Xuejun Jin

发表

Fraxinellone has anticancer activity in vivo by inhibiting programmed cell death‐ligand 1 expression by reducing hypoxia‐inducible factor‐1&agr; and STAT3

Juan Ma, Chunliu Mi, Yue‐Xiao Xing, 2018, Pharmacological research.

Imperatorin suppresses proliferation and angiogenesis of human colon cancer cell by targeting HIF-1α via the mTOR/p70S6K/4E-BP1 and MAPK pathways.

Juan Ma, Chunliu Mi, Zhe Wang, 2017, Journal of ethnopharmacology.

′ , 6-Dihydroxy-4-methoxyisoaurone Inhibits the HIF-1 a Pathway Through Inhibition of Akt / mTOR / p 70 S 6 K / 4 EBP 1 Phosphorylation

Juan Ma, Chunliu Mi, Xuejun Jin, 2014 .

4′,6-dihydroxy-4-methoxyisoaurone inhibits the HIF-1α pathway through inhibition of Akt/mTOR/p70S6K/4E-BP1 phosphorylation.

Juan Ma, Chunliu Mi, Xuejun Jin, 2014, Journal of pharmacological sciences.

Zinc finger protein 91 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation.

Juan Ma, Zhi Hong Zhang, Ming Yue Li, 2021, Toxicology letters.

Synthesis and anti-inflammatory activity evaluation of a novel series of 6-phenoxy-[1,2,4]triazolo[3,4-a]phthalazine-3-carboxamide derivatives.

Xuejun Jin, Zhe-shan Quan, Guo-Hua Gong, 2016, Bioorganic & medicinal chemistry letters.

Synthesis and evaluation of the HIF-1α inhibitory activity of 3(5)-substituted-4-(quinolin-4-yl)- and 4-(2-phenylpyridin-4-yl)pyrazoles as inhibitors of ALK5.

Juan Ma, Xuejun Jin, H. Piao, 2019, Bioorganic & medicinal chemistry letters.

A quassinoid 6alpha-tigloyloxychaparrinone inhibits hypoxia-inducible factor-1 pathway by inhibition of eukaryotic translation initiation factor 4E phosphorylation.

Dongho Lee, Xuejun Jin, Jung Joon Lee, 2008, European journal of pharmacology.

A novel benzimidazole analogue inhibits the hypoxia-inducible factor (HIF)-1 pathway.

M. Won, K. Chung, Yinglan Jin, 2009, Biochemical and biophysical research communications.

Blockade of TNF-α-induced NF-κB signaling pathway and anti-cancer therapeutic response of dihydrotanshinone I.

Juan Ma, Chunliu Mi, Xuejun Jin, 2015, International immunopharmacology.

Panaxadiol inhibits IL-1β secretion by suppressing zinc finger protein 91-regulated activation of non-canonical caspase-8 inflammasome and MAPKs in macrophages.

Juan Ma, Yue‐Xiao Xing, Zhi Hong Zhang, 2021, Journal of ethnopharmacology.

Mollugin Has an Anti-Cancer Therapeutic Effect by Inhibiting TNF-α-Induced NF-κB Activation

Juan Ma, Chunliu Mi, Zhe Wang, 2017, International journal of molecular sciences.

Baicalein inhibits TNF-α-induced NF-κB activation and expression of NF-κB-regulated target gene products.

Juan Ma, Chunliu Mi, Zhe Wang, 2016, Oncology reports.

Malloapelta B suppresses LPS-induced NF-κB activation and NF-κB-regulated target gene products.

Juan Ma, Chunliu Mi, Xuejun Jin, 2015, International immunopharmacology.

Yangonin blocks tumor necrosis factor-α-induced nuclear factor-κB-dependent transcription by inhibiting the transactivation potential of the RelA/p65 subunit.

J. Nan, Juan Ma, Xuejun Jin, 2012, Journal of pharmacological sciences.

Cucurbitacin B suppresses the transactivation activity of RelA/p65

Xuejun Jin, Jung Joon Lee, N. Dat, 2011, Journal of cellular biochemistry.

Acanthoic acid, a diterpene in Acanthopanax koreanum, protects acetaminophen-induced hepatic toxicity in mice.

J. Nan, Xuejun Jin, Ying-Zi Jiang, 2010, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Blockade of Nuclear Factor-κB Signaling Pathway and Anti-Inflammatory Activity of Cardamomin, a Chalcone Analog from Alpinia conchigera

Young-Soo Hong, Dongho Lee, Xuejun Jin, 2006, Journal of Pharmacology and Experimental Therapeutics.

Hypoxia-inducible factor-1 inhibitory benzofurans and chalcone-derived diels-alder adducts from Morus species.

Young-Soo Hong, Y. H. Kim, Xuejun Jin, 2009, Journal of natural products.

Perillyl alcohol efficiently scavenges activity of cellular ROS and inhibits the translational expression of hypoxia-inducible factor-1α via mTOR/4E-BP1 signaling pathways.

Juan Ma, Chunliu Mi, Xuejun Jin, 2016, International immunopharmacology.

Dihydrotanshinone I inhibits the translational expression of hypoxia-inducible factor-1α.

Juan Ma, Chunliu Mi, Xuejun Jin, 2015, Chemico-biological interactions.

Curcumol inhibits the expression of programmed cell death-ligand 1 through crosstalk between hypoxia-inducible factor-1α and STAT3 (T705) signaling pathways in hepatic cancer.

Juan Ma, Yue‐Xiao Xing, Zhe Wang, 2020, Journal of ethnopharmacology.

Usnic acid suppresses cervical cancer cell proliferation by inhibiting PD‐L1 expression and enhancing T‐lymphocyte tumor‐killing activity

Juan Ma, Yue‐Xiao Xing, Zhi Hong Zhang, 2021, Phytotherapy research : PTR.

Dictamnine promotes apoptosis and inhibits epithelial-mesenchymal transition, migration, invasion and proliferation by downregulating the HIF-1α and Slug signaling pathways.

Juan Ma, Chunliu Mi, Yue‐Xiao Xing, 2018, Chemico-biological interactions.

Celastrol inhibits the HIF-1α pathway by inhibition of mTOR/p70S6K/eIF4E and ERK1/2 phosphorylation in human hepatoma cells.

Liangfeng Han, Juan Ma, Chunliu Mi, 2014, Oncology reports.

Design, synthesis, and screening of novel ursolic acid derivatives as potential anti-cancer agents that target the HIF-1α pathway.

Juan Ma, Xuejun Jin, H. Piao, 2019, Bioorganic & medicinal chemistry letters.

Shikonin suppresses proliferation and induces cell cycle arrest through the inhibition of hypoxia-inducible factor-1α signaling.

Juan Ma, Chunliu Mi, Zhe Wang, 2017, Chemico-biological interactions.

Kamebakaurin inhibits the expression of hypoxia-inducible factor-1α and its target genes to confer antitumor activity.

Juan Ma, Chunliu Mi, Xuejun Jin, 2016, Oncology reports.

Convallatoxin promotes apoptosis and inhibits proliferation and angiogenesis through crosstalk between JAK2/STAT3 (T705) and mTOR/STAT3 (S727) signaling pathways in colorectal cancer.

Juan Ma, Yue‐Xiao Xing, Zhe Wang, 2020, Phytomedicine : international journal of phytotherapy and phytopharmacology.

An Atypical E3 Ligase Zinc Finger Protein 91 Stabilizes and Activates NF-κB-inducing Kinase via Lys63-linked Ubiquitination*

Xuejun Jin, Jung Joon Lee, Ji Hyun Lee, 2010, The Journal of Biological Chemistry.

Zinc-finger protein 91 plays a key role in LIGHT-induced activation of non-canonical NF-κB pathway.

Xuejun Jin, Jung Joon Lee, H. Jin, 2010, Biochemical and biophysical research communications.

Artemisinin inhibits inflammatory response via regulating NF-κB and MAPK signaling pathways

Juan Ma, Chunliu Mi, Zhe Wang, 2017, Immunopharmacology and immunotoxicology.

Dihydromyricetin suppresses TNF-α-induced NF-κB activation and target gene expression

Juan Ma, Chunliu Mi, Xuejun Jin, 2016, Molecular and Cellular Biochemistry.

Amorfrutin A inhibits TNF-α-induced NF-κB activation and NF-κB-regulated target gene products.

Juan Ma, Chunliu Mi, Xuejun Jin, 2014, International immunopharmacology.

Convallatoxin protects against dextran sulfate sodium-induced experimental colitis in mice by inhibiting NF-κB signaling through activation of PPARγ.

Juan Ma, Yue‐Xiao Xing, Zhe Wang, 2019, Pharmacological research.

Zinc finger protein 91 positively regulates the production of IL‐1β in macrophages by activation of MAPKs and non‐canonical caspase‐8 inflammasome

Juan Ma, Chunliu Mi, Zhe Wang, 2018, British journal of pharmacology.

Betulinic acid and betulin ameliorate acute ethanol-induced fatty liver via TLR4 and STAT3 in vivo and in vitro.

J. Nan, Xuejun Jin, Li-Hua Lian, 2013, International immunopharmacology.

Hepatoprotective effect of cryptotanshinone from Salvia miltiorrhiza in D-galactosamine/lipopolysaccharide-induced fulminant hepatic failure.

J. Nan, Xuejun Jin, Li-Hua Lian, 2014, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Arctigenin protects against depression by inhibiting microglial activation and neuroinflammation via HMGB1/TLR4/NF‐κB and TNF‐α/TNFR1/NF‐κB pathways

Juan Ma, Xuejun Jin, L. Piao, 2020, British journal of pharmacology.

Anti-depressive effect of arctiin by attenuating neuroinflammation via HMGB1/TLR4- and TNF-α/TNFR1-mediated NF-κB activation.

Juan Ma, Xuejun Jin, L. Piao, 2020, ACS chemical neuroscience.

Hepatoprotective effects of Sedum sarmentosum on D-galactosamine/lipopolysaccharide-induced murine fulminant hepatic failure.

J. Nan, Xuejun Jin, Jung Joon Lee, 2010, Journal of pharmacological sciences.

Cellular immunopathogenesis in primary Toxoplasma gondii infection during pregnancy

Xuejun Jin, L. Piao, K. Norose, 2018, Parasite immunology.

Excisanin A suppresses proliferation by inhibiting hypoxiainducible factor-1α expression in human hepatocellular carcinoma cells

Liangfeng Han, Chunliu Mi, Zhe Wang, 2021 .

Convallatoxin inhibits IL‐1β production by suppressing zinc finger protein 91 (ZFP91)‐mediated pro‐IL‐1β ubiquitination and caspase‐8 inflammasome activity

Juan Ma, Yue‐Xiao Xing, Zhi Hong Zhang, 2021, British journal of pharmacology.

Ginsenoside Rh2 reduces depression in offspring of mice with maternal toxoplasma infection during pregnancy by inhibiting microglial activation via the HMGB1/TLR4/NF-κB signaling pathway

Juan Ma, Xuejun Jin, L. Piao, 2021, Journal of Ginseng Research.

Arctigenin ameliorates depression-like behaviors in Toxoplasma gondii-infected intermediate hosts via the TLR4/NF-κB and TNFR1/NF-κB signaling pathways.

Juan Ma, Xuejun Jin, L. Piao, 2020, International immunopharmacology.

25-OCH3-PPD induces the apoptosis of activated t-HSC/Cl-6 cells via c-FLIP-mediated NF-κB activation.

J. Nan, Xuejun Jin, Yan-ling Wu, 2011, Chemico-biological interactions.

Blockade of NF- κ B signaling pathway and anti-inflammatory activity of cardamomin, a chalcone analogue from Alpinia conchigera

Young-Soo Hong, Dongho Lee, Xuejun Jin, 2005 .

Acanthoic acid, a diterpene in Acanthopanax koreanum, ameliorates the development of liver fibrosis via LXRs signals.

J. Nan, Xuejun Jin, Li-Hua Lian, 2014, Chemico-biological interactions.

Imperatorin efficiently blocks TNF-α-mediated activation of ROS/PI3K/Akt/NF-κB pathway.

Juan Ma, Chunliu Mi, Zhe Wang, 2017, Oncology reports.

Protective effects of chalcone derivatives for acute liver injury in mice

J. Nan, Xuejun Jin, K. Chai, 2005, Archives of pharmacal research.

Synthesis and evaluation of the HIF-1α inhibitory activities of novel ursolic acid tetrazole derivatives.

Ming-yue Li, Xuejun Jin, H. Piao, 2019, Bioorganic & medicinal chemistry letters.

Phenanthroquinolizidine alkaloids from the roots of Boehmeria pannosa potently inhibit hypoxia-inducible factor-1 in AGS human gastric cancer cells.

Young-Soo Hong, Dongho Lee, Xuejun Jin, 2006, Journal of natural products.

Synthesis and evaluation of the epithelial-to- mesenchymal inhibitory activity of indazole-derived imidazoles as dual ALK5/p38α MAP inhibitors.

Juan Ma, Jing Ying Wang, Xuejun Jin, 2021, European journal of medicinal chemistry.

Synthesis and Evaluation of Chiral Rhodanine Derivatives Bearing Quinoxalinyl Imidazole Moiety as ALK5 Inhibitors.

Xuejun Jin, L. Piao, Tongyi Dou, 2021, Medicinal chemistry (Shariqah (United Arab Emirates)).

A new kaurane diterpenoid from Isodon inflexus

Xuejun Jin, G. Xu, Jung Joon Lee, 2016, Natural product research.

Abietane diterpenes from Salvia miltiorrhiza inhibit the activation of hypoxia-inducible factor-1.

Young-Soo Hong, Dongho Lee, Y. H. Kim, 2007, Journal of natural products.

Ginsenoside Rh2 attenuates microglial activation against toxoplasmic encephalitis via TLR4/NF-κB signaling pathway

Juan Ma, Xuejun Jin, L. Piao, 2019, Journal of ginseng research.

A new benzofuran from Artemisia halodendron Turcz. ex Bess.

Wei Zhou, Xuejun Jin, Cheng-xi Wei, 2019, Natural product research.

Water-extracted Lonicera japonica polysaccharide attenuates allergic rhinitis by regulating NLRP3-IL-17 signaling axis.

Xuejun Jin, Xinyu Bai, Ping Liu, 2022, Carbohydrate polymers.

Resveratrol modulates Toxoplasma gondii infection induced liver injury by intervening in the HMGB1/TLR4/NF-κB signaling pathway.

Juan Ma, Xuejun Jin, L. Piao, 2021, European journal of pharmacology.

Arctigenin exhibits hepatoprotective activity in Toxoplasma gondii-infected host through HMGB1/TLR4/NF-κB pathway.

Juan Ma, Xuejun Jin, L. Piao, 2020, International immunopharmacology.

Ginsengenin derivatives synthesized from 20(R)-panaxotriol: Synthesis, characterization, and antitumor activity targeting HIF-1 pathway

Xuejun Jin, Jung Joon Lee, Dongzhou Kang, 2022, Journal of ginseng research.

Design, synthesis of novel celastrol derivatives and study on their antitumor growth through HIF-1α pathway.

Jing Ying Wang, Xuejun Jin, Qian Xu, 2021, European journal of medicinal chemistry.

Cryptotanshinone inhibits LPS-induced proinflammatory mediators via TLR4 and TAK1 signaling pathway.

J. Nan, Xuejun Jin, Li-Hua Lian, 2011, International immunopharmacology.

Design, synthesis, and evaluation of novel ursolic acid derivatives as HIF-1α inhibitors with anticancer potential.

Xuejun Jin, H. Piao, Zhi-Yu Wei, 2017, Bioorganic chemistry.

Synthesis of (aryloxyacetylamino)-isonicotinic/nicotinic acid analogues as potent hypoxia-inducible factor (HIF)-1alpha inhibitors.

Young-Soo Hong, Yinglan Jin, Xuejun Jin, 2007, Bioorganic & medicinal chemistry letters.

An isoaurone and other constituents from Trichosanthes kirilowii seeds inhibit hypoxia-inducible factor-1 and nuclear factor-kappaB.

Young-Soo Hong, Xuejun Jin, Jung Joon Lee, 2010, Journal of natural products.

Panaxadiol inhibits programmed cell death-ligand 1 expression and tumour proliferation via hypoxia-inducible factor (HIF)-1α and STAT3 in human colon cancer cells.

Juan Ma, Zhe Wang, Zhi Hong Zhang, 2020, Pharmacological research.

Licochalcone A inhibits proliferation and promotes apoptosis of colon cancer cell by targeting programmed cell death-ligand 1 via the NF-κB and Ras/Raf/MEK pathways.

Juan Ma, H. Zuo, Xuejun Jin, 2021, Journal of ethnopharmacology.

Chelidonine inhibits TNF‐α‐induced inflammation by suppressing the NF‐κB pathways in HCT116 cells

Juan Ma, Chunliu Mi, Zhe Wang, 2018, Phytotherapy research : PTR.

4',6-Dihydroxy-4-methoxyisoaurone inhibits TNF-α-induced NF-κB activation and expressions of NF-κB-regulated target gene products.

Juan Ma, Chunliu Mi, Xuejun Jin, 2016, Journal of pharmacological sciences.

Cryptopleurine Targets NF-κB Pathway, Leading to Inhibition of Gene Products Associated with Cell Survival, Proliferation, Invasion, and Angiogenesis

J. Nan, Xuejun Jin, Jung Joon Lee, 2012, PloS one.

Anti-Tumor Effects of Carrimycin and Monomeric Isovalerylspiramycin I on Hepatocellular Carcinoma in Vitro and in Vivo

Juan Ma, Zhi Hong Zhang, Ming Yue Li, 2021, Frontiers in Pharmacology.

Narirutin exerts anti‐inflammatory activity by inhibiting NLRP3 inflammasome activation in macrophages

Juan Ma, Ming Yue Li, H. Zuo, 2023, Phytotherapy research : PTR.

Formononetin represses cervical tumorigenesis by interfering with the activation of PD-L1 through MYC and STAT3 downregulation.

Juan Ma, Yue‐Xiao Xing, Zhi Hong Zhang, 2021, The Journal of nutritional biochemistry.

Cucurbitacin B inhibits the translational expression of hypoxia-inducible factor-1α.

Juan Ma, Chunliu Mi, Xuejun Jin, 2014, European journal of pharmacology.

A homogeneous Lonicera japonica polysaccharide alleviates atopic dermatitis by promoting Nrf2 activation and NLRP3 inflammasome degradation via p62.

Xuejun Jin, Xinyu Bai, Hengyan Shen, 2023, Journal of ethnopharmacology.

Amorfrutin A inhibits TNF-α induced JAK/STAT signaling, cell survival and proliferation of human cancer cells

Juan Ma, Chunliu Mi, Zhe Wang, 2017, Immunopharmacology and immunotoxicology.

A diterpenoid acanthoic acid from Acanthopanax koreanum protects against D-galactosamine/lipopolysaccharide-induced fulminant hepatic failure in mice.

J. Nan, Xuejun Jin, Jung Joon Lee, 2008, Biological & pharmaceutical bulletin.

A new ribonucleotide from Cordyceps militaris

X. Wang, Wei Zhou, Xuejun Jin, 2017, Natural product research.

Tetrahydropalmatine inhibits lipid accumulation through AMPK signaling pathway in 3T3‑L1 adipocytes.

Hai-Dan Yuan, Guangchun Piao, Xuejun Jin, 2017, Molecular medicine reports.

A new biflavonoid from the whole herb of Lepisorus ussuriensis

Wei Zhou, Xuejun Jin, Gao Li, 2016, Natural product research.

Erianin regulates programmed cell death ligand 1 expression and enhances cytotoxic T lymphocyte activity.

Juan Ma, Yue‐Xiao Xing, Zhi Hong Zhang, 2020, Journal of ethnopharmacology.

Sertraline ameliorates inflammation in CUMS mice and inhibits TNF-α-induced inflammation in microglia cells.

Juan Ma, Xuejun Jin, L. Piao, 2019, International immunopharmacology.

Regulatory mechanisms of natural compounds from traditional Chinese herbal medicines on the microglial response in ischemic stroke.

Juan Ma, Ming Yue Li, H. Zuo, 2023, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Zinc finger protein 91 (ZFP91) activates HIF-1α via NF-κB/p65 to promote proliferation and tumorigenesis of colon cancer

Juan Ma, Chunliu Mi, Xuejun Jin, 2016, Oncotarget.

Celastrol induces the apoptosis of breast cancer cells and inhibits their invasion via downregulation of MMP-9.

Liangfeng Han, Juan Ma, Chunliu Mi, 2014, Oncology reports.

Development of natural products for anti-PD-1/PD-L1 immunotherapy against cancer.

Juan Ma, Xuejun Jin, MyongHak Ri, 2021, Journal of ethnopharmacology.

Britannin stabilizes T cell activity and inhibits proliferation and angiogenesis by targeting PD-L1 via abrogation of the crosstalk between Myc and HIF-1α in cancer.

Juan Ma, Zhi Hong Zhang, Ming Yue Li, 2020, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Galangin inhibits programmed cell death-ligand 1 expression by suppressing STAT3 and MYC and enhances T cell tumor-killing activity.

Juan Ma, Ming Yue Li, H. Zuo, 2023, Phytomedicine : international journal of phytotherapy and phytopharmacology.

(Aryloxyacetylamino)benzoic acid analogues: A new class of hypoxia-inducible factor-1 inhibitors.

Young-Soo Hong, Yinglan Jin, Xuejun Jin, 2007, Journal of medicinal chemistry.

Synthesis and evaluation of HIF-1α inhibitory activities of novel panaxadiol derivatives.

Xuejun Jin, H. Piao, Yuqing Zhao, 2020, Bioorganic & Medicinal Chemistry Letters.

Cryptotanshinone inhibits LPS-induced proinflammatory mediators via TLR4 and TAK1 signaling pathway.

J. Nan, Xuejun Jin, Li-Hua Lian, 2011, International immunopharmacology.

Cucurbitacin B inhibits the translational expression of hypoxia-inducible factor-1α.

Juan Ma, Chunliu Mi, Xuejun Jin, 2014, European journal of pharmacology.

Betulinic acid inhibits the proliferation of human laryngeal carcinoma cells through reactive oxygen species-mediate mitochondrial apoptotic pathway.

Xuejun Jin, Huamin Zhang, Mengru Zhou, 2023, Toxicology in vitro : an international journal published in association with BIBRA.

Celastrol induces the apoptosis of breast cancer cells and inhibits their invasion via downregulation of MMP-9.

Liangfeng Han, Juan Ma, Chunliu Mi, 2014, Oncology reports.