Pamela Leal

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AKT/mTOR substrate P70S6K is frequently phosphorylated in gallbladder cancer tissue and cell lines

J. Roa, Pamela Leal, P. García, 2013, OncoTargets and therapy.

Effects of clopidogrel on inflammatory cytokines and adhesion molecules in human endothelial cells: Role of nitric oxide mediating pleiotropic effects

M. Hirata, L. Salazar, Pamela Leal, 2017, Cardiovascular therapeutics.

Inhibition of connective tissue growth factor (CTGF/CCN2) in gallbladder cancer cells leads to decreased growth in vitro

J. Roa, Pamela Leal, P. García, 2013, International journal of experimental pathology.

Connective tissue growth factor immunohistochemical expression is associated with gallbladder cancer progression.

J. Roa, Pamela Leal, P. García, 2013, Archives of pathology & laboratory medicine.

Controlled Release of Caffeic Acid and Pinocembrin by Use of nPSi-βCD Composites Improves Their Antiangiogenic Activity

Pamela Leal, Helga Weber, M. Alvear, 2022, Pharmaceutics.

Anthocyanin-Rich Extracts of Calafate (Berberis microphylla G. Forst.) Fruits Decrease In Vitro Viability and Migration of Human Gastric and Gallbladder Cancer Cell Lines

Pamela Leal, I. Riquelme, M. Alberdi, 2020, Journal of Soil Science and Plant Nutrition.

Cellular FLICE-like Inhibitory Protein Long Form (c-FLIPL) Overexpression is Related to Cervical Cancer Progression

D. Sidransky, R. Guerrero-Preston, J. Roa, 2013, International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.

Characterization of microbial communities from gut microbiota of hypercholesterolemic and control subjects

F. Lanas, N. Saavedra, L. Salazar, 2022, Frontiers in Cellular and Infection Microbiology.

Hippo-YAP1 Is a Prognosis Marker and Potentially Targetable Pathway in Advanced Gallbladder Cancer

J. Roa, Pamela Leal, P. García, 2020, Cancers.

Functional and genomic characterization of three novel cell lines derived from a metastatic gallbladder cancer tumor

J. Roa, Pamela Leal, P. García, 2020, Biological Research.

Mucin 5B, carbonic anhydrase 9 and claudin 18 are potential theranostic markers of gallbladder carcinoma

J. Roa, Pamela Leal, P. García, 2019, Histopathology.

Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506-binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population

R. Irizarry, L. van Neste, D. Sidransky, 2014, Epigenetics.

The ERK/MAPK pathway is overexpressed and activated in gallbladder cancer.

J. Araya, J. Roa, Pamela Leal, 2017, Pathology, research and practice.

Targeting specific molecular pathways holds promise for advanced gallbladder cancer therapy.

J. Roa, Pamela Leal, P. García, 2015, Cancer treatment reviews.

Immunohistochemical expression of phospho-mTOR is associated with poor prognosis in patients with gallbladder adenocarcinoma.

J. Roa, Pamela Leal, P. García, 2013, Archives of pathology & laboratory medicine.

The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance

E. Bellolio, J. Roa, Pamela Leal, 2014, Virchows Archiv.

miR-1 and miR-145 act as tumor suppressor microRNAs in gallbladder cancer.

J. Roa, Pamela Leal, P. García, 2014, International journal of clinical and experimental pathology.

Immunohistochemical Expression of Vascular Endothelial Growth Factor A in Advanced Gallbladder Carcinoma

J. Roa, Pamela Leal, P. García, 2014, Applied immunohistochemistry & molecular morphology : AIMM.

Genotyping of human papillomavirus in cervical intraepithelial neoplasia in a high‐risk population

J. Roa, Pamela Leal, P. García, 2011, Journal of medical virology.

miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway

J. Araya, R. Peek, J. Roa, 2015, Cellular Oncology.

The Gene Expression Status of the PI3K/AKT/mTOR Pathway in Gastric Cancer Tissues and Cell Lines

J. Araya, R. Peek, J. Roa, 2016, Pathology & Oncology Research.

Identification of prosaposin and transgelin as potential biomarkers for gallbladder cancer using quantitative proteomics.

Nandini A. Sahasrabuddhe, A. Pandey, S. Navani, 2014, Biochemical and biophysical research communications.

Rapamycin and WYE-354 suppress human gallbladder cancer xenografts in mice

J. Araya, J. Roa, Pamela Leal, 2015, Oncotarget.

A Novel Gemcitabine-Resistant Gallbladder Cancer Model Provides Insights into Molecular Changes Occurring during Acquired Resistance

G. Repetto, J. Roa, Pamela Leal, 2023, International journal of molecular sciences.

miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway

J. Araya, R. Peek, J. Roa, 2016, Cellular Oncology.

Identification and characterization of three novel cold acclimation-responsive genes from the extremophile hair grass Deschampsia antarctica Desv.

M. Gidekel, A. Gutiérrez, L. Bravo, 2003, Extremophiles.

Functional and genomic characterization of three novel cell lines derived from a metastatic gallbladder cancer tumor

J. Roa, Pamela Leal, P. García, 2020, Biological Research.

Cytotoxic Effect of Double Emulsion (W/O/W) CuSO4 Loaded PLA Nanoparticles on MKN-45 Gastric Adenocarcinoma Cell Line

Pamela Leal, Enrique Montiel-Eulefi, F. Jara, 2014 .

Therapeutic Targets of Monoclonal Antibodies Used in the Treatment of Cancer: Current and Emerging

Pamela Leal, Helga Weber, C. Manterola, 2023, Biomedicines.

The Anti-Proliferative and Anti-Invasive Effect of Leaf Extracts of Blueberry Plants Treated with Methyl Jasmonate on Human Gastric Cancer In Vitro Is Related to Their Antioxidant Properties

R. Peek, J. Roa, Pamela Leal, 2020, Antioxidants.