I. Rapa

发表

mTOR pathway activation in multiple myeloma cell lines and primary tumour cells: pomalidomide enhances cytoplasmic-nuclear shuttling of mTOR protein

M. Papotti, G. Saglio, T. Guglielmelli, 2015, Oncoscience.

Human ASH1 expression in prostate cancer with neuroendocrine differentiation

Francesco Porpiglia, Enrico Bollito, Mauro Papotti, 2008, Modern Pathology.

Micro-RNA-215 and -375 regulate thymidylate synthase protein expression in pleural mesothelioma and mediate epithelial to mesenchymal transition

G. Scagliotti, M. Papotti, R. Taulli, 2022, Virchows Archiv.

Soluble CD157 in pleural effusions: a complementary tool for the diagnosis of malignant mesothelioma

S. Novello, I. Rapa, M. Volante, 2018, Oncotarget.

CD157 enhances malignant pleural mesothelioma aggressiveness and predicts poor clinical outcome

G. Scagliotti, S. Novello, S. Orecchia, 2014, Oncotarget.

Thymidylate synthase drives the phenotypes of epithelial-to-mesenchymal transition in non-small cell lung cancer

I. Asangani, M. A. Siddiqui, P. Ceppi, 2020, British journal of cancer.

Obestatin in human neuroendocrine tissues and tumours: expression and effect on tumour growth

M. Papotti, P. Cassoni, B. Wiedenmann, 2009, The Journal of pathology.

Androgen deprivation modulates gene expression profile along prostate cancer progression.

M. Papotti, I. Rapa, J. Giorcelli, 2016, Human pathology.

High interlaboratory and interobserver agreement of somatostatin receptor immunohistochemical determination and correlation with response to somatostatin analogs.

W. Ito, M. Papotti, H. Sasano, 2018, Human pathology.

Activity and safety of temozolomide in advanced adrenocortical carcinoma patients.

A. Russo, I. Rapa, S. Grisanti, 2019, European journal of endocrinology.

MicroRNA profiling predicts positive nodal status in papillary thyroid carcinoma in the preoperative setting

M. Papotti, G. Troncone, C. Bellevicine, 2022, Cancer cytopathology.

Impact of pregnancy on prognosis of differentiated thyroid cancer: clinical and molecular features.

I. Rapa, J. Giorcelli, M. Volante, 2014, European journal of endocrinology.

MicroRNA expression patterns in adrenocortical carcinoma variants and clinical pathologic correlations.

G. Scagliotti, M. Papotti, I. Rapa, 2014, Human pathology.

Achaete-scute homolog 1 as a marker of poorly differentiated neuroendocrine carcinomas of different sites: a validation study using immunohistochemistry and quantitative real-time polymerase chain reaction on 335 cases.

M. Papotti, I. Rapa, F. Sessa, 2013, Human pathology.

Thymidylate synthase drives the phenotypes of epithelial-to-mesenchymal transition in non-small cell lung cancer

I. Asangani, M. A. Siddiqui, P. Ceppi, 2020, bioRxiv.

Thymidylate Synthase Expression in Gastroenteropancreatic and Pulmonary Neuroendocrine Tumors

G. Scagliotti, M. Papotti, P. Ceppi, 2008, Clinical Cancer Research.

Molecular Subtypes of Extra-pulmonary Neuroendocrine Carcinomas Identified by the Expression of Neuroendocrine Lineage-Specific Transcription Factors

G. Scagliotti, M. Papotti, I. Rapa, 2022, Endocrine pathology.

IMPACT OF PREGNANCY ON PROGNOSIS OF DIFFERENTIATED 13 THYROID CANCER : CLINICAL AND MOLECULAR FEATURES 14 15

I. Rapa, J. Giorcelli, M. Volante, 2014 .

High miR-100 expression is associated with aggressive features and modulates TORC1 complex activation in lung carcinoids

G. Scagliotti, M. Papotti, A. Scarpa, 2018, Oncotarget.

Targeting the multidrug transporter Patched potentiates chemotherapy efficiency on adrenocortical carcinoma in vitro and in vivo

F. Beuschlein, E. Lalli, I. Rapa, 2018, International journal of cancer.

THYROID CANCER: CLINICAL AND MOLECULAR FEATURES

I. Rapa, J. Giorcelli, M. Volante, 2014 .

Poorly Differentiated Thyroid Carcinoma: Diagnostic Features and Controversial Issues

M. Papotti, I. Rapa, M. Volante, 2008, Endocrine pathology.

Differential ligand-mediated pituitary somatostatin receptor subtype signaling: implications for corticotroph tumor therapy.

M. Papotti, Y. Nikiforov, S. Melmed, 2009, The Journal of clinical endocrinology and metabolism.

Poorly Differentiated Carcinoma of the Thyroid Gland

M. Papotti, I. Rapa, M. Volante, 2009 .

Micro-RNA-215 and -375 regulate thymidylate synthase protein expression in pleural mesothelioma and mediate epithelial to mesenchymal transition

G. Scagliotti, M. Papotti, R. Taulli, 2022, Virchows Archiv.

Tumor/stromal caveolin-1 expression patterns in pleural mesothelioma define a subgroup of the epithelial histotype with poorer prognosis.

G. Scagliotti, M. Papotti, I. Rapa, 2014, American journal of clinical pathology.

Mammalian target of rapamycin pathway activation is associated to RET mutation status in medullary thyroid carcinoma.

M. Papotti, I. Rapa, D. Giachino, 2011, The Journal of clinical endocrinology and metabolism.

MAMMALIAN TARGET OF RAPAMYCIN ( mTOR ) SIGNALLING ACTIVATION 1 PATTERNS IN NEUROENDOCRINE TUMORS OF THE LUNG 2 3

G. Pelosi, M. Papotti, I. Rapa, 2014 .

Functional role and prognostic significance of CD157 in ovarian carcinoma.

D. Katsaros, G. Migliaretti, I. Rapa, 2010, Journal of the National Cancer Institute.

Human ASH‐1 Promotes Neuroendocrine Differentiation in Androgen Deprivation Conditions and Interferes With Androgen Responsiveness in Prostate Cancer Cells

M. Papotti, S. Giordano, I. Rapa, 2013, The Prostate.

CYP11B1 has no role in mitotane action and metabolism in adrenocortical carcinoma cells

I. Rapa, L. Saba, M. Volante, 2018, PloS one.

Topoisomerase 2α and thymidylate synthase expression in adrenocortical cancer.

G. Scagliotti, M. Papotti, L. Ferrari, 2017, Endocrine-related cancer.

Prognostic and predictive role of topoisomerase alpha 2 and thymidylate synthase expression in tumor tissues of patients with adrenocortical carcinoma

G. Scagliotti, M. Papotti, M. Fassnacht, 2017 .

Ribonucleotide Reductase Large Subunit (RRM1) Gene Expression May Predict Efficacy of Adjuvant Mitotane in Adrenocortical Cancer

G. Scagliotti, M. Papotti, M. Fassnacht, 2012, Clinical Cancer Research.

1 Cytotoxic activity of gemcitabine , alone or in combination with mitotane , in adrenocortical carcinoma cell lines

Alfredo, M. Papotti, I. Rapa, 2022 .

Cytotoxic activity of gemcitabine, alone or in combination with mitotane, in adrenocortical carcinoma cell lines

M. Papotti, I. Rapa, M. Volante, 2014, Molecular and Cellular Endocrinology.

Micro-RNA-215 and -375 regulate thymidylate synthase protein expression in pleural mesothelioma and mediate epithelial to mesenchymal transition

G. Scagliotti, M. Papotti, R. Taulli, 2022, Virchows Archiv.

ACTH-producing tumorlets and carcinoids of the lung: clinico-pathologic study of 63 cases and review of the literature

M. Papotti, P. Granone, I. Rapa, 2019, Virchows Archiv.

Molecular Subtypes of Extra-pulmonary Neuroendocrine Carcinomas Identified by the Expression of Neuroendocrine Lineage-Specific Transcription Factors

G. Scagliotti, M. Papotti, I. Rapa, 2022, Endocrine Pathology.

The mTORC1 Complex Is Significantly Overactivated in SDHX-Mutated Paragangliomas

M. Smid, M. Papotti, E. Korpershoek, 2017, Neuroendocrinology.

Differential Expression Profiles of Cell-to-Matrix-Related Molecules in Adrenal Cortical Tumors: Diagnostic and Prognostic Implications

M. Papotti, I. Rapa, M. Volante, 2021, Journal of personalized medicine.

Tissue Expression and Pharmacological In Vitro Analyses of mTOR and SSTR Pathways in Adrenocortical Carcinoma

G. Scagliotti, M. Papotti, I. Rapa, 2017, Endocrine Pathology.

EFFECTS OF COMBINED EVEROLIMUS AND PASIREOTIDE WITH MITOTANE TREATMENT IN ADRENOCORTICAL CARCINOMA CELL LINES

G. Scagliotti, M. Papotti, I. Rapa, 2022 .

Proposal of a Panel of Genes Identified by miRNA Profiling as Candidate Prognostic Biomarkers in Lung Carcinoids

I. Rapa, J. Giorcelli, M. Volante, 2020, Neuroendocrinology.

Multiple Assays to Determine Methylguanine-Methyltransferase Status in Lung Carcinoids and Correlation with Clinical and Pathological Features

G. Scagliotti, M. Papotti, I. Rapa, 2019, Neuroendocrinology.

Predictive molecular pathology in the time of coronavirus disease (COVID-19) in Europe

G. Fontanini, M. Fassan, B. Weynand, 2020, Journal of Clinical Pathology.

Dissecting Morphological and Molecular Heterogeneity in Adrenocortical Carcinoma.

M. Papotti, I. Rapa, M. Volante, 2015, Turk patoloji dergisi.

Somatostatin Receptors in Malignancies and Other Pathologies

M. Papotti, A. Cassenti, I. Rapa, 2015 .

Functional r ole and Prognostic Significance of c D157 in Ovarian c arcinoma

D. Katsaros, G. Migliaretti, I. Rapa, 2010 .

Somatostatin receptor type 2A immunohistochemistry in neuroendocrine tumors: a proposal of scoring system correlated with somatostatin receptor scintigraphy

M. Papotti, A. Colao, A. Faggiano, 2007, Modern Pathology.

Loss of miR-200c Expression Induces an Aggressive, Invasive, and Chemoresistant Phenotype in Non–Small Cell Lung Cancer

H. Allgayer, G. Scagliotti, M. Papotti, 2010, Molecular Cancer Research.

Personalized therapeutic strategies in HER2-driven gastric cancer

A. Sapino, S. Bellomo, P. Cassoni, 2021, Gastric Cancer.

Retrospective study testing next generation sequencing of selected cancer-associated genes in resected prostate cancer

G. Scagliotti, M. Papotti, I. Rapa, 2016, Oncotarget.

Detailed genomic characterization identifies high heterogeneity and histotype-specific genomic profiles in adrenocortical carcinomas

G. Scagliotti, I. Rapa, J. Giorcelli, 2018, Modern Pathology.

Proton pump inhibitors promote the growth of androgen-sensitive prostate cancer cells through ErbB2, ERK1/2, PI3K/Akt, GSK-3β signaling and inhibition of cellular prostatic acid phosphatase.

M. Papotti, E. Ghigo, I. Rapa, 2019, Cancer letters.

Polyol Pathway Links Glucose Metabolism to the Aggressiveness of Cancer Cells.

P. Oefner, S. A. K. Rasheed, A. Ekici, 2018, Cancer research.

Neuro-endocrine tumours of the lung. A review of relevant pathological and molecular data

G. Scagliotti, M. Papotti, I. Rapa, 2007, Virchows Archiv.

Molecular and Histological Changes in Post-Treatment Biopsies of Non-Squamous Non-Small Cell Lung Cancer: A Retrospective Study

G. Scagliotti, M. Papotti, S. Novello, 2016, Targeted Oncology.

CD 157 enhances malignant pleural mesothelioma aggressiveness and predicts poor clinical outcome

G. Scagliotti, S. Novello, S. Orecchia, 2014 .

ERCC1 and RRM1 gene expressions but not EGFR are predictive of shorter survival in advanced non-small-cell lung cancer treated with cisplatin and gemcitabine.

M Volante, G. Scagliotti, M. Papotti, 2006, Annals of oncology : official journal of the European Society for Medical Oncology.

Thymidylate synthase is functionally associated with ZEB1 and contributes to the epithelial‐to‐mesenchymal transition of cancer cells

P. Ceppi, I. Rapa, T. Brabletz, 2017, The Journal of pathology.

Mammalian target of rapamycin signaling activation patterns in neuroendocrine tumors of the lung.

G. Pelosi, M. Papotti, I. Rapa, 2010, Endocrine-related cancer.

Mechanical phenotyping of cells and extracellular matrix as grade and stage markers of lung tumor tissues.

P. Netti, S. Fusco, I. Rapa, 2017, Acta biomaterialia.

Squamous cell carcinoma of the lung compared with other histotypes shows higher messenger RNA and protein levels for thymidylate synthase

G. Scagliotti, M. Papotti, S. Novello, 2006, Cancer.

Human achaete-scute homolog-1 expression in neuroendocrine breast carcinoma

M. Papotti, A. Sapino, I. Rapa, 2012, Virchows Archiv.

H-RAS mutations are restricted to sporadic pheochromocytomas lacking specific clinical or pathological features: data from a multi-institutional series.

M. Papotti, E. Korpershoek, F. Beuschlein, 2014, The Journal of clinical endocrinology and metabolism.

Images in Endocrine Pathology: Unique Composite Adrenal Adenomatoid Tumor, Ganglioneuroma, Myelolipoma, and Cortical Nodular Hyperplasia

M. Papotti, S. Guzzetti, I. Rapa, 2017, Endocrine Pathology.

Therapeutic Biomarkers in Lung Neuroendocrine Neoplasia

G. Pelosi, M. Papotti, I. Rapa, 2014, Endocrine Pathology.

Expression and pharmacological inhibition of thymidylate synthase and Src kinase in nonsmall cell lung cancer

G. Scagliotti, M. Papotti, P. Ceppi, 2012, International journal of cancer.

Absence of RET gene point mutations in sporadic thyroid C-cell hyperplasia.

M. Papotti, I. Rapa, G. Bussolati, 2007, The Journal of molecular diagnostics : JMD.

chemoresistant phenotype in non-small cell lung cancer.

H. Allgayer, M. Papotti, P. Ceppi, 2010 .

The oncocytic variant of poorly differentiated thyroid carcinoma shows a specific immune-related gene expression profile.

M. Papotti, Y. Nikiforov, I. Rapa, 2020, The Journal of clinical endocrinology and metabolism.

Cathepsin K is selectively expressed in the stroma of lung adenocarcinoma but not in bronchioloalveolar carcinoma. A useful marker of invasive growth.

G. Scagliotti, M. Papotti, I. Rapa, 2006, American journal of clinical pathology.

Cathepsin K Is Selectively Expressed in the Stroma of Lung Adenocarcinoma but Not in Bronchioloalveolar Carcinoma

G. Scagliotti, M. Papotti, I. Rapa, 2005 .

Identification of MicroRNAs Differentially Expressed in Lung Carcinoid Subtypes and Progression

G. Scagliotti, M. Papotti, A. Scarpa, 2015, Neuroendocrinology.

Molecular Cancer esearch cer Genes and Genomics s of miR-200 c Expression Induces an Aggressive , sive , and Chemoresistant Phenotype in R – Small Cell Lung Cancer

H. Allgayer, G. Scagliotti, I. Rapa, 2010 .

Epidermal growth factor ligand/receptor loop and downstream signaling activation pattern in completely resected nonsmall cell lung cancer

G. Scagliotti, M. Papotti, S. Novello, 2007, Cancer.

RRM1 modulates mitotane activity in adrenal cancer cells interfering with its metabolization

M. Papotti, I. Rapa, M. Volante, 2015, Molecular and Cellular Endocrinology.

Primary lung adenocarcinoma in three adolescent patients affected by bone sarcomas

M. Papotti, A. D. Dei Tos, I. Rapa, 2021, Virchows Archiv.

micro-RNA EXPRESSION PATTERNS IN ADRENOCORTICAL CARCINOMA VARIANTS AND CLINICAL PATHOLOGICAL CORRELATIONS

G. Scagliotti, M. Papotti, I. Rapa, 2022 .

Treatment with 90Y/177Lu DOTATOC in patients with metastatic adrenocortical carcinoma expressing somatostatin receptors.

G. Tiberio, I. Rapa, A. Versari, 2020, The Journal of clinical endocrinology and metabolism.

Impact of Non–Small-Cell Lung Cancer-Not Otherwise Specified Immunophenotyping on Treatment Outcome

Giulio Rossi, Mauro Papotti, Simona Vatrano, 2014, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

ERCC1 and RRM1 gene expressions but not EGFR are predictive of shorter survival in advanced non-small-cell lung cancer treated with cisplatin and gemcitabine.

G. Scagliotti, M. Papotti, S. Novello, 2006, Annals of oncology : official journal of the European Society for Medical Oncology.

Real-world EGFR testing practices for non-small-cell lung cancer by thoracic pathology laboratories across Europe.

D. Kazdal, N. Normanno, A. Rappa, 2023, ESMO open.

Cytotoxic activity of gemcitabine, alone or in combination with mitotane, in adrenocortical carcinoma cell lines

M. Papotti, I. Rapa, M. Volante, 2014, Molecular and Cellular Endocrinology.

Topoisomerase 2α and thymidylate synthase expression in adrenocortical cancer.

G. Scagliotti, M. Papotti, L. Ferrari, 2017, Endocrine-related cancer.

Ribonucleotide Reductase Large Subunit (RRM1) Gene Expression May Predict Efficacy of Adjuvant Mitotane in Adrenocortical Cancer

G. Scagliotti, M. Papotti, M. Fassnacht, 2012, Clinical Cancer Research.

ACTH-producing tumorlets and carcinoids of the lung: clinico-pathologic study of 63 cases and review of the literature

M. Papotti, P. Granone, I. Rapa, 2019, Virchows Archiv.