A. Gallegos

发表

3-(Hydroxymethyl)-bearing phosphatidylinositol ether lipid analogues and carbonate surrogates block PI3-K, Akt, and cancer cell growth.

Shaomeng Wang, G. Powis, Y. Hu, 2000, Journal of medicinal chemistry.

Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase.

J. Dodge, G. Powis, R. Abraham, 1994, Cancer research.

Over-expression of DT-diaphorase in transfected NIH 3T3 cells does not lead to increased anticancer quinone drug sensitivity: a questionable role for the enzyme as a target for bioreductively activated anticancer drugs.

G. Powis, A. Gallegos, K. Sherrill, 1995, Anticancer research.

Cellular pharmacology ofd-3-azido-3-deoxy-myo-inositol, an inhibitor of phosphatidylinositol signaling having antiproliferative activity

G. Powis, A. Gallegos, A. Kozikowski, 2004, Cancer Chemotherapy and Pharmacology.

Increased expression of thioredoxin-1 in human colorectal cancer is associated with decreased patient survival.

D. Alberts, A. Bhattacharyya, G. Powis, 2003, The Journal of laboratory and clinical medicine.

Nuclear Factor κB Transactivation Is Increased But Is Not Involved in the Proliferative Effects of Thioredoxin Overexpression in MCF-7 Breast Cancer Cells

G. Powis, A. Gallegos, A. Freemerman, 1999 .

Inhibition of the signalling enzyme phosphatidylinositol-3-kinase by antitumor ether lipid analogues.

E. Modest, G. Powis, M. Berggren, 1993, Cancer research.

Advances with phospholipid signalling as a target for anticancer drug development.

G. Powis, R. Abraham, M. Berggren, 1995, Acta biochimica Polonica.

Mechanisms of the regulation of thioredoxin reductase activity in cancer cells by the chemopreventive agent selenium.

G. Powis, J. Gasdaska, M. Berggren, 1997, Cancer research.

Nuclear factor kappaB transactivation is increased but is not involved in the proliferative effects of thioredoxin overexpression in MCF-7 breast cancer cells.

G. Powis, A. Gallegos, A. Freemerman, 1999, Cancer research.

Cellular thioredoxin reductase activity is regulated by selenium.

G. Powis, J. Gasdaska, M. Berggren, 1997, Anticancer research.

Human thioredoxin reductase gene localization to chromosomal position 12q23-q24.1 and mRNA distribution in human tissue.

G. Powis, J. Gasdaska, A. Gallegos, 1996, Genomics.

Overexpression in MCF-7 Breast Cancer Cells Involved in the Proliferative Effects of Thioredoxin B Transactivation Is Increased But Is Not κ Nuclear Factor

G. Powis, A. Gallegos, A. Freemerman, 1999 .

Synthesis of D-3-deoxy-3-phosphonomethyl-myo-inositol and its dimethyl ester - compounds of use in studying the ptdins-3′-kinase signalling pathway

G. Powis, A. Gallegos, A. Kozikowski, 1993 .

3-Deoxy-D-myo-inositol 1-phosphate, 1-phosphonate, and ether lipid analogues as inhibitors of phosphatidylinositol-3-kinase signaling and cancer cell growth.

M. Kunkel, F. Nan, G. Powis, 1998, Journal of medicinal chemistry.

Novel quinone antiproliferative inhibitors of phosphatidylinositol-3-kinase.

G. Powis, R. Abraham, M. Berggren, 1995, Anti-Cancer Drug Design.

Water-soluble organotellurium compounds inhibit thioredoxin reductase and the growth of human cancer cells.

G. Powis, A. Gallegos, R. Williams, 2000, Anti-cancer drug design.

cAMP-dependent cytosolic mislocalization of p27(kip)-cyclin D1 during quinol-thioether-induced tuberous sclerosis renal cell carcinoma.

T. Monks, S. Lau, A. Gallegos, 2011, Toxicological sciences : an official journal of the Society of Toxicology.

Thioredoxin peroxidase-1 (peroxiredoxin-1) is increased in thioredoxin-1 transfected cells and results in enhanced protection against apoptosis caused by hydrogen peroxide but not by other agents including dexamethasone, etoposide, and doxorubicin.

G. Powis, M. Berggren, A. Gallegos, 2001, Archives of Biochemistry and Biophysics.

Induction of DNA damage in human urothelial cells by the brominated flame retardant 2,2-bis(bromomethyl)-1,3-propanediol: role of oxidative stress.

A. Gallegos, I. Sipes, R. Kuester, 2011, Toxicology.

In vitro and in vivo antitumor activity of the phosphatidylinositol-3-kinase inhibitor, wortmannin.

G. Powis, R. Schultz, A. Gallegos, 1995, Anticancer research.

Transfection with human thioredoxin increases cell proliferation and a dominant-negative mutant thioredoxin reverses the transformed phenotype of human breast cancer cells.

G. Paine-Murrieta, C. Taylor, G. Powis, 1996, Cancer research.

Identification of Thioredoxin-Interacting Protein 1 as a Hypoxia-Inducible Factor 1&agr;-Induced Gene in Pancreatic Cancer

D. V. Von Hoff, Huamin Wang, G. Powis, 2008, Pancreas.

Thioredoxin and thioredoxin reductase gene expression in human tumors and cell lines, and the effects of serum stimulation and hypoxia.

G. Powis, J. Gasdaska, M. Berggren, 1996, Anticancer research.

Increased intracellular Ca2+ signaling caused by the antitumor agent helenalin and its analogues

G. Powis, R. Abraham, A. Gallegos, 1994, Cancer Chemotherapy and Pharmacology.

Thioredoxin, a putative oncogene product, is overexpressed in gastric carcinoma and associated with increased proliferation and increased cell survival.

T M Grogan, R Zeheb, T. Grogan, 2000, Human pathology.

Reversible inhibition of human thioredoxin reductase activity by cytotoxic alkyl 2-imidazolyl disulfide analogues

G. Powis, A. Gallegos, Tao Chen, 2004, Cancer Chemotherapy and Pharmacology.

Pharmacokinetic studies of the herbicide and antitumor compound oryzalin in mice.

G. Powis, A. Gallegos, R. Dorr, 1997, Journal of chromatography. B, Biomedical sciences and applications.

A novel small molecule inhibitor of the DNA repair protein Ku70/80.

L. Cooke, D. Mahadevan, A. Gallegos, 2016, DNA repair.

Inhibition of intracellular Ca2+ signalling, cytotoxicity and antitumor activity of the herbicide oryzalin and its analogues

G. Powis, R. Abraham, A. Gallegos, 1997, Cancer Chemotherapy and Pharmacology.

Estrogen binding, receptor mRNA, and biologic response in osteoblast-like osteosarcoma cells.

B. Komm, M. Korc, M. Haussler, 1988, Science.

Identification of Thioredoxin-Interacting Protein 1 as a Hypoxia-Inducible Factor 1&agr;-Induced Gene in Pancreatic Cancer

D. V. Von Hoff, Huamin Wang, G. Powis, 2008, Pancreas.