2

J. Hoyland, J. Berry, P. Selby, 2003, The Journal of pathology.

Degenerate Human Nucleus Pulposus Cells Promote Neurite Outgrowth in Neural Cells

A. Freemont, S. Richardson, J. Hoyland, 2012, PloS one.

Immunofluorescent localization of estrogen receptor-alpha in growth plates of rabbits, but not in rats, at sexual maturity.

A. Freemont, J. Hoyland, P. Selby, 1999, Bone.

Trabecular Bone Formation in the Healing of the Rodent Molar Tooth Extraction Socket

S. Ayad, J. Hoyland, H. Devlin, 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Human cells derived from degenerate intervertebral discs respond differently to those derived from non-degenerate intervertebral discs following application of dynamic hydrostatic pressure.

A. Freemont, C. L. Le Maitre, J. Hoyland, 2008, Biorheology.

Facilitative glucose transporters in articular chondrocytes. Expression, distribution and functional regulation of GLUT isoforms by hypoxia, hypoxia mimetics, growth factors and pro-inflammatory cytokines.

A. F. Mendes, A. Mobasheri, M. Shakibaei, 2008, Advances in anatomy, embryology, and cell biology.

Demonstration of variation in chondrocyte activity in different zones of articular cartilage: an assessment of the value of in-situ hybridization.

A. Freemont, J. Hoyland, P. J. Marles, 1991, International journal of experimental pathology.

Simultaneous orthogonal dual-click approach to tough, in-situ-forming hydrogels for cell encapsulation.

V. Truong, S. Richardson, J. Hoyland, 2015, Journal of the American Chemical Society.

Mesenchymal stem cells in regenerative medicine: Opportunities and challenges for articular cartilage and intervertebral disc tissue engineering

A. Mobasheri, M. Shakibaei, S. Richardson, 2010, Journal of cellular physiology.

The human collagen X gene: complete primary sequence and re-expression in osteoarthritis.

J. T. Thomas, A. Freemont, R. Boot-Handford, 1991, Biochemical Society transactions.

The effect of tissue decalcification on mRNA retention within bone for in-situ hybridization studies.

A. Freemont, J. Hoyland, L. Walsh, 1993, International journal of experimental pathology.

The unique calcium chelation property of poly(vinyl phosphonic acid‐co‐acrylic acid) and effects on osteogenesis in vitro

S. Downes, P. Budd, D. Watts, 2017, Journal of biomedical materials research. Part A.

The incidence and significance of psammoma bodies within nerve roots of cadaveric lumbar spines

A. Freemont, J. Hoyland, 1991 .

Intervertebral Foramen Venous Obstruction: A Cause of Periradicular Fibrosis?

M. Jayson, A. Freemont, J. Hoyland, 1989, Spine.

Dual colour FISH in paraffin wax embedded bone trephines for identification of numerical and structural chromosomal abnormalities in acute myeloid leukaemia and myelodysplasia.

A. Freemont, J. Hoyland, J. A. Liu Yin, 2001, Journal of clinical pathology.

Highly compressive and stretchable poly(ethylene glycol) based hydrogels synthesised using pH-responsive nanogels without free-radical chemistry.

A. Freemont, J. Hoyland, B. Saunders, 2019, Nanoscale.

Injectable biocompatible and biodegradable pH-responsive hollow particle gels containing poly(acrylic acid): the effect of copolymer composition on gel properties.

J. Hoyland, B. Saunders, Eseelle K. Hendow, 2014, Biomacromolecules.

Programmed Multiresponsive Hydrogel Assemblies with Light‐Tunable Mechanical Properties, Actuation, and Fluorescence

Shangli Wu, J. Hoyland, B. Saunders, 2020, Advanced Functional Materials.

A comparison of in situ hybridisation, reverse transcriptase-polymerase chain reaction (RT-PCR) and in situ-RT-PCR for the detection of canine distemper virus RNA in Paget's disease.

J. Hoyland, J. Berry, P. Selby, 2003, Journal of virological methods.

Thermally-triggered gelation of PLGA dispersions: towards an injectable colloidal cell delivery system.

K. Shakesheff, A. Freemont, S. Richardson, 2010, Journal of colloid and interface science.

A study of physical and covalent hydrogels containing pH-responsive microgel particles and graphene oxide.

A. Freemont, J. Hoyland, I. Kinloch, 2014, Langmuir : the ACS journal of surfaces and colloids.

In situ-forming robust chitosan-poly(ethylene glycol) hydrogels prepared by copper-free azide-alkyne click reaction for tissue engineering.

V. Truong, S. Richardson, J. Hoyland, 2014, Biomaterials science.

Use of lecithin to control fiber morphology in electrospun poly (ɛ‐caprolactone) scaffolds for improved tissue engineering applications

J. Hoyland, J. Gough, W. Sampson, 2017, Journal of biomedical materials research. Part A.

Facilitative Glucose Transporters in Articular Chondrocytes

A. F. Mendes, A. Mobasheri, M. Shakibaei, 2008 .

The role of interleukin-1 in the pathogenesis of human Intervertebral disc degeneration

A. Freemont, C. L. Le Maitre, J. Hoyland, 2005, Arthritis research & therapy.

LIST OF ABBREVIATIONS AF : Annulus Fibrosus ADAMTS : A Disintegrin And Metalloproteinase with Thrombospondin Motifs

D. Kletsas, M. Risbud, J. Hoyland, 2016 .

Responsive Nanogel Probe for Ratiometric Fluorescent Sensing of pH and Strain in Hydrogels.

A. Freemont, Shangli Wu, J. Hoyland, 2017, ACS macro letters.

Exploiting the role of nanoparticle shape in enhancing hydrogel adhesive and mechanical properties

S. Richardson, J. Hoyland, A. Binch, 2020, Nature Communications.

A microstereolithography resin based on thiol-ene chemistry: towards biocompatible 3D extracellular constructs for tissue engineering.

J. Covington, S. Leigh, S. Richardson, 2014, Biomaterials science.

Expression of cartilage-derived morphogenetic protein in human intervertebral discs and its effect on matrix synthesis in degenerate human nucleus pulposus cells

A. Freemont, C. L. Le Maitre, J. Hoyland, 2009, Arthritis research & therapy.

Human notochordal cell transcriptome unveils potential regulators of cell function in the developing intervertebral disc

N. Hanley, S. Richardson, J. Hoyland, 2018, Scientific Reports.

Notochordal and nucleus pulposus marker expression is maintained by sub-populations of adult human nucleus pulposus cells through aging and degeneration

A. Freemont, S. Richardson, J. Hoyland, 2017, Scientific Reports.

Understanding the native nucleus pulposus cell phenotype has important implications for intervertebral disc regeneration strategies.

S. Richardson, J. Hoyland, K. Gnanalingham, 2013, Regenerative medicine.

Characterization of the human nucleus pulposus cell phenotype and evaluation of novel marker gene expression to define adult stem cell differentiation.

A. Freemont, S. Richardson, J. Hoyland, 2010, Arthritis and rheumatism.

The response of human anulus fibrosus cells to cyclic tensile strain is frequency-dependent and altered with disc degeneration.

J. Hoyland, S. J. Millward-Sadler, Hamish T. J. Gilbert, 2010, Arthritis and rheumatism.

Expression of chondrocyte markers by cells of normal and degenerate intervertebral discs

A. Freemont, J. Hoyland, P. Baird, 2002, Molecular pathology : MP.

Therapeutic potential of growth differentiation factors in the treatment of degenerative disc diseases

S. Richardson, J. Hoyland, T. Hodgkinson, 2019, JOR spine.

Self-Assembling Peptide Hydrogels as Functional Tools to Tackle Intervertebral Disc Degeneration

J. Hoyland, A. Saiani, C. Ligorio, 2022, Gels.

Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degeneration

A. Freemont, J. Hoyland, Judith A Hoyland, 2009, Arthritis research & therapy.

A preliminary in vitro study into the use of IL‐1Ra gene therapy for the inhibition of intervertebral disc degeneration

A. Freemont, C. L. Le Maitre, J. Hoyland, 2006, International journal of experimental pathology.

Expression of receptors for putative anabolic growth factors in human intervertebral disc: implications for repair and regeneration of the disc

A. Freemont, C. L. Le Maitre, S. Richardson, 2005, The Journal of pathology.

Upregulation of c‐Fos protooncogene expression in pagetic osteoclasts

J. Hoyland, P. Sharpe, 1994, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Quantitative multiplex quantum dot in-situ hybridisation based gene expression profiling in tissue microarrays identifies prognostic genes in acute myeloid leukaemia.

E. Tholouli, J. Hoyland, R. Byers, 2012, Biochemical and biophysical research communications.

Cell adhesion molecules

A. Freemont, J. Hoyland, A. Freemont, 1996, Clinical molecular pathology.

Detection of canine distemper virus in 100% of Paget's disease samples by in situ-reverse transcriptase-polymerase chain reaction.

J. Hoyland, P. Selby, E. Mawer, 1998, Bone.

Canine bone marrow cell cultures infected with canine distemper virus: an in vitro model of Paget's disease.

J. Hoyland, P. Sharpe, P. Baird, 1995, Bone.

Interleukin‐6, IL‐6 receptor, and IL‐6 nuclear factor gene expression in paget's disease

A. Freemont, J. Hoyland, P. Sharpe, 1994, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The expression of types X and VI collagen and fibrillin in rat mandibular condylar cartilage. Response to mastication forces.

J. T. Thomas, A. Freemont, S. Ayad, 1996, Acta odontologica Scandinavica.

Peptide location fingerprinting identifies species- and tissue-conserved structural remodelling of proteins as a consequence of ageing and disease

H. Schiller, J. Hoyland, D. Chan, 2022, bioRxiv.

Nonviral Transfection With Brachyury Reprograms Human Intervertebral Disc Cells to a Pro‐Anabolic Anti‐Catabolic/Inflammatory Phenotype: A Proof of Concept Study

Safdar N. Khan, D. Gallego-Perez, J. Hoyland, 2019, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Adipocytic proportion of bone marrow is inversely related to bone formation in osteoporosis

J Denton, J. Hoyland, J. Denton, 2002, Journal of clinical pathology.

TGF-β3-Loaded Graphene Oxide - Self-Assembling Peptide Hybrid Hydrogels as Functional 3D Scaffolds for the Regeneration of the Nucleus Pulposus

A. Miller, A. Vijayaraghavan, J. Hoyland, 2021, Acta biomaterialia.

Intervertebral Disc Cell–Mediated Mesenchymal Stem Cell Differentiation

A. Freemont, S. Richardson, J. Hoyland, 2006, Stem cells.

The Distribution of Type VI Collagen in the Developing Tissues of the Bovine Femoral Head

S. Ayad, J. Hoyland, A. Sherwin, 1999, The Histochemical Journal.

Circadian time series proteomics reveals daily dynamics in cartilage physiology

K. Kadler, J. Hoyland, C. Lawless, 2019, bioRxiv.

Lineage plasticity and cell biology of fibrocartilage and hyaline cartilage: its significance in cartilage repair and replacement.

A. Freemont, J. Hoyland, 2006, European journal of radiology.

An in vitro study investigating the survival and phenotype of mesenchymal stem cells following injection into nucleus pulposus tissue

A. Freemont, C. L. Le Maitre, J. Hoyland, 2009, Arthritis research & therapy.

PolyA PCR Amplification of cDNA from RNA Extracted from Formalin-Fixed Paraffin-Embedded Tissue

J. Hoyland, E. Sakhinia, R. Byers, 2004, Diagnostic molecular pathology : the American journal of surgical pathology, part B.

Histomorphometric classification of postmenopausal osteoporosis: implications for the management of osteoporosis.

A. Freemont, J. Hoyland, J. Denton, 1995, Journal of clinical pathology.

Harmonization and standardization of nucleus pulposus cell extraction and culture methods

L. Setton, P. Kraus, T. Lufkin, 2023, JOR spine.

Subtractive hybridization – genetic takeaways and the search for meaning

A. Freemont, J. Hoyland, R. Byers, 2000, International journal of experimental pathology.

Peptide Location Fingerprinting Reveals Tissue Region-Specific Differences in Protein Structures in an Ageing Human Organ

J. Hoyland, A. Trafford, M. Sherratt, 2021, International journal of molecular sciences.

YY1 expression predicts favourable outcome in follicular lymphoma

J. Radford, T. Illidge, J. Hoyland, 2010, Journal of Clinical Pathology.

Localization of pro-collagen type II mRNA and collagen type II in the healing tooth socket of the rat.

A. Freemont, J. Hoyland, P. Sloan, 1995, Archives of oral biology.

Regional variations in discrete collagen fibre mechanics within intact intervertebral disc resolved using synchrotron computed tomography and digital volume correlation

B. Bay, A. Pitsillides, A. Bodey, 2021, Acta biomaterialia.

In situ Tracking of Individual Collagen Fibre Bundles in Intact Loaded Intervertebral Discs Exposes Damage-Susceptible Collagen Organisations

B. Bay, A. Pitsillides, A. Bodey, 2021, SSRN Electronic Journal.

Clinical quantitation of diagnostic and predictive gene expression levels in follicular and diffuse large B-cell lymphoma by RT-PCR gene expression profiling.

Crispin Miller, Gerard Brady, Crispin J. Miller, 2007, Blood.

Clinical quantitation of immune signature in follicular lymphoma by RT-PCR-based gene expression profiling.

J. Radford, T. Illidge, J. Hoyland, 2008, Blood.

Demonstration of TGF-β1 mRNA by in situ hybridization in normal human fracture healing

A. Freemont, D. Marsh, J. Hoyland, 1993, Calcified Tissue International.

A. Freemont, J. Hoyland, J. Denton, 1994, Journal of clinical pathology.

From multipotent cells to fully differentiated connective tissue cells for regenerative medicine: emerging applications of mesenchymal stem cells

A. Mobasheri, M. Shakibaei, S. Richardson, 2011 .

Herniated Intervertebral Disc-Associated Periradicular Fibrosis and Vascular Abnormalities Occur Without Inflammatory Cell Infiltration

M. Jayson, R. Cooper, J. Hoyland, 1995, Spine.

Retained surgical swab debris in post-laminectomy arachnoiditis and peridural fibrosis.

M. Jayson, A. Freemont, J. Hoyland, 1988, The Journal of bone and joint surgery. British volume.

RT-PCR based gene expression profiling Clinical quantitation of immune signature in follicular lymphoma by

J. Radford, T. Illidge, J. Hoyland, 2013 .

profiling follicular and diffuse large B-cell lymphoma by RT-PCR gene expression Clinical quantitation of diagnostic and predictive gene expression levels in

Crispin J. Miller, J. Hoyland, E. Sakhinia, 2013 .

Imaging of multiple mRNA targets using quantum dot based in situ hybridization and spectral deconvolution in clinical biopsies.

David Twomey, Todd R Golub, Richard Levenson, 2006, Biochemical and biophysical research communications.

Human mesenchymal stem cell differentiation to NP-like cells in chitosan-glycerophosphate hydrogels.

A. Freemont, S. Richardson, J. Hoyland, 2008, Biomaterials.

Do the properties of gels constructed by interlinking triply-responsive microgels follow from those of the building blocks?

K. Landfester, Shangli Wu, J. Hoyland, 2019, Soft matter.

A study of conductive hydrogel composites of pH-responsive microgels and carbon nanotubes.

J. Hoyland, I. Kinloch, B. Saunders, 2016, Soft matter.

The involvement of interleukin-1 and interleukin-4 in the response of human annulus fibrosus cells to cyclic tensile strain: an altered mechanotransduction pathway with degeneration

A. Freemont, J. Hoyland, S. J. Millward-Sadler, 2011, Arthritis Research & Therapy.

Mechanical loading and hyperosmolarity as a daily resetting cue for skeletal circadian clocks

F. Guilak, J. Hoyland, Zhuojing Luo, 2021, bioRxiv.

Acidic pH promotes intervertebral disc degeneration: Acid-sensing ion channel -3 as a potential therapeutic target

S. Richardson, J. Hoyland, N. Hodson, 2016, Scientific Reports.

Critical aspects and challenges for intervertebral disc repair and regeneration—Harnessing advances in tissue engineering

J. Iatridis, J. Hoyland, S. Grad, 2018, JOR spine.

Acidic and Basic Self-Assembling Peptide and Peptide-Graphene Oxide Hydrogels: Characterisation and Effect on Encapsulated Nucleus Pulposus Cells.

A. Vijayaraghavan, J. Hoyland, A. Saiani, 2022, Acta biomaterialia.

TGF-β3-Loaded Graphene Oxide - Self-Assembling Peptide Hybrid Hydrogels as Functional 3D Scaffolds for the Regeneration of the Nucleus Pulposus

A. Miller, A. Vijayaraghavan, J. Hoyland, 2021 .

Graphene oxide containing self-assembling peptide hybrid hydrogels as a potential 3D injectable cell delivery platform for intervertebral disc repair applications

A. Miller, A. Vijayaraghavan, J. Hoyland, 2019, Acta biomaterialia.

Designing Peptide/Graphene Hybrid Hydrogels through Fine-Tuning of Molecular Interactions.

A. Miller, A. Vijayaraghavan, J. Hoyland, 2018, Biomacromolecules.

Hydrogel Composites Containing Sacrificial Collapsed Hollow Particles as Dual Action pH-Responsive Biomaterials.

Kyriaki S. Pafiti, A. Freemont, J. Hoyland, 2016, Biomacromolecules.

The clock transcription factor BMAL1 is a key regulator of extracellular matrix homeostasis and cell fate in the intervertebral disc

K. Kadler, J. Hoyland, D. Chan, 2023, bioRxiv.

Tissue physiology revolving around the clock: circadian rhythms as exemplified by the intervertebral disc

J. Hoyland, Q. Meng, M. Dudek, 2021, Annals of the Rheumatic Diseases.

Growth differentiation factor 6 promotes a healthy nucleus pulposus cell phenotype through smad and smad-independent signalling pathways

S. Richardson, J. Hoyland, T. Hodgkinson, 2018 .

Tissue section AFM: In situ ultrastructural imaging of native biomolecules

Thomas R. Cox, Andrew W. Trafford, J. Erler, 2010, Matrix biology : journal of the International Society for Matrix Biology.

Synchrotron Tomographic Measurement of Strain in Soft Tissue: Native Intervertebral Disc Deformation at Histological Resolution

B. Bay, A. Bodey, J. Hoyland, 2019, SSRN Electronic Journal.

Effect of ovarian steroid deficiency on oestrogen receptor α expression in bone

A. Freemont, J. Hoyland, P. Selby, 1999, The Journal of pathology.

Injectable Colloidal Hydrogels of N-Vinylformamide Microgels Dispersed in Covalently Interlinked pH-Responsive Methacrylic Acid-Based Microgels

J. Hoyland, B. Saunders, Zhenyu Jia, 2023, Biomacromolecules.

In situ hybridization and in situ reverse transcription polymerase chain reaction in human bone sections.

J. Hoyland, A. Mee, 2003, Methods in molecular medicine.

QUANTIFICATION OF VITAMIN D RECEPTOR mRNA IN TISSUE SECTIONS DEMONSTRATES THE RELATIVE LIMITATIONS OF IN SITU‐REVERSE TRANSCRIPTASE‐POLYMERASE CHAIN REACTION

J. Hoyland, E. Mawer, J. Denton, 1997, The Journal of pathology.

New histological observations in spontaneously developing osteoarthritis in the STR/ORT mouse questioning its acceptability as a model of human osteoarthritis.

A. Freemont, D. M. Lawton, J. Hoyland, 1993, International journal of experimental pathology.

Investigating the role of culture conditions on hypertrophic differentiation in human cartilage endplate cells

Safdar N. Khan, J. Hoyland, K. Lakstins, 2020, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Mature osteoblasts in human non-union fractures express collagen type III.

A. Freemont, D. Marsh, D. M. Lawton, 1997, Molecular pathology : MP.

Expression of the gene encoding the matrix gla protein by mature osteoblasts in human fracture non-unions.

A. Freemont, D. Marsh, D. M. Lawton, 1999, Molecular pathology : MP.

High BMPR2 expression leads to enhanced SMAD1/5/8 signalling and GDF6 responsiveness in human adipose-derived stem cells: implications for stem cell therapies for intervertebral disc degeneration

F. Wignall, S. Richardson, J. Hoyland, 2020, Journal of tissue engineering.

Microparticles for controlled growth differentiation factor 6 delivery to direct adipose stem cell‐based nucleus pulposus regeneration

K. Shakesheff, L. White, S. Richardson, 2019, Journal of tissue engineering and regenerative medicine.

Synthesis of polyacid nanogels: pH-responsive sub-100 nm particles for functionalisation and fluorescent hydrogel assembly.

S. Armes, A. Freemont, J. Hoyland, 2017, Soft matter.

Bi-Directional Exchange of Membrane Components Occurs during Co-Culture of Mesenchymal Stem Cells and Nucleus Pulposus Cells

S. Richardson, J. Hoyland, N. Hodson, 2012, PloS one.

Differential patterns of altered bone formation in different bone compartments in established osteoporosis.

A. Freemont, J. Hoyland, J. Denton, 1999, Journal of clinical pathology.

Differential patterns of osteoblast dysfunction in trabecular bone in patients with established osteoporosis.

A. Freemont, J. Hoyland, J. Denton, 1997, Journal of clinical pathology.

Plasmonic and colloidal stability behaviours of Au-acrylic core-shell nanoparticles with thin pH-responsive shells.

Matthias Karg, Dongdong Lu, Mingning Zhu, 2018, Nanoscale.

Expression of parathyroid hormone‐related protein and its receptor in bone metastases from prostate cancer

A. Freemont, J. Hoyland, N. Bundred, 2000, The Journal of pathology.

Anisotropic pH-Responsive Hydrogels Containing Soft or Hard Rod-Like Particles Assembled Using Low Shear

A. Miller, S. Armes, A. Freemont, 2017 .

NON-VIRAL REPROGRAMMING OF HUMAN NUCLEUS PULPOSUS CELLS WITH FOXF1 VIA EXTRACELLULAR VESICLE DELIVERY: AN IN VITRO AND IN VIVO STUDY

D. Gallego-Perez, J. Hoyland, D. Purmessur, 2021, European cells & materials.

Stem Cell Regeneration of Degenerated Intervertebral Discs: Current Status (Update)

S. Richardson, J. Hoyland, Hamish T. J. Gilbert, 2008, Current Pain and Headache Reports.

Mast cells in the pathogenesis of chronic back pain: a hypothesis

A. Freemont, J. Hoyland, Shant Kumar, 2002, The Journal of pathology.

Glucose Sensing in Chondrocytes via GLUT1 and GLUT3: Implications for Articular Cartilage and Intervertebral Disc Metabolism

A. Mobasheri, M. Shakibaei, S. Richardson, 2006 .

Self-curing super-stretchable polymer/microgel complex coacervate gels without covalent bond formation† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc02555c

S. Armes, Shangli Wu, J. Hoyland, 2019, Chemical science.

The differentiation of bone marrow mesenchymal stem cells into chondrocyte-like cells on poly-L-lactic acid (PLLA) scaffolds.

Judith M Curran, Stephen M Richardson, Rui Chen, 2006, Biomaterials.

Lumbar Intervertebral Disc Herniation: Annular Closure Devices and Key Design Requirements

J. Hoyland, G. Cooper, Andrew Weightman, 2022, Bioengineering.

Comparison of gene-expression profiles in parallel bone marrow and peripheral blood samples in acute myeloid leukaemia by real-time polymerase chain reaction

E. Tholouli, J. Hoyland, E. Sakhinia, 2006, Journal of Clinical Pathology.

A study of collagen gene expression in normally and abnormally healing human fractures

A. Freemont, D. Marsh, J. Hoyland, 1995 .

Fabrication of 3-dimensional cellular constructs via microstereolithography using a simple, three-component, poly(ethylene glycol) acrylate-based system.

James A Covington, Stephen M Richardson, Andrew P Dove, 2013, Biomacromolecules.

Visualising the 3D microstructure of stained and native intervertebral discs using X-ray microtomography

A. Bodey, J. Hoyland, P. Lee, 2017, Scientific Reports.

Harnessing the Potential of Mesenchymal Stem Cells for IVD Regeneration.

S. Richardson, J. Hoyland, Louise E. Clarke, 2015, Current stem cell research & therapy.

Core–Shell–Shell Nanoparticles for NIR Fluorescence Imaging and NRET Swelling Reporting of Injectable or Implantable Gels

M. Dickinson, J. Hoyland, B. Saunders, 2019, Biomacromolecules.

The use of a novel bone allograft wash process to generate a biocompatible, mechanically stable and osteoinductive biological scaffold for use in bone tissue engineering

J. Hoyland, T. Board, S. Richardson, 2015, Journal of tissue engineering and regenerative medicine.

Injectable doubly cross-linked microgels for improving the mechanical properties of degenerated intervertebral discs.

A. Freemont, J. Hoyland, B. Saunders, 2012, Biomacromolecules.

Expression of cartilage-derived morphogenetic protein in human intervertebral discs and its effect on matrix synthesis in degenerate human nucleus pulposus cells

A. Freemont, C. L. Le Maitre, J. Hoyland, 2009, Arthritis research & therapy.

Qualitative grading of disc degeneration by magnetic resonance in the lumbar and cervical spine: lack of correlation with histology in surgical cases

A. Freemont, J. Hoyland, B. Davies, 2016, British journal of neurosurgery.

Recommendations for intervertebral disc notochordal cell investigation: From isolation to characterization

C. L. Le Maitre, S. Richardson, J. Hoyland, 2023, JOR spine.

Aberrant P-cadherin expression is an early event in hyperplastic and dysplastic transformation in the colon

T. P. Pretlow, I. Talbot, J. Jankowski, 2002, Gut.

Open Access Research Article Expression of Semaphorin 3a and Its Receptors in the Human Intervertebral Disc: Potential Role in Regulating Neural Ingrowth in the Degenerate Intervertebral Disc

A. Freemont, S. Richardson, J. Hoyland, 2022 .

Current understanding of cellular and molecular events in intervertebral disc degeneration: implications for therapy

A. Freemont, J. Hoyland, J. Hoyland, 2002, The Journal of pathology.

Human notochordal cell transcriptome unveils potential regulators of cell function in the developing intervertebral disc

Stephen M Richardson, N. Hanley, S. Richardson, 2018, Scientific Reports.

Contribution of VCAF‐positive cells to neovascularization and calcification in atherosclerotic plaque development

J. Hoyland, A. Heagerty, J. Hoyland, 2007, The Journal of pathology.

Nucleic Acids: Subtractive Hybridization

A. Freemont, J. Hoyland, R. Byers, 2005 .

Plasmonic and colloidal stability behaviours of Au-acrylic core-shell nanoparticles with thin pH-responsive shells.

Shangli Wu, J. Hoyland, M. Karg, 2018, Nanoscale.

In situ-forming robust chitosan-poly(ethylene glycol) hydrogels prepared by copper-free azide-alkyne click reaction for tissue engineering.

V. Truong, S. Richardson, J. Hoyland, 2014, Biomaterials science.

Identification of novel nucleus pulposus markers

J. Hoyland, J. Hoyland, S. Richardson, 2013, Bone & joint research.

Responsive Nanogel Probe for Ratiometric Fluorescent Sensing of pH and Strain in Hydrogels.

A. Freemont, Shangli Wu, J. Hoyland, 2017, ACS macro letters.

Simultaneous orthogonal dual-click approach to tough, in-situ-forming hydrogels for cell encapsulation.

V. Truong, S. Richardson, J. Hoyland, 2015, Journal of the American Chemical Society.

Progenitor-like cells contributing to cellular heterogeneity in the nucleus pulposus are lost in intervertebral disc degeneration.

J. Hoyland, Peikai Chen, Zhijia Tan, 2024, Cell reports.

Molecular mechanisms of biological aging in intervertebral discs

James D. Kang, D. Kletsas, M. Risbud, 2016, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

From Multipotent Cells to Fully Differentiated Connective Tissue Cells for Regenerative Medicine: Emerging Applications of Mesenchymal Stem Cells

J. Hoyland, Constanze Buhrmann, Ali Mobasheri, 2012 .