B. Harbrecht

发表

MicroRNA-203 suppresses proliferation in liver cancer associated with PIK3CA, p38 MAPK, c-Jun, and GSK3 signaling

A. Zhang, J. Lakshmanan, Amirreza T. Motameni, 2018, Molecular and Cellular Biochemistry.

Correlating Geographic Location with Incidence of Motor Vehicle–Induced Pedestrian Injury

B. Harbrecht, N. Bhutiani, K. Miller, 2018, The American surgeon.

Correlating Geographic Location with Incidence of Motor Vehicle–Induced Pedestrian Injury

B. Harbrecht, N. Bhutiani, K. Miller, 2018, The American surgeon.

Cyclic GMP and guanylate cyclase mediate lipopolysaccharide‐induced Kupffer cell tumor necrosis factor‐α synthesis

T. Billiar, B. Harbrecht, S. C. Wang, 1995, Journal of leukocyte biology.

Tumor necrosis factor‐α regulates in vivo nitric oxide synthesis and induces liver injury during endotoxemia

T. Billiar, A. Demetris, B. Harbrecht, 1994 .

Characterization of unexpected survivors following a prehospital plasma randomized trial

F. Guyette, J. Sperry, B. Harbrecht, 2020, The journal of trauma and acute care surgery.

Anti-HMGB 1 Neutralizing Antibody Ameliorates Gut Barrier Dysfunction and Improves Survival after Hemorrhagic Shock

K. Tracey, Huan Yang, M. Fink, 2006 .

Anti-HMGB1 Neutralizing Antibody Ameliorates Gut Barrier Dysfunction and Improves Survival after Hemorrhagic Shock

K. Tracey, Huan Yang, M. Fink, 2006, Molecular medicine.

Not All Abdomens Are the Same: A Comparison of Damage Control Surgery for Intra-abdominal Sepsis versus Trauma

B. Harbrecht, A. Bernard, K. Miller, 2016, The American surgeon.

Interhospital transfer of blunt multiply injured patients to a level 1 trauma center does not adversely affect outcome.

D. Trunkey, B. Harbrecht, G. Franklin, 2014, American journal of surgery.

Endogenous nitric oxide inhibits the synthesis of cyclooxygenase products and interleukin‐6 by rat Kupffer cells

T. Billiar, B. Harbrecht, M. Jordan, 1993, Journal of leukocyte biology.

Neutrophil accumulation and damage to the gastric mucosa in resuscitated hemorrhagic shock is independent of inducible nitric oxide synthase.

T. Billiar, K. Tsukada, B. Harbrecht, 1999, Shock.

Insulin inhibits hepatocyte iNOS expression induced by cytokines by an Akt-dependent mechanism.

B. Harbrecht, Jason W. Smith, Baochun Zhang, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Control of Glucose after Injury

B. Harbrecht, 2008, The American surgeon.

The use of ABC score in activation of massive transfusion: The yin and the yang

Amirreza T. Motameni, B. Harbrecht, K. Miller, 2018, The journal of trauma and acute care surgery.

Nitric oxide and prostaglandins interact to prevent hepatic damage during murine endotoxemia.

T. Billiar, A. Demetris, B. Harbrecht, 1994, The American journal of physiology.

Improved outcomes with routine respiratory therapist evaluation of non-intensive-care-unit surgery patients.

M. Saul, Cynthia A Valenta, B. Harbrecht, 2009, Respiratory care.

Differential effects of nonselective nitric oxide synthase (NOS) and selective inducible NOS inhibition on hepatic necrosis, apoptosis, ICAM-1 expression, and neutrophil accumulation during endotoxemia.

Simon C Watkins, T. Billiar, J. Saavedra, 1997, Nitric oxide : biology and chemistry.

Dose-dependent association between blood transfusion and nosocomial infections in trauma patients: A secondary analysis of patients from the PAMPer trial

F. Guyette, J. Sperry, H. Ladhani, 2021, The journal of trauma and acute care surgery.

Evaluating the Cost-effectiveness of Prehospital Plasma Transfusion in Unstable Trauma Patients: A Secondary Analysis of the PAMPer Trial.

F. Guyette, J. Sperry, B. Harbrecht, 2021, JAMA surgery.

Massive transfusion and the response to prehospital plasma: It is all in how you define it

F. Guyette, J. Sperry, B. Harbrecht, 2020, The journal of trauma and acute care surgery.

Prehospital plasma is associated with distinct biomarker expression following injury.

F. Guyette, Y. Vodovotz, J. Sperry, 2020, JCI insight.

SEVERITY OF HEMORRHAGE AND THE SURVIVAL BENEFIT ASSOCIATED WITH PLASMA: RESULTS FROM A RANDOMIZED PREHOSPITAL PLASMA TRIAL.

F. Guyette, J. Sperry, B. Harbrecht, 2019, The journal of trauma and acute care surgery.

Prehospital Blood Product and Crystalloid Resuscitation in the Severely Injured Patient: A Secondary Analysis of the Prehospital Air Medical Plasma Trial.

A. Peitzman, F. Guyette, J. Sperry, 2019, Annals of surgery.

Changes in massive transfusion over time: An early shift in the right direction?

A. Peitzman, J. Minei, J. Sperry, 2012, The journal of trauma and acute care surgery.

Glycogen Synthase Kinase 3 Regulates IL‐1β Mediated iNOS Expression in Hepatocytes by Down‐Regulating c‐Jun

J. Lakshmanan, B. Harbrecht, Baochun Zhang, 2015, Journal of cellular biochemistry.

Effective triage can ameliorate the deleterious effects of delayed transfer of trauma patients from the emergency department to the ICU.

J. Richardson, K. McMasters, B. Harbrecht, 2009, Journal of the American College of Surgeons.

Is Obesity Protective in Thoracoabdominal Penetrating Trauma?

B. Harbrecht, Matthew V. Benns, Nicholas A. Nash, 2019, The American surgeon.

Taking the Blood Bank to the Field: The Design and Rationale of the Prehospital Air Medical Plasma (PAMPer) Trial

A. Peitzman, F. Guyette, J. Sperry, 2015, Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors.

Crystalloid to packed red blood cell transfusion ratio in the massively transfused patient: When a little goes a long way

A. Peitzman, J. Minei, J. Sperry, 2012, The journal of trauma and acute care surgery.

Nonoperative management of severe blunt splenic injury: are we getting better?

A. Peitzman, M. Rosengart, B. Harbrecht, 2005, The Journal of trauma.

Is anything new in adult blunt splenic trauma?

B. Harbrecht, 2005, American journal of surgery.

Failure of observation of blunt splenic injury in adults: variability in practice and adverse consequences.

A. Peitzman, B. Harbrecht, B. Heil, 2005, Journal of the American College of Surgeons.

Coronary Syndromes, Acute

B. Abella, R. Bellomo, D. Trunkey, 2012 .

Impact of Hollow Viscus Injuries on Outcome of Abdominal Gunshot Wounds

J. Richardson, B. Harbrecht, G. Franklin, 2009, The American surgeon.

Organ donation as an outcome of traumatic cardiopulmonary arrest: A cost evaluation

B. Harbrecht, K. Miller, Matthew V. Benns, 2016, The journal of trauma and acute care surgery.

Calcium-mediated signaling and calmodulin-dependent kinase regulate hepatocyte-inducible nitric oxide synthase expression.

J. Lakshmanan, B. Harbrecht, Baochun Zhang, 2015, The Journal of surgical research.

TRISS unexpected survivors: an outdated standard?

A. Peitzman, T. Fabian, A. Courcoulas, 1999, Journal of Trauma.

Akt-mediated signaling is induced by cytokines and cyclic adenosine monophosphate and suppresses hepatocyte inducible nitric oxide synthase expression independent of MAPK P44/42.

B. Harbrecht, Baochun Zhang, Suping Li, 2011, Biochimica et biophysica acta.

Hypoxia-inducible factor-1 activation and cyclo-oxygenase-2 induction are early reperfusion-independent inflammatory events in hemorrhagic shock

D. Tweardy, T. Billiar, B. Harbrecht, 2001, Archives of Orthopaedic and Trauma Surgery.

Decreasing regional neurosurgical workforce-a blueprint for disaster.

J. Richardson, B. Harbrecht, G. Franklin, 2010, The Journal of trauma.

The limitations of hospital and law enforcement databases in characterizing the epidemiology of firearm injury

M. Egger, B. Harbrecht, K. Miller, 2021, The journal of trauma and acute care surgery.

Percutaneous endoscopic gastrostomy reduces total hospital costs in head-injured patients.

M. Saul, A. Courcoulas, B. Harbrecht, 1998, American journal of surgery.

Inflammation and the host response to injury, a large-scale collaborative project: patient-oriented research core-standard operating procedures for clinical care: VI. Blood glucose control in the critically ill trauma patient.

J. Minei, A. Nathens, E. Moore, 2007, The Journal of trauma.

A New Pandemic and an Old Epidemic – The Impact of COVID-19 and Gun Violence as Measured by Years of Potential Life Lost in a US City

B. Harbrecht, N. Bhutiani, K. Miller, 2022, Surgery.

LPS- or IFN-y-induced macrophage NO synthesis by PGE2

T. Billiar, B. Harbrecht, R. Simmons, 1997 .

Timing of prostaglandin exposure is critical for the inhibition of LPS‐ or IFN‐γ‐induced macrophage NO synthesis by PGE2

T. Billiar, B. Harbrecht, R. Simmons, 1997, Journal of leukocyte biology.

17&bgr;-Estradiol attenuates cytokine-induced nitric oxide production in rat hepatocyte

C. Klinge, J. Lakshmanan, B. Harbrecht, 2012, The journal of trauma and acute care surgery.

Reduced hepatic transcription factor activation and expression of IL-6 and ICAM-1 after hemorrhage by NO scavening

D. Tweardy, T. Billiar, B. Harbrecht, 2003, Archives of Orthopaedic and Trauma Surgery.

Tumor necrosis factor alpha inhibits hepatocyte mitochondrial respiration.

T. Billiar, B. Harbrecht, R. Simmons, 1992, Annals of surgery.

Association of Prehospital Plasma Transfusion With Survival in Trauma Patients With Hemorrhagic Shock When Transport Times Are Longer Than 20 Minutes: A Post Hoc Analysis of the PAMPer and COMBAT Clinical Trials.

James G. Chandler, A. Sauaia, F. Guyette, 2019, JAMA surgery.

Cyclic AMP inhibits IL-1beta plus IFNgamma-induced NF-kappaB translocation in hepatocytes by a PKA independent mechanism.

B. Harbrecht, Baochun Zhang, G. Hong, 2010, The Journal of surgical research.

Cyclic AMP Inhibits IL-1 β Plus IFN γ -Induced NF- κ B Translocation in Hepatocytes by a PKA Independent Mechanism

B. Harbrecht, Baochun Zhang, G. Hong, 2010 .

The Modulation of Hepatic Injury and Heat Shock Expression by Inhibition of Inducible Nitric Oxide Synthase After Hemorrhagic Shock

Simon C Watkins, A. Peitzman, T. Billiar, 2002, Shock.

Article Commentary: Thoracolumbar Spine Trauma: Diagnostic and Therapeutic Considerations for the General Surgeon

B. Harbrecht, M. Djurasovic, 2009, The American surgeon.

Prostanoids inhibit Kupffer cell nitric oxide synthesis.

T. Billiar, B. Harbrecht, R. Simmons, 1995, The Journal of surgical research.

Cyclic AMP regulate adenovirus mediated inducible nitric oxide synthase expression and CMV promoter activity in cultured hepatocytes.

B. Harbrecht, Baochun Zhang, Ye Liu, 2003, Nitric oxide : biology and chemistry.

Safety of De-Escalating Empiric Antimicrobial Agents in Trauma Patients with Indigenous Oral Flora Ventilator-Associated Pneumonia.

B. Harbrecht, Chelsey M. McPheeters, L. Scherrer, 2022, Surgical infections.

Nitric Oxide Regulates Prostaglandin E2 Release by Rat Kupffer Cells

T. Billiar, B. Harbrecht, R. Simmons, 1993 .

Inhibition of nitric oxide synthesis during endotoxemia promotes intrahepatic thrombosis and an oxygen radical‐mediated hepatic injury

T. Billiar, A. Demetris, B. Harbrecht, 1992, Journal of leukocyte biology.

Lipidomic Signatures Align with Inflammatory Patterns and Outcomes in Critical Illness

Upendra K. Kar, C. Callaway, A. Cyr, 2021, Nature Communications.

Early use of vasopressors after injury: caution before constriction.

J. Minei, H. Frankel, J. Sperry, 2008, The Journal of trauma.

cAMP inhibits inducible nitric oxide synthase expression and NF-kappaB-binding activity in cultured rat hepatocytes.

B. Harbrecht, D. Geller, R. Ganster, 2001, The Journal of surgical research.

Inflammation and the host response to injury, a Large-Scale Collaborative Project: patient-oriented research core standard operating procedures for clinical care IX. Definitions for complications of clinical care of critically injured patients.

J. Minei, H. Evans, A. Nathens, 2009, The Journal of trauma.

Statewide experience with Clostridium difficile colitis in academic and non-academic medical centers.

J. Richardson, B. Harbrecht, G. Franklin, 2012, Surgical infections.

Therapeutic use of nitric oxide scavengers in shock and sepsis.

B. Harbrecht, 2006, Current pharmaceutical design.

The practice of venous thromboembolism prophylaxis in the major trauma patient.

R. Tompkins, J. Minei, A. Nathens, 2007, The Journal of trauma.

Interactions between fatty acids and arginine metabolism: implications for the design of immune-enhancing diets.

B. Harbrecht, J. Ochoa, V. Bansal, 2005, JPEN. Journal of parenteral and enteral nutrition.

Inflammation and the host response to injury a large-scale collaborative project: patient-oriented research core standard operating procedure for clinical care X. Guidelines for venous thromboembolism prophylaxis in the trauma patient.

G. O’Keefe, J. Minei, J. Sperry, 2008, The Journal of trauma.

JNK signaling involved in the effects of cyclic AMP on IL-1β plus IFNγ-induced inducible nitric oxide synthase expression in hepatocytes

B. Harbrecht, Baochun Zhang, Michele Perpetua, 2004 .

GLUCAGON REGULATES HEPATIC INDUCIBLE NITRIC OXIDE SYNTHESIS IN VIVO

B. Harbrecht, Baochun Zhang, M. Fulmer, 2004, Shock.

Early VATS for blunt chest trauma: a management technique underutilized by acute care surgeons.

J. Richardson, B. Harbrecht, G. Franklin, 2011, The Journal of trauma.

Cytokines increase CRE binding but decrease CRE‐mediated reporter activity in rat hepatocytes by increasing c‐Jun

B. Harbrecht, W. Walker, Baochun Zhang, 2004, Hepatology.

Hepatic resection in the management of complex injury to the liver.

A. Peitzman, J. Puyana, B. Harbrecht, 2008, The Journal of trauma.

Direct peritoneal resuscitation accelerates primary abdominal wall closure after damage control surgery.

J. Richardson, B. Harbrecht, G. Franklin, 2010, Journal of the American College of Surgeons.

Induced nitric oxide promotes intestinal inflammation following hemorrhagic shock.

D. Tweardy, T. Billiar, B. Harbrecht, 2004, American journal of physiology. Gastrointestinal and liver physiology.

Inhibition of nitric oxide synthase during hemorrhagic shock increases hepatic injury.

Simon C Watkins, A. Peitzman, T. Billiar, 1995, Shock.

Tender Coconut Water Protects Mice From Ischemia-Reperfusion-Mediated Liver Injury and Secondary Lung Injury

J. Lakshmanan, B. Harbrecht, Baochun Zhang, 2021, Shock.

PGE2 and LTB4 inhibit cytokine-stimulated nitric oxide synthase type 2 expression in isolated rat hepatocytes.

T. Billiar, B. Harbrecht, R. Shapiro, 1996, Prostaglandins.

A Review of “Predicting the Need to Pack Early for Severe Intra-abdominal Hemorrhage” (1996)

B. Harbrecht, 2021, The American surgeon.

Glucagon inhibits hepatocyte nitric oxide synthesis.

T. Billiar, B. Harbrecht, Y. M. Kim, 1996, Archives of surgery.

Evaluation of a 15-year experience with splenic injuries in a state trauma system.

A. Peitzman, J. Puyana, B. Harbrecht, 2007, Surgery.

Resveratrol decreases nitric oxide production by hepatocytes during inflammation.

J. Lakshmanan, B. Harbrecht, Matthew V. Benns, 2015, Surgery.

Acute appendicitis--not just for the young.

J. Richardson, B. Harbrecht, G. Franklin, 2011, American journal of surgery.

Optimization of Donor Management Goals Yields Increased Organ Use

B. Harbrecht, G. Franklin, Jason W. Smith, 2010, The American surgeon.

Intubated Trauma Patients Do Not Require Full Trauma Team Activation when Effectively Triaged.

J. Richardson, B. Harbrecht, K. Miller, 2016, Journal of the American College of Surgeons.

Two unique aspects of inducible .N = O synthase in liver cells and accessory cells: hepatic damage is minimized by hepatocyte .N = O production and immunoregulation is mediated by macrophage .N = O production.

T. Billiar, B. Harbrecht, R. Simmons, 1991, Research in immunology.

Use of Computed Tomography Findings and Contrast Extravasation in Predicting the Need for Embolization with Pelvic Fractures

J. Richardson, B. Harbrecht, G. Franklin, 2012, The American surgeon.

Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock

C. Callaway, A. Peitzman, D. Yealy, 2018, The New England journal of medicine.

Prevention of Bile Peritonitis by Laparoscopic Evacuation and Lavage after Nonoperative Treatment of Liver Injuries

J. Richardson, B. Harbrecht, G. Franklin, 2007, The American surgeon.

Angiography for blunt splenic trauma does not improve the success rate of nonoperative management.

A. Peitzman, M. Rosengart, B. Harbrecht, 2007, The Journal of trauma.

The changing pattern and implications of multiple organ failure after blunt injury with hemorrhagic shock*

R. Tompkins, G. O’Keefe, L. Moldawer, 2012, Critical care medicine.

Modulation of Nitrogen Oxide Synthesis In Vivo: NG‐Monomethyl‐L‐Arginine Inhibits Endotoxin‐Induced Nitrate/Nitrate Biosynthesis While Promoting Hepatic Damage

R. L. Simmons, T. Billiar, B. Harbrecht, 1990, Journal of leukocyte biology.

American College of Surgeons and Surgical Infection Society: Surgical Site Infection Guidelines, 2016 Update.

E. P. Dellinger, K. Itani, C. Ko, 2017, Journal of the American College of Surgeons.

Application of genome-wide expression analysis to human health and disease.

Mehmet Toner, Gregory Stephanopoulos, Wenzhong Xiao, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Bcl‐xL prevents staurosporine‐induced hepatocyte apoptosis by restoring protein kinase B/mitogen‐activated protein kinase activity and mitochondria integrity

B. Harbrecht, Ximei Peng, Yinna Wang, 2008, Journal of cellular physiology.

Early blood product and crystalloid volume resuscitation: risk association with multiple organ dysfunction after severe blunt traumatic injury.

Steven S. Henley, R. Golden, T. M. Kashner, 2011, The Journal of trauma.

Cytochrome P-450 activity is differentially altered in severely injured patients

A. Peitzman, R. Branch, B. Harbrecht, 2005, Critical care medicine.

V. Guidelines for sedation and analgesia during mechanical ventilation general overview.

J. Minei, A. Nathens, E. Moore, 2007, The Journal of trauma.

Recidivism Rates Following Firearm Injury as Determined by a Collaborative Hospital and Law Enforcement Database.

Michael E. Egger, J. Richardson, M. Egger, 2020, The journal of trauma and acute care surgery.

Self-Inflicted Stab Wounds: A Single-Center Experience from 2010 to 2016

B. Harbrecht, N. Bhutiani, Matthew V. Benns, 2019, The American Surgeon.

Adjunctive treatment of abdominal catastrophes and sepsis with direct peritoneal resuscitation: Indications for use in acute care surgery

B. Harbrecht, Matthew V. Benns, G. Franklin, 2014, The journal of trauma and acute care surgery.

Executive Summary of the American College of Surgeons/Surgical Infection Society Surgical Site Infection Guidelines-2016 Update.

E. P. Dellinger, K. Itani, C. Ko, 2017, Surgical infections.

The evolving management of venous bullet emboli: a case series and literature review.

B. Harbrecht, Matthew V. Benns, G. Franklin, 2011, Injury.

Nitric oxide synthesis serves to reduce hepatic damage during acute murine endotoxemia

T. Billiar, A. Demetris, B. Harbrecht, 1992, Critical care medicine.

Prehospital plasma in injured patients is associated with survival principally in blunt injury: Results from two randomized prehospital plasma trials

A. Sauaia, F. Guyette, J. Sperry, 2019, The journal of trauma and acute care surgery.

A brief episode of hypotension increases mortality in critically ill trauma patients.

Timothy R Billiar, Mazen S Zenati, A. Peitzman, 2002, The Journal of trauma.

Essential Role of Induced Nitric Oxide in the Initiation of the Inflammatory Response after Hemorrhagic Shock

A. Peitzman, D. Tweardy, T. Billiar, 1998, The Journal of experimental medicine.

Inflammation and the Host Response to Injury, a large-scale collaborative project: patient-oriented research core--standard operating procedures for clinical care. III. Guidelines for shock resuscitation.

J. Minei, A. Nathens, E. Moore, 2006, The Journal of trauma.

INHIBITION OF NITRIC OXIDE SYNTHESIS DURING SEVERE SHOCK BUT NOT AFTER RESUSCITATION INCREASES HEPATIC INJURY AND NEUTROPHIL ACCUMULATION IN HEMORRHAGED RATS

Simon C Watkins, A. Peitzman, T. Billiar, 1995, Shock.

Plasma resuscitation with adjunctive peritoneal resuscitation reduces ischemia-induced intestinal barrier breakdown following hemorrhagic shock

B. Harbrecht, Jason W. Smith, P. Matheson, 2020, The journal of trauma and acute care surgery.

Plasma resuscitation with adjunctive peritoneal resuscitation reduces ischemic intestinal injury following hemorrhagic shock

B. Harbrecht, Jason W. Smith, P. Matheson, 2020, The journal of trauma and acute care surgery.

Early supplemental parenteral nutrition is associated with increased infectious complications in critically ill trauma patients.

Joseph Cuschieri, Garth H Utter, Ernest E Moore, 2008, Journal of the American College of Surgeons.

Laparoscopic cholecystectomy in the transplant population

A. Courcoulas, B. Harbrecht, E. Kelly, 1996, Surgical Endoscopy.

Multiple cytokines are required to induce hepatocyte nitric oxide production and inhibit total protein synthesis.

T. Billiar, B. Harbrecht, R. Simmons, 1990, Annals of surgery.

Direct peritoneal resuscitation reduces intestinal permeability after brain death

B. Harbrecht, Jason W. Smith, J. Weaver, 2017, The journal of trauma and acute care surgery.

UTILITY OF CLINICAL PARAMETERS OF TISSUE OXYGENATION IN A QUANTITATIVE MODEL OF IRREVERSIBLE HEMORRHAGIC SHOCK

A. Peitzman, T. Billiar, B. Harbrecht, 1998, Shock.

improves survival after hemorrhagic shock A novel nitric oxide scavenger decreases liver injury and

Simon C Watkins, D. Tweardy, T. Billiar, 2016 .

A novel nitric oxide scavenger decreases liver injury and improves survival after hemorrhagic shock.

Simon C Watkins, A. Peitzman, D. Tweardy, 1999, The American journal of physiology.

Roles for Induced Nitric Oxide in Endotoxic and Hemorrhagic Shock

T. Billiar, B. Harbrecht, R. T. Villavicencio, 1999 .

Does chest tube location matter? An analysis of chest tube position and the need for secondary interventions

Michael E. Egger, J. Richardson, M. Egger, 2015, The journal of trauma and acute care surgery.

Flail Chest Injury: Are We Making Any Progress?

J. Richardson, B. Harbrecht, G. Franklin, 2012, The American surgeon.

Damage Control for Thoracic Trauma

J. Richardson, B. Harbrecht, Matthew V. Benns, 2014, The American surgeon.

Chest Tube Placement, Care, and Removal

B. Harbrecht, G. Watson, 2011 .

Hypothermia in massive transfusion: Have we been paying enough attention to it?

A. Peitzman, J. Minei, J. Sperry, 2012, The journal of trauma and acute care surgery.

A Genomic Score Prognostic of Outcome in Trauma Patients

Ronald G. Tompkins, David A. Schoenfeld, Celeste C. Finnerty, 2009, Molecular medicine.

Socioeconomic disparities in the operative management of peptic ulcer disease.

B. Harbrecht, Matthew V. Benns, G. Franklin, 2013, Surgery.

Cell-specific regulation of iNOS by AMP-activated protein kinase in primary rat hepatocytes.

J. Lakshmanan, B. Harbrecht, Jason W. Smith, 2018, The Journal of surgical research.

Multi-omic analysis in injured humans: Patterns align with outcomes and treatment responses

Upendra K. Kar, S. Wisniewski, A. Cyr, 2021, Cell reports. Medicine.

A Systemic Storm in Critically Injured Humans Revealed by Longitudinal Multi-Omics

Upendra K. Kar, S. Wisniewski, A. Cyr, 2021 .

Fresh frozen plasma is independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome.

A. Peitzman, M. Rosengart, J. Minei, 2009, The Journal of trauma.

Fulminant Clostridium difficile: An Underappreciated and Increasing Cause of Death and Complications

C. Sirio, B. Harbrecht, R. Simmons, 2002, Annals of surgery.

Assessment of transcutaneous bilirubinometry in hospitalized adults.

M. Rosengart, B. Harbrecht, D. Geller, 2008, Journal of the American College of Surgeons.

Predicting outcome in patients with acute liver failure: what works best?

B. Harbrecht, 2012, Critical care medicine.

Patients with Abrasion or Ecchymosis Seat Belt Sign Have High Risk for Abdominal Injury, but Initial Computed Tomography is 100% Sensitive.

B. Harbrecht, Nicholas A. Nash, M. Huecker, 2020, The Journal of emergency medicine.

The prevalence and impact of prescription controlled substance use among injured patients at a Level I trauma center

B. Harbrecht, Matthew V. Benns, G. Franklin, 2014, The journal of trauma and acute care surgery.

Early Enteral Nutrition in Trauma: Is There Still Any Doubt?

B. Harbrecht, Matthew V. Benns, Jason W. Smith, 2016, Current Trauma Reports.

Hepatic dysfunction increases length of stay and risk of death after injury.

A. Peitzman, J. McMichael, B. Harbrecht, 2002, The Journal of trauma.

The Impact of Liver Dysfunction on Outcome in Patients with Multiple Injuries

A. Peitzman, T. Billiar, B. Harbrecht, 2001, The American surgeon.

Defining the Contribution of Renal Dysfunction to Outcome after Traumatic Injury

A. Peitzman, M. Rosengart, B. Harbrecht, 2007, The American surgeon.

B. Harbrecht, Matthew V. Benns, Nicholas A. Nash, 2017, The American surgeon.

Evaluating the early impact of Medicaid expansion on trends in diagnosis and treatment of benign gallbladder disease in Kentucky.

C. Scoggins, B. Harbrecht, N. Bhutiani, 2019, American journal of surgery.

Management of adult blunt splenic injuries: comparison between level I and level II trauma centers.

A. Peitzman, J. Puyana, B. Harbrecht, 2004, Journal of the American College of Surgeons.

Is Splenectomy after Trauma an Endangered Species?

J. Richardson, B. Harbrecht, G. Franklin, 2008, The American surgeon.

Blunt Liver Injury in Children and Adults: Is There Really a Difference?

J. Richardson, B. Harbrecht, G. Franklin, 2008, The American surgeon.

Is Outcome after Blunt Splenic Injury in Adults Better in High-Volume Trauma Centers?

A. Peitzman, J. Puyana, B. Harbrecht, 2005, The American surgeon.

Risk factors and outcome of acute kidney injury in elderly trauma patients.

B. Harbrecht, Nicholas A. Nash, Kimberly Broughton-Miller, 2019, American journal of surgery.

Central Line-Associated Blood Stream Infection in the Critically Ill Trauma Patient

J. Richardson, M. Egger, B. Harbrecht, 2011, The American surgeon.

Inflammation and the host response to injury, a large-scale collaborative project: patient-oriented research core--standard operating procedures for clinical care VII--Guidelines for antibiotic administration in severely injured patients.

J. Minei, A. Nathens, E. Moore, 2008, The Journal of trauma.

Danger on the Farm: A Comparison of Agricultural and Animal-Related Injuries

B. Harbrecht, Nicholas A. Nash, M. Bozeman, 2017, The American surgeon.

Fall, Crush, Kick: Mechanisms and Outcomes in a Cohort of Equine-Related Injuries.

B. Harbrecht, Nicholas A. Nash, M. Huecker, 2021, The American surgeon.

Inflammation and the Host Response to Injury, a Large-Scale Collaborative Project: patient-oriented research core--standard operating procedures for clinical care. II. Guidelines for prevention, diagnosis and treatment of ventilator-associated pneumonia (VAP) in the trauma patient.

J. Minei, A. Nathens, E. Moore, 2006, The Journal of trauma.

II. Guidelines for Prevention, Diagnosis and Treatment of Ventilator-Associated Pneumonia (VAP) in the Trauma

A. Nathens, E. Moore, R. Maier, 2006 .

Association between synthesis and release of cGMP and nitric oxide biosynthesis by hepatocytes.

T. Billiar, B. Harbrecht, R. Simmons, 1992, The American journal of physiology.

The impact of historical racism on modern gun violence: Redlining in the city of Louisville, KY.

B. Harbrecht, Matthew V. Benns, Nicholas A. Nash, 2020, Injury.

Male gender is associated with excessive IL-6 expression following severe injury.

A. Peitzman, J. Minei, H. Frankel, 2008, The Journal of trauma.

Body adipose content is independently associated with a higher risk of organ failure and nosocomial infection in the nonobese patient postinjury.

A. Peitzman, M. Rosengart, J. Minei, 2011, The Journal of trauma.

Evaluation of critical care burden following traumatic injury from two randomized controlled trials

F. Guyette, J. Sperry, B. Harbrecht, 2023, Scientific Reports.

Time to early resuscitative intervention association with mortality in trauma patients at risk for hemorrhage

F. Guyette, J. Sperry, B. Harbrecht, 2023, The journal of trauma and acute care surgery.

High Dimensional Multiomics Reveals Unique Characteristics of Early Plasma Administration in Polytrauma Patients With TBI

Upendra K. Kar, F. Guyette, J. Sperry, 2022, Annals of surgery.

Prehospital plasma is associated with survival principally in patients transferred from the scene of injury: A secondary analysis of the PAMPer trial.

F. Guyette, J. Sperry, B. Harbrecht, 2022, Surgery.

Association of Prehospital Plasma With Survival in Patients With Traumatic Brain Injury

F. Guyette, D. Okonkwo, J. Sperry, 2020, JAMA network open.

Age of thawed plasma does not affect clinical outcomes or biomarker expression in patients receiving prehospital thawed plasma: a PAMPer secondary analysis

Y. Vodovotz, J. Sperry, B. Harbrecht, 2021, Trauma Surgery & Acute Care Open.

Prehospital Blood Product and Crystalloid Resuscitation in the Severely Injured Patient: A Secondary Analysis of the Prehospital Air Medical Plasma Trial.

A. Peitzman, F. Guyette, J. Sperry, 2019, Annals of Surgery.

Stop the Bleed: Is Mass Education the Best Approach?

Amirreza T. Motameni, B. Harbrecht, Matthew V. Benns, 2018, The American surgeon.

Effect of endogenous nitric oxide on mitochondrial respiration of rat hepatocytes in vitro and in vivo.

T. Billiar, B. Harbrecht, R. Simmons, 1991, Archives of surgery.

The role of nitric oxide in Kupffer cell-hepatocyte interactions.

T. Billiar, B. Harbrecht, 1995, Shock.

The Geography of Injuries in Trauma Systems: Using Home as a Proxy for Incident Location.

Mayur B. Patel, Daniel G. Ostermayer, F. Guyette, 2023, The Journal of surgical research.

Trauma center maturation: quantification of process and outcome.

A. Peitzman, A. Courcoulas, T. Billiar, 1999, Annals of surgery.

Traumatic Injury May Be a Predisposing Factor for Cerebrovascular Accident

B. Harbrecht, Matthew V. Benns, G. Franklin, 2013, Journal of trauma nursing : the official journal of the Society of Trauma Nurses.

Inflammation and the host response to injury, a large-scale collaborative project: Patient-oriented research core - Standard operating procedures for clinical care. Foreward

R. Tompkins, J. Minei, A. Nathens, 2008 .

Inflammation and the host response to injury, a large-scale collaborative project: Patient-oriented research core-standard operating procedures for clinical care. IV. Guidelines for transfusion in the trauma patient.

J. Minei, A. Nathens, E. Moore, 2006, The Journal of trauma.

Operative Management of Thoracic Gunshot Wounds: More Aggressive Treatment Has Been Required over Time

J. Richardson, B. Harbrecht, Matthew V. Benns, 2019, The American surgeon.

Article Commentary: Glucose Control and Its Implications for the General Surgeon

B. Harbrecht, Maya Leggett, 2009, The American surgeon.

Nonoperative Management of Blunt Splenic Trauma in the Elderly: Does Age Play a Role?

B. Harbrecht, M. Zenati, G. Watson, 2007, The American surgeon.

Effect of prostoglandins in arginase I expression

B. Harbrecht, J. Ochoa, V. Bansal, 2003 .

JNK signaling involved in the effects of cyclic AMP on IL-1beta plus IFNgamma-induced inducible nitric oxide synthase expression in hepatocytes.

B. Harbrecht, Baochun Zhang, Michele Perpetua, 2004, Cellular signalling.

Activation of a Cyclic Amp-Guanine Exchange Factor in Hepatocytes Decreases Nitric Oxide Synthase Expression

J. Lakshmanan, B. Harbrecht, Baochun Zhang, 2013, Shock.

Inflammation and the Host Response to Injury, a large-scale collaborative project: Patient-Oriented Research Core--standard operating procedures for clinical care. I. Guidelines for mechanical ventilation of the trauma patient.

S. Lowry, J. Minei, A. Nathens, 2005, The Journal of trauma.

Emerging Concepts in Critical Care Nutrition and the Provision of Enteral Nutrition Support

S. McClave, B. Harbrecht, G. Franklin, 2015, Current Surgery Reports.

Lactate as a mediator of prehospital plasma mortality reduction in hemorrhagic shock

F. Guyette, J. Sperry, B. Harbrecht, 2021, The journal of trauma and acute care surgery.

Hepatocyte Injury by Activated Neutrophils In Vitro Is Mediated by Proteases

T. Billiar, B. Harbrecht, J. Stadler, 1993, Annals of surgery.

A Nitric Oxide Scavenger Protects Against Pulmonary Inflammation Following Hemorrhagic Shock

D. Tweardy, A. Ungeheuer, T. Billiar, 2002, Shock.

Effect of Plasma Resuscitation with Adjunctive Peritoneal Resuscitation on Hepatic Blood Flow and End-Organ Damage after Hemorrhagic Shock.

B. Harbrecht, Jason W. Smith, P. Matheson, 2022, Journal of the American College of Surgeons.

Increased interactive format for Morbidity & Mortality conference improves educational value and enhances confidence.

A. Peitzman, T. Billiar, B. Harbrecht, 2007, Journal of surgical education.

Moped Crashes are Just as Dangerous as Motorcycle Crashes

B. Harbrecht, Matthew V. Benns, J. Weaver, 2018, The American surgeon.

A network-based analysis of systemic inflammation in humans

John D. Storey, Charles K. Cooper, G. Casella, 2005, Nature.

Limitations of the Infectious Disease Society of America/Society for Hospital Epidemiologists of America 2017 Update of Guidelines for the Treatment of Clostridium Difficile Colitis.

B. Harbrecht, 2019, Diseases of the colon and rectum.

Blunt splenic injury in adults: Multi-institutional Study of the Eastern Association for the Surgery of Trauma.

B L Enderson, A. Peitzman, S. Fakhry, 2000, The Journal of trauma.

Contribution of age and gender to outcome of blunt splenic injury in adults: multicenter study of the eastern association for the surgery of trauma.

A. Peitzman, S. Fakhry, M. Pasquale, 2001, The Journal of trauma.

Injury to the spleen.

A. Peitzman, D. Potoka, H. Ford, 2001, Current problems in surgery.

Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients.

Mehmet Toner, Palaniappan Sethu, Aman Russom, 2008, Clinical chemistry.

Early supplemental parenteral nutrition is associated with increased infectious complications in critically ill trauma patients.

R. Tompkins, G. O’Keefe, E. Moore, 2008, Journal of the American College of Surgeons.

Closed Midshaft Femur Fractures: Are They Only for Trauma Centers?

A. Malkani, C. Roberts, B. Harbrecht, 2011, The American surgeon.

Management Differences for Pediatric Solid Organ Injuries in a Rural State

J. Richardson, B. Harbrecht, G. Franklin, 2009, The American surgeon.

Lipidomic signatures align with inflammatory patterns and outcomes in critical illness

Upendra K. Kar, F. Guyette, Y. Vodovotz, 2022, Nature communications.

American Association for the Surgery of Trauma Organ Injury Scale (OIS): Past, present, and future

T. Esposito, B. Harbrecht, S. Shafi, 2013, Journal of Trauma and Acute Care Surgery.

Randomized Controlled Trial Evaluating the Efficacy of Peritoneal Resuscitation in the Management of Trauma Patients Undergoing Damage Control Surgery.

J. Richardson, B. Harbrecht, G. Franklin, 2017, Journal of the American College of Surgeons.

Glutathione regulates nitric oxide synthase in cultured hepatocytes.

T. Billiar, B. Harbrecht, R. Simmons, 1997, Annals of surgery.

Tender coconut water suppresses hepatic inflammation by activating AKT and JNK signaling pathways in an in vitro model of sepsis.

C. Klinge, J. Lakshmanan, B. Harbrecht, 2020, Journal of functional foods.

Tumor Necrosis Factor Alpha Inhibits Hepatocyte Mitochondrial Respiration and Induces Release of Cytoplasmic Enzymes

T. Billiar, B. Harbrecht, R. Simmons, 1993 .

Resolving the nitric oxide paradox in acute tissue damage.

T. Billiar, B. Harbrecht, 1997, Gastroenterology.

Necrotizing Soft Tissue Infections: A Review.

B. Harbrecht, Nicholas A. Nash, 2016, Surgical infections.

Firearm Injuries in Women at an Urban Trauma Center

B. Harbrecht, Matthew V. Benns, Nicholas A. Nash, 2017 .

Comparison of longitudinal leukocyte gene expression after burn injury or trauma-hemorrhage in mice.

R. Gamelli, W. Xiao, I. Chaudry, 2008, Physiological genomics.

Essential Role of Induced Nitric Oxide in the Initiation of the Inflammatory Response after Hemorrhagic Shock

A. Peitzman, D. Tweardy, T. Billiar, 1998, The Journal of experimental medicine.

American College of Surgeons and Surgical Infection Society: Surgical Site Infection Guidelines, 2016 Update.

K. Itani, C. Ko, J. Minei, 2017, Journal of the American College of Surgeons.

Hepatic resection in the management of complex injury to the liver.

A. Peitzman, J. Puyana, B. Harbrecht, 2008, The Journal of trauma.

Early VATS for blunt chest trauma: a management technique underutilized by acute care surgeons.

B. Harbrecht, G. Franklin, Jason W Smith, 2011, The Journal of trauma.

Applying the Antecedent, Behavior, Consequence Taxonomy to Unintentional Firearm Injury in a Civilian Population as Determined by a Collaborative Hospital and Law Enforcement Database

B. Harbrecht, Matthew V. Benns, Nicholas A. Nash, 2021, Journal of the American College of Surgeons.

INHIBITION OF NITRIC OXIDE SYNTHESIS DURING SEVERE SHOCK BUT NOT AFTER RESUSCITATION INCREASES HEPATIC INJURY AND NEUTROPHIL ACCUMULATION IN HEMORRHAGED RATS

Simon C Watkins, A. Peitzman, T. Billiar, 1995, Shock.

Plasma resuscitation improves and restores intestinal microcirculatory physiology following haemorrhagic shock

B. Harbrecht, William B. Risinger, Logan Bond, 2023, Vox sanguinis.

Acute appendicitis--not just for the young.

B. Harbrecht, G. Franklin, Frank B. Miller, 2011, American journal of surgery.

Insulin inhibits hepatocyte iNOS expression induced by cytokines by an Akt-dependent mechanism.

B. Harbrecht, Jason W. Smith, Baochun Zhang, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Necrotizing Soft Tissue Infections: A Review.

B. Harbrecht, G. HarbrechtBrian, A. NashNick, 2016, Surgical infections.

Acquisition of Surgical Skills by Hepatobiliary Rotation

J. Richardson, B. Harbrecht, 2015 .

Carbohydrate Provision in the Era of Tight Glucose Control

B. Harbrecht, V. Smith, Christy M. Lawson, 2011, Current gastroenterology reports.

Management of blunt splenic trauma: significant differences between adults and children.

A. Peitzman, M. Gardner, A. Courcoulas, 1997, Surgery.

Intubated Trauma Patients Do Not Require Full Trauma Team Activation when Effectively Triaged.

J. Richardson, B. Harbrecht, Nicholas A. Nash, 2016, Journal of the American College of Surgeons.

Percutaneous endoscopic gastrostomy reduces total hospital costs in head-injured patients.

B. Harbrecht, Anita P. Courcoulas, Robert J. Moraca, 1998, American journal of surgery.