E. Bremer

发表

Osmotic regulation of porin expression: a role for DNA supercoiling

C. Higgins, G. May, K. Graeme-Cook, 1989, Molecular microbiology.

Adaptation of Bacillus subtilis carbon core metabolism to simultaneous nutrient limitation and osmotic challenge: a multi-omics perspective.

M. Hecker, M. Lalk, C. Wittmann, 2014, Environmental microbiology.

Glycine betaine aldehyde dehydrogenase from Bacillus subtilis: characterization of an enzyme required for the synthesis of the osmoprotectant glycine betaine

J. Boch, E. Bremer, Gabriele Nau-Wagner, 1997, Archives of Microbiology.

Ectoine-Induced Proteins in Sinorhizobium meliloti Include an Ectoine ABC-Type Transporter Involved in Osmoprotection and Ectoine Catabolism

E. Bremer, M. Jebbar, L. Sohn-Bösser, 2005, Journal of bacteriology.

Osmotic Control of opuA Expression in Bacillus subtilis and Its Modulation in Response to Intracellular Glycine Betaine and Proline Pools

U. Völker, E. Bremer, L. Steil, 2012, Journal of bacteriology.

Feeding on compatible solutes: A substrate‐induced pathway for uptake and catabolism of ectoines and its genetic control by EnuR

J. Heider, J. E. Hallsworth, E. Bremer, 2017, Environmental microbiology.

Responses of Bacillus subtilis to Hypotonic Challenges: Physiological Contributions of Mechanosensitive Channels to Cellular Survival

E. Bremer, T. Hoffmann, C. Boiangiu, 2008, Applied and Environmental Microbiology.

Small cationic antimicrobial peptides delocalize peripheral membrane proteins

H. Sahl, J. Bandow, Ute Krämer, 2014, Proceedings of the National Academy of Sciences.

Crystal Structures of the Choline/Acetylcholine Substrate-binding Protein ChoX from Sinorhizobium meliloti in the Liganded and Unliganded-Closed States*

E. Bremer, S. Smits, L. Schmitt, 2008, Journal of Biological Chemistry.

Structural analysis of the choline-binding protein ChoX in a semi-closed and ligand-free conformation

E. Bremer, S. Smits, L. Schmitt, 2009, Biological chemistry.

Clostridium difficile: A bad bug goes into defensive mode.

E. Bremer, 2017, Environmental microbiology.

The osmoprotectant proline betaine is a major substrate for the binding-protein-dependent transport system ProU of Escherichia coli K-12

E. Bremer, M. Haardt, B. Kempf, 1995, Molecular and General Genetics MGG.

Identification of a segment of the Escherichia coli Tsx protein that functions as a bacteriophage receptor area

E. Bremer, H. Fsihi, H. Schneider, 1993, Journal of bacteriology.

Tinkering with Osmotically Controlled Transcription Allows Enhanced Production and Excretion of Ectoine and Hydroxyectoine from a Microbial Cell Factory

E. Bremer, Nadine Stöveken, Laura Czech, 2017, Applied and Environmental Microbiology.

Single amino acid substitutions affecting the substrate specificity of the Escherichia coli K-12 nucleoside-specific Tsx channel.

E. Bremer, H. Fsihi, B. Kottwitz, 1993, The Journal of biological chemistry.

Transcriptional regulation of ectoine catabolism in response to multiple metabolic and environmental cues

Jeroen S. Dickschat, J. Heider, E. Bremer, 2017, Environmental microbiology.

Systems metabolic engineering of Corynebacterium glutamicum for production of the chemical chaperone ectoine

Christoph Wittmann, Judith Becker, Michael Kohlstedt, 2013, Microbial Cell Factories.

Coping with osmotic challenges : osmoregulation through accumulation and release of compatible solutes in bacteria

E. Bremer, 2000 .

Osmosensing and osmoregulatory compatible solute accumulation by bacteria.

B. Poolman, E. Bremer, J. M. Wood, 2001, Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.

Synthesis and Uptake of the Compatible Solutes Ectoine and 5-Hydroxyectoine by Streptomyces coelicolor A3(2) in Response to Salt and Heat Stresses

E. Bremer, M. Jebbar, A. Pierik, 2008, Applied and Environmental Microbiology.

Synthesis of the Compatible Solute Ectoine in Virgibacillus pantothenticus Is Triggered by High Salinity and Low Growth Temperature

E. Bremer, T. Hoffmann, Anne U. Kuhlmann, 2008, Applied and Environmental Microbiology.

Synthesis, Release, and Recapture of Compatible Solute Proline by Osmotically Stressed Bacillus subtilis Cells

E. Bremer, T. Hoffmann, S. Moses, 2012, Applied and Environmental Microbiology.

The γ-Aminobutyrate Permease GabP Serves as the Third Proline Transporter of Bacillus subtilis

E. Bremer, K. Gunka, F. Commichau, 2013, Journal of bacteriology.

Proline Utilization by Bacillus subtilis: Uptake and Catabolism

A. Sonenshein, B. Belitsky, E. Bremer, 2011, Journal of bacteriology.

Ectoine Synthase: An Iron‐Dependent Member of the Cupin Superfamily

E. Bremer, S. Smits, Laura Czech, 2020, Encyclopedia of Inorganic and Bioinorganic Chemistry.

and Proline Pools Response to Intracellular Glycine Betaine Bacillus subtilis and Its Modulation in Expression in opuA Osmotic Control of

U. Völker, E. Bremer, T. Hoffmann, 2013 .

Structural Basis for the Binding of Compatible Solutes by ProX from the Hyperthermophilic Archaeon Archaeoglobus fulgidus*

K. Diederichs, A. Schiefner, W. Welte, 2004, Journal of Biological Chemistry.

Mutational activation of the RocR activator and of a cryptic rocDEF promoter bypass loss of the initial steps of proline biosynthesis in Bacillus subtilis.

Lope A. Flórez, J. Stülke, E. Bremer, 2014, Environmental microbiology.

Osmotically Controlled Synthesis of the Compatible Solute Proline Is Critical for Cellular Defense of Bacillus subtilis against High Osmolarity

E. Bremer, T. Hoffmann, J. Brill, 2011, Journal of bacteriology.

Management of Osmoprotectant Uptake Hierarchy in Bacillus subtilis via a SigB-Dependent Antisense RNA

U. Völker, E. Hammer, U. Mäder, 2020, Frontiers in Microbiology.

OpuF, a New Bacillus Compatible Solute ABC Transporter with a Substrate-Binding Protein Fused to the Transmembrane Domain

E. Bremer, L. Teichmann, H. Kümmel, 2018, Applied and Environmental Microbiology.

Guardians in a stressful world: the Opu family of compatible solute transporters from Bacillus subtilis

E. Bremer, T. Hoffmann, 2017, Biological chemistry.

Plant-derived compatible solutes proline betaine and betonicine confer enhanced osmotic and temperature stress tolerance to Bacillus subtilis.

E. Bremer, S. Smits, T. Hoffmann, 2014, Microbiology.

Bacillus subtilis Serves as the Third Proline Transporter of-Aminobutyrate Permease GabP

E. Bremer, K. Gunka, F. Commichau, 2013 .

Osmoprotection of Bacillus subtilis through Import and Proteolysis of Proline-Containing Peptides

E. Bremer, Adrienne Zaprasis, T. Hoffmann, 2012, Applied and Environmental Microbiology.

Proline-Containing Peptides Import and Proteolysis of Osmoprotection of Bacillus subtilis through

E. Bremer, Adrienne Zaprasis, T. Hoffmann, 2012 .

Protection of Bacillus subtilis against Cold Stress via Compatible-Solute Acquisition

E. Bremer, T. Hoffmann, 2011, Journal of bacteriology.

Cellular Adjustments of Bacillus subtilis and Other Bacilli to Fluctuating Salinities

E. Bremer, M. Pittelkow, 2011 .

Stress responses ofBacillus subtilis to high osmolarity environments: Uptake and synthesis of osmoprotectants

E. Bremer, B. Kempf, 1998, Journal of Biosciences.

Osmotically Induced Synthesis of the Compatible Solute Hydroxyectoine Is Mediated by an Evolutionarily Conserved Ectoine Hydroxylase*

E. Bremer, A. Pierik, N. Pica, 2007, Journal of Biological Chemistry.

High-Salinity-Induced Iron Limitation in Bacillus subtilis

U. Völker, E. Bremer, T. Hoffmann, 2002, Journal of bacteriology.

High-Affinity Transport of Choline-O-Sulfate and Its Use as a Compatible Solute inBacillus subtilis

J. Boch, E. Bremer, J. A. Le Good, 1999, Applied and Environmental Microbiology.

Response of Bacillus subtilis to high osmolarity: uptake of carnitine, crotonobetaine and γ-butyrobetaine via the ABC transport system OpuC.

E. Bremer, R. Kappes, 1998, Microbiology.

Ectoine functions as an osmoprotectant in Bacillus subtilis and is accumulated via the ABC-transport system OpuC

E. Bremer, M. Jebbar, Carsten von Blohn, 1997 .

Marine Proteobacteria metabolize glycolate via the β-hydroxyaspartate cycle

R. Amann, B. Fuchs, P. Claus, 2019, Nature.

Genes for the synthesis of the osmoprotectant glycine betaine from choline in the moderately halophilic bacterium Halomonas elongata DSM 3043, USA.

J. J. Nieto, C. Vargas, E. Bremer, 2000, Microbiology.

The Ectoine Hydroxylase: A Nonheme-Containing Iron(II) and 2-Oxoglutarate-Dependent Dioxygenase

E. Bremer, S. Smits, Nils Widderich, 2016 .

A plasmid vector for simultaneous generation of lacZ protein fusions and npt-II operon fusions in vivo

T. Teeri, E. Bremer, E. T. Palva, 1987 .

Genome Sequences of the Biotechnologically Important Bacillus megaterium Strains QM B1551 and DSM319

Dieter Jahn, Mitrick A. Johns, Jacques Ravel, 2011, Journal of bacteriology.

Regulation of envelope protein composition during adaptation to osmotic stress in Escherichia coli

G. May, E. Bremer, M. Villarejo, 1986, Journal of bacteriology.

L-Proline Synthesis Mutants of Bacillus subtilis Overcome Osmotic Sensitivity by Genetically Adapting L-Arginine Metabolism

H. Link, E. Bremer, F. Commichau, 2022, Frontiers in Microbiology.

Coping with osmotic challenges: osmoregulation through accumulation and release of compatible solutes in B. subtilis

E. Bremer, 2000 .

Low-copy-number T7 vectors for selective gene expression and efficient protein overproduction in Escherichia coli.

E. Bremer, H. Fsihi, P. Dersch, 1994, FEMS microbiology letters.

Overproduction, crystallization and X-ray diffraction data analysis of ectoine synthase from the cold-adapted marine bacterium Sphingopyxis alaskensis.

E. Bremer, S. Smits, S. Kobus, 2015, Acta crystallographica. Section F, Structural biology communications.

Overexpression, crystallization and preliminary X-ray crystallographic analysis of the ectoine hydroxylase from Sphingopyxis alaskensis.

E. Bremer, S. Smits, A. Hoeppner, 2014, Acta crystallographica. Section F, Structural biology communications.

Control of potassium homeostasis is an essential function of the second messenger cyclic di-AMP in Bacillus subtilis

D. Hertel, R. Daniel, J. Stülke, 2017, Science Signaling.

Adaptation of Escherichia coli to high osmolarity environments: osmoregulation of the high-affinity glycine betaine transport system proU.

E. Bremer, J. M. Lucht, 1994, FEMS microbiology reviews.

RsbV-Independent Induction of the SigB-Dependent General Stress Regulon of Bacillus subtilis during Growth at High Temperature

U. Völker, E. Bremer, L. Steil, 2004, Journal of bacteriology.

Temperature during Growth at High Bacillus subtilis SigB-Dependent General Stress Regulon of RsbV-Independent Induction of the

U. Völker, E. Bremer, L. Steil, 2004 .

With a pinch of extra salt—Did predatory protists steal genes from their food?

E. Bremer, Laura Czech, 2018, PLoS biology.

Functional overexpression and in vitro re‐association of OpuA, an osmotically regulated ABC‐transport complex from Bacillus subtilis

E. Bremer, L. Schmitt, Carsten Horn, 2005, FEBS letters.

Characterisation of the promoters for the ompA gene which encodes a major outer membrane protein of Escherichia coli

S. Cole, E. Bremer, U. Henning, 2004, Molecular and General Genetics MGG.

Bacillus subtilis : characterization of OpuD . osmoprotectant glycine betaine operate in Three transport systems for the

E. Bremer, B. Kempf, R. Kappes, 1996 .

Ectoine and Hydroxyectoine as Protectants against Osmotic and Cold Stress: Uptake through the SigB-Controlled Betaine-Choline- Carnitine Transporter-Type Carrier EctT from Virgibacillus pantothenticus

E. Bremer, M. Jebbar, T. Hoffmann, 2011, Journal of bacteriology.

Identification ofaSegment oftheEscherichia coli TsxProtein ThatFunctions asaBacteriophage Receptor Area

E. Bremer, H. Schneider, B. Mygind, 1993 .

Stress‐induced activation of the proline biosynthetic pathway in Bacillus subtilis: a population‐wide and single‐cell study of the osmotically controlled proHJ promoter

O. Kuipers, E. Bremer, T. Hoffmann, 2022, Microbial biotechnology.

Degradation of the microbial stress protectants and chemical chaperones ectoine and hydroxyectoine by a bacterial hydrolase–deacetylase complex

E. Bremer, A. Seubert, F. Altegoer, 2020, The Journal of Biological Chemistry.

Arsenobetaine: an ecophysiologically important organoarsenical confers cytoprotection against osmotic stress and growth temperature extremes

E. Bremer, S. Smits, L. Schmitt, 2018, Environmental microbiology.

Compatible Solute Synthesis and Import by the Moderate Halophile Spiribacter salinus: Physiology and Genomics

J. Heider, E. Bremer, A. Ventosa, 2018, Front. Microbiol..

Two MarR-Type Repressors Balance Precursor Uptake and Glycine Betaine Synthesis in Bacillus subtilis to Provide Cytoprotection Against Sustained Osmotic Stress

E. Bremer, A. Seubert, S. Freibert, 2020, Frontiers in Microbiology.

The GbsR Family of Transcriptional Regulators: Functional Characterization of the OpuAR Repressor

E. Bremer, Bianca Warmbold, Stefanie Ronzheimer, 2018, Front. Microbiol..

Osmoregulation in Bacillus subtilis: synthesis of the osmoprotectant glycine betaine from exogenously provided choline

J. Boch, E. Bremer, B. Kempf, 1994, Journal of bacteriology.

Cloned structural genes for the osmotically regulated binding‐protein‐dependent glycine betaine transport system (ProU) of Escherichia coli K‐12

A. Middendorf, E. Bremer, E. Faatz, 1988, Molecular microbiology.

A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli

Ian R. Booth, Charles J. Dorman, Erhard Bremer, 1988, Cell.

OpuA, an Osmotically Regulated Binding Protein-dependent Transport System for the Osmoprotectant Glycine Betaine in Bacillus subtilis(*)

E. Bremer, B. Kempf, 1995, The Journal of Biological Chemistry.

Osmoregulation of the opuE proline transport gene from Bacillus subtilis: contributions of the sigma A‐ and sigma B‐dependent stress‐responsive promoters

E. Bremer, F. Spiegelhalter, 1998, Molecular microbiology.

Characterization of mutations affecting the osmoregulated proU promoter of Escherichia coli and identification of 5' sequences required for high-level expression

E. Bremer, J. M. Lucht, 1991, Journal of bacteriology.

Characterization ofMutations Affecting theOsmoregulated proU Promoter ofEscherichia coli andIdentification of5'Sequences Required forHigh-Level Expression

Erhard Bremer, E. Bremer, 1991 .

Characterization of the osmoregulated Escherichia coli proU promoter and identification of ProV as a membrane‐associated protein

G. May, E. Bremer, M. Haardt, 1989, Molecular microbiology.

Analysis and DNA sequence of the osmoregulatedtreA gene encoding the periplasmic trehalase ofEscherichia coli K12

W. Boos, A. Middendorf, E. Bremer, 1989, Molecular and General Genetics MGG.

Identification of Differentially Expressed Genes during Bacillus subtilis Spore Outgrowth in High-Salinity Environments Using RNA Sequencing

O. Kuipers, E. Bremer, K. Madela, 2016, Front. Microbiol..

Uptake and synthesis of compatible solutes as microbial stress responses to high-osmolality environments

E. Bremer, E. Bremer, B. Kempf, 1998, Archives of Microbiology.

Responses of Microorganisms to Osmotic Stress.

E. Bremer, R. Krämer, 2019, Annual review of microbiology.

Alignment of genes from the 9-minute region (araJ to tsx) of the Escherichia coli K-12 linkage map to the physical map

W. Boos, E. Bremer, J. M. Lucht, 1992, Journal of bacteriology.

Double negative and positive control of tsx expression in Escherichia coli

A. Middendorf, E. Bremer, P. Gerlach, 1988, Journal of bacteriology.

The architecture of the diaminobutyrate acetyltransferase active site provides mechanistic insight into the biosynthesis of the chemical chaperone ectoine

Jeroen S. Dickschat, E. Bremer, S. Smits, 2020, Journal of Biological Chemistry.

Molecular dynamics simulations and structure-guided mutagenesis provide insight into the architecture of the catalytic core of the ectoine hydroxylase.

Holger Gohlke, Daniel Mulnaes, Erhard Bremer, 2014, Journal of molecular biology.

Impact of high salinity and the compatible solute glycine betaine on gene expression of Bacillus subtilis.

M. Hecker, U. Völker, U. Mäder, 2020, Environmental microbiology.

Role of the Extremolytes Ectoine and Hydroxyectoine as Stress Protectants and Nutrients: Genetics, Phylogenomics, Biochemistry, and Structural Analysis

J. Heider, E. Bremer, S. Smits, 2018, Genes.

Two evolutionarily closely related ABC transporters mediate the uptake of choline for synthesis of the osmoprotectant glycine betaine in Bacillus subtilis

J. Boch, E. Bremer, S. Kneip, 1999, Molecular microbiology.

Lipoprotein from the osmoregulated ABC transport system OpuA of Bacillus subtilis: purification of the glycine betaine binding protein and characterization of a functional lipidless mutant

E. Bremer, B. Kempf, J. Gade, 1997, Journal of bacteriology.

Mechanisms of Cellular Protein Localization

E. Sodergren, S. Garrett, T. Silhavy, 1984 .

Biochemical Properties of Ectoine Hydroxylases from Extremophiles and Their Wider Taxonomic Distribution among Microorganisms

J. Heider, E. Bremer, S. Smits, 2014, PloS one.

Transcriptional regulation of the cytR repressor gene of Escherichia coli: autoregulation and positive control by the cAMP/CAP complex

P. Valentin‐Hansen, E. Bremer, P. Gerlach, 1990, Molecular Microbiology.

Regulation of the Escherichia coli water channel gene aqpZ.

W. Bishai, G. Calamita, P. Agre, 1998, Proceedings of the National Academy of Sciences of the United States of America.

A novel amidohydrolase gene from Bacillus subtilis cloning: DNA-sequence analysis and map position of amhX.

E. Bremer, B. Kempf, Erhard Bremer, 1996, FEMS microbiology letters.

In vitro reconstitution of osmoregulated expression of proU of Escherichia coli.

E. Bremer, W. Prince, M. Villarejo, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Stress Responses of the Industrial Workhorse Bacillus licheniformis to Osmotic Challenges

M. Hecker, M. Lalk, B. Jürgen, 2013, PloS one.

Monitoring conformational changes during the catalytic cycle of OpuAA, the ATPase subunit of the ABC transporter OpuA from Bacillus subtilis.

E. Bremer, L. Schmitt, Carsten Horn, 2008, The Biochemical journal.

T-box-mediated control of the anabolic proline biosynthetic genes of Bacillus subtilis.

E. Bremer, H. Putzer, T. Hoffmann, 2011, Microbiology.

Biosynthesis of the Stress-Protectant and Chemical Chaperon Ectoine: Biochemistry of the Transaminase EctB

E. Bremer, S. Smits, T. Erb, 2019, Front. Microbiol..

EctD-mediated biotransformation of the chemical chaperone ectoine into hydroxyectoine and its mechanosensitive channel-independent excretion

E. Bremer, Nadine Stöveken, Laura Czech, 2016, Microbial Cell Factories.

The BCCT family of carriers: from physiology to crystal structure

E. Bremer, C. Ziegler, R. Krämer, 2010, Molecular microbiology.

Osmotically Regulated Synthesis of the Compatible Solute Ectoine in Bacillus pasteurii and Related Bacillus spp

Erhard Bremer, E. Bremer, Anne U. Kuhlmann, 2002, Applied and Environmental Microbiology.

Synthesis of 5-Hydroxyectoine from Ectoine: Crystal Structure of the Non-Heme Iron(II) and 2-Oxoglutarate-Dependent Dioxygenase EctD

A. Heine, K. Reuter, E. Bremer, 2010, PloS one.

cAMP-CRP activator complex and the CytR repressor protein bind co-operatively to the cytRP promoter in Escherichia coli and CytR antagonizes the cAMP-CRP-induced DNA bend.

P. Valentin-Hansen, H. Pedersen, E. Bremer, 1992, Journal of molecular biology.

Synthesis of the Escherichia coli K‐12 nucleoid‐associated DNA‐binding protein H‐NS is subjected to growth‐phase control and autoregulation

E. Bremer, P. Dersch, Keratin Schmidt, 1993, Molecular microbiology.

Cation-π Interactions as Determinants for Binding of the Compatible Solutes Glycine Betaine and Proline Betaine by the Periplasmic Ligand-binding Protein ProX from Escherichia coli*

Kay Diederichs, Erhard Bremer, K. Diederichs, 2004, Journal of Biological Chemistry.

Physiological and Molecular Responses of Bacillus subtilis to Hypertonicity: Utilization of Evolutionarily Conserved Adaptation Strategies

E. Bremer, T. Hoffmann, Gabriele Nau-Wagner, 2004 .

Analysis of the tsx gene, which encodes a nucleoside-specific channel-forming protein (Tsx) in the outer membrane of Escherichia coli.

P. Valentin‐Hansen, J. Martinussen, A. Middendorf, 1990, Gene.

A Comprehensive Proteomics and Transcriptomics Analysis of Bacillus subtilis Salt Stress Adaptation

Michael Hecker, Erhard Bremer, Hannes Hahne, 2009, Journal of bacteriology.

Genome-Wide Transcriptional Profiling Analysis of Adaptation of Bacillus subtilis to High Salinity

U. Völker, E. Bremer, L. Steil, 2003, Journal of bacteriology.

The crystal structure of UehA in complex with ectoine-A comparison with other TRAP-T binding proteins.

E. Bremer, S. Smits, L. Schmitt, 2009, Journal of molecular biology.

University of Groningen Identification of Differentially Expressed Genes during Bacillus subtilis Spore Outgrowth in High-Salinity Environments Using RNA Sequencing

O. Kuipers, E. Bremer, K. Madela, 2019 .

Management of Osmotic Stress by Bacillus Subtilis: Genetics and Physiology

E. Bremer, T. Hoffmann, 2016 .

Salt‐sensitivity of σH and Spo0A prevents sporulation of Bacillus subtilis at high osmolarity avoiding death during cellular differentiation

Fernando H. Ramírez-Guadiana, D. Rudner, E. Bremer, 2016, Molecular Microbiology.

Uptake of Amino Acids and Their Metabolic Conversion into the Compatible Solute Proline Confers Osmoprotection to Bacillus subtilis

E. Bremer, Anne Kerres, Adrienne Zaprasis, 2014, Applied and Environmental Microbiology.

Chill Induction of the SigB-Dependent General Stress Response in Bacillus subtilis and Its Contribution to Low-Temperature Adaptation

U. Völker, E. Bremer, T. Hoffmann, 2003, Journal of bacteriology.

Transposition of λplacMu is mediated by the A protein altered at its carboxy-terminal end

G. Weinstock, T. Silhavy, E. Bremer, 1988 .

Adaptation of Bacillus subtilis to growth at low temperature: a combined transcriptomic and proteomic appraisal.

C. Scharf, U. Völker, E. Bremer, 2006, Microbiology.

A Specialized Aspartokinase Enhances the Biosynthesis of the

J. Heider, R. Jensen, E. Bremer, 2011 .

Osmostress response in Bacillus subtilis: characterization of a proline uptake system (OpuE) regulated by high osmolarity and the alternative transcription factor sigma B

E. Bremer, B. Kempf, R. Kappes, 1997, Molecular microbiology.

Illuminating the catalytic core of ectoine synthase through structural and biochemical analysis

Jeroen S. Dickschat, J. Heider, E. Bremer, 2019, Scientific Reports.

Enhanced Glutamate Synthesis and Export by the Thermotolerant Emerging Industrial Workhorse Bacillus methanolicus in Response to High Osmolarity

E. Bremer, O. Zelder, T. Hoffmann, 2021, Frontiers in Microbiology.

Genetic Control of Osmoadaptive Glycine Betaine Synthesis in Bacillus subtilis through the Choline-Sensing and Glycine Betaine-Responsive GbsR Repressor

J. Boch, E. Bremer, T. Hoffmann, 2012, Journal of bacteriology.

KtrAB and KtrCD: Two K+ Uptake Systems in Bacillus subtilis and Their Role in Adaptation to Hypertonicity

E. Bremer, N. Uozumi, E. Bakker, 2003, Journal of bacteriology.

Synthesis of the osmoprotectant glycine betaine in Bacillus subtilis: characterization of the gbsAB genes

J. Boch, E. Bremer, R. Schmid, 1996, Journal of bacteriology.

Isolation and characterization of mutants deleted for the sulA-ompA region of the Escherichia coli K-12 chromosome

S. Cole, T. Silhavy, E. Bremer, 1986 .

Purification, crystallization and preliminary crystallographic analysis of the periplasmic binding protein ProX from Escherichia coli.

J. Breed, W. Welte, E. Bremer, 2001 .

The nucleoid-associated DNA-binding protein H-NS is required for the efficient adaptation of Escherichia coli K-12 to a cold environment

E. Bremer, S. Kneip, P. Dersch, 1994, Molecular and General Genetics MGG.

The osmZ (bglY) gene encodes the DNA-binding protein H-NS (H1a), a component of the Escherichia coli K12 nucleoid

G. May, A. Middendorf, E. Bremer, 1990, Molecular and General Genetics MGG.

Analysis of a mutated phage T6 receptor protein of Escherichia coli K12

A. Middendorf, E. Bremer, C. Maier, 1990, Molecular and General Genetics MGG.

Binding protein dependent transport of glycine betaine and its osmotic regulation in Escherichia coli K12

G. May, E. Bremer, E. Faatz, 1986, Molecular and General Genetics MGG.

The aquaporin‐Z water channel gene of Escherichia coli: Structure, organization and phylogeny

K. Rudd, G. Calamita, P. Agre, 1997 .

The aquaporin-Z water channel gene of Escherichia coli: structure, organization and phylogeny.

K. Rudd, W. Bishai, G. Calamita, 1997, Biology of the cell.

pOSEX: vectors for osmotically controlled and finely tuned gene expression in Escherichia coli.

E. Bremer, S. Kneip, B. Herbst, 1994, Gene.

The cyclic AMP (cAMP)-cAMP receptor protein complex functions both as an activator and as a corepressor at the tsx-p2 promoter of Escherichia coli K-12

P. Valentin-Hansen, H. Pedersen, J. Martinussen, 1991, Journal of bacteriology.

Structural and functional characterization of the bacterial biofilm activator RemA

E. Bremer, T. Hoffmann, F. Altegoer, 2021, Nature Communications.

Adaptation to Changing Osmolanty

E. Bremer, 2002 .

The MocR/GabR Ectoine and Hydroxyectoine Catabolism Regulator EnuR: Inducer and DNA Binding

Wieland Steinchen, E. Bremer, S. Smits, 2021, Frontiers in Microbiology.

Thermoprotection of Bacillus subtilis by Exogenously Provided Glycine Betaine and Structurally Related Compatible Solutes: Involvement of Opu Transporters

E. Bremer, G. Holtmann, 2004, Journal of bacteriology.

A model industrial workhorse: Bacillus subtilis strain 168 and its genome after a quarter of a century

A. Danchin, C. Médigue, C. Harwood, 2023, Microbial biotechnology.

Strangers in the archaeal world: osmostress-responsive biosynthesis of ectoine and hydroxyectoine by the marine thaumarchaeon Nitrosopumilus maritimus.

Jeroen S. Dickschat, M. Könneke, J. Heider, 2016, Environmental microbiology.

Abiotic stress protection by ecologically abundant dimethylsulfoniopropionate and its natural and synthetic derivatives: insights from Bacillus subtilis.

Jeroen S. Dickschat, E. Bremer, S. Smits, 2015, Environmental microbiology.

The crystal structure of the substrate-binding protein OpuBC from Bacillus subtilis in complex with choline.

E. Bremer, S. Smits, L. Schmitt, 2011, Journal of molecular biology.

Biochemical and Structural Analysis of the Bacillus subtilis ABC Transporter OpuA and Its Isolated Subunits

E. Bremer, L. Schmitt, Carsten Horn, 2006, Journal of Molecular Microbiology and Biotechnology.

Cellular adaptation of Clostridioides difficile to high salinity encompasses a compatible solute-responsive change in cell morphology.

D. Jahn, M. Rohde, E. Bremer, 2022, Environmental microbiology.

Molecular determinants for substrate specificity of the ligand-binding protein OpuAC from Bacillus subtilis for the compatible solutes glycine betaine and proline betaine.

J. Breed, W. Welte, E. Bremer, 2006, Journal of molecular biology.

Biochemistry and Crystal Structure of Ectoine Synthase: A Metal-Containing Member of the Cupin Superfamily

Jeroen S. Dickschat, J. Heider, E. Bremer, 2016, PloS one.

The ups and downs of ectoine: structural enzymology of a major microbial stress protectant and versatile nutrient

E. Bremer, S. Smits, G. Bange, 2020, Biological chemistry.

Exploiting Substrate Promiscuity of Ectoine Hydroxylase for Regio- and Stereoselective Modification of Homoectoine

U. Linne, E. Bremer, S. Smits, 2019, Front. Microbiol..

The many faces of the unusual biofilm activator RemA

E. Bremer, T. Hoffmann, G. Bange, 2022, BioEssays : news and reviews in molecular, cellular and developmental biology.

Arg149 is involved in switching the low affinity, open state of the binding protein AfProX into its high affinity, closed state.

H. Gohlke, E. Bremer, S. Smits, 2011, Journal of molecular biology.

Dimethylglycine Provides Salt and Temperature Stress Protection to Bacillus subtilis

E. Bremer, S. Smits, T. Hoffmann, 2014, Applied and Environmental Microbiology.

The Compatible-Solute-Binding Protein OpuAC from Bacillus subtilis: Ligand Binding, Site-Directed Mutagenesis, and Crystallographic Studies

E. Bremer, S. Smits, L. Schmitt, 2008, Journal of bacteriology.

Synthesis of the compatible solute proline by Bacillus subtilis: point mutations rendering the osmotically controlled proHJ promoter hyperactive

U. Völker, U. Mäder, E. Bremer, 2017, Environmental microbiology.

Activity of the Osmotically Regulated yqiHIK Promoter from Bacillus subtilis Is Controlled at a Distance

E. Bremer, K. Fischer, 2012, Journal of bacteriology.

Bacterial abl-like genes: production of the archaeal osmolyte $$ {N^{\varepsilon }}{\text{ - acetyl - }}\beta {\text{ - lysine}} $$ by homologous overexpression of the yodP–kamA genes in Bacillus subtilis

H. Santos, V. Müller, E. Bremer, 2011, Applied Microbiology and Biotechnology.

Multiple Genes for the Last Step of Proline Biosynthesis in Bacillus subtilis

A. Sonenshein, B. Belitsky, E. Bremer, 2001, Journal of bacteriology.

From substrate specificity to promiscuity: hybrid ABC transporters for osmoprotectants

E. Bremer, S. Smits, L. Schmitt, 2017, Molecular microbiology.

Crystal Structure of the Ectoine Hydroxylase, a Snapshot of the Active Site*

E. Bremer, S. Smits, Michael H. H. Lenders, 2014, The Journal of Biological Chemistry.

Liberate and Grab It, Ingest and Digest It: the GbdR Regulon of the Pathogen Pseudomonas aeruginosa

E. Bremer, 2013, Journal of bacteriology.

Dimethlyglycine provides salt and temperature stress protection to Bacillus subtilis 3 4

E. Bremer, S. Smits, T. Hoffmann, 2014 .

and subtilis Temperature Stress Protection to Bacillus Dimethylglycine Provides Salt and

E. Bremer, S. Smits, T. Hoffmann, 2014 .

Pseudomonas aeruginosa the GbdR Regulon of the Pathogen Liberate and Grab It, Ingest and Digest It:

E. Bremer, 2014 .

Crystal structure of the ligand-binding protein EhuB from Sinorhizobium meliloti reveals substrate recognition of the compatible solutes ectoine and hydroxyectoine.

E. Bremer, L. Schmitt, M. Jebbar, 2007, Journal of molecular biology.

Nucleotide dependent monomer/dimer equilibrium of OpuAA, the nucleotide-binding protein of the osmotically regulated ABC transporter OpuA from Bacillus subtilis.

E. Bremer, L. Schmitt, Carsten Horn, 2003, Journal of molecular biology.

the gbsAB genes . betaine in Bacillus subtilis : characterization of Synthesis of the osmoprotectant glycine

J. Boch, E. Bremer, R. Schmid, 1996 .

The compatible solute-binding protein OpuAC 2 from Bacillus subtilis : ligand-binding , site 3 directed mutagenesis and crystallographic 4 studies 5 6

E. Bremer, S. Smits, L. Schmitt, 2008 .

Use of phoA and lacZ fusions to study the membrane topology of ProW, a component of the osmoregulated ProU transport system of Escherichia coli

E. Bremer, M. Haardt, E. Bremer, 1996, Journal of bacteriology.

Three transport systems for the osmoprotectant glycine betaine operate in Bacillus subtilis: characterization of OpuD

E. Bremer, B. Kempf, R. Kappes, 1996, Journal of bacteriology.

Cloned structural gene (ompA) for an integral outer membrane protein of Escherichia coli K-12

E. Bremer, U. Henning, E. Beck, 2004, Molecular and General Genetics MGG.