V. Pérez

发表

Mice Fed Rapamycin Have an Increase in Lifespan Associated with Major Changes in the Liver Transcriptome

W. Wood, K. Becker, W. Fok, 2014, PloS one.

Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat

Yael H. Edrey, B. Friguet, W. Ward, 2009, Proceedings of the National Academy of Sciences.

Is the oxidative stress theory of aging dead?

A. Bokov, V. Pérez, A. Richardson, 2009, Biochimica et biophysica acta.

Molecular Mechanisms of Nrf2 in Inflammation: Interactions Between Nrf2 and Inflammatory Mediators

V. Pérez, Rong Wang, 2020 .

Proteasome modulates mitochondrial function during cellular senescence.

V. Pérez, C. Torres, 2008, Free radical biology & medicine.

The non-receptor tyrosine phosphatase type 14 blocks caveolin-1-enhanced cancer cell metastasis

V. Pérez, V. Torres, L. Leyton, 2020, Oncogene.

Gene expression in the liver of female, but not male mice treated with rapamycin resembles changes observed under dietary restriction

W. Fok, V. Pérez, B. Sunchu, 2015, SpringerPlus.

Mitochondrial Dysfunction and the Glycolytic Switch Induced by Caveolin-1 Phosphorylation Promote Cancer Cell Migration, Invasion, and Metastasis

V. Pérez, L. Leyton, A. Quest, 2022, Cancers.

Brain cellular senescence in mouse models of Alzheimer’s disease

V. Pérez, V. Galvan, Zhen Yu, 2021, GeroScience.

Exploring the effect of redox enzyme modulation on the biology of mouse aging

A. Salmon, V. Pérez, Arlan Richardson, 2014 .

15 How Does Caloric Restriction Increase the Longevity of Mammals

R. Weindruch, R. Colman, V. Pérez, 2008 .

Analysis of autophagic flux in response to sulforaphane in metastatic prostate cancer cells.

David E. Williams, E. Ho, V. Pérez, 2015, Molecular nutrition & food research.

Thioredoxin 2 haploinsufficiency in mice results in impaired mitochondrial function and increased oxidative stress.

V. Pérez, A. Richardson, H. Van Remmen, 2008, Free radical biology & medicine.

Rapamycin and the inhibition of the secretory phenotype

V. Pérez, B. Sunchu, Rong Wang, 2017, Experimental Gerontology.

Cell proliferation arrest and redox state status as part of different stages during senescence establishment in mouse fibroblasts

A. Zentella, V. Pérez, L. Gómez-Quiroz, 2014, Biogerontology.

Aggresome-Like Formation Promotes Resistance to Proteotoxicity in Cells from Long-Lived Species.

V. Pérez, B. Sunchu, Zhen Yu, 2020, The journals of gerontology. Series A, Biological sciences and medical sciences.

The secretory phenotype of senescent astrocytes isolated from Wistar newborn rats changes with anti-inflammatory drugs, but does not have a short-term effect on neuronal mitochondrial potential

V. Pérez, C. Torres, M. Königsberg, 2018, Biogerontology.

Cyclophilin D over-expression increases mitochondrial complex III activity and accelerates supercomplex formation.

V. Pérez, A. Richardson, J. Lechleiter, 2017, Archives of biochemistry and biophysics.

Effect of Nrf2 loss on senescence and cognition of tau-based P301S mice

V. Pérez, J. Valerio, Zhen Yu, 2022, bioRxiv.

Brain cellular senescence in mouse models of Alzheimer’s disease

V. Pérez, V. Galvan, Ruben Riordan, 2021, GeroScience.

Walking the oxidative stress tightrope: a perspective from the naked mole-rat, the longest-living rodent.

Ewa Wywial, Yael H. Edrey, Rochelle Buffenstein, 2011, Current pharmaceutical design.

The overexpression of major antioxidant enzymes does not extend the lifespan of mice

C. Epstein, J. Vijg, A. Bokov, 2008, Aging cell.

Combined treatment of rapamycin and dietary restriction has a larger effect on the transcriptome and metabolome of liver

W. Wood, K. Becker, W. Fok, 2013, Aging cell.

Overexpression of Mn superoxide dismutase does not increase life span in mice.

C. Epstein, Wook Song, A. Salmon, 2009, The journals of gerontology. Series A, Biological sciences and medical sciences.

Cell proliferation arrest and redox state status as part of different stages during senescence establishment in mouse fibroblasts

A. Zentella, V. Pérez, L. Gómez-Quiroz, 2014, Biogerontology.

Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2‐independent mechanism

E. Ho, C. Löhr, V. Pérez, 2017, Aging cell.

Rapamycin and dietary restriction induce metabolically distinctive changes in mouse liver.

W. Fok, A. Salmon, V. Pérez, 2015, The journals of gerontology. Series A, Biological sciences and medical sciences.

Short-term rapamycin treatment in mice has few effects on the transcriptome of white adipose tissue compared to dietary restriction

C. Livi, W. Fok, Yidong Chen, 2014, Mechanisms of Ageing and Development.

Short-Term Treatment With Rapamycin and Dietary Restriction Have Overlapping and Distinctive Effects in Young Mice

Dean P. Jones, W. Ward, W. Fok, 2012, The journals of gerontology. Series A, Biological sciences and medical sciences.

Update on the oxidative stress theory of aging: does oxidative stress play a role in aging or healthy aging?

A. Salmon, V. Pérez, Arlan Richardson, 2010, Free radical biology & medicine.

Lack of methionine sulfoxide reductase A in mice increases sensitivity to oxidative stress but does not diminish life span

R. Levine, A. Bokov, A. Salmon, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice.

Dean P. Jones, K. Tominaga, J. Yodoi, 2011, The journals of gerontology. Series A, Biological sciences and medical sciences.

Long-lived species have improved proteostasis compared to phylogenetically-related shorter-lived species.

S. Austad, Yiqiang Zhang, V. Pérez, 2015, Biochemical and biophysical research communications.

The in vivo gene expression signature of oxidative stress.

C. Epstein, F. Muller, H. Remmen, 2008, Physiological genomics.

Rapamycin impairs bone accrual in young adult mice independent of Nrf2

A. Branscum, Stephen A. Martin, V. Pérez, 2021, Experimental Gerontology.

HDAC6 activity is not required for basal autophagic flux in metastatic prostate cancer cells

David E. Williams, E. Ho, V. Pérez, 2016, Experimental biology and medicine.

Liver specific expression of Cu/ZnSOD extends the lifespan of Sod1 null mice

H. Remmen, A. Bokov, Yiqiang Zhang, 2016, Mechanisms of Ageing and Development.

The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background

Stephen A. Banse, Christine A. Sedore, P. Phillips, 2022, bioRxiv.

Effect of oxygen tension on bioenergetics and proteostasis in young and old myoblast precursor cells☆

V. Pérez, Y. Liu, H. Van Remmen, 2013, Redox biology.

Brain cellular senescence in mouse models of Alzheimer’s disease

V. Pérez, V. Galvan, Ruben Riordan, 2022, GeroScience.

Detection and quantification of protein disulfides in biological tissues a fluorescence-based proteomic approach.

W. Ward, A. Bokov, V. Pérez, 2010, Methods in Enzymology.

Thioredoxin 1 overexpression extends mainly the earlier part of life span in mice.

Dean P. Jones, K. Tominaga, J. Yodoi, 2011, The journals of gerontology. Series A, Biological sciences and medical sciences.

Is the oxidative stress theory of aging dead?

A. Bokov, V. Pérez, A. Richardson, 2009, Biochimica et biophysica acta.