J. Ware

发表

Megakaryocyte proliferation and ploidy regulated by the cytoplasmic tail of glycoprotein Ibalpha.

T. Kanaji, S. Russell, J. Cunningham, 2004, Blood.

Factor IXAlabama: a point mutation in a clotting protein results in hemophilia B.

J. Ware, L. Davis, R. McGraw, 1987, Blood.

Genetic defect responsible for the dysfunctional protein: factor IXLong Beach.

J. Ware, L. Davis, D. Stafford, 1988, Blood.

MAPPING OF 6 MONOCLONAL ANTIBODIES TO HUMAN FACTOR IX

S. W. Lin, Shu-Wha Lin, R. Ljung, 1987, Thrombosis and Haemostasis.

Dimerization of glycoprotein Ibα is not sufficient to induce platelet clearance

S. Russell, J. Ware, X. Liang, 2016, Journal of thrombosis and haemostasis : JTH.

Visualizing the von Willebrand factor/glycoprotein Ib-IX axis with a platelet-type von Willebrand disease mutation.

S. Russell, J. Ware, Junling Liu, 2009, Blood.

von Willebrand factor mutation enhancing interaction with platelets in patients with normal multimeric structure.

J. Ware, Z. Ruggeri, R. Schneppenheim, 1993, The Journal of clinical investigation.

Defective dimerization of von Willebrand factor subunits due to a Cys-> Arg mutation in type IID von Willebrand disease.

J. Ware, Z. Ruggeri, R. Schneppenheim, 1996, Proceedings of the National Academy of Sciences of the United States of America.

The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion.

T. Kanaji, S. Russell, J. Ware, 2003, Blood.

Factor IXAlabama: a point mutation in a clotting protein results in hemophilia B.

R. McGraw, J. Ware, H. Roberts, 1987 .

Distinct Pathogenesis of Pancreatic Cancer Microvesicle–Associated Venous Thrombosis Identifies New Antithrombotic Targets In Vivo

B. Engelmann, N. Mackman, J. Ware, 2018, Arteriosclerosis, thrombosis, and vascular biology.

Deduced amino acid sequence of mouse blood-coagulation factor IX.

J. Ware, D. Stafford, S. Wu, 1990, Gene.

Structure and Function of von Willebrand Factor

J. Ware, Z. Ruggeri, 1992, Thrombosis and Haemostasis.

Defective Association of the Platelet Glycoprotein Ib–IX Complex with the Glycosphingolipid-Enriched Membrane Domain Inhibits Murine Thrombus and Atheroma Formation

C. Ballantyne, J. Ware, A. Reddy, 2016, The Journal of Immunology.

Thrombocytopathy leading to impaired in vivo haemostasis and thrombosis in platelet type von Willebrand disease

J. Ware, M. Othman, Harmanpreet Kaur, 2016, Thrombosis and Haemostasis.

Role for Platelet Glycoprotein Ib-IX and Effects of its Inhibition in Endotoxemia-Induced Thrombosis, Thrombocytopenia, and Mortality

Xiaoping Du, J. Ware, Z. Wang, 2013, Arteriosclerosis, thrombosis, and vascular biology.

Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor.

J. Ware, S. Berkowitz, Z. Ruggeri, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Lateral Clustering of Platelet GP Ib-IX Complexes Leads to Up-regulation of the Adhesive Function of Integrin αIIbβ3 *

J. Ware, Z. Ruggeri, S. Shattil, 2002, The Journal of Biological Chemistry.

Distinct antithrombotic consequences of platelet glycoprotein Ibα and VI deficiency in a mouse model of arterial thrombosis

J. Ware, D. Loskutoff, Z. Ruggeri, 2006, Journal of thrombosis and haemostasis : JTH.

Calcium Ion Chelation Preserves Platelet Function During Cold Storage

J. Ware, A. Morris, S. Smyth, 2020, Arteriosclerosis, thrombosis, and vascular biology.

Calcium ion chelation preserves platelet function during cold storage

J. Ware, A. Morris, S. Smyth, 2020, bioRxiv.

GPIbα regulates platelet size by controlling the subcellular localization of filamin.

T. Kanaji, J. Ware, P. Newman, 2012, Blood.

Absence of GPIbalpha is responsible for aberrant membrane development during megakaryocyte maturation: ultrastructural study using a transgenic model.

P. Nurden, B. Nieswandt, J. Ware, 2002, Experimental hematology.

Murine models of glycoprotein Ib-IX

J. Ware, 2022, Platelets.

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

A. Walch, K. Preissner, M. Schwaiger, 2012, The Journal of experimental medicine.

Platelet function beyond hemostasis and thrombosis

J. Ware, Adam Corken, Reshma Khetpal, 2013, Current opinion in hematology.

Biological role of prolyl 3-hydroxylation in type IV collagen

R. Fässler, M. Moser, J. Ware, 2013, Proceedings of the National Academy of Sciences.

Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer

Caroline L. Wilson, Patrick M. Helbling, F. Tacke, 2019, Nature Medicine.

Nucleotide sequence of a cDNA for a member of the human 90-kDa heat-shock protein family.

R. Bertina, J. Ware, P. Modrich, 1987, Gene.

Platelets: balancing the septic triad.

J. Ware, S. Post, 2014, Blood.

Dysfunctional platelet membrane receptors: from humans to mice

J. Ware, 2004, Thrombosis and Haemostasis.

Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role

S. Diamond, T. Smithgall, J. Ware, 2009, Proceedings of the National Academy of Sciences of the United States of America.

The Septin CDCrel-1 Is Dispensable for Normal Development and Neurotransmitter Release

J. Ware, Zhengping Jia, W. Trimble, 2002, Molecular and Cellular Biology.

The Modifier of hemostasis (Mh) locus on chromosome 4 controls in vivo hemostasis of Gp6-/- mice.

José A Fernández, T. Wiltshire, M. Cooke, 2008, Blood.

A Sensitive Ristocetin Co-factor Activity Assay with Recombinant Glycoprotein Ibα for the Diagnosis of Patients with Low Von Willebrand Factor Levels

P. Mannucci, J. Ware, A. Federici, 2022 .

A prototypic platelet septin and its participation in secretion

P. Nurden, J. Ware, W. Trimble, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Gamma-Tocotrienol Protects the Intestine from Radiation Potentially by Accelerating Mesenchymal Immune Cell Recovery

A. Basnakian, J. Ware, M. Hauer-Jensen, 2019, Antioxidants.

Prostaglandins produced during class A scavenger receptor‐mediated macrophage adhesion differentially regulate cytokine production

J. Ware, S. Post, T. Kelly, 2015, Journal of leukocyte biology.

Amelioration of the macrothrombocytopenia associated with the murine Bernard-Soulier syndrome.

T. Kanaji, S. Russell, J. Ware, 2002, Blood.

The ribosomal DNA transcription unit of the house cricket,Acheta domesticus

J. Ware, M. D. Cave, Z. Sharp, 1987, Biochemical Genetics.

Molecular cloning of a cDNA encoding canine factor IX.

J. Ware, K. High, H. Watzke, 1989, Blood.

Conformational Changes in the A1 Domain of von Willebrand Factor Modulating the Interaction with Platelet Glycoprotein Ib (*)

J. Ware, S. Miyata, A. Federici, 1996, The Journal of Biological Chemistry.

Platelet Glycoprotein VI Haplotypes and the Presentation of Paediatric Sepsis

J. Ware, P. Prodhan, J. Dent, 2018, Thrombosis and Haemostasis.

Platelets and Inflammatory Disorders of Connective Tissue

J. Ware, S. Post, 2017 .

The Role of Platelet Adhesion Receptor GPIb α Far Exceeds That of Its Main Ligand von Willebrand Factor in Arterial Thrombosis.

D. Wagner, J. Ware, W. Bergmeier, 2006 .

Platelets Participate in Synovitis via Cox-1–Dependent Synthesis of Prostacyclin Independently of Microparticle Generation

J. Ware, K. Jacobs, R. Farndale, 2011, The Journal of Immunology.

Independently of Microparticle Generation Dependent Synthesis of Prostacyclin - Platelets Participate in Synovitis via Cox-1

J. Ware, K. Jacobs, R. Farndale, 2011 .

GPIbα is required for platelet-mediated hepatic thrombopoietin generation.

J. Marshall, J. Freedman, J. Ware, 2018, Blood.

Let's shear a moment, then take it inside.

J. Ware, 2018, Blood.

The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies.

J. Freedman, J. Ware, Conglei Li, 2011, The Journal of clinical investigation.

von Willebrand factor

J. Ware, Z. Ruggeri, 1993, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Thermostable Bst DNA polymerase I lacks a 3'-->5' proofreading exonuclease activity.

H. Kong, J. Ware, H Kong, 1996, Genetic analysis : biomolecular engineering.

Identification of Essential GATA and Ets Binding Motifs within the Promoter of the Platelet Glycoprotein Ibα Gene (*)

J. Ware, Y. Hashimoto, 1995, The Journal of Biological Chemistry.

Thrombocytopenia Impairs Host Defense Against Burkholderia pseudomallei (Melioidosis)

T. van der Poll, N. Day, J. Ware, 2018, The Journal of infectious diseases.

Convulxin binds to native, human glycoprotein Ib alpha.

T. Kanaji, J. Ware, T. Kunicki, 2003, The Journal of biological chemistry.

Generation and rescue of a murine model of platelet dysfunction: the Bernard-Soulier syndrome.

S. Russell, J. Ware, Z. Ruggeri, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer

Caroline L. Wilson, Patrick M. Helbling, F. Tacke, 2019, Nature Network Boston.

Hemostasis vs. homeostasis: Platelets are essential for preserving vascular barrier function in the absence of injury or inflammation

Shuchi Gupta, B. Nieswandt, J. Ware, 2020, Proceedings of the National Academy of Sciences.

Analysis of genes for 5S rRNA from the cricket, Acheta domesticus: two classes of repeating units.

J. Ware, M. D. Cave, H. Beneš, 1985, Gene.

Platelet ITAM signaling is critical for vascular integrity in inflammation.

Agnieszka Cholka, N. Mackman, J. Ware, 2013, The Journal of clinical investigation.

Isolated recombinant domain of von Willebrand factor displaying increased sensitivity to ristocetin

Tomohiro Hayashi, J. Ware, N. Sakuragawa, 1996, American journal of hematology.

Down-regulation of the serotonin transporter in hyperreactive platelets counteracts the pro-thrombotic effect of serotonin.

Preeti Singh, S. Lensing, J. Ware, 2012, Journal of molecular and cellular cardiology.

Genetic defect responsible for the dysfunctional protein: factor IXLong Beach.

J. Ware, L. Davis, D. Stafford, 1988, Blood.

Non‐myeloablative conditioning with busulfan before hematopoietic stem cell transplantation leads to phenotypic correction of murine Bernard‐Soulier syndrome

J. Ware, R. Montgomery, S. Fahs, 2014, Journal of thrombosis and haemostasis : JTH.

Genetic deletion of mouse platelet glycoprotein Ibβ produces a Bernard-Soulier phenotype with increased α-granule size

P. Nurden, S. Fiering, S. Russell, 2004 .

Genetic deletion of mouse platelet glycoprotein Ibbeta produces a Bernard-Soulier phenotype with increased alpha-granule size.

P. Nurden, S. Fiering, S. Russell, 2004, Blood.

Nonsense mutation in the glycoprotein Iba coding sequence associated with Bernard-Soulier syndrome (platelet receptor/thrombosis/bleeding disorder/platelet adhesion/thrombocytopenia)

S. Russell, J. Ware, V. Vicente, 2016 .

Identification of a point mutation in type IIB von Willebrand disease illustrating the regulation of von Willebrand factor affinity for the platelet membrane glycoprotein Ib-IX receptor.

J. Ware, H. Azuma, P. Kyrle, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Localization of a factor VIII-inhibiting antibody epitope to a region between residues 338 and 362 of factor VIII heavy chain.

J. Ware, D. Stafford, J. Toomey, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Platelet glycoprotein Ib alpha supports experimental lung metastasis.

Masahiko Zuka, S. Russell, J. Ware, 2007, Proceedings of the National Academy of Sciences of the United States of America.

Lateral clustering of platelet GP Ib-IX complexes leads to up-regulation of the adhesive function of integrin alpha IIbbeta 3.

J. Ware, Z. Ruggeri, S. Shattil, 2002, The Journal of biological chemistry.

Mapping of monoclonal antibodies to human factor IX

Shu-Wha Lin, J. Ware, A. Thompson, 1989 .

The role of platelet adhesion receptor GPIbα far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis

D. Wagner, J. Ware, W. Bergmeier, 2006, Proceedings of the National Academy of Sciences.

Megakaryocytes compensate for Kit insufficiency in murine arthritis

Y. Iwakura, J. Ware, P. Nigrovic, 2017, The Journal of clinical investigation.

Fragmenting the platelet to reduce metastasis.

J. Ware, 2012, Blood.

Association of platelet function with depression and its treatment with sertraline in patients with chronic kidney disease: analysis of a randomized trial

J. Ware, S. Hedayati, R. Sarode, 2019, BMC Nephrology.

Disulfide bond requirements for assembly of the platelet glycoprotein Ib-binding domain of von Willebrand factor.

T. Hayashi, J. Ware, H. Azuma, 1993, The Journal of biological chemistry.

Platelets Amplify Inflammation in Arthritis via Collagen-Dependent Microparticle Production

Richard W. Farndale, Eric Boilard, Michael E. Weinblatt, 2010, Science.

Cloning of thermostable DNA polymerases from hyperthermophilic marine Archaea with emphasis on Thermococcus sp. 9 degrees N-7 and mutations affecting 3'-5' exonuclease activity.

M. Southworth, F. Perler, H. Kong, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Inhibiting GPIb&agr; Shedding Preserves Post-Transfusion Recovery and Hemostatic Function of Platelets After Prolonged Storage

Renhao Li, J. Ware, C. Josephson, 2016, Arteriosclerosis, thrombosis, and vascular biology.

Point mutation in a leucine-rich repeat of platelet glycoprotein Ib alpha resulting in the Bernard-Soulier syndrome.

S. Russell, J. Ware, M. Murata, 1993, The Journal of clinical investigation.

Cloning of the murine platelet glycoprotein Ibalpha gene highlighting species-specific platelet adhesion.

S. Russell, J. Ware, Z. Ruggeri, 1997, Blood cells, molecules & diseases.

Nonsense mutation in the glycoprotein Ib alpha coding sequence associated with Bernard-Soulier syndrome.

S. Russell, J. Ware, V. Vicente, 1990, Proceedings of the National Academy of Sciences of the United States of America.

An arginine to cysteine amino acid substitution at a critical thrombin cleavage site in a dysfunctional factor VIII molecule.

J. Ware, C. Fulcher, M. Shima, 1989, Blood.

In Vivo Expression of Murine Platelet Glycoprotein Ibα

S. Russell, J. Ware, B. Zieger, 1998 .

In vivo expression of murine platelet glycoprotein Ibalpha.

S. Russell, J. Ware, Y. Hashimoto, 1998, Blood.

Role of Platelets in Chronic Kidney Disease.

J. Ware, J. Arthur, N. Jain, 2021, Journal of the American Society of Nephrology : JASN.

Molecular Analyses of the Platelet Glycoprotein Ib-IX-V Receptor

J. Ware, J. Ware, 1998, Thrombosis and Haemostasis.

Nbeal2 Deficiency Increases Organ Damage but Does Not Affect Host Defense During Gram-Negative Pneumonia-Derived Sepsis

T. van der Poll, J. Ware, A. D. de Vos, 2018, Arteriosclerosis, thrombosis, and vascular biology.

Genetic deletion of mouse platelet glycoprotein Ibproduces

P. Nurden, S. Fiering, S. Russell, 2004 .

- Soulier phenotype with increased produces a β Genetic deletion of mouse platelet glycoprotein Ib

P. Nurden, S. Russell, J. Ware, 2004 .

Correction of murine Bernard-Soulier syndrome by lentivirus-mediated gene therapy.

J. Ware, R. Montgomery, S. Fahs, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

cleavage site in a dysfunctional factor VIII molecule An arginine to cysteine amino acid substitution at a critical thrombin

J. Ware, C. Fulcher, M. Shima, 2011 .

A comparison of washed and volume‐reduced platelets with respect to platelet activation, aggregation, and plasma protein removal

J. Bornhorst, J. Ware, M. Nakagawa, 2011, Transfusion.

Epitope Localization of Anti-Factor VIII Monoclonal Antibodies Determined by Recombinant peptides

J. Ware, D. Stafford, D. Stafford, 1989, Thrombosis and Haemostasis.

Epitope mapping of human factor VIII inhibitor antibodies by site‐directed mutagenesis of a factor VIII polypeptide

J. Ware, C. Fulcher, S. de Graaf, 1992, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Identification of a F.VIII epitope recognized by a human hemophilic inhibitor.

J. Ware, H. Reisner, B. Lubahn, 1989, Blood.

hemophilia B Factor IXAlabama: a point mutation in a clotting protein results in

J. Ware, L. Davis, R. McGraw, 2011 .

The Malmö polymorphism of coagulation factor IX, an immunologic polymorphism due to dimorphism of residue 148 that is in linkage disequilibrium with two other F.IX polymorphisms.

S. W. Lin, D. Lubahn, S. Lord, 1988, American journal of human genetics.

Thrombocytopathy and type 2B von Willebrand disease.

J. Ware, 2013, The Journal of clinical investigation.

Identification of a F.VIII epitope recognized by a human hemophilic inhibitor.

J. Ware, H. Reisner, B. Lubahn, 1989, Blood.

Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease.

J. Ware, J. Arthur, S. Hedayati, 2023, Vascular pharmacology.

Mammalian Septin Function in Hemostasis and Beyond

J. Ware, C. Martínez, 2004, Experimental biology and medicine.

Blocking von Willebrand factor for treatment of cutaneous inflammation.

C. Denis, B. Nieswandt, D. Vestweber, 2014, Journal of Investigative Dermatology.

The contribution of platelet glycoprotein receptors to inflammatory bleeding prevention is stimulus and organ dependent

S. Watson, C. Denis, B. Nieswandt, 2018, Haematologica.

Modeling and Functional Analysis of the Interaction between von Willebrand Factor A1 Domain and Glycoprotein Ibα*

S. Vasudevan, J. Ware, K. Varughese, 2000, The Journal of Biological Chemistry.

Optimization of a Recombinant von Willebrand Factor Fragment as an Antagonist of the Platelet Glycoprotein Ib Receptor

B. Cambou, J. Ware, G. Searfoss, 1993, Bio/Technology.

GPVI Potentiation of Platelet Activation by Thrombin and Adhesion Molecules Independent of Src Kinases and Syk

O. McCarty, S. Watson, J. Ware, 2006, Arteriosclerosis, thrombosis, and vascular biology.

Haploinsufficiency of the platelet P2Y12 gene in a family with congenital bleeding diathesis

J. Ware, M. Cattaneo, G. Fontana, 2009, Haematologica.

Molecular bases of defective signal transduction in the platelet P2Y12 receptor of a patient with congenital bleeding

J. Ware, P. Conley, Z. Ruggeri, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Independent assembly and secretion of a dimeric adhesive domain of von Willebrand factor containing the glycoprotein Ib-binding site.

J. Ware, H. Azuma, Z. Ruggeri, 1991, The Journal of biological chemistry.

Analysis of structure-function relationships in the platelet membrane glycoprotein Ib-binding domain of von Willebrand's factor by expression of deletion mutants.

J. Ware, Z. Ruggeri, J. Dent, 1993, The Journal of biological chemistry.

Expression of the phenotypic abnormality of platelet-type von Willebrand disease in a recombinant glycoprotein Ib alpha fragment.

S. Russell, J. Ware, M. Murata, 1993, The Journal of clinical investigation.

A Role for von Willebrand Factor Proline Residues 702-704 in Ristocetin-Mediated Binding to Platelet Glycoprotein Ib

J. Ware, H. Azuma, Z. Ruggeri, 1993, Thrombosis and Haemostasis.

Site-directed mutagenesis of a soluble recombinant fragment of platelet glycoprotein Ib alpha demonstrating negatively charged residues involved in von Willebrand factor binding.

J. Ware, M. Murata, Z. Ruggeri, 1991, The Journal of biological chemistry.

Crystal structure of the von Willebrand factor A1 domain in complex with the function blocking NMC-4 Fab

Madhusudan, J. Ware, K. Varughese, 1998, Nature Structural Biology.

Platelet clearance via shear-induced unfolding of a membrane mechanoreceptor

David S. Paul, Yan Xu, Renhao Li, 2016, Nature Communications.

Identification of Three Tyrosine Residues of Glycoprotein Ib with Distinct Roles in von Willebrand Factor and -Thrombin Binding (*)

J. Ware, M. Murata, Z. Ruggeri, 1995, The Journal of Biological Chemistry.

Adhesive properties of the isolated amino-terminal domain of platelet glycoprotein Ibalpha in a flow field.

J. Ware, Z. Ruggeri, E. Saldívar, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Modulation of α-Thrombin Function by Distinct Interactions with Platelet Glycoprotein Ibα

J. Ware, K. Varughese, Z. Ruggeri, 2003, Science.

Genetic and structural characterization of an amino acid dimorphism in glycoprotein Ib alpha involved in platelet transfusion refractoriness.

S. Russell, J. Ware, M. Murata, 1992, Blood.

Platelets at the interface of thrombosis, inflammation, and cancer.

A. Franco, J. Ware, Aime T. Franco, 2015, Blood.

Platelets: Linking Hemostasis and Cancer

J. Ware, Shashank Jain, J. Harris, 2010, Arteriosclerosis, thrombosis, and vascular biology.

A Cdc42/RhoA regulatory circuit downstream of glycoprotein Ib guides transendothelial platelet biogenesis

P. Nurden, B. Nieswandt, S. Stritt, 2017, Nature Communications.

Pathophysiology 2: The Role of Platelets in Cancer Biology.

A. Franco, J. Ware, 2019, Cancer treatment and research.

Mammalian septins nomenclature.

N. Zeleznik-Le, M. Kennedy, Y. Hayashi, 2002, Molecular biology of the cell.

Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins.

R. Hynes, D. Wagner, C. Denis, 2000, Blood.

Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhage.

R. Jain, J. Folkman, D. Wagner, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Bernard-Soulier syndrome Amelioration of the macrothrombocytopenia associated with the murine

T. Kanaji, S. Russell, J. Ware, 2013 .

Structure and expression of the human septin gene HCDCREL-1.

J. Ware, G. Roth, B. Zieger, 1998, Gene.

Alternative expression of platelet glycoprotein Ib(beta) mRNA from an adjacent 5' gene with an imperfect polyadenylation signal sequence.

J. Ware, Y. Hashimoto, B. Zieger, 1997, The Journal of clinical investigation.

Refrigeration-Induced Binding of von Willebrand Factor Facilitates Fast Clearance of Refrigerated Platelets

Renhao Li, J. Ware, C. Josephson, 2017, Arteriosclerosis, thrombosis, and vascular biology.

A Type 2b von Willebrand Disease Mutation (lle546→Val) Associated with an Unusual Phenotype

P. Mannucci, J. Ware, S. Miyata, 1997, Thrombosis and Haemostasis.

Expression of human platelet glycoprotein Ib alpha in transgenic mice.

S. Russell, J. Ware, Z. Ruggeri, 1993, The Journal of biological chemistry.

Platelet dysfunction and a high bone mass phenotype in a murine model of platelet-type von Willebrand disease.

Joshua D. Dilley, L. Suva, T. Kanaji, 2008, The American journal of pathology.

Convulxin Binds to Native, Human Glycoprotein Ibα*

T. Kanaji, J. Ware, T. Kunicki, 2003, Journal of Biological Chemistry.

Platelet glycoprotein Ibα supports experimental lung metastasis

Masahiko Zuka, S. Russell, J. Ware, 2007, Proceedings of the National Academy of Sciences.

Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells

H. Nakauchi, S. Goto, T. Kanaji, 2008, The Journal of experimental medicine.

Analysis of a large nontranscribed spacer in the ribosomal DNA of the house cricket,Acheta domesticus (Orthoptera:Gryllidae)

Z. D. Sharp, J. Ware, M. D. Cave, 1986, Biochemical Genetics.

Human septin-septin interactions as a prerequisite for targeting septin complexes in the cytosol.

L. Karlsson, J. Ware, C. Martínez, 2004, The Biochemical journal.

Structural origins of hemostasis and adaptive immunity

J. Ware, K. Varughese, 2017, Research and practice in thrombosis and haemostasis.

Fc-independent immune thrombocytopenia via mechanomolecular signaling in platelets.

Renhao Li, J. Ware, H. Ni, 2018, Blood.

Characterization and expression analysis of two human septin genes, PNUTL1 and PNUTL2.

I. Hainmann, J. Ware, B. Zieger, 2000, Gene.

Redundancy and Interaction of Thrombin- and Collagen-Mediated Platelet Activation in Tail Bleeding and Carotid Thrombosis in Mice

S. Coughlin, J. Ware, D. Duong, 2014, Arteriosclerosis, thrombosis, and vascular biology.

ATVB in Focus Platelets Unplugged: Focus on Platelet Biology

J. Ware, Shashank Jain, J. Harris, 2010 .

Platelets, glycoprotein Ib-IX, and von Willebrand factor are required for FeCl3-induced occlusive thrombus formation in the inferior vena cava of mice

Jin Xu, J. Ware, M. Fitzgerald, 2013, Platelets.

Platelet Glycoprotein Ib-IX as a Regulator of Systemic Inflammation

S. Russell, J. Ware, S. Post, 2014, Arteriosclerosis, thrombosis, and vascular biology.

von Willebrand factor.

J. Ware, Z. Ruggeri, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

filamin regulates platelet size by controlling the subcellular localization of α GPIb

T. Kanaji, J. Ware, P. Newman, 2012 .

Platelet-Dependent Inflammatory Dysregulation in Patients with Stages 4 or 5 Chronic Kidney Disease: A Mechanistic Clinical Study

J. Mehta, J. Ware, J. Arthur, 2022, Kidney360.

Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer

Caroline L. Wilson, Patrick M. Helbling, F. Tacke, 2019, Nature Medicine.

Factor IX San Dimas. Substitution of glutamine for Arg-4 in the propeptide leads to incomplete gamma-carboxylation and altered phospholipid binding properties.

B. Furie, J. Ware, D. Stafford, 1989, The Journal of biological chemistry.

Crystal structure of NMC-4 fab anti-von Willebrand factor A1 domain.

Madhusudan, J. Ware, K. Varughese, 1997, Blood cells, molecules & diseases.

A dynamic reciprocating crosstalk between cancer cells and platelets presents both opportunities and challenges for an increased understanding of tumorigenesis and improved patient therapies (1). The importance of understanding this relationship finds merit in the widespread use of cardiovascular th

J. Ware, Adam Corken, 2018 .

Viral rescue of murine Glanzmann thrombasthenia

J. Ware, 2005 .

Tumor Growth and Metastasis

J. Ware, Shashank Jain, 2013 .

Platelet-type von Willebrand disease update: the disease, the molecule and the animal model

J. Ware, M. Othman, José A López, 2011, Expert review of hematology.

Cloning and deduced amino acid sequence of human nicotinamide nucleotide transhydrogenase.

J. Ware, B. Zieger, 1997, DNA sequence : the journal of DNA sequencing and mapping.

Critical Role of Platelet Glycoprotein Ib&agr; in Arterial Remodeling

W. Schaper, B. Nieswandt, J. Ware, 2015, Arteriosclerosis, thrombosis, and vascular biology.

A binding relationship with thrombin.

J. Ware, 2016, Blood.

Platelets to hemostasis and beyond.

L. Suva, J. Ware, 2011, Blood.

Absence of GPIbα is responsible for aberrant membrane development during megakaryocyte maturation

P. Nurden, B. Nieswandt, J. Ware, 2002 .

Role for Platelet Glycoprotein Ib-IX and Effects of its Inhibition in Endotoxemia-Induced Thrombosis, Thrombocytopenia, and Mortality

Xiaoping Du, J. Ware, Z. Wang, 2013, Arteriosclerosis, Thrombosis and Vascular Biology.

Give me an intron: any intron.

J. Ware, 2013, Blood.

Platelets: Linking Hemostasis and Cancer

J. Ware, Shashank Jain, J. Harris, 2010, Arteriosclerosis, thrombosis, and vascular biology.

A comparison of washed and volume‐reduced platelets with respect to platelet activation, aggregation, and plasma protein removal

J. Bornhorst, J. Ware, M. Nakagawa, 2011, Transfusion.