P. Beauparlant

发表

Disruption of I kappa B alpha regulation by antisense RNA expression leads to malignant transformation.

N. Sonenberg, J. Hiscott, I. Kwan, 1994, Oncogene.

Skeletal Effects of Bone-Targeted TGFbeta Inhibition in a Mouse Model of Duchenne Muscular Dystrophy

F. Rauch, P. Beauparlant, J. Marulanda, 2021, Life.

Retrovirus-mediated transfer of nuclear factor-kappa B subunit genes modulates I kappa B alpha and interferon beta expression.

J. Hiscott, P. Beauparlant, R. Bitar, 1995, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Selective Inhibition of IκBα Phosphorylation and HIV-1 LTR-Directed Gene Expression by Novel Antioxidant Compounds☆

J. Hiscott, P. Beauparlant, P. Ponka, 1997 .

Bcl-2-targeted cancer therapeutics

P. Beauparlant, A. Khorchid, Amani Khorchid, 2004 .

Therapeutic Small Molecule Inhibitors of Bcl-2

P. Beauparlant, G. Shore, 2004 .

Cellular and viral protein interactions regulating IκBα activity during human retrovirus infection

H. Kwon, J. Hiscott, P. Beauparlant, 1997, Journal of leukocyte biology.

The Small Molecule GMX1778 Is a Potent Inhibitor of NAD (cid:1) Biosynthesis: Strategy for Enhanced Therapy in Nicotinic Acid Phosphoribosyltransferase 1-Deﬁcient Tumors (cid:1)

A. Roulston, K. Gilbert, P. Beauparlant, 2009 .

during human retrovirus infection

H. Kwon, J. Hiscott, P. Beauparlant, 1997 .

Preclinical development of the nicotinamide phosphoribosyl transferase inhibitor prodrug GMX1777

A. Roulston, K. Gilbert, P. Beauparlant, 2009, Anti-cancer drugs.

470 POSTER Target identification permits rational development of the prodrug GMX1777 for the treatment of melanoma

A. Roulston, P. Beauparlant, G. Shore, 2008 .

GMX1777: a novel inhibitor of NAD+ biosynthesis via inhibition of nicotinamide phosphoribosyl transferase.

A. Roulston, P. Beauparlant, G. Shore, 2007 .

Chronic human immunodeficiency virus type 1 infection stimulates distinct NF-kappa B/rel DNA binding activities in myelomonoblastic cells

J. Hiscott, A. Roulston, P. Beauparlant, 1993, Journal of virology.

The incidence of cancer associated with the treatment of rheumatoid arthritis.

P. Beauparlant, K. Papp, B. Haraoui, 1999, Seminars in arthritis and rheumatism.

Biological and biochemical inhibitors of the NF-κB/Rel proteins and cytokine synthesis

J. Hiscott, P. Beauparlant, 1996 .

The Small Molecule GMX1778 Is a Potent Inhibitor of NAD+ Biosynthesis: Strategy for Enhanced Therapy in Nicotinic Acid Phosphoribosyltransferase 1-Deficient Tumors

Karine Gilbert, Denis Paquette, Richard Marcellus, 2009, Molecular and Cellular Biology.

Regulation of human immunodeficiency virus type 1 and cytokine gene expression in myeloid cells by NF-kappa B/Rel transcription factors

M. Wainberg, J. Hiscott, A. Roulston, 1995 .

Regulation of Human Immunodeficiency Virus Type 1 and Cytokine Gene Expression in Myeloid Cells by Nf-␬b/rel Transcription Factors

M A Wainberg, M. Wainberg, J. Hiscott, 2022 .

Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis

Laurent Bélec, Ricky W. Johnstone, E. Purisima, 2007, Proceedings of the National Academy of Sciences.

Phosphorylation of IkappaBalpha in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability

J. Hiscott, S. Meloche, P. Beauparlant, 1996, Molecular and cellular biology.

Structural model of the BCL-w-BID peptide complex and its interactions with phospholipid micelles.

K. Gehring, P. Beauparlant, T. Moldoveanu, 2006, Biochemistry.

Solution Structure of Human BCL-w

K. Gehring, P. Beauparlant, G. Shore, 2003, Journal of Biological Chemistry.

Regulation of human immunodeficiency virus type 1 and cytokine gene expression in myeloid cells by NF-kappa B/Rel transcription factors

M. Wainberg, J. Hiscott, A. Roulston, 1995, Microbiological reviews.

affects intrinsic protein stability. C-terminal PEST domain by casein kinase II Phosphorylation of IkappaBalpha in the

J. Hiscott, S. Meloche, P. Beauparlant, 2013 .

Phosphorylation of I k B a in the C-Terminal PEST Domain by Casein Kinase II Affects Intrinsic Protein Stability

J. Hiscott, S. Meloche, P. Beauparlant, 1996 .

The Role of the C-terminal Domain of IB in Protein Degradation and Stabilization (*)

J. Hiscott, P. Beauparlant, R. Lin, 1996, The Journal of Biological Chemistry.

Preclinical evaluation of apoptosis induction by the novel small molecule BCL-2 inhibitor, GX015–070, in ex vivo chronic lymphoid leukemia (CLL) cells

P. Beauparlant, D. Soulières, M. Sarfati, 2005 .

Transdominant mutants of I kappa B alpha block Tat-tumor necrosis factor synergistic activation of human immunodeficiency virus type 1 gene expression and virus multiplication

N. Sonenberg, M. Wainberg, H. Kwon, 1996, Journal of virology.

, M multiplication . type 1 gene expression and virus activation of human immunodeficiency virus block Tat-tumor necrosis factor synergistic Transdominant mutants of I kappa B alpha

N. Sonenberg, M. Wainberg, H. Kwon, 1996 .

Biological and biochemical inhibitors of the NF-kappa B/Rel proteins and cytokine synthesis.

J. Hiscott, P. Beauparlant, 1996, Cytokine & growth factor reviews.

Selective inhibition of l kappaB alpha phosphorylation and HIV-1 LTR-directed gene expression by novel antioxidant compounds.

J. Hiscott, P. Beauparlant, P. Ponka, 1997, Virology.

Therapeutic activation of caspases in cancer: a question of selectivity.

P. Beauparlant, G. Shore, 2003, Current opinion in drug discovery & development.