R. Schleif

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An operator at -280 base pairs that is required for repression of araBAD operon promoter: addition of DNA helical turns between the operator and promoter cyclically hinders repression.

T. Dunn, S. Hahn, S. Ogden, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Arabinose C protein: regulation of the arabinose operon in vitro.

J. Greenblatt, R. Schleif, R. Schleif, 1971, Nature: New biology.

Regulation of the L-arabinose operon of Escherichia coli.

R. Schleif, 2000, Trends in genetics : TIG.

Structural basis for ligand-regulated oligomerization of AraC.

C. Wolberger, R. Schleif, S. Soisson, 1997, Science.

The 1.6 A crystal structure of the AraC sugar-binding and dimerization domain complexed with D-fucose.

C. Wolberger, R. Schleif, S. Soisson, 1997, Journal of molecular biology.

Arac/XylS family of transcriptional regulators

A Bairoch, A. Bairoch, J. Ramos, 1997, Microbiology and molecular biology reviews : MMBR.

AraC protein, regulation of the l-arabinose operon in Escherichia coli, and the light switch mechanism of AraC action.

Robert Schleif, R. Schleif, 2010, FEMS microbiology reviews.

In vivo regulation of the Escherichia coli araC promoter

S. Hahn, R. Schleif, 1983, Journal of bacteriology.

A regulatory cascade in the induction of rhaBAD.

R. Schleif, R F Schleif, S M Egan, 1993, Journal of molecular biology.

DNA binding by proteins.

R. Schleif, R Schleif, 1988, Science.

The regulatory region of the L-arabinose operon: a physical, genetic and physiological study.

R. Schleif, J. Lis, R. Schleif, 1975, Journal of molecular biology.

The araC promoter: Transcription, mapping and interaction with the araBAD promoter

J. Hirsh, R. Schleif, 1977, Cell.

Recognition of Overlapping Nucleotides by AraC and the Sigma Subunit of RNA Polymerase

R. Schleif, A. Dhiman, Anjali Dhiman, 2000, Journal of bacteriology.

Induction Kinetics of the l-Arabinose Operon of Escherichia coli

R. Schleif, W. Hess, S. Finkelstein, 1973, Journal of bacteriology.

Control of production of ribosomal protein.

R. Schleif, 1967, Journal of molecular biology.

The salt dependence of the interferon regulatory factor 1 DNA binding domain binding to DNA reveals ions are localized around protein and DNA.

R. Schleif, Victoria V. Hargreaves, 2008, Biochemistry.

Functional domains of the AraC protein.

R. Schleif, S. Bustos, Silvia A. Bustos, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Catabolite Gene Activator Protein Mutations Affecting Activity of the araBAD Promoter

Xin Zhang, R. Schleif, 1998, Journal of bacteriology.

Cooperative Action of the Catabolite Activator Protein and AraC In Vitro at the araFGH Promoter

R. Schleif, Casonya M Johnson, 2000, Journal of bacteriology.

Computational and experimental investigation of constitutive behavior in AraC

A. Damjanovic, R. Schleif, David M. Gullotti, 2014, Proteins.

Structure and properties of a truely apo form of AraC dimerization domain

C. Larkin, R. Schleif, J. Weldon, 2006, Proteins.

The role of rigidity in DNA looping-unlooping by AraC.

M. Wu, R. Schleif, T. Harmer, 2001, Proceedings of the National Academy of Sciences of the United States of America.

High resolution electron microscopic studies of genetic regulation.

J. Hirsh, R. Schleif, 1976, Journal of molecular biology.

DNA looping.

R. Schleif, 1992, Annual review of biochemistry.

Why should DNA loop?

R. Schleif, 1987, Nature.

A dimer of AraC protein contacts three adjacent major groove regions of the araI DNA site.

R. Schleif, W. Hendrickson, R. Schleif, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Variation of half‐site organization and DNA looping by AraC protein.

R. Schleif, J. Carra, J.H. Carra, 1993, The EMBO journal.

L-arabinose transport systems in Escherichia coli K-12

R. Schleif, D. Kolodrubetz, R. Schleif, 1981, Journal of bacteriology.

Repression of the araBAD promoter from araO1.

R. Schleif, D. Lee, L. Huo, 1992, Journal of molecular biology.

AraC protein can activate transcription from only one position and when pointed in only one direction.

R. Schleif, T. Reeder, 1993, Journal of molecular biology.

Solution structure of the DNA binding domain of AraC protein

R. Schleif, M. Rodgers, 2009, Proteins.

Promoter araBAD Affecting Activity of the Catabolite Gene Activator Protein Mutations

Xin Zhang, R. Schleif, 1998 .

Factor Necessary for Ribosomal RNA Synthesis

A. Travers, R. Kamen, R. Schleif, 1970, Nature.

DNA-dependent renaturation of an insoluble DNA binding protein. Identification of the RhaS binding site at rhaBAD.

R. Schleif, S. Egan, 1994, Journal of molecular biology.

Transcription start site and induction kinetics of the araC regulatory gene in Escherichia coli K-12.

R. Schleif, C. Stoner, R. Schleif, 1983, Journal of molecular biology.

Is the amino acid but not the nucleotide sequence of the Escherichia coli araC gene conserved?

R. Schleif, C. Stoner, 1982, Journal of molecular biology.

Missing contact probing of DNA-protein interactions.

R. Schleif, A. Brunelle, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Active Role of the Interdomain Linker of AraC

R. Schleif, Jennifer E. Seedorff, 2011, Journal of bacteriology.

In vivo titration of araC protein

R. Schleif, M. Oeschger, D. Haggerty, 1978, Journal of bacteriology.

Cross-induction of the L-fucose system by L-rhamnose in Escherichia coli

E. Lin, R. Schleif, Y. Zhu, 1987, Journal of bacteriology.

DNA Bending by AraC: a Negative Mutant

R. Schleif, B. Saviola, Robert R. Seabold, 1998, Journal of bacteriology.

Identification of araC protein and two-dimensional gels, its in vivo instability and normal level.

R. Schleif, D. Kolodrubetz, 1981, Journal of molecular biology.

Stabilizing C‐terminal tails on AraC

R. Schleif, Madhushree Ghosh, 2001, Proteins.

Practical Methods in Molecular Biology

R. Schleif, P. C. Wensink, 1981, Springer New York.

Mutations in LOXHD1, a recessive-deafness locus, cause dominant late-onset Fuchs corneal dystrophy.

David S. Parker, N. Katsanis, S. Riazuddin, 2012, American journal of human genetics.

Dual control of arabinose genes on transducing phage λdara

Ronald W. Davis, J. Greenblatt, R. Schleif, 1971 .

Induction of the L-arabinose operon.

R. Schleif, 1969, Journal of molecular biology.

An L-arabinose binding protein and arabinose permeation in Escherichia coli.

R. Schleif, R Schleif, 1969, Journal of molecular biology.

A Career's Work, the l-Arabinose Operon: How It Functions and How We Learned It

R. Schleif, 2021, EcoSal Plus.

Novel Mutation to Dominant Fucose Resistance in the l-Arabinose Operon of Escherichia coli

R. Schleif, N. Nathanson, 1973, Journal of bacteriology.

NovelMutation toDominantFucose Resistance intheL-Arabinose OperonofEscherichia coli'

R. Schleif, N. Nathanson, 1973 .

The isolation and characterization of plaque-forming arabinose transducing bacteriophage λ

J. Lis, R. Schleif, 1975 .

Different cyclic AMP requirements for induction of the arabinose and lactose operons of Escherichia coli.

R. Schleif, J. Lis, R. Schleif, 1973, Journal of molecular biology.

The specificity of lamboid phage late gene induction (lamboid phage late gene specificity).

R. Schleif, 1972, Virology.

L-arabinose operon messenger of Escherichia coli. Its inducibility and translation efficiency relative to lactose operon messenger.

R. Schleif, 1971, Journal of Molecular Biology.

A DNA-assisted binding assay for weak protein-protein interactions.

R. Schleif, Katherine E Frato, 2009, Journal of molecular biology.

Mapping arm-DNA-binding domain interactions in AraC.

M. Wu, R. Schleif, Martin Wu, 2001, Journal of molecular biology.

Fine-structure deletion map of the Escherichia coli L-arabinose operon.

R. Schleif, 1972, Proceedings of the National Academy of Sciences of the United States of America.

Arabinose Alters Both Local and Distal H-D Exchange Rates in the Escherichia coli AraC Transcriptional Regulator.

R. Schleif, Alexander Tischer, M. Auton, 2019, Biochemistry.

Helical Behavior of the Interdomain Linker of the Escherichia coli AraC Protein.

R. Schleif, Matthew Brown, 2019, Biochemistry.

A genetic and physical study of the interdomain linker of E. Coli AraC protein‐a trans‐subunit communication pathway

R. Schleif, D. Toptygin, M. Rodgers, 2016, Proteins.

Understanding the basis of a class of paradoxical mutations in AraC through simulations

Benjamin T. Miller, A. Damjanovic, R. Schleif, 2013, Proteins.

Heterodimers reveal that two arabinose molecules are required for the normal arabinose response of AraC.

R. Schleif, M. Rodgers, 2012, Biochemistry.

A new and unexpected domain–domain interaction in the AraC protein

R. Schleif, S. Cole, 2012, Proteins.

Computational predictions of the mutant behavior of AraC.

Jeffrey J Gray, Robert Schleif, J. J. Gray, 2010, Journal of molecular biology.

Constitutive Mutations in the Escherichia coli AraC Protein

Robert Schleif, R. Schleif, Stephanie Dirla, 2009, Journal of bacteriology.

Specific interactions by the N‐terminal arm inhibit self‐association of the AraC dimerization domain

R. Schleif, J. Weldon, 2006, Protein science : a publication of the Protein Society.

Biochemical and physiological properties of the DNA binding domain of AraC protein.

Robert Schleif, Andrew Timmes, R. Schleif, 2004, Journal of molecular biology.

Overproducing araC protein with lambda-arabinose transducing phage

R. Schleif, David Steffen, 1977, Molecular and General Genetics MGG.

Mutational analysis of residue roles in AraC function.

R. Schleif, Jennifer J Ross, Urszula Gryczynski, 2003, Journal of molecular biology.

Biophysical evidence of arm-domain interactions in AraC.

R. Schleif, R F Schleif, M Ghosh, 2001, Analytical biochemistry.

Apo-AraC actively seeks to loop.

R. Schleif, R F Schleif, R R Seabold, 1998, Journal of molecular biology.

Arm-domain interactions in AraC.

R. Schleif, B. Saviola, R. Seabold, 1998, Journal of molecular biology.

Transcription activation parameters at ara pBAD.

X Zhang, R. Schleif, R Schleif, 1996, Journal of molecular biology.

Reaching out. Locating and lengthening the interdomain linker in AraC protein.

R. Schleif, S. Bustos, R. J. Eustance, 1994, Journal of molecular biology.

Mapping, sequence, and apparent lack of function of araJ, a gene of the Escherichia coli arabinose regulon

R. Schleif, T. Reeder, 1991, Journal of bacteriology.

AraC-DNA looping: orientation and distance-dependent loop breaking by the cyclic AMP receptor protein.

R. Lobell, R. Schleif, 1991, Journal of molecular biology.

Characterization of the Escherichia coli araFGH and araJ promoters.

R. Schleif, W. Hendrickson, C. Stoner, 1990, Journal of molecular biology.

Determining residue-base interactions between AraC protein and araI DNA.

R. Schleif, A. Brunelle, R. Schleif, 1989, Journal of molecular biology.

Positive regulation of the Escherichia coli L-rhamnose operon is mediated by the products of tandemly repeated regulatory genes.

R. Schleif, J. Tobin, R F Schleif, 1987, Journal of molecular biology.

Equilibrium DNA-binding of AraC protein. Compensation for displaced ions.

K. Martin, R. Schleif, R F Schleif, 1987, Journal of molecular biology.

The DNA loop model for ara repression: AraC protein occupies the proposed loop sites in vivo and repression-negative mutations lie in these same sites.

K. Martin, R. Schleif, L. Huo, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Transcription of Escherichia coli ara in vitro. The cyclic AMP receptor protein requirement for PBAD induction that depends on the presence and orientation of the araO2 site.

S. Hahn, R. Schleif, W. Hendrickson, 1986, Journal of molecular biology.

Upstream repression and CRP stimulation of the Escherichia coli L-arabinose operon.

T. Dunn, S. Hahn, R. Schleif, 1984, Journal of molecular biology.

Regulation of the Escherichia coli L-arabinose operon studied by gel electrophoresis DNA binding assay.

W Hendrickson, R. Schleif, W. Hendrickson, 1984, Journal of molecular biology.

The araE low affinity L-arabinose transport promoter. Cloning, sequence, transcription start site and DNA binding sites of regulatory proteins.

R. Schleif, C. Stoner, R. Schleif, 1983, Journal of molecular biology.

Arabinose-inducible promoter from Escherichia coli. Its cloning from chromosomal DNA, identification as the araFG promoter and sequence.

R. Schleif, B. E. Kosiba, 1982, Journal of molecular biology.

Hyperproduction of araC protein from Escherichia coli.

R. Schleif, M. Favreau, 1982, Biochemistry.

Regulation of the L-arabinose transport operons in Escherichia coli.

R. Schleif, D. Kolodrubetz, R. Schleif, 1981, Journal of molecular biology.

The Escherichia coli L-arabinose operon: binding sites of the regulatory proteins and a mechanism of positive and negative regulation.

S. Ogden, R. Schleif, D. Kolodrubetz, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Nucleotide sequence of the L-arabinose regulatory region of Escherichia coli K12.

R. Schleif, B. R. Smith, 1978, The Journal of biological chemistry.

The regulatory region of the L-arabinose operon: its isolation on a 1000 base-pair fragment from DNA heteroduplexes.

R. Schleif, J. Lis, R. Schleif, 1975, Journal of molecular biology.

Size fractionation of double-stranded DNA by precipitation with polyethylene glycol.

R. Schleif, J. Lis, 1975, Nucleic acids research.

In vivo experiments on the mechanism of action of L-arabinose C gene activator and lactose repressor.

J. Hirsh, R. Schleif, 1973, Journal of molecular biology.

Dual control of arabinose genes on transducing phage lambda-dara.

R. W. Davis, J. Greenblatt, R. Schleif, 1971, Journal of molecular biology.

AraC protein: a love-hate relationship.

Robert Schleif, R. Schleif, 2003, BioEssays : news and reviews in molecular, cellular and developmental biology.

Assaying of organisms for the presence of restriction endonucleases.

R. Schleif, 1980, Methods in enzymology.

L-arabinoseoperon inEscherichia coli , and the light switchmechanismofAraCaction

R. Schleif, R. Schleif, 2010 .

Building family traditions

R. Schleif, 2004, Molecular microbiology.

Hemiplegic mutations in AraC protein.

R. Schleif, W. Reed, Wendy L. Reed, 1999, Journal of molecular biology.

The linker region of AraC protein

R. Schleif, R. J. Eustance, 1996, Journal of bacteriology.

In vivo induction kinetics of the arabinose promoters in Escherichia coli

C. M. Johnson, R. Schleif, Casonya M Johnson, 1995, Journal of bacteriology.

Modulation of DNA binding by gene-specific transcription factors.

R. Schleif, 2013, Biochemistry.

In vivo DNA loops in araCBAD: size limits and helical repeat.

R. Schleif, R F Schleif, D H Lee, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Origin of chloramphenicol particle protein.

R. Schleif, 1968, Journal of molecular biology.

Kinetics of the onset of catabolite repression in Escherichia coli as determined by lac messenger ribonucleic acid initiations and intracellular cyclic adenosine 3',5'-monophosphate levels

R. Schleif, D. Haggerty, 1975, Journal of bacteriology.

DNA looping.

R. Schleif, R Schleif, 1988, Science.

Alternative DNA loops regulate the arabinose operon in Escherichia coli.

K. Martin, R. Schleif, L. Huo, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Deletion analysis of the Escherichia coli ara PC and PBAD promoters.

T. Dunn, R. Schleif, R. Schleif, 1984, Journal of molecular biology.

Isolation and Characterization of a Streptolydigin Resistant RNA Polymerase

R. Schleif, 1969, Nature.

DNA tape measurements of AraC

R. Schleif, M. Rodgers, 2007, Nucleic acids research.

Purification and properties of RhaR, the positive regulator of the L-rhamnose operons of Escherichia coli.

R. Schleif, J. Tobin, R. Schleif, 1990, Journal of molecular biology.

Promoter araFGH Activator Protein and AraC In Vitro at the Cooperative Action of the Catabolite

R. Schleif, Casonya M Johnson, 2000 .

Transcription from the rha operon psr promoter.

R. Schleif, J. Tobin, R F Schleif, 1990, Journal of molecular biology.

The C-terminal End of AraC Tightly Binds to the Rest of Its Domain*

R. Schleif, T. Harmer, 2001, The Journal of Biological Chemistry.

Strengthened Arm-Dimerization Domain Interactions in AraC*

Martin Wu, R. Schleif, 2001, The Journal of Biological Chemistry.

Robert Schleif Polymerase AraC and the Sigma Subunit of RNA Recognition of Overlapping Nucleotides

R. Schleif, Anjali Dhiman, 2000 .

Isolation and physical characterization of random insertions in Staphylococcal nuclease.

R. Schleif, D. M. Nguyen, 1998, Journal of molecular biology.

Arm–domain interactions can provide high binding cooperativity

C. Wolberger, R. Schleif, 2004, Protein science : a publication of the Protein Society.

Arm‐domain interactions in proteins: a review

R. Schleif, 1999, Proteins.

Working with Nucleic Acids

R. Schleif, P. C. Wensink, 1981 .

Where to From Here?

R. Schleif, M. Espinosa, 2022, Frontiers in Molecular Biosciences.

Working with Proteins

R. Schleif, P. C. Wensink, 1981 .

Formation of AraC-DNA sandwiches.

R. Schleif, J. Carra, 1993, Nucleic Acids Research.

In vitro construction of plasmids which result in overproduction of the protein product of the araC gene of Escherichia coli

R. Schleif, David Steffen, 1977, Molecular and General Genetics MGG.

Mutations in LOXHD1, a recessive-deafness locus, cause dominant late-onset Fuchs corneal dystrophy.

David S. Parker, N. Katsanis, R. Schleif, 2012, American journal of human genetics.

Functional modes of the regulatory arm of AraC

R. Schleif, N. Holder, M. Rodgers, 2009, Proteins.

Identification of Oligomerizing Peptides*

R. Schleif, M. Rodgers, Anjali Dhiman, 2001, The Journal of Biological Chemistry.

Paucity of sites mutable to constitutivity in the araC activator gene of the L-arabinose operon of Escherichia coli.

R. Schleif, N. Nathanson, 1975, Journal of Molecular Biology.

The arabinose C gene product of Escherichia coli B/r is hyperlabile in a cell free protein synthesis system

R. Schleif, David Steffen, 2004, Molecular and General Genetics MGG.

Transcription in the Lambda-ara Phage

J. Greenblatt, R. Schleif, 1970 .

Altered DNA contacts made by a mutant AraC protein.

R. Schleif, W. Hendrickson, A. Brunelle, 1985, Nucleic acids research.

A portable allosteric mechanism

R. Schleif, Urszula Gryczynski, 2004, Proteins.

The metabolic stability of ribosomal protein

R. Schleif, 2004, Molecular and General Genetics MGG.

Opposite allosteric mechanisms in TetR and CAP

R. Schleif, M. Rodgers, Jennifer E. Seedorff, 2009, Protein science : a publication of the Protein Society.

24 Regulation of the L-Arabinose Catabolic Operon araBAD

R. Schleif, 1992 .