C. Cheng

A. Marshall, C. Cheng, M. Reidenberg, 1993, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Measurement of Urinary Clusterin as an Index of Nephrotoxicity

Philip S Li, M. Goldstein, C. Cheng, 1992, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Rat testicular myotubularin, a protein tyrosine phosphatase expressed by Sertoli and germ cells, is a potential marker for studying cell–cell interactions in the rat testis

B. Silvestrini, E. Samy, C. Cheng, 2000, Journal of cellular physiology.

The inter-Sertoli tight junction permeability barrier is regulated by the interplay of protein phosphatases and kinases: an in vitro study.

C. Cheng, D. Mruk, J. Li, 2001, Journal of andrology.

Sertoli Cell Proteins in Testicular Paracriny

C. Cheng, D. Mruk, C. Cheng, 2000 .

Identification, isolation, and characterization of a 41-kilodalton protein from rat germ cell-conditioned medium exhibiting concentration-dependent dual biological activities.

C. Cheng, W. Lee, G. Aravindan, 1997, Endocrinology.

The immunohistochemical localization of α2-macroglobulin in rat testes is consistent with its role in germ cell movement and spermiation

D. Phillips, C. Cheng, C. Bardin, 1994 .

Sertoli cell synthesizes and secretes a protease inhibitor, alpha 2-macroglobulin.

B. Silvestrini, C. Cheng, A. Guglielmotti, 1990, Biochemistry.

Measurement of a follicle-stimulating hormone-responsive protein of Sertoli cell origin using an enzyme-linked immunoblot assay.

C. Cheng, C. Bardin, W. Lee, 1986, Endocrinology.

Gonadotropins, via cAMP, Negatively Regulate GATA-1 Gene Expression in Testicular Cells.

C. Cheng, D. Mruk, Zhifang Zhang, 2002, Endocrinology.

Tight junctions in the testis: new perspectives

C. Cheng, D. Mruk, C. Cheng, 2010, Philosophical Transactions of the Royal Society B: Biological Sciences.

New frontiers in nonhormonal male contraception.

C. Cheng, D. Mruk, C. Cheng, 2010, Contraception.

The heterogeneity of rat androgen binding protein (rABP) in the vascular compartment differs from that in the testicular tubular lumen. Further evidence for bidirectional secretion of rABP.

C. Cheng, C. Bardin, T. Turner, 1986, Journal of andrology.

The hormonal and cellular control of Sertoli cell secretion.

D. Krieger, C. Cheng, A. Liotta, 1983, Journal of steroid biochemistry.

Demonstration of heavy and light protomers of human testosterone-estradiol-binding globulin.

C. Cheng, C. Bardin, G. Gunsalus, 1983, Journal of steroid biochemistry.

Rat epididymal retinoic acid-binding protein: development of a radioimmunoassay, its tissue distribution, and its changes in selected androgen-dependent organs after orchiectomy.

C. Cheng, J. Grima, I. Zwain, 1992, Endocrinology.

KIF15 supports spermatogenesis via its effects on Sertoli cell microtubule, actin, vimentin and septin cytoskeletons.

C. Cheng, R. Ge, Chris K C Wong, 2021, Endocrinology.

Tumor necrosis factor {alpha} reversibly disrupts the blood-testis barrier and impairs Sertoli-germ cell adhesion in the seminiferous epithelium of adult rat testes.

C. Cheng, W. Xia, D. Mruk, 2006, The Journal of endocrinology.

Actin-binding protein drebrin E is involved in junction dynamics during spermatogenesis

B. Silvestrini, C. Cheng, D. Mruk, 2011, Spermatogenesis.

Functional expression of sperm angiotensin II type I receptor in Xenopus oocyte: modulation of a sperm Ca2+-activated K+ channel.

C. Cheng, P. Leung, H. Chan, 1998, Biochimica et biophysica acta.

Microtubule-associated proteins (MAPs) in microtubule cytoskeletal dynamics and spermatogenesis.

Ming Yan, C. Cheng, R. Ge, 2020, Histology and histopathology.

Clusterin production in the obstructed rabbit kidney: correlations with loss of renal function.

M. Goldstein, O. Jänne, C. Cheng, 1992, Journal of the American Society of Nephrology : JASN.

Cancer/testis (CT) antigens, carcinogenesis and spermatogenesis

C. Cheng, E. W. Wong, Yan-ho Cheng, 2011, Spermatogenesis.

Myosin VIIa Supports Spermatid/Organelle Transport and Cell Adhesion During Spermatogenesis in the Rat Testis

B. Silvestrini, C. Cheng, Chris K C Wong, 2019, Endocrinology.

Roles of Toll-Like Receptors 2 and 4 in Mediating Experimental Autoimmune Orchitis Induction in Mice1

Shutao Zhao, Daishu Han, C. Cheng, 2015, Biology of reproduction.

Regulation of Sertoli cell alpha 2-macroglobulin and clusterin (SGP-2) secretion by peritubular myoid cells.

C. Cheng, L. Saso, C. Bardin, 1993, Biology of reproduction.

Regulation of Clusterin Secretion and mRNA Expression in Astrocytes by Cytokines

C. Cheng, J. Grima, I. Zwain, 1994, Molecular and Cellular Neuroscience.

Diverse secretory patterns of clusterin by epididymis and prostate/seminal vesicles undergoing cell regression after orchiectomy.

C. Cheng, R. Lockshin, C. Bardin, 1990, Endocrinology.

Regulation of Sertoli-germ cell adherens junction dynamics via changes in protein-protein interactions of the N-cadherin-beta-catenin protein complex which are possibly mediated by c-Src and myotubularin-related protein 2: an in vivo study using an androgen suppression model.

C. Cheng, W. Xia, D. Mruk, 2005, Endocrinology.

Regulatory influence of germ cells on sertoli cell function in the pre-pubertal rat after acute irradiation of the testis.

R. Sharpe, N. Guitton, B. Jégou, 2000, International journal of andrology.

CAMSAP2 Is a Microtubule Minus-End Targeting Protein That Regulates BTB Dynamics Through Cytoskeletal Organization.

B. Silvestrini, Q. Lian, C. Cheng, 2019, Endocrinology.

Rescue of perfluorooctanesulfonate (PFOS)-mediated Sertoli cell injury by overexpression of gap junction protein connexin 43

C. Cheng, D. Mruk, Chris K C Wong, 2016, Scientific Reports.

Regulation of blood–testis barrier dynamics by TGF-β3 is a Cdc42-dependent protein trafficking event

C. Cheng, E. W. Wong, D. Mruk, 2010, Proceedings of the National Academy of Sciences.

Sertoli Cell Prostaglandin D2 Synthetase Is a Multifunctional Molecule: Its Expression and Regulation1.

B. Silvestrini, E. Samy, C. Cheng, 2000, Endocrinology.

Sertolin Is a Novel Gene Marker of Cell-Cell Interactions in the Rat Testis*

C. Cheng, D. Mruk, C. Cheng, 1999, The Journal of Biological Chemistry.

Regulation of alpha2-macroglobulin expression in rat Sertoli cells and hepatocytes by germ cells in vitro.

B. Silvestrini, C. Cheng, J. Grima, 1998, Biology of reproduction.

Purification and cellular localization of beta2-microglobulin in the testis.

M. O’Bryan, C. Cheng, C. Cheng, 1997, Life sciences.

Germ cell-conditioned medium contains multiple factors that modulate the secretion of testins, clusterin, and transferrin by Sertoli cells.

C. Pineau, B. Jégou, C. Cheng, 1993, Journal of andrology.

Purification of testosterone-oestradiol-binding globulins from mammalian sera by anion-exchange high performance liquid chromatography.

C. Cheng, C. Bardin, G. Gunsalus, 1985, International journal of andrology.

Tumor necrosis factor α-mediated restructuring of the Sertoli cell barrier in vitro involves matrix metalloprotease 9 (MMP9), membrane-bound intercellular adhesion molecule-1 (ICAM-1) and the actin cytoskeleton

C. Cheng, D. Mruk, B. Bilińska, 2012, Spermatogenesis.

Protein kinases and adherens junction dynamics in the seminiferous epithelium of the rat testis

C. Cheng, Nikki P Y Lee, Nikki P. Y. Lee, 2005, Journal of cellular physiology.

Interleukin‐lo is a regulator of the blood‐testis barrier

C. Cheng, P. Lie, D. Mruk, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

c-Yes regulates cell adhesion at the apical ectoplasmic specialization-blood-testis barrier axis via its effects on protein recruitment and distribution.

C. Cheng, D. Mruk, Xiang Xiao, 2013, American journal of physiology. Endocrinology and metabolism.

Testin and actin are key molecular targets of adjudin, an anti-spermatogenic agent, in the testis

C. Cheng, D. Mruk, C. Cheng, 2011, Spermatogenesis.

Defects of microtubule cytoskeletal organization in NOA human testes

Fei Sun, Mengmeng Sang, C. Cheng, 2022, Reproductive Biology and Endocrinology.

Blood-testis barrier dynamics are regulated by an engagement/disengagement mechanism between tight and adherens junctions via peripheral adaptors.

C. Cheng, Helen H. N. Yan, C. Cheng, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Cell polarity and planar cell polarity (PCP) in spermatogenesis.

C. Cheng, D. Mruk, Chris K C Wong, 2017, Seminars in cell & developmental biology.

Secreted Frizzled‐related protein 1 (sFRP1) regulates spermatid adhesion in the testis via dephosphorylation of focal adhesion kinase and the nectin‐3 adhesion protein complex

C. Cheng, E. W. Wong, Will M. Lee, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Focal adhesion kinase is a blood–testis barrier regulator

C. Cheng, C. Porto, E. W. Wong, 2009, Proceedings of the National Academy of Sciences.

A local regulatory network in the testis mediated by laminin and collagen fragments that supports spermatogenesis

Shiwen Liu, Huitao Li, C. Cheng, 2021, Critical reviews in biochemistry and molecular biology.

Cytokines and junction restructuring events during spermatogenesis in the testis: an emerging concept of regulation.

C. Cheng, D. Mruk, Will M. Lee, 2009, Cytokine & growth factor reviews.

Cytokines and the junction restructuring events during spermatogenesis in the testis: An emerging new concept of regulation

C. Cheng, D. Mruk, Will M. Lee, 2009 .

Regulation of Ectoplasmic Specialization Dynamics in the Seminiferous Epithelium by Focal Adhesion- Associated Proteins in Testosterone-Suppressed Rat Testes

C. Cheng, W. Xia, D. Mruk, 2008 .

Par3/Par6 polarity complex coordinates apical ectoplasmic specialization and blood–testis barrier restructuring during spermatogenesis

C. Cheng, E. W. Wong, D. Mruk, 2008, Proceedings of the National Academy of Sciences.

14-3-3 Protein regulates cell adhesion in the seminiferous epithelium of rat testes.

C. Cheng, E. W. Wong, Shengyi Sun, 2009, Endocrinology.

Planar cell polarity (PCP) proteins support spermatogenesis through cytoskeletal organization in the testis.

B. Silvestrini, C. Cheng, Chris K C Wong, 2021, Seminars in cell & developmental biology.

Purification, cDNA cloning, and developmental changes in the steady-state mRNA level of rat testicular tissue inhibitor of metalloproteases-2 (TIMP-2).

C. Cheng, J. Grima, K. Calcagno, 1996, Journal of andrology.

Is the Cadherin/Catenin Complex a Functional Unit of Cell-Cell Actin-Based Adherens Junctions in the Rat Testis?1

C. Cheng, D. Mruk, Will M. Lee, 2003, Biology of reproduction.

Characterization and Functionality of Proliferative Human Sertoli Cells

G. Rabinovich, C. Cheng, D. Cherbavaz, 2011, Cell transplantation.

A laminin-based local regulatory network in the testis that supports spermatogenesis.

B. Silvestrini, C. Cheng, Chris K C Wong, 2021, Seminars in cell & developmental biology.

Study on the formation of specialized inter‐Sertoli cell junctions in vitro

C. Cheng, Will M. Lee, Sanny S. W. Chung, 1999, Journal of cellular physiology.

An autocrine axis in the testis that coordinates spermiation and blood–testis barrier restructuring during spermatogenesis

C. Cheng, E. W. Wong, D. Mruk, 2008, Proceedings of the National Academy of Sciences.

Sperm Release at Spermiation Is Regulated by Changes in the Organization of Actin- and Microtubule-Based Cytoskeletons at the Apical Ectoplasmic Specialization—A Study Using the Adjudin Model

B. Silvestrini, Q. Lian, C. Cheng, 2017, Endocrinology.

C-type natriuretic peptide regulates blood–testis barrier dynamics in adult rat testes

C. Cheng, W. Xia, D. Mruk, 2007, Proceedings of the National Academy of Sciences.

A modified procedure for replica plating of mammalian cells allowing selection of clones based on gene expression.

C. Cheng, P. Hornsby, Brian Salmons, 1992, BioTechniques.

Mice lacking Axl and Mer tyrosine kinase receptors are susceptible to experimental autoimmune orchitis induction

Yue Zhang, Daishu Han, Peng Liu, 2015, Immunology and cell biology.

Actin‐bundling protein plastin 3 is a regulator of ectoplasmic specialization dynamics during spermatogenesis in the rat testis

Daishu Han, C. Cheng, D. Mruk, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Disruption of the blood-testis barrier integrity by bisphenol A in vitro: is this a suitable model for studying blood-testis barrier dynamics?

C. Cheng, D. Mruk, Will M. Lee, 2009, The international journal of biochemistry & cell biology.

Connexin 43 reboots meiosis and reseals blood‐testis barrier following toxicant‐mediated aspermatogenesis and barrier disruption

B. Silvestrini, Daishu Han, C. Cheng, 2016, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Polymorphisms and intron sequences flanking the alternatively spliced 8-amino-acid exon of gamma2 subunit gene for GABAA receptors.

E. Loh, C. Cheng, A. Cheng, 1997, Biochemical and biophysical research communications.

Planar cell polarity protein Dishevelled 3 (Dvl3) regulates ectoplasmic specialization (ES) dynamics in the testis through changes in cytoskeletal organization

Ming Yan, Q. Lian, C. Cheng, 2019, Cell Death & Disease.

Microtubule cytoskeleton and spermatogenesis - Lesson from studies of toxicant models.

Ming Yan, C. Cheng, R. Ge, 2020, Toxicological sciences : an official journal of the Society of Toxicology.

Development of an enzyme-linked immunosorbent assay, using a monoclonal antibody against α2-macroglobulin, for the diagnosis of systemic lupus erythematosus

B. Silvestrini, C. Cheng, L. Saso, 1999 .

Regulation of blood‐testis barrier assembly in vivo by germ cells

Yi-Xun Liu, Jian Li, C. Cheng, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Spermatogonial stem cells alone are not sufficient to re-initiate spermatogenesis in the rat testis following adjudin-induced infertility.

C. Cheng, Ka-Wai Mok, W. Lee, 2012, International journal of andrology.

Adjudin-mediated Sertoli-germ cell junction disassembly affects Sertoli cell barrier function in vitro and in vivo.

C. Cheng, D. Mruk, Linlin Su, 2010, The international journal of biochemistry & cell biology.

Testis Toxicants: Lesson from Traditional Chinese Medicine (TCM).

Ming Yan, C. Cheng, Lingling Wang, 2021, Advances in experimental medicine and biology.

Palladin is a regulator of actin filament bundles at the ectoplasmic specialization in adult rat testes.

C. Cheng, P. Lie, E. W. Wong, 2013, Endocrinology.

Actin binding proteins and spermiogenesis

C. Cheng, D. Mruk, C. Cheng, 2011, Spermatogenesis.

Modulating the Blood-Testis Barrier Towards Increasing Drug Delivery.

C. Cheng, D. Mruk, Fei Sun, 2020, Trends in pharmacological sciences.

Germ cell control of testin production is inverse to that of other Sertoli cell products.

C. Pineau, B. Jégou, C. Cheng, 1993, Endocrinology.

Identification and partial purification of a germ cell factor that stimulates transferrin secretion by Sertoli cells.

C. Pineau, B. Jégou, C. Cheng, 1993, Recent progress in hormone research.

Testins are localized to the junctional complexes of rat Sertoli and epididymal cells.

D. Phillips, C. Cheng, C. Bardin, 1992, Biology of reproduction.

Testins are structurally related Sertoli cell proteins whose secretion is tightly coupled to the presence of germ cells.

C. Cheng, R. Lockshin, C. Bardin, 1989, The Journal of biological chemistry.

Identification of two testosterone-responsive testicular proteins in Sertoli cell-enriched culture medium whose secretion is suppressed by cells of the intact seminiferous tubule.

C. Cheng, C. Bardin, C. Cheng, 1987, The Journal of biological chemistry.

Abnormal glycosylation of hemopexin in arthritic rats can be blocked by bindarit.

B. Silvestrini, C. Cheng, A. Guglielmotti, 1992, The Journal of rheumatology.

Testicular cell junction: a novel target for male contraception.

C. Cheng, E. W. Wong, D. Mruk, 2009, Current medicinal chemistry.

New insights into FAK function and regulation during spermatogenesis.

C. Celik-Ozenci, C. Cheng, P. Lie, 2014, Histology and histopathology.

Obstruction of the vas deferens alters protein secretion by the rat caput epididymidal epithelium in vivo.

C. Cheng, T. Turner, T. Riley, 1999, Journal of Andrology.

Molecular mechanisms in spermatogenesis

C. Cheng, C. Cheng, C. Y. Cheng, 2008 .

Transcription regulation in spermatogenesis.

C. Cheng, W. Lui, C. Cheng, 2008, Advances in experimental medicine and biology.

Dynamic profiles and transcriptional preferences of histone modifications during spermiogenesis.

Weibing Qin, Yunge Tang, C. Cheng, 2020, Endocrinology.

The identification of gonadotrophin surge inhibiting factor and its role in the regulation of pituitary gonadotrophin secretion.

C. Cheng, D. Danforth, 1993, Human reproduction.

Role of laminin and collagen chains in human spermatogenesis - Insights from studies in rodents and scRNA-Seq transcriptome profiling.

C. Cheng, Xiaolong Wu, Fei Sun, 2021, Seminars in cell & developmental biology.

Human Spermatogenesis and Its Regulation

C. Cheng, D. Mruk, Haiqi Chen, 2017 .

Regulation of spermatogenesis in the microenvironment of the seminiferous epithelium: New insights and advances

C. Cheng, E. W. Wong, D. Mruk, 2010, Molecular and Cellular Endocrinology.

Cadmium-induced testicular injury.

C. Cheng, C. Porto, D. Mruk, 2009, Toxicology and applied pharmacology.

Junction restructuring and spermatogenesis: the biology, regulation, and implication in male contraceptive development.

C. Cheng, D. Mruk, Helen H. N. Yan, 2008, Current topics in developmental biology.

Signaling Proteins That Regulate Spermatogenesis Are the Emerging Target of Toxicant-Induced Male Reproductive Dysfunction

B. Silvestrini, C. Cheng, Xiaolong Wu, 2021, Frontiers in Endocrinology.

Regulation of blood-testis barrier dynamics: an in vivo study

C. Cheng, D. Mruk, W. Lui, 2004, Journal of Cell Science.

Two resveratrol analogs, pinosylvin and 4,4'-dihydroxystilbene, improve oligoasthenospermia in a mouse model by attenuating oxidative stress via the Nrf2-ARE pathway.

Mengmeng Sang, C. Cheng, Chengniu Wang, 2020, Bioorganic chemistry.

c-Yes regulates cell adhesion at the blood-testis barrier and the apical ectoplasmic specialization in the seminiferous epithelium of rat testes.

C. Cheng, D. Mruk, Xiang Xiao, 2011, The international journal of biochemistry & cell biology.

Environmental toxicants and male reproductive function

B. Silvestrini, P. Mathur, C. Cheng, 2011, Spermatogenesis.

Localization and molecular heterogeneity of sulfated glycoprotein-2 (clusterin) among ventral prostate, seminal vesicle, testis, and epididymis of rats.

M. Griswold, C. Cheng, C. Bardin, 1993, Biology of reproduction.

Sertoli-Germ Cell Anchoring Junction Dynamics in the Testis Are Regulated by an Interplay of Lipid and Protein Kinases*

C. Cheng, M. Siu, Ching-hang Wong, 2005, Journal of Biological Chemistry.

Structural analysis of clusterin and its subunits in ram rete testis fluid.

P. Mathur, C. Cheng, J. Grima, 1988, Biochemistry.

The biology of the desmosome-like junction a versatile anchoring junction and signal transducer in the seminiferous epithelium.

C. Cheng, P. Lie, D. Mruk, 2011, International review of cell and molecular biology.

Biology and Regulation of Blood-Tissue Barriers

C. Cheng, C. Cheng, 2014, Advances in Experimental Medicine and Biology.

F5-peptide and mTORC1/rpS6 effectively enhance BTB transport function in the testis - lesson from the adjudin model.

B. Silvestrini, Q. Lian, C. Cheng, 2019, Endocrinology.

Actin nucleator Spire 1 is a regulator of ectoplasmic specialization in the testis

B. Silvestrini, Q. Lian, C. Cheng, 2018, Cell Death & Disease.

F5-peptide induces aspermatogenesis by disrupting organization of actin- and microtubule-based cytoskeletons in the testis

C. Cheng, D. Mruk, W. Lui, 2016, Oncotarget.

Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells

C. Cheng, W. Lui, Ying Gao, 2016, Scientific Reports.

Planar Cell Polarity (PCP) Protein Vangl2 Regulates Ectoplasmic Specialization Dynamics via Its Effects on Actin Microfilaments in the Testes of Male Rats.

C. Cheng, D. Mruk, Haiqi Chen, 2016, Endocrinology.

Rai14 (Retinoic Acid Induced Protein 14) Is Involved in Regulating F-Actin Dynamics at the Ectoplasmic Specialization in the Rat Testis*

C. Cheng, D. Mruk, Yan-ho Cheng, 2013, PloS one.

Anchoring Junctions As Drug Targets: Role in Contraceptive Development

B. Silvestrini, C. Cheng, D. Mruk, 2008, Pharmacological Reviews.

Cross-talk between tight and anchoring junctions-lesson from the testis.

C. Cheng, D. Mruk, Helen H. N. Yan, 2008, Advances in experimental medicine and biology.

Title Ectoplasmic specialization : A friend or a foe ofspermatogenesis ?

C. Cheng, D. Mruk, Will M. Lee, 2008 .

Regulation of cell junction dynamics by cytokines in the testis: a molecular and biochemical perspective.

C. Cheng, W. Lui, C. Cheng, 2007, Cytokine & growth factor reviews.

Ectoplasmic specialization: a friend or a foe of spermatogenesis?

C. Cheng, D. Mruk, Helen H. N. Yan, 2007, BioEssays : news and reviews in molecular, cellular and developmental biology.

The Blood-Testis Barrier and Its Implications for Male Contraception

D. Sibley, C. Cheng, D. Mruk, 2012, Pharmacological Reviews.

Blood-Testis Barrier

Ming Yan, C. Cheng, Bai-ping Mao, 2014 .

Regulation of blood-testis barrier by actin binding proteins and protein kinases.

C. Cheng, E. Tang, Nan Li, 2016, Reproduction.

Biochemistry of Sertoli cell/germ cell junctions, germ cell transport, and spermiation in the seminiferous epithelium

C. Cheng, D. Mruk, C. Cheng, 2015 .

Focal adhesion kinase is a regulator of F-actin dynamics

C. Cheng, D. Mruk, Stephen Y. T. Li, 2013, Spermatogenesis.

Breast cancer resistance protein (Bcrp) and the testis--an unexpected turn of events.

C. Cheng, D. Mruk, Yan-ho Cheng, 2013, Asian journal of andrology.

RAI14 (retinoic acid induced protein 14) is an F-actin regulator

C. Cheng, D. Mruk, Yan-ho Cheng, 2013, Spermatogenesis.

Intercellular adhesion molecules (ICAMs) and spermatogenesis.

C. Cheng, D. Mruk, Xiang Xiao, 2013, Human reproduction update.

Drug transporters and blood--testis barrier function.

C. Cheng, D. Mruk, Linlin Su, 2011, The Journal of endocrinology.

A local autocrine axis in the testes that regulates spermatogenesis

C. Cheng, D. Mruk, C. Cheng, 2010, Nature Reviews Endocrinology.

Extracellular matrix and its role in spermatogenesis.

C. Cheng, M. Siu, C. Cheng, 2008, Advances in experimental medicine and biology.

mTORC1/rpS6 regulates blood-testis barrier dynamics and spermatogenetic function in the testis in vivo.

Ming Yan, C. Cheng, Haiqi Chen, 2018, American journal of physiology. Endocrinology and metabolism.

GENOMIC LEVEL IDENTIFICATION OF AUXIN RESPONSE FACTOR GENE FAMILY IN GNETUM

C. Cheng, Ong, Engfeng, 2020 .

Mitogenic activity and plasminogen activator in harvest fluid concentrates from mammary cells in culture.

C. Cheng, E. Howard, J. S. Howard, 1980, Cancer research.

Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis.

C. Cheng, D. Mruk, C. Cheng, 2004, Endocrine reviews.

TGF-betas: their role in testicular function and Sertoli cell tight junction dynamics.

C. Cheng, W. Lui, Will M. Lee, 2003, International journal of andrology.

Cell junction dynamics in the testis: Sertoli-germ cell interactions and male contraceptive development.

C. Cheng, D. Mruk, C. Cheng, 2002, Physiological reviews.

The Mammalian Blood-Testis Barrier: Its Biology and Regulation.

C. Cheng, D. Mruk, C. Cheng, 2015, Endocrine reviews.

Rat prostaglandin D2 synthetase: its tissue distribution, changes during maturation, and regulation in the testis and epididymis.

B. Silvestrini, C. Cheng, S. Chung, 1998, Biology of reproduction.

Whole-Exome Sequencing of a Large Chinese Azoospermia and Severe Oligospermia Cohort Identifies Novel Infertility Causative Variants and Genes.

Yong-tong Zhu, C. Cheng, Gui-Shuan Wang, 2020, Human molecular genetics.

Cytokines and junction restructuring during spermatogenesis--a lesson to learn from the testis.

C. Cheng, W. Xia, D. Mruk, 2005, Cytokine & growth factor reviews.

Ectoplasmic specialization, a testis-specific cell-cell actin-based adherens junction type: is this a potential target for male contraceptive development?

C. Cheng, Nikki P Y Lee, Nikki P. Y. Lee, 2004, Human reproduction update.

Indazole carboxylic acids in male contraception.

B. Silvestrini, C. Cheng, L. Saso, 2002, Contraception.

Toxicants target cell junctions in the testis: Insights from the indazole-carboxylic acid model

C. Cheng, C. Cheng, 2014, Spermatogenesis.

Adjudin, a potential male contraceptive, exerts its effects locally in the seminiferous epithelium of mammalian testes.

C. Cheng, P. Lie, D. Mruk, 2011, Reproduction.

A male contraceptive targeting germ cell adhesion

B. Silvestrini, C. Cheng, D. Mruk, 2006, Nature Medicine.

AF-2364 [1-(2,4-dichlorobenzyl)-1H-indazole-3-carbohydrazide] is a potential male contraceptive: a review of recent data.

B. Silvestrini, C. Cheng, D. Mruk, 2005, Contraception.

Inhibition of sperm capacitation and fertilizing capacity by adjudin is mediated by chloride and its channels in humans.

R. Ge, C. Cheng, Y. Ni, 2013, Human reproduction.

Lonidamine and Analogue AF2785 Block the Cyclic Adenosine 3′,5′-Monophosphate-Activated Chloride Current and Chloride Secretion in the Rat Epididymis1

B. Silvestrini, C. Cheng, P. Wong, 2000, Biology of reproduction.

Review Adherens Junction Dynamics in the Testis and Spermatogenesis Structure and Molecular Composition

C. Cheng, D. Mruk, W. Lui, 2022 .

Male Infertility in Humans: An Update on Non-obstructive Azoospermia (NOA) and Obstructive Azoospermia (OA).

C. Cheng, Xiaolong Wu, Dengfeng Lin, 2021, Advances in experimental medicine and biology.

Unraveling epigenomic abnormality in azoospermic human males by WGBS, RNA-Seq, and transcriptome profiling analyses

Jue Fan, C. Cheng, Xiaolong Wu, 2020, Journal of Assisted Reproduction and Genetics.

The apical ectoplasmic specialization-blood-testis barrier functional axis is a novel target for male contraception.

B. Silvestrini, P. Mathur, C. Cheng, 2012, Advances in experimental medicine and biology.

Disruption of Sertoli‐germ cell adhesion function in the seminiferous epithelium of the rat testis can be limited to adherens junctions without affecting the blood–testis barrier integrity: An in vivo study using an androgen suppression model

C. Cheng, W. Xia, Ching-hang Wong, 2005, Journal of cellular physiology.

Regulation of microtubule (MT)-based cytoskeleton in the seminiferous epithelium during spermatogenesis.

C. Cheng, D. Mruk, E. Tang, 2016, Seminars in cell & developmental biology.

Sertoli cell prostaglandin D2 synthetase is a multifunctional molecule: its expression and regulation.

B. Silvestrini, C. Cheng, J. Grima, 2000, Endocrinology.

Zyxin, axin, and Wiskott-Aldrich syndrome protein are adaptors that link the cadherin/catenin protein complex to the cytoskeleton at adherens junctions in the seminiferous epithelium of the rat testis.

C. Cheng, D. Mruk, Nikki P Y Lee, 2004, Journal of andrology.

Laminin α 3 Forms a Complex with β3 and γ3 Chains That Serves as the Ligand for α 6β1-Integrin at the Apical Ectoplasmic Specialization in Adult Rat Testes*

C. Cheng, Helen H. N. Yan, C. Cheng, 2006, Journal of Biological Chemistry.

Mammalian target of rapamycin controls glucose consumption and redox balance in human Sertoli cells.

M. Alves, M. Sousa, P. Oliveira, 2016, Fertility and sterility.

The Warburg Effect Revisited—Lesson from the Sertoli Cell

M. Alves, P. Oliveira, C. Cheng, 2015, Medicinal research reviews.

An intracellular trafficking pathway in the seminiferous epithelium regulating spermatogenesis: a biochemical and molecular perspective

C. Cheng, D. Mruk, C. Cheng, 2009, Critical reviews in biochemistry and molecular biology.

Nitric Oxide/Nitric Oxide Synthase, Spermatogenesis, and Tight Junction Dynamics1

C. Cheng, Nikki P Y Lee, Nikki P. Y. Lee, 2004, Biology of reproduction.

Abnormal glycosylation of α2-macroglobulin, a non-acute-phase protein, in patients with autoimmune diseases

B. Silvestrini, C. Cheng, A. Guglielmotti, 1993, Inflammation.

Development of an enzyme-linked immunosorbent assay with a monoclonal antibody prepared against alpha 1-antitrypsin for diagnostic screening of inflammatory disorders.

B. Silvestrini, C. Cheng, A. Guglielmotti, 1990, Clinical chemistry.

Cell-Cell Interaction-Mediated Signaling in the Testis Induces Reproductive Dysfunction—Lesson from the Toxicant/Pharmaceutical Models

C. Cheng, Chris K C Wong, Xiaolong Wu, 2022, Cells.

Rescue of PFOS-induced human Sertoli cell injury by overexpressing a p-FAK-Y407E phosphomimetic mutant

B. Silvestrini, C. Cheng, D. Mruk, 2017, Scientific Reports.

Perfluorooctanesulfonate (PFOS) perturbs male rat Sertoli cell blood-testis barrier function by affecting F-actin organization via p-FAK-Tyr(407): an in vitro study.

C. Cheng, C. Wong, D. Mruk, 2014, Endocrinology.

Rictor/mTORC2 regulates blood‐testis barrier dynamics via its effects on gap junction communications and actin filament network

C. Cheng, D. Mruk, Ka-Wai Mok, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Regulation of blood-testis barrier (BTB) dynamics during spermatogenesis via the "Yin" and "Yang" effects of mammalian target of rapamycin complex 1 (mTORC1) and mTORC2.

C. Cheng, D. Mruk, Ka-Wai Mok, 2013, International review of cell and molecular biology.

Role of cell polarity and planar cell polarity (PCP) proteins in spermatogenesis

Huitao Li, C. Cheng, R. Ge, 2020, Critical reviews in biochemistry and molecular biology.

Cell polarity proteins and spermatogenesis.

C. Cheng, D. Mruk, W. Lui, 2016, Seminars in cell & developmental biology.

Mitogen-activated protein kinases in male reproductive function.

C. Cheng, D. Mruk, Michelle W. M. Li, 2009, Trends in molecular medicine.

Unraveling the Regulation of Cancer/Testis Antigens in Tumorigenesis Through an Analysis of Normal Germ Cell Development in Rodents.

C. Cheng, D. Mruk, Haiqi Chen, 2021, Advances in experimental medicine and biology.

Transcriptional regulation of cell adhesion at the blood-testis barrier and spermatogenesis in the testis.

C. Cheng, W. Lui, C. Cheng, 2012, Advances in experimental medicine and biology.

Adjudin attenuates lipopolysaccharide (LPS)- and ischemia-induced microglial activation

B. Silvestrini, C. Cheng, W. Xia, 2013, Journal of Neuroimmunology.

NC1-peptide from collagen α3 (IV) chains in the basement membrane of testes regulates spermatogenesis via p-FAK-Y407.

Shiwen Liu, Huitao Li, C. Cheng, 2020, Endocrinology.

Coordination of Actin- and Microtubule-Based Cytoskeletons Supports Transport of Spermatids and Residual Bodies/Phagosomes During Spermatogenesis in the Rat Testis.

C. Cheng, E. Tang, Will M. Lee, 2016, Endocrinology.

EB1 regulates tubulin and actin cytoskeletal networks at the sertoli cell blood-testis barrier in male rats: an in vitro study.

C. Cheng, Ka-Wai Mok, E. Tang, 2015, Endocrinology.

Environmental toxicants perturb human Sertoli cell adhesive function via changes in F-actin organization mediated by actin regulatory proteins.

B. Silvestrini, C. Cheng, D. Mruk, 2014, Human reproduction.

Focal adhesion kinase-Tyr407 and -Tyr397 exhibit antagonistic effects on blood–testis barrier dynamics in the rat

C. Cheng, P. Lie, D. Mruk, 2012, Proceedings of the National Academy of Sciences.

Regulation of spermiogenesis, spermiation and blood-testis barrier dynamics: novel insights from studies on Eps8 and Arp3.

C. Cheng, D. Mruk, C. Cheng, 2011, The Biochemical journal.

The β1-integrin-p-FAK-p130Cas-DOCK180-RhoA-vinculin is a novel regulatory protein complex at the apical ectoplasmic specialization in adult rat testes

C. Cheng, W. Xia, D. Mruk, 2011, Spermatogenesis.

Restricted Arp3 expression in the testis prevents blood–testis barrier disruption during junction restructuring at spermatogenesis

C. Cheng, P. Lie, D. Mruk, 2010, Proceedings of the National Academy of Sciences.

Epidermal growth factor receptor pathway substrate 8 (Eps8) is a novel regulator of cell adhesion and the blood‐testis barrier integrity in the seminiferous epithelium

C. Cheng, P. Lie, D. Mruk, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Rho GTPases and spermatogenesis.

C. Cheng, W. Lui, Will M. Lee, 2003, Biochimica et biophysica acta.

Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development

Yi-Xun Liu, C. Cheng, Yuqian Wang, 2016, PloS one.

Cell–cell interactions at the ectoplasmic specialization in the testis

C. Cheng, D. Mruk, C. Cheng, 2004, Trends in Endocrinology & Metabolism.

Cloning and characterization of a novel nuclear Bcl-2 family protein, zfMcl-1a, in zebrafish embryo.

Jiann-Ruey Hong, C. Cheng, H. Gong, 2000, Biochemical and biophysical research communications.

Adaptors, Junction Dynamics, and Spermatogenesis1

C. Cheng, Nikki P Y Lee, Yan-ho Cheng, 2004, Biology of reproduction.

High Throughput scRNA-Seq Provides Insights Into Leydig Cell Senescence Induced by Experimental Autoimmune Orchitis: A Prominent Role of Interstitial Fibrosis and Complement Activation

Weibing Qin, Yunge Tang, C. Cheng, 2022, Frontiers in Immunology.

Tex13a Optimizes Sperm Motility via Its Potential Roles in mRNA Turnover

Weibing Qin, Yunge Tang, C. Cheng, 2021, Frontiers in Cell and Developmental Biology.

Differential Interactions between Transforming Growth Factor-β3/TβR1, TAB1, and CD2AP Disrupt Blood-Testis Barrier and Sertoli-Germ Cell Adhesion*

C. Cheng, W. Xia, D. Mruk, 2006, Journal of Biological Chemistry.

Human obstructive (postvasectomy) and nonobstructive azoospermia – Insights from scRNA-Seq and transcriptome analysis

Jue Fan, C. Cheng, G. An, 2020, Genes & diseases.

Single cell ATAC-Seq reveals cell type-specific transcriptional regulation and unique chromatin accessibility in human spermatogenesis.

C. Cheng, E. Duan, Xiaolong Wu, 2021, Human molecular genetics.

Intercellular adhesion molecule 1: recent findings and new concepts involved in mammalian spermatogenesis.

C. Cheng, D. Mruk, B. Bilińska, 2014, Seminars in cell & developmental biology.

Jcb: Mini-review Introduction

E. Ferber, C. Cheng, F. Pichaud, 2022 .

Transport of germ cells across the seminiferous epithelium during spermatogenesis—the involvement of both actin- and microtubule-based cytoskeletons

B. Silvestrini, C. Cheng, D. Mruk, 2016, Tissue barriers.

Germ cell transport across the seminiferous epithelium during spermatogenesis.

C. Cheng, D. Mruk, Chris K C Wong, 2014, Physiology.

Biology and regulation of ectoplasmic specialization, an atypical adherens junction type, in the testis.

C. Cheng, E. W. Wong, D. Mruk, 2008, Biochimica et biophysica acta.

Mammalian target of rapamycin (mTOR): a central regulator of male fertility?

M. Alves, M. Sousa, P. Oliveira, 2017, Critical reviews in biochemistry and molecular biology.

Motor Proteins and Spermatogenesis.

Huitao Li, C. Cheng, R. Ge, 2021, Advances in experimental medicine and biology.

Emerging Role for SRC family kinases in junction dynamics during spermatogenesis.

C. Cheng, Yue Yang, Bai-ping Mao, 2019, Reproduction.

Regulation of Blood-Testis Barrier (BTB) Dynamics, Role of Actin-, and Microtubule-Based Cytoskeletons.

B. Silvestrini, C. Cheng, D. Mruk, 2018, Methods in molecular biology.

Formin 1 Regulates Microtubule and F-Actin Organization to Support Spermatid Transport During Spermatogenesis in the Rat Testis.

C. Cheng, D. Mruk, Chris K C Wong, 2016, Endocrinology.

Formin 1 Regulates Ectoplasmic Specialization in the Rat Testis Through Its Actin Nucleation and Bundling Activity.

Daishu Han, C. Cheng, D. Mruk, 2015, Endocrinology.

Enhanced chemiluminescence (ECL) for routine immunoblotting

C. Cheng, D. Mruk, C. Cheng, 2011, Spermatogenesis.

Emerging role for drug transporters at the blood-testis barrier.

C. Cheng, D. Mruk, Linlin Su, 2011, Trends in pharmacological sciences.

Sertoli–germ cell junctions in the testis: a review of recent data

C. Cheng, D. Mruk, B. Bilińska, 2010, Philosophical Transactions of the Royal Society B: Biological Sciences.

Cellular senescence involves stochastic processes causing loss of expression of differentiated function genes: transfection with SV40 as a means for dissociating effects of senescence on growth and on differentiated function gene expression.

C. Cheng, P. Hornsby, R. F. Ryan, 1989, Experimental cell research.

Basement Membrane Laminin &agr;2 Regulation of BTB Dynamics via Its Effects on F-Actin and Microtubule Cytoskeletons Is Mediated Through mTORC1 Signaling

C. Cheng, Haiqi Chen, W. Lui, 2017, Endocrinology.

Overexpression of plastin 3 in Sertoli cells disrupts actin microfilament bundle homeostasis and perturbs the tight junction barrier

C. Cheng, Nan Li, Will M. Lee, 2016, Spermatogenesis.

Plastins regulate ectoplasmic specialization via its actin bundling activity on microfilaments in the rat testis

C. Cheng, Chris K C Wong, Nan Li, 2015, Asian journal of andrology.

Formins: Actin nucleators that regulate cytoskeletal dynamics during spermatogenesis

B. Silvestrini, C. Cheng, D. Mruk, 2015, Spermatogenesis.

Actin binding proteins in blood-testis barrier function.

C. Cheng, D. Mruk, Nan Li, 2015, Current opinion in endocrinology, diabetes, and obesity.

Differential effects of c-Src and c-Yes on the endocytic vesicle-mediated trafficking events at the Sertoli cell blood-testis barrier: an in vitro study.

Daishu Han, C. Cheng, E. W. Wong, 2014, American journal of physiology. Endocrinology and metabolism.

Cytokines, polarity proteins, and endosomal protein trafficking and signaling-the sertoli cell blood-testis barrier system in vitro as a study model.

C. Cheng, P. Lie, E. W. Wong, 2014, Methods in enzymology.

MAP/microtubule affinity-regulating kinases, microtubule dynamics, and spermatogenesis.

C. Cheng, D. Mruk, E. Tang, 2013, The Journal of endocrinology.

Actin cross-linking protein palladin and spermatogenesis

C. Cheng, D. Mruk, Yan-ho Cheng, 2013, Spermatogenesis.

A peptide derived from laminin-γ3 reversibly impairs spermatogenesis in rats

B. Silvestrini, C. Cheng, P. Lie, 2012, Nature Communications.

Interactions of Proteases, Protease Inhibitors, and the β1 Integrin/Laminin γ3 Protein Complex in the Regulation of Ectoplasmic Specialization Dynamics in the Rat Testis1

C. Cheng, M. Siu, C. Cheng, 2004, Biology of reproduction.

Vangl2 regulates spermatid planar cell polarity through microtubule (MT)-based cytoskeleton in the rat testis

C. Cheng, Haiqi Chen, W. Lui, 2018, Cell Death & Disease.

N-WASP Is Required for Structural Integrity of the Blood-Testis Barrier

B. Shilo, S. Snapper, E. Schejter, 2014, PLoS genetics.

Intercellular adhesion molecule-2 is involved in apical ectoplasmic specialization dynamics during spermatogenesis in the rat

C. Cheng, D. Mruk, Xiang Xiao, 2012, The Journal of endocrinology.

A study to assess the assembly of a functional blood-testis barrier in developing rat testes

C. Cheng, D. Mruk, Ka-Wai Mok, 2011, Spermatogenesis.

Interactions of laminin β3 fragment with β1-integrin receptor

P. Mathur, C. Cheng, P. Lie, 2011, Spermatogenesis.

Regulation of blood-testis barrier dynamics by desmosome, gap junction, hemidesmosome and polarity proteins

B. Silvestrini, P. Mathur, C. Cheng, 2011, Spermatogenesis.

Crosstalk between desmoglein-2/desmocollin-2/Src kinase and coxsackie and adenovirus receptor/ZO-1 protein complexes, regulates blood-testis barrier dynamics.

C. Cheng, P. Lie, D. Mruk, 2010, The international journal of biochemistry & cell biology.

Planar cell polarity protein Dishevelled 3 (Dvl3) regulates ectoplasmic specialization (ES) dynamics in the testis through changes in cytoskeletal organization

Ming Yan, Q. Lian, C. Cheng, 2019, Cell Death & Disease.

Actin binding proteins, spermatid transport and spermiation.

Daishu Han, C. Cheng, E. W. Wong, 2014, Seminars in cell & developmental biology.

Regulation of the blood-testis barrier by coxsackievirus and adenovirus receptor.

C. Cheng, D. Mruk, Linlin Su, 2012, American journal of physiology. Cell physiology.

Ability of trypsin in mimicking germ cell factors that affect Sertoli cell secretory function

C. Cheng, C. Bardin, G. R. Aravindan, 1996, Journal of cellular physiology.

Germ cells contribute to the function of the Sertoli cell barrier

C. Cheng, D. Mruk, B. Bilińska, 2013 .

Title Thyroid Hormone Function in the Rat Testis

C. Cheng, Ying Gao, Will M. Lee, 2014 .

Perfluorooctanesulfonate (PFOS)-induced Sertoli cell injury through a disruption of F-actin and microtubule organization is mediated by Akt1/2

C. Cheng, D. Mruk, Haiqi Chen, 2017, Scientific Reports.

Connexin 43 is critical to maintain the homeostasis of the blood–testis barrier via its effects on tight junction reassembly

C. Cheng, D. Mruk, Michelle W. M. Li, 2010, Proceedings of the National Academy of Sciences.

Transforming Growth Factor β3 Regulates the Dynamics of Sertoli Cell Tight Junctions Via the p38 Mitogen-Activated Protein Kinase Pathway1

C. Cheng, W. Lui, Will M. Lee, 2003, Biology of reproduction.

An occludin-focal adhesion kinase protein complex at the blood-testis barrier: a study using the cadmium model.

C. Cheng, C. Porto, E. W. Wong, 2009, Endocrinology.

Transforming growth factor beta3 regulates the dynamics of Sertoli cell tight junctions via the p38 mitogen-activated protein kinase pathway.

C. Cheng, W. Lui, Will M. Lee, 2003, Biology of reproduction.

The role of the carbohydrate moiety on the size heterogeneity and immunologic determinants of human testosterone-estradiol-binding globulin.

C. Cheng, C. Bardin, G. Gunsalus, 1985, Journal of steroid biochemistry.

Identification of protein A-binding components in Spisula oocytes.

C. Cheng, L. Yang, S. Koide, 1994, Life sciences.

Sperm epigenetic alterations contribute to inter- and transgenerational effects of paternal exposure to long-term psychological stress via evading offspring embryonic reprogramming

Fei Sun, C. Cheng, Gui-Shuan Wang, 2021, Cell Discovery.

Sperm epigenetic alterations contribute to inter- and transgenerational effects of paternal exposure to long-term psychological stress via evading offspring embryonic reprogramming

C. Cheng, Gui-Shuan Wang, F. Sun, 2021, Cell Discovery.

Testin Is Tightly Associated with Testicular Cell Membrane upon Its Secretion by Sertoli Cells whose Steady-state mRNA Level in the Testis Correlates with the Turnover and Integrity of Inter-testicular Cell Junctions*

C. Cheng, J Grima, L Zhu, 1997, The Journal of Biological Chemistry.

Planar cell polarity (PCP) proteins and spermatogenesis.

C. Cheng, Haiqi Chen, C. Cheng, 2016, Seminars in cell & developmental biology.

Changes in gene expression and DNA methylation in adrenocortical cells senescing in culture.

C. Cheng, P. Hornsby, L. Yang, 1991, Mutation research.

Astrocytes cultured in vitro produce estradiol-17beta and express aromatase cytochrome P-450 (P-450 AROM) mRNA.

C. Cheng, S. Yen, I. Zwain, 1997, Biochimica et Biophysica Acta.

Claudin and occludin expression and function in the seminiferous epithelium

C. Cheng, D. Mruk, R. Hess, 2010, Philosophical Transactions of the Royal Society B: Biological Sciences.

Spermatogenesis : Biology and Clinical Implications

C. Cheng, 2018 .

Interleukin 1 Alpha (IL1A) Is a Novel Regulator of the Blood-Testis Barrier in the Rat1

P. Mathur, C. Cheng, D. Mruk, 2008, Biology of reproduction.

The apical ES-BTB-BM functional axis is an emerging target for toxicant-induced infertility.

C. Cheng, D. Mruk, Chris K C Wong, 2013, Trends in molecular medicine.

Erratum: Perfluorooctanesulfonate (PFOS)-induced Sertoli cell injury through a disruption of F-actin and microtubule organization is mediated by Akt1/2

C. Cheng, D. Mruk, Haiqi Chen, 2017, Scientific Reports.

The differential effects of the indazole-carboxylic acid derivative, tolnidamine, on Sertoli cell protein secretion.

C. Cheng, C. Bardin, G. Gunsalus, 1989, Journal of andrology.

Antioxidant superoxide dismutase - a review: its function, regulation in the testis, and role in male fertility.

B. Silvestrini, C. Cheng, D. Mruk, 2002, Contraception.

Role of tissue inhibitor of metalloproteases-1 in junction dynamics in the testis.

C. Cheng, D. Mruk, M. Siu, 2003, Journal of andrology.

The biology of spermatogenesis: the past, present and future

C. Cheng, D. Mruk, C. Cheng, 2010, Philosophical Transactions of the Royal Society B: Biological Sciences.

Regulation of Sertoli cell tight junction dynamics in the rat testis via the nitric oxide synthase/soluble guanylate cyclase/3',5'-cyclic guanosine monophosphate/protein kinase G signaling pathway: an in vitro study.

C. Cheng, Nikki P. Y. Lee, C. Cheng, 2003, Endocrinology.

Polarity proteins and cell-cell interactions in the testis.

C. Cheng, E. W. Wong, C. Cheng, 2009, International review of cell and molecular biology.

Polarity protein complex Scribble/Lgl/Dlg and epithelial cell barriers.

C. Cheng, E. W. Wong, D. Mruk, 2012, Advances in experimental medicine and biology.

Role of non-receptor protein tyrosine kinases in spermatid transport during spermatogenesis.

C. Cheng, E. W. Wong, D. Mruk, 2014, Seminars in cell & developmental biology.

Nonreceptor Protein Kinases c-Src, c-Yes, and FAK Are Biomarkers for Male Contraceptive Research

B. Silvestrini, P. Jenardhanan, P. Mathur, 2013 .

Two New Male Contraceptives Exert Their Effects by Depleting Germ Cells Prematurely from the Testis1

B. Silvestrini, M. Palmery, C. Cheng, 2001, Biology of reproduction.

Male germ cells support long-term propagation of Zika virus

C. Cheng, Shuibing Chen, Mohsan Saeed, 2018, Nature Communications.

Regulation of BTB dynamics in spermatogenesis - insights from the adjudin toxicant model.

Ming Yan, Q. Lian, C. Cheng, 2019, Toxicological sciences : an official journal of the Society of Toxicology.

Regulation of BTB Dynamics in Spermatogenesis—Insights From the Adjudin Model

Ming Yan, C. Cheng, R. Ge, 2019 .

Male contraceptive Adjudin is a potential anti-cancer drug.

B. Silvestrini, C. Cheng, Jian Yang, 2013, Biochemical pharmacology.

An in vivo study on adjudin and blood-testis barrier dynamics.

C. Cheng, D. Mruk, B. Bilińska, 2009, Endocrinology.

Adjudin targeting rabbit germ cell adhesion as a male contraceptive: a pharmacokinetics study.

B. Silvestrini, R. Ge, C. Cheng, 2008, Journal of andrology.

Unraveling the molecular targets pertinent to junction restructuring events during spermatogenesis using the Adjudin-induced germ cell depletion model.

C. Cheng, W. Xia, D. Mruk, 2007, The Journal of endocrinology.

Cellular localization of sphingomyelin synthase 2 in the seminiferous epithelium of adult rat testes.

C. Cheng, W. Xia, D. Mruk, 2007, The Journal of endocrinology.

Review article Indazole carboxylic acids in male contraception

B. Silvestrini, C. Cheng, L. Saso, 2002 .

Testin Induction: The Role of Cyclic 3′,5′-Adenosine Monophosphate/Protein Kinase A Signaling in the Regulation of Basal and Lonidamine-Induced Testin Expression by Rat Sertoli Cells1

C. Cheng, J. Grima, C. Cheng, 2000, Biology of reproduction.

Interactions of proteases and protease inhibitors in Sertoli-germ cell cocultures preceding the formation of specialized Sertoli-germ cell junctions in vitro.

B. Silvestrini, C. Cheng, D. Mruk, 1997, Journal of andrology.

Differential expression of multiple cathepsin mRNAs in the rat testis during maturation and following lonidamine induced tissue restructuring

B. Silvestrini, P. Mathur, C. Cheng, 1997, Biochemistry and molecular biology international.

Immunohistochemical localization of testin in the female reproductive system of the rat is consistent with its involvement in the turnover of specialized junctional complexes.

C. Cheng, C. Bardin, A. Moo-Young, 1997, Biology of reproduction.

Purification of a candidate gonadotropin surge inhibiting factor from porcine follicular fluid.

C. Cheng, D. Danforth, C. Cheng, 1995, Endocrinology.

Cyclic and postnatal developmental changes of testin in the rat seminiferous epithelium--an immunohistochemical study.

C. Cheng, C. Bardin, J. Grima, 1994, Biology of reproduction.

Testins are structurally related to the mouse cysteine proteinase precursor but devoid of any protease/anti-protease activity.

C. Cheng, C. Bardin, I. Morris, 1993, Biochemical and biophysical research communications.

Drug transporters, the blood-testis barrier, and spermatogenesis.

C. Cheng, D. Mruk, Linlin Su, 2010, The Journal of endocrinology.

Spermiation: Insights from Studies on the Adjudin Model.

C. Cheng, D. Mruk, Haiqi Chen, 2021, Advances in experimental medicine and biology.

The biology of interleukin-1: emerging concepts in the regulation of the actin cytoskeleton and cell junction dynamics

C. Cheng, P. Lie, D. Mruk, 2011, Cellular and Molecular Life Sciences.

Purification of gonadotropin surge-inhibiting factor from Sertoli cell-enriched culture medium.

C. Cheng, C. Bardin, D. Koppenaal, 1994, Biochemical and biophysical research communications.

HIV-1 establishes a sanctuary site in the testis by permeating the BTB through changes in cytoskeletal organization.

C. Cheng, E. Martinelli, I. Frank, 2021, Endocrinology.

Interleukin 1 Alpha (IL1A) Is a Novel Regulator of the Blood-Testis Barrier in the Rat 1

P. Mathur, C. Cheng, D. Mruk, 2008 .

Rat testicular extracellular superoxide dismutase: its purification, cellular distribution, and regulation.

B. Silvestrini, C. Cheng, D. Mruk, 1998, Biology of reproduction.

Quantification of prostaglandin D synthetase in cerebrospinal fluid: A potential marker for brain tumor

B. Silvestrini, E. Samy, C. Cheng, 1998, Biochemistry and molecular biology international.

Micropurification of Two Human Cerebrospinal Fluid Proteins by High Performance Electrophoresis Chromatography

B. Silvestrini, C. Cheng, L. Saso, 1993, Journal of neurochemistry.

NC1‐peptide regulates spermatogenesis through changes in cytoskeletal organization mediated by EB1

Shiwen Liu, Huitao Li, C. Cheng, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Corticosteroid binding globulin, testosterone-estradiol binding globulin, and androgen binding protein belong to protein families distinct from steroid receptors.

C. Cheng, G. Hammond, J. Reventós, 1988, Journal of steroid biochemistry.

Changes in the expression of junctional and nonjunctional complex component genes when inter-sertoli tight junctions are formed in vitro.

C. Cheng, D. Mruk, S. Chung, 2000, Journal of andrology.

Sphingomyelin synthases and testicular function

C. Cheng, E. W. Wong, D. Mruk, 2008, Expert review of endocrinology & metabolism.

14-3-3 and its binding partners are regulators of protein-protein interactions during spermatogenesis.

C. Cheng, E. W. Wong, Shengyi Sun, 2009, The Journal of endocrinology.

rpS6 Regulates blood-testis barrier dynamics by affecting F-actin organization and protein recruitment.

B. Silvestrini, C. Cheng, D. Mruk, 2012, Endocrinology.

Printed in U.S.A. Copyright © 2001 by The Endocrine Society Is Cadmium Chloride-Induced Inter-Sertoli Tight Junction Permeability Barrier Disruption a Suitable in Vitro Model to Study the Events of Junction Disassembly during Spermatogenesis in the Rat Te

C. Cheng, N. Chung, 2022 .

Identification of hormonally responsive proteins in primary Sertoli cell culture medium by anion-exchange high performance liquid chromatography.

C. Cheng, C. Bardin, C W Bardin, 1986, Endocrinology.

Intercellular adhesion molecule-1 is a regulator of blood–testis barrier function

C. Cheng, D. Mruk, Xiang Xiao, 2012, Journal of Cell Science.

Micropurification of β- and γ-crystallins from rabbit aqueous humor

B. Silvestrini, C. Cheng, L. Saso, 1999 .

Astrocytes synthesize and secrete prostaglandin D synthetase in vitro.

B. Silvestrini, C. Cheng, S. Giacomelli, 1996, Biochimica et biophysica acta.

Melatonin promotes sheep Leydig cell testosterone secretion in a co-culture with Sertoli cells.

Chawnshang Chang, Yi-Xun Liu, C. Cheng, 2018, Theriogenology.

Gap junctions and blood-tissue barriers.

C. Cheng, D. Mruk, Michelle W. M. Li, 2012, Advances in experimental medicine and biology.

Sertolin mediates blood-testis barrier restructuring.

C. Cheng, D. Mruk, Michelle W. M. Li, 2014, Endocrinology.

Evidence for cross-talk between Sertoli and germ cells using selected cathepsins as markers.

B. Silvestrini, C. Cheng, S. Chung, 1998, Journal of andrology.

Regulation of drug transporters in the testis by environmental toxicant cadmium, steroids and cytokines

C. Cheng, D. Mruk, Linlin Su, 2012, Spermatogenesis.

Signaling pathways regulating blood-tissue barriers - Lesson from the testis.

B. Silvestrini, Yi-Xun Liu, C. Cheng, 2018, Biochimica et biophysica acta. Biomembranes.

Microtubule affinity-regulating kinase 4 (MARK4) is a component of the ectoplasmic specialization in the rat testis

P. Jenardhanan, P. Mathur, C. Cheng, 2012, Spermatogenesis.

Effects of lonidamine on testicular and epididymal proteins in the rat.

D. Guidolin, B. Silvestrini, C. Cheng, 2000, Reproductive toxicology.

Differential changes in alpha2-macroglobulin and hemopexin in brain and liver in response to acute inflammation.

B. Silvestrini, C. Cheng, L. Saso, 1999, Biochemistry. Biokhimiia.

Rat testicular testibumin is identical to sulfated glycoprotein-1 (SGP-1) whose mRNA expression in the testis is age- but not germ cell-dependent.

B. Silvestrini, P. Mathur, C. Cheng, 1994, Biochemistry and molecular biology international.

Response of alpha 2-macroglobulin messenger ribonucleic acid expression to acute inflammation in the testis is different from the response in the liver and brain.

C. Pineau, B. Silvestrini, C. Cheng, 1994, Biology of reproduction.

α2‐Macroglobulin: A Multifunctional Protein of the Seminiferous Tubule a

C. Cheng, C. Bardin, G. Verhoeven, 1991 .

Alpha 2-macroglobulin is not an acute-phase protein in the rat testis.

B. Silvestrini, C. Cheng, C. Bardin, 1991, Endocrinology.

Changes in concanavalin A-reactive proteins in inflammatory disorders.

B. Silvestrini, C. Cheng, A. Guglielmotti, 1989, Clinical chemistry.

TGF-beta3 regulates the blood-testis barrier dynamics via the p38 mitogen activated protein (MAP) kinase pathway: an in vivo study.

C. Cheng, D. Mruk, W. Lui, 2003, Endocrinology.

Experience with 19-nortestosterone in the therapy of systemic lupus erythematosus: worsened disease after treatment with 19-nortestosterone in men and lack of improvement in women.

C. Cheng, C. Bardin, R. Lahita, 1992, The Journal of rheumatology.