J. Nunès

发表

Dok1 and Dok2 Proteins Regulate Cell Cycle in Hematopoietic Stem and Progenitor Cells

P. Pandolfi, M. Arcangeli, E. Coppin, 2016, The Journal of Immunology.

Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors

Jan Tavernier, Eric Vivier, Laurence Zitvogel, 2011, Nature Medicine.

Dok-4 Is a Novel Negative Regulator of T Cell Activation1

D. Olive, J. Nunès, Geoffrey C. Guittard, 2009, The Journal of Immunology.

The role of p21ras in CD28 signal transduction: triggering of CD28 with antibodies, but not the ligand B7-1, activates p21ras

D. Olive, D. Cantrell, J. Nunès, 1994, The Journal of experimental medicine.

ICOS Ligation Recruits the p50α PI3K Regulatory Subunit to the Immunological Synapse1

D. Olive, V. Lang, F. Carrette, 2008, The Journal of Immunology.

ICOS Ligation Recruits the p50alpha PI3K Regulatory Subunit to the Immunological Synapse

D. Olive, V. Lang, F. Carrette, 2020 .

CD28 deletion improves obesity-induced liver steatosis but increases adiposity in mice

R. Burcelin, J. Nunès, M. Poggi, 2015, International Journal of Obesity.

Control of CD8 T cell proliferation and terminal differentiation by active STAT5 and CDKN2A/CDKN2B

J. Ghysdael, J. Nunès, R. Roncagalli, 2015, Immunology.

Crippling of CD3-ζ ITAMs Does Not Impair T Cell Receptor Signaling

A. Trautmann, B. Malissen, J. Nunès, 1999 .

Anti-T11.1 and -T11.2 monoclonal antibodies play a different role in CD2-mediated signal transduction.

D. Olive, J. Salamero, J. Nunès, 1993, Human immunology.

Dissociation between early and late events in T cell activation mediated through CD28 surface molecule.

D. Olive, J. Nunès, C. Mawas, 1991, Molecular immunology.

Cholera toxin inhibits the increase in cytoplasmic free calcium induced via the CD2 pathway of human T‐lymphocyte activation

D. Olive, J. Nunès, Marc Lopez, 1989, Journal of cellular biochemistry.

T Cells on Engineered Substrates: The Impact of TCR Clustering Is Enhanced by LFA-1 Engagement

J. Nunès, K. Sengupta, L. Limozin, 2018, Front. Immunol..

Dok 1 and Dok 2 proteins regulate natural killer cell development and function

P. Pandolfi, D. Olive, J. Nunès, 2014 .

Dok1 and Dok2 proteins regulate natural killer cell development and function

P. Pandolfi, D. Olive, S. Jonjić, 2014, The EMBO journal.

Analysis of immunoreceptor tyrosine‐based activation motif (ITAM) binding to ZAP‐70 by surface plasmon resonance

Bernard Malissen, B. Malissen, J. Nunès, 1997, European journal of immunology.

CD47-SIRPα Controls ADCC Killing of Primary T Cells by PMN Through a Combination of Trogocytosis and NADPH Oxidase Activation

D. Olive, J. Nunès, F. Gondois-Rey, 2022, bioRxiv.

Homology Domain Interface Independently of Its Pleckstrin Tec Kinase Migrates to the T Cell-APC Olive

D. Olive, D. Isnardon, G. Bismuth, 2004 .

Analysis of Signaling Events by Dynamic Phosphoflow Cytometry

J. Nunès, Guylène Firaguay, 2009, Science Signaling.

CD28 costimulation promotes an antitumor CD8+ T cell response in myeloid antigen-presenting cell niches

D. Olive, J. Nunès, 2021, Cellular & Molecular Immunology.

Transmembrane signaling via both CD3 and CD2 human T cell surface molecules involves protein kinase-C translocation

D. Olive, J. Nunès, Marc Lopez, 1989, La Ricerca in clinica e in laboratorio.

Cutting Edge: Dok-1 and Dok-2 Adaptor Molecules Are Regulated by Phosphatidylinositol 5-Phosphate Production in T Cells1

D. Olive, J. Nunès, B. Payrastre, 2009, The Journal of Immunology.

Author manuscript, published in "European Journal of Immunology 2011;41(12):3443-54" DOI: 10.1002/eji.201141404 Differential role for CD277 as co-regulator of the immune signal in T and NK cells

B. Chetaille, D. Olive, J. Nunès, 2011 .

PD-L2 is expressed on activated human T cells and regulates their function.

D. Olive, J. Nunès, S. Pastor, 2011, Molecular immunology.

Binding of phosphatidyl-inositol-3-OH kinase to CD28 is required for T-cell signalling

D. Olive, R. Rottapel, J. Nunès, 1994, Nature.

Development of an enhanced B-specific lentiviral vector expressing BTK: a tool for gene therapy of XLA

J. Nunès, C. Chabannon, C. Tonnelle, 2008, Gene Therapy.

CD28 signal transduction pathways. A comparison of B7-1 and B7-2 regulation of the map kinases: ERK2 and Jun kinases.

J. Woodgett, D. Olive, D. Cantrell, 1996, Molecular immunology.

The Loss of PTEN Allows TCR (cid:1)(cid:2) Lineage Thymocytes to Bypass IL-7 and Pre-TCR–mediated Signaling

Thijs J. Hagenbeek, J. Trapman, J. Nunès, 2004 .

CISH Expression Is Associated with Metastasis-Free Interval in Triple-Negative Breast Cancer and Refines the Prognostic Value of PDL1 Expression

F. Bertucci, D. Birnbaum, P. Finetti, 2022, Cancers.

[Unleashing NK cell signaling to improve cancer immunotherapy].

J. Nunès, Geoffrey C. Guittard, S. Pastor, 2020, Medecine sciences : M/S.

HCV glycoprotein E2 is a novel BDCA-2 ligand and acts as an inhibitor of IFN production by plasmacytoid dendritic cells.

D. Olive, V. Soumelis, J. Nunès, 2012, Blood.

HCV glycoprotein E 2 is a novel BDCA-2 ligand and acts as an inhibitor of IFN production by plasmacytoid dendritic cells

D. Olive, V. Soumelis, J. Nunès, 2012 .

in T Cells Phosphatidylinositol 5-Phosphate Production Molecules Are Regulated by Cutting Edge: Dok-1 and Dok-2 Adaptor

D. Olive, J. Nunès, B. Payrastre, 2009 .

DOK4 and DOK5: new dok-related genes expressed in human T cells

D. Olive, P. Pontarotti, J. Nunès, 2003, Genes and Immunity.

The MEK1/2-ERK Pathway Inhibits Type I IFN Production in Plasmacytoid Dendritic Cells

D. Olive, J. Nunès, P. Dubreuil, 2018, Front. Immunol..

A critical regulatory role for the cytoplasmic domain of CD28 in ligand binding in naive T cells.

J. Nunès, Xiao-jun Guo, Hai-Tao He, 2020, Science bulletin.

In the absence of its cytosolic domain, the CD28 molecule still contributes to T cell activation

D. Olive, J. Mege, J. Nunès, 2015, Cellular and Molecular Life Sciences.

Role for the CD28 Molecule in the Control of Coxiella burnetii Infection

D. Olive, D. Raoult, H. Lepidi, 2006, Infection and Immunity.

Signal Transduction by CD28 Costimulatory Receptor on T Cells

D. Olive, D. Cantrell, J. Nunès, 1996, The Journal of Biological Chemistry.

Tec kinases: a family with multiple roles in immunity.

D. Olive, J. Nunès, Y. Collette, 2000, Immunity.

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

D. Olive, R. Rottapel, J. Nunès, 1994, Nature.

T cell activation via the CD2 molecule is associated with protein kinase C translocation from the cytosol to the plasma membrane

D. Olive, J. Nunès, A. Pierrès, 1989, European journal of immunology.

Evidence for a positive role of PtdIns5P in T‐cell signal transduction pathways

J. Nunès, B. Payrastre, Geoffrey C. Guittard, 2010, FEBS letters.

The Loss of PTEN Allows TCR αβ Lineage Thymocytes to Bypass IL-7 and Pre-TCR–mediated Signaling

Thijs J. Hagenbeek, J. Trapman, J. Nunès, 2004, The Journal of experimental medicine.

Travel informations on the Tec kinases during lymphocyte activation.

J. Nunès, F. Garçon, 2006, Advances in experimental medicine and biology.

Role of Tec kinase in nuclear factor of activated T cells signaling.

D. Olive, J. Nunès, R. Castellano, 2000, International immunology.

CD28 mAbs with distinct binding properties differ in their ability to induce T cell activation: analysis of early and late activation events.

D. Olive, J. Nunès, C. Mawas, 1993, International immunology.

Dual Role of the Tyrosine Kinase Syk in Regulation of Toll-Like Receptor Signaling in Plasmacytoid Dendritic Cells

D. Olive, J. Nunès, S. Létard, 2016, PloS one.

Tec Kinase Migrates to the T Cell-APC Interface Independently of Its Pleckstrin Homology Domain1

D. Olive, D. Isnardon, G. Bismuth, 2004, The Journal of Immunology.

The SH3 domain of Tec kinase is essential for its targeting to activated CD28 costimulatory molecule

D. Olive, J. Nunès, A. Gérard, 2004, European journal of immunology.

[The role of co-inhibitory signals driven by CTLA-4 in immune system].

L. Xerri, D. Olive, J. Nunès, 2011, Medecine sciences : M/S.

Functional expression of human CD28 in murine T cell hybridomas.

D. Olive, J. Nunès, C. Mawas, 1994, Molecular immunology.

Monoclonal antibodies against LFA-1 or its ligand ICAM-1 accelerate CD2 (T11.1 + T11.2)-mediated T cell proliferation.

D. Olive, J. Nunès, A. Pierrès, 1989, Cellular immunology.

Triggering CD 28 molecules synergize with CD 2 (T11.1 and T11,2)‐mediated T cell activation

D. Olive, J. Nunès, A. Pierrès, 1988, European journal of immunology.

ADAPted secretion of cytokines in NK cells

J. Nunès, É. Vivier, S. Ugolini, 2013, Nature Immunology.

Anti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expressing tumors

D. Olive, B. Malissen, J. Nunès, 2022, bioRxiv.

For Peer Review 1 PD-L 1 and PD-L 2 differ in their molecular mechanisms of interaction with PD-1

D. Olive, J. Nunès, L. Gauthier, 2018 .

A pharmacological strategy to recapitulate exercise-induced antitumoral immunity.

A. Carrier, J. Nunès, A. Rebillard, 2022, Trends in pharmacological sciences.

TCR and CD28 Concomitant Stimulation Elicits a Distinctive Calcium Response in Naive T Cells

J. Nunès, Y. Hamon, C. Billaudeau, 2018, Front. Immunol..

IFN-alpha skews monocyte differentiation into Toll-like receptor 7-expressing dendritic cells with potent functional activities.

D. Olive, M. Mohty, D. Isnardon, 2003, Journal of immunology.

CD277 an Immune Regulator of T Cell Function and Tumor Cell Recognition

D. Olive, M. Bonneville, P. Pontarotti, 2011 .

Constitutive AKT activation in follicular lymphoma

R. Bouabdallah, L. Xerri, D. Olive, 2014, BMC Cancer.

NK Cell Priming From Endogenous Homeostatic Signals Is Modulated by CIS

Melissa J. Davis, S. Hediyeh-zadeh, F. Souza-Fonseca-Guimaraes, 2020, Frontiers in Immunology.

DOK1 and DOK2 regulate CD8+ T cell signaling and memory formation without affecting tumor cell killing

D. Olive, J. Nunès, Y. Yamanashi, 2021, bioRxiv.

Targeting CISH enhances natural cytotoxicity receptor signaling and reduces NK cell exhaustion to improve solid tumor immunity

D. Olive, N. Huntington, J. Nunès, 2021, Journal for ImmunoTherapy of Cancer.

CISH targeting in NK cells activates natural cytotoxicity receptor signaling and reduce cell exhaustion to unsilence primary anti-tumor response

N. Huntington, J. Nunès, É. Vivier, 2022 .

PD-L1 and PD-L2 differ in their molecular mechanisms of interaction with PD-1.

D. Olive, J. Nunès, L. Gauthier, 2010, International immunology.

Natural Killer Cell Signaling Pathways

Eric Vivier, J. Nunès, F. Vély, 2004, Science.

An Emerging Role for PI5P in T Cell Biology

J. Nunès, Geoffrey C. Guittard, G. Guittard, 2013, Front. Immunol..

Functional interaction of RasGAP-binding proteins Dok-1 and Dok-2 with the Tec protein tyrosine kinase

D. Olive, J. Nunès, Y. Collette, 2004, Oncogene.

TET2 regulates immune tolerance in chronically activated mast cells

B. Göttgens, O. Bernard, G. Bidaut, 2022, JCI insight.

Natural Killer Defective Maturation Is Associated with Adverse Clinical Outcome in Patients with Acute Myeloid Leukemia

S. Granjeaud, D. Olive, A. Toubert, 2017, Front. Immunol..

Hepatitis C Virus Fails To Activate NF-κB Signaling in Plasmacytoid Dendritic Cells

D. Olive, J. Nunès, I. Hirsch, 2011, Journal of Virology.

A non-conserved amino acid variant regulates differential signalling between human and mouse CD28

I. Screpanti, Martina Kunkl, L. Tuosto, 2018, Nature Communications.

Vitamin D Controls Tumor Growth and CD8+ T Cell Infiltration in Breast Cancer

D. Olive, J. Nunès, C. Fauriat, 2019, Front. Immunol..

Chronic IL-15 Stimulation and Impaired mTOR Signaling and Metabolism in Natural Killer Cells During Acute Myeloid Leukemia

D. Olive, Y. Kerdiles, G. Bidaut, 2021, Frontiers in Immunology.

Fit αβ T-cell receptor suppresses leukemogenesis of Pten-deficient thymocytes

B. Nadel, B. Malissen, J. Nunès, 2018, Haematologica.

High-dimensional mass cytometry analysis of NK cell alterations in AML identifies a subgroup with adverse clinical outcome

S. Granjeaud, D. Olive, D. Blaise, 2021, Proceedings of the National Academy of Sciences.

High-dimensional mass cytometry analysis of NK cell alterations in Acute Myeloid Leukemia identifies a subgroup with adverse clinical outcome

S. Granjeaud, D. Olive, D. Blaise, 2020, medRxiv.

Modulation of T Cell Activation in Obesity.

J. Nunès, M. Poggi, M. Alessi, 2017, Antioxidants & redox signaling.

Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation.

Hai-Tao He, Hervé Rigneault, Yannick Hamon, 2008, Nature chemical biology.

Novel CD28-Responsive Enhancer Activated by CREB/ATF and AP-1 Families in the Human Interleukin-2 Receptor α-Chain Locus

D. Olive, S. Spicuglia, P. Lécine, 2001, Molecular and Cellular Biology.

Hepatitis C virus fails to activate NF-kappaB signaling in plasmacytoid dendritic cells

D. Olive, J. Nunès, I. Hirsch, 2012, Retrovirology.

Crippling of CD3-zeta ITAMs does not impair T cell receptor signaling.

A. Trautmann, B. Malissen, J. Nunès, 1999, Immunity.

Negative intracellular regulators of T-cell receptor (TCR) signaling as potential antitumor immunotherapy targets

J. Nunès, Geoffrey C. Guittard, V. Laletin, 2023, Journal for ImmunoTherapy of Cancer.

Quantification of Immune Variables from Liquid Biopsy in Breast Cancer Patients Links Vδ2+ γδ T Cell Alterations with Lymph Node Invasion

F. Bertucci, S. Granjeaud, D. Olive, 2021, Cancers.

A non-conserved amino acid variant regulates differential signalling between human and mouse CD28

I. Screpanti, Martina Kunkl, L. Tuosto, 2018, Nature Communications.

Hepatitis C virus fails to activate NF-kappaB signaling in plasmacytoid dendritic cells

D. Olive, J. Nunès, I. Hirsch, 2012, Retrovirology.

Flow cytometric analysis of intracellular phosphoproteins in human monocytes

E. Coppin, J. Nunès, C. Favre, 2017, Cytometry. Part B, Clinical cytometry.

High-throughput mass cytometry staining for deep phenotyping of human natural killer cells

D. Olive, J. Nunès, N. Vey, 2022, STAR protocols.

Analysis of cellular signaling events by flow cytometry

E. Coppin, J. Nunès, Guylène Firaguay, 2012 .

Differential role for CD 277 as co-regulator of the immune signal in T and NK cells

B. Chetaille, D. Olive, J. Nunès, 2011 .

Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation.

H. Rigneault, D. Marguet, D. Olive, 2008, Nature Chemical Biology.

Evolutionary and expression analyses reveal a pattern of ancient duplications and functional specializations in the diversification of the Downstream of Kinase (DOK) genes

S. Granjeaud, P. Pontarotti, J. Nunès, 2018, Developmental and comparative immunology.

Anti-HVEM mAb therapy improves antitumoral immunity both in vitro and in vivo, in a novel transgenic mouse model expressing human HVEM and BTLA molecules challenged with HVEM expressing tumors

D. Olive, B. Malissen, J. Nunès, 2023, Journal for ImmunoTherapy of Cancer.

The Loss of PTEN Allows TCR αβ Lineage Thymocytes to Bypass IL-7 and Pre-TCR–mediated Signaling

Thijs J. Hagenbeek, J. Trapman, J. Nunès, 2004, The Journal of experimental medicine.

In the absence of its cytosolic domain, the CD28 molecule still contributes to T cell activation

D. Olive, J. Mege, J. Nunès, 2015, Cellular and Molecular Life Sciences.