C. Nanoff

发表

Dual signaling of human Mel1a melatonin receptors via G(i2), G(i3), and G(q/11) proteins.

A. Strosberg, P. Morgan, R. Jockers, 1999, Molecular endocrinology.

Hyponatremia and V2 vasopressin receptor upregulation: a result of HSP90 inhibition

M. Freissmuth, C. Nanoff, Qiong Yang, 2017, Cancer Chemotherapy and Pharmacology.

Biased inhibition by a suramin analogue of A1-adenosine receptor/G protein coupling in fused receptor/G protein tandems: the A1-adenosine receptor is predominantly coupled to Goα in human brain

M. Freissmuth, C. Nanoff, M. Waldhoer, 2001, Naunyn-Schmiedeberg's Archives of Pharmacology.

Truncation of the A1 Adenosine Receptor Reveals Distinct Roles of the Membrane-proximal Carboxyl Terminus in Receptor Folding and G Protein Coupling*

M. Freissmuth, C. Nanoff, Halyna Pankevych, 2003, Journal of Biological Chemistry.

Functional Impact of the G279S Substitution in the Adenosine A1-Receptor (A1R-G279S7.44), a Mutation Associated with Parkinson’s Disease

T. Stockner, M. Freissmuth, C. Nanoff, 2020, Molecular Pharmacology.

Adenosine receptors: G protein-mediated signalling and the role of accessory proteins.

M. Freissmuth, C. Nanoff, M. Klinger, 2002, Cellular signalling.

Relax, Cool Down and Scaffold: How to Restore Surface Expression of Folding-Deficient Mutant GPCRs and SLC6 Transporters

M. Freissmuth, C. Nanoff, S. Sucic, 2017, International journal of molecular sciences.

Mapping of Calmodulin and Gβγ Binding Domains within the C-terminal Region of the Metabotropic Glutamate Receptor 7A*

V. O'Connor, M. Freissmuth, C. Nanoff, 2001, The Journal of Biological Chemistry.

Suramin analogues as subtype-selective G protein inhibitors.

A. IJzerman, M. Hohenegger, M. Freissmuth, 1996, Molecular pharmacology.

Solubilization and characterization of the A2-adenosine receptor.

G. Stiles, C. Nanoff, 1993, Journal of receptor research.

Species difference in the G protein selectivity of the human and bovine A1-adenosine receptor.

A. Strosberg, M. Hohenegger, S. Marullo, 1994, The Journal of biological chemistry.

The noradrenaline transporter as site of action for the anti-Parkinson drug amantadine

C. Nanoff, C. Pifl, P. Rebernik, 2012, Neuropharmacology.

Suramin and the suramin analogue NF307 discriminate among calmodulin-binding sites.

M. Hohenegger, M. Freissmuth, C. Nanoff, 2001, The Biochemical journal.

G Protein coupling of the rat A1-adenosine receptor—Partial purification of a protein which stabilizes the receptor-G protein association

M. Freissmuth, F. Roka, C. Nanoff, 1997, Neuropharmacology.

Species differences in A1 adenosine receptor/G protein coupling: identification of a membrane protein that stabilizes the association of the receptor/G protein complex.

M. Hohenegger, M. Freissmuth, F. Roka, 1995, Molecular pharmacology.

Pharmacochaperoning of the A1 Adenosine Receptor Is Contingent on the Endoplasmic Reticulum

M. Freissmuth, C. Nanoff, J. Bauer, 2010, Molecular Pharmacology.

Two different signaling mechanisms involved in the excitation of rat sympathetic neurons by uridine nucleotides.

M. Freissmuth, C. Nanoff, S. Boehm, 2000, Molecular pharmacology.

Comparison of the β-Adrenergic Receptor Antagonists Landiolol and Esmolol: Receptor Selectivity, Partial Agonism, and Pharmacochaperoning Actions

M. Freissmuth, C. Nanoff, S. Sucic, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Desensitization pattern of cardiac β-adrenoceptor subtypes by prolonged in vivo infusion of pindolol and celiprolol in rats

W. Schütz, C. Nanoff, M. Ströher, 2005, Basic Research in Cardiology.

Differences in the GTP-regulation of membrane-bound and solubilized A1-adenosine receptors

W. Schütz, C. Nanoff, M. Ströher, 1989, Naunyn-Schmiedeberg's Archives of Pharmacology.

Glomeruli and microvessels of the rabbit kidney contain both A1- and A2-adenosine receptors

W. Schütz, M. Freissmuth, C. Nanoff, 1987, Naunyn-Schmiedeberg's Archives of Pharmacology.

G protein antagonists.

M. Freissmuth, C. Nanoff, M. Waldhoer, 1999, Trends in pharmacological sciences.

Removal of the carboxy terminus of the A2A-adenosine receptor blunts constitutive activity: differential effect on cAMP accumulation and MAP kinase stimulation

T. Palmer, M. Freissmuth, C. Nanoff, 2002, Naunyn-Schmiedeberg's Archives of Pharmacology.

Metal-dependent nucleotide binding to the Escherichia coli rotamase SlyD.

M. Hohenegger, H. Ahorn, M. Freissmuth, 1999, The Biochemical journal.

The A2 adenosine receptor: guanine nucleotide modulation of agonist binding is enhanced by proteolysis.

K. Jacobson, G. Stiles, C. Nanoff, 1991, Molecular pharmacology.

Constitutive activity of the A2A adenosine receptor and compartmentalised cyclic AMP signalling fine-tune noradrenaline release

T. Höfer, C. Nanoff, S. Boehm, 2012, Purinergic Signalling.

The role of a low β1-adrenoceptor selectivity of [3H]CGP-12177 for resolving subtype-selectivity of competitive ligands

W. Schütz, M. Freissmuth, C. Nanoff, 1987, Naunyn-Schmiedeberg's Archives of Pharmacology.

The fallacy of non-selectivity of radioactive ligands

W. Schütz, M. Freissmuth, C. Nanoff, 1988 .

The Carboxyl Terminus of the Gα-Subunit Is the Latch for Triggered Activation of Heterotrimeric G Proteins

H. Ahorn, M. Freissmuth, C. Nanoff, 2006, Molecular Pharmacology.

The carboxyl terminus of the Galpha-subunit is the latch for triggered activation of heterotrimeric G proteins.

H. Ahorn, M. Freissmuth, C. Nanoff, 2006, Molecular pharmacology.

A Different Desensitization Pattern of Cardiac β‐Adrenoceptor Subtypes by Prolonged In Vivo Infusion of Isoprenaline

M. Freissmuth, C. Nanoff, W. Schútz, 1989, Journal of cardiovascular pharmacology.

P2‐, but not P1‐purinoceptors mediate formation of 1,4,5‐inositol trisphosphate and its metabolites via a pertussis toxin‐insensitive pathway in the rat renal cortex

W. Schütz, M. Freissmuth, C. Nanoff, 1990, British journal of pharmacology.

Tight association of the human Mel(1a)-melatonin receptor and G(i): precoupling and constitutive activity.

A. Strosberg, A. Strosberg, M. Freissmuth, 1999, Molecular pharmacology.

Limitations in Adjuvant Breast Cancer Therapy: The Predictive Potential of Pharmacogenetics and Pharmacogenomics

C. Nanoff, P. Thurner, 2008, Breast Care.

Chaperoning of the A1-Adenosine Receptor by Endogenous Adenosine—An Extension of the Retaliatory Metabolite Concept

M. Freissmuth, C. Nanoff, C. Gruber, 2015, Molecular Pharmacology.

Chaperoning of the A 1-Adenosine Receptor by Endogenous Adenosine — An Extension of the Retaliatory Metabolite Concept s

M. Freissmuth, C. Nanoff, C. Gruber, 2014 .

Stimulation of adenylate cyclase activity via A2-adenosine receptors in isolated tubules of the rabbit renal cortex.

M. Freissmuth, C. Nanoff, W. Schuetz, 1987, European journal of pharmacology.

The Ubiquitin-Specific Protease Usp4 Regulates the Cell Surface Level of the A2a Receptor

M. Freissmuth, C. Nanoff, E. Ogris, 2006, Molecular Pharmacology.

Calmodulin dependence of presynaptic metabotropic glutamate receptor signaling.

V. O'Connor, A. Karschin, M. Freissmuth, 1999, Science.

The Human D2 Dopamine Receptor Synergizes with the A2A Adenosine Receptor to Stimulate Adenylyl Cyclase in PC12 Cells

M. Freissmuth, C. Nanoff, V. M. Korkhov, 2003, Neuropsychopharmacology.

G protein-dependent signalling and ageing☆

M. Freissmuth, F. Roka, C. Nanoff, 2000, Experimental Gerontology.

Gsalpha-selective G protein antagonists.

M. Hohenegger, M. Freissmuth, C. Nanoff, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Inhibition of receptor/G protein coupling by suramin analogues.

A. IJzerman, M. Hohenegger, M. Freissmuth, 1996, Molecular pharmacology.

G proteins as drug targets

M. Freissmuth, C. Nanoff, W. Beindl, 1999, Cellular and Molecular Life Sciences CMLS.

Differential uncoupling of A1 adenosine and D2 dopamine receptors by suramin and didemethylated suramin (NF037).

G. Milligan, M. Freissmuth, C. Nanoff, 1998, Molecular pharmacology.

Differential Uncoupling of A 1 Adenosine and D 2 Dopamine Receptors by Suramin and Didemethylated Suramin ( NF 037 )

G. Milligan, M. Freissmuth, C. Nanoff, 1998 .

The Ubiquitin-Specific Protease Usp 4 Regulates the Cell Surface Level of the A 2 a Receptor

M. Freissmuth, C. Nanoff, E. Ogris, 2006 .

ER-bound steps in the biosynthesis of G protein-coupled receptors.

M. Freissmuth, C. Nanoff, 2012, Sub-cellular biochemistry.

Covalent modification of G-proteins by affinity labeling.

M. Hohenegger, M. Freissmuth, C. Nanoff, 2004, Methods in molecular biology.

Structural and functional characterization of the interaction between 2',3'-dialdehyde guanine nucleotide analogues and the stimulatory G protein alpha-subunit.

M. Hohenegger, H. Ahorn, M. Freissmuth, 1994, The Journal of biological chemistry.

Fluorescence resonance energy transfer (FRET) sensors

C. Nanoff, O. Kudlacek, I. Gsandtner, 2008, BMC Pharmacology.

Sensitization of Dopamine‐Stimulated Adenylyl Cyclase in the Striatum of 1‐Methyl‐4‐Phenyl‐1,2,3,6‐Tetrahydropyridine‐Treated Rhesus Monkeys and Patients with Idiopathic Parkinson's Disease

O. Hornykiewicz, W. Schütz, C. Nanoff, 1992, Journal of neurochemistry.

A Two-state Model for the Diffusion of the A2A Adenosine Receptor in Hippocampal Neurons

D. Choquet, J. Zezula, M. Freissmuth, 2014, The Journal of Biological Chemistry.

Coupling cofactor--a novel regulatory component in G protein-mediated signalling?

M. Freissmuth, C. Nanoff, 1997, Physiological research.

Sensitization of cAMP formation in a neuron-like cell line

C. Nanoff, M. Bilban, Edin Ibrišimović, 2007 .

The C2 catalytic domain of adenylyl cyclase contains the second metal ion (Mn2+) binding site.

M. Hohenegger, M. Freissmuth, C. Nanoff, 1998, Biochemistry.

Inhibition of Adenylyl and Guanylyl Cyclase Isoforms by the Antiviral Drug Foscarnet*

M. Hohenegger, Wei-Jen Tang, M. Freissmuth, 2001, The Journal of Biological Chemistry.

Development of Gs-selective inhibitory compounds.

M. Freissmuth, C. Nanoff, O. Kudlacek, 2002, Methods in enzymology.

2',3'-Dialdehyde GTP as an irreversible G protein antagonist. Disruption and reconstitution of G protein-mediated signal transduction in cells and cell membranes.

M. Hohenegger, W. Schütz, M. Freissmuth, 1994, The Journal of biological chemistry.

Recruitment of a Cytoplasmic Chaperone Relay by the A2A Adenosine Receptor

M. Freissmuth, C. Nanoff, C. Gruber, 2013, The Journal of Biological Chemistry.

Constitutive activity of the A2A adenosine receptor and compartmentalised cyclic AMP signalling fine-tune noradrenaline release

T. Höfer, C. Nanoff, S. Boehm, 2012, Purinergic Signalling.

Functional impact of the G279S substitution in the adenosine A1-receptor (A1R-G279S), a mutation associated with Parkinson's disease.

T. Stockner, M. Freissmuth, C. Nanoff, 2020, Molecular pharmacology.

Functional Impact of the G 279 S Substitution in the Adenosine A 1-Receptor ( A 1 RG 279 S 7 . 44 ) , a Mutation Associated with Parkinson ’ s Disease

T. Stockner, M. Freissmuth, C. Nanoff, 2020 .

The value of [11C]-acetate PET and [18F]-FDG PET in hepatocellular carcinoma before and after treatment with transarterial chemoembolization and bevacizumab

W. Wadsak, M. Mitterhauser, A. Haug, 2017, European Journal of Nuclear Medicine and Molecular Imaging.

Beyond G proteins: The role of accessory proteins in G protein-coupled receptor signalling

B. Nürnberg, M. Freissmuth, C. Nanoff, 2002 .

Kinetics of Ternary Complex Formation with Fusion Proteins Composed of the A1-Adenosine Receptor and G Protein α-Subunits*

G. Milligan, M. Freissmuth, C. Nanoff, 1999, The Journal of Biological Chemistry.

Binding of Calmodulin to the D2-Dopamine Receptor Reduces Receptor Signaling by Arresting the G Protein Activation Switch*

H. Ahorn, M. Freissmuth, C. Nanoff, 2000, The Journal of Biological Chemistry.

Thiophosphorylation of the G protein beta subunit in human platelet membranes: evidence against a direct phosphate transfer reaction to G alpha subunits.

T. Voss, C. Nanoff, T. Mitterauer, 1996, Molecular pharmacology.