S. Ribback

发表

Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations.

J. Zucman‐Rossi, D. Calvisi, Xin Chen, 2019, Cell metabolism.

Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinoma.

Frank Bergmann, Matthias Evert, Kai Breuhahn, 2013, Gastroenterology.

Cholangiocarcinomas can originate from hepatocytes in mice.

G. Gores, D. Calvisi, Xin Chen, 2012, The Journal of clinical investigation.

Focal pancreatic lesions in autoimmune pancreatitis and weight loss

R. Bülow, M. Lerch, S. Ribback, 2020, Gut.

Transcriptomic and Proteomic Analysis of Clear Cell Foci (CCF) in the Human Non-Cirrhotic Liver Identifies Several Differentially Expressed Genes and Proteins with Functions in Cancer Cell Biology and Glycogen Metabolism

D. Calvisi, T. Kietzmann, S. Ribback, 2020, Molecules.

D. Calvisi, T. Kietzmann, S. Ribback, 2020, bioRxiv.

Efficacy of MEK inhibition in a K-Ras-driven cholangiocarcinoma preclinical model

D. Calvisi, Xin Chen, A. Cossu, 2018, Cell Death & Disease.

Crenigacestat, a selective NOTCH1 inhibitor, reduces intrahepatic cholangiocarcinoma progression by blocking VEGFA/DLL4/MMP13 axis

D. Calvisi, G. Giannelli, Xin Chen, 2020, Cell Death & Differentiation.

Prognostic Impact of Membranous/Nuclear Epidermal Growth Factor Receptor Localization in Clear Cell Renal Cell Carcinoma

S. Ribback, A. Angius, G. Sotgiu, 2021, International journal of molecular sciences.

Tetraspanin 5 (TSPAN5), a Novel Gatekeeper of the Tumor Suppressor DLC1 and Myocardin-Related Transcription Factors (MRTFs), Controls HCC Growth and Senescence

T. Gudermann, S. Singer, R. Schneider-Stock, 2021, Cancers.

Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma

D. Calvisi, Xin Chen, S. Ribback, 2017, Cell cycle.

On the role of notch1 and adult hepatocytes in murine intrahepatic cholangiocarcinoma development

D. Calvisi, Xin Chen, S. Ribback, 2013, Hepatology.

Jagged 1 is a major Notch ligand along cholangiocarcinoma development in mice and humans

D. Calvisi, Xin Chen, A. Cossu, 2016, Oncogenesis.

Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development

D. Calvisi, Xin Chen, S. Dupont, 2020, Communications Biology.

The Hippo pathway effector TAZ induces intrahepatic cholangiocarcinoma in mice and is ubiquitously activated in the human disease

D. Calvisi, G. Giannelli, Xin Chen, 2022, Journal of Experimental & Clinical Cancer Research.

TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma.

Pavel Sumazin, D. Calvisi, Xin Chen, 2019, The American journal of pathology.

Pivotal Role of Fatty Acid Synthase in c-MYC Driven Hepatocarcinogenesis

D. Calvisi, Xin Chen, S. Zhong, 2020, International journal of molecular sciences.

Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice and humans.

D. Calvisi, Xin Chen, S. Ribback, 2016, Journal of hepatology.

A novel molecular signature identifies mixed subtypes in renal cell carcinoma with poor prognosis and independent response to immunotherapy

H. Moch, M. Gerlinger, A. Agaimy, 2022, Genome Medicine.

CD90 is regulated by notch1 and hallmarks a more aggressive intrahepatic cholangiocarcinoma phenotype

D. Calvisi, G. Giannelli, C. Simone, 2022, Journal of Experimental & Clinical Cancer Research.

A functional mTORC1 signaling is indispensable for c-Myc driven hepatocarcinogenesis

Ligong Chen, Xin Chen, A. Cossu, 2017 .

Both de novo synthetized and exogenous fatty acids support the growth of hepatocellular carcinoma cells

D. Calvisi, Xin Chen, S. Ribback, 2017, Liver international : official journal of the International Association for the Study of the Liver.

Estradiol receptors agonists induced effects in rat intestinal microcirculation during sepsis.

S. Ribback, F. Dombrowski, V. Černý, 2013, Microvascular research.

p53 is functionally inhibited in clear cell renal cell carcinoma (ccRCC): a mechanistic and correlative investigation into genetic and molecular characteristics

M. Burchardt, C. Lillig, S. Ribback, 2021, Journal of Cancer Research and Clinical Oncology.

Mobilization of CD11b+/Ly6chi monocytes causes multi organ dysfunction syndrome in acute pancreatitis

M. Mack, M. Lerch, O. Otto, 2022, Frontiers in Immunology.

Deregulated c-Myc requires a functional HSF1 for experimental and human hepatocarcinogenesis

D. Calvisi, Xin Chen, A. Cossu, 2017, Oncotarget.

Combined CDK4/6 and Pan-mTOR Inhibition Is Synergistic Against Intrahepatic Cholangiocarcinoma

D. Calvisi, Xin Chen, Hongbo Hu, 2018, Clinical Cancer Research.

ScoMorphoFISH: A deep learning enabled toolbox for single‐cell single‐mRNA quantification and correlative (ultra‐)morphometry

M. Pollheimer, J. Bräsen, S. Ribback, 2022, Journal of cellular and molecular medicine.

Robust Multiarray Average (RMA) implementation from the R-package oligo. Microarrays from C2, C4 and C5 were normalized individually using the SCAN method

H. Moch, M. Gerlinger, A. Agaimy, 2022 .

Inhibition of MELK Protooncogene as an Innovative Treatment for Intrahepatic Cholangiocarcinoma

D. Calvisi, A. Cossu, S. Ribback, 2019, Medicina.

Obstruction of Capillaries by circulating large Monocytes causes Multi Organ Dysfunction Syndrome (MODS) in Acute Pancreatitis

M. Mack, M. Lerch, O. Otto, 2021 .

Voriconazole as mono-therapy in orbitofrontal erosive aspergillosis without gross total resection: A case report and review of literature

R. Ewert, S. Ribback, H. Schroeder, 2018, Clinical Neurology and Neurosurgery.

NADPH Oxidase Contributes to Resistance against Aggregatibacter actinomycetemcomitans-Induced Periodontitis in Mice

B. Holtfreter, T. Kocher, S. Ribback, 2016, Infection and Immunity.

Central role of mTORC1 downstream of YAP/TAZ in hepatoblastoma development

D. Calvisi, Xin Chen, Pin Liu, 2017, Oncotarget.

Nodular hemangiomatosis of pleura and peritoneum.

A. Tannapfel, S. Ribback, F. Dombrowski, 2011, Pathology, research and practice.

Hippo Cascade Controls Lineage Commitment of Liver Tumors in Mice and Humans.

D. Calvisi, Xin Chen, W. Cong, 2018, The American journal of pathology.

HBPD Table of Contents, Vol. 16, No. 6, 2017

Q. Su, S. Ribback, D. Mayer, 2017, Digestive Surgery.

SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice

D. Calvisi, Xin Chen, S. Ribback, 2014, Oncotarget.

V‐AKT murine thymoma viral oncogene homolog/mammalian target of rapamycin activation induces a module of metabolic changes contributing to growth in insulin‐induced hepatocarcinogenesis

D. Calvisi, S. Ribback, M. Evert, 2012, Hepatology.

Focal Adhesion Kinase (FAK) promotes cholangiocarcinoma development and progression via YAP activation.

R. Schwabe, D. Calvisi, Xin Chen, 2021, Journal of hepatology.

A functional mammalian target of rapamycin complex 1 signaling is indispensable for c‐Myc‐driven hepatocarcinogenesis

D. Calvisi, Ligong Chen, Xin Chen, 2017, Hepatology.

Perioperative, Spatiotemporally Coordinated Activation of T and NK Cells Prevents Recurrence of Pancreatic Cancer.

M. Manns, S. Kubicka, D. Calvisi, 2018, Cancer research.

Histone H3K27 demethylase KDM6A is an epigenetic gatekeeper of mTORC1 signalling in cancer

Darjus F. Tschaharganeh, C. Plass, S. Lowe, 2021, Gut.

Comparison of liver oncogenic potential among human RAS isoforms

D. Calvisi, S. Ribback, F. Dombrowski, 2016, Oncotarget.

Tumour-specific delivery of siRNA-coupled superparamagnetic iron oxide nanoparticles, targeted against PLK1, stops progression of pancreatic cancer

N. Hosten, J. Mayerle, M. Lerch, 2016, Gut.

Differential requirement for de novo lipogenesis in cholangiocarcinoma and hepatocellular carcinoma of mice and humans

G. Gores, D. Calvisi, Xin Chen, 2016, Hepatology.

Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice

D. Calvisi, Xin Chen, S. Ribback, 2016, Scientific Reports.

HELLS Is Negatively Regulated by Wild-Type P53 in Liver Cancer by a Mechanism Involving P21 and FOXM1

B. Goeppert, S. Singer, C. Sticht, 2022, Cancers.

Loss of Fbxw7 synergizes with activated AKT signaling to promote c-Myc dependent cholangiocarcinogenesis.

D. Calvisi, Xin Chen, A. Cossu, 2019, Journal of hepatology.

Hepatic expression of Sonic Hedgehog induces liver fibrosis and promotes hepatocarcinogenesis in a transgenic mouse model.

D. Calvisi, J. Eun, S. Nam, 2016, Journal of hepatology.

Thioredoxin 1 (Trx1) is associated with poor prognosis in clear cell renal cell carcinoma (ccRCC): an example for the crucial role of redox signaling in ccRCC

T. Klatte, M. Burchardt, C. Lillig, 2021, World Journal of Urology.

PI3K/AKT/mTOR pathway plays a major pathogenetic role in glycogen accumulation and tumor development in renal distal tubules of rats and men

D. Calvisi, M. Burchardt, S. Ribback, 2015, Oncotarget.

Distinct and Overlapping Roles of Hippo Effectors YAP and TAZ During Human and Mouse Hepatocarcinogenesis

D. Calvisi, Xin Chen, S. Ribback, 2020, Cellular and molecular gastroenterology and hepatology.

Administration of Gemcitabine After Pancreatic Tumor Resection in Mice Induces an Antitumor Immune Response Mediated by Natural Killer Cells.

M. Manns, S. Kubicka, D. Calvisi, 2016, Gastroenterology.

Immune Cell and Stromal Signature Associated With Progression-Free Survival of Patients With Resected Pancreatic Ductal Adenocarcinoma.

J. D'haese, T. Kohlmann, J. Kleeff, 2018, Gastroenterology.

Effects of amitriptyline, fluoxetine, tranylcypromine and venlafaxine on rat vascular smooth muscle in vitro--the role of the endothelium.

H. Frieling, S. Bleich, S. Ribback, 2012, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

The mTORC2‐Akt1 Cascade Is Crucial for c‐Myc to Promote Hepatocarcinogenesis in Mice and Humans

D. Calvisi, Xin Chen, Meng Xu, 2019, Hepatology.

The Epidermal Growth Factor Receptor (EGFR) Inhibitor Gefitinib Reduces but Does Not Prevent Tumorigenesis in Chemical and Hormonal Induced Hepatocarcinogenesis Rat Models

D. Calvisi, S. Ribback, M. Evert, 2016, International journal of molecular sciences.

Activation of β-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice.

D. Calvisi, Xin Chen, L. Terracciano, 2014, Gastroenterology.

Crenigacestat, a selective NOTCH1 inhibitor, reduces intrahepatic cholangiocarcinoma progression by blocking VEGFA/DLL4/MMP13 axis

D. Calvisi, G. Giannelli, Xin Chen, 2020, Cell Death & Differentiation.

SNAI1 promotes the cholangiocellular phenotype, but not epithelial-mesenchymal transition, in a murine hepatocellular carcinoma model.

D. Calvisi, Xin Chen, Meng Xu, 2019, Cancer research.

Co-activation of PIK3CA and Yap promotes development of hepatocellular and cholangiocellular tumors in mouse and human liver

D. Calvisi, J. Calderaro, Xin Chen, 2015, Oncotarget.

Microvascular and lymphovascular tumour invasion are associated with poor prognosis and metastatic spread in renal cell carcinoma: a validation study in clinical practice

T. Klatte, S. Shariat, M. Burchardt, 2018, BJU international.

Evaluation of the prognostic role of co-morbidities on disease outcome in renal cell carcinoma patients

A. Belldegrun, A. Pantuck, T. Klatte, 2019, World Journal of Urology.

Hormonally Induced Hepatocellular Carcinoma in Diabetic Wild Type and Carbohydrate Responsive Element Binding Protein Knockout Mice

D. Calvisi, S. Singer, S. Ribback, 2021, Cells.

Efficacy of MEK inhibition in a K-Ras-driven cholangiocarcinoma preclinical model

D. Calvisi, Xin Chen, A. Cossu, 2018, Cell Death & Disease.

Structured illumination microscopy and automatized image processing as a rapid diagnostic tool for podocyte effacement

K. Amann, S. Ribback, F. Dombrowski, 2017, Scientific Reports.

Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans

D. Calvisi, Ligong Chen, Xin Chen, 2019, Gut.

The pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice

S. Ribback, M. Evert, F. Dombrowski, 2018 .

Overexpression of Mothers Against Decapentaplegic Homolog 7 Activates the Yes‐Associated Protein/NOTCH Cascade and Promotes Liver Carcinogenesis in Mice and Humans

D. Calvisi, Xin Chen, S. Ribback, 2021, Hepatology.

Toxoplasmosis after allogeneic stem cell transplantation—a single centre experience

C. Schmidt, S. Ribback, F. Dombrowski, 2012, Annals of Hematology.

The VENUSS prognostic model to predict disease recurrence following surgery for non-metastatic papillary renal cell carcinoma: development and evaluation using the ASSURE prospective clinical trial cohort

A. Pantuck, T. Klatte, S. Ribback, 2019, BMC Medicine.

Functional role of SGK3 in PI3K/Pten driven liver tumor development

D. Calvisi, Xin Chen, S. Ribback, 2019, BMC Cancer.

Loss of Pten synergizes with c-Met to promote hepatocellular carcinoma development via mTORC2 pathway

D. Calvisi, Xin Chen, Meng Xu, 2018, Experimental & Molecular Medicine.

Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice.

D. Calvisi, G. Giannelli, Xin Chen, 2017, Journal of hepatology.

Activated mutant forms of PIK3CA cooperate with RasV12 or c‐Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade

D. Calvisi, Xin Chen, J. Tao, 2016, Liver international : official journal of the International Association for the Study of the Liver.

β-Catenin sustains and is required for YES-associated protein oncogenic activity in cholangiocarcinoma.

R. Schwabe, D. Calvisi, Sungjin Ko, 2022, Gastroenterology.

Early Subcellular Hepatocellular Alterations in Mice Post Hydrodynamic Transfection: An Explorative Study

D. Calvisi, S. Ribback, M. Evert, 2023, Cancers.

Oncogene-dependent addiction to carbohydrate-responsive element binding protein in hepatocellular carcinoma

D. Calvisi, Xin Chen, S. Ribback, 2018, Cell cycle.

Molecular and metabolic changes in human liver clear cell foci resemble the alterations occurring in rat hepatocarcinogenesis.

D. Calvisi, S. Ribback, F. Dombrowski, 2013, Journal of hepatology.

LPA receptor 1 (LPAR1) is a novel interaction partner of Filamin A that promotes Filamin A phosphorylation, MRTF-A transcriptional activity and oncogene-induced senescence

R. Atreya, S. Singer, S. Ribback, 2022, Oncogenesis.

ScoMorphoFISH: A deep learning enabled toolbox for single‐cell single‐mRNA quantification and correlative (ultra‐)morphometry

J. Bräsen, S. Ribback, K. Endlich, 2021, bioRxiv.

TAZ is indispensable for c-MYC-induced hepatocarcinogenesis.

D. Calvisi, Xin Chen, Hong Wu, 2021, Journal of hepatology.

Structured illumination microscopy and automatized image processing as a rapid diagnostic tool for podocyte effacement

K. Amann, S. Ribback, F. Dombrowski, 2017, Scientific Reports.

Overexpression of Mothers Against Decapentaplegic Homolog 7 Activates the Yes‐Associated Protein/NOTCH Cascade and Promotes Liver Carcinogenesis in Mice and Humans

D. Calvisi, Xin Chen, S. Ribback, 2020, Hepatology.

Transgenic mouse model expressing P53R172H, luciferase, EGFP, and KRASG12D in a single open reading frame for live imaging of tumor

D. Calvisi, S. Ribback, F. Dombrowski, 2015, Scientific Reports.

The cytosolic isoform of glutaredoxin 2 promotes cell migration and invasion.

C. Lillig, J. Mostertz, M. Schwab, 2020, Biochimica et biophysica acta. General subjects.

Virtual slide telepathology with scanner systems for intraoperative frozen-section consultation.

Matthias Evert, Steffen Flessa, S. Ribback, 2014, Pathology, research and practice.

Inhibition of HSF1 suppresses the growth of hepatocarcinoma cell lines in vitro and AKT-driven hepatocarcinogenesis in mice.

D. Calvisi, Xin Chen, S. Ribback, 2017, Oncotarget.

Differential requirement for de novo lipogenesis in cholangiocarcinoma and hepatocellular carcinoma of mice and humans

G. Gores, D. Calvisi, Xin Chen, 2016, Hepatology.

Aberrant fucosylation sustains the NOTCH and EGFR/NF-κB pathways and has a prognostic value in human intrahepatic cholangiocarcinoma

D. Calvisi, G. Giannelli, Xin Chen, 2023, Hepatology.

YAP Accelerates NOTCH Driven Cholangiocarcinogenesis via mTORC1 in Mice.

D. Calvisi, Xin Chen, Hongwei Xu, 2021, The American journal of pathology.

Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocar- cinoma induced in mice by AKT and Yap co-expression

D. Calvisi, G. Giannelli, Xin Chen, 2017 .

On the role of notch1 and adult hepatocytes in murine intrahepatic cholangiocarcinoma development

D. Calvisi, Xin Chen, S. Ribback, 2013, Hepatology.

The Epidermal Growth Factor Receptor (EGFR) Inhibitor Gefitinib Reduces but Does Not Prevent Tumorigenesis in Chemical and Hormonal Induced Hepatocarcinogenesis Rat Models

D. Calvisi, S. Ribback, M. Evert, 2016, International journal of molecular sciences.

Perioperative, Spatiotemporally Coordinated Activation of T and NK Cells Prevents Recurrence of Pancreatic Cancer.

M. Manns, S. Kubicka, D. Calvisi, 2018, Cancer research.

Fatty Acid Synthase Promotes Hepatocellular Carcinoma Growth via S-Phase Kinase-Associated Protein 2/p27KIP1 Regulation

S. Ribback, G. Vidili, M. Dore, 2024, Medicina.

HSF1 is a prognostic determinant and therapeutic target in intrahepatic cholangiocarcinoma

G. Giannelli, S. Ribback, G. Vidili, 2024, Journal of experimental & clinical cancer research : CR.

SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice

D. Calvisi, Xin Chen, S. Ribback, 2014, Oncotarget.