Yan Chen

Jing He, Yan Chen, Hong-li Liu, 2006, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.

Betulinic acid inhibits autophagic flux and induces apoptosis in human multiple myeloma cells in vitro

Jing He, Yan Chen, G. Cui, 2012, Acta Pharmacologica Sinica.

pH-responsive core-shell nanogels induce in situ antigen production for cancer treatment

Chen Chen, Yan Chen, Jun Luo, 2021 .

Triptolide-induced apoptosis by inactivating nuclear factor-kappa B apoptotic pathway in multiple myeloma in vitro

Rui Li, Yan Chen, R. Zeng, 2011, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.

Apoptosis of HL-60 human leukemia cells induced by Asiatic acid through modulation of B-cell lymphoma 2 family proteins and the mitogen-activated protein kinase signaling pathway.

Yan Chen, Lu Wen, T. Lv, 2015, Molecular medicine reports.

Effect of Gambogic acid on the regulation of hERG channel in K562 cells in vitro

Yan Chen, Qing Wu, G. Cui, 2009, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.

Oridonin induces NPM mutant protein translocation and apoptosis in NPM1c+ acute myeloid leukemia cells in vitro

Jing He, Yan Chen, G. Cui, 2014, Acta Pharmacologica Sinica.

MiR-375 delivered by lipid-coated doxorubicin-calcium carbonate nanoparticles overcomes chemoresistance in hepatocellular carcinoma.

Yan Chen, Minsi Li, Robert J. Lee, 2017, Nanomedicine : nanotechnology, biology, and medicine.

Effects of triptolide on RIZ1 expression, proliferation, and apoptosis in multiple myeloma U266 cells

Yan Chen, R. Zeng, Fei Zhao, 2010, Acta Pharmacologica Sinica.

Clinical Characteristics of 5 COVID-19 Cases With Non-respiratory Symptoms as the First Manifestation in Children

Yan Chen, Wenbin Li, Xiao-fang Cai, 2020, Frontiers in Pediatrics.

Anti-cancer effects of deguelin on human leukemia K562 and K562/ADM cells In Vitro

Jing He, Yan Chen, Hong-li Liu, 2007, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.

Autophagy counteracts apoptosis in human multiple myeloma cells exposed to oridonin in vitro via regulating intracellular ROS and SIRT1

Yan Chen, G. Cui, R. Zeng, 2011, Acta Pharmacologica Sinica.

Selenium-Doped Calcium Carbonate Nanoparticles Loaded with Cisplatin Enhance Efficiency and Reduce Side Effects.

Yan Chen, Minsi Li, Robert J. Lee, 2019, International journal of pharmaceutics.

Mangiferin increases Nrf2 protein stability by inhibiting its ubiquitination and degradation in human HL60 myeloid leukemia cells.

Yan Chen, Jun Fang, Jie Zhao, 2014, International journal of molecular medicine.

Mangiferin increases Nrf 2 protein stability by inhibiting its ubiquitination and degradation in human HL 60 myeloid leukemia cells

Yan Chen, L. Shanshan, Jun Fang, 2022 .

Antitumor effect of interferon-on U937 human acute leukemia cells in vitro and its molecular mechanism

Yan Chen, G. Cui, Chun Zhang, 2007, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.

Deguelin regulates nuclear pore complex proteins Nup98 and Nup88 in U937 cells in vitro

Jing He, Yan Chen, G. Cui, 2005, Acta Pharmacologica Sinica.

Curcumin, a potent anti-tumor reagent, is a novel histone deacetylase inhibitor regulating B-NHL cell line Raji proliferation

Yan Chen, G. Cui, Jian-feng Zhou, 2005, Acta Pharmacologica Sinica.

One-pot synthesis of a microporous organosilica-coated cisplatin nanoplatform for HIF-1-targeted combination cancer therapy

Chen Chen, Yan Chen, Minsi Li, 2020, Theranostics.

Involvement of SRC-3 in deguelin-induced apoptosis in Jurkat cells

Yan Chen, Rui-Yun Li, Wen Shu, 2009, International journal of hematology.

Prevention of infection in immunosuppressive patients with autoimmune nephrosis by using an immunostimulating bacterial lysate Broncho-vaxom

Yan Chen, Ying Yao, H. Luan, 2012, Human vaccines & immunotherapeutics.

Deguelin inhibits expression of IκBα protein in Raji and U937 cells

Yan Chen, G. Cui, Wei-Hua Chen, 2006, Acta Pharmacologica Sinica.

Human fused NKG2D–IL-15 protein controls xenografted human gastric cancer through the recruitment and activation of NK cells

Yan Chen, Bei Chen, Yanbing Ding, 2015, Cellular and Molecular Immunology.

A Solid Lipid Coated Calcium Peroxide Nanocarrier Enables Combined Cancer Chemo/Chemodynamic Therapy with O2/H2O2 Self-Sufficiency.

Yan Chen, Robert J. Lee, Jun Luo, 2020, Acta biomaterialia.

Effects of triptolide on histone acetylation and HDAC8 expression in multiple myeloma in vitro

Rui Li, Yan Chen, Fei Zhao, 2010 .

Inhibitory effect of triptolide on lymph node metastasis in patients with non-Hodgkin lymphoma by regulating SDF-1/CXCR4 axis in vitro

Yan Chen, G. Cui, Qiu-ling Wu, 2006, Acta Pharmacologica Sinica.

Quick staining technique for myeloperoxidase using potassium iodide and oxidized pyronine B.

Yan Chen, Hao Zhou, Fei Zhao, 2014, Acta histochemica.

Adult systemic Epstein-Barr virus-positive T-cell lymphoproliferative disease: A case report.

Yan Chen, Youping Wang, Xinyue Liu, 2015, Experimental and therapeutic medicine.

Effects of betulinic acid on proliferation and apoptosis in Jurkat cells and its in vitro mechanism

Jing He, Yan Chen, Qiuling Wu, 2008, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.

Trichostatin a regulates hGCN5 expression and cell cycle on Daudi cells in vitro

Yan Chen, G. Cui, Gang Wu, 2006, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.

Mangiferin activates the Nrf2-ARE pathway and reduces etoposide-induced DNA damage in human umbilical cord mononuclear blood cells

Yan Chen, Jun Fang, Jie Zhao, 2015, Pharmaceutical biology.

Cyclic reactions-mediated self-supply of H2O2 and O2 for cooperative chemodynamic/starvation cancer therapy.

Chen Chen, Yan Chen, Yongkang Gai, 2021, Biomaterials.

Down-regulation of tissue factor by siRNA increased doxorubicin-induced apoptosis in human neuroblastoma

Mu-xiang Zhou, Yan Chen, Jun Fang, 2008, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.

Nuclear Translocation of Argonaute 2 in Cytokine-Induced Senescence

O. Bischof, Yan Chen, T. Wieder, 2018, Cellular Physiology and Biochemistry.

Enhancement of cisplatin efficacy by lipid-CaO2 nanocarrier-mediated comprehensive modulation of the tumor microenvironment.

Chen Chen, Yan Chen, Minsi Li, 2019, Biomaterials science.

Biocompatible co-loading vehicles for delivering both nanoplatin cores and siRNA to treat hepatocellular carcinoma.

Yan Chen, Minsi Li, Robert J. Lee, 2019, International journal of pharmaceutics.

Effects of curcumin on proliferation of NB4 cells and acetylation of histone H3 and P53

Xia Li, Yan Chen, Qing Wu, 2004 .

Somatic cell and sperm cell cytogenetics in a patient with t(14; 21).

Yan Chen, C. Xiong, Yuan-Fei Liu, 2006, Yi chuan xue bao = Acta genetica Sinica.

Triptolide inhibits cell growth and induces G0- G1 arrest by regulating P21wap1/cip1 and P27 kip1 in human multiple myeloma RPMI-8226 cells

Rui Li, Yan Chen, Fei Zhao, 2010 .

Antiproliferartion effects of curcumin on the STAT5 signaling pathway in K562 cells

Yan Chen, Hong-li Liu, Weihong Chen, 2005 .

Effects of gambogic acid on regulation of steroid receptor coactivator-3 in lung adenocarcinoma A549 cells

Yan Chen, Fei Zhao, Lu Wen, 2009 .

Nano Encapsulated Curcumin: And Its Potential for Biomedical Applications

Yan Chen, Robert J. Lee, Guangya Xiang, 2020, International journal of nanomedicine.

Infants Born to Mothers With a New Coronavirus (COVID-19)

Yan Chen, Lingkong Zeng, Yin Zhao, 2020, Frontiers in Pediatrics.

Hierarchically constructed selenium-doped bone-mimetic nanoparticles promote ROS-mediated autophagy and apoptosis for bone tumor inhibition.

Shengmin Zhang, Yan Chen, Jianglin Wang, 2020, Biomaterials.

Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on hepatocellular carcinoma cells for enhanced apoptosis and reduced hepatotoxicity

Asifullah Khan, Yan Chen, S. Raza, 2019, International journal of nanomedicine.

A smart O2-generating nanocarrier optimizes drug transportation comprehensively for chemotherapy improving

Chen Chen, Yan Chen, Jun Luo, 2021, Acta pharmaceutica Sinica. B.

Co‐delivery of doxorubicin and imatinib by pH sensitive cleavable PEGylated nanoliposomes with folate‐mediated targeting to overcome multidrug resistance

Shasha Zhang, Yan Chen, Minsi Li, 2018, International journal of pharmaceutics.

Prognostic Value of Ionized Calcium Levels in Neonatal Sepsis

Yan Chen, Yalan Liu, Yannan Chai, 2020, Annals of Nutrition and Metabolism.

Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway

Yan Chen, Xiaozhong Zhou, Huang Fang, 2020, Experimental biology and medicine.

Expression of connexin 32 and connexin 43 in acute myeloid leukemia and their roles in proliferation.

Yan Chen, G. Cui, S. Yi, 2012, Oncology Letters.

[CML cell line K562 cell apoptosis induced by mangiferin].

Yan Chen, L. Xia, Jun Luo, 2004, Zhongguo shi yan xue ye xue za zhi.

Mangiferin activates Nrf2-antioxidant response element signaling without reducing the sensitivity to etoposide of human myeloid leukemia cells in vitro

Yan Chen, Li-jing Yang, Jun Fang, 2013, Acta Pharmacologica Sinica.

Cisplatin and curcumin co‐loaded nano‐liposomes for the treatment of hepatocellular carcinoma

Yan Chen, Xiang Ma, Guangya Xiang, 2018, International journal of pharmaceutics.

Platinum complexes of curcumin delivered by dual-responsive polymeric nanoparticles improve chemotherapeutic efficacy based on the enhanced anti-metastasis activity and reduce side effects

Xiang Ma, Ruicong Yan, Muhammad Sarfraz, 2019, Acta pharmaceutica Sinica. B.

Enhancing anti-tumor efficiency in hepatocellular carcinoma through the autophagy inhibition by miR-375/sorafenib in lipid-coated calcium carbonate nanoparticles.

Yan Chen, Minsi Li, Robert J. Lee, 2018, Acta biomaterialia.

Down-regulation of HSP70 sensitizes gastric epithelial cells to apoptosis and growth retardation triggered by H. pylori

Wei-Li Liu, Yan Chen, J. Si, 2011, BMC gastroenterology.

Matrix stiffness regulates epithelial-mesenchymal transition via cytoskeletal remodeling and MRTF-A translocation in osteosarcoma cells.

Huan Wang, Yan Chen, Huang Fang, 2019, Journal of the mechanical behavior of biomedical materials.

Deguelin, a selective silencer of the NPM1 mutant, potentiates apoptosis and induces differentiation in AML cells carrying the NPM1 mutation

Jing He, Yan Chen, G. Cui, 2015, Annals of Hematology.

Molecular mechanisms underlying the time-dependent autophagy and apoptosis induced by nutrient depletion in multiple myeloma: a pilot study

Yan Chen, G. Cui, Lu Wen, 2012, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.

Curcumin, both histone deacetylase and p300/CBP-specific inhibitor, represses the activity of nuclear factor kappa B and Notch 1 in Raji cells.

Yan Chen, Qing Wu, G. Cui, 2007, Basic & clinical pharmacology & toxicology.

Long Noncoding RNA LINC01134 Promotes Hepatocellular Carcinoma Metastasis via Activating AKT1S1 and NF-κB Signaling

Yan Chen, Chao Wang, Lei Zhang, 2020, Frontiers in Cell and Developmental Biology.

Gambogic acid induces G0/G1 arrest and apoptosis involving inhibition of SRC-3 and inactivation of Akt pathway in K562 leukemia cells.

Yan Chen, Fei Zhao, Lu Wen, 2009, Toxicology.

Wortmannin inhibits K562 lukemic cells by regulating PI3k/Akt channel in vitro

Triptolide alters histone H3K9 and H3K27 methylation state and induces G0/G1 arrest and caspase-dependent apoptosis in multiple myeloma in vitro.

Yan Chen, Fei Zhao, Lu Wen, 2010, Toxicology.

Role of triptolide in cell proliferation, cell cycle arrest, apoptosis and histone methylation in multiple myeloma U266 cells.

Yan Chen, R. Zeng, Fei Zhao, 2010, European journal of pharmacology.

Involvement of regulations of nucleophosmin and nucleoporins in gambogic acid-induced apoptosis in Jurkat cells.

Yan Chen, Qing Wu, G. Cui, 2008, Basic & clinical pharmacology & toxicology.

Deguelin represses both the expression of nucleophosmin and some nucleoporins: Nup88 and Nup214 in Jurkat cells.

Yan Chen, Qing Wu, G. Cui, 2008, Biological & pharmaceutical bulletin.

Mangiferin Promotes Bregs Level, Activates Nrf2 Antioxidant Signaling, and Inhibits Proinflammatory Cytokine Expression in Murine Splenic Mononuclear Cells In Vitro

Yan Chen, Ping Chen, K. Sun, 2021, Current Medical Science.

Abstract 4477: MIK665/S64315, a novel Mcl-1 inhibitor, in combination with Bcl-2 inhibitors exhibits strong synergistic antitumor activity in a range of hematologic malignancies

F. Colland, Youzhen Wang, Ensar Halilovic, 2019, Experimental and Molecular Therapeutics.

Thioredoxin-1 Protects Bone Marrow-Derived Mesenchymal Stromal Cells from Hyperoxia-Induced Injury In Vitro

Yan Chen, Lei Zhang, Lingkong Zeng, 2018, Oxidative medicine and cellular longevity.

Novel URAT1 mutations caused acute renal failure after exercise in two Chinese families with renal hypouricemia.

Yan Chen, Yongman Lv, H. Ding, 2013, Gene.

Effects of gambogic acid on the regulation of nucleoporin Nup88 in U937 cells

Jing He, Yan Chen, G. Cui, 2007, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.

Steroid receptor coactivator-3 is a pivotal target of gambogic acid in B-cell Non-Hodgkin lymphoma and an inducer of histone H3 deacetylation.

Yan Chen, G. Cui, S. Yi, 2016, European journal of pharmacology.

Anticancer activities of trichostatin A on malignant lymphoid cells

Yan Chen, Chunyan Sun, Xinyue Liu, 2006, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban.

HIF-1 dependent reversal of cisplatin resistance via anti-oxidative nano selenium for effective cancer therapy

Yan Chen, Minsi Li, Jun Luo, 2020 .

Sudden severe thrombocytopenia in a patient in the recovery stage of COVID-19

Yan Chen, Hao Zhou, Bohan Yang, 2020, The Lancet Haematology.

Ulinastatin-Gold Nanoparticles Reduce Sepsis-Induced Cardiomyocyte Apoptosis Through NF-κB Pathway Inactivation

Yan Chen, Lihua Xiao, 2020 .

[The role of stromal cell derived factor-1/CXCR4 biological axis in tumor metastasis of non-Hodgkin lymphoma].

Yan Chen, G. Cui, Qiu-ling Wu, 2007, Zhonghua yi xue za zhi.

[Effects of triptolide and TNF-alpha on the expression of VEGF in Raji cells and on angiogenesis in ECV304 cells].

Yan Chen, G. Cui, Wei-Hua Chen, 2006, Zhongguo shi yan xue ye xue za zhi.

Successful recovery of a patient with multiple myeloma from severe coronavirus disease 2019 (COVID-19) pneumonia during the first chemotherapy cycle: A case report.

Yan Chen, Hao Zhou, Haiping Song, 2021, Experimental and therapeutic medicine.