H. Querfurth

发表

mTORC2 (Rictor) in Alzheimer's Disease and Reversal of Amyloid-β Expression-Induced Insulin Resistance and Toxicity in Rat Primary Cortical Neurons.

C. Lemere, S. M. de la Monte, Han-Kyu Lee, 2017, Journal of Alzheimer's disease : JAD.

Predicting Alzheimer’s disease progression using multi-modal deep learning approach

Sterling C. Johnson, David T. Jones, Nick C Fox, 2019, Scientific Reports.

Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease

Alan C. Evans, Sterling C. Johnson, Keith A. Johnson, 2019, bioRxiv.

Vaccine-associated paralytic poliomyelitis. Regional case series and review.

H. Querfurth, P. Swanson, 1990, Archives of neurology.

Prediction of intracranial pressure from noninvasive transocular venous and arterial hemodynamic measurements

T. Steiner, S. Arms, H. Querfurth, 2004, Neurocritical care.

Caffeine Stimulates Amyloid β‐Peptide Release from β‐Amyloid Precursor Protein‐Transfected HEK293 Cells

D. Selkoe, H. Querfurth, Jin-hong Jiang, 1997 .

Increased intraneuronal resting [Ca2+] in adult Alzheimer’s disease mice

F. LaFerla, H. Querfurth, S. Oddo, 2008, Journal of neurochemistry.

Amyloid-β protein impairs Ca2+ release and contractility in skeletal muscle

C. Ward, F. LaFerla, M. Kitazawa, 2010, Neurobiology of Aging.

A semi-mechanism approach based on MRI and proteomics for prediction of conversion from mild cognitive impairment to Alzheimer’s disease

Sterling C. Johnson, David T. Jones, Nick C Fox, 2016, Scientific Reports.

Robust Identification of Alzheimer’s Disease subtypes based on cortical atrophy patterns

Norbert Schuff, Robert C. Green, Andrew J. Saykin, 2017 .

Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis

Norbert Schuff, Michael W. Weiner, Robert C. Green, 2016, Nature Communications.

Alzheimer's disease.

F. LaFerla, H. Querfurth, Frank M. LaFerla, 2010, The New England journal of medicine.

Action potential patterns of isolated frog muscle spindle in response to sinusoidal stimulation.

H. Querfurth, 1985, Journal of neurophysiology.

Information transmission by isolated frog muscle spindle

R. Eckhorn, R. Eckhorn, H. Querfurth, 1985, Biological Cybernetics.

The transducer and encoder of frog muscle spindles are essentially nonlinear. Physiological conclusions from a white-noise analysis

H. Querfurth, B. Pöpel, 1984, Biological Cybernetics.

Intraneuronal β-Amyloid Expression Downregulates the Akt Survival Pathway and Blunts the Stress Response

K. Walsh, H. Querfurth, G. Gouras, 2005, The Journal of Neuroscience.

Author Correction: Multimodal hippocampal subfield grading for Alzheimer’s disease classification

Norbert Schuff, Michael W. Weiner, Robert C. Green, 2020, Scientific Reports.

Synergistic effects of β-amyloid and ceramide-induced insulin resistance on mitochondrial metabolism in neuronal cells.

Han-Kyu Lee, Bumsup Kwon, H. Querfurth, 2015, Biochimica et biophysica acta.

Encoder response of isolated frog muscle spindle elicited by pseudorandom noise stimuli.

H. Querfurth, 1986, Journal of neurophysiology.

Enhancer function and novel DNA binding protein activity in the near upstream betaAPP gene promoter.

D. Selkoe, H. Querfurth, W. Xia, 1999, Gene.

Heat shock protein 70 participates in the neuroprotective response to intracellularly expressed beta-amyloid in neurons.

K. Walsh, H. Querfurth, Roy C. Smith, 2004, The Journal of neuroscience : the official journal of the Society for Neuroscience.

The injury-induced myokine insulin-like 6 is protective in experimental autoimmune myositis

Kazuto Nakamura, I. Adham, K. Walsh, 2014, Skeletal Muscle.

Opposite effects of saturated and unsaturated free fatty acids on intracellular signaling and metabolism in neuronal cells

Bumsup Kwon, H. Querfurth, 2014 .

The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory

Sterling C. Johnson, Keith A. Johnson, Joanne L. Lord, 2019, Nature Communications.

Ophthalmodynamometry for ICP prediction and pilot test on Mt. Everest

Steven W. Mundell, P. Lieberman, S. Arms, 2010, BMC neurology.

Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volume

Sterling C. Johnson, Keith A. Johnson, Raymond Scott Turner, 2022, GeroScience.

Aβ42 generation is toxic to endothelial cells and inhibits eNOS function through an Akt/GSK-3β signaling-dependent mechanism

K. Walsh, Hyo‐Soo Kim, T. Suhara, 2003, Neurobiology of Aging.

Abeta42 generation is toxic to endothelial cells and inhibits eNOS function through an Akt/GSK-3beta signaling-dependent mechanism.

K. Walsh, Hyo‐Soo Kim, T. Suhara, 2003, Neurobiology of aging.

Downregulation and increased turnover of β-amyloid precursor protein in skeletal muscle cultures by neuregulin-1

B. Ford, H. Querfurth, K. Rosen, 2003, Experimental Neurology.

Parkin reverses intracellular β‐amyloid accumulation and its negative effects on proteasome function

C. Moussa, Han-Kyu Lee, H. Querfurth, 2010, Journal of neuroscience research.

The Insulin/Akt Signaling Pathway Is Targeted by Intracellular -Amyloid

Han-Kyu Lee, H. Querfurth, Pravir Kumar, 2009 .

An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease

Sterling C. Johnson, Keith A. Johnson, Raymond Scott Turner, 2022, Nature Aging.

Parkin Protects against Mitochondrial Toxins and β-Amyloid Accumulation in Skeletal Muscle Cells*

Kenneth M. Rosen, Matthew S. Goldberg, C. Moussa, 2006, Journal of Biological Chemistry.

Parkin promotes intracellular Ab1–42 clearance

L. Zhang, C. Moussa, H. Querfurth, 2009 .

Palmitate activates mTOR/p70S6K through AMPK inhibition and hypophosphorylation of raptor in skeletal muscle cells: Reversal by oleate is similar to metformin.

Bumsup Kwon, H. Querfurth, 2015, Biochimie.

Foxo/Atrogin induction in human and experimental myositis

K. Walsh, Ling Zeng, Han-Kyu Lee, 2012, Neurobiology of Disease.

β-Amyloid Peptide Expression Is Sufficient for Myotube Death: Implications for Human Inclusion Body Myopathy

Kenneth M. Rosen, R. Neve, Y. Fujio, 2001, Molecular and Cellular Neuroscience.

Increased amyloid β-peptide uptake in skeletal muscle is induced by hyposialylation and may account for apoptosis in GNE myopathy

H. Querfurth, M. Bosch-Morató, F. Muñoz, 2016, Oncotarget.

Transgenic expression of B‐APP in fast‐twitch skeletal muscle leads to calcium dyshomeostasis and IBM‐like pathology

Pravir Kumar, F. LaFerla, K. Walsh, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Hexanucleotide repeat expansions in C9ORF72 in the spectrum of motor neuron diseases

Sterling C. Johnson, Nick C Fox, Keith A. Johnson, 2012, Neurology.

Cognitive Impairments Preceding and Outlasting Autoimmune Limbic Encephalitis

Jennifer D. Davis, H. Querfurth, R. Gross, 2016, Case reports in neurological medicine.

Amyloid-β protein impairs Ca2+ release and contractility in skeletal muscle

C. Ward, F. LaFerla, M. Kitazawa, 2009, Neurobiology of Aging.

Heat Shock Protein 70 Participates in the Neuroprotective Response to Intracellularly Expressed (cid:1) -Amyloid in Neurons

H. Querfurth, Roy C. Smith, K. Walsh, 2004 .

Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits

Norbert Schuff, Michael W. Weiner, Robert C. Green, 2016, Scientific Reports.

Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer’s disease

Nick C Fox, Keith A. Johnson, Raymond Scott Turner, 2022, Nature Communications.

Subject Index Vol. 11, 2000

M. Tovée, J. Rusted, P. Hof, 2000, Dementia and Geriatric Cognitive Disorders.

Flow velocity and pulsatility of the ocular circulation in chronic intracranial hypertension

P. Heggerick, W. Lagrèze, H. Querfurth, 2002, Acta neurologica Scandinavica.

A PDK-1 allosteric agonist improves spatial learning and memory in a βAPP/PS-1 transgenic mouse-high fat diet intervention model of Alzheimer's disease

H. Querfurth, A. Slitt, Nathan O. Surles, 2022, Behavioural Brain Research.

Expression of ryanodine receptors in human embryonic kidney (HEK293) cells.

D. Golan, H. Querfurth, P. Yacono, 1998, The Biochemical journal.

Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans

Norbert Schuff, Adrian Preda, John Kornak, 2012, Proceedings of the National Academy of Sciences.

Correlation between Alzheimer’s disease and type 2 diabetes using non-negative matrix factorization

Keith A. Johnson, Raymond Scott Turner, Joanne L. Lord, 2021, Scientific Reports.

Women can bear a bigger burden: ante- and post-mortem evidence for reserve in the face of tau

Sterling C. Johnson, Nick C Fox, John X. Morris, 2020, Brain communications.

The impact of PICALM genetic variations on reserve capacity of posterior cingulate in AD continuum

Sterling C. Johnson, Keith A. Johnson, Joanne L. Lord, 2016, Scientific Reports.

Effect of CR1 Genetic Variants on Cerebrospinal Fluid and Neuroimaging Biomarkers in Healthy, Mild Cognitive Impairment and Alzheimer's Disease Cohorts

Keith A. Johnson, Joanne L. Lord, Colleen S. Albers, 2016, Molecular Neurobiology.

Sodium channels in normal and regenerated feline ventral spinal roots

R. Herndon, H. Querfurth, R. Armstrong, 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Cavernous Sinus and Leptomeningeal Metastases Arising from a Squamous Cell Carcinoma of the Face: Case Report

J. Fletcher, Jay-Jiguang Zhu, H. Querfurth, 2004, Neurosurgery.

Mammalian/mechanistic target of rapamycin (mTOR) complexes in neurodegeneration

Han-Kyu Lee, H. Querfurth, 2021, Molecular neurodegeneration.

Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology

Sterling C. Johnson, David T. Jones, Taylor W. Schmitz, 2016, Nature Communications.

Ferritin levels in the cerebrospinal fluid predict Alzheimer’s disease outcomes and are regulated by APOE

Keith A. Johnson, Scott Ayton, Joanne L. Lord, 2015, Nature Communications.

Calcium ionophore increases amyloid beta peptide production by cultured cells.

D. Selkoe, H. Querfurth, 1994, Biochemistry.

Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways

Keith A. Johnson, Raymond Scott Turner, Sherye A. Sirrel, 2016, Scientific Reports.

Cross‐functional E3 ligases Parkin and C‐terminus Hsp70‐interacting protein in neurodegenerative disorders

H. Querfurth, Pravir Kumar, R. K. Ambasta, 2012, Journal of neurochemistry.

Oleate prevents palmitate-induced mitochondrial dysfunction, insulin resistance and inflammatory signaling in neuronal cells.

Han-Kyu Lee, Bumsup Kwon, H. Querfurth, 2014, Biochimica et biophysica acta.

Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease

Sterling C. Johnson, Christine L. Tardif, John X. Morris, 2021, Nature Communications.

Differential Effects of Mitochondrial Heat Shock Protein 60 and Related Molecular Chaperones to Prevent Intracellular β-Amyloid-induced Inhibition of Complex IV and Limit Apoptosis*

H. Querfurth, Pravir Kumar, R. Mestril, 2006, Journal of Biological Chemistry.

Non-coding variability at the APOE locus contributes to the Alzheimer’s risk

Sterling C. Johnson, Keith A. Johnson, Raymond Scott Turner, 2019, Nature Communications.

Four distinct trajectories of tau deposition identified in Alzheimer’s disease

Sterling C. Johnson, John X. Morris, Keith A. Johnson, 2021, Nature Medicine.

Mining Outcome-relevant Brain Imaging Genetic Associations via Three-way Sparse Canonical Correlation Analysis in Alzheimer’s Disease

Michael W. Weiner, Robert C. Green, Shannon L. Risacher, 2017, Scientific Reports.

Predicting Alzheimer’s disease progression using multi-modal deep learning approach

Keith A. Johnson, Sherye A. Sirrel, Alice D. Brown, 2019, Scientific Reports.

Dissociation of tau pathology and neuronal hypometabolism within the ATN framework of Alzheimer’s disease

Sterling C. Johnson, Keith A. Johnson, Raymond Scott Turner, 2022, Nature Communications.

The insulin/Akt signaling pathway is targeted by intracellular beta-amyloid.

Pravir Kumar, Han-Kyu Lee, H. Querfurth, 2009, Molecular biology of the cell.

Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer’s disease

Andrew J. Saykin, Arthur W. Toga, Qianjin Feng, 2017, Scientific Reports.

Dissociation of ERK and Akt signaling in endothelial cell angiogenic responses to beta-amyloid.

H. Querfurth, K. Rosen, Vimal Veereshwarayya, 2006, Experimental cell research.

Effect of CLU genetic variants on cerebrospinal fluid and neuroimaging markers in healthy, mild cognitive impairment and Alzheimer’s disease cohorts

Keith A. Johnson, Raymond Scott Turner, Sherye A. Sirrel, 2016, Scientific Reports.

Beta APP mRNA transcription is increased in cultured fibroblasts from the familial Alzheimer's disease-1 family.

E. Wijsman, P. S. St George-Hyslop, D. Selkoe, 1995, Brain research. Molecular brain research.

Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease

Keith A. Johnson, Charles D. Smith, Sherye A. Sirrel, 2020, Nature Communications.

KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease

Sterling C. Johnson, Keith A. Johnson, Raymond Scott Turner, 2021, Nature Communications.

Calcium Dyshomeostasis in β-Amyloid and Tau-bearing Skeletal Myotubes*

P. Allen, H. Querfurth, José R Lopez, 2004, Journal of Biological Chemistry.

Heat Shock Proteins, Unfolded Protein Response Chaperones and Alzheimer’s Disease

H. Querfurth, J. Magrané, 2008 .

Pathogenic accumulation of APP in fast twitch muscle of IBM patients and a transgenic model

Vincent J. Caiozzo, F. LaFerla, M. Kitazawa, 2006, Neurobiology of Aging.

Heat Shock Protein 70 Participates in the Neuroprotective Response to Intracellularly Expressed β-Amyloid in Neurons

K. Walsh, H. Querfurth, Roy C. Smith, 2004, The Journal of Neuroscience.

Parkin promotes intracellular Abeta1-42 clearance.

Lihua Zhang, L. Zhang, C. Moussa, 2009, Human molecular genetics.

Multiple effects of β-amyloid on single excitatory synaptic connections in the PFC

Yun Wang, L. Hlatky, H. Querfurth, 2013, Front. Cell. Neurosci..

Opposite Effects of Low and High Doses of Aβ42 on Electrical Network and Neuronal Excitability in the Rat Prefrontal Cortex

Yun Wang, H. Querfurth, Guangping Zhang, 2009, PloS one.

CHIP and HSPs interact with β-APP in a proteasome-dependent manner and influence Aβ metabolism

K. Kosik, C. Patterson, H. Band, 2007 .

CHIP and HSPs interact with beta-APP in a proteasome-dependent manner and influence Abeta metabolism.

K. Kosik, C. Patterson, H. Band, 2007, Human molecular genetics.

A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer’s Disease Data

Norbert Schuff, Michael W. Weiner, Andrew J. Saykin, 2019, Scientific Reports.

The trend of disruption in the functional brain network topology of Alzheimer’s disease

Sterling C. Johnson, Keith A. Johnson, Raymond Scott Turner, 2021, Scientific Reports.

Multimodal and Multiscale Deep Neural Networks for the Early Diagnosis of Alzheimer’s Disease using structural MR and FDG-PET images

Adrian Preda, Evan Fletcher, Godfrey Pearlson, 2018, Scientific Reports.

Glucose metabolism patterns: A potential index to characterize brain ageing and predict high conversion risk into cognitive impairment

Keith A. Johnson, Raymond Scott Turner, Sherye A. Sirrel, 2022, GeroScience.

Regional Amyloid-β Load and White Matter Abnormalities Contribute to Hypometabolism in Alzheimer’s Dementia

Sterling C. Johnson, Keith A. Johnson, Charles D. Smith, 2018, Molecular Neurobiology.

Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

Nick C Fox, Keith A. Johnson, Raymond Scott Turner, 2017, Nature Communications.

Aberrant cell cycle reentry in human and experimental inclusion body myositis and polymyositis.

K. Walsh, Ling Zeng, Han-Kyu Lee, 2014, Human molecular genetics.

Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction

Keith A. Johnson, Raymond Scott Turner, Sherye A. Sirrel, 2023, Communications Medicine.

The injury-induced myokine insulin-like 6 is protective in experimental autoimmune myositis

Kazuto Nakamura, I. Adham, K. Walsh, 2014, Skeletal Muscle.

Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Keith A. Johnson, Raymond Scott Turner, Charles D. Smith, 2022, Nature Aging.

A PDK-1 allosteric agonist neutralizes insulin signaling derangements and beta-amyloid toxicity in neuronal cells and in vitro

M. Rioult-Pedotti, K. Parang, R. Tiwari, 2022, PloS one.

Calcium dyshomeostasis in beta-amyloid and tau-bearing skeletal myotubes.

Paul D Allen, P. Allen, H. Querfurth, 2004, The Journal of biological chemistry.

mTOR Mysteries: Nuances and Questions About the Mechanistic Target of Rapamycin in Neurodegeneration

H. Querfurth, N. Norwitz, Nicholas G. Norwitz, 2020, Frontiers in Neuroscience.

Mammalian target of rapamycin complexes

Han-Kyu Lee, H. Querfurth, 2020, Genetics, Neurology, Behavior, and Diet in Dementia.

Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer’s Disease via Fusion of Clinical, Imaging and Omic Features

Adrian Preda, Evan Fletcher, Charles DeCarli, 2017, Scientific Reports.

Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states

Islem Rekik, Mohamed Ali Mahjoub, Keith A. Johnson, 2018, Scientific Reports.

The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory

Keith A. Johnson, Raymond Scott Turner, Sherye A. Sirrel, 2019, Nature Communications.

Acetylcholinesterase Inhibition in Dementia with Lewy Bodies: Results of a Prospective Pilot Trial

H. Querfurth, G. J. Allam, M. A. Geffroy, 2000, Dementia and Geriatric Cognitive Disorders.

A telescope GWAS analysis strategy, based on SNPs-genes-pathways ensamble and on multivariate algorithms, to characterize late onset Alzheimer’s disease

Sterling C. Johnson, Keith A. Johnson, Sherye A. Sirrel, 2020, Scientific Reports.

Caffeine stimulates amyloid beta-peptide release from beta-amyloid precursor protein-transfected HEK293 cells.

D. Selkoe, H. Querfurth, J. Geiger, 1997, Journal of neurochemistry.

Multimodal and Multiscale Deep Neural Networks for the Early Diagnosis of Alzheimer's Disease using structural MR and FDG-PET images

Sterling C. Johnson, Mirza Faisal Beg, Karteek Popuri, 2017, ArXiv.

Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease

Sterling C. Johnson, Keith A. Johnson, Charles D. Smith, 2020, Nature Communications.

Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways

John X. Morris, Keith A. Johnson, Raymond Scott Turner, 2019, Scientific Reports.

GenEpi: gene-based epistasis discovery using machine learning

Michael W. Weiner, Yen-Jen Oyang, Arthur W. Toga, 2018, BMC Bioinformatics.

A blood-based signature of cerebrospinal fluid Aβ1–42 status

John X. Morris, Keith A. Johnson, Raymond Scott Turner, 2019, Scientific Reports.

Characteristic patterns of inter- and intra-hemispheric metabolic connectivity in patients with stable and progressive mild cognitive impairment and Alzheimer’s disease

Keith A. Johnson, Raymond Scott Turner, Sherye A. Sirrel, 2018, Scientific Reports.

Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients

Sterling C. Johnson, Keith A. Johnson, Raymond Scott Turner, 2022, Nature Aging.

Effect of CLU genetic variants on cerebrospinal fluid and neuroimaging markers in healthy, mild cognitive impairment and Alzheimer’s disease cohorts

Sterling C. Johnson, Raymond Scott Turner, Sherye A. Sirrel, 2016, Scientific Reports.

A blood-based signature of cerebrospinal fluid Aβ1–42 status

Raymond Scott Turner, Sherye A. Sirrel, Alice D. Brown, 2019, Scientific Reports.

Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE

Sterling C. Johnson, Sherye A. Sirrel, Alice D. Brown, 2015, Nature Communications.

New onset seizures in a patient with Long QT Syndrome (LQTS2) and a pathogenic carboxyl-terminus frameshift variant of the KCNH2 gene

H. Querfurth, Katherine A. Zarroli, 2018, Journal of Clinical Neuroscience.

Receptor potentials of isolated frog muscle spindle evoked by sinusoidal stimulation.

H. Querfurth, 1985, Journal of neurophysiology.

Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration

Sterling C. Johnson, Raymond Scott Turner, Alice D. Brown, 2020, Molecular neurodegeneration.

Processing vibratory stimuli in isolated frog muscle spindle

H. Querfurth, 2004, Experimental Brain Research.

Action‐potential initiation and maintained activity of the isolated frog muscle spindle

H. Querfurth, 2006, The European journal of neuroscience.

Aberrant cell cycle reentry in human and experimental inclusion body myositis and polymyositis.

K. Walsh, Ling Zeng, Han-Kyu Lee, 2014, Human molecular genetics.

Robust Identification of Alzheimer’s Disease subtypes based on cortical atrophy patterns

Sterling C. Johnson, David T. Jones, Nick C Fox, 2017, Scientific Reports.