Yiqiang Zhang

发表

Mice Fed Rapamycin Have an Increase in Lifespan Associated with Major Changes in the Liver Transcriptome

W. Wood, K. Becker, W. Fok, 2014, PloS one.

Loss of manganese superoxide dismutase leads to abnormal growth and signal transduction in mouse embryonic fibroblasts.

Hong-Mei Zhang, Yun Shi, Yiqiang Zhang, 2010, Free radical biology & medicine.

Rapamycin extends life and health in C57BL/6 mice.

S. Austad, W. Ward, A. Bokov, 2014, The journals of gerontology. Series A, Biological sciences and medical sciences.

Melatonin: a well‐documented antioxidant with conditional pro‐oxidant actions

Yiqiang Zhang, Hong-Mei Zhang, 2014, Journal of pineal research.

Molecular mechanisms of melatonin in the reversal of LPS-induced EMT in peritoneal mesothelial cells.

Lin Sun, Yiqiang Zhang, S. Shi, 2016, Molecular medicine reports.

Normal function of HERG K+ channels expressed in HEK293 cells requires basal protein kinase B activity

Hui-zhen Wang, S. Nattel, Yiqiang Zhang, 2003, FEBS letters.

CuZnSOD gene deletion targeted to skeletal muscle leads to loss of contractile force but does not cause muscle atrophy in adult mice

Yun Shi, M. Jackson, Yiqiang Zhang, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Neuron‐specific expression of CuZnSOD prevents the loss of muscle mass and function that occurs in homozygous CuZnSOD‐knockout mice

Yun Shi, M. Jackson, Yiqiang Zhang, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Sustained NFκB inhibition improves insulin sensitivity but is detrimental to muscle health

S. Austad, S. Shoelson, P. Osmulski, 2017, Aging cell.

The paradoxical role of thioredoxin on oxidative stress and aging.

Yiqiang Zhang, A. Salmon, J. Gelfond, 2015, Archives of biochemistry and biophysics.

Thioredoxin, oxidative stress, cancer and aging

Yiqiang Zhang, A. Salmon, Shuko Lee, 2012, Longevity & healthspan.

Progressive apoptotic cell death triggered by transient oxidative insult in H9c2 rat ventricular cells: a novel pattern of apoptosis and the mechanisms.

Hui-zhen Wang, Yiqiang Zhang, Zhiguo Wang, 2004, American journal of physiology. Heart and circulatory physiology.

Restoring depressed HERG K+ channel function as a mechanism for insulin treatment of abnormal QT prolongation and associated arrhythmias in diabetic rabbits.

Xiaobin Luo, Jiening Xiao, Zhiguo Wang, 2006, American journal of physiology. Heart and circulatory physiology.

Elevated Protein Carbonylation, and Misfolding in Sciatic Nerve from db/db and Sod1−/− Mice: Plausible Link between Oxidative Stress and Demyelination

Yun Shi, Yiqiang Zhang, R. Buffenstein, 2013, PloS one.

The mammalian target of rapamycin modulates the immunoproteasome system in the heart.

Yiqiang Zhang, Vivian Diaz, R. Hamilton, 2015, Journal of molecular and cellular cardiology.

The Lack of CuZnSOD Leads to Impaired Neurotransmitter Release, Neuromuscular Junction Destabilization and Reduced Muscle Strength in Mice

C. Jaramillo, Yun Shi, Yiqiang Zhang, 2014, PloS one.

Neuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype

K. Sataranatarajan, M. Jackson, Yiqiang Zhang, 2015, Redox biology.

Ionic, cellular and molecular mechanisms underlying the QT prolongation and arrhythmias in diabetic cardiocomplications

Yiqiang Zhang, 2006 .

Potential mechanisms for the enhancement of HERG K+ channel function by phospholipid metabolites

Baofeng Yang, Hui-zhen Wang, S. Nattel, 2004, British journal of pharmacology.

Phospholipid Metabolite 1-Palmitoyl-Lysophosphatidylcholine Enhances Human Ether-a-Go-Go-Related Gene (HERG) K+ Channel Function

Baofeng Yang, Hui-zhen Wang, S. Nattel, 2001, Circulation.

Different Subtypes of α1-Adrenoceptor Modulate Different K+ Currents via Different Signaling Pathways in Canine Ventricular Myocytes*

Baofeng Yang, Hui-zhen Wang, Yiqiang Zhang, 2001, The Journal of Biological Chemistry.

Impairment of HERG K+ Channel Function by Tumor Necrosis Factor-α

Hui-zhen Wang, S. Nattel, Huanhuan Gao, 2004, Journal of Biological Chemistry.

Potential Therapeutic Value of Antioxidants for Abnormal Prolongation of QT Interval and the Associated Arrhythmias in a Rabbit Model of Diabetes

Yanjie Lu, Baofeng Yang, Ying Zhang, 2011, Cellular Physiology and Biochemistry.

The role of mitochondrial complex III in melatonin‐induced ROS production in cultured mesangial cells

Hong-Mei Zhang, Yiqiang Zhang, Bin-Xian Zhang, 2011, Journal of pineal research.

Impairment of Human Ether-à-Go-Go-related Gene (HERG) K+ Channel Function by Hypoglycemia and Hyperglycemia

Baofeng Yang, Hui-zhen Wang, Yiqiang Zhang, 2003, The Journal of Biological Chemistry.

HERG K+ channel, a regulator of tumor cell apoptosis and proliferation.

Baofeng Yang, Hui-zhen Wang, S. Nattel, 2002, Cancer research.

Obesity-induced oxidative stress, accelerated functional decline with age and increased mortality in mice.

D. Sosnowska, Yiqiang Zhang, A. Salmon, 2015, Archives of biochemistry and biophysics.

Clip domain prophenoloxidase activating protease is required for Ostrinia furnacalis Guenée to defend against bacterial infection

Yiqiang Zhang, Zhenying Wang, Haobo Jiang, 2018, Developmental and comparative immunology.

Sevoflurane inhibits neuroblastoma cell proliferation and invasion and induces apoptosis by miR‐144‐3p/YAP1 axis

Yiqiang Zhang, Longqiu Yang, Jun Shen, 2021, Basic & clinical pharmacology & toxicology.

Combined treatment of rapamycin and dietary restriction has a larger effect on the transcriptome and metabolome of liver

W. Wood, K. Becker, W. Fok, 2013, Aging cell.

Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity.

Yan Li, Arlan Richardson, Alex Bokov, 2009, The journals of gerontology. Series A, Biological sciences and medical sciences.

Moderate lifelong overexpression of tuberous sclerosis complex 1 (TSC1) improves health and survival in mice

Yiqiang Zhang, Vivian Diaz, Michael E Walsh, 2017, Scientific Reports.

Short-Term Treatment With Rapamycin and Dietary Restriction Have Overlapping and Distinctive Effects in Young Mice

Dean P. Jones, W. Ward, W. Fok, 2012, The journals of gerontology. Series A, Biological sciences and medical sciences.

The miR-195 Axis Regulates Chemoresistance through TUBB and Lung Cancer Progression through BIRC5

A. Pertsemlidis, J. Kurie, Yiqiang Zhang, 2019, Molecular therapy oncolytics.

Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice.

Dean P. Jones, K. Tominaga, J. Yodoi, 2011, The journals of gerontology. Series A, Biological sciences and medical sciences.

Moderate lifelong overexpression of tuberous sclerosis complex 1 (TSC1) improves health and survival in mice

Yiqiang Zhang, Vivian Diaz, Michael E Walsh, 2017, Scientific Reports.

Long-lived species have improved proteostasis compared to phylogenetically-related shorter-lived species.

S. Austad, Yiqiang Zhang, V. Pérez, 2015, Biochemical and biophysical research communications.

A new role for oxidative stress in aging: The accelerated aging phenotype in Sod1−/− mice is correlated to increased cellular senescence

D. Sosnowska, Yiqiang Zhang, A. Richardson, 2016, Redox biology.

Dietary restriction attenuates the accelerated aging phenotype of Sod1(-/-) mice.

Hong-Mei Zhang, C. Jaramillo, A. Bokov, 2013, Free radical biology & medicine.

MicroRNA miR-133 represses HERG K+ channel expression contributing to QT prolongation in diabetic hearts.

Yanjie Lu, Xiaobin Luo, Huixian Lin, 2011, The Journal of Biological Chemistry.

Hydralazine induces stress resistance and extends C. elegans lifespan by activating the NRF2/SKN-1 signalling pathway

R. Lin, Yiqiang Zhang, Hamid Mirzaei, 2017, Nature Communications.

Hydralazine induces stress resistance and extends C. elegans lifespan by activating the NRF2/SKN-1 signalling pathway

R. Lin, Yiqiang Zhang, Hamid Mirzaei, 2017, Nature Communications.

miR-195 potentiates the efficacy of microtubule-targeting agents in non-small cell lung cancer.

Alexander Pertsemlidis, Xiaojie Yu, A. Pertsemlidis, 2018, Cancer letters.

miR-195 targets cyclin D3 and survivin to modulate the tumorigenesis of non-small cell lung cancer

A. Pertsemlidis, Liqin Du, Yiqiang Zhang, 2018, Cell Death & Disease.

miR-195 targets cyclin D3 and survivin to modulate the tumorigenesis of non-small cell lung cancer

A. Pertsemlidis, Liqin Du, Yiqiang Zhang, 2018, Cell Death & Disease.

Slc43a3 is a regulator of free fatty acid flux1

D. Bernlohr, Yiqiang Zhang, F. Kraemer, 2020, Journal of Lipid Research.

The extreme sensitivity of Mycobacterium tuberculosis to the front-line antituberculosis drug isoniazid

S. Dhandayuthapani, V. Deretic, Yiqiang Zhang, 1996, Nature Biotechnology.

Genetic ablation of 12/15-lipoxygenase but not 5-lipoxygenase protects against denervation-induced muscle atrophy.

Yiqiang Zhang, R. Hamilton, H. Van Remmen, 2014, Free radical biology & medicine.

Liver specific expression of Cu/ZnSOD extends the lifespan of Sod1 null mice

H. Remmen, A. Bokov, Yiqiang Zhang, 2016, Mechanisms of Ageing and Development.

Ionic Mechanisms Underlying Abnormal QT Prolongation and the Associated Arrhythmias in Diabetic Rabbits: A Role of Rapid Delayed Rectifier K+ Current

Xiaobin Luo, Huixian Lin, Jiening Xiao, 2007, Cellular Physiology and Biochemistry.

HERG K+ Channel Conductance Promotes H2O2-Induced Apoptosis in HEK293 Cells: Cellular Mechanisms

Hui-zhen Wang, Yiqiang Zhang, Zhiguo Wang, 2004, Cellular Physiology and Biochemistry.