C. Oneyama

发表

mLST8 Promotes mTOR-Mediated Tumor Progression

E. Morii, M. Okada, K. Kakumoto, 2015, PloS one.

MicroRNA-mediated downregulation of mTOR/FGFR3 controls tumor growth induced by Src-related oncogenic pathways

E. Morii, M. Okada, J. Ikeda, 2011, Oncogene.

FRA1 is a determinant for the difference in RAS-induced transformation between human and rat fibroblasts.

H. Hanafusa, E. Mekada, T. Sukezane, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Functional dissection of transformation by c‐Src and v‐Src

S. Nada, M. Okada, C. Oneyama, 2007, Genes to cells : devoted to molecular & cellular mechanisms.

Purvalanol A, a CDK inhibitor, effectively suppresses Src‐mediated transformation by inhibiting both CDKs and c‐Src

M. Okada, C. Oneyama, T. Hikita, 2010, Genes to cells : devoted to molecular & cellular mechanisms.

Asteltoxin inhibits extracellular vesicle production through AMPK/mTOR-mediated activation of lysosome function

A. Setiawan, C. Oneyama, T. Hikita, 2022, Scientific Reports.

A mass spectrometric method for in-depth profiling of phosphoinositide regioisomers and their disease-associated regulation

H. Nakanishi, A. Suzuki, Takehiko Sasaki, 2022, Nature communications.

Exosomes secreted from cancer-associated fibroblasts elicit anti-pyrimidine drug resistance through modulation of its transporter in malignant lymphoma

M. Sanada, C. Oneyama, T. Aoki, 2021, Oncogene.

UCS15A, a non-kinase inhibitor of Src signal transduction

Sreenath V. Sharma, T. Tamaoki, H. Nakano, 2001, Oncogene.

Roles of Raft-Anchored Adaptor Cbp/PAG1 in Spatial Regulation of c-Src Kinase

M. Okada, C. Oneyama, K. Kajiwara, 2014, PloS one.

Involvement of gangliosides in the process of Cbp/PAG phosphorylation by Lyn in developing cerebellar growth cones

M. Okada, C. Oneyama, Hidenori Suzuki, 2013, Journal of neurochemistry.

The Transmembrane Adaptor Cbp/PAG1 Controls the Malignant Potential of Human Non–Small Cell Lung Cancers That Have c-Src Upregulation

M. Okada, M. Ohta, C. Oneyama, 2010, Molecular Cancer Research.

Sensitive and rapid quantification of exosomes by fusing luciferase to exosome marker proteins

C. Oneyama, T. Hikita, Mamiko Miyata, 2018, Scientific Reports.

Transforming Potential of Src Family Kinases Is Limited by the Cholesterol-Enriched Membrane Microdomain

A. Ogawa, M. Okada, C. Oneyama, 2009, Molecular and Cellular Biology.

ROR1 sustains multivesicular endosomes by interacting with HRS and STAM1

C. Oneyama, Tomoya Yamaguchi, Masatoshi Yamamoto, 2020 .

SNAP23-Mediated Perturbation of Cholesterol-Enriched Membrane Microdomain Promotes Extracellular Vesicle Production in Src-Activated Cancer Cells.

A. Hirayama, C. Oneyama, Ryosuke Hayasaka, 2022, Biological & pharmaceutical bulletin.

Identification of a New Interaction Mode between the Src Homology 2 Domain of C-terminal Src Kinase (Csk) and Csk-binding Protein/Phosphoprotein Associated with Glycosphingolipid Microdomains♦

T. Ikegami, A. Nakagawa, M. Okada, 2013, The Journal of Biological Chemistry.

Targeting AMAP 1 and cortactin binding bearing an atypical src homology 3 proline interface for prevention of breast cancer invasion and metastasis

H. Hosaka, T. Ikegami, H. Wada, 2006 .

Exendin-4 suppresses Src activation and reactive oxygen species production in diabetic GK rat islets in an Epac-dependent manner

Hiroki Sato, M. Okada, C. Oneyama, 2010 .

Signaling and Regulation The Transmembrane Adaptor Cbp / PAG 1 Controls the Malignant Potential of Human Non – Small Cell Lung Cancers That Have cSrc Upregulation

M. Okada, M. Ohta, C. Oneyama, 2011 .

Efficient Epstein-Barr Virus Progeny Production Mediated by Cancer-Derived LMP1 and Virally-Encoded microRNAs

T. Kanda, C. Oneyama, Y. Hasegawa, 2019, Microorganisms.

Constitutive phosphorylation of a Rac GAP MgcRacGAP is implicated in v‐Src‐induced transformation of NIH3T3 cells

T. Kitamura, T. Akagi, C. Oneyama, 2009, Cancer science.

Metabolomics of small extracellular vesicles derived from isocitrate dehydrogenase 1-mutant HCT116 cells collected by semi-automated size exclusion chromatography

Y. Baba, T. Soga, A. Hirayama, 2023, Frontiers in Molecular Biosciences.

The activation of SRC family kinases and focal adhesion kinase with the loss of the amplified, mutated EGFR gene contributes to the resistance to afatinib, erlotinib and osimertinib in human lung cancer cells

K. Nishio, M. Kuwano, M. Ono, 2017, Oncotarget.

The guanine nucleotide exchange factor Arhgef5 plays crucial roles in Src-induced podosome formation

S. Nada, M. Okada, C. Oneyama, 2011, Journal of Cell Science.

A mass spectrometric method for in-depth profiling of phosphoinositide regioisomers and their disease-associated regulation

Takehiko Sasaki, Toshiyoshi Yamamoto, C. Oneyama, 2022, Nature Communications.

MicroRNA‐27b suppresses tumor progression by regulating ARFGEF1 and focal adhesion signaling

M. Okada, C. Oneyama, D. Okuzaki, 2015, Cancer science.

MiR-424/503-Mediated Rictor Upregulation Promotes Tumor Progression

K. Takayama, S. Inoue, E. Morii, 2013, PloS one.

Autonomous regulation of osteosarcoma cell invasiveness by Wnt5a/Ror2 signaling

T. Takumi, Y. Minami, M. Okada, 2009, Oncogene.

MicroRNAs as the fine-tuners of Src oncogenic signalling.

M. Okada, C. Oneyama, Chitose Oneyama, 2015, Journal of biochemistry.

MEK/ERK‐mediated oncogenic signals promote secretion of extracellular vesicles by controlling lysosome function

C. Oneyama, T. Hikita, Takuya Yoshida, 2022, Cancer science.

Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis.

H. Hosaka, T. Ikegami, H. Wada, 2006, Proceedings of the National Academy of Sciences of the United States of America.

MicroRNA-mediated upregulation of integrin-linked kinase promotes Src-induced tumor progression

E. Morii, M. Okada, J. Ikeda, 2012, Oncogene.

Oncogenic mutation or overexpression of oncogenic KRAS or BRAF is not sufficient to confer oncogene addiction

K. Aoki, C. Oneyama, Reina E. Ito, 2020, bioRxiv.

Filopodium-derived vesicles produced by MIM enhance the migration of recipient cells.

K. Ikeda, Y. Takai, C. Oneyama, 2021, Developmental cell.

UCS15A, a novel small molecule, SH3 domain-mediated protein–protein interaction blocking drug

Sreenath V. Sharma, H. Nakano, C. Oneyama, 2002, Oncogene.

Synthetic inhibitors of proline-rich ligand-mediated protein-protein interaction: potent analogs of UCS15A.

Sreenath V. Sharma, H. Nakano, C. Oneyama, 2003, Chemistry & biology.

The mTOR Pathway Controls Cell Proliferation by Regulating the FoxO3a Transcription Factor via SGK1 Kinase

S. Nada, M. Okada, C. Oneyama, 2014, PloS one.

P53- and mevalonate pathway–driven malignancies require Arf6 for metastasis and drug resistance

Y. Onodera, M. Okada, C. Oneyama, 2016, The Journal of cell biology.

Functional development of Src tyrosine kinases during evolution from a unicellular ancestor to multicellular animals

T. Miyata, M. Okada, T. Akagi, 2006, Proceedings of the National Academy of Sciences.

Purification and characterization of a non-S-RNase and S-RNases from styles of Japanese pear (Pyrus pyrifolia).

C. Oneyama, T. Shinkawa, S. Norioka, 2007, Plant physiology and biochemistry : PPB.

The Rho guanine nucleotide exchange factor ARHGEF5 promotes tumor malignancy via epithelial–mesenchymal transition

Y. Onodera, Y. Komiya, S. Nada, 2016, Oncogenesis.

C‐terminal Src kinase controls development and maintenance of mouse squamous epithelia

S. Nada, M. Okada, C. Oneyama, 2007, The EMBO journal.

c‐Src promotes tumor progression through downregulation of microRNA‐129‐1‐3p

C. Oneyama, D. Okuzaki, Y. Ninomiya, 2019, Cancer science.

MicroRNA‐137‐mediated Src oncogenic signaling promotes cancer progression

C. Oneyama, D. Okuzaki, Risayo Watanabe, 2018, Genes to cells : devoted to molecular & cellular mechanisms.

The lipid raft-anchored adaptor protein Cbp controls the oncogenic potential of c-Src.

A. Tarakhovsky, S. Nada, M. Okada, 2008, Molecular cell.

Structural insight into the specific interaction between murine SHPS-1/SIRP alpha and its ligand CD47.

A. Nakagawa, M. Okada, T. Matozaki, 2008, Journal of molecular biology.

Src in endosomal membranes promotes exosome secretion and tumor progression

A. Kuwahara, C. Oneyama, T. Hikita, 2019, Scientific Reports.

Fer tyrosine kinase oligomer mediates and amplifies Src-induced tumor progression

M. Okada, C. Oneyama, S. Tsukita, 2016, Oncogene.

c-Src-induced activation of ceramide metabolism impairs membrane microdomains and promotes malignant progression by facilitating the translocation of c-Src to focal adhesions.

E. Fukusaki, T. Bamba, M. Okada, 2014, The Biochemical journal.

Proteomic identification of ZO-1/2 as a novel scaffold for Src/Csk regulatory circuit.

M. Okada, C. Oneyama, T. Hikita, 2008, Biochemical and biophysical research communications.

Molecular cloning and nucleotide sequences of cDNAs encoding S-allele specific stylar RNases in a self-incompatible cultivar and its self-compatible mutant of Japanese pear, Pyrus pyrifolia Nakai.

C. Oneyama, N. Norioka, S. Norioka, 1996, Journal of biochemistry.

Down-regulation of the Tumor Suppressor C-terminal Src Kinase (Csk)-binding Protein (Cbp)/PAG1 Is Mediated by Epigenetic Histone Modifications via the Mitogen-activated Protein Kinase (MAPK)/Phosphatidylinositol 3-Kinase (PI3K) Pathway*

M. Okada, C. Oneyama, S. Tajima, 2011, The Journal of Biological Chemistry.

Ablation of Csk in neural crest lineages causes corneal anomaly by deregulating collagen fibril organization and cell motility.

S. Nada, M. Okada, C. Oneyama, 2008, Developmental biology.

Dissection of Wnt5a-Ror2 Signaling Leading to Matrix Metalloproteinase (MMP-13) Expression*

Y. Minami, M. Okada, C. Oneyama, 2011, The Journal of Biological Chemistry.

A versatile nonviral vector system for tetracycline-dependent one-step conditional induction of transgene expression

F. Imamoto, C. Oneyama, T. Sone, 2009, Gene Therapy.

Csk-binding Protein / Phosphoprotein C-terminal Src Kinase ( Csk ) and between the Src Homology 2 Domain of Identification of a New Interaction Mode Protein Structure and Folding :

T. Ikegami, A. Nakagawa, M. Okada, 2013 .

The lysosomal signaling anchor p18/LAMTOR1 controls epidermal development by regulating lysosome-mediated catabolic processes

S. Nada, M. Okada, C. Oneyama, 2013, Journal of Cell Science.

Drug-target identification from total cellular lysate by drug-induced conformational changes.

K. Yano, Sreenath V. Sharma, H. Nakano, 2009, Analytical biochemistry.

Src in endosomal membranes promotes exosome secretion and tumor progression

A. Kuwahara, C. Oneyama, T. Hikita, 2019, Scientific Reports.

Exendin-4 Suppresses Src Activation and Reactive Oxygen Species Production in Diabetic Goto-Kakizaki Rat Islets in an Epac-Dependent Manner

M. Okada, C. Oneyama, N. Inagaki, 2010, Diabetes.

Human diploid fibroblasts are resistant to MEK/ERK-mediated disruption of the actin cytoskeleton and invasiveness stimulated by Ras

H. Hanafusa, T. Sukezane, T. Akagi, 2005, Oncogene.

In vivo imaging of long-term accumulation of cancer-derived exosomes using a BRET-based reporter

C. Oneyama, T. Hikita, Mamiko Miyata, 2020, Scientific Reports.

Sensitive and rapid quantification of exosomes by fusing luciferase to exosome marker proteins

C. Oneyama, T. Hikita, Mamiko Miyata, 2018, Scientific Reports.

The late endosome/lysosome-anchored p18-mTORC1 pathway controls terminal maturation of lysosomes.

S. Nada, M. Okada, C. Oneyama, 2012, Biochemical and biophysical research communications.