Xiangru Lu

发表

Maternal diabetes up‐regulates NOX2 and enhances myocardial ischaemia/reperfusion injury in adult offspring

Lili Zhang, Xiaoyan Wang, Yan Wu, 2018, Journal of cellular and molecular medicine.

Neuronal Nitric Oxide Synthase Protects Against Myocardial Infarction–Induced Ventricular Arrhythmia and Mortality in Mice

Douglas L. Jones, S. M. Sims, S. Sims, 2009, Circulation.

Transfusion of fresh but not old stored blood reduces infarct size and improves cardiac function after acute myocardial infarction in anemic rats*

Xiangru Lu, Q. Feng, A. Xenocostas, 2012, Critical care medicine.

Fasudil , a Rho -

M. Halks-Miller, Xiangru Lu, Q. Feng, 2005 .

Fasudil, a Rho-Kinase Inhibitor, Attenuates Angiotensin II–Induced Abdominal Aortic Aneurysm in Apolipoprotein E–Deficient Mice by Inhibiting Apoptosis and Proteolysis

M. Halks-Miller, Xiangru Lu, Q. Feng, 2005, Circulation.

Myocardium-Specific Deletion of Rac1 Causes Ventricular Noncompaction and Outflow Tract Defects

Xiangru Lu, Q. Feng, Anish Engineer, 2021, Journal of cardiovascular development and disease.

JNK1/c-fos inhibits cardiomyocyte TNF-alpha expression via a negative crosstalk with ERK and p38 MAPK in endotoxaemia.

T. Peng, Xiangru Lu, Q. Feng, 2008, Cardiovascular research.

JNK 1 / c-fos inhibits cardiomyocyte TNF-a expression via a negative crosstalk with ERK and p 38 MAPK in endotoxaemia

T. Peng, Xiangru Lu, Q. Feng, 2009 .

In vivo TNF-alpha inhibition ameliorates cardiac mitochondrial dysfunction, oxidative stress, and apoptosis in experimental heart failure.

J. Marín-García, Xiangru Lu, Q. Feng, 2004, American journal of physiology. Heart and circulatory physiology.

Decreased responsiveness of vascular postjunctional α1‐, α2‐adrenoceptors and neuropeptide Y1 receptors in rats with heart failure

T. Hedner, Xiangru Lu, Q. Feng, 1999 .

Nitric Oxide Synthase-3 Promotes Embryonic Development of Atrioventricular Valves

Xiangru Lu, Q. Feng, F. Xiang, 2013, PloS one.

Role of heme oxygenase-1 in the cardioprotective effects of erythropoietin during myocardial ischemia and reperfusion.

Xiangru Lu, Q. Feng, Lamis Hammoud, 2009, American journal of physiology. Heart and circulatory physiology.

N-Acetylcysteine prevents congenital heart defects induced by pregestational diabetes

A. G. Gittenberger-de Groot, Xiangru Lu, Q. Feng, 2014, Cardiovascular Diabetology.

Cardiac-Specific Overexpression of Human Stem Cell Factor Promotes Epicardial Activation and Arteriogenesis After Myocardial Infarction

Douglas L. Jones, Xiangru Lu, Q. Feng, 2014, Circulation. Heart failure.

Rac1 Signaling Is Required for Anterior Second Heart Field Cellular Organization and Cardiac Outflow Tract Development

Xiangru Lu, Q. Feng, T. Drysdale, 2015, Journal of the American Heart Association.

Mortality After Myocardial Infarction in Mice

Douglas L. Jones, Xiangru Lu, Q. Feng, 2022 .

Endothelial nitric oxide synthase promotes neonatal cardiomyocyte proliferation by inhibiting tissue inhibitor of metalloproteinase-3 expression.

Xiangru Lu, Q. Feng, Lamis Hammoud, 2007, Cardiovascular research.

Role of tumor necrosis factor-α in myocardial dysfunction and apoptosis during hindlimb ischemia and reperfusion

Douglas L. Jones, Xiangru Lu, Q. Feng, 2006 .

Upregulation of corin gene expression in hypertrophic cardiomyocytes and failing myocardium.

Xiangru Lu, Q. Feng, M. Lei, 2004, American journal of physiology. Heart and circulatory physiology.

NOX2 Deficiency Protects Against Streptozotocin-Induced β-Cell Destruction and Development of Diabetes in Mice

B. Strutt, D. Hill, Xiangru Lu, 2010, Diabetes.

Pivotal Role of gp91phox-Containing NADH Oxidase in Lipopolysaccharide-Induced Tumor Necrosis Factor-α Expression and Myocardial Depression

T. Peng, Xiangru Lu, Q. Feng, 2005, Circulation.

Development of Heart Failure and Congenital Septal Defects in Mice Lacking Endothelial Nitric Oxide Synthase

T. Peng, Xiangru Lu, Q. Feng, 2002, Circulation.

Endothelial Nitric-oxide Synthase Enhances Lipopolysaccharide-stimulated Tumor Necrosis Factor-α Expression via cAMP-mediated p38 MAPK Pathway in Cardiomyocytes*

T. Peng, Xiangru Lu, Q. Feng, 2003, The Journal of Biological Chemistry.

North American ginseng inhibits myocardial NOX2-ERK1/2 signaling and tumor necrosis factor-α expression in endotoxemia.

Yan Wu, Xiangru Lu, Q. Feng, 2016, Pharmacological research.

Rac1 activation induces tumour necrosis factor-α expression and cardiac dysfunction in endotoxemia

Xiangru Lu, Q. Feng, F. Beier, 2010, Journal of cellular and molecular medicine.

Comparison of Initial Cell Retention and Clearance Kinetics After Subendocardial or Subepicardial Injections of Endothelial Progenitor Cells in a Canine Myocardial Infarction Model

F. Prato, Xiangru Lu, Q. Feng, 2010, Journal of Nuclear Medicine.

Effects of anemia and blood transfusion in acute myocardial infarction in rats

Xiangru Lu, Q. Feng, A. Xenocostas, 2010, Transfusion.

NADH oxidase signaling induces cyclooxygenase‐2 expression during lipopolysaccharide stimulation in cardiomyocytes

T. Peng, Xiangru Lu, Q. Feng, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Inhibition of intraflagellar transport protein-88 promotes epithelial-to-mesenchymal transition and reduces cardiac remodeling post-myocardial infarction.

Xiaoyan Wang, Xiangru Lu, Q. Feng, 2022, European journal of pharmacology.

Deficiency in endothelial nitric oxide synthase impairs myocardial angiogenesis.

Xiangru Lu, Q. Feng, Xue Zhao, 2002, American journal of physiology. Heart and circulatory physiology.

Erythropoietin is equally effective as fresh-blood transfusion at reducing infarct size in anemic rats

Xiangru Lu, Q. Feng, A. Xenocostas, 2010, Critical Care Medicine.

Maternal nicotine exposure induces congenital heart defects in the offspring of mice

Douglas L. Jones, Xiangru Lu, Q. Feng, 2020, Journal of cellular and molecular medicine.

S-Nitrosylation of STIM1 by neuronal nitric oxide synthase inhibits store-operated Ca2+ entry

S. Sims, P. Stathopulos, Xiangru Lu, 2018, bioRxiv.

North American ginseng protects the heart from ischemia and reperfusion injury via upregulation of endothelial nitric oxide synthase.

Yan Wu, Xiangru Lu, Q. Feng, 2011, Pharmacological research.

Endothelial Nitric Oxide Synthase Promotes Bone Marrow Stromal Cell Migration to the Ischemic Myocardium via Upregulation of Stromal Cell‐Derived Factor‐1α

Na Li, M. Karmazyn, Xiangru Lu, 2009, Stem cells.

Maternal Delta-9-Tetrahydrocannabinol Exposure Induces Abnormalities of the Developing Heart in Mice.

Xiangru Lu, Q. Feng, S. Laviolette, 2022, Cannabis and cannabinoid research.

Sapropterin reduces coronary artery malformation in offspring of pregestational diabetes mice.

K. Norozi, Xiangru Lu, Q. Feng, 2019, Nitric oxide : biology and chemistry.

Endogenous heme oxygenase induction is a critical mechanism attenuating apoptosis and restoring microvascular perfusion following limb ischemia/reperfusion.

Xiangru Lu, Q. Feng, R. Potter, 2004, Surgery.

Erythropoietin protects cardiomyocytes from apoptosis via up-regulation of endothelial nitric oxide synthase.

Xiangru Lu, Q. Feng, D. Burger, 2006, Cardiovascular research.

NOX2 Is Critical to Endocardial to Mesenchymal Transition and Heart Development

Yan Wu, Xiangru Lu, Q. Feng, 2020, Oxidative medicine and cellular longevity.

Sapropterin Treatment Prevents Congenital Heart Defects Induced by Pregestational Diabetes Mellitus in Mice

K. Norozi, Xiangru Lu, Q. Feng, 2018, Journal of the American Heart Association.

Sapropterin Treatment Prevents Congenital Heart Defects Induced by Pregestational Diabetes in Mice

K. Norozi, Xiangru Lu, Q. Feng, 2018, bioRxiv.

Pregestational Diabetes Induces Fetal Coronary Artery Malformation via Reactive Oxygen Species Signaling

Xiangru Lu, Q. Feng, Hoda Moazzen, 2014, Diabetes.

Inhibition of Na/K-ATPase promotes myocardial tumor necrosis factor-alpha protein expression and cardiac dysfunction via calcium/mTOR signaling in endotoxemia

S. M. Sims, S. Sims, Xiangru Lu, 2012, Basic Research in Cardiology.

Role of neuronal nitric oxide synthase in lipopolysaccharide-induced tumor necrosis factor-alpha expression in neonatal mouse cardiomyocytes.

S. M. Sims, S. Sims, T. Peng, 2007, Cardiovascular research.

Recombinant Human Annexin A5 Inhibits Proinflammatory Response and Improves Cardiac Function and Survival in Mice With Endotoxemia*

Xiangru Lu, Q. Feng, K. Brandl, 2014, Critical care medicine.

Deficiency in TIMP-3 increases cardiac rupture and mortality post-myocardial infarction via EGFR signaling: beneficial effects of cetuximab

Ming Lei, Lamis Hammoud, Xiangru Lu, 2011, Basic Research in Cardiology.

Tissue inhibitor of metalloproteinase-3 inhibits neonatal mouse cardiomyocyte proliferation via EGFR/JNK/SP-1 signaling.

Xiangru Lu, Q. Feng, Lamis Hammoud, 2009, American journal of physiology. Cell physiology.

Cardiomyocyte-Specific Overexpression of Human Stem Cell Factor Improves Cardiac Function and Survival After Myocardial Infarction in Mice

Xiangru Lu, P. Chidiac, Q. Feng, 2009, Circulation.

Role of tumor necrosis factor-alpha in myocardial dysfunction and apoptosis during hindlimb ischemia and reperfusion.

Douglas L. Jones, Xiangru Lu, Q. Feng, 2006, Critical care medicine.

Lack of endothelial nitric oxide synthase decreases cardiomyocyte proliferation and delays cardiac maturation.

Xiangru Lu, Q. Feng, D. Burger, 2006, American journal of physiology. Cell physiology.

Cardiomyocyte-specific overexpression of human stem cell factor protects against myocardial ischemia and reperfusion injury.

Xiangru Lu, Q. Feng, F. Xiang, 2013, International journal of cardiology.

Author ' s personal copy Cardiomyocyte-speci fi c overexpression of human stem cell factor protects against myocardial ischemia and reperfusion injury ☆

Xiangru Lu, Q. Feng, F. Xiang, 2013 .

Early and persistent activation of myocardial apoptosis, bax and caspases: insights into mechanisms of progression of heart failure.

Xiangru Lu, Q. Feng, G. Moe, 2002, Pathophysiology : the official journal of the International Society for Pathophysiology.

Inhibition of p38 MAPK decreases myocardial TNF-alpha expression and improves myocardial function and survival in endotoxemia.

T. Peng, Xiangru Lu, Q. Feng, 2003, Cardiovascular research.

Cardiomyocyte specific overexpression of a 37 amino acid domain of regulator of G protein signalling 2 inhibits cardiac hypertrophy and improves function in response to pressure overload in mice.

Xiangru Lu, P. Chidiac, Q. Feng, 2017, Journal of molecular and cellular cardiology.

Mitogen-activated protein kinase phosphatase-1 inhibits myocardial TNF-α expression and improves cardiac function during endotoxemia.

Yusen Liu, Xiangru Lu, Q. Feng, 2012, Cardiovascular research.

A charge-sensing region in the stromal interaction molecule 1 luminal domain confers stabilization-mediated inhibition of SOCE in response to S-nitrosylation

P. Stathopulos, Xiangru Lu, Q. Feng, 2018, The Journal of Biological Chemistry.

Nitric oxide synthase-3 deficiency results in hypoplastic coronary arteries and postnatal myocardial infarction.

A. G. Gittenberger-de Groot, Xiangru Lu, Q. Feng, 2014, European heart journal.

In vivo TNF-α inhibition ameliorates cardiac mitochondrial dysfunction, oxidative stress, and apoptosis in experimental heart failure

J. Marín-García, Xiangru Lu, Q. Feng, 2004 .

Novel circRNA-miRNA-mRNA networks regulated by maternal exercise in fetal hearts of pregestational diabetes.

Douglas L. Jones, Xiangru Lu, Q. Feng, 2022, Life sciences.

Annexin A5 Inhibits Endothelial Inflammation Induced by Lipopolysaccharide-Activated Platelets and Microvesicles via Phosphatidylserine Binding

Xiangru Lu, Q. Feng, D. Burger, 2023, Pharmaceuticals.

Longitudinal Follow-up of Cardiac Structure and Functional Changes in an Infarct Mouse Model Using Retrospectively Gated Micro-Computed Tomography

Maria Drangova, Nancy L Ford, Sarah A Detombe, 2008, Investigative radiology.

Inhibition of Rac1 reduces store overload‐induced calcium release and protects against ventricular arrhythmia

S. M. Sims, S. Sims, Lili Zhang, 2016, Journal of cellular and molecular medicine.

S-Nitrosylation of STIM1 by Neuronal Nitric Oxide Synthase Inhibits Store-Operated Ca2+ Entry.

S. Sims, P. Stathopulos, Xiangru Lu, 2018, Journal of molecular biology.

Maternal voluntary exercise mitigates oxidative stress and incidence of congenital heart defects in pre‐gestational diabetes

Douglas L. Jones, Xiangru Lu, Q. Feng, 2019, Journal of cellular and molecular medicine.

Tumor necrosis factor-α induces apoptosis via inducible nitric oxide synthase in neonatal mouse cardiomyocytes

Xiangru Lu, Q. Feng, Wei-zhong Song, 2000 .

Myocardial Infarction in Neonatal Mice, A Model of Cardiac Regeneration.

Xiangru Lu, Q. Feng, P. Arnold, 2016, Journal of visualized experiments : JoVE.

Elevation of an endogenous inhibitor of nitric oxide synthesis in experimental congestive heart failure.

T. Hedner, Xiangru Lu, Q. Feng, 1998, Cardiovascular research.

Rac1 Signaling Is Critical to Cardiomyocyte Polarity and Embryonic Heart Development

Xiangru Lu, Q. Feng, Carmen Leung, 2014, Journal of the American Heart Association.

Neuronal Nitric Oxide Synthase Protects Against Myocardial Infarction–Induced Ventricular Arrhythmia and Mortality in Mice

Douglas L. Jones, S. M. Sims, Xiangru Lu, 2009, Circulation.

Tissue inhibitor of metalloproteinase-3 inhibits neonatal mouse cardiomyocyte proliferation via EGFR/JNK/SP-1 signaling.

Xiangru Lu, Lamis Hammoud, D. Burger, 2009, American journal of physiology. Cell physiology.

Effects of anemia and blood transfusion in acute myocardial infarction in rats

Xiangru Lu, A. Xenocostas, I. Chin-Yee, 2010, Transfusion.

Pregestational Diabetes Induces Fetal Coronary Artery Malformation via Reactive Oxygen Species Signaling

Xiangru Lu, Hoda Moazzen, Murong Liu, 2014, Diabetes.

North American ginseng inhibits myocardial NOX2-ERK1/2 signaling and tumor necrosis factor-α expression in endotoxemia.

Yan Wu, Xiangru Lu, Chaoyi Qin, 2016, Pharmacological research.

Effects of L-arginine on endothelial and cardiac function in rats with heart failure.

Xiangru Lu, Q. Feng, J. Malcolm, 1999, European journal of pharmacology.

Maternal nicotine exposure induces congenital heart defects in the offspring of mice

Douglas L. Jones, Xiangru Lu, Anish Engineer, 2022, Journal of cellular and molecular medicine.

Pharmacokinetics of recombinant human annexin A5 (SY-005) in patients with severe COVID-19

Xiangru Lu, Aristide Laurel Mokale Kognou, Aleks Leligdowicz, 2024, Frontiers in Pharmacology.

Annexin A5 in Patients With Severe COVID-19 Disease: A Single-Center, Randomized, Double-Blind, Placebo-Controlled Feasibility Trial

F. Priestap, Xiangru Lu, M. Slessarev, 2023, Critical care explorations.

Attenuation of compensatory right ventricular hypertrophy and heart failure following monocrotaline-induced pulmonary vascular injury by the Na+-H+ exchange inhibitor cariporide.

M. Karmazyn, S. Chakrabarti, Xiangru Lu, 2001, The Journal of pharmacology and experimental therapeutics.

Cardiomyocyte specific overexpression of a 37 amino acid domain of regulator of G protein signalling 2 inhibits cardiac hypertrophy and improves function in response to pressure overload in mice.

Xiangru Lu, P. Chidiac, C. Nguyen, 2017, Journal of molecular and cellular cardiology.

Scholarship@Western Scholarship@Western

S. M. Sims, P. Stathopulos, Xiangru Lu, 2022 .

Lack of endothelial nitric oxide synthase decreases cardiomyocyte proliferation and delays cardiac maturation.

Xiangru Lu, D. Burger, Wei Song, 2006, American journal of physiology. Cell physiology.