Hongpeng Liu

发表

Bioinformatics-based discovery and characterization of an AKT-selective inhibitor 9-chloro-2-methylellipticinium acetate (CMEP) in breast cancer cells.

Shaomeng Wang, Xueliang Fang, Dajun Yang, 2007, Cancer letters.

Structural basis for a non-phosphorus-containing cyclic peptide binding to Grb2-SH2 domain with high affinity.

Dajun Yang, P. Roller, P. Li, 2003, Biochemical and biophysical research communications.

Gossypol induces apoptosis in human PC-3 prostate cancer cells by modulating caspase-dependent and caspase-independent cell death pathways.

Q. Li, Manchao Zhang, Hongpeng Liu, 2007, Life sciences.

A novel Bcl-2 small molecule inhibitor 4-(3-methoxy-phenylsulfannyl)-7-nitro-benzofurazan-3-oxide (MNB)-induced apoptosis in leukemia cells

Shaomeng Wang, R. Mohammad, Renxiao Wang, 2007, Annals of Hematology.

Synthesis of the First α‐Fluoro‐Phosphotyrosyl Mimetic

Dajun Yang, T. Burke, Manchao Zhang, 2004 .

DIFFERENTIAL GROWTH INHIBITION AND INDUCTION OF APOPTOSIS BY GOSSYPOL BETWEEN HCT116 AND HCT116/BAX−/– COLORECTAL CANCER CELLS

Q. Li, Manchao Zhang, Hongpeng Liu, 2007, Clinical and experimental pharmacology & physiology.

Synthesis of a phosphotyrosyl analogue having χ1, χ2 and φ angles constrained to values observed for an SH2 domain-bound phosphotyrosyl residue

C. George, Dajun Yang, T. Burke, 2003 .

Synergistic anti-leukemic activity of imatinib in combination with a small molecule Grb2 SH2 domain binding antagonist

C. Croce, Manchao Zhang, Hongpeng Liu, 2013, Leukemia.

Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells.

Dajun Yang, Manchao Zhang, Shaomeng Wang, 2003, Biochemical pharmacology.

Synthesis of α,α-disubstituted 4-phosphonophenylalanine analogues as conformationally-constrained phosphotyrosyl mimetics

J. Deschamps, Dajun Yang, Manchao Zhang, 2004 .

Concise and enantioselective synthesis of Fmoc-Pmp(But)2-OH and design of potent Pmp-containing Grb2-SH2 domain antagonists.

Dajun Yang, P. Roller, Manchao Zhang, 2003, Organic letters.

Blockade of AKT activation in prostate cancer cells with a small molecule inhibitor, 9-chloro-2-methylellipticinium acetate (CMEP).

Shaomeng Wang, Xueliang Fang, Dajun Yang, 2007, Biochemical pharmacology.

Potent Grb2-SH2 domain antagonists not relying on phosphotyrosine mimics.

Dajun Yang, Megan L Peach, Manchao Zhang, 2003, Bioorganic & medicinal chemistry letters.

Structure-based design of thioether-bridged cyclic phosphopeptides binding to Grb2-SH2 domain.

Dajun Yang, P. Roller, Manchao Zhang, 2003, Bioorganic & medicinal chemistry letters.

Utilization of a beta-aminophosphotyrosyl mimetic in the design and synthesis of macrocyclic Grb2 SH2 domain-binding peptides.

Dajun Yang, T. Burke, Manchao Zhang, 2003, Journal of medicinal chemistry.

Synthesis of a C-terminally biotinylated macrocyclic peptide mimetic exhibiting high Grb2 SH2 domain-binding affinity.

Dajun Yang, Robert J Fisher, Zhen-Dan Shi, 2005, Bioorganic & medicinal chemistry.

A novel macrocyclic tetrapeptide mimetic that exhibits low-picomolar Grb2 SH2 domain-binding affinity.

Dajun Yang, Robert J Fisher, Zhen-Dan Shi, 2003, Biochemical and biophysical research communications.