M. Khanfar

发表

Oxadiazol-based mTOR inhibitors with potent antiproliferative activities: synthetic and computational modeling

M. Khanfar, 2022, Molecular Diversity.

Oleuropein potently inhibits mammalian target of rapamycin: possible involvement of tandem anomeric hyperconjugation–Michael reaction

M. Taha, M. Khanfar, 2014, Medicinal Chemistry Research.

Pharmacophore modeling, homology modeling, and in silico screening reveal mammalian target of rapamycin inhibitory activities for sotalol, glyburide, metipranolol, sulfamethizole, glipizide, and pioglitazone.

M. Taha, M. Khanfar, M. AbuKhader, 2013, Journal of molecular graphics & modelling.

Computer-aided discovery of new FGFR-1 inhibitors followed by in vitro validation.

M. Taha, M. Khanfar, Shada J Alabed, 2016, Future medicinal chemistry.

Discovery of novel urokinase plasminogen activator (uPA) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis

M. Taha, Mahmoud A. Al-Sha’er, M. Khanfar, 2014, Journal of Molecular Modeling.

Rational design and semisynthesis of betulinic acid analogues as potent topoisomerase inhibitors.

P. Sylvester, M. Khanfar, F. Badria, 2009, Journal of natural products.

3D-QSAR studies of latrunculin-based actin polymerization inhibitors using CoMFA and CoMSIA approaches.

M. Khanfar, K. E. El Sayed, D. Youssef, 2010, European journal of medicinal chemistry.

Discovery, design, and synthesis of anti-metastatic lead phenylmethylene hydantoins inspired by marine natural products.

M. Khanfar, R. V. van Soest, K. E. El Sayed, 2009, Bioorganic & medicinal chemistry.

New Pim-1 Kinase Inhibitor From the Co-culture of Two Sponge-Associated Actinomycetes

M. Rateb, M. Khanfar, T. Mohammed, 2018, Front. Chem..

Erratum to “Discovery, design, and synthesis of anti-metastatic lead phenylmethylene hydantoins inspired by marine natural products” [Bioorg. Med. Chem. 17 (2009) 1731–1738]

M. Khanfar, R. Soest, G. Shah, 2009 .

A prodrug approach to enhance azelaic acid percutaneous availability

M. Khanfar, E. Khalil, A. Al-Bakri, 2017, Pharmaceutical development and technology.

6-Substituted nicotinic acid analogues, potent inhibitors of CAIII, used as therapeutic candidates in hyperlipidemia and cancer

M. Khanfar, Y. Al-Hiari, Muhammed Alzweiri, 2017, Medicinal Chemistry Research.

Design and pharmacophore modeling of biaryl methyl eugenol analogs as breast cancer invasion inhibitors.

P. Sylvester, M. Khanfar, F. Badria, 2010, Bioorganic & Medicinal Chemistry.

The marine natural-derived inhibitors of glycogen synthase kinase-3beta phenylmethylene hydantoins: In vitro and in vivo activities and pharmacophore modeling.

M. Khanfar, K. E. El Sayed, A. Kaddoumi, 2009, Bioorganic & medicinal chemistry.

Variations in GC–MS Response Between Analytes and Deuterated Analogs

M. Khanfar, Y. Al-Hiari, Muhammed Alzweiri, 2015, Chromatographia.

Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells.

Liwu Fu, S. Ambudkar, Zhe-Sheng Chen, 2010, Biochemical pharmacology.

Protective activity of (1S,2E,4R,6R,7E,11E)-2,7,11-cembratriene-4,6-diol analogues against diisopropylfluorophosphate neurotoxicity: preliminary structure-activity relationship and pharmacophore modeling.

M. Khanfar, K. E. El Sayed, P. Ferchmin, 2013, Bioorganic & medicinal chemistry.

Reversible Small Molecule Inhibitors of MAO A and MAO B with Anilide Motifs

H. Stark, E. Proschak, M. Khanfar, 2020, Drug design, development and therapy.

Phenylmethylene hydantoins as prostate cancer invasion and migration inhibitors. CoMFA approach and QSAR analysis.

M. Khanfar, K. E. El Sayed, Khalid A El Sayed, 2010, European journal of medicinal chemistry.

Discovery of novel GSK-3β inhibitors with potent in vitro and in vivo activities and excellent brain permeability using combined ligand- and structure-based virtual screening.

M. Khanfar, K. E. El Sayed, A. Kaddoumi, 2010, Journal of medicinal chemistry.

DDDT_A_236586 371..393

H. Stark, E. Proschak, M. Khanfar, 2020 .

Design, synthesis, and biological evaluation of novel oxadiazole- and thiazole-based histamine H3R ligands.

H. Stark, M. Khanfar, D. Reiner, 2018, Bioorganic & medicinal chemistry.

Multiple Targeting Approaches on Histamine H3 Receptor Antagonists

H. Stark, K. Nikolić, S. Butini, 2016, Front. Neurosci..

Pachycladins A-E, prostate cancer invasion and migration inhibitory Eunicellin-based diterpenoids from the red sea soft coral Cladiella pachyclados.

M. Khanfar, H. Hassan, K. E. El Sayed, 2010, Journal of natural products.

Structure‐based Pharmacophore Screening Coupled with QSAR Analysis Identified Potent Natural‐product‐derived IRAK‐4 Inhibitors

M. Khanfar, 2021, Molecular informatics.

Sesbania grandiflora L. Poir leaves: A dietary supplement to alleviate type 2 diabetes through metabolic enzymes inhibition

M. Rateb, M. Khanfar, M. Yaseen, 2020 .

Olive Oil‐derived Oleocanthal as Potent Inhibitor of Mammalian Target of Rapamycin: Biological Evaluation and Molecular Modeling Studies

M. Khanfar, M. R. Akl, K. E. El Sayed, 2015, Phytotherapy Research.

Discovery of potent polyphosphate kinase 1 (PPK1) inhibitors using structure‐based exploration of PPK1Pharmacophoric space coupled with docking analyses

M. Khanfar, S. Bardaweel, Rasha M. Bashatwah, 2018, Journal of molecular recognition : JMR.

Identification of a small molecule class to enhance cell-cell adhesion and attenuate prostate tumor growth and metastasis

M. Khanfar, K. E. El Sayed, Mitan R. Gokulgandhi, 2009, Molecular Cancer Therapeutics.

Gas chromatography/trace analysis of derivatized azelaic acid as a stability marker.

M. Khanfar, Muhammed Alzweiri, R. Tarawneh, 2013, Journal of separation science.

Synthesis and characterization of new derivatives of alginic acid and evaluation of their iron(III)-crosslinked beads as potential controlled release matrices

M. Taha, M. Khanfar, R. A. Al Bakain, 2014, Pharmaceutical development and technology.

Semisynthetic Latrunculin Derivatives as Inhibitors of Metastatic Breast Cancer: Biological Evaluations, Preliminary Structure–Activity Relationship and Molecular Modeling Studies

M. Khanfar, D. Youssef, Mohammad A. Khanfar, 2010, ChemMedChem.

Unsupervised pharmacophore modeling combined with QSAR analyses revealed novel low micromolar SIRT2 inhibitors

M. Taha, M. Khanfar, 2017, Journal of molecular recognition : JMR.

Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3Kγ) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis.

M. Taha, Mahmoud A. Al-Sha’er, M. Khanfar, 2014, European journal of medicinal chemistry.

Latrunculin A and its C-17-O-carbamates inhibit prostate tumor cell invasion and HIF-1 activation in breast tumor cells.

M. Khanfar, D. Nagle, D. Youssef, 2008, Journal of natural products.

Methods for evaluation of structural and biological properties of antiinvasive natural products.

M. Khanfar, G. Shah, Mudit Mudit, 2011, Methods in molecular biology.

Discovery of Potent Natural-Product-Derived SIRT2 Inhibitors Using Structure-Based Exploration of SIRT2 Pharmacophoric Space Coupled With QSAR Analyses.

M. Khanfar, Saja AlQtaishat, 2021, Anti-Cancer Agents in Medicinal Chemistry.

Combining docking-based comparative intermolecular contacts analysis and k-nearest neighbor correlation for the discovery of new check point kinase 1 inhibitors

Mutasem O. Taha, Maha Habash, Mohammad A. Khanfar, 2015, Journal of Computer-Aided Molecular Design.

The use of docking-based comparative intermolecular contacts analysis to identify optimal docking conditions within glucokinase and to discover of new GK activators

Mutasem O. Taha, Maha Habash, Mohammad A. Khanfar, 2014, Journal of Computer-Aided Molecular Design.

Elaborate Ligand-Based Modeling Coupled with Multiple Linear Regression and k Nearest Neighbor QSAR Analyses Unveiled New Nanomolar mTOR Inhibitors

Mutasem O. Taha, Mohammad A. Khanfar, M. Taha, 2013, J. Chem. Inf. Model..

Design of semisynthetic analogues and 3D-QSAR study of eunicellin-based diterpenoids as prostate cancer migration and invasion inhibitors.

M. Khanfar, H. Hassan, Asmaa A. Sallam, 2011, European journal of medicinal chemistry.

Discovery of Check Point Kinase 1 (Chk1) Inhibitors as Potential Anticancer Agents Using Ligand-Based Modelling and Virtual Screening

M. Taha, Mahmoud A. Al-Sha’er, M. Khanfar, 2015 .

Development and characterization of 3-(benzylsulfonamido)benzamides as potent and selective SIRT2 inhibitors.

M. Khanfar, A. Kazantsev, R. Silverman, 2014, European journal of medicinal chemistry.

Modified Hummel-Dreyer Method and Molecular Modeling Studies Identified Nicotinic Acid Analogues as Carbonic Anhydrase III Ligands

M. Khanfar, Y. Al-Hiari, Muhammed Alzweiri, 2016 .

Oleuropein potently inhibits mammalian target of rapamycin: possible involvement of tandem anomeric hyperconjugation–Michael reaction

M. Taha, M. Khanfar, 2015, Medicinal Chemistry Research.

Bioactive natural, biocatalytic, and semisynthetic tobacco cembranoids.

M. Khanfar, E. El-Giar, K. E. El Sayed, 2011, Planta medica.

M. Khanfar, K. E. El Sayed, P. Ferchmin, 2013, Bioorganic & Medicinal Chemistry.

Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3Kγ) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis.

M. Taha, Mahmoud A. Al-Sha’er, M. Khanfar, 2014, European journal of medicinal chemistry.

Discovery of natural‐derived Mpro inhibitors as therapeutic candidates for COVID‐19: Structure‐based pharmacophore screening combined with QSAR analysis

M. Khanfar, Nada Salaas, Reem Abumostafa, 2023, Molecular informatics.

Discovery of potent adenosine A2a antagonists as potential anti-Parkinson disease agents. Non-linear QSAR analyses integrated with pharmacophore modeling.

M. Taha, M. Khanfar, Maha Habash, 2016, Chemico-biological interactions.

Discovery, design, and synthesis of anti-metastatic lead phenylmethylene hydantoins inspired by marine natural products.

M. Khanfar, K. E. El Sayed, G. Shah, 2009, Bioorganic & medicinal chemistry.

Latrunculin A and its C-17-O-carbamates inhibit prostate tumor cell invasion and HIF-1 activation in breast tumor cells.

M. Khanfar, D. Nagle, D. Youssef, 2008, Journal of natural products.

Discovery of potent IRAK-4 inhibitors as potential anti-inflammatory and anticancer agents using structure-based exploration of IRAK-4 pharmacophoric space coupled with QSAR analyses

Mohammad A. Khanfar, Saja AlQtaishat, M. Khanfar, 2019, Comput. Biol. Chem..

Development and characterization of 3-(benzylsulfonamido)benzamides as potent and selective SIRT2 inhibitors.

M. Khanfar, A. Kazantsev, R. Silverman, 2014, European journal of medicinal chemistry.

Experimental investigation of concrete breakout strength of anchors in shear within fiber reinforced concrete

M. Khanfar, 2019 .

M. Taha, M. Khanfar, M. AbuKhader, 2013, Journal of molecular graphics & modelling.

Discovery of potent NEK2 inhibitors as potential anticancer agents using structure-based exploration of NEK2 pharmacophoric space coupled with QSAR analyses

M. Khanfar, Saja AlQtaishat, Shada J. Alabed, 2016, Molecular Diversity.