J. Herbert

J. Herbert, D. Hoppensteadt, J. Fareed, 1999, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

Effect of glycoprotein IIb/IIIa antagonists on the HIT serum induced activation of platelets.

J. Herbert, W. Jeske, J. Walenga, 1997, Thrombosis research.

Effect of Clopidogrel on Thrombin Generation in Platelet-Rich Plasma in the Rat

J. Herbert, J. Hérault, A. Bernat, 1999, Thrombosis and Haemostasis.

CEP-7055: a novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models.

A. Klein-Szanto, P. Casellas, P. Dobrzanski, 2003, Cancer research.

Clopidogrel enhancement of rt-PA thrombolysis in a thrombo-embolic model of cerebral ischemia in rats

J. Herbert, P. Pottier, A. Bernat, 1998 .

Regulation of 5-hydroxytryptamine2 (5-HT2) receptor expression in cultured rat aortic smooth muscle cells by SR 46349B, a selective 5-HT2 receptor antagonist.

P. Casellas, J. Herbert, M. Rinaldi-Carmona, 1994, The Journal of biological chemistry.

Activity of pentosan polysulphate and derived compounds on vascular endothelial cell proliferation and migration induced by acidic and basic FGF in vitro.

J. Herbert, J. Maffrand, M. Cottineau, 1988, Biochemical pharmacology.

Clopidogrel inhibition of stent, graft, and vascular thrombogenesis with antithrombotic enhancement by aspirin in nonhuman primates.

S. Hanson, J. Herbert, L. Harker, 1998, Circulation.

Effect of aspirin and clopidogrel on platelet-dependent tissue factor expression in endothelial cells.

J. Herbert, P. Savi, A. Bernat, 1994, Thrombosis research.

NGF exhibits a pro‐apoptotic activity for human vascular smooth muscle cells that is inhibited by TGFβ1

J. Herbert, F. Bono, I. Lamarche, 1997, FEBS letters.

Fondaparinux, a synthetic pentasaccharide: the first in a new class of antithrombotic agents - the selective factor Xa inhibitors.

D. W. Hawkins, J. Herbert, K. Bauer, 2006, Cardiovascular drug reviews.

The Effect of a Novel Glycoprotein IIb/IIIa Antagonist, SR 121566A, on Platelet Aggregation and Activation in Rhesus Monkeys

J. Herbert, D. Hoppensteadt, J. Fareed, 2001, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

Effects of differential blockade of the renin‐angiotensin system in postinfarcted rats

J. Herbert, D. Nisato, C. Roque, 2004, Fundamental & clinical pharmacology.

Thrombin induces endothelial cell growth via both a proteolytic and a non-proteolytic pathway.

J. Herbert, Shavit, G. Tobelem, 1994, The Biochemical journal.

Effects of a new platelet glycoprotein IIb/IIIa antagonist, SR121566, on platelet activation, platelet‐leukocyte interaction and thrombin generation

J. Herbert, J. Hérault, P. Savi, 1998, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Effect of SR121566A, a Potent GP IIb-IIIa Antagonist on Platelet-mediated Thrombin Generation In Vitro and In Vivo

J. Herbert, J. Hérault, P. Savi, 1998, Thrombosis and Haemostasis.

Activation of human vascular endothelial cells by factor Xa: effect of specific inhibitors.

J. Herbert, J. Hérault, F. Bono, 1999, Biochemical pharmacology.

Clopidogrel and antiplatelet therapy

J. Herbert, 1994 .

Potentiating effects of anticoagulants and antiplatelet agents on streptokinase-induced thrombolysis in the rabbit

J. Herbert, J. Maffrand, A. Bernat, 1993 .

Clopidogrel, A Novel Antiplatelet and Antithrombotic Agent

J. Herbert, J. Maffrand, J. Necciari, 1993 .

Effect of SR 33805 on arterial smooth muscle cell proliferation and neointima formation following vascular injury.

J. Herbert, P. Chatelain, P. Schaeffer, 1995, European journal of pharmacology.

Long-term blockade of angiotensin AT1 receptors increases survival of obese Zucker rats.

J. Herbert, P. Bruneval, B. Poirier, 2006, European journal of pharmacology.

SR 90107A/Org 31540, a Novel Anti‐Factor Xa Antithrombotic Agent

J. Herbert, P. Zandberg, J. Necciari, 1997 .

Hirudin ameliorates intestinal radiation toxicity in the rat: support for thrombin inhibition as strategy to minimize side‐effects after radiation therapy and as countermeasure against radiation exposure

L. Fink, J. Herbert, M. Hauer-Jensen, 2004, Journal of thrombosis and haemostasis : JTH.

Receptor-independent Role of Urokinase-Type Plasminogen Activator in Pericellular Plasmin and Matrix Metalloproteinase Proteolysis during Vascular Wound Healing in Mice

P. Carmeliet, L. Moons, D. Collen, 1998, The Journal of cell biology.

Involvement of u‐PA in the anti‐apoptotic activity of TGFβ for vascular smooth muscle cells

P. Carmeliet, J. Herbert, J. M. Herbert, 1997, FEBS letters.

Role of HIF-1 alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis (vol 394, pg 485, 1998)

P. Carmeliet, R. Jain, M. Neeman, 1998 .

Short-Term Inhibition of ADP-Induced Platelet Aggregation by Clopidogrel Ameliorates Radiation-Induced Toxicity in Rat Small Intestine

L. Fink, J. Herbert, M. Hauer-Jensen, 2002, Thrombosis and Haemostasis.

Experimental proof for the structure of a thrombin-inhibiting heparin molecule.

S. Pérez, J. Herbert, J. Hérault, 2001, Chemistry.

New synthetic heparin mimetics able to inhibit thrombin and factor Xa.

J. Herbert, J. Hérault, M. Petitou, 1999, Bioorganic & medicinal chemistry letters.

Tumor-promoting phorbol esters stimulate bovine cerebral cortex capillary endothelial cell growth in vitro.

J. Herbert, J. Maffrand, I. Daviet, 1989, Biochemical and biophysical research communications.

The mitogenic effect of H2O2 for vascular smooth muscle cells is mediated by an increase of the affinity of basic fibroblast growth factor for its receptor

J. Herbert, F. Bono, P. Savi, 1996, FEBS letters.

Synthesis and biological activity of a new anti-factor Xa pentasaccharide with a C-interglycosidic bond

J. Herbert, J. Mallet, M. Petitou, 1997 .

The antithrombotic efficacy of the GP IIb/IIIa antagonist SR121787 is potentiated by antithrombin-dependent factor Xa inhibition without an increase in the bleeding risk in the rabbit.

J. Herbert, P. Hoffmann, P. Savi, 1999, Journal of cardiovascular pharmacology.

The synthetic pentasaccharide SR 90107A/org 31540 enhances tissue-type plasminogen activator-induced thrombolysis in rabbits

J. Herbert, P. Hoffmann, A. Bernat, 1996 .

The Antiaggregating and Antithrombotic Activity of Ticlopidine Is Potentiated by Aspirin in the Rat

J. Herbert, J. Maffrand, A. Bernat, 1996, Thrombosis and Haemostasis.

Effect of heparin on the angiogenic potency of basic and acidic fibroblast growth factors in the rabbit cornea assay.

J. Herbert, J. Maffrand, M. Laplace, 1988, International journal of tissue reactions.

The Lectin-like Domain of Thrombomodulin Confers Protection from Neutrophil-mediated Tissue Damage by Suppressing Adhesion Molecule Expression via Nuclear Factor κB and Mitogen-activated Protein Kinase Pathways

P. Hellings, S. Pollefeyt, D. Collen, 2002, The Journal of experimental medicine.

Serotonin receptor blockade improves distal perfusion after lower limb ischemia in the fatty Zucker rat.

J. Michel, J. Herbert, P. Janiak, 2002, Cardiovascular research.

Absence of cross-reactivity of SR90107A/ORG31540 pentasaccharide with antibodies to heparin-PF4 complexes developed in heparin-induced thrombocytopenia.

J. Herbert, B. Tardy, J. Amiral, 1997, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

DX 9065A a novel, synthetic, selective and orally active inhibitor of factor Xa: in vitro and in vivo studies.

J. Herbert, J. Hérault, J. Lormeau, 1996, The Journal of pharmacology and experimental therapeutics.

Effect of SR58611A, a potent beta-3 adrenoceptor agonist, on cutaneous wound healing in diabetic and obese mice.

J. Herbert, L. Millet, M. Arnone, 2006, European journal of pharmacology.

Angiotensin AT1 Receptor Antagonist Irbesartan Decreases Lesion Size, Chemokine Expression, and Macrophage Accumulation in Apolipoprotein E‐Deficient Mice

J. Herbert, B. Staels, D. Nisato, 2001, Journal of cardiovascular pharmacology.

Blockade of cannabinoid CB1 receptors improves renal function, metabolic profile, and increased survival of obese Zucker rats.

J. Herbert, J. Maffrand, G. Le Fur, 2007, Kidney international.

Tumor Vasculature Is Regulated by FGF/FGFR Signaling‐Mediated Angiogenesis and Bone Marrow‐Derived Cell Recruitment: This Mechanism Is Inhibited by SSR128129E, the First Allosteric Antagonist of FGFRs

J. Herbert, F. Géronimi, F. Bono, 2015, Journal of cellular physiology.

SSR182289A enhances thrombolysis induced by fibrinolytic agents in rabbit models of venous and arterial thrombosis

J. Herbert, L. Millet, J. Lorrain, 2004, Journal of thrombosis and haemostasis : JTH.

V2 receptor antagonism of DDAVP-induced release of hemostasis factors in conscious dogs.

J. Herbert, C. Serradeil-Le Gal, P. Hoffmann, 1997, The Journal of pharmacology and experimental therapeutics.

Synthesis of Conformationally Locked Carbohydrates: A Skew-Boat Conformation of L-Iduronic Acid Governs the Antithrombotic Activity of Heparin.

J. Herbert, S. Das, J. Mallet, 2001, Angewandte Chemie.

Heparin interactions with cultured human vascular endothelial and smooth muscle cells: Incidence on vascular smooth muscle cell proliferation

J. Herbert, J. Maffrand, 1989, Journal of cellular physiology.

Reversal of multidrug resistance by calcium channel blocker SR33557 without photoaffinity labeling of P-glycoprotein.

G. Laurent, J. Herbert, T. Levade, 1991, The Journal of biological chemistry.

New insights into the pathological role of TNF-alpha in early cardiac dysfunction and subsequent heart failure after infarction in rats.

J. Herbert, T. Sulpice, F. Boucher, 2004, American journal of physiology. Heart and circulatory physiology.

Use of radiolabeled 2-methylthio-ADP to study P2Y receptors on platelets and cell lines.

J. Herbert, P. Savi, 2004, Methods in molecular biology.

Characterization of P2x1 purinoreceptors on rat platelets: effect of clopidogrel

J. Herbert, P. Savi, J. Bornia, 1997, British journal of haematology.

Clopidogrel: An Antithrombotic Drug Acting on the ADP-dependent Activation Pathway of Human Platelets

P. Nurden, J. Herbert, G. Kieffer, 1996 .

Characterization of specific binding sites for [3H]2-MeS-ADP on megakaryocytoblastic cell lines in culture.

J. Herbert, P. Savi, A. Troussard, 1994, Biochemical pharmacology.

Evidence for the existence of two different ADP-binding sites on rat platelets.

J. Herbert, P. Savi, M. Laplace, 1994, Thrombosis research.

Malformin-a1 inhibits the binding of interleukin-1β (il1β) and suppresses the expression of tissue factor in human endothelial cells and monocytes

J. Herbert, P. Savi, M. Laplace, 1994 .

Binding of [3H]SR 27417, a novel platelet-activating factor (PAF) receptor antagonist, to rabbit and human platelets and polymorphonuclear leukocytes.

J. Herbert, J. Maffrand, M. Laplace, 1993, Biochemical pharmacology.

Effect of SR 47436, a novel angiotensin II AT1 receptor antagonist, on human vascular smooth muscle cells in vitro.

J. Herbert, D. Nisato, P. Chatelain, 1994, European journal of pharmacology.

Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cells survival and migration Running title: Neuropilin-2 enhances VEGFR-2 cellular responses

G. Neufeld, J. Herbert, F. Bono, 2006 .

Effect of Factor Xa Inhibitors on the Platelet-derived Microparticles Procoagulant Activity In Vitro> and In Vivo in Rats

J. Herbert, J. Hérault, A. Bernat, 2000, Thrombosis and Haemostasis.

SAR216471, an alternative to the use of currently available P2Y₁₂ receptor inhibitors?

J. Herbert, L. Millet, F. Bono, 2014, Thrombosis research.

Oligosaccharides corresponding to the regular sequence of heparin: chemical synthesis and interaction with FGF-2.

J. Herbert, J. Mallet, F. Bono, 1999, Bioorganic & medicinal chemistry.

First Synthetic Carbohydrates with the Full Anticoagulant Properties of Heparin.

J. Herbert, C. V. van Boeckel, M. Petitou, 1998, Angewandte Chemie.

AT1 Receptor Blockade Prevents Cardiac Dysfunction after Myocardial Infarction in Rats

S. Tanguy, J. Herbert, T. Sulpice, 2005, Cardiovascular Drugs and Therapy.

Biochemical and pharmacological properties of SANORG 34006, a potent and long-acting synthetic pentasaccharide.

J. Herbert, J. Hérault, P. Hoffmann, 1998, Blood.

O-acylated heparin derivatives with low anticoagulant activity decrease proliferation and increase alpha-smooth muscle actin expression in cultured arterial smooth muscle cells.

A. Desmoulière, G. Gabbiani, J. Herbert, 1992, European journal of pharmacology.

Urokinase and Tissue-type Plasminogen Activator Are Required for the Mitogenic and Chemotactic Effects of Bovine Fibroblast Growth Factor and Platelet-derived Growth Factor-BB for Vascular Smooth Muscle Cells*

P. Carmeliet, J. Herbert, I. Lamarche, 1997, The Journal of Biological Chemistry.

Effect of fantofarone, a new Ca2+ channel antagonist, on angioplasty-induced vasospasm in an atherosclerotic rabbit model.

J. Herbert, B. Dongay, F. Dol-Gleizes, 1998, Biochemical pharmacology.

Involvement of nitric oxide in amiodarone- and dronedarone-induced coronary vasodilation in guinea pig heart.

J. Herbert, D. Nisato, P. Gautier, 2004, European journal of pharmacology.

Pharmacological Characterization of SAR407899, a Novel Rho-Kinase Inhibitor

A. Kannt, J. Herbert, H. Ruetten, 2009, Hypertension.

Characterization of rat aortic smooth muscle cells resistant to the antiproliferative activity of heparin following long‐term heparin treatment

A. Desmoulière, J. Herbert, M. Pascal, 1994, Journal of cellular physiology.

The Synthetic Pentasaccharide Fondaparinux: First in the Class of Antithrombotic Agents that Selectively Inhibit Coagulation Factor Xa

J. Herbert, J. Necciari, M. Petitou, 2002, Seminars in thrombosis and hemostasis.

Antithrombin-mediated inhibition of factor VIIa-tissue factor complex by the synthetic pentasaccharide representing the heparin binding site to antithrombin.

J. Herbert, J. Hérault, J. Lormeau, 1996, Thrombosis and haemostasis.

Heterodimerization with vascular endothelial growth factor receptor-2 (VEGFR-2) is necessary for VEGFR-3 activity.

P. Carmeliet, J. Herbert, B. Ruggeri, 2004, Biochemical and biophysical research communications.

Clopidogrel: a review of its mechanism of action.

P. Nurden, J. Herbert, A. Nurden, 1998, Platelets.

Antithrombotic Properties of SSR182289A, a New, Orally Active Thrombin Inhibitor

J. Herbert, L. Millet, J. Lorrain, 2003, Journal of Pharmacology and Experimental Therapeutics.

Aprotinin reduces clopidogrel-induced prolongation of the bleeding time in the rat.

J. Herbert, J. Maffrand, A. Bernat, 1993, Thrombosis research.

Effect of SR 27417 on oedema formation induced in rabbit skin by platelet-activating factor or antigen.

J. Herbert, J. Maffrand, A. Bernat, 1992, European journal of pharmacology.

Ex vivo effects of SR 27417, a novel PAF antagonist, on rabbit platelet aggregation and [3H]-PAF binding.

J. Herbert, J. Maffrand, M. Laplace, 1992, Journal of lipid mediators.

Biochemical and pharmacological activities of SR 27417, a highly potent, long-acting platelet-activating factor receptor antagonist.

J. Herbert, J. Maffrand, G. Le Fur, 1991, The Journal of pharmacology and experimental therapeutics.

Protamine sulphate inhibits pentasaccharide (SR80027)-induced bleeding without affecting its antithrombotic and anti-factor Xa activity in the rat.

J. Herbert, A. Bernat, 1996, Haemostasis.

Platelet-activating Factor Induces NF-κB Activation through a G Protein-coupled Pathway (*)

Jiahuai Han, R. Ulevitch, V. Kravchenko, 1995, The Journal of Biological Chemistry.

Effect of SR 27417 on the binding of [3H]PAF to rabbit and human platelets and human polymorphonuclear leukocytes.

J. Herbert, J. Maffrand, C. Cailleau, 1993, Journal of lipid mediators.

Protective effect of SR 27417, a novel PAF antagonist, on lethal anaphylactic and endotoxin-induced shock in mice.

J. Herbert, J. Maffrand, L. Lespy, 1991, European journal of pharmacology.

Effect of SR 27417, a novel PAF antagonist on antigen-induced hypotension in the rat.

J. Herbert, A. Bernat, E. Tibirica, 1997, Journal of lipid mediators and cell signalling.

Loss of placental growth factor protects mice against vascular permeability in pathological conditions.

A. Luttun, P. Carmeliet, L. Moons, 2002, Biochemical and biophysical research communications.

Pharmacological evidence for the putative existence of two different subtypes of PAF receptors on platelets and leukocytes; studies with yangambin.

J. Herbert, H. Castro-Faria-Neto, J. Barbosa-Filho, 1997, Journal of lipid mediators and cell signalling.

Serotonin aggravates exercise-induced cardiac ischemia in the dog: effect of serotonin receptor antagonists.

B. Dubreuil, J. Herbert, P. Janiak, 2004, European journal of pharmacology.

Effect of SR 140333, a selective NK1 antagonist, on antigen-induced oedema formation in rat skin.

J. Herbert, A. Bernat, 1996, Journal of lipid mediators and cell signalling.

Importance of platelet activating factor in anaphylaxis-induced t-PA and PAI-1 increase in the rabbit

J. Herbert, A. Bernat, A. Dumas, 1995 .

Gi‐dependent and ‐independent mechanisms downstream of the P2Y12 ADP‐receptor

J. Herbert, B. Payrastre, P. Pacaud, 2004, Journal of thrombosis and haemostasis : JTH.

cAMP is not an important messenger for ADP-induced platelet aggregation.

J. Herbert, P. Savi, A. Pflieger, 1996, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Antiplatelet and antithrombotic efficacy of SR 121787, a nonpeptide orally active GP IIb/IIIa antagonist, in rabbits: comparison with clopidogrel and aspirin.

J. Herbert, P. Hoffmann, P. Savi, 1997, Journal of cardiovascular pharmacology.

Failure of heparin to inhibit the expression of the thrombin receptor following endothelial injury of the rabbit carotid artery.

J. Herbert, A. -. Guitteny, 1997, European journal of pharmacology.

Aurin tricarboxylic acid inhibits experimental venous thrombosis.

J. Herbert, A. Bernat, A. Lalé, 1994, Thrombosis research.

FcγRIIA requires a Gi-dependent pathway for an efficient stimulation of phosphoinositide 3-kinase, calcium mobilization, and platelet aggregation

J. Herbert, B. Payrastre, M. Plantavid, 2000 .

Role of P2Y1 purinoceptor in ADP‐induced platelet activation

M. Kaghad, J. Herbert, P. Savi, 1998, FEBS letters.

correction: Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

P. Carmeliet, R. Jain, M. Neeman, 1998, Nature.

Effect of fondaparinux on platelet activation in the presence of heparin-dependent antibodies: a blinded comparative multicenter study with unfractionated heparin.

J. Kelton, J. Herbert, Y. Gruel, 2005, Blood.

Deficiency of survivin in transgenic mice exacerbates Fas-induced apoptosis via mitochondrial pathways.

S. Pollefeyt, D. Collen, J. Herbert, 2002, Gastroenterology.

Determination of the anti-factor Xa activity of the synthetic pentasaccharide SR 90107A/ORG 31540 and of two structural analogues.

J. Herbert, J. Hérault, J. Lormeau, 1997, Thrombosis research.

Clopidogrel-induced qualitative changes in thrombus formation correlate with stent patency in injured pig cervical arteries.

M. Bonneau, J. Herbert, M. Wassef, 2002, Thrombosis research.

Efficacy of pentasaccharide in a dog model of hemodialysis.

T. Ing, J. Herbert, D. Hoppensteadt, 1997, Thrombosis research.

Altered intracellular distribution of daunorubicin in immature acute myeloid leukemia cells

G. Laurent, J. Herbert, C. Demur, 1997, International journal of cancer.

Laboratory monitoring of pentasaccharide in a dog model of hemodialysis.

T. Ing, J. Herbert, D. Hoppensteadt, 1999, Thrombosis research.

Effect of aspirin on platelet desaggregation induced by SR121566, a potent GP-IIb/IIIa antagonist.

J. Herbert, P. Savi, A. Bernat, 2000, Platelets.

Effect of SR121566A, a Potent GP IIb-IIIa Antagonist, on the HIT Serum/heparin-Induced Platelet Mediated Activation of Human Endothelial Cells

J. Herbert, P. Savi, W. Jeske, 1998, Thrombosis and Haemostasis.

Reversible biotinylated oligosaccharides: a new approach for a better management of anticoagulant therapy

J. Herbert, L. Millet, J. Hérault, 2008, Journal of thrombosis and haemostasis : JTH.

Activity of a synthetic hexadecasaccharide (SanOrg123781A) in a pig model of arterial thrombosis 1

M. Bonneau, J. Herbert, J. Hérault, 2004, Journal of thrombosis and haemostasis : JTH.

Comparative effects of two synthetic oligosaccharides on platelet activation induced by plasma from HIT patients

J. Herbert, J. Hérault, P. Savi, 2003, Journal of thrombosis and haemostasis : JTH.

Pharmacokinetics of New Synthetic Heparin Mimetics

J. Herbert, J. Hérault, F. Bono, 2002, Thrombosis and Haemostasis.

Synthesis and pharmacological properties of a close analogue of an antithrombotic pentasaccharide (SR 90107A/ORG 31540).

J. Herbert, J. Hérault, M. Petitou, 1997, Journal of medicinal chemistry.

Lack of Plasminogen Activator Inhibitor-1 Promotes Growth and Abnormal Matrix Remodeling of Advanced Atherosclerotic Plaques in Apolipoprotein E–Deficient Mice

A. Luttun, P. Carmeliet, P. Tipping, 2002, Arteriosclerosis, thrombosis, and vascular biology.

Antagonism of SR 90107A/Org 31540-lnduced Bleeding by Protamine Sulfate in Rats and Mice

J. Herbert, P. Hoffmann, A. Bernat, 1996, Thrombosis and Haemostasis.

Accelerating ability of synthetic oligosaccharides on antithrombin inhibition of proteinases of the clotting and fibrinolytic systems Comparison with heparin and low-molecular-weight heparin

S. Olson, J. Herbert, I. Björk, 2004, Thrombosis and Haemostasis.

The Structure of Synthetic Oligosaccharides in Relation to Factor IXa Inhibition

J. Herbert, J. Hérault, F. Bono, 2002, Thrombosis and Haemostasis.

Life-Threatening Thrombosis in Mice With Targeted Arg48-to-Cys Mutation of the Heparin-Binding Domain of Antithrombin

P. Carmeliet, L. Moons, D. Collen, 2003, Circulation research.

The synthetic pentasaccharide SR 90107A/Org 31540 does not release lipase activity into the plasma.

J. Herbert, J. Hérault, P. Hoffmann, 1997, Thrombosis research.

Importance of platelets in the process leading to PAI-1 increase following endotoxaemia in vivo

J. Herbert, A. Bernat, A. Dumas, 1995 .

Polyunsaturated fatty acids reduce pyrogen-induced tissue factor expression in human monocytes.

J. Herbert, A. Lalé, A. Lalé, 1994, Biochemical pharmacology.

A unique trisaccharide sequence in heparin mediates the early step of antithrombin III activation.

J. Herbert, J. Hérault, M. Petitou, 1997, Glycobiology.

Synthesis of new conformationally constrained pentasaccharides as molecular probes to investigate the biological activity of heparin.

J. Herbert, J. Mallet, M. Petitou, 2003, Biochimie.

Identification of a hexasaccharide sequence able to inhibit thrombin and suitable for 'polymerisation'.

J. Herbert, M. Petitou, P. Duchaussoy, 1999, Carbohydrate research.

Assessment through chemical synthesis of the size of the heparin sequence involved in thrombin inhibition.

J. Herbert, M. Petitou, M. Ceccato, 1999, Carbohydrate research.

Synthetic oligosaccharides having various functional domains: potent and potentially safe heparin mimetics.

J. Herbert, J. Hérault, M. Petitou, 1999, Bioorganic & medicinal chemistry letters.

Introducing a C-interglycosidic bond in a biologically active pentasaccharide hardly affects its biological properties.

J. Herbert, J. Hérault, J. Mallet, 1998, Bioorganic & medicinal chemistry.

Synthesis and anti-thrombin activity of a hexasaccharide corresponding to the binding site of dermatan sulfate to heparin cofactor II

J. Herbert, J. Hérault, J. Mallet, 1997 .

The NK1 receptor is involved in the neurokinin‐induced shape change of rabbit platelets

J. Herbert, G. Le Fur, P. Savi, 1992, FEBS letters.

Purification and characterization of a novel protease from culture filtrates of a Streptomyces sp.

M. Maftouh, J. Herbert, J. Maffrand, 1996, FEMS microbiology letters.

Importance of the phenotypic state of vascular smooth muscle cells on the binding and the mitogenic activity of endothelin

C. S. Gal, J. Herbert, J. Maffrand, 1991, Peptides.

A synthetic heparin/heparan sulfate-like decasaccharide releases lipase activity in vivo. Chemical synthesis and biological activity

J. Herbert, P. Hoffmann, M. Petitou, 1997 .

IL‐4 and IL‐13 exhibit comparable abilities to reduce pyrogen‐induced expression of procoagulant activity in endothelial cells and monocytes

A. Minty, J. Herbert, P. Savi, 1993, FEBS Letters.

Regulator of G-Protein Signaling 18 Controls Both Platelet Generation and Function

T. Sorg, J. Herbert, C. Pendaries, 2014, PloS one.

Effect of pentosan polysulphate, standard heparin and related compounds on protein kinase C activity.

J. Herbert, J. Maffrand, 1991, Biochimica et biophysica acta.

SR146131: a new potent, orally active, and selective nonpeptide cholecystokinin subtype 1 receptor agonist. I. In vitro studies.

P. Soubrié, D. Gully, R. Boigegrain, 1999, The Journal of pharmacology and experimental therapeutics.

Effects of SanOrg123781A, a synthetic heparin mimetic, in a mouse model of electrically induced carotid artery injury: synergism with the antiplatelet agent clopidogrel.

J. Herbert, R. Masson, J. Lorrain, 2003 .

Fc g RIIA requires a Gi-dependent pathway for an efﬁcient stimulation of phosphoinositide 3-kinase, calcium mobilization, and platelet aggregation

J. Herbert, B. Payrastre, M. Plantavid, 2000 .

Platelet-activating factor (PAF) is not an essential component of the cascade leading to smooth muscle cell proliferation following vascular injury.

J. Herbert, M. Laplace, A. Marés, 1995, Journal of lipid mediators and cell signalling.

Remodeling of Advanced Atherosclerotic Plaques in Apolipoprotein E Lack of Plasminogen Activator Inhibitor-1 Promotes Growth and Abnormal Matrix

A. Luttun, Peter Crawley, P. Tipping, 2002 .

Targeted deletion of the cytosolic domain of tissue factor in mice does not affect development.

P. Carmeliet, L. Moons, D. Collen, 2001, Biochemical and biophysical research communications.

Modulation of platelet function and vascular smooth muscle contractile actions by a novel, selective, highly potent 5-HT2 antagonist (SR46349).

J. Herbert, D. Callas, J. Fareed, 1996, Thrombosis research.

IL‐4 inhibits LPS‐, IL‐1β‐ and TNFα‐induced expression of tissue factor in endothelial cells and monocytes

J. Herbert, P. Savi, M. Laplace, 1992 .

Relaxant effect of 2-methyl-thio-adenosine diphosphate on rat thoracic aorta: effect of clopidogrel.

J. Herbert, P. Savi, F. Dol-Gleizes, 1999, European journal of pharmacology.

Physico-Chemical Characterization and Pharmacological Properties of Different Cyclodextrin Complexes of a Platelet Activating Factor Receptor Antagonist: SR 27417A.

R. Ghirlando, J. Herbert, B. Perly, 1999 .

Hypoxia primes endotoxin‐induced tissue factor expression in human monocytes and endothelial cells by a PAF‐dependent mechanism

J. Herbert, D. Corseaux, A. Bernat, 1996, Journal of cellular physiology.

Effect of various drugs on adriamycin-enhanced venous thrombosis in the rat: importance of PAF.

J. Herbert, A. Bernat, 1994, Thrombosis research.

Induction of vascular smooth muscle cell growth by selective activation of the thrombin receptor Effect of heparin

J. Herbert, I. Lamarche, F. Dol, 1992, FEBS letters.

SSR182289A, a Novel, Orally Active Thrombin Inhibitor: In Vitro Profile and ex Vivo Anticoagulant Activity

J. Herbert, G. Lassalle, F. Guilbert, 2002, Journal of Pharmacology and Experimental Therapeutics.

Importance of platelets in experimental venous thrombosis in the rat.

J. Herbert, J. Maffrand, A. Bernat, 1992, Blood.

In Vivo and In Vitro Antiarrhythmic Effects of SSR149744C in Animal Models of Atrial Fibrillation and Ventricular Arrhythmias

J. Herbert, D. Nisato, P. Gautier, 2005, Journal of cardiovascular pharmacology.

A role for thrombin in liver fibrosis

I. Laurendeau, A. Desmoulière, J. Herbert, 2004, Gut.

Protective effect of SR 27417, a novel PAF antagonist, on PAF- or endotoxin-induced hypotension in the rat and the guinea-pig.

J. Herbert, J. Maffrand, A. Bernat, 1992, Journal of lipid mediators.

Synthesis of Conformationally Locked L-Iduronic Acid Derivatives. Direct Evidence for a Critical Role of the Skew-Boat 2S0 Conformer in the Activation of Antithrombin by Heparin.

J. Herbert, S. Das, J. Mallet, 2002 .

Pharmacokinetic study of three synthetic AT‐binding pentasaccharides in various animal species‐extrapolation to humans

J. Herbert, J. Hérault, J. Lormeau, 1997, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

SR123781A, a Synthetic Heparin Mimetic

J. Herbert, J. Hérault, P. Savi, 2001, Thrombosis and Haemostasis.

First Synthetic Carbohydrates with the Full Anticoagulant Properties of Heparin.

J. Herbert, C. V. van Boeckel, M. Petitou, 1998, Angewandte Chemie.

SSR182289A, a selective and potent orally active thrombin inhibitor.

J. Herbert, Z. Bocskei, J. Lorrain, 2004, Bioorganic & medicinal chemistry.

SR142948A is a potent antagonist of the cardiovascular effects of neurotensin.

J. Herbert, P. Schaeffer, A. Bernat, 1998, Journal of cardiovascular pharmacology.

Neurotensin induces the release of prostacyclin from human umbilical vein endothelial cells in vitro and increases plasma prostacyclin levels in the rat.

J. Herbert, P. Schaeffer, A. Bernat, 1997, European journal of pharmacology.

Effector protease receptor 1 mediates the mitogenic activity of factor Xa for vascular smooth muscle cells in vitro and in vivo.

J. Herbert, J. Hérault, F. Bono, 1998, The Journal of clinical investigation.

Comparative effects of two direct and indirect factor Xa inhibitors on free and clot-bound prothrombinase.

J. Herbert, J. Hérault, J. Lormeau, 1997, The Journal of pharmacology and experimental therapeutics.

Inhibitory effect of clopidogrel on platelet adhesion and intimal proliferation after arterial injury in rabbits.

J. Herbert, J. Maffrand, J P Maffrand, 1993, Arteriosclerosis and thrombosis : a journal of vascular biology.

Loss or inhibition of uPA or MMP-9 attenuates LV remodeling and dysfunction after acute pressure overload in mice.

P. Carmeliet, S. Heymans, L. Moons, 2005, The American journal of pathology.

Chelerythrine, a selective protein kinase C inhibitor, counteracts pyrogen-induced expression of tissue factor without effect on thrombomodulin down-regulation in endothelial cells.

J. Herbert, P. Savi, M. Laplace, 1993, Thrombosis Research.

Effects of Heparin and Related Sulfated Polysaccharides on Tissue Factor Expression Induced by Mitogenic and Non-mitogenic Factors in Human Vascular Smooth Muscle Cells

J. Herbert, B. Boneu, J. Xuereb, 1999, Thrombosis and Haemostasis.

Effects of SanOrg123781A, a Synthetic Hexadecasaccharide, in a Mouse Model of Electrically Induced Carotid Artery Injury: Synergism with the Antiplatelet Agent Clopidogrel

N. Roome, J. Herbert, R. Masson, 2004, Journal of Pharmacology and Experimental Therapeutics.

Involvement of protein kinase C in the mitogenic and chemotaxis effects of basic fibroblast growth factor on bovine cerebral cortex capillary endothelial cells

J. Herbert, J. Maffrand, I. Daviet, 1990, FEBS letters.

Specific impairment of human platelet P2Y(AC) ADP receptor-mediated signaling by the antiplatelet drug clopidogrel.

U. Walter, J. Geiger, J. Herbert, 1999, Arteriosclerosis, thrombosis, and vascular biology.

New orally active non-peptide fibrinogen receptor (GpIIb-IIIa) antagonists: identification of ethyl 3-[N-[4-[4-[amino[(ethoxycarbonyl) imino]methyl]phenyl]-1,3-thiazol-2-yl]-N-[1-[(ethoxycarbonyl)methyl]pip erid -4-yl]amino]propionate (SR 121787) as a potent and long-acting antithrombotic agent.

J. Herbert, J. Maffrand, P. Savi, 1997, Journal of medicinal chemistry.

Biochemical and Pharmacological Properties of SR 33805, a Novel Ca2+ Channel Antagonist

J. Herbert, P. Chatelain, A. Manning, 1995 .

N-[6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1H-indole-3-carboxamide (SAR216471), a novel intravenous and oral, reversible, and directly acting P2Y12 antagonist.

J. Herbert, N. Delesque, L. Millet, 2014, Journal of medicinal chemistry.

SR 27417, a highly potent, selective and long-acting antagonist of the PAF receptor

G. Fur, J. Herbert, J. Maffrand, 1992 .

216471 ) , a Novel Intravenous and Oral , Reversible , and Directly Acting P 2 Y 12 Antagonist

J. Herbert, N. Delesque, L. Millet, 2014 .

Verbascoside isolated from Lantana camara, an inhibitor of protein kinase C.

J. Herbert, J. Augereau, J. Gleye, 1991, Journal of natural products.

Structure and stereochemistry of the active metabolite of clopidogrel.

M. Maftouh, J. Herbert, J. Maffrand, 2002, Drug metabolism and disposition: the biological fate of chemicals.

VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis

K. Becker, Yihai Cao, E. Wawrousek, 2009, Proceedings of the National Academy of Sciences.

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1

A. Luttun, P. Carmeliet, H. Dvorak, 2002, Nature Medicine.

An inherited bleeding disorder linked to a defective interaction between ADP and its receptor on platelets. Its influence on glycoprotein IIb-IIIa complex function.

P. Nurden, J. Herbert, J. Maffrand, 1995, The Journal of clinical investigation.

Hypoxia-inducible Factor-2α (HIF-2α) Is Involved in the Apoptotic Response to Hypoglycemia but Not to Hypoxia*

P. Carmeliet, Y. Dor, D. Collen, 2001, The Journal of Biological Chemistry.

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration

Till Acker, Can Ince, Lieve Moons, 2001, Nature Genetics.

Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure

A. Luttun, P. Carmeliet, S. Heymans, 1999, Nature Medicine.

Targeted Deficiency or Cytosolic Truncation of the VE-cadherin Gene in Mice Impairs VEGF-Mediated Endothelial Survival and Angiogenesis

P. Carmeliet, M. Lampugnani, L. Moons, 1999, Cell.

Compound screening platform using human induced pluripotent stem cells to identify small molecules that promote chondrogenesis

P. Wright, J. Herbert, P. August, 2012, Protein & Cell.

Interspecies comparison of the antiplatelet, antithrombotic, and hemorrhagic effects of SR 121566A, a novel nonpeptide GP IIb/IIIa antagonist.

J. Herbert, P. Hoffmann, P. Savi, 1999, Journal of cardiovascular pharmacology.

Lesion Progression in apoE-Deficient Mice: Implication of Chemokines and Effect of the AT1 Angiotensin II Receptor Antagonist Irbesartan

J. Herbert, D. Hum, B. Staels, 2004, Journal of cardiovascular pharmacology.

Effect of ciprofibrate on fibrinogen synthesis in vitro on hepatoma cells and in vivo in genetically obese Zucker rats.

J. Herbert, A. Bernat, L. Chatenêt-Duchêne, 1999, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Characterization of specific binding sites for [3H]-staurosporine on various protein kinases.

J. Herbert, J. Maffrand, J P Maffrand, 1990, Biochemical and biophysical research communications.

Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1

Christoph Dehio, Danica Stanimirovic, Lieve Moons, 2003, Nature Medicine.

Genetic evidence for a tumor suppressor role of HIF-2alpha.

P. Carmeliet, R. Jain, T. Acker, 2005, Cancer cell.

Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties.

Jie Zhang, Harald Schwalbe, Francesco Luigi Gervasio, 2013, Cancer cell.

Conversion of human fibroblasts into angioblast-like multipotent progenitor cells

F. Gage, I. Sancho-Martinez, L. Laurent, 2012, Nature Methods.

Use of agonists of beta 3-adrenergic receptors for the preparation of healing drugs

J. Herbert, M. Arnone, A. Bernat, 1997 .

Human Umbilical Vein Endothelial Cells Express High Affinity Neurotensin Receptors Coupled to Intracellular Calcium Release (*)

J. Herbert, P. Savi, P. Schaeffer, 1995, Journal of Biological Chemistry.

Antiplatelet and Antithrombotic Activity of SL65.0472, a Mixed 5-HT1B/5-HT2A Receptor Antagonist

J. Herbert, P. Savi, P. Janiak, 2001, Thrombosis and Haemostasis.

Biochemical and pharmacological properties of clopidogrel : a new ADP receptor antagonist

J. Herbert, J. Maffrand, P. Savi, 1999 .

The Antiaggregating and Antithrombotic Activity of Clopidogrel Is Potentiated by Aspirin in Several Experimental Models in the Rabbit

R. Falotico, J. Herbert, P. Savi, 1998, Thrombosis and Haemostasis.

Antithrombotic Activity of SR 46349, a Novel, Potent and Selective 5-HT2 Receptor Antagonist

J. Herbert, A. Bernat, F. Dol, 1993, Thrombosis and Haemostasis.

SR 121787, a New Orally Active Fibrinogen Receptor Antagonist

J. Herbert, J. Maffrand, P. Hoffmann, 1998, Thrombosis and Haemostasis.

Effect of Various Antiplatelet Agents on Acute Arterial Thrombosis in the Rat

J. Herbert, J. Maffrand, A. Bernat, 1993, Thrombosis and Haemostasis.

Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling.

T. Blundell, P. Carmeliet, K. Saxena, 2013, Cancer cell.

Functional cooperation between TrkA and p75(NTR) accelerates neuronal differentiation by increased transcription of GAP-43 and p21(CIP/WAF) genes via ERK1/2 and AP-1 activities.

G. Perini, J. Herbert, S. Trazzi, 2007, Experimental cell research.

Inhibition of vascular smooth muscle cell proliferation in culture by pentosan polysulphate and related compounds.

J. Herbert, J. Maffrand, J. Gordon, 1987, Thrombosis research.

Circannual variations of the bleeding time in the rat.

J. Herbert, J. Maffrand, A. Bernat, 1993, Chronobiology international.

Gas6 deficiency in recipient mice of allogeneic transplantation alleviates hepatic graft-versus-host disease.

P. Carmeliet, J. Herbert, F. Bono, 2010, Blood.

Gas 6 deficiency in recipient mice of allogeneic transplantation alleviates hepatic graft-versus-host disease

P. Carmeliet, J. Herbert, F. Bono, 2010 .

Clinical evidence for anti-inflammatory effects of antiplatelet therapy in patients with atherothrombotic disease

Deepak L. Bhatt, S. Steinhubl, T. Lüscher, 2007, Vascular medicine.

Urokinase mediates bFGF-induced vascular smooth muscle cell migration under the control of TGFβ

P. Carmeliet, J. Herbert, 1998 .

Human umbilical vein endothelial cells express high affinity receptors for factor Xa

J. Herbert, F. Bono, J. Lormeau, 1997, Journal of cellular physiology.

Contribution of Erythrocytes to Thrombin Generation in Whole Blood

J. Herbert, J. Hérault, J. Lormeau, 1999, Thrombosis and Haemostasis.

Echinomycin Suppresses the Pyrogenic Effects of Endotoxin and Interleukin- lβ in Human Endothelial Cells and Peripheral Blood Mononuclear Cells

P. Casellas, J. Herbert, J. Derocq, 1996, Thrombosis and Haemostasis.

Characterization of extracellular binding sites for [3H]-staurosporine on capillary endothelial cells.

J. Herbert, J. Maffrand, I. Daviet, 1991, Cell biology international reports.

Tumor cell adherence to cultured capillary endothelial cells is promoted by activators of protein kinase C.

J. Herbert, J. Maffrand, 1991, Biochemical pharmacology.

Induction of Endothelial Cell Adhesion Molecules by Serum and Immunoglobulins G from a Patient with Vasculitis and Monoclonal Gammapathy: Potential Relevance to Vasculitis

J. Herbert, I. Quéré, G. Tobelem, 1998, Thrombosis and Haemostasis.

Vascular endothelial growth factor production by fibroblasts in response to factor VIIa binding to tissue factor involves thrombin and factor Xa.

J. Herbert, V. Ollivier, J. Hakim, 2000, Arteriosclerosis, thrombosis, and vascular biology.

Coagulation factor Xa induces endothelium-dependent relaxations in rat aorta.

J. Herbert, F. Bono, P. Schaeffer, 1997, Circulation research.

SR 25989 inhibits healing of a mechanical wound of confluent human saphenous vein endothelial cells which is modulated by standard heparin and growth factors

J. Herbert, J. Maffrand, J. Cazenave, 1994, Journal of cellular physiology.

endothelial cells, platelets and leukocytes GAS6 promotes inflammation by enhancing interactions between

P. Carmeliet, B. Dahlbäck, L. Moons, 2013 .

Protein kinase C: a key factor in the regulation of tumor cell adhesion to the endothelium.

J. Herbert, Jean-Marc Herbert, 1993, Biochemical pharmacology.

Identification and Biological Activity of the Active Metabolite of Clopidogrel

J. Herbert, J. Maffrand, M. Pascal, 2000, Thrombosis and Haemostasis.

Involvement of peripheral benzodiazepine receptor in the oxidative stress, death-signaling pathways, and renal injury induced by ischemia-reperfusion.

O. Kunduzova, J. Herbert, R. Salvayre, 2004, Journal of the American Society of Nephrology : JASN.

Hypercholesterolemia does not affect the antiplatelet activity of clopidogrel.

J. Herbert, P. Savi, A. Bernat, 1995, Platelets.

The Antiaggregating Activity of Clopidogrel Is due to a Metabolic Activation by the Hepatic Cytochrome P450-1A

J. Herbert, J. Maffrand, P. Savi, 1994, Thrombosis and Haemostasis.

Protein Kinase C α Expression Is Required for Heparin Inhibition of Rat Smooth Muscle Cell Proliferation in Vitro and in Vivo*

A. Clowes, J. Herbert, M. Pascal, 1996, The Journal of Biological Chemistry.

Potentiating Effect of Clopidogrel and SR 46349, a Novel 5-HT2 Antagonist, on Streptokinase-Induced Thrombolysis in the Rabbit

J. Herbert, A. Bernat, F. Dol, 1993, Thrombosis and Haemostasis.

Effects of clopidogrel, aspirin and combined therapy in a porcine ex vivo model of high-shear induced stent thrombosis.

F Litvack, S. Kaul, P. Shah, 1998, European heart journal.

Effects of ADP-receptor antagonism beyond traditional inhibition of platelet aggregation

J. Herbert, 2004, Expert opinion on investigational drugs.

VEGF‐R2 and neuropilin‐1 are involved in VEGF‐A‐induced differentiation of human bone marrow progenitor cells

J. Herbert, N. Delesque, F. Bono, 2004, Journal of cellular physiology.

In Vivo and In Vitro Characterization of the Novel Antiarrhythmic Agent SSR149744C: Electrophysiological, Anti-Adrenergic, and Anti-Angiotensin II Effects

Patrick Gautier, J. Herbert, D. Nisato, 2004, Journal of cardiovascular pharmacology.

P2Y receptors: in the middle of the road.

J. Herbert, J. Boeynaems, D. Communi, 2000, Trends in pharmacological sciences.

CCK‐JMV‐180 acts as an antagonist of the CCKA receptor in the human IMR‐32 neuroblastoma cell line

J. Herbert, P. Schaeffer, V. Prabonnaud, 1994, FEBS letters.

Investigations with the selective PKC inhibitor chelerythrine on human basophils

J. Herbert, E. Stebut, H. Wolff, 1994, Agents and Actions.

P2y(12), a new platelet ADP receptor, target of clopidogrel.

J. Herbert, N. Delesque, P. Savi, 2001, Biochemical and biophysical research communications.

The antiaggregating activity of clopidogrel is not affected by N-acetyl L-cysteine

J. Herbert, P. Savi, A. Lalé, 2003, Thrombosis and Haemostasis.

IL-4 inhibits LPS-, IL-1 beta- and TNF alpha-induced expression of tissue factor in endothelial cells and monocytes.

J. Herbert, P. Savi, M. Laplace, 1992, FEBS letters.

P2Y12, A New Platelet ADP Receptor, Target of Clopidogrel

J. Herbert, P. Savi, 2003, Seminars in vascular medicine.

Importance of hepatic metabolism in the antiaggregating activity of the thienopyridine clopidogrel.

J. Herbert, J. Maffrand, P. Savi, 1992, Biochemical pharmacology.

The active metabolite of Clopidogrel disrupts P2Y12 receptor oligomers and partitions them out of lipid rafts.

Pascual Ferrara, Françoise Bono, P. Ferrara, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Ultrastructural studies of platelet aggregates from human subjects receiving clopidogrel and from a patient with an inherited defect of an ADP-dependent pathway of platelet activation.

M. Humbert, P. Nurden, J. Herbert, 1996, Arteriosclerosis, thrombosis, and vascular biology.

Biochemical and pharmacological properties of SANORG 32701. Comparison with the "synthetic pentasaccharide' (SR 90107/ORG 31540) and standard heparin.

J. Herbert, J. Hérault, M. Petitou, 1996, Circulation research.

Isolation of vascular smooth muscle cells from a single murine aorta.

Mark L. Benson, J. Herbert, M. Benson, 2001, Methods in cell science : an official journal of the Society for In Vitro Biology.

Anti-Thrombotic Effect of a Synthetic Heparin Mimetic in an Arterial Model of Thrombosis in Rats: Comparison with Unfractionated Heparin and Nadroparin

J. Herbert, P. Léger, J. Hérault, 2002, Thrombosis and Haemostasis.

Long‐term persistence of low‐molecular‐weight material with anti‐factor Xa activity contributes to anticoagulant and antithrombotic effects after subcutaneous injection of CY 216 in the rabbit

J. Herbert, J. Hérault, B. Boneu, 1997, Blood Coagulation and Fibrinolysis.

Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis.

J. Herbert, P. Savi, 2005, Seminars in thrombosis and hemostasis.

Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy.

P. Carmeliet, S. Goff, D. Collen, 2005, The Journal of clinical investigation.

Development of an experimental model of pre-thrombosis in rats based on Wessler's principle using a calibrated venous stasis

G. Leftheriotis, J. Herbert, P. Pottier, 2003, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Role of Peripheral Benzodiazepine Receptors in Mitochondrial, Cellular, and Cardiac Damage Induced by Oxidative Stress and Ischemia-Reperfusion

G. Fur, J. Herbert, T. Sulpice, 2003, Journal of Pharmacology and Experimental Therapeutics.

Peripheral benzodiazepine receptor agonists exhibit potent antiapoptotic activities.

J. Herbert, G. Le Fur, F. Bono, 1999, Biochemical and biophysical research communications.

Effect of SR-49059, a vasopressin V1a antagonist, on human vascular smooth muscle cells.

J. Herbert, G. Le Fur, P. Schaeffer, 1995, The American journal of physiology.

Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration.

G. Neufeld, J. Herbert, F. Bono, 2006, Blood.

A novel inhibitor of p75-neurotrophin receptor improves functional outcomes in two models of traumatic brain injury

Adam R Ferguson, G. Manley, M. Beattie, 2016, Brain : a journal of neurology.

P2Y receptor antagonists in thrombosis.

J. Herbert, J. Boeynaems, P. Savi, 2005, Current opinion in investigational drugs.

Compound screening platform using human induced pluripotent stem cells to identify small molecules that promote chondrogenesis

P. Wright, J. Herbert, P. August, 2012, Protein & Cell.

Tissue-type plasminogen activator is a potent mitogen for human aortic smooth muscle cells.

J. Herbert, T. Gauthier, V. Prabonnaud, 1994, The Journal of biological chemistry.

Author Correction: Conversion of human fibroblasts to angioblast-like progenitor cells

F. Gage, I. Sancho-Martinez, L. Laurent, 2020, Nature Methods.

Binding of [3H]-2-methylthio ADP to rat platelets--effect of clopidogrel and ticlopidine.

J. Herbert, J. Maffrand, P. Savi, 1994, The Journal of pharmacology and experimental therapeutics.

Targeted Identification of Sialoglycoproteins in Hypoxic Endothelial Cells and Validation in Zebrafish Reveal Roles for Proteins in Angiogenesis

P. Ferrara, G. Favre, J. Herbert, 2014, The Journal of Biological Chemistry.

Malformin-A1 inhibits the binding of interleukin-1 beta (IL1 beta) and suppresses the expression of tissue factor in human endothelial cells and monocytes.

J. Herbert, P. Savi, M. Laplace, 1994, Biochemical pharmacology.

78 Receptor-independent role of urokinase-type plasminogen activator during vascular wound healing in mice

P. Carmeliet, L. Moons, D. Collen, 1997 .

Tissue factor is not involved in the mitogenic activity of factor VIIa.

P. Carmeliet, J. Herbert, V. Ollivier, 2001, Biochemical and biophysical research communications.

ADP receptors on platelets and ADP‐selective antiaggregating agents

J. Herbert, P. Savi, 1996 .

Using 4-substituted tetrahydropyridines for manufacturing medicaments acting on the TGF-beta-1

J. Herbert, F. Bono, I. Lamarche, 1997 .

The inhibitory effect of heparin for vascular smooth muscle cell proliferation or migration is not mediated by u-PA and t-PA.

P. Carmeliet, J. Herbert, F. Bono, 1997, Thrombosis research.

Deletion of the hypoxia-response element in the VEGF promoter causes adult onset motor neuron degeneration

P. Carmeliet, B. Strooper, D. Lambrechts, 2002 .

Experimental and clinical pharmacology of pentosan polysulfate.

J. Herbert, J. Maffrand, P. Savi, 1991, Seminars in thrombosis and hemostasis.

FcgammaRIIA requires a Gi-dependent pathway for an efficient stimulation of phosphoinositide 3-kinase, calcium mobilization, and platelet aggregation.

J. Herbert, B. Payrastre, M. Plantavid, 2000, Blood.

Studies on the Binding of 3H-SR121566, an Inhibitor of Gp IIb-IIIa Activation

J. Herbert, P. Savi, G. Zamboni, 2001, Thrombosis and Haemostasis.

Clopidogrel is more effective than aspirin in inhibiting acute stent thrombosis

S. Kaul, J. Herbert, Masato Nakamura, 1996 .

Binding characteristics of SSR180575, a potent and selective peripheral benzodiazepine ligand.

J. Herbert, F. Bono, N. Leducq, 2003, Biochemical and biophysical research communications.

Effect of clopidogrel treatment on ADP‐induced phosphorylations in rat platelets

J. Herbert, J. Maclouf, P. Savi, 1997, British journal of haematology.

ADP Receptors on Platelets and ADP-Selective Antiaggregating Agents

J. Herbert, P. Savi, 1996 .

Experimental Studies on Guanosine 3’,5’-Cyclic Monophosphate Levels and Airway Responsiveness of the Novel Phosphodiesterase Type 5 Inhibitor

J. Herbert, M. Pascal, P. Schaeffer, 1999, Arzneimittelforschung.

Fibroblast growth factor signaling affects vascular outgrowth and is required for the maintenance of blood vessel integrity.

P. Carmeliet, A. Van Schepdael, M. Affolter, 2014, Chemistry & biology.

Characterisation of the effects of SR146131, a novel non-peptide CCK(1) receptor agonist, on IMR-32 human neuroblastoma cells.

J. Herbert, P. Schaeffer, M. Laplace, 2000, European journal of pharmacology.

Receptor-independent Role of Urokinase-Type Plasminogen Activator in Pericellular Plasmin and Matrix Metalloproteinase Proteolysis during Vascular Wound Healing in Mice

P. Carmeliet, L. Moons, D. Collen, 1998, The Journal of cell biology.

Biochemical and pharmacological activities of SR 26831, a potent and selective elastase inhibitor.

J. Herbert, J. Maffrand, G. Le Fur, 1992, The Journal of pharmacology and experimental therapeutics.

Clopidogrel and anti platelet therapy

J. Herbert, 1994 .

Investigation of the selectivity of thrombin-binding aptamers for thrombin titration in murine plasma.

J. Herbert, A. Gué, A. Bancaud, 2016, Biosensors & bioelectronics.

SSR69071, an elastase inhibitor, reduces myocardial infarct size following ischemia-reperfusion injury.

J. Herbert, P. Janiak, N. Duval, 2003, European journal of pharmacology.

Efficacy of pentasaccharide on a prethrombosis model based on a calibrated stasis by the increase in up-stream venous pressure

G. Leftheriotis, J. Herbert, N. Passuti, 2003, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Compositions for the treatment and prevention of arterial thrombosis and the use of a factor xa inhibitor alone and / or in combination with a platelet antiagrant

J. Herbert, M. Petitou, A. Bernat, 1997 .

Targeted Identification of Sialoglycoproteins in Hypoxic Endothelial Cells and Validation in Zebrafish Reveal Roles for Proteins in Angiogenesis

P. Ferrara, G. Favre, J. Herbert, 2014, The Journal of Biological Chemistry.

Low doses of endotoxin potentiate venous thrombosis in the rabbit.

J. Herbert, J. Maffrand, A. Bernat, 1994, Haemostasis.