X. Dong

发表

Glaucocalyxin A exerts anticancer effect on osteosarcoma by inhibiting GLI1 nuclear translocation via regulating PI3K/Akt pathway

Jianwei Zhu, Yang Sun, Ying Lu, 2018, Cell Death & Disease.

Causal relationships between NAFLD, T2D and obesity have implications for disease subphenotyping.

C. Willer, R. Pique-Regi, Y. E. Chen, 2020, Journal of hepatology.

The construction and analysis of ceRNA network and patterns of immune infiltration in lung adenocarcinoma.

X. Dong, H. Bao, Yunfeng Dai, 2021, BMC cancer.

The construction and analysis of ceRNA network and patterns of immune infiltration in lung adenocarcinoma

X. Dong, E. Zhao, Hongguang Bao, 2021, BMC Cancer.

Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice.

X. Chen, Xiao-Ming Yin, X. Dong, 2013, Journal of hepatology.

The epigenetic regulator SIRT6 protects the liver from alcohol-induced tissue injury by reducing oxidative stress in mice.

X. Dong, J. Wan, Zhaoli Sun, 2019, Journal of hepatology.

Role of de Novo DNA Methyltransferases and Methyl CpG-binding Proteins in Gene Silencing in a Rat Hepatoma*

C. Plass, K. Ghoshal, J. Datta, 2002, The Journal of Biological Chemistry.

The potential of sestrins as therapeutic targets for diabetes

X. Dong, 2015, Expert opinion on therapeutic targets.

Abstract 3559: Insulin Receptor Substrates (IRS) Signaling are Essential Regulators of Mitochondrial Function and Cardiomyocyte Survival

M. White, X. Dong, E. Abel, 2008 .

Depdc5 deficiency exacerbates alcohol-induced hepatic steatosis via suppression of PPARα pathway

X. Dong, Zhaoli Sun, G. Hou, 2021, Cell Death & Disease.

Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function.

Sunmin Park, M. White, G. Weir, 2006, The Journal of biological chemistry.

Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.

B. Weimer, M. White, R. Gottlieb, 2013, The Journal of clinical investigation.

Mendelian Randomization Analysis Dissects the Relationship between NAFLD, T2D, and Obesity and Provides Implications to Precision Medicine

C. Willer, R. Pique-Regi, Y. E. Chen, 2019, bioRxiv.

Inhibitors of Histone Deacetylase and DNA Methyltransferase Synergistically Activate the Methylated Metallothionein I Promoter by Activating the Transcription Factor MTF-1 and Forming an Open Chromatin Structure

K. Ghoshal, J. Datta, S. Jacob, 2002, Molecular and Cellular Biology.

Mitochondrial Transcription Factor A and Its Downstream Targets Are Up-regulated in a Rat Hepatoma*

K. Ghoshal, S. Jacob, S. Majumder, 2002, The Journal of Biological Chemistry.

Suppression of Metallothionein Gene Expression in a Rat Hepatoma Because of Promoter-specific DNA Methylation*

K. Ghoshal, S. Jacob, S. Majumder, 2000, The Journal of Biological Chemistry.

IRS 2 increases mitochondrial dysfunction and oxidative stress in a mouse model of Huntington disease

D. Krainc, M. White, X. Dong, 2018 .

IRS2 increases mitochondrial dysfunction and oxidative stress in a mouse model of Huntington disease.

Zhiyong Cheng, Dimitri Krainc, D. Krainc, 2011, The Journal of clinical investigation.

Sesn3 deficiency promotes carcinogen-induced hepatocellular carcinoma via regulation of the hedgehog pathway.

X. Dong, Yunlong Liu, S. Liangpunsakul, 2019, Biochimica et biophysica acta. Molecular basis of disease.

Foxo1 integrates insulin signaling with mitochondrial function in the liver

P. Puigserver, R. DePinho, M. White, 2009, Nature Medicine.

Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation.

R. DePinho, Yedan Li, M. White, 2008, Cell metabolism.

Exendin-4 Uses Irs2 Signaling to Mediate Pancreatic β Cell Growth and Function*

Sunmin Park, M. White, G. Weir, 2006, Journal of Biological Chemistry.

PNPLA3—A Potential Therapeutic Target for Personalized Treatment of Chronic Liver Disease

X. Dong, 2019, Front. Med..

Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth.

Xueying Lin, Sunmin Park, M. White, 2006, The Journal of clinical investigation.

Genetic Inactivation of Pyruvate Dehydrogenase Kinases Improves Hepatic Insulin Resistance Induced Diabetes

Robert A. Harris, M. White, X. Dong, 2013, PloS one.

The Irs1 Branch of the Insulin Signaling Cascade Plays a Dominant Role in Hepatic Nutrient Homeostasis

Sunmin Park, M. White, Shaodong Guo, 2009, Molecular and Cellular Biology.

A high-fat diet catalyzes progression to hyperglycemia in mice with selective impairment of insulin action in Glut4-expressing tissues

Jason M. Conley, A. Robling, X. Dong, 2021, The Journal of biological chemistry.

Abstract 3992: Insulin Receptor Substrates (IRS) are Critical Regulators of Autophagy and Cardiomyocyte Survival

A. Moon, M. White, R. Gottlieb, 2009 .

A highly selective and potent PTP-MEG2 inhibitor with therapeutic potential for type 2 diabetes.

David R. Jones, X. Dong, Zhon-Yin Zhang, 2012, Journal of the American Chemical Society.

Glaucocalyxin A exerts anticancer effect on osteosarcoma by inhibiting GLI1 nuclear translocation via regulating PI3K/Akt pathway

Jianwei Zhu, Yang Sun, Ying Lu, 2018, Cell Death & Disease.

The Repression of IRS2 Gene by ATF3, a Stress-Inducible Gene, Contributes to Pancreatic β-Cell Apoptosis

Tsonwin Hai, M. White, E. Zmuda, 2008, Diabetes.

Oridonin exerts anticancer effect on osteosarcoma by activating PPAR-γ and inhibiting Nrf2 pathway

Jianwei Zhu, Yang Sun, Ying Lu, 2018, Cell Death & Disease.

High performance liquid chromatography-mass spectrometry/mass spectrometry (HPLC-MS/MS) analysis of transmembrane transport characteristics of nuciferine in Caco-2 cells

X. Dong, J. Ge, Zong-Mu Dong, 2021 .

Phosphorylation of Irs1 at SER-522 inhibits insulin signaling.

M. White, X. Dong, E. Feener, 2007, Molecular endocrinology.

Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.

B. Weimer, M. White, R. Gottlieb, 2013, The Journal of clinical investigation.