K. Kline

发表

α-TEA cooperates with MEK or mTOR inhibitors to induce apoptosis via targeting IRS/PI3K pathways

R. Tiwary, W. Yu, B. G. Sanders, 2010, British Journal of Cancer.

RRR‐α‐tocopheryl succinate induction of prolonged activation of c‐jun amino‐terminal kinase and c‐jun during induction of apoptosis in human MDA‐MB‐435 breast cancer cells

P. Brown, M. Birrer, B. G. Sanders, 1998 .

Activation of extracellular signal-regulated kinase and c-Jun-NH(2)-terminal kinase but not p38 mitogen-activated protein kinases is required for RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells.

F. Hantash, B. G. Sanders, K. Kline, 2001, Cancer research.

Primary research

R. Tiwary, B. G. Sanders, K. Kline, 1999 .

RRR-alpha-tocopheryl succinate induces MDA-MB-435 and MCF-7 human breast cancer cells to undergo differentiation.

W. Yu, B. G. Sanders, K. Kline, 2001, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

RRR-- Tocopheryl Succinate Induces MDA-MB-435 and MCF-7 Human Breast Cancer Cells to Undergo Differentiation 1

B. G. Sanders, K. Kline, Weiping Yu, 2001 .

RRR‐α‐tocopheryl succinate enhances TGF‐β1, ‐β2, and ‐β3 and TGF‐βR‐II expression by human MDA‐MB‐435 breast cancer cells

B. G. Sanders, K. Kline, Weiping Yu, 1996 .

Vitamin E Succinate: Mechanisms of Action as Tumor Cell Growth Inhibitor

B. G. Sanders, K. Kline, Weiping Yu, 1995 .

Elimination of ALDH+ breast tumor initiating cells by docosahexanoic acid and/or gamma tocotrienol through SHP‐1 inhibition of Stat3 signaling

B. G. Sanders, K. Kline, Weiping Yu, 2016, Molecular carcinogenesis.

Vitamin E and cancer.

Karla A. Lawson, B. G. Sanders, K. Kline, 2007, Vitamins and hormones.

Vitamin E Succinate Induces Apoptosis in Human Prostate Cancer Cells: Role for Fas in Vitamin E Succinate-Triggered Apoptosis

W. Yu, B. G. Sanders, K. Kline, 2000, Nutrition and cancer.

Liposomal or Nanoparticle α-TEA Reduced 66cl-4 Murine Mammary Cancer Burden and Metastasis

B. G. Sanders, K. Kline, Linjiao Jia, 2007 .

Vitamin E succinate induction of HL-60 cell adhesion: a role for fibronectin and a 72-kDa fibronectin-binding molecule.

B. G. Sanders, K. Kline, J. Turley, 1995, Nutrition and cancer.

RRR-α-Tocopheryl Succinate Modulation of Human Promyelocytic Leukemia (HL-60) Cell Proliferation and Differentiation

B. G. Sanders, K. Kline, J. Turley, 1992 .

Novel vitamin E analogue decreases syngeneic mouse mammary tumor burden and reduces lung metastasis.

Karla A. Lawson, Luzhe Sun, C. Conti, 2003, Molecular cancer therapeutics.

RRR-alpha-tocopheryl succinate inhibits proliferation and enhances secretion of transforming growth factor-beta (TGF-beta) by human breast cancer cells.

B. G. Sanders, K. Kline, M. Simmons‐Menchaca, 1993, Nutrition and cancer.

Vitamin E Family of Compounds and Cancer Prevention

R. Tiwary, B. G. Sanders, K. Kline, 2013 .

Synthesis and screening of novel vitamin E derivatives for anticancer functions.

B. G. Sanders, K. Kline, Weiping Yu, 2012, European journal of medicinal chemistry.

Distinct roles of different forms of vitamin E in DHA-induced apoptosis in triple-negative breast cancer cells.

R. Tiwary, B. G. Sanders, K. Kline, 2012, Molecular nutrition & food research.

Involvement of de novo ceramide synthesis in gamma-tocopherol and gamma-tocotrienol-induced apoptosis in human breast cancer cells.

B. G. Sanders, K. Kline, Weiping Yu, 2012, Molecular nutrition & food research.

Anticancer actions of natural and synthetic vitamin E forms: RRR- α -tocopherol blocks the anticancer actions of γ -tocopherol

B. G. Sanders, K. Kline, Weiping Yu, 2011 .

Tocotrienols induce apoptosis in breast cancer cell lines via an endoplasmic reticulum stress-dependent increase in extrinsic death receptor signaling

B. G. Sanders, K. Kline, Sook-Kyung Park, 2010, Breast Cancer Research and Treatment.

RRR‐α‐Tocopheryl succinate inhibits proliferation and enhances secretion of transforming growth factor‐β (TGF‐β) by human breast cancer cells

B. G. Sanders, K. Kline, M. Simmons‐Menchaca, 1993 .

Involvement of activator protein‐1 (AP‐1) in induction of apoptosis by vitamin E succinate in human breast cancer cells

P. Brown, M. Birrer, B. G. Sanders, 1997, Molecular carcinogenesis.

Pro-apoptotic Mechanisms of Action of a Novel Vitamin E Analog (α-TEA) and a Naturally Occurring Form of Vitamin E (δ-Tocotrienol) in MDA-MB-435 Human Breast Cancer Cells

Rachel J Parsons, B. G. Sanders, K. Kline, 2004 .

Evidence for role of transforming growth factor-beta in RRR-alpha-tocopheryl succinate-induced apoptosis of human MDA-MB-435 breast cancer cells.

W. Yu, B. G. Sanders, K. Kline, 1997, Nutrition and cancer.

Vitamin E and Breast Cancer Prevention: Current Status and Future Potential

Karla A. Lawson, B. G. Sanders, K. Kline, 2004, Journal of Mammary Gland Biology and Neoplasia.

Novel vitamin E analogue and 9-nitro-camptothecin administered as liposome aerosols decrease syngeneic mouse mammary tumor burden and inhibit metastasis

Karla A. Lawson, Luzhe Sun, B. G. Sanders, 2004, Cancer Chemotherapy and Pharmacology.

Vitamin E succinate (VES) induces Fas sensitivity in human breast cancer cells: role for Mr 43,000 Fas in VES-triggered apoptosis.

W. Yu, B. G. Sanders, K. Kline, 1999, Cancer research.

RRR-alpha-tocopheryl succinate inhibits EL4 thymic lymphoma cell growth by inducing apoptosis and DNA synthesis arrest.

W. Yu, B. G. Sanders, K. Kline, 1997, Nutrition and cancer.

RRR‐α‐tocopheryl succinate induces apoptosis in avian retrovirus‐transformed lymphoid cells

B. G. Sanders, K. Kline, M. Qian, 1996 .

RRR-alpha-tocopheryl succinate inhibits DNA synthesis and enhances the production and secretion of biologically active transforming growth factor-beta by avian retrovirus-transformed lymphoid cells.

W. Yu, B. G. Sanders, K. Kline, 1995, Nutrition and cancer.

Effects of RRR-α-tocopheryl succinate on IL-1 and PGE2 production by macrophages

B. G. Sanders, K. Kline, E. Romach, 1993 .

RRR-alpha-tocopheryl succinate modulation of human promyelocytic leukemia (HL-60) cell proliferation and differentiation.

B. G. Sanders, K. Kline, J. Turley, 1992, Nutrition and cancer.

Activation of Extracellular Signal-regulated Kinase and c-Jun-NH 2 -terminal Kinase but not p38 Mitogen-activated Protein Kinases Is Required for RRR- (cid:1) -Tocopheryl Succinate-induced Apoptosis of Human Breast Cancer Cells

F. Hantash, B. G. Sanders, K. Kline, 2001 .

Succinate-induced Apoptosis of Human Breast Cancer Cells-Tocopheryl α Protein Kinases Is Required for RRR-- terminal Kinase but not p 38 Mitogen-activated 2 c-Jun-NH Activation of Extracellular Signal-regulated Kinase and Updated

F. Hantash, B. G. Sanders, K. Kline, 2001 .

The Anticancer Effects of Vitamin E Derivative alpha-TEA in Human Hematological Malignancies APPROVED BY SUPERVISING COMMITTEE:

B. G. Sanders, K. Kline, Weiping Yu, 2010 .

Chicken transferrin receptor expression during erythroid differentiation and by retrovirus transformed cells.

B. G. Sanders, K. Kline, T. Morgan, 1989, Developmental and comparative immunology.

Chemical and immunological characterization of developmentally expressed chicken erythroid surface membrane antigens.

J. Allison, B. G. Sanders, K. Kline, 1982, Developmental biology.

Eliminating drug resistant breast cancer stem-like cells with combination of simvastatin and gamma-tocotrienol.

B. G. Sanders, K. Kline, Weiping Yu, 2013, Cancer letters.

Alpha Tocopheryl Succinate Amelioration of Retrovirus-Induced Inhibition of Macrophage Chemotaxis

B. G. Sanders, K. Kline, E. Romach, 1993 .

Simvastatin inhibition of mevalonate pathway induces apoptosis in human breast cancer cells via activation of JNK/CHOP/DR5 signaling pathway.

B. G. Sanders, K. Kline, Weiping Yu, 2013, Cancer letters.

RRR‐α‐Tocopheryl succinate inhibition of lectin‐induced T cell proliferation

B. G. Sanders, K. Kline, 1993 .

Immune abnormalities in avian erythroblastosis virus-infected chickens.

B. G. Sanders, K. Kline, A. Rao, 1990, Cancer research.

Vitamin E Effects on Retrovirus‐Induced Immune Dysfunctions a

B. G. Sanders, K. Kline, A. Rao, 1990 .

RRR-alpha-tocopheryl succinate enhances T cell mitogen-induced proliferation and reduces suppressor activity in spleen cells derived from AEV-infected chickens.

B. G. Sanders, K. Kline, 1991, Nutrition and cancer.

RRR-alpha-tocopheryl succinate induced interleukin-2 production by avian splenic T lymphocytes and murine EL-4 thymic lymphoma cells.

B. G. Sanders, K. Kline, S. Kidao, 1993, Biotechnology therapeutics.

Modulation of murine EL-4 thymic lymphoma cell proliferation and cytokine production by vitamin E succinate.

W. Yu, B. G. Sanders, K. Kline, 1996, Nutrition and cancer.

Growth-inhibitory effects of vitamin E succinate on retrovirus-transformed tumor cells in vitro.

B. G. Sanders, K. Kline, G. S. Cochran, 1990, Nutrition and cancer.

Vitamin E Modulation of Retrovirus‐Induced Immune Dysfunctions and Tumor‐Cell Proliferation a

B. G. Sanders, K. Kline, A. Rao, 1989 .

Modulation of immune suppression and enhanced tumorigenesis in retrovirus tumor challenged chickens treated with vitamin E.

B. G. Sanders, K. Kline, 1989, In vivo.

Suppression of Con A mitogen-induced proliferation of normal spleen cells by macrophages from chickens with hereditary muscular dystrophy.

B. G. Sanders, K. Kline, 1984, Journal of immunology.

Demonstration of a cellular defect in the thymus of hereditary muscular dystrophic chickens.

B. G. Sanders, K. Kline, 1982, Thymus.

Chicken lymphocyte FCR binding properties of IgG from avian and non-avian species.

B. G. Sanders, K. Kline, R. Dietert, 1980, Developmental and comparative immunology.

RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells involves Bax translocation to mitochondria.

B. G. Sanders, K. Kline, Weiping Yu, 2003, Cancer research.

RRR-alpha-tocopheryl succinate inhibits the proliferation of human prostatic tumor cells with defective cell cycle/differentiation pathways.

B. G. Sanders, K. Kline, K. Israel, 1995, Nutrition and cancer.

N-(4-hydroxyphenyl)retinamide activation of transforming growth factor-beta and induction of apoptosis in human breast cancer cells.

B. Herbert, B. G. Sanders, K. Kline, 1999, Nutrition and cancer.

Downregulation of Epidermal Growth Factor Receptor Expression Contributes to α-TEA's Proapoptotic Effects in Human Ovarian Cancer Cell Lines

B. G. Sanders, K. Kline, Weiping Yu, 2010, Journal of oncology.

Role of extracellular signal–regulated kinase pathway in RRR‐α‐tocopheryl succinate–induced differentiation of human MDA‐MB‐435 breast cancer cells

P. Brown, B. G. Sanders, K. Kline, 2002, Molecular carcinogenesis.

Vitamin E: mechanisms of action as tumor cell growth inhibitors.

B. G. Sanders, K. Kline, Weiping Yu, 2001, The Journal of nutrition.

α-TEA cooperates with chemotherapeutic agents to induce apoptosis of p53 mutant, triple-negative human breast cancer cells via activating p73

R. Tiwary, B. G. Sanders, K. Kline, 2011, Breast Cancer Research.

RRR-gamma-tocopherol induces human breast cancer cells to undergo apoptosis via death receptor 5 (DR5)-mediated apoptotic signaling.

R. Tiwary, B. G. Sanders, K. Kline, 2008, Cancer letters.

α-TEA inhibits survival and enhances death pathways in cisplatin sensitive and resistant human ovarian cancer cells

B. G. Sanders, K. Kline, Weiping Yu, 2006, Apoptosis.

Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols.

W. Yu, B. G. Sanders, K. Kline, 1999, Nutrition and cancer.

Involvement of JNK/p73/NOXA in vitamin E analog‐induced apoptosis of human breast cancer cells

V. Iyer, Zhanzhi Hu, B. G. Sanders, 2008, Molecular carcinogenesis.

Vitamin E and breast cancer.

B. G. Sanders, K. Kline, Weiping Yu, 2004, The Journal of nutrition.

RRR-α--Tocopheryl Succinate Induction of DNA Synthesis Arrest of Human MDA-MB-435 Cells Involves TGF-β--Independent Activation of p21Waf1/Cip1

B. G. Sanders, K. Kline, Weiping Yu, 2002 .

α‐TEA induces apoptosis of human breast cancer cells via activation of TRAIL/DR5 death receptor pathway

R. Tiwary, B. G. Sanders, K. Kline, 2010, Molecular carcinogenesis.

In vitro and in vivo evaluation of anticancer actions of natural and synthetic vitamin E forms.

Karla A. Lawson, Luzhe Sun, B. G. Sanders, 2008, Molecular nutrition & food research.

In vivo and in vitro studies of anticancer actions of α‐TEA for human prostate cancer cells

B. G. Sanders, K. Kline, Weiping Yu, 2008, The Prostate.

International Research Conference on Food , Nutrition , and Cancer Vitamin E and Breast Cancer 1

B. G. Sanders, K. Kline, Weiping Yu, 2004 .

Hematopoietic differentiation cell surface antigen switching in the bone marrow of different aged chickens.

B. G. Sanders, K. Kline, C. H. Nelson, 1984, Differentiation; research in biological diversity.

Role of Endoplasmic Reticulum Stress in α-TEA Mediated TRAIL/DR5 Death Receptor Dependent Apoptosis

R. Tiwary, B. G. Sanders, K. Kline, 2010, PloS one.

Targeting cholesterol-rich microdomains to circumvent tamoxifen-resistant breast cancer

Richa Tiwary, R. Tiwary, B. G. Sanders, 2011, Breast Cancer Research.

Anticancer actions of natural and synthetic vitamin E forms: RRR-alpha-tocopherol blocks the anticancer actions of gamma-tocopherol.

B. G. Sanders, K. Kline, Weiping Yu, 2009, Molecular nutrition & food research.

Critical roles for JNK, c‐Jun, and Fas/FasL‐Signaling in vitamin E analog‐induced apoptosis in human prostate cancer cells

B. G. Sanders, K. Kline, Weiping Yu, 2008, The Prostate.

RRR-alpha-tocopheryl succinate inhibition of lectin-induced T cell proliferation.

B. G. Sanders, K. Kline, 1993, Nutrition and cancer.

α-TEA Plus Cisplatin Reduces Human Cisplatin-Resistant Ovarian Cancer Cell Tumor Burden and Metastasis

Karla A. Lawson, Luzhe Sun, B. G. Sanders, 2004, Experimental biology and medicine.

Chicken fetal antigens: role as cell surface receptors for Sindbis virus hemagglutinin.

B. G. Sanders, K. Kline, R. Garry, 1980, Virology.

Differential Response of Human Ovarian Cancer Cells to Induction of Apoptosis by Vitamin E Succinate and Vitamin E Analogue, α-TEA

Karla A. Lawson, B. G. Sanders, K. Kline, 2004, Cancer Research.

Abstract 190: Targeting ceramide and endoplasmic reticulum-stress in vitamin E induced apoptosis in human breast cancer cells

B. G. Sanders, K. Kline, Weiping Yu, 2011 .

Monoclonal antibody to chicken fetal antigens on normal erythroid cells and hematopoietic-lymphoid tumor cell lines.

J. Allison, B. G. Sanders, K. Kline, 1982, Cancer research.

Characterization of two distinct disulfide-linked B-G molecules in the chicken.

B. G. Sanders, K. Kline, L. Bacon, 1988, The Journal of heredity.

Vitamin E Analog α-TEA and Celecoxib Alone and Together Reduce Human MDA-MB-435-FL-GFP Breast Cancer Burden and Metastasis in Nude Mice

Karla A. Lawson, Luzhe Sun, B. G. Sanders, 2004, Breast Cancer Research and Treatment.

RRR-alpha-tocopheryl succinate induction of DNA synthesis arrest of human MDA-MB-435 cells involves TGF-beta-independent activation of p21Waf1/Cip1.

B. G. Sanders, K. Kline, Weiping Yu, 2002, Nutrition and cancer.

c-Jun involvement in vitamin E succinate induced apoptosis of reticuloendotheliosis virus transformed avian lymphoid cells

B. G. Sanders, K. Kline, Weiping Yu, 1997, Oncogene.

Vitamin E Analog α -TEA, Methylseleninic Acid, and Trans-Resveratrol in Combination Synergistically Inhibit Human Breast Cancer Cell Growth

B. G. Sanders, K. Kline, Weiping Yu, 2008, Nutrition and cancer.

Stable Expression of a New Chimeric Fluorescent Reporter in the Human Malaria Parasite Plasmodium falciparum

K. Haldar, K. Kline, T. Akompong, 2000, Infection and Immunity.

Comparison of Vitamin E Derivatives α-TEA and VES in Reduction of Mouse Mammary Tumor Burden and Metastasis

Karla A. Lawson, Luzhe Sun, B. G. Sanders, 2004, Experimental biology and medicine.

Nutrition, immunology and cancer: an overview.

B. G. Sanders, K. Kline, 1995, Advances in experimental medicine and biology.

Developmental profile of chicken splenic lymphocyte responsiveness to Con A and PHA and studies on chicken splenic and bone marrow cells capable of inhibiting mitogen-stimulated blastogenic responses of adult splenic lymphocytes.

B. G. Sanders, K. Kline, 1980, Journal of Immunology.

Vitamin E analog, alpha-tocopherol ether-linked acetic acid analog, alone and in combination with celecoxib, reduces multiplicity of ultraviolet-induced skin cancers in mice

S. Fischer, B. G. Sanders, K. Kline, 2008, Anti-cancer drugs.

alpha-TEA inhibits survival and enhances death pathways in cisplatin sensitive and resistant human ovarian cancer cells.

B. G. Sanders, K. Kline, Weiping Yu, 2006, Apoptosis : an international journal on programmed cell death.

Pro-apoptotic mechanisms of action of a novel vitamin E analog (alpha-TEA) and a naturally occurring form of vitamin E (delta-tocotrienol) in MDA-MB-435 human breast cancer cells.

Rachel J Parsons, B. G. Sanders, K. Kline, 2004, Nutrition and cancer.

Immunochemical characterization of differentiation and age-related cell surface antigens expressed by chicken erythrocytes.

J. Allison, B. G. Sanders, K. Kline, 1984, Cancer research.

Aerosol Delivery of Liposomal Formulated Paclitaxel and Vitamin E Analog Reduces Murine Mammary Tumor Burden and Metastases

B. G. Sanders, K. Kline, Weiping Yu, 2009, Experimental biology and medicine.

In vivo and in vitro studies of anticancer actions of α‐TEA for human prostate cancer cells

B. G. Sanders, K. Kline, Weiping Yu, 2008, The Prostate.

Molecular characterization of fetal antigens on red blood cells of chickens, Japanese quail, and quail-chicken hybrids

B. G. Sanders, K. Kline, Rodney R. Dietert, 1984, Biochemical Genetics.

Utilization of a differential hemoglobin elution procedure as a rapid assay for identification of embryonic and adult chicken red blood cells.

B. G. Sanders, K. Kline, 1977, Comparative biochemistry and physiology. B, Comparative biochemistry.