D. Hill

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Offspring of Mice Exposed to a Low-Protein Diet in Utero Demonstrate Changes in mTOR Signaling in Pancreatic Islets of Langerhans, Associated with Altered Glucagon and Insulin Expression and a Lower β-Cell Mass

N. Morgan, S. Richardson, Yuzhen Tong, 2019, Nutrients.

Apoptosis in the pancreatic islet cells of the neonatal rat is associated with a reduced expression of insulin-like growth factor II that may act as a survival factor.

J. Petrik, D. Hill, T. McDonald, 1998, Endocrinology.

Modulation of insulin-like growth factor (IGF) and IGF binding protein biosynthesis by hypoxia in cultured vascular endothelial cells.

V. Han, D. Hill, H. Farber, 1998, The Journal of endocrinology.

Growth factors and goitrogenesis.

D. Hill, S. Bidey, M. Eggo, 1999, The Journal of endocrinology.

Restriction of patching of bound concanavalin A after incorporation of arachidonic acid into the plasma membrane of virally transformed fibroblasts

D. Hill, J. Borysenko, 1979, The Journal of cell biology.

Increased levels of serum fibroblast growth factor-2 in diabetic pregnant women with retinopathy.

D. Hill, A. Flyvbjerg, E. Arany, 1997, The Journal of clinical endocrinology and metabolism.

Impact of the exposome on the development and function of pancreatic β-cells.

D. Hill, 2021, Molecular aspects of medicine.

GH in the dwarf dopaminergic D2 receptor knockout mouse: somatotrope population, GH release, and responsiveness to GH-releasing factors and somatostatin.

M. Low, M. Rubinstein, D. Hill, 2006, The Journal of endocrinology.

Growth factors and their cellular actions.

D. Hill, 1989, Journal of reproduction and fertility.

Immunological distribution of one form of insulin-like growth factor (IGF)-binding protein and IGF peptides in human fetal tissues.

D. Clemmons, V. Han, D. Hill, 1989, Journal of molecular endocrinology.

Localization of the growth hormone receptor, identified by immunocytochemistry, in second trimester human fetal tissues and in placenta throughout gestation.

M. Waters, D. Hill, S. Riley, 1992, The Journal of clinical endocrinology and metabolism.

Intra-uterine programming of the endocrine pancreas.

D. Hill, A. Fowden, D. J. Hill, 2001, British medical bulletin.

Balance of islet cell birth and death of fetal and neonatal rats is altered by a low protein diet through mechanisms which include cell cycle kinetics

B. Reusens, C. Remacle, J. Petrik, 1998 .

Somatomedin activity and growth hormone levels in body fluids of the fetal pig: effect of chronic hyperinsulinaemia.

D. Hill, B. Colenbrander, A. Macdonald, 1983, The Journal of endocrinology.

Human placenta and fetal membranes contain peptide YY1-36 and peptide YY3-36.

D. Hill, T. McDonald, J. Challis, 1998, The Journal of endocrinology.

Basic fibroblast growth factor (basic FGF) in isolated ovine thyroid follicles: thyrotropin stimulation and effects of basic FGF on DNA synthesis, iodine uptake and organification, and the release of insulin-like growth factors (IGFs) and IGF-binding proteins.

D. Hill, I. Phillips, J. Wang, 1994, Thyroid : official journal of the American Thyroid Association.

Cell Cycle-Dependent Localization of Irnmunoreactive Basic Fibroblast Growth Factor to Cytoplasm and Nucleus of Isolated Ovine Fetal Growth Plate Chondrocytes

D. Hill, A. Logan, 1992 .

Basic fibroblast growth factor is synthesized and released by isolated ovine fetal growth plate chondrocytes: potential role as an autocrine mitogen.

D. Hill, A. Logan, A. González, 1992, Growth factors.

Lineage tracing and resulting phenotype of haemopoietic-derived cells in the pancreas during beta cell regeneration

A. Chamson-Reig, D. Hill, E. Arany, 2010, Diabetologia.

Development of the Endocrine Pancreas

D. Hill, 2005, Reviews in Endocrine and Metabolic Disorders.

A mouse model of gestational glucose intolerance through exposure to a low protein diet during fetal and neonatal development

Renee T King, B. Strutt, D. Hill, 2019, The Journal of physiology.

Exposure of the Pregnant Rat to Low Protein Diet Causes Impaired Glucose Homeostasis in the Young Adult Offspring by Different Mechanisms in Males and Females

A. Chamson-Reig, D. Hill, E. Arany, 2009, Experimental biology and medicine.

Nutritional programming of pancreatic β-cell plasticity.

D. Hill, 2011, World journal of diabetes.

Insulin‐Like Growth Factors

D. Hill, 2002 .

Increased and persistent circulating insulin-like growth factor II in neonatal transgenic mice suppresses developmental apoptosis in the pancreatic islets.

B. Strutt, D. Hill, S. Zaina, 2000, Endocrinology.

Expression and release of insulin‐like growth factor binding proteins in isolated epiphyseal growth plate chondrocytes from the ovine fetus

P. De Los Rios, D. Hill, D. Hill, 2000, Journal of cellular physiology.

Cellular localization and expression of insulin-like growth factors (IGFs) and IGF binding proteins within the epiphyseal growth plate of the ovine fetus: possible functional implications.

P. De Los Rios, D. Hill, D. J. Hill, 1999, Canadian journal of physiology and pharmacology.

Models for understanding early human development

D. Hill, 1999 .

Overexpression of insulin-like growth factor-II in transgenic mice is associated with pancreatic islet cell hyperplasia.

W. Reik, W. Dean, J. Petrik, 1999, Endocrinology.

D. Clemmons, D. Hill, 1992, Growth factors.

FETAL GROWTH CONTROL: THE ROLE OF INSULIN AND RELATED PEPTIDES

D. Hill, R. Milner, 1984, Clinical endocrinology.

High plasma insulin-like growth factor-II and low lipid content in transgenic mice: measurements of lipid metabolism.

I. Robinson, D. Hill, D. Williamson, 1994, The Journal of endocrinology.

Increased islet neogenesis without increased islet mass precedes autoimmune attack in diabetes-prone rats

D. Hill, F. Scott, L. Kauri, 2007, Laboratory Investigation.

Extracellular nucleotides act through P2U purinoceptors to elevate [Ca2+]i and enhance basic fibroblast growth factor-induced proliferation in sheep chondrocytes.

S. Dixon, D. Hill, A. Kaplan, 1996, Endocrinology.

Growth factors and the regulation of fetal growth.

J. Petrik, D. Hill, E. Arany, 1998, Diabetes care.

Impaired vascular function in obese adolescents with insulin resistance.

D. Hill, M. Cuerden, C. Clarson, 2009, The Journal of pediatrics.

Neonatal Nutrition: Metabolic Programming of Pancreatic Islets and Obesity1

S. G. Laychock, D. Hill, M. Srinivasan, 2003, Experimental biology and medicine.

Increased Islet Cell Proliferation, Decreased Apoptosis, and Greater Vascularization Leading to β-Cell Hyperplasia in Mutant Mice Lacking Insulin.

D. Hill, R. Joshi, D. Bucchini, 2002, Endocrinology.

Spatial and temporal changes in the insulin-like growth factor (IGF) axis indicate autocrine/paracrine actions of IGF-I within wounds of the rat brain.

D. Hill, M. Berry, A. Logan, 1997, Endocrinology.

Taurine supplementation of a low protein diet fed to rat dams normalizes the vascularization of the fetal endocrine pancreas.

B. Reusens, C. Remacle, D. Hill, 2003, The Journal of nutrition.

Cellular mechanisms underlying failed beta cell regeneration in offspring of protein-restricted pregnant mice

D. Hill, E. Arany, D. Carter, 2013, Experimental biology and medicine.

Low-protein diet during early life causes a reduction in the frequency of cells immunopositive for nestin and CD34 in both pancreatic ducts and islets in the rat.

B. Reusens, D. Hill, E. Arany, 2004, Endocrinology.

REVIEW ARTICLE Pancreatic Development and Adult Diabetes

D. Hill, 2000 .

Gastrin-releasing peptide-like immunoreactivity is present in human maternal and fetal placental membranes.

D. Hill, E. Spindel, T. McDonald, 1996, The Journal of clinical endocrinology and metabolism.

Differential cellular synthesis of insulin-like growth factor binding protein-1 (IGFBP-1) and IGFBP-3 within human liver.

S. Afford, M. Arthur, D. Hill, 1994, The Journal of clinical endocrinology and metabolism.

Maternal protein restriction permanently programs adipocyte growth and development in adult male rat offspring

D. Hill, E. Arany, H. Guan, 2007, Journal of cellular biochemistry.

Altered pancreatic morphology in the offspring of pregnant rats given reduced dietary protein is time and gender specific.

A. Chamson-Reig, D. Hill, E. Arany, 2006, The Journal of endocrinology.

Tissue and serum insulin-like growth factor I (IGF I) concentrations in rats subjected to temporary protein-energy malnutrition early in life.

D. Hill, I. Swenne, R. Milner, 1991, Upsala journal of medical sciences.

IGF-binding protein mRNAs in the human fetus: tissue and cellular distribution of developmental expression.

V. Han, D. Hill, P. Delhanty, 1996, Hormone research.

Cellular distribution and ontogeny of insulin-like growth factors (IGFs) and IGF binding protein messenger RNAs and peptides in developing rat pancreas.

J. Petrik, V. Han, D. Hill, 1999, The Journal of endocrinology.

Regulation of DNA synthesis in human fetal hepatocytes by placental lactogen, growth hormone, and insulin‐like growth factor I/somatomedin‐C

D. Hill, I. Swenne, R. Milner, 1987, Journal of cellular physiology.

Interaction between endocrine and paracrine peptides in prenatal growth control

D. Hill, R. Milner, R. Milner, 1987, European Journal of Pediatrics.

Increased thymidine incorporation into fetal rat cartilage in vitro in the presence of human somatomedin, epidermal growth factor and other growth factors.

M. Preece, D. Hill, R. Milner, 1983, The Journal of endocrinology.

Ontogeny of regeneration of beta-cells in the neonatal rat after treatment with streptozotocin.

D. Hill, E. Arany, S. Thyssen, 2006, Endocrinology.

Taurine supplement in early life altered islet morphology, decreased insulitis and delayed the onset of diabetes in non-obese diabetic mice

B. Reusens, C. Remacle, B. Strutt, 2004, Diabetologia.

A low protein diet alters the balance of islet cell replication and apoptosis in the fetal and neonatal rat and is associated with a reduced pancreatic expression of insulin-like growth factor-II.

B. Reusens, C. Remacle, J. Petrik, 1999, Endocrinology.

Growth factor control of pancreatic B cell hyperplasia.

D. Hill, J. Hogg, 1991, Bailliere's clinical endocrinology and metabolism.

Growth Hormone Regulation of Somatomedin C/Insulin-Like Growth Factor I Production and DNA Replication in Fetal Rat Islets in Tissue Culture

D. Hill, I. Swenne, R. Milner, 1987, Diabetes.

Taurine supplementation to a low protein diet during foetal and early postnatal life restores a normal proliferation and apoptosis of rat pancreatic islets

B. Reusens, C. Remacle, D. Hill, 2002, Diabetologia.

Intermittent umbilical cord occlusion in the ovine fetus: effects on blood glucose, insulin, and glucagon and on pancreatic development.

D. Hill, T. McDonald, B. Richardson, 2001, Journal of the Society for Gynecologic Investigation.

NOX2 Deficiency Protects Against Streptozotocin-Induced β-Cell Destruction and Development of Diabetes in Mice

B. Strutt, D. Hill, Xiangru Lu, 2010, Diabetes.

Increased somatomedin and cartilage metabolic activity in rabbit fetuses injected with insulin in utero

D. Hill, R. Milner, 1980, Diabetologia.

Reduced Plasma Somatomedin Activity and Costal Cartilage Sulfate Incorporation Activity during Experimental Growth Retardation in the Fetal Rat

N. Fieller, D. Hill, F. D. De Prins, 1984, Pediatric Research.

Somatomedins and fetal growth.

D. Hill, R. Milner, 1981, Ciba Foundation symposium.

Prolactin-stimulated production of somatomedin by rat liver

D. Hill, M. Francis, M. J. Francis, 1975, Nature.

Fibroblast growth factor-2 and fibroblast growth factor receptor-1 mRNA expression and peptide localization in placentae from normal and diabetic pregnancies.

D. Hill, E. Arany, David J. Hill, 1998, Placenta.

Distribution of insulin-like growth factor peptides in the developing chick embryo.

D. Hill, J. Ralphs, L. Wylie, 1990, Development.

Placental lactogen and growth hormone receptors in human fetal tissues: relationship to fetal plasma human placental lactogen concentrations and fetal growth.

S. Handwerger, D. Hill, M. Freemark, 1988, The Journal of clinical endocrinology and metabolism.

The effect of intermittent umbilical cord occlusion on insulin-like growth factors and their binding proteins in preterm and near-term ovine fetuses.

V. Han, D. Hill, B. Richardson, 2000, The Journal of endocrinology.

Adipose tissue gene expression profiling reveals distinct molecular pathways that define visceral adiposity in offspring of maternal protein-restricted rats.

A. Chamson-Reig, D. Hill, E. Arany, 2005, American journal of physiology. Endocrinology and metabolism.

Insulin is a mitogen for isolated epiphyseal growth plate chondrocytes from the fetal lamb.

D. Hill, D. de Sousa, 1990, Endocrinology.

ß-Cell-specific pyruvate dehydrogenase deficiency impairs glucose-stimulated insulin secretion.

G. Cline, D. Hill, Pushpankur Ghoshal, 2010, American journal of physiology. Endocrinology and metabolism.

Effects of cortisol on cell proliferation and proteoglycan synthesis and degradation in cartilage zones of the calf costochondral growth plate in vitro with and without rat plasma somatomedin activity.

D. Hill, 1981, The Journal of endocrinology.

The Impact of Abnormal Glucose Tolerance and Obesity on Fetal Growth

D. Hill, M. K. Campbell, S. Evers, 2015, Journal of diabetes research.

Direct comparison of the abilities of bone marrow mesenchymal versus hematopoietic stem cells to reverse hyperglycemia in diabetic NOD.SCID mice

A. Chamson-Reig, B. Strutt, D. Hill, 2018, Islets.

Placental control of metabolic adaptations in the mother for an optimal pregnancy outcome. What goes wrong in gestational diabetes?

D. Hill, 2018, Placenta.

Featured Article: Beta cell specific pyruvate dehydrogenase alpha gene deletion results in a reduced islet number and β-cell mass postnatally

B. Strutt, D. Hill, M. Srinivasan, 2014, Experimental biology and medicine.

Changes in islet microvasculature following streptozotocin-induced β-cell loss and subsequent replacement in the neonatal rat

D. Hill, E. Arany, J. Nicholson, 2010, Experimental biology and medicine.

A low protein diet in early life delays the onset of diabetes in the non-obese diabetic mouse.

A. Chamson-Reig, D. Hill, E. Arany, 2009, The Journal of endocrinology.

Intermittent Umbilical Cord Occlusion in the Ovine Fetus: Effects on Blood Glucose, Insulin, and Glucagon and on Pancreatic Development

D. Hill, T. McDonald, B. Richardson, 2001, The Journal of the Society for Gynecologic Investigation: JSGI.

A Long-Term High-Carbohydrate Diet Causes an Altered Ontogeny of Pancreatic Islets of Langerhans in the Neonatal Rat

J. Petrik, D. Hill, M. Patel, 2001, Pediatric Research.

Increased and persistent circulating insulin-like growth factor II in neonatal transgenic mice suppresses developmental apoptosis in the pancreatic islets.

B. Strutt, D. Hill, S. Zaina, 2000, Endocrinology.

Ontogeny of Fibroblast Growth Factors in the Early Development of the Rat Endocrine Pancreas

D. Hill, E. Arany, 2000, Pediatric Research.

The ontogeny of insulin-like growth factor (IGF) and IGF-binding protein gene expression in the rat pancreas.

V. Han, D. Hill, J. Hogg, 1994, Journal of molecular endocrinology.

IGF-I has a dual effect on insulin release from isolated, perifused adult rat islets of Langerhans.

D. Hill, T. McDonald, R. Sedran, 1997, The Journal of endocrinology.

Developmental regulation of insulin-like growth factor II mRNA in different rat tissues.

Alastair, M. Rechler, D. Hill, 1986, The Journal of biological chemistry.

Interactions of nutrients, insulin-like growth factors (IGFs) and IGF-binding proteins in the regulation of DNA synthesis by isolated fetal rat islets of Langerhans.

D. Clemmons, V. Han, D. Hill, 1993, The Journal of endocrinology.

Somatomedin-C in Human Fetal Pancreas: Cellular Localization and Release During Organ Culture

D. Hill, I. Swenne, R. Milner, 1987, Diabetes.

Identification of Somatomedin/Insulin-Like Growth Factor Immunoreactive Cells in the Human Fetus

V. Han, D. Hill, J. Lauder, 1987, Pediatric Research.

Decrease in Ins+Glut2LO β-cells with advancing age in mouse and human pancreas.

M. Hara, S. Chakrabarti, B. Strutt, 2017, The Journal of endocrinology.

Control of cellular multiplication and differentiation

V. Han, D. Hill, 1989 .

METABOLIC ADAPTATIONS TO PREGNANCY IN HEALTHY AND GESTATIONAL DIABETIC PREGNANCIES: THE PANCREAS - PLACENTA AXIS.

D. Hill, Sandra K Szlapinski, Sandra K. Szlapinski, 2020, Current vascular pharmacology.

Increased islet cell proliferation, decreased apoptosis, and greater vascularization leading to beta-cell hyperplasia in mutant mice lacking insulin.

D. Hill, R. Joshi, D. Bucchini, 2002, Endocrinology.

The Renal Expression of Transforming Growth Factor-β Isoforms and Their Receptors in Acute and Chronic Experimental Diabetes in Rats.

J. Petrik, D. Hill, A. Logan, 2000, Endocrinology.

Increased levels of serum fibroblast growth factor-2 in diabetic pregnant women with retinopathy.

D. Hill, A. Flyvbjerg, E. Arany, 1997, The Journal of clinical endocrinology and metabolism.

Growth hormone regulation of DNA replication, but not insulin production, is partly mediated by somatomedin-C/insulin-like growth factor I in isolated pancreatic islets from adult rats

D. Hill, I. Swenne, 1989, Diabetologia.

Effects of platelet-derived growth factor and somatomedin-C/insulin-like growth factor I on the deoxyribonucleic acid replication of fetal rat islets of Langerhans in tissue culture.

C. Heldin, D. Hill, I. Swenne, 1988, Endocrinology.

Increased alpha and beta cell mass during mouse pregnancy is not dependent on transdifferentiation

B. Strutt, D. Hill, Sandra K Szlapinski, 2020, Experimental biology and medicine.

Identification and action of N-myc downstream regulated gene 4 A2 in rat pancreas.

D. Hill, J. Wang, 2009, The Journal of endocrinology.

Adjuvant Immunotherapy Increases β Cell Regenerative Factor Reg2 in the Pancreas of Diabetic Mice

R. Sherwin, M. Cameron, D. Kelvin, 2010, The Journal of Immunology.

An increase in immature β-cells lacking Glut2 precedes the expansion of β-cell mass in the pregnant mouse

B. Strutt, D. Hill, Christine A Beamish, 2017, PloS one.

Acetone Ingestion Mimics a Fasting State to Improve Glucose Tolerance in a Mouse Model of Gestational Hyperglycemia

B. Strutt, D. Hill, E. Arany, 2021, International journal of molecular sciences.

Ontology of the apelinergic system in mouse pancreas during pregnancy and relationship with β-cell mass

B. Strutt, D. Hill, Sandra K Szlapinski, 2021, Scientific Reports.

Altered pancreas remodeling following glucose intolerance in pregnancy in mouse.

Renee T King, B. Strutt, D. Hill, 2020, The Journal of endocrinology.

maternal mild food restriction reverses this phenotype hyperinsulinemia, and adult-onset obesity and Maternal hyperinsulinemia predisposes rat fetuses for

B. Strutt, D. Hill, R. Aalinkeel, 2006 .

Maternal hyperinsulinemia predisposes rat fetuses for hyperinsulinemia, and adult-onset obesity and maternal mild food restriction reverses this phenotype.

B. Strutt, D. Hill, R. Aalinkeel, 2006, American journal of physiology. Endocrinology and metabolism.

Pleiotrophin Expression and Actions in Pancreatic β-Cells

B. Strutt, D. Hill, Sandra K Szlapinski, 2022, Frontiers in Endocrinology.

Presence and possible role of vascular endothelial growth factor in thyroid cell growth and function.

D. Hill, G. Fong, C. Schramek, 1998, The Journal of endocrinology.

Insulin-like growth factor binding protein-4, -5 and -6 mRNAs in the human fetus: localization to sites of growth and differentiation?

V. Han, D. Hill, P. Delhanty, 1993, Growth regulation.

Mitogenic action of gastrin-releasing polypeptide on isolated epiphyseal growth plate chondrocytes from the ovine fetus.

D. Hill, T. McDonald, 1992, Endocrinology.

Bovine oviductal and embryonic insulin-like growth factor binding proteins: possible regulators of "embryotrophic" insulin-like growth factor circuits.

P. De Los Rios, V. Han, D. Hill, 1997, Biology of reproduction.

Altered expression of insulin-like growth factor-I (IGF-I) and IGF binding proteins during rat thyroid hyperplasia and involution.

D. Hill, A. Logan, I. Phillips, 1994, Growth factors.

Changes in sensitivity of hepatocytes isolated from regenerating rat liver to the growth inhibitory action of transforming growth factor beta.

D. Hill, A. Strain, Alastair J. Strain, 2008, Liver.

Coordinated pattern of expression and localization of insulin-like growth factor-II (IGF-II) and IGF-binding protein-2 in the adult rat brain.

D. Hill, M. Berry, A. Logan, 1994, Endocrinology.

Dietary protein and insulin-like growth factor-I content following unilateral nephrectomy.

D. Hill, A. E. El Nahas, J. E. Le Carpentier, 1989, Kidney international. Supplement.

The involvement of interleukin-22 in the expression of pancreatic beta cell regenerative Reg genes

D. Hill, L. Fouser, Bhagirath Singh, 2013, Cell Regeneration.

Rapid clearance of human insulin-like growth factor binding protein-3 from the rat circulation and cellular localization in liver, kidney and stomach.

P. Zabel, D. Hill, E. Arany, 1996, Growth regulation.

Rapid clearance of insulin-like growth factor (IGF)-binding protein species from blood and an associated fall in circulating IGF-I following partial hepatectomy in the rat.

V. Han, D. Hill, E. Arany, 1993, The Journal of endocrinology.

Effects of atorvastatin on the regeneration of pancreatic {beta}-cells after streptozotocin treatment in the neonatal rodent.

D. Hill, E. Arany, K. Marchand, 2010, American journal of physiology. Endocrinology and metabolism.

Adjuvant Immunotherapy Increases b Cell Regenerative Factor Regeneration Gene 2 in the Pancreas of Diabetic Mice

R. Sherwin, M. Cameron, D. Kelvin, 2010 .

Perspectives in Diabetes Neonatal-Cell Apoptosis A Trigger for Autoimmune Diabetes ?

D. Finegood, D. Hill, E. Arany, 1999 .

Expression and Release of Basic Fibroblast Growth Factor by Epiphyseal Growth Plate Chondrocytes

D. Hill, A. Logan, A. González, 1991, Annals of the New York Academy of Sciences.

Stimulation of DNA and Protein Synthesis in Epiphyseal Growth Plate Chondrocytes by Fibroblast Growth Factors

D. Hill, A. Logan, D. Sousa, 1991, Annals of the New York Academy of Sciences.

Paracrinology of growth regulation.

V. Han, D. Hill, 1991, Journal of developmental physiology.

Fibroblast growth factor-2 (FGF-2) is present in maternal and cord serum, and in the mother is associated with a binding protein immunologically related to the FGF receptor-1.

D. Hill, G. Tevaarwerk, E. Arany, 1995, The Journal of clinical endocrinology and metabolism.

Monoclonal antibodies can enhance the biological activity of thyrotropin.

D. Hill, R. Aston, J. Ivanyi, 1987, Endocrinology.

Expression of insulin-like growth factors (IGFs) and their binding proteins (IGF BPs) during pancreatic development in rat, and modulation of IGF actions on rat islet DNA synthesis by IGF BPs.

D. Hill, J. Hogg, 1992, Advances in experimental medicine and biology.

Relative abundance and molecular size of immunoreactive insulin-like growth factors I and II in human fetal tissues.

D. Hill, 1990, Early human development.

Fetal rat myoblasts release both rat somatomedin-C (SM-C)/insulin-like growth factor I (IGF I) and multiplication-stimulating activity in vitro: partial characterization and biological activity of myoblast-derived SM-C/IGF I.

D. Hill, S. Nissley, D. Morrell, 1985, Endocrinology.

Cultured fetal rat myoblasts release peptide growth factors which are immunologically and biologically similar to somatomedin

D. Hill, R. Milner, A. Holder, 1984, Journal of cellular physiology.

Insulin-like growth factor (IGF)-binding protein release by human fetal fibroblasts: dependency on cell density and IGF peptides.

D. Clemmons, D. Hill, C. Camacho-Hubner, 1989, The Journal of endocrinology.

Effects of human placental lactogen and growth hormone on the production of insulin and somatomedin C/insulin-like growth factor I by human fetal pancreas in tissue culture.

D. Hill, I. Swenne, R. Milner, 1987, The Journal of endocrinology.

Regulation of amino acid uptake and deoxyribonucleic acid synthesis in isolated human fetal fibroblasts and myoblasts: effect of human placental lactogen, somatomedin-C, multiplication-stimulating activity, and insulin.

D. Hill, R. Milner, A. Strain, 1986, The Journal of clinical endocrinology and metabolism.

Incorporation of [3H]thymidine by isolated fetal myoblasts and fibroblasts in response to human placental lactogen (HPL): Possible mediation of HPL action by release of immunoreactive SM‐C

D. Hill, R. Milner, C. Crace, 1985, Journal of cellular physiology.

Gastrin-releasing peptide is produced in the pregnant ovine uterus.

D. Hill, E. Spindel, T. McDonald, 1994, Endocrinology.

Expression of the proto-oncogenes C-H-ras and N-ras in early second trimester human fetal tissues.

D. Hill, A. Strain, H. Mellersh, 1986, Biochemical and biophysical research communications.

Bi‐functional action of transforming growth factor‐β on DNA synthesis in early passage human fetal fibroblasts

D. Hill, I. Swenne, S. Elstow, 1986, Journal of cellular physiology.

Immunohistochemical localization of insulin-like growth factors (IGFs) and IGF binding proteins -1, -2 and -3 in human placenta and fetal membranes.

D. Clemmons, D. Hill, J. Challis, 1993, Placenta.

Tissue and Plasma Somatomedin-C/Insulin-Like Growth Factor I Concentrations in the Human Fetus during the First Half of Gestation

D. Hill, A. D'ercole, A. Strain, 1986, Pediatric Research.

Degradation of IGF-binding protein-3 by proteases in cultured FRTL-5 rat thyroid cells.

D. Hill, J. Wang, G. P. Becks, 1997, The Journal of endocrinology.

Presence of transforming growth factor-beta-like activity in multiple fetal rat tissues.

D. Hill, R. Milner, A. Strain, 1986, Cell biology international reports.

Apoptosis during goitre involution - the role of Bcl-2.

D. Hill, A. Logan, M. Sheppard, 2000, The Journal of endocrinology.

Regulation of thyroid hormone synthesis in cultured ovine thyroid follicles.

D. Hill, I. Phillips, J. Wang, 1992, Endocrinology.

Effect of maternal hyperalimentation on intrauterine growth retardation.

D. Hill, F. D. De Prins, R. Milner, 1988, Archives of disease in childhood.

Cell Multiplication and Differentiation

D. Hill, D. Hill, 1989, Acta paediatrica Scandinavica. Supplement.

Purification and characterization of a unique high molecular weight form of insulin-like growth factor II.

D. Hill, R. Schlueter, B. Hampton, 1987, Endocrinology.

Lack of growth hormone-dependent somatomedins or growth retardation in hypophysectomized fetal lambs.

D. Hill, M. Parkes, 1985, The Journal of endocrinology.

Raised plasma somatomedin activity and cartilage metabolic activity (35S sulphate uptake in vitro) in the fetus of the mildly diabetic pregnant rat

D. Hill, R. Milner, R. A. Sheffrin, 1982, Diabetologia.

Elimination of radiolabelled recombinant human insulin-like growth factor binding protein-3 from the circulation, and its distribution amongst organs and tissues in adult male rats

P. Zabel, D. Hill, D. Freeman, 1993, Regulatory Peptides.

Role of Delayed Neuroglial Activation in Impaired Cerebral Blood Flow Restoration Following Comorbid Injury

D. Hill, E. Arany, Z. Amtul, 2019, Cellular and Molecular Neurobiology.

Control of protein and matrix-molecule synthesis in isolated ovine fetal growth-plate chondrocytes by the interactions of basic fibroblast growth factor, insulin-like growth factors-I and -II, insulin and transforming growth factor-beta 1.

D. Hill, A. Logan, M. Mcgarry, 1992, The Journal of endocrinology.

Distinct Sites of Insulin-like Growth Factor (igf)-ii Expression and Localization in Lesioned Rat Brain: Possible Roles of Igf Binding Proteins (igfbps) in the Mediation of Igf-ii Activity*

D. Hill, M. Berry, A. Logan, 2022 .

Growth factors in embryogenesis.

D. Hill, R. Milner, A. Strain, 1987, Oxford reviews of reproductive biology.

Fetal programming of the pancreatic β cells and the implications for postnatal diabetes

D. Hill, 1999 .

Growth factors and cytokines in the fetus and placenta

V. Han, D. Hill, 1997 .

Growth factors and the regulation of pre- and postnatal growth.

D. Hill, J. Hogg, 1989, Bailliere's clinical endocrinology and metabolism.

From the Bench to the Bedside

D. Hill, D. J. Hill, David J. Hill, 2017 .

Modulation of microsomal glucose‐6‐phosphate translocase activity by free fatty acids: Implications for lipid domain structure in microsomal membranes

M. Karnovsky, D. Hill, E. Dawidowicz, 1983, Journal of cellular physiology.

Peptide growth factors and their interactions during chondrogenesis.

D. Hill, A. Logan, D. J. Hill, 1992, Progress in growth factor research.

Neuropeptide Y is produced in visceral adipose tissue and promotes proliferation of adipocyte precursor cells via the Y1 receptor

D. Hill, E. Arany, H. Guan, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Pancreatic Development and Adult Diabetes

D. Hill, B. Duvillié, David J Hill, 2000, Pediatric Research.

Mitochondrial Calpain-1 Disrupts ATP Synthase and Induces Superoxide Generation in Type 1 Diabetic Hearts: A Novel Mechanism Contributing to Diabetic Cardiomyopathy

S. Xiong, P. Greer, T. Peng, 2015, Diabetes.

Pancreatic islet cell survival following islet isolation: the role of cellular interactions in the pancreas.

D. Agapitos, L. Rosenberg, D. Hill, 1999, The Journal of endocrinology.

Neonatal beta-cell apoptosis: a trigger for autoimmune diabetes?

D. Finegood, D. Hill, E. Arany, 2000, Diabetes.

Tumour suppression associated with expression of human insulin-like growth factor II.

P. Schofield, D. Hill, A. Lee, 1991, British Journal of Cancer.

Tumoursuppression associated withexpression ofhumaninsulin-like growth factor II

P. Schofield, D. Hill, A. Lee, 1991 .

Hormonal regulation of insulin-like growth factor (IGF)-binding proteins secreted by isolated sheep thyroid epithelial cells: relationship with iodine organification.

D. Hill, E. Hanada, I. Phillips, 1991, The Journal of endocrinology.

Hormonal regulation and biological actions of insulin-like growth factor binding proteins in isolated ovine thyroid follicles.

V. Han, D. Hill, I. Phillips, 1994, Endocrinology.

Distribution of Fibroblast Growth Factor (FGF)-2 and FGF Receptor-1 Messenger RNA Expression and Protein Presence in the Mid-Trimester Human Fetus

P. Maher, D. Hill, A. Logan, 1996, Pediatric Research.

Fibroblast growth factor 2 is elevated in term maternal and cord serum and amniotic fluid in pregnancies complicated by diabetes: relationship to fetal and placental size.

D. Hill, G. Tevaarwerk, E. Arany, 1995, The Journal of clinical endocrinology and metabolism.

Locations and molecular forms of gastrin-releasing peptide-like immunoreactive entities in ovine pregnancy

D. Hill, T. McDonald, S. St.-Pierre, 1996, Peptides.

Prolonged hypoxia induced by the reduction of maternal uterine blood flow alters insulin-like growth factor-binding protein-1 (IGFBP-1) and IGFBP-2 gene expression in the ovine fetus.

S. Hooper, V. Han, D. Hill, 1992, Endocrinology.

Insulin as a Growth Factor

D. Hill, R. Milner, D J Hill, 1985, Pediatric Research.

Peptide growth factor interactions in embryonic and fetal growth.

D. Hill, 1992, Hormone research.

Differential temporal and spatial post‐injury alterations in cerebral cell morphology and viability

D. Hill, E. Arany, Z. Amtul, 2020, The Journal of comparative neurology.

Spatial Dynamics of Vascular and Biochemical Injury in Rat Hippocampus Following Striatal Injury and Aβ Toxicity

D. Hill, E. Arany, Z. Amtul, 2018, Molecular Neurobiology.

The Effects of Low Protein During Gestation on Mouse Pancreatic Development and Beta Cell Regeneration

D. Hill, E. Arany, A. Cox, 2010, Pediatric Research.

Action of rat prolactin on plasma somatomedin levels in the rat and on somatomedin release from perfused rat liver.

D. Hill, M. Francis, R D Milner, 1977, The Journal of endocrinology.

Bioavailability: is this a key event in regulating the actions of peptide growth factors?

D. Hill, A. Logan, 1992, The Journal of endocrinology.

Targeted Inhibition of Calpain Reduces Myocardial Hypertrophy and Fibrosis in Mouse Models of Type 1 Diabetes

Y. Li, P. Greer, T. Peng, 2011, Diabetes.

Disruption of the dopamine d2 receptor impairs insulin secretion and causes glucose intolerance.

M. Rubinstein, A. Chamson-Reig, M. Wheeler, 2010, Endocrinology.

Altered Insulin/Insulin-Like Growth Factor Signaling in a Comorbid Rat model of Ischemia and β-Amyloid Toxicity

D. Hill, D. Cechetto, E. Arany, 2018, Scientific Reports.

Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II)

D. Hill, C. Graham, A. Ward, 1995, British Journal of Cancer.

Enhanced expression of transforming growth factor-beta 1 during thyroid hyperplasia in rats.

D. Hill, A. Logan, I. Phillips, 1994, The Journal of endocrinology.

Transforming growth factor β inhibits DNA synthesis in hepatocytes isolated from normal and regenerating rat liver

D. Hill, R. Milner, A. Strain, 1987 .

Transforming growth factor beta inhibits DNA synthesis in hepatocytes isolated from normal and regenerating rat liver.

D. Hill, R. Milner, A. Strain, 1987, Biochemical and biophysical research communications.

Relationship of morphology and follicular fluid environment of bovine oocytes to their developmental potential in vitro.

D. Hill, J. Walton, R. Stubbing, 1995, Theriogenology.

Insulin-like growth factors prevent cytokine-mediated cell death in isolated islets of Langerhans from pre-diabetic non-obese diabetic mice.

J. Petrik, D. Hill, T. McDonald, 1999, The Journal of endocrinology.

Increase of basic fibroblast growth factor (FGF) and FGF receptor messenger RNA during rat thyroid hyperplasia: temporal changes and cellular distribution.

D. Hill, A. Logan, I. Phillips, 1994, The Journal of endocrinology.

Stimulation of cartilage zones of the calf costochondral growth plate in vitro by growth hormone dependent rat plasma somatomedin activity.

D. Hill, 1979, The Journal of endocrinology.

Effects of a Comprehensive, Intensive Lifestyle Intervention Combined with Metformin Extended Release in Obese Adolescents

D. Hill, H. Prapavessis, J. Shoemaker, 2014, International scholarly research notices.

Metformin in combination with structured lifestyle intervention improved body mass index in obese adolescents, but did not improve insulin resistance

D. Hill, C. Clarson, F. Mahmud, 2009, Endocrine.

Pancreatic GABA and Serotonin Actions in the Pancreas and Fetal Programming of Metabolism

D. Hill, 2017 .

The effects of low protein during gestation on mouse pancreatic development and beta cell regeneration.

D. Hill, E. Arany, A. Cox, 2010, Pediatric research.

Relationship between Birth Weight and Metabolic Status in Obese Adolescents

D. Hill, H. Prapavessis, J. Shoemaker, 2013, ISRN obesity.

Selective deletion of endothelial cell calpain in mice reduces diabetic cardiomyopathy by improving angiogenesis

S. Xiong, P. Greer, T. Peng, 2019, Diabetologia.

Perinuclear localization of an intracellular binding protein related to the fibroblast growth factor (FGF) receptor 1 is temporally associated with the nuclear trafficking of FGF-2 in proliferating epiphyseal growth plate chondrocytes.

D. Hill, D. Kilkenny, D M Kilkenny, 1996, Endocrinology.

A Soluble Fibroblast Growth Factor Receptor is Released from HL-60 Promyelocytic Leukemia Cells: Implications for Paracrine Growth Control

D. Hill, G. Fong, J. Wang, 2000, Growth factors.

Characterization of insulin-like growth factor-binding proteins secreted by isolated sheep thyroid epithelial cells.

D. Hill, J. Wang, G. P. Becks, 1990, The Journal of endocrinology.

Interactive effects of nutrients and hormones on the expression of insulin‐like growth factor binding protein‐1 (IGFBP‐1) mRNA and peptide, and IGF I release from isolated adult rat hepatocytes

D. Hill, E. Arany, I. Phillips, 1993, Journal of cellular physiology.

Fetal growth signals.

D. Hill, R. Milner, 1989, Archives of disease in childhood.

Insulin-positive, Glut2-low cells present within mouse pancreas exhibit lineage plasticity and are enriched within extra-islet endocrine cell clusters

B. Strutt, D. Hill, E. Arany, 2016, Islets.

Cell cycle-dependent localization of immunoreactive basic fibroblast growth factor to cytoplasm and nucleus of isolated ovine fetal growth plate chondrocytes.

D. Hill, A. Logan, 1992, Growth factors.

A Low Protein Diet Alters the Balance of Islet Cell Replication and Apoptosis in the Fetal and Neonatal Rat and Is Associated with a Reduced Pancreatic Expression of Insulin-Like Growth Factor-II1.

B. Reusens, C. Remacle, J. Petrik, 1999, Endocrinology.

Divergent action of transforming growth factor beta on DNA synthesis in human foetal liver cells.

D. Hill, R. Milner, A. Strain, 1986, Cell biology international reports.

What is the role of growth hormone and related peptides in implantation and the development of the embryo and fetus.

D. Hill, 1992, Hormone research.

Retention of plasma somatomedin activity in the foetal rabbit following decapitation in utero.

D. Hill, R. Milner, P. Davidson, 1979, The Journal of endocrinology.

Glucocorticoid receptor expression is altered in pancreatic beta cells of the non-obese diabetic mouse during postnatal development.

D. Hill, E. Arany, A. Thompson, 2002, Metabolism: clinical and experimental.

Localization of calmodulin in differentiating pulmonary type II epithelial cells.

D. Hill, M. Karnovsky, T. Wright, 1984, Laboratory investigation; a journal of technical methods and pathology.

Cartilage response to plasma and plasma somatomedin activity in rats related to growth before and after birth.

D. Hill, R. Milner, S. J. Andrews, 1981, The Journal of endocrinology.

The renal expression of transforming growth factor-beta isoforms and their receptors in acute and chronic experimental diabetes in rats.

J. Petrik, D. Hill, A. Logan, 2000, Endocrinology.

Somatomedin C/insulin-like growth factor I: simplified purification procedure and biological activities of the purified growth factor.

M. Preece, D. Hill, K. Ray, 1986, The Journal of endocrinology.

The involvement of interleukin-22 in the expression of pancreatic beta cell regenerative Reg genes

D. Hill, L. Fouser, Bhagirath Singh, 2013, Cell Regeneration.

Rapid changes in somatomedin activity during insulin-induced hypoglycemia: possible release of an inhibitory factor.

D. Hill, J. Potter, R. Milner, 1981, The Journal of clinical endocrinology and metabolism.

Protein Restriction during Early Life in Rats Alters Pancreatic GABAA Receptor Subunit Expression and Glucagon Secretion in Adulthood

D. Hardy, D. Hill, V. Lux-Lantos, 2012 .

The spatial cerebral damage caused by larger infarct and β‐amyloid toxicity is driven by the anatomical/functional connectivity

D. Hill, E. Arany, Z. Amtul, 2019, The Journal of comparative neurology.

Changes in the immunohistochemical localisation of fibroblast growth factor-2, transforming growth factor-beta 1 and thrombospondin-1 are associated with early angiogenic events in the hyperplastic rat thyroid.

D. Hill, A. Logan, M. Sheppard, 1996, The Journal of endocrinology.

Somatomedin activity in tracheal fluid from the newborn infant.

D. Hill, R. Milner, R. Watson, 1984, The Journal of clinical endocrinology and metabolism.

The interrelationship between the development of bovine oocytes in vitro and their follicular fluid environment

D. Hill, J. Walton, R. Stubbings, 1993 .

Spatial Dynamics of Vascular and Biochemical Injury in Rat Hippocampus Following Striatal Injury and Aβ Toxicity

D. Hill, E. Arany, Z. Amtul, 2018, Molecular Neurobiology.

Scholarship@Western Scholarship@Western

B. Strutt, D. Hill, Jamie Bennett, 2022 .

A low protein diet in early life delays the onset of diabetes in the non-obese diabetic mouse.

A. Chamson-Reig, D. Hill, E. Arany, 2009, The Journal of endocrinology.

Role of Delayed Neuroglial Activation in Impaired Cerebral Blood Flow Restoration Following Comorbid Injury

D. Hill, E. Arany, Z. Amtul, 2019, Cellular and Molecular Neurobiology.

Distinct Sites of Insulin-like Growth Factor (igf)-ii Expression and Localization in Lesioned Rat Brain: Possible Roles of Igf Binding Proteins (igfbps) in the Mediation of Igf-ii Activity*

D. Hill, M. Berry, J. Holly, 2022 .

Decrease in Ins+Glut2LO β-cells with advancing age in mouse and human pancreas.

M. Hara, S. Chakrabarti, B. Strutt, 2017, The Journal of endocrinology.

Exposure of the Pregnant Rat to Low Protein Diet Causes Impaired Glucose Homeostasis in the Young Adult Offspring by Different Mechanisms in Males and Females

A. Chamson-Reig, D. Hill, E. Arany, 2009, Experimental biology and medicine.

Mitogenic actions of insulin on fetal and neonatal rat cells in vitro.

D. Hill, R. Milner, C. J. Crace, 1985, The Journal of endocrinology.

Lack of effect of chronic hyperinsulinaemia on growth and body composition in the fetal pig.

D. Hill, B. Colenbrander, A. Macdonald, 1983, Biology of the neonate.