S. Ganesh

发表

Activation of serum/glucocorticoid-induced kinase 1 (SGK1) underlies increased glycogen levels, mTOR activation, and autophagy defects in Lafora disease

P. Singh, Sweta Singh, S. Ganesh, 2013, Molecular biology of the cell.

Mutations in EFHC1 cause juvenile myoclonic epilepsy

M. T. Medina, K. Yamakawa, J. Inazawa, 2004, Nature Genetics.

Guidelines for the use and interpretation of assays for monitoring autophagy

Robert Clarke, Hong Jiang, Hiroyuki Ishida, 2012 .

Emerging nexus between RAB GTPases, autophagy and neurodegeneration

S. Ganesh, N. Jain, Navodita Jain, 2016, Autophagy.

Protein quality control mechanisms and neurodegenerative disorders: Checks, balances and deadlocks

S. Ganesh, Shuchi Mittal, 2010, Neuroscience Research.

Pesticides DEET, fipronil and maneb induce stress granule assembly and translation arrest in neuronal cells

S. Ganesh, R. Parihar, Pratibha Bhadauriya, 2021, Biochemistry and biophysics reports.

Glycogen: the missing link in neuronal autophagy?

S. Ganesh, Akanksha Onkar, Deepashree Sheshadri, 2020, Autophagy.

Lafora disease: from genotype to phenotype

S. Ganesh, R. Parihar, Anupama Rai, 2018, Journal of Genetics.

Autophagy defects in Lafora disease

S. Ganesh, R. Puri, Rajat Puri, 2012, Autophagy.

Phenotype variations in Lafora progressive myoclonus epilepsy: possible involvement of genetic modifiers?

S. Ganesh, Shweta Singh, 2012, Journal of Human Genetics.

Discovery of arginine ethyl ester as polyglutamine aggregation inhibitor: Conformational transitioning of huntingtin N-terminus augments aggregation suppression.

S. Ganesh, I. Roy, R. K. Sharma, 2019, ACS chemical neuroscience.

Increased glucose concentration results in reduced proteasomal activity and the formation of glycogen positive aggresomal structures

S. Ganesh, N. Jain, R. Puri, 2011, The FEBS journal.

Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux

A. Mahadevan, S. Shankar, P. Singh, 2018, Cell Death & Disease.

Lafora disease proteins malin and laforin are recruited to aggresomes in response to proteasomal impairment.

K. Yamakawa, S. Ganesh, Shuchi Mittal, 2007, Human molecular genetics.

Inflammatory system gene polymorphism and the risk of stroke: A case–control study in an Indian population

S. Ganesh, Puneet Agarwal, Veena Gupta, 2008, Brain Research Bulletin.

Association between inflammatory gene polymorphisms and coronary artery disease in an Indian population

S. Ganesh, U. Pandey, R. Parihar, 2007, Journal of Thrombosis and Thrombolysis.

Perinuclear mitochondrial clustering, increased ROS levels, and HIF1 are required for the activation of HSF1 by heat stress

S. Ganesh, Saloni Agarwal, 2020, Journal of Cell Science.

Strategies for Interference of Insulin Fibrillogenesis: Challenges and Advances

S. Ganesh, S. Verma, Shantanu Sen, 2022, Chembiochem : a European journal of chemical biology.

Decreased O-Linked GlcNAcylation Protects from Cytotoxicity Mediated by Huntingtin Exon1 Protein Fragment*

P. Singh, S. Ganesh, Amit Kumar, 2014, The Journal of Biological Chemistry.

Malin and laforin are essential components of a protein complex that protects cells from thermal stress

S. Sengupta, Sweta Singh, S. Ganesh, 2011, Journal of Cell Science.

Satellite III non-coding RNAs show distinct and stress-specific patterns of induction.

S. Sengupta, S. Ganesh, R. Parihar, 2009, Biochemical and biophysical research communications.

Age-Dependent Reduction in the Expression Levels of Genes Involved in Progressive Myoclonus Epilepsy Correlates with Increased Neuroinflammation and Seizure Susceptibility in Mouse Models

S. Ganesh, Priyanka Sinha, Bhupender Verma, 2022, Molecular Neurobiology.

Interdependence of laforin and malin proteins for their stability and functions could underlie the molecular basis of locus heterogeneity in Lafora disease

P. Singh, S. Ganesh, Shuchi Mittal, 2015, Journal of Biosciences.

Association of ADAM33 Gene Polymorphisms with Reduction of Lung Function as Measured by Peak Expiratory Flow Rate Among Healthy Male Smokers and Nonsmokers

S. Awasthi, Priya Tripathi, S. Ganesh, 2012 .

Loss of laforin or malin results in increased Drp1 level and concomitant mitochondrial fragmentation in Lafora disease mouse models

S. Ganesh, Pratibha Bhadauriya, Saloni Agarwal, 2017, Neurobiology of Disease.

Lafora disease E3 ubiquitin ligase malin is recruited to the processing bodies and regulates the microRNA-mediated gene silencing process via the decapping enzyme Dcp1a

P. Singh, Sweta Singh, S. Ganesh, 2012, RNA biology.

Hyperphosphorylation and Aggregation of Tau in Laforin-deficient Mice, an Animal Model for Lafora Disease*

K. Yamakawa, S. Ganesh, Toshimitsu Suzuki, 2009, The Journal of Biological Chemistry.

Alternative splicing modulates subcellular localization of laforin.

K. Yamakawa, S. Ganesh, Toshimitsu Suzuki, 2002, Biochemical and biophysical research communications.

Heat shock modulates the subcellular localization, stability, and activity of HIPK2.

S. Ganesh, Pratibha Bhadauriya, Mamta Upadhyay, 2016, Biochemical and biophysical research communications.

Haplotypic association of ADAM33 (T+1, S+1 and V − 3) gene variants in genetic susceptibility to asthma in Indian population

S. Awasthi, Priya Tripathi, S. Ganesh, 2012, Annals of human biology.

The Laforin-Malin Complex Negatively Regulates Glycogen Synthesis by Modulating Cellular Glucose Uptake via Glucose Transporters

P. Singh, Sweta Singh, S. Ganesh, 2011, Molecular and Cellular Biology.

Association of ADAM33 gene polymorphisms with adult-onset asthma and its severity in an Indian adult population

S. Awasthi, Priya Tripathi, S. Ganesh, 2011 .

Selective Cell Adhesion on Peptide–Polymer Electrospun Fiber Mats

S. Kumari, S. Ganesh, G. Kaur, 2019, ACS Omega.

Blended polar/nonpolar peptide conjugate interferes with human insulin amyloid-mediated cytotoxicity.

S. Ganesh, N. Mishra, S. Verma, 2021, Bioorganic chemistry.

Advances in the genetics of progressive myoclonus epilepsy.

K. Yamakawa, A. Delgado-Escueta, S. Ganesh, 2001, American journal of medical genetics.

Association of the GRM4 gene variants with juvenile myoclonic epilepsy in an Indian population

S. Singh, M. Mehndiratta, S. Ganesh, 2014, Journal Genetika.

Dysfunctions in endosomal-lysosomal and autophagy pathways underlie neuropathology in a mouse model for Lafora disease.

K. Yamakawa, S. Ganesh, Toshimitsu Suzuki, 2012, Human molecular genetics.

Dexamethasone-induced activation of heat shock response ameliorates seizure susceptibility and neuroinflammation in mouse models of Lafora disease

S. Ganesh, Priyanka Sinha, Bhupender Verma, 2021, Experimental Neurology.

Recent advances in the molecular basis of Lafora's progressive myoclonus epilepsy

S. Ganesh, Shweta Singh, Shuchi Mittal, 2006, Journal of Human Genetics.

Modulation of functional properties of laforin phosphatase by alternative splicing reveals a novel mechanism for the EPM2A gene in Lafora progressive myoclonus epilepsy.

S. Ganesh, D. Dubey, 2008, Human molecular genetics.

Transcriptional profiling of a mouse model for Lafora disease reveals dysregulation of genes involved in the expression and modification of proteins

K. Yamakawa, A. Delgado-Escueta, S. Ganesh, 2005, Neuroscience Letters.

Lafora disease proteins laforin and malin negatively regulate the HIPK2-p53 cell death pathway.

S. Ganesh, Pratibha Bhadauriya, Mamta Upadhyay, 2015, Biochemical and biophysical research communications.

The carbohydrate-binding domain of Lafora disease protein targets Lafora polyglucosan bodies.

K. Yamakawa, A. Delgado-Escueta, S. Ganesh, 2004, Biochemical and biophysical research communications.

Suppression of leptin signaling reduces polyglucosan inclusions and seizure susceptibility in a mouse model for Lafora disease

S. Ganesh, Anupama Rai, Rohit Mishra, 2017, Human molecular genetics.

Luminescent EuIII and TbIII Complexes Containing Dopamine Neurotransmitter: Biological Interactions, Antioxidant Activity and Cellular-Imaging Studies

S. Ganesh, A. Patra, Khushbu B. Singh, 2018, European Journal of Inorganic Chemistry.

Sex-biased transgenerational effect of maternal stress on neurodevelopment and cognitive functions

S. Ganesh, P. Misra, 2018, Journal Genetika.

Mercuric Ion Sensing by an Overlapping β‐turn Containing Peptide

S. Ganesh, N. N. Nair, R. Parihar, 2017 .

Mutations in the NHLRC1 gene are the common cause for Lafora disease in the Japanese population

K. Yamakawa, S. Ganesh, Y. Inoue, 2005, Journal of Human Genetics.

Human satellite-III non-coding RNAs modulate heat-shock-induced transcriptional repression

S. Sengupta, M. Mukerji, S. Ganesh, 2016, Journal of Cell Science.

Genotype-phenotype correlations for EPM2A mutations in Lafora's progressive myoclonus epilepsy: exon 1 mutations associate with an early-onset cognitive deficit subphenotype.

M. T. Medina, K. Yamakawa, A. Delgado-Escueta, 2002, Human molecular genetics.

Non-coding RNAs in polyglutamine disorders: friend or foe?

S. Sengupta, S. Ganesh, 2008, Journal of Biosciences.

Mural Cells: Potential Therapeutic Targets to Bridge Cardiovascular Disease and Neurodegeneration

S. Ganesh, A. Misra, S. Patel, 2021, Cells.

Trehalose Ameliorates Seizure Susceptibility in Lafora Disease Mouse Models by Suppressing Neuroinflammation and Endoplasmic Reticulum Stress

S. Ganesh, Priyanka Sinha, Bhupender Verma, 2020, Molecular Neurobiology.

Lafora disease: from genotype to phenotype

S. Ganesh, R. Parihar, Anupama Rai, 2018, Journal of Genetics.

The malin-laforin complex suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system.

P. Singh, S. Sengupta, S. Ganesh, 2009, Human molecular genetics.

Targeted disruption of the Epm2a gene causes formation of Lafora inclusion bodies, neurodegeneration, ataxia, myoclonus epilepsy and impaired behavioral response in mice.

K. Yamakawa, S. Itohara, K. Agarwala, 2002, Human molecular genetics.

The SCN1A gene variants and epileptic encephalopathies

S. Ganesh, R. Parihar, 2013, Journal of Human Genetics.

Role of Long Non-coding RNAs in Cellular Stress Response

S. Ganesh, A. Goenka, 2018 .

Heat Shock-Induced Transcriptional and Translational Arrest in Mammalian Cells

S. Ganesh, R. Parihar, A. Goenka, 2018 .

Neuronal survival in epilepsy: To die or not to die?

S. Ganesh, Shweta Singh, 2005, Journal of Biosciences.

A novel gene in the chromosomal region for juvenile myoclonic epilepsy on 6p12 encodes a brain-specific lysosomal membrane protein.

K. Yamakawa, K. Agarwala, J. Inazawa, 2001, Biochemical and biophysical research communications.

Novel NHLRC1 mutations and genotype–phenotype correlations in patients with Lafora’s progressive myoclonic epilepsy

K. Yamakawa, G. Avanzini, A. Delgado-Escueta, 2006, Journal of Medical Genetics.

Ayurvedic formulations amalaki rasayana and rasa sindoor improve age-associated memory deficits in mice by modulating dendritic spine densities

S. Ganesh, Priyanka Sinha, Bhupender Verma, 2022, Journal of Ayurveda and integrative medicine.

New discoveries in progressive myoclonus epilepsies: a clinical outlook

S. Ganesh, Shweta Bhat, 2018, Expert review of neurotherapeutics.

Laforin in autophagy: A possible link between carbohydrate and protein in Lafora disease?

S. Ganesh, R. Puri, Rajat Puri, 2010, Autophagy.

Laforin, defective in the progressive myoclonus epilepsy of Lafora type, is a dual-specificity phosphatase associated with polyribosomes.

K. Yamakawa, K. Agarwala, T. Hashikawa, 2000, Human molecular genetics.

Alterations in brain glycogen levels influence life-history traits and reduce the lifespan in female Drosophila melanogaster

S. Ganesh, Akanksha Onkar, Deepashree Sheshadri, 2021, Biology open.

Dendritic spine abnormalities correlate with behavioral and cognitive deficits in mouse models of Lafora disease

S. Ganesh, K. Taneja, 2020, The Journal of comparative neurology.

Loss of malin, but not laforin, results in compromised autophagic flux and proteasomal dysfunction in cells exposed to heat shock

S. Ganesh, Anupama Rai, Rohit Mishra, 2016, Cell Stress and Chaperones.

FoxO3a-mediated autophagy is down-regulated in the laforin deficient mice, an animal model for Lafora progressive myoclonus epilepsy.

S. Ganesh, Rohit Mishra, Navodita Jain, 2016, Biochemical and biophysical research communications.

Identification and characterization of novel splice variants of the human EPM2A gene mutated in Lafora progressive myoclonus epilepsy.

S. Ganesh, D. Dubey, R. Parihar, 2012, Genomics.

Lafora progressive myoclonus epilepsy: A meta‐analysis of reported mutations in the first decade following the discovery of the EPM2A and NHLRC1 genes

S. Ganesh, Shweta Singh, 2009, Human mutation.

The Lafora disease gene product laforin interacts with HIRIP5, a phylogenetically conserved protein containing a NifU-like domain.

K. Yamakawa, K. Agarwala, A. Delgado-Escueta, 2003, Human molecular genetics.

Mutation screening for Japanese Lafora's disease patients: identification of novel sequence variants in the coding and upstream regulatory regions of EPM2A gene.

K. Yamakawa, S. Ganesh, S. Hirose, 2001, Molecular and cellular probes.

Polyglucosan Bodies in Aged Brain and Neurodegeneration: Cause or Consequence?

S. Ganesh, Anupama Rai, 2019, Models, Molecules and Mechanisms in Biogerontology.

Tandem repeats in human disorders: mechanisms and evolution.

S. Ganesh, P. Siwach, 2008, Frontiers in bioscience : a journal and virtual library.

Genomic and evolutionary insights into genes encoding proteins with single amino acid repeats.

S. Ganesh, S. Pophaly, P. Siwach, 2006, Molecular biology and evolution.

Recent Developments in the Quest for Myoclonic Epilepsy Genes

M. T. Medina, K. Yamakawa, A. Delgado-Escueta, 2003, Epilepsia.

Regional and developmental expression of Epm2a gene and its evolutionary conservation.

K. Yamakawa, K. Agarwala, A. Delgado-Escueta, 2001, Biochemical and biophysical research communications.

Spatial positions of homopolymeric repeats in the human proteome and their effect on cellular toxicity.

S. Sengupta, S. Ganesh, R. Parihar, 2009, Biochemical and biophysical research communications.

Association of ADAM33 gene polymorphisms with asthma in Indian children

S. Awasthi, Priya Tripathi, S. Ganesh, 2011, Journal of Human Genetics.

Lafora disease in the Indian population: EPM2A and NHLRC1 gene mutations and their impact on subcellular localization of laforin and malin

S. Shankar, P. Satishchandra, S. Ganesh, 2008, Human mutation.

Extending Arms of Insulin Resistance from Diabetes to Alzheimer's Disease: Identification of Potential Therapeutic Targets.

S. Ganesh, R. Sandhir, N. Singhal, 2019, CNS & neurological disorders drug targets.

Dscam is associated with axonal and dendritic features of neuronal cells

K. Yamakawa, K. Agarwala, Y. Tsutsumi, 2001, Journal of neuroscience research.

DSCAM, a highly conserved gene in mammals, expressed in differentiating mouse brain.

K. Yamakawa, K. Agarwala, S. Ganesh, 2001, Biochemical and biophysical research communications.

Correction for Activation of serum/glucocorticoid-induced kinase 1 (SGK1) underlies increased glycogen levels, mTOR activation, and autophagy defects in Lafora disease

P. Singh, Sweta Singh, S. Ganesh, 2014, Molecular Biology of the Cell.

Cloning and functional characterization of DSCAML1, a novel DSCAM-like cell adhesion molecule that mediates homophilic intercellular adhesion.

K. Yamakawa, K. Agarwala, Y. Tsutsumi, 2001, Biochemical and biophysical research communications.

Assignment1 of the gene GRM1 coding for metabotropic glutamate receptor 1 to human chromosome band 6q24 by in situ hybridization

K. Yamakawa, S. Ganesh, K. Amano, 2000, Cytogenetic and Genome Research.

Association of gene polymorphism with genetic susceptibility to stroke in Asian populations: a meta-analysis

S. Ganesh, Veena Gupta, I. Banerjee, 2006, Journal of Human Genetics.

Association of angiotensin-converting enzyme, methylene tetrahydrofolate reductase and paraoxonase gene polymorphism and coronary artery disease in an Indian population.

S. Ganesh, U. Pandey, T. Midha, 2011, Cardiology journal.

[Juvenile myoclonic epilepsy in chromosome 6p12: clinical and genetic advances].

M. T. Medina, K. Yamakawa, A. Delgado-Escueta, 2002, Revista de neurologia.

Isolation and characterization of mouse homologue for the human epilepsy gene, EPM2A.

K. Yamakawa, A. Delgado-Escueta, S. Ganesh, 1999, Biochemical and biophysical research communications.

Autism genes: the continuum that connects us all

S. Ganesh, R. Parihar, 2016, Journal of Genetics.

siRNA Mediated GSK3β Knockdown Targets Insulin Signaling Pathway and Rescues Alzheimer's Disease Pathology: Evidence from In Vitro and In Vivo Studies.

S. Ganesh, R. Sandhir, N. Singhal, 2021, ACS applied materials & interfaces.

Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux

A. Mahadevan, S. Shankar, P. Singh, 2018, Cell Death & Disease.

Mannosylated self-assembled structures for molecular confinement and gene delivery applications.

S. Ganesh, S. Verma, C. Purohit, 2009, Biochemical and biophysical research communications.

Gene defects in progressive myoclonus epilepsy

J. Serratosa, S. Ganesh, B. Minassian, 2010 .

Association of the GRM4 gene variants with juvenile myoclonic epilepsy in an Indian population

M. Mehndiratta, S. Singh, S. Ganesh, 2014, Journal of Genetics.

Evidence for Compromised Insulin Signaling and Neuronal Vulnerability in Experimental Model of Sporadic Alzheimer’s Disease

Shrikant S. Mantri, S. Ganesh, R. Sandhir, 2018, Molecular Neurobiology.

Protein quality control mechanisms and neurodegenerative disorders: Checks, balances and deadlocks

S. Ganesh, Shuchi Mittal, 2010, Neuroscience Research.

Hypothesis ___________________________________________________________________________ Identification and Comparative Analysis of Novel Alternatively Spliced Transcripts of Rhogef Domain Encoding Gene in C. Elegans and C. Briggsae

S. Ganesh, M. Tabish, D. Dubey, 2022 .

The Laforin-Malin Complex Negatively Regulates Glycogen Synthesis by Modulating Cellular Glucose Uptake via Glucose Transporters

P. Singh, Sweta Singh, S. Ganesh, 2011, Molecular and Cellular Biology.

Progressive myoclonus epilepsy of Lafora

J. Serratosa, S. Ganesh, B. Minassian, 2012 .

Autophagy defects in Lafora disease

S. Ganesh, Rajat Puri, 2012, Autophagy.

Evidence for Compromised Insulin Signaling and Neuronal Vulnerability in Experimental Model of Sporadic Alzheimer’s Disease

Shrikant S. Mantri, S. Ganesh, R. Sandhir, 2018, Molecular Neurobiology.