T. Shinada

发表

Oosorption in the stink bug Plautia stali: role of Juvenile hormone in the induction of oosorption

T. Kotaki, Kanako Kaihara, Yumi Ando, 2016 .

An efficient synthesis of α-acyloxyketone by Cu(acac)2-catalyzed insertion reaction of α-diazoketone to carboxylic acid

T. Shinada, H. Sakai, Y. Ohfune, 1998 .

Characterization of Class IB terpene synthase: the first crystal structure bound with substrate surrogate.

K. Miki, T. Shinada, M. Fujihashi, 2020, ACS chemical biology.

Structure Determination of Monomeric Phloroglucinol Derivatives with a Cinnamoyl Group Isolated from Propolis of the Stingless Bee, Tetragonula carbonaria

T. Shinada, R. Tanaka, K. Amano, 2016 .

Novel biologically active peptides from the venom of Polistes rothneyi iwatai.

T. Shinada, H. Naoki, T. Nakajima, 2006, Biological & pharmaceutical bulletin.

1,2-dioxo-3-isopropyloxy-4-methyl-3-cyclobutene as a nucleophilic synthon. Synthesis of Sq-containing cinnamic acid derivatives

T. Shinada, Y. Ohfune, K. Hayashi, 2002 .

Olefination of dialkyl squarates by wittig and horner-emmons reactions. A facile synthesis of 3,4-dioxo-1-cyclobutene-1-acetic acid esters

T. Shinada, K. Sakaguchi, Y. Ohfune, 1997 .

Indium-mediated asymmetric Barbier-type allylation of aldimines in alcoholic solvents: synthesis of optically active homoallylic amines.

T. Shinada, T. Vilaivan, Y. Ohfune, 2005, The Journal of organic chemistry.

Asymmetric Strecker Route toward the Synthesis of Biologically Active α,α-Disubstituted α-Amino Acids

T. Shinada, Y. Ohfune, 2003 .

Burkholderia gut symbiont modulates titer of specific juvenile hormone in the bean bug Riptortus pedestris.

T. Kotaki, T. Shinada, Jin-Wook Yoo, 2019, Developmental and comparative immunology.

Diverse Aromatic Metabolites in the Solitary Tunicate Cnemidocarpa irene.

R. Sakai, T. Shinada, M. Fujita, 2020, Journal of natural products.

Total synthesis of (−)-amathaspiramide F

T. Shinada, T. Okada, K. Sakaguchi, 2009 .

Molecular Basis for Enzymatic Aziridine Formation via Sulfate Elimination.

M. Nishiyama, T. Shinada, S. Kosono, 2022, Journal of the American Chemical Society.

Crystal structure and functional analysis of large-terpene synthases belonging to a newly found subclass† †Electronic supplementary information (ESI) available: One PDF document and three movie files. See DOI: 10.1039/c8sc00289d

K. Miki, T. Shinada, M. Fujihashi, 2018, Chemical science.

Effect of Asiasarum Root Extract and Its Constituents on Interleukin-1β-Stimulated Matrix Metalloproteinase-1 Secretion from Human Gingival Fibroblasts.

T. Shinada, H. Matsuda, K. Murata, 2016, Biological & pharmaceutical bulletin.

Short total synthesis of (-)-kainic acid.

T. Shinada, Y. Ohfune, K. Oe, 2014, Organic letters.

Biosynthesis of Phytosiderophores, Mugineic Acids, Associated with Methionine Cycling (*)

T. Shinada, K. Nomoto, J. Ma, 1995, The Journal of Biological Chemistry.

Au(I)-catalyzed efficient synthesis of α-acyloxy-α′-silyl ketones from α-acyloxy-α-alkynylsilanes

T. Shinada, T. Okada, K. Sakaguchi, 2008 .

Asymmetric construction of two contiguous stereocenters by diastereoface differentiating addition reaction of thiols to chiral imides: Formal synthesis of (+)-diltiazem

T. Shinada, O. Miyata, T. Naito, 1997 .

A new entry for the synthesis of N-acyl-N′-substituted guanidines

T. Shinada, Y. Ohfune, T. Ando, 2006 .

Asymmetric induction at two contiguous stereogenic centers by diastereoface differentiating nucleophilic addition reaction

T. Shinada, O. Miyata, T. Naito, 1991 .

A NEW STEREOSELECTIVE ROUTE TO γ-BUTYROLACTONES : ASYMMETRIC SYNTHESES OF (+)-trans-WHISKY AND (+)-trans-COGNAC LACTONES

T. Shinada, O. Miyata, T. Naito, 1992 .

Synthesis of fluorine analogues of protoporphyrin potentially useful for diagnosis and therapy of tumors.

T. Shinada, H. Sato, T. Nagai, 1990, Chemical & pharmaceutical bulletin.

An Aromatic Farnesyltransferase Functions in Biosynthesis of the Anti-HIV Meroterpenoid Daurichromenic Acid1

T. Shinada, F. Taura, Y. Asakawa, 2018, Plant Physiology.

A facile method for the conversion of oximes to ketones and aldehydes by the use of activated MnO2

T. Shinada, K. Yoshihara, 1995 .

Au-catalyzed cyclization of allenylsilanes. Regioselective conversion to 2-amino-4-silylmethylene γ-butyrolactone

T. Shinada, T. Okada, K. Sakaguchi, 2011 .

Total synthesis and structure elucidation of (±)-triumphalone and (±)-isotriumphalone

T. Shinada, Y. Ohfune, E. Nishimura, 2015 .

Enantio‐ and Diastereoselective Construction of α,α‐Disubstituted α‐Amino Acids for the Synthesis of Biologically Active Compounds

T. Shinada, Y. Ohfune, 2005 .

Indium mediated Barbier-type allylation of aldimines in alcoholic solvents

T. Shinada, T. Vilaivan, Y. Ohfune, 2001 .

Selective oxidation of alcohol-d1 to aldehyde-d1 using MnO2

T. Shinada, Yuki Yamamoto, Y. Yasuno, 2021, RSC advances.

N-Acylcarbazole as a Selective Transamidation Reagent

T. Shinada, T. Satoh, M. Kuse, 2020 .

Synthesis of Indenones through Rhodium(III)-catalyzed [3+2] Annulation Utilizing a Recyclable Carbazolyl Leaving Group

T. Shinada, T. Satoh, Asumi Sakai, 2021 .

Total synthesis of (-)-kaitocephalin.

T. Shinada, M. Kawasaki, Y. Ohfune, 2005, Organic letters.

Synthesis of leucine-enkephalin analogs containing α-amino squaric acid

T. Shinada, Y. Shigeri, Y. Ohfune, 2007 .

Total synthesis of (−)-funebrine via Au-catalyzed regio- and stereoselective γ-butyrolactonization of allenylsilane

T. Shinada, T. Okada, K. Sakaguchi, 2011 .

Efficient total synthesis of manzacidin B

T. Shinada, Y. Ohfune, K. Oe, 2012 .

Direct conversion of 1,2-diol into allyl sulfide. Regioselective transformation of (−)-quinic acid to (−)-shikimic acid

T. Shinada, Y. Ohfune, Y. Yoshida, 1998 .

Synthesis of novel amino squaric acids via addition of dianion enolates derived from N-Boc amino acid esters

T. Shinada, Y. Ohfune, Toshikazu Ishida, 2005 .

On the Stereoselectivity of Asymmetric Strecker Synthesis in a Cyclohexane System : Synthesis of Optically Active cis- and trans-1-Amino-2-hydroxycyclohexane-1-carboxylic Acids

T. Shinada, H. Sakai, K. Namba, 2006 .

Stereocontrolled synthesis of a potent agonist of group II metabotropic glutamate receptors, (+)-LY354740, and its related derivatives

T. Shinada, S. Iwama, K. Shimamoto, 2003 .

Novel and efficient transformation of α-amino nitrile to α-imino and α-amide nitriles in asymmetric Strecker synthesis

T. Shinada, S. Iwama, M. Kawasaki, 2001 .

Total Synthesis and Absolute Structure of Manzacidin A and C

T. Shinada, K. Namba, Y. Ohfune, 2000 .

Synthesis of Allene-Containing Apocarotenoids by Cross-Coupling Strategy

S. Katsumura, T. Shinada, H. Hashimoto, 2020, Synthesis.

Stereocontrolled Synthesis of 19'-Deoxyperidinin.

S. Katsumura, T. Shinada, K. Sakaguchi, 2018, Organic letters.

Stereocontrolled Synthesis of Paracentrone

S. Katsumura, T. Shinada, K. Sakaguchi, 2016, Synlett.

Regioselective prins cyclization of allenylsilanes. Stereoselective formation of multisubstituted heterocyclic compounds.

T. Shinada, T. Okada, K. Sakaguchi, 2012, Organic letters.

Total synthesis of (-)-5,6,11-trideoxytetrodotoxin and its 4-epimer.

T. Shinada, H. Sakai, Y. Ohfune, 2006, Organic letters.

γ-C (sp3)-H bond functionalisation of α,β-unsaturated amides through an umpolung strategy.

T. Shinada, M. Yasui, O. Miyata, 2020, Organic & biomolecular chemistry.

Stereoselective Synthesis of Dehydroamino Acids and Its Application to the Synthesis of Nitrogen-containing Natural Products

T. Shinada, Y. Yasuno, Hironori Okamura, 2022, Journal of Synthetic Organic Chemistry, Japan.

The stereoselective construction of E- and Z-Δ-Ile from E-dehydroamino acid ester: the synthesis of the phomopsin A tripeptide side chain.

T. Shinada, Y. Ohfune, Y. Yasukawa, 2016, Chemical communications.

Stereoselective Synthesis of (E)‐α,β‐Dehydroamino Acid Esters

T. Shinada, Takeshi Yamada, Y. Ohfune, 2013 .

Catalytic Asymmetric Hydrogenation of Dehydroamino Acid Esters with Biscarbamate Protection and Its Application to the Synthesis of xCT Inhibitors.

T. Shinada, K. Shimamoto, Y. Yasuno, 2019, Chemistry.

Stereospecific nucleophilic addition reactions to olefins. Addition of thiols to .alpha.,.beta.-unsaturated carboxylic acid derivatives

T. Shinada, S. Inagaki, O. Miyata, 1991 .

Efficient asymmetric synthesis of the functionalized pyroglutamate core unit common to oxazolomycin and neooxazolomycin using Michael reaction of nucleophilic glycine Schiff base with α,β-disubstituted acrylate

T. Shinada, V. Soloshonok, Takeshi Yamada, 2008 .

Total Synthesis and Structure Elucidation of (.+-.)-Triumphalone and (.+-.)-Isotriumphalone.

T. Shinada, Y. Ohfune, E. Nishimura, 2015 .

Total Synthesis of a Monomeric Phloroglucinol Derivative Isolated from Myrtus communis

T. Shinada, Y. Ohfune, E. Nishimura, 2015 .

Formylation Reaction of Amines Using N-Formylcarbazole.

T. Shinada, T. Satoh, M. Kuse, 2022, Chemical & pharmaceutical bulletin.

Oxidation of hydrazones by hypervalent organoiodine reagents: Regeneration of the carbonyl group and facile syntheses of α-acetoxy and α-alkoxy azo compounds

T. Shinada, D. Barton, J. Jászberényi, 1996 .

Synthesis of optically active β-alkyl aspartate via [3,3] sigmatropic rearrangement of α-acyloxytrialkylsilane

T. Shinada, K. Shimamoto, Masahiro Yamamoto, 2004 .

Acid-catalyzed chirality-transferring intramolecular Friedel-Crafts cyclization of α-hydroxy-α-alkenylsilanes.

T. Shinada, K. Sakaguchi, Y. Ohfune, 2019, Chemical communications.

Structure Determination of a New Juvenile Hormone from a Heteropteran Insect

T. Kotaki, Kanako Kaihara, T. Shinada, 2009, Organic letters.

Stereoselective anti-SN2′ Mitsunobu reaction of α-hydroxy-α-alkenylsilanes

T. Shinada, K. Sakaguchi, Y. Ohfune, 2011 .

Total Synthesis of Manzacidins. An Overview and Perspective

T. Shinada, K. Namba, Y. Ohfune, 2012 .

Asymmetric Construction of Two Contiguous Stereocenters by Diastereoface Differentiating Addition Reaction of Thiols to Chiral Imides: Formal Synthesis of (+)‐Diltiazem.

T. Shinada, O. Miyata, T. Naito, 1997 .

Oxidation of phenylhydrazones of α-keto esters with hypervalent organoiodine reagents

T. Shinada, D. Barton, J. Jászberényi, 1993 .

Syntheses of Gabosine A, B, D, and E from Allyl Sulfide Derived from(-)-Quinic Acid

T. Shinada, Y. Ohfune, T. Fuji, 2002 .

Mechanisms of Sugar Aminotransferase-like Enzymes to Synthesize Stereoisomers of Non-proteinogenic Amino Acids in Natural Product Biosynthesis.

M. Nishiyama, T. Shinada, S. Kosono, 2023, ACS chemical biology.

Stereoselective Synthesis of (2 S ,6 R )‐Diamino‐(5 R ,7)‐dihydroxy‐heptanoic Acid (DADH): An Unusual Amino Acid from Streptomyces sp. SANK 60404

T. Shinada, H. Takikawa, Y. Yasuno, 2021 .

Stereoselective Syntheses of trans-Anhydromevalonic Acid and trans-Anhydromevalonyl Group-Containing Natural Products.

T. Shinada, Yuki Yamamoto, Y. Yasuno, 2022, Journal of natural products.

Reaction of cyclopropenes with a trichloromethyl radical: unprecedented ring-opening reaction of cyclopropanes with migration.

T. Shinada, O. Miyata, Masafumi Ueda, 2015, Chemical communications.

Efficient synthesis of optically active α-substituted glutamate analogs possessing α-hydroxymethyl and α-alkoxymethyl groups

T. Shinada, M. Kawasaki, K. Namba, 2003 .

Radical homologation of d-gluconic acid: highly diastereoselective synthesis of d-gluco-KDO derivatives

T. Shinada, D. Barton, M. L. Hyaric, 2001 .

The invention of radical reactions. Part XXXVI. Synthetic studies related to 3-deoxy-D-manno-2-octulosonic acid (KDO)

T. Shinada, D. Barton, J. Jászberényi, 1996 .

Total Synthesis and Structure Confirmation of trans-Anhydromevalonate-5-phosphate, a Key Biosynthetic Intermediate of the Archaeal Mevalonate Pathway.

H. Hemmi, T. Shinada, Y. Yasuno, 2021, Journal of natural products.

Toward the total synthesis of tetrodotoxin: stereoselective construction of the 7-oxanorbornane intermediate

T. Shinada, Y. Ohfune, A. Manabe, 2014 .

Preparation of E-α-stannyl-β-trimethylsilylethynylacrylate, building block for polyconjugated ylidenebutenolide and its derivatives, by novel E-selective ethynylstannylation of propiolate

S. Katsumura, T. Shinada, K. Sakaguchi, 2016 .

Solid phase synthesis of α-amino squaric acid-containing peptides

T. Shinada, Y. Kiniwa, Y. Ohfune, 2014 .

Using stable radicals to protect pentacene derivatives from photodegradation.

T. Shinada, Akihiro Shimizu, Y. Teki, 2013, Angewandte Chemie.

An unusual terpene cyclization mechanism involving a carbon-carbon bond rearrangement.

M. Nishiyama, Yumi Ando, T. Shinada, 2015, Angewandte Chemie.

“Cation-Stitching Cascade”: exquisite control of terpene cyclization in cyclooctatin biosynthesis

M. Nishiyama, T. Shinada, T. Kuzuyama, 2015, Scientific Reports.

Structure Determination of Juvenile Hormone from Chagas Disease Vectors,Rhodnius prolixusandTriatoma infestans

Keiji Matsumoto, T. Shinada, S. Goto, 2020 .

Stereoselective synthesis of 9-trans-9-Desmethyl-9-fluororetinals based on the four-components coupling approach

T. Shinada, N. Bojkova, K. Yoshihara, 1999 .

Spectroscopic Investigation of the Carotenoid Deoxyperidinin: Direct Observation of the Forbidden S0 → S1 Transition.

Jordan A. Greco, R. Birge, D. Niedzwiedzki, 2016, The journal of physical chemistry. B.

(7S)-Kaitocephalin as a potent NMDA receptor selective ligand.

T. Shinada, Y. Shigeri, K. Shimamoto, 2016, Organic & biomolecular chemistry.

Efficient total synthesis of (-)-kaitocephalin.

T. Shinada, Y. Ohfune, Makoto Hamada, 2009, Organic letters.

Structure-activity relationship study at C9 position of kaitocephalin.

T. Shinada, Y. Shigeri, K. Shimamoto, 2016, Bioorganic & medicinal chemistry letters.

The Structure of (−)-Kaitocephalin Bound to the Ligand Binding Domain of the (S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA)/Glutamate Receptor, GluA2*

R. Oswald, T. Shinada, Y. Ohfune, 2012, The Journal of Biological Chemistry.

Synthesis and paralytic activities of squaryl amino acid-containing polyamine toxins

T. Shinada, T. Nakajima, G. Corzo, 2003, Amino Acids.

Chain-elongation and degradation of carboxylic acids by barton-ester based radical chemistry

T. Shinada, D. Barton, C. Chern, 1993 .

A New Entry for the Synthesis of N-Acyl-N′-Substituted Guanidines.

T. Shinada, Y. Ohfune, T. Ando, 2006 .

First Synthesis of All-trans-polyprenol with 100 Carbons

T. Shinada, Y. Yasuno, Yusuke Totsuka, 2019, Chemistry Letters.

Biosynthesis of Sesterterpenes, Head‐to‐Tail Triterpenes, and Sesquarterpenes in Bacillus clausii: Identification of Multifunctional Enzymes and Analysis of Isoprenoid Metabolites

T. Shinada, Tsutomu Sato, Daijiro Ueda, 2015, Chembiochem : a European journal of chemical biology.

Identification of Novel Sesterterpene/Triterpene Synthase from Bacillus clausii

Y. Murata, T. Shinada, Chiaki Nakano, 2013, ChemBioChem.

Stereoselective isomerization of ethylidene lactam for the synthesis of (±)-Z-isositsirikines

T. Shinada, O. Miyata, T. Naito, 1989 .

Molecular Basis for Sesterterpene Diversity Produced by Plant Terpene Synthases

I. Abe, Guodong Wang, Jianxu Li, 2020, Plant communications.

Novel mastoparan and protonectin analogs isolated from a solitary wasp, Orancistrocerus drewseni drewseni

T. Shinada, H. Naoki, T. Nakajima, 2009, Amino Acids.

P-107 TOTAL SYNTHESIS OF 5,6,11-TRIDEOXYTETRODOTOXIN

T. Shinada, H. Sakai, Y. Ohfune, 2006 .

Mass spectrometric analysis of peptides in brain neurosecretory cells and neurohemal organs in the adult blowfly, Protophormia terraenovae.

T. Shinada, H. Numata, S. Shiga, 2010, Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.

Isolation of biologically active peptides from the venom of Japanese carpenter bee, Xylocopa appendiculata

T. Shinada, S. Goto, H. Kawakami, 2017, Journal of Venomous Animals and Toxins including Tropical Diseases.

Juvenile hormone III skipped bisepoxide is widespread in true bugs (Hemiptera: Heteroptera)

Keiji Matsumoto, T. Kotaki, T. Shinada, 2021, Royal Society Open Science.

Juvenile hormone identification in the cabbage bug Eurydema rugosa.

T. Shinada, S. Goto, Aya Kodama, 2023, Bulletin of entomological research.

Juvenile hormone III skipped bisepoxide, not its stereoisomers, as a juvenile hormone of the bean bug Riptortus pedestris.

Keiji Matsumoto, T. Kotaki, Yumi Ando, 2020, General and comparative endocrinology.

Structure Determination of a Natural Juvenile Hormone Isolated from a Heteropteran Insect

T. Kotaki, T. Shinada, H. Numata, 2012 .

Biological activities of juvenile hormone III skipped bisepoxide in last instar nymphs and adults of a stink bug, Plautia stali.

T. Kotaki, Kanako Kaihara, T. Shinada, 2011, Journal of insect physiology.

Juvenile hormone as a causal factor for maternal regulation of diapause in a wasp.

T. Shinada, S. Goto, Ayumu Mukai, 2022, Insect biochemistry and molecular biology.

Upregulation of Juvenile Hormone Titers in Female Drosophila melanogaster Through Mating Experiences and Host Food Occupied by Eggs and Larvae

Yasuhiro Sugime, T. Miura, N. K. Tanaka, 2017, Zoological Science.

A stereoisomer of JHSB3 with 10S-configuration, 10S-JHSB3, biosynthesized by the corpus allatum of the brown marmorated stink bug, Halyomorpha halys (Hemiptera: Pentatomidae)

Keiji Matsumoto, T. Kotaki, Kanako Kaihara, 2020, Applied Entomology and Zoology.

Ovicidal activity of juvenile hormone mimics in the bean bug, Riptortus pedestris

A. Jouraku, T. Shinada, Takao Nakagawa, 2021, Journal of pesticide science.

Facile synthesis of 6-hydroxyindole-3-acetic acid: On the structure of the aromatic subunit of nephilatoxin-1∼6

T. Shinada, H. Naoki, T. Nakajima, 1996 .

Facile Synthesis of 6‐Hydroxyindole‐3‐acetic Acid: On the Structure of the Aromatic Subunit of Nephilatoxin‐1‐6.

T. Shinada, H. Naoki, T. Nakajima, 1997 .

Synthesis of Fluorine Analogues of Protoporphyrin

T. Shinada, T. Nagai, A. Ando, 1989 .

Improved total synthesis of (±)-Tetragocarbone A

T. Shinada, Y. Yasuno, E. Nishimura, 2018 .

Xanthine oxidase inhibitory activities and crystal structures of methoxyflavones from Kaempferia parviflora rhizome.

T. Shinada, Y. Ohfune, H. Matsuda, 2011, Biological & pharmaceutical bulletin.

A novel cyclic peptide (Naturido) modulates glia–neuron interactions in vitro and reverses ageing-related deficits in senescence-accelerated mice

T. Shinada, H. Harada, K. Otsu, 2021, PloS one.

Reagent-controlled regiodivergence in the [3,3]-sigmatropic rearrangement of N-(acyloxy)enamides

T. Shinada, O. Miyata, Masafumi Ueda, 2019, Organic Chemistry Frontiers.

Cyclolavandulyl skeleton biosynthesis via both condensation and cyclization catalyzed by an unprecedented member of the cis-isoprenyl diphosphate synthase superfamily.

M. Nishiyama, T. Shinada, T. Kuzuyama, 2014, Journal of the American Chemical Society.

Facile Synthesis of Deuterium-Labelled Geranylgeraniols

T. Shinada, T. Kuzuyama, Shota Ueda, 2015 .

Chiral isoxazolidine-mediated stereoselective umpolung α-phenylation of methyl ketones.

T. Shinada, O. Miyata, Masafumi Ueda, 2018, Organic & biomolecular chemistry.

A quinone isolated from the nest of Vespa simillima and its growth-inhibitory effect on rat liver cancer cells.

T. Shinada, Y. Ohfune, H. Kofujita, 2008, Biological & pharmaceutical bulletin.

Synthesais of Corynanthe Alkaloids Corynantheine, Hirsuteine, and the Isositsirkines

T. Shinada, T. Ishida, O. Miyata, 1990 .

Short and stereoselective synthesis of manzacidins A and C, and their enantiomers

T. Shinada, Y. Ohfune, K. Oe, 2008 .

Synthesis and absolute structure of manzacidin B.

T. Shinada, M. Kawasaki, K. Namba, 2007, Organic letters.

Reconstitution of a Highly Reducing Type II PKS System Reveals 6π-Electrocyclization Is Required for o-Dialkylbenzene Biosynthesis.

M. Nishiyama, T. Shinada, T. Kuzuyama, 2021, Journal of the American Chemical Society.

A [4Fe-4S] cluster resides at the active center of phosphomevalonate dehydratase, a key enzyme in the archaeal modified mevalonate pathway

H. Hemmi, T. Shinada, Tomokazu Ito, 2023, Frontiers in Microbiology.

Stereoselective Total Syntheses of Insect Juvenile Hormones JH 0 and JH I

T. Shinada, Y. Ohfune, A. Manabe, 2012 .

Efficient Synthesis of EDO-S,S-DMEDT-TTF, a Potent Organic-Donor for Synthetic Metals

T. Shinada, G. Papavassiliou, K. Murata, 2001 .

Conserved gatekeeper methionine regulates the binding and access of kinase inhibitors to ATP sites of MAP2K1, 4, and 7: Clues for developing selective inhibitors.

Daisuke Kitagawa, T. Shinada, Takayoshi Kinoshita, 2024, Bioorganic & medicinal chemistry letters.