B. Rowan

发表

The Gαi and Gαq proteins mediate the effects of melatonin on steroid/thyroid hormone receptor transcriptional activity and breast cancer cell proliferation

S. Hill, L. Lai, Lin Yuan, 2008, Journal of pineal research.

Post-translational modifications of nuclear receptors and human disease

Leigh Murphy, L. Murphy, B. Rowan, 2012, Nuclear receptor signaling.

Estrogen receptor alpha phosphorylation and its functional impact in human breast cancer

B. Rowan, Muralidharan Anbalagan, M. Anbalagan, 2015, Molecular and Cellular Endocrinology.

Insulin and IGF1 enhance IL‐17‐induced chemokine expression through a GSK3B‐dependent mechanism: a new target for melatonin's anti‐inflammatory action

S. Hill, G. Brainard, J. Hanifin, 2013, Journal of pineal research.

Argonaute 2 Expression Correlates with a Luminal B Breast Cancer Subtype and Induces Estrogen Receptor Alpha Isoform Variation

K. Nephew, B. Rowan, E. Martin, 2016, Non-coding RNA.

CD4+ T helper 17 cell response of aged mice promotes prostate cancer cell migration and invasion

S. Jazwinski, O. Sartor, A. Abdel‐Mageed, 2020, The Prostate.

Evolution and future prospects of adipose-derived immunomodulatory cell therapeutics

J. Gimble, B. Rowan, K. Mcintosh, 2013, Expert review of clinical immunology.

Mutant Glucocorticoid Receptors in Lymphoma a

B. Rowan, M. Ip, W. Shea, 1993, Annals of the New York Academy of Sciences.

Cell growth characteristics, differentiation frequency, and immunophenotype of adult ear mesenchymal stem cells.

J. Gimble, B. Rowan, E. Chiu, 2010, Stem cells and development.

Suppression of triple-negative breast cancer metastasis by pan-DAC inhibitor panobinostat via inhibition of ZEB family of EMT master regulators

D. Chrisey, B. Rowan, L. Rhodes, 2014, Breast Cancer Research and Treatment.

Decreased folylpolyglutamate synthetase activity as a mechanism of methotrexate resistance in CCRF-CEM human leukemia sublines.

J. Bertino, B. Rowan, E. Mini, 1991, The Journal of biological chemistry.

Combination of methylselenocysteine with tamoxifen inhibits MCF-7 breast cancer xenografts in nude mice through elevated apoptosis and reduced angiogenesis

B. Rowan, M. Burow, A. Thiyagarajah, 2009, Breast Cancer Research and Treatment.

Novel bone-targeted parathyroid hormone-related peptide antagonists inhibit breast cancer bone metastases

B. Rowan, Muralidharan Anbalagan, R. Stratford, 2021, Anti-cancer drugs.

Subcellular Localization of Total and Activated Src Kinase in African American and Caucasian Breast Cancer

B. Rowan, K. Moroz, Muralidharan Anbalagan, 2012, PloS one.

p38 mitogen-activated protein kinase stimulates estrogen-mediated transcription and proliferation through the phosphorylation and potentiation of the p160 coactivator glucocorticoid receptor-interacting protein 1.

T. Curiel, J. McLachlan, P. Kushner, 2006, Molecular endocrinology.

Methylseleninic acid synergizes with tamoxifen to induce caspase-mediated apoptosis in breast cancer cells

B. Rowan, Zengshan Li, Latonya M Carrier, 2008, Molecular Cancer Therapeutics.

Analysis of receptor phosphorylation.

N. Weigel, B. Rowan, R. Narayanan, 2003, Methods in enzymology.

Attenuation of estrogen receptor alpha (ERalpha) signaling by selenium in breast cancer cells via downregulation of ERalpha gene expression.

C. Ip, B. Rowan, Y. Shah, 2005, Breast cancer research and treatment.

Breast Cancer Reconstruction: Design Criteria for a Humanized Microphysiological System.

J. Gimble, B. Rowan, E. Martin, 2021, Tissue engineering. Part A.

Protein kinase A exhibits selective modulation of estradiol-dependent transcription in breast cancer cells that is associated with decreased ligand binding, altered estrogen receptor alpha promoter interaction, and changes in receptor phosphorylation.

M. Al-Dhaheri, B. Rowan, 2007, Molecular endocrinology.

Body mass index affects proliferation and osteogenic differentiation of human subcutaneous adipose tissue-derived stem cells

J. Gimble, B. Rowan, E. Chiu, 2013, BMC Cell Biology.

Mechanistic differences in the activation of estrogen receptor-alpha (ER alpha)- and ER beta-dependent gene expression by cAMP signaling pathway(s).

Carolyn L. Smith, N. Weigel, B. Rowan, 2003, The Journal of biological chemistry.

Adipose Stem Cell Therapy in Cancer Reconstruction: A Critical Review

J. Gimble, P. Friedlander, B. Rowan, 2014, Annals of plastic surgery.

Identification and localization of steroid-binding and nonsteroid-binding forms of the glucocorticoid receptor in the mouse P1798 lymphosarcoma

B. Rowan, M. Ip, 1995, The Journal of Steroid Biochemistry and Molecular Biology.

Co-activators and Corepressors for the Nuclear Receptor Superfamily

B. Rowan, 2003 .

Detection of ERalpha-SRC-1 interactions using bioluminescent resonance energy transfer.

B. Rowan, T. Duplessis, Kristen L. Koterba, 2009, Methods in molecular biology.

Identification of four novel phosphorylation sites in estrogen receptor α : impact on receptor-dependent gene expression and phosphorylation by protein kinase CK 2

Carolyn L. Smith, B. Rowan, A. El-Gharbawy, 2015 .

Melatonin inhibits mitogenic cross-talk between retinoic acid-related orphan receptor alpha (RORα) and ERα in MCF-7 human breast cancer cells

S. Hill, L. Lai, Lin Yuan, 2010, Steroids.

Impact of low oxygen on the secretome of human adipose-derived stromal/stem cell primary cultures.

J. Gimble, B. Rowan, I. Kheterpal, 2013, Biochimie.

Attenuation of Estrogen Receptor α (ERα) Signaling by Selenium in Breast Cancer Cells via Downregulation of ERα Gene Expression

C. Ip, B. Rowan, Y. Shah, 2005, Breast Cancer Research and Treatment.

A Novel Controlled PTEN-Knockout Mouse Model for Prostate Cancer Study

T. Niu, S. Jazwinski, O. Sartor, 2021, Frontiers in Molecular Biosciences.

Necroptosis of tumor cells leads to tumor necrosis and promotes tumor metastasis

Chengyu Liu, B. Rowan, S. Choksi, 2018, Cell Research.

Adipose-derived stromal/stem cells

J. Gimble, B. Rowan, Xiying Wu, 2013, Organogenesis.

Human Adipose Tissue-Derived Stromal/Stem Cells Promote Migration and Early Metastasis of Head and Neck Cancer Xenografts.

J. Gimble, P. Friedlander, B. Rowan, 2016, Aesthetic surgery journal.

Progesterone receptor coactivators

B. O’Malley, B. Rowan, 2000, Steroids.

Human Adipose Tissue-Derived Stromal/Stem Cells Promote Migration and Early Metastasis of Triple Negative Breast Cancer Xenografts

J. Gimble, R. Kutner, P. Friedlander, 2014, PloS one.

Disseminated Breast Cancer Cells Acquire a Highly Malignant and Aggressive Metastatic Phenotype during Metastatic Latency in the Bone

C. Marsden, B. Rowan, K. Moroz, 2012, PloS one.

Methylseleninic Acid Enhances Paclitaxel Efficacy for the Treatment of Triple-Negative Breast Cancer

S. Hill, Xueqi Fu, B. Rowan, 2012, PloS one.

Telomerase as an Important Target of Androgen Signaling Blockade for Prostate Cancer Treatment

Yubin Ge, Paul S. Rennie, Izumi Horikawa, 2010, Molecular Cancer Therapeutics.

Expression of estrogen receptor coregulators in normal and malignant human endometrium.

B. Rowan, M. Desouki, Sharif M Kershah, 2004, Gynecologic oncology.

B. Rowan, A. Basu, 2005, Frontiers in bioscience : a journal and virtual library.

Necroptosis of tumor cells leads to tumor necrosis and promotes tumor metastasis

Chengyu Liu, B. Rowan, Chengyu Liu, 2018, Cell Research.

Adult human mesenchymal stem cells enhance breast tumorigenesis and promote hormone independence

M. Lacey, R. Pochampally, J. McLachlan, 2010, Breast Cancer Research and Treatment.

ERα and ERK1/2 MAP kinase expression in microdissected stromal and epithelial endometrial cells.

B. Rowan, M. Desouki, I. S. Atta, 2014, Journal of the Egyptian National Cancer Institute.

Dichotomous roles for the orphan nuclear receptor NURR1 in breast cancer

B. Rowan, T. Duplessis, Shawn D. Llopis, 2013, BMC Cancer.

Measuring ligand-dependent and ligand-independent interactions between nuclear receptors and associated proteins using Bioluminescence Resonance Energy Transfer (BRET2)

B. Rowan, Kristen L. Koterba, 2006, Nuclear receptor signaling.

Dual Src Kinase/Pretubulin Inhibitor KX-01, Sensitizes ERα-negative Breast Cancers to Tamoxifen through ERα Reexpression

B. Rowan, B. Collins-Burow, M. Burow, 2017, Molecular Cancer Research.

Phosphorylation of Steroid Receptor Coactivator-1

B. O’Malley, N. Weigel, B. Rowan, 2000, The Journal of Biological Chemistry.

Activation of autophagy in mesenchymal stem cells provides tumor stromal support.

R. Pochampally, B. Rowan, D. Krause, 2011, Carcinogenesis.

Methylseleninic acid is a novel suppressor of aromatase expression.

D. Edwards, M. Wabitsch, Y. Nishi, 2012, The Journal of endocrinology.

Selenium disrupts estrogen receptor α signaling and potentiates tamoxifen antagonism in endometrial cancer cells and tamoxifen-resistant breast cancer cells

M. Al-Dhaheri, C. Ip, B. Rowan, 2005, Molecular Cancer Therapeutics.

Mechanistic Differences in the Activation of Estrogen Receptor-α (ERα)- and ERβ-dependent Gene Expression by cAMP Signaling Pathway(s)*

Carolyn L. Smith, N. Weigel, B. Rowan, 2003, The Journal of Biological Chemistry.

Epidermal growth factor suppresses induction by progestin of the adhesion protein desmoplakin in T47D breast cancer cells

M. Al-Dhaheri, B. Rowan, L. E. Faber, 2004, Breast Cancer Research.

Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor

S. Hill, O. Sartor, Q. Lin, 2016, Oncotarget.

Gαo potentiates estrogen receptor α activity via the ERK signaling pathway.

Yan Tang, S. Hill, J. Alam, 2012, The Journal of endocrinology.

ERK5 Is Required for Tumor Growth and Maintenance Through Regulation of the Extracellular Matrix in Triple Negative Breast Cancer

K. Nephew, L. Del Valle, Jane E. Cavanaugh, 2020, Frontiers in Oncology.

The relevance of phosphorylated forms of estrogen receptor in human breast cancer in vivo

L. Murphy, P. Watson, M. Al-Dhaheri, 2009, The Journal of Steroid Biochemistry and Molecular Biology.

8-Bromo-Cyclic AMP Induces Phosphorylation of Two Sites in SRC-1 That Facilitate Ligand-Independent Activation of the Chicken Progesterone Receptor and Are Critical for Functional Cooperation between SRC-1 and CREB Binding Protein

N. Weigel, B. Rowan, Bert W. O’Malley, 2000, Molecular and Cellular Biology.

Ligand-and Phosphorylation-dependent Modulation of Estrogen Receptor Target Gene Expression Submitted

M. Al-Dhaheri, S. Najjar, B. Rowan, 2006 .

Molecular and Cellular Pathobiology Interleukin-17 Promotes Formation and Growth of Prostate Adenocarcinoma in Mouse Models

Oliver Sartor, Jonathan Melamed, Leann Myers, 2012 .

Modulation of the folate receptor alpha gene by the estrogen receptor: mechanism and implications in tumor targeting.

B. Rowan, M. Ratnam, K. Kelley, 2003, Cancer research.

G a potentiates estrogen receptor o a activity via the ERK signaling pathway

Yan Tang, S. Hill, J. Alam, 2012 .

Selective estrogen receptor modulator regulated proteins in endometrial cancer cells

B. Rowan, V. Basrur, Y. Shah, 2004, Molecular and Cellular Endocrinology.

A novel mouse model of metastatic thyroid carcinoma using human adipose tissue-derived stromal/stem cells.

J. Gimble, P. Friedlander, E. Kandil, 2013, Anticancer research.

"A novel in vivo model for the study of human breast cancer metastasis using primary breast tumor-initiating cells from patient biopsies"

C. Marsden, R. Pochampally, B. Rowan, 2012, BMC Cancer.

Dual inhibition of MEK1/2 and MEK5 suppresses the EMT/migration axis in triple‐negative breast cancer through FRA‐1 regulation

K. Nephew, D. Rusch, D. Chrisey, 2021, Journal of cellular biochemistry.

The Src kinase pathway promotes tamoxifen agonist action in Ishikawa endometrial cells through phosphorylation-dependent stabilization of estrogen receptor (alpha) promoter interaction and elevated steroid receptor coactivator 1 activity.

B. Rowan, Y. Shah, 2005, Molecular endocrinology.

Genetic and epigenetic alterations of steroidogenic factor-1 in ovarian tumors

N. Makridakis, B. Rowan, K. Moroz, 2012, International journal of oncology.

Differential binding of mutant glucocorticoid receptors to the glucocorticoid response element of the tyrosine aminotransferase gene

B. Rowan, M. Ip, 1996, The Journal of Steroid Biochemistry and Molecular Biology.

Differential Phosphorylation of Chicken Progesterone Receptor in Hormone-dependent and Ligand-independent Activation*

B. O’Malley, N. Weigel, B. Rowan, 1997, The Journal of Biological Chemistry.

Stable inhibition of specific estrogen receptor α (ERα) phosphorylation confers increased growth, migration/invasion, and disruption of estradiol signaling in MCF-7 breast cancer cells.

C. Marsden, S. Hill, B. Rowan, 2012, Endocrinology.

A phosphorylation code for oestrogen receptor-alpha predicts clinical outcome to endocrine therapy in breast cancer.

L. Murphy, P. Watson, B. Rowan, 2010, Endocrine-related cancer.

Immunohistochemical validation of multiple phospho-specific epitopes for estrogen receptor α (ERα) in tissue microarrays of ERα positive human breast carcinomas

L. Murphy, P. Watson, M. Al-Dhaheri, 2009, Breast Cancer Research and Treatment.

Identification of novel proteins induced by estradiol, 4-hydroxytamoxifen and acolbifene in T47D breast cancer cells

M. Al-Dhaheri, B. Rowan, V. Basrur, 2006, Steroids.

Application of phosphorylation site-specific antibodies to measure nuclear receptor signaling: characterization of novel phosphoantibodies for estrogen receptor α

M. Al-Dhaheri, B. Rowan, 2006, Nuclear receptor signaling.

Src Kinase and Mitogen-Activated Protein Kinases in the Progression from Normal to Malignant Endometrium

B. Rowan, M. Desouki, 2004, Clinical Cancer Research.

KX-01, a novel Src kinase inhibitor directed toward the peptide substrate site, synergizes with tamoxifen in estrogen receptor α positive breast cancer

B. Shan, B. Rowan, D. Hangauer, 2012, Breast Cancer Research and Treatment.

Phosphorylation of Estrogen Receptor α at serine 118 directs recruitment of promoter complexes and gene-specific transcription.

S. Hill, B. Rowan, T. Duplessis, 2011, Endocrinology.

Circadian and melatonin disruption by exposure to light at night drives intrinsic resistance to tamoxifen therapy in breast cancer.

Lin Yuan, Tripp Frasch, S. Hill, 2014, Cancer research.

Body mass index affects proliferation and osteogenic differentiation of human subcutaneous adipose tissue-derived stem cells

J. Gimble, B. Rowan, E. Chiu, 2013, BMC Cell Biology.

Charge heterogeneity in wildtype and variant glucocorticoid receptors

B. Rowan, M. Ip, 1995, Molecular and Cellular Endocrinology.

Human steroidogenic factor-1 (hSF-1) regulates progesterone biosynthesis and growth of ovarian surface epithelial cancer cells

S. Hill, B. Rowan, K. Moroz, 2010, The Journal of Steroid Biochemistry and Molecular Biology.

Peptidomimetic Src/Pretubulin Inhibitor KX-01 Alone and in Combination with Paclitaxel Suppresses Growth, Metastasis in Human ER/PR/HER2-Negative Tumor Xenografts

C. Marsden, B. Rowan, D. Hangauer, 2012, Molecular Cancer Therapeutics.

Hypochlorous Acid: A Review

B. Rowan, M. Block, B. Rowan, 2020, Journal of Oral and Maxillofacial Surgery.

C. elegans nuclear receptor NHR‐6 functionally interacts with the jun‐1 transcription factor during spermatheca development

B. Rowan, C. R. Gissendanner, Jeremy S. Harmson, 2014, Genesis.

Preclinical Development Peptidomimetic Src / Pretubulin Inhibitor KX-01 Alone and in Combination with Paclitaxel Suppresses Growth , Metastasis in Human ER / PR / HER 2-Negative Tumor Xenografts

C. Marsden, B. Rowan, D. Hangauer, 2012 .

Human adipose-derived stromal/stem cells induce functional CD4+CD25+FoxP3+CD127- regulatory T cells under low oxygen culture conditions.

J. Gimble, B. Rowan, J. McLachlan, 2014, Stem cells and development.

Post-translational modifications of nuclear receptors and human disease.

L. Murphy, B. Rowan, B. Huderson, 2012 .

A functional NR4A nuclear receptor DNA‐binding domain is required for organ development in Caenorhabditis elegans

C. V. Maina, T. Q. Nguyen, B. Rowan, 2010, Genesis.

Novel phosphorylation target in the serum response factor MADS box regulates alpha-actin transcription.

R. Schwartz, F. Booth, N. Weigel, 2003, Biochemistry.

A phosphorylation code for oestrogen receptor-alpha predicts clinical outcome to endocrine therapy in breast cancer.

L. Murphy, P. Watson, B. Rowan, 2010, Endocrine-related cancer.

Drug resistance profiling of a new triple negative breast cancer patient-derived xenograft model

B. Rowan, E. Martin, L. Rhodes, 2019, BMC Cancer.

Stable inhibition of specific estrogen receptor α (ERα) phosphorylation confers increased growth, migration/invasion, and disruption of estradiol signaling in MCF-7 breast cancer cells.

B. Rowan, B. Huderson, T. Duplessis, 2012, Endocrinology.

Breast tumor-initiating cells isolated from patient core biopsies for study of hormone action.

C. Marsden, R. Pochampally, B. Rowan, 2009, Methods in molecular biology.

Molecular and Cellular Pathobiology Interleukin-17 Promotes Formation and Growth of Prostate Adenocarcinoma in Mouse Models

Q. Zhang, J. Melamed, S. Hill, 2012 .

Methylseleninic acid synergizes with tamoxifen to induce caspase-mediated apoptosis in breast cancer cells

B. Rowan, Zengshan Li, Latonya M Carrier, 2008, Molecular Cancer Therapeutics.