D. Vasilcanu

发表

Aberrant intracellular IGF-1R beta-subunit makes receptor knockout cells (IGF1R-/-) susceptible to oncogenic transformation.

O. Larsson, M. Axelson, L. Girnita, 2009, Experimental cell research.

Expression and Growth Dependency of the Insulin-Like Growth Factor I Receptor in Craniopharyngioma Cells: A Novel Therapeutic Approach

O. Larsson, M. Axelson, L. Girnita, 2005, Clinical Cancer Research.

Insulin-Like Growth Factor Type-I Receptor-Dependent Phosphorylation of Extracellular Signal-Regulated Kinase 1/2 but not Akt (Protein Kinase B) Can Be Induced by Picropodophyllin

M. Axelson, L. Girnita, D. Vasilcanu, 2008, Molecular Pharmacology.

IGF-1R tyrosine kinase expression and dependency in clones of IGF-1R knockout cells (R-).

O. Larsson, M. Axelson, L. Girnita, 2006, Biochemical and biophysical research communications.

The insulin-like growth factor-1 receptor inhibitor PPP produces only very limited resistance in tumor cells exposed to long-term selection

O. Larsson, C. Larsson, W. Lui, 2006, Oncogene.

Over-accumulation of nuclear IGF-1 receptor in tumor cells requires elevated expression of the receptor and the SUMO-conjugating enzyme Ubc9.

O. Larsson, D. Vasilcanu, Yingbo Lin, 2011, Biochemical and biophysical research communications.

The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway

O. Larsson, M. Axelson, L. Girnita, 2004, Oncogene.

Picropodophyllin induces downregulation of the insulin-like growth factor 1 receptor: potential mechanistic involvement of Mdm2 and β-arrestin1

O. Larsson, M. Axelson, L. Girnita, 2008, Oncogene.

IGF-1R inhibition : A tool for functional studies of insulin-like growth factor family in malignant cells

D. Vasilcanu, 2006 .

From the Department of Oncology and Pathology, Division of Cellular and Molecular Tumor Pathology, Cancer Center Karolinska Karolinska Institutet, Stockholm, Sweden IGF-1R INHIBITION: A TOOL FOR FUNCTIONAL STUDIES OF INSULIN- LIKE GROWTH FACTORS FAMILY IN MALIGNANT CELLS

D. Vasilcanu, 2006 .

Molecular Characterization of Acquired Tolerance of Tumor Cells to Picropodophyllin (PPP)

O. Larsson, C. Larsson, W. Lui, 2011, PloS one.

Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin‐like growth factor‐1 receptor

O. Larsson, M. Axelson, L. Girnita, 2008, Acta ophthalmologica.

Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor.

O. Larsson, M. Axelson, L. Girnita, 2008, Investigative ophthalmology & visual science.

β-Arrestin and Mdm2 Mediate IGF-1 Receptor-stimulated ERK Activation and Cell Cycle Progression*

Robert J. Lefkowitz, O. Larsson, R. Lefkowitz, 2007, Journal of Biological Chemistry.

Beta-arrestin and Mdm2 mediate IGF-1 receptor-stimulated ERK activation and cell cycle progression.

O. Larsson, R. Lefkowitz, L. Girnita, 2007, The Journal of biological chemistry.

Insulin-like growth factor type-I receptor (IGF-1R) dependent phosphorylation of ERK1/2 but not Akt (PKB) can be induced by picropodophyllin

M. Axelson, L. Girnita, D. Vasilcanu, 2007 .

Over-accumulation of nuclear IGF-1 receptor in tumor cells requires elevated expression of the receptor and the SUMO-conjugating enzyme Ubc9.

O. Larsson, D. Vasilcanu, Yingbo Lin, 2011, Biochemical and biophysical research communications.

Vasilcanu D, Girnita A, Girnita L, Vasilcanu R, Axelson M, Larsson O.. The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway. Oncogene 23: 7854-7862

O. Larsson, M. Axelson, L. Girnita, 2004 .

Correction: The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway

O. Larsson, M. Axelson, L. Girnita, 2022, Oncogene.

Picropodophyllin induces downregulation of the insulin-like growth factor 1 receptor: potential mechanistic involvement of Mdm2 and beta-arrestin1.

M. Axelson, L. Girnita, D. Vasilcanu, 2008, Oncogene.

Correction: Picropodophyllin induces downregulation of the insulin-like growth factor 1 receptor: potential mechanistic involvement of Mdm2 and β-arrestin1

O. Larsson, M. Axelson, L. Girnita, 2022, Oncogene.