Tian-yi Yuan

发表

Puerarin attenuates the endothelial-mesenchymal transition induced by oxidative stress in human coronary artery endothelial cells through PI3K/AKT pathway.

Xuguang Li, Shuchan Sun, Di Chen, 2020, European journal of pharmacology.

Synthesis of quaternary 8-(1-acylethene-1-yl)-13-methylcoptisine chlorides and their selective growth inhibitory activity between human cancer cell lines and normal intestinal epithelial cell-6

Tian-yi Yuan, L. Fang, G. Du, 2018 .

The strategies and techniques of drug discovery from natural products.

Tian-yi Yuan, Yang Lu, G. Du, 2020, Pharmacology & therapeutics.

Cardioprotective Effects of Puerarin-V on Isoproterenol-Induced Myocardial Infarction Mice Is Associated with Regulation of PPAR-Υ/NF-κB Pathway

Xuguang Li, Shuchan Sun, Tian-yi Yuan, 2018, Molecules.

Systematic analysis of molecular mechanism of resveratrol for treating pulmonary hypertension based on network pharmacology technology.

Di Chen, Tian-yi Yuan, Yu-cai Chen, 2020, European journal of pharmacology.

Systematic Elucidation of the Mechanism of Genistein against Pulmonary Hypertension via Network Pharmacology Approach

Di Chen, Tian-yi Yuan, Yu-cai Chen, 2019, International journal of molecular sciences.

DL0805-1, a novel Rho-kinase inhibitor, attenuates lung injury and vasculopathy in a rat model of monocrotaline-induced pulmonary hypertension.

Di Chen, Tian-yi Yuan, Yu-cai Chen, 2022, European journal of pharmacology.

Immunity and Inflammation in Pulmonary Arterial Hypertension: From Pathophysiology Mechanisms to Treatment Perspective.

Tian-yi Yuan, Yu-cai Chen, L. Fang, 2022, Pharmacological research.

Puerarin-V prevents the progression of hypoxia- and monocrotaline-induced pulmonary hypertension in rodent models

Di Chen, Tian-yi Yuan, L. Fang, 2022, Acta Pharmacologica Sinica.

Systems Pharmacology-Based Strategy to Investigate Pharmacological Mechanisms of Total Flavonoids in Dracocephalum moldavica on Chronic Heart Failure

Ling Zhang, Shuchan Sun, Tian-yi Yuan, 2022, International journal of molecular sciences.

The natural product bergenin ameliorates lipopolysaccharide-induced acute lung injury by inhibiting NF-kappaB activition.

Tian-yi Yuan, G. Du, Jinhua Wang, 2017, Journal of ethnopharmacology.

Mechanistic and therapeutic perspectives of baicalin and baicalein on pulmonary hypertension: A comprehensive review.

Tian-yi Yuan, Yu-cai Chen, Chenxi Liu, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Therapeutic effect of methyl salicylate 2-O-β-d-lactoside on LPS-induced acute lung injury by inhibiting TAK1/NF-kappaB phosphorylation and NLRP3 expression.

Tian-yi Yuan, G. Du, Lin Wang, 2016, International immunopharmacology.

Salvianolic acid A attenuates vascular remodeling in a pulmonary arterial hypertension rat model

Tian-yi Yuan, Yu-cai Chen, Dan-shu Wang, 2016, Acta Pharmacologica Sinica.

Inhibitory effects of Brazilin on the vascular smooth muscle cell proliferation and migration induced by PDGF-BB.

Tian-yi Yuan, L. Fang, G. Du, 2013, The American journal of Chinese medicine.

DL0805-2, a novel indazole derivative, relaxes angiotensin II-induced contractions of rat aortic rings by inhibiting Rho kinase and calcium fluxes

P. Xie, Tian-yi Yuan, Yu-cai Chen, 2016, Acta Pharmacologica Sinica.

Puerarin-V Improve Mitochondrial Respiration and Cardiac Function in a Rat Model of Diabetic Cardiomyopathy via Inhibiting Pyroptosis Pathway through P2X7 Receptors

Tian-yi Yuan, Yang Lu, Ranran Wang, 2022, International journal of molecular sciences.

Rho kinase inhibition activity of pinocembrin in rat aortic rings contracted by angiotensin II.

Tian-yi Yuan, G. Du, Yan Zhao, 2013, Chinese journal of natural medicines.

Fasudil evokes vasodilatation of rat mesenteric vascular bed via Ca(2+) channels and Rho/ROCK pathway.

Tian-yi Yuan, Yu-cai Chen, Dan-shu Wang, 2016, European journal of pharmacology.

Vasodilatory Effect of a Novel Rho-Kinase Inhibitor, DL0805-2, on the rat Mesenteric Artery and its Potential Mechanisms

P. Xie, Tian-yi Yuan, L. Fang, 2014, Cardiovascular Drugs and Therapy.

Network pharmacology approach and experimental verification of Dan-Shen Decoction in the treatment of ischemic heart disease

Shuchan Sun, Tian-yi Yuan, G. Du, 2022, Pharmaceutical biology.

Coptisine protects rat heart against myocardial ischemia/reperfusion injury by suppressing myocardial apoptosis and inflammation.

Tian-yi Yuan, L. Fang, G. Du, 2013, Atherosclerosis.

Discovery of Novel N-Substituted Prolinamido Indazoles as Potent Rho Kinase Inhibitors and Vasorelaxation Agents

Tian-yi Yuan, L. Fang, Ping Xie, 2017, Molecules.

Salvianolic acid A improve mitochondrial respiration and cardiac function via inhibiting apoptosis pathway through CRYAB in diabetic cardiomyopathy.

Tian-yi Yuan, L. Fang, Yang Lu, 2023, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

The comprehensive study on the therapeutic effects of baicalein for the treatment of COVID-19 in vivo and in vitro

Xiaozhong Peng, Tian-yi Yuan, Yang Lu, 2020, Biochemical Pharmacology.

The Potential of Traditional Chinese Medicine in the Treatment and Modulation of Pain.

Yongxiang Zhang, Tian-yi Yuan, G. Du, 2016, Advances in pharmacology.

Discovery of the neuroprotective effects of alvespimycin by computational prioritization of potential anti‐parkinson agents

Guan-Hua Du, Ai-Lin Liu, Jiansong Fang, 2014, The FEBS journal.

Activation of Nrf2 Attenuates Pulmonary Vascular Remodeling via Inhibiting Endothelial-to-Mesenchymal Transition: an Insight from a Plant Polyphenol

Tian-yi Yuan, Dan-shu Wang, L. Fang, 2017, International journal of biological sciences.

Rho kinase inhibition activity of pinocembrin in rat aortic rings contracted by angiotensin II: Rho kinase inhibition activity of pinocembrin in rat aortic rings contracted by angiotensin II

Tian-yi Yuan, G. Du, Yan Zhao, 2014 .

Vasorelaxant effect of quercetin on cerebral basilar artery in vitro and the underlying mechanisms study

Di Chen, Tian-yi Yuan, L. Fang, 2018, Journal of Asian natural products research.

Syntheses and structure-activity relationships in cytotoxicities of 13-substituted quaternary coptisine derivatives.

Tian-yi Yuan, L. Fang, G. Du, 2014, European journal of medicinal chemistry.