T. Back

发表

mTOR kinase inhibitor AZD8055 enhances the immunotherapeutic activity of an agonist CD40 antibody in cancer treatment.

J. Weiss, S. Guichard, Q. Jiang, 2011, Cancer research.

Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment

F. Marincola, A. Dzutsev, Y. Belkaid, 2013, Science.

Inhibiting Janus Kinase 1 and BCL-2 to treat T cell acute lymphoblastic leukemia with IL7-Rα mutations

S. Durum, Wenqing Li, T. Back, 2018, Oncotarget.

Immunologic and Therapeutic Synergy of IL-27 and IL-2: Enhancement of T Cell Sensitization, Tumor-Specific CTL Reactivity and Complete Regression of Disseminated Neuroblastoma Metastases in the Liver and Bone Marrow1

G. Trinchieri, R. Kastelein, J. Wigginton, 2009, The Journal of Immunology.

Bone Marrow Neuroblastoma Metastases in the Liver and and Complete Regression of Disseminated Sensitization , Tumor-Specific CTL Reactivity IL-27 and IL-2 : Enhancement of T Cell Immunologic and Therapeutic Synergy of and

G. Trinchieri, R. Kastelein, J. Wigginton, 2009 .

Synergistic Engagement of an Ineffective Endogenous Anti-Tumor Immune Response and Induction of IFN-γ and Fas-Ligand-Dependent Tumor Eradication by Combined Administration of IL-18 and IL-21

W. Alvord, J. Wigginton, T. Back, 2002, The Journal of Immunology.

Nitric oxide is a key component in inflammation-accelerated tumorigenesis.

Leah E. Mechanic, J. Weiss, C. Harris, 2008, Cancer research.

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model.

D. Wink, R. Cheng, L. Ridnour, 2020, Journal of visualized experiments : JoVE.

Macrophage-dependent nitric oxide expression regulates tumor cell detachment and metastasis after IL-2/anti-CD40 immunotherapy

J. Weiss, C. Harris, D. Wink, 2010, The Journal of experimental medicine.

The pivotal role of IKKα in the development of spontaneous lung squamous cell carcinomas.

Travis J Cohoon, Kwok-Kin Wong, G. Trinchieri, 2013, Cancer cell.

Coactivation of AKT and β-catenin in mice rapidly induces formation of lipogenic liver tumors.

S. Thorgeirsson, J. Weiss, J. Stauffer, 2011, Cancer research.

Antitumor effects of interleukin-7 and adoptive immunotherapy on human colon carcinoma xenografts.

D. Longo, T. Sayers, T. Back, 1993, The Journal of clinical investigation.

Inhibition of early murine hemopoietic progenitor cell proliferation after in vivo locoregional administration of transforming growth factor-beta 1.

D. Longo, F. Ruscetti, T. Back, 1989, Journal of immunology.

Engraftment and activity of anti-CD3-activated human peripheral blood lymphocytes transferred into mice with severe combined immune deficiency.

D. Longo, T. Sayers, T. Back, 1993, Journal of immunology.

Augmentation of natural killer activity, induction of IFN and development tumor immunity during the successful treatment of established murine renal cancer using flavone acetic acid and IL-2.

D. Longo, W. Urba, T. Back, 1988, Journal of immunology.

Apoptotic Potential of Cytokine Therapy for Proteasome Inhibition to Maximize the

S. Lockett, J. Wigginton, J. Stauffer, 2013 .

Proteasome Inhibition to Maximize the Apoptotic Potential of Cytokine Therapy for Murine Neuroblastoma Tumors1

S. Lockett, J. Wigginton, T. Sayers, 2006, The Journal of Immunology.

Proteasome inhibition to maximize the apoptotic potential of cytokine therapy for murine neuroblastoma tumors.

S. Lockett, J. Wigginton, T. Sayers, 2004, Journal of immunology.

Prevention of acute chemotherapy-induced death in mice by recombinant human interleukin 1: protection from hematological and nonhematological toxicities.

D. Longo, F. Ruscetti, G. Damia, 1992, Cancer research.

In vivo distribution and cytokine gene expression by enriched mouse LAK effector cells

H. Young, H. Futami, T. Back, 1991, Biotherapy.

T cell- and NK cell-independent inhibition of hepatic metastases by systemic administration of an IL-12-expressing recombinant adenovirus.

W. Alvord, R. Fenton, T. Back, 1998, Journal of immunology.

Mice with a targeted mutation in lymphotoxin-alpha exhibit enhanced tumor growth and metastasis: impaired NK cell development and recruitment.

D. Ito, T. Back, R. Wiltrout, 1999, Journal of immunology.

Radioimmunotherapy of nude mice with intraperitoneally growing ovarian cancer xenograft utilizing 211At-labelled monoclonal antibody MOv18.

T. Back, L. Jacobsson, H. Andersson, 2000, Anticancer research.

Flavone-8-acetic acid augments systemic natural killer cell activity and synergizes with IL-2 for treatment of murine renal cancer.

M. Boyd, T. Back, R. Wiltrout, 1988, Journal of immunology.

Administration of recombinant human IL-7 to mice alters the composition of B-lineage cells and T cell subsets, enhances T cell function, and induces regression of established metastases.

T. Back, R. Wiltrout, C. Faltynek, 1994, Journal of immunology.

Synergistic Anti-Tumor Responses After Administration of Agonistic Antibodies to CD40 and IL-2: Coordination of Dendritic and CD8+ Cell Responses 1

J. Wigginton, T. Sayers, T. Back, 2003, The Journal of Immunology.

IFN-γ mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy

J. Weiss, D. Longo, T. Back, 2007, Nature Medicine.

TCR-Dependent and -Independent Activation Underlie Liver-Specific Regulation of NKT Cells

J. Weiss, T. Back, T. Chan, 2011, The Journal of Immunology.

Underlie Liver-Specific Regulation of NKT TCR-Dependent and -Independent Activation

J. Weiss, T. Back, T. Chan, 2010 .

Modulation of lymphocyte function with inhibitory CD2: loss of NK and NKT cells.

H. Young, F. Ruscetti, T. Back, 2007, Cellular immunology.

Regulatory T Cells and Myeloid-Derived Suppressor Cells in the Tumor Microenvironment Undergo Fas-Dependent Cell Death during IL-2/αCD40 Therapy

J. Weiss, T. Sayers, S. K. Watkins, 2014, The Journal of Immunology.

Regulatory T Cells and Myeloid-Derived Suppressor Cells in the Tumor Microenvironment Undergo Fas-Dependent Cell Death during IL-2/aCD40 Therapy

J. Weiss, T. Sayers, S. K. Watkins, 2014 .

Cell Death during IL-2/ Microenvironment Undergo Fas-Dependent Suppressor Cells in the Tumor Regulatory T Cells and Myeloid-Derived

J. Weiss, T. Sayers, S. K. Watkins, 2014 .

Administration of interleukin 12 with pulse interleukin 2 and the rapid and complete eradication of murine renal carcinoma.

J. Franco, J. Wigginton, T. Back, 1996, Journal of the National Cancer Institute.

IFN- γ and Fas/FasL are required for the antitumor and antiangiogenic effects of IL-12/pulse IL-2 therapy Systemic administration of IL-12 and intermittent doses of IL-2

K. Nagashima, J. Wigginton, Jong-Wook Park, 2022 .

Mammary Epithelial Apoptosis Expression , Infiltration , Fas / Fas Ligand Gene IL-12 / Pulse IL-2 : Induction of Local T Cell Programmed Neoplastic Transition by Therapeutic Prevention of Genetically Spontaneous Mammary Carcinoma and the Complete Regression of Established

J. Ward, R. Strieter, J. Wigginton, 2000 .

Successful immunotherapy with IL-2/anti-CD40 induces the chemokine-mediated mitigation of an immunosuppressive tumor microenvironment

J. Weiss, J. Stauffer, T. Back, 2009, Proceedings of the National Academy of Sciences.

Lack of FasL-mediated killing leads to in vivo tumor promotion in mouse Lewis lung cancer

J. Wigginton, T. Sayers, T. Back, 2003, Apoptosis.

IFN-γ-Dependent Delay of In Vivo Tumor Progression by Fas Overexpression on Murine Renal Cancer Cells1 2

J. Wigginton, T. Sayers, A. Brooks, 2000, The Journal of Immunology.

Murine Renal Cancer Cells Progression by Fas Overexpression on-Dependent Delay of In Vivo Tumor

J. Wigginton, T. Sayers, A. Brooks, 1999 .

Enhanced antitumor response by divergent modulation of natural killer and natural killer T cells in the liver.

T. Back, J. Ortaldo, R. Wiltrout, 2006, Cancer research.

of an IL-12-Expressing Recombinant Adenovirus Hepatic Metastases by Systemic Administration T Cell- and NK Cell-Independent Inhibition of

T. Back, R. Wiltrout, P. Wright, 2013 .

Regulation of bone marrow cell survival in short-term cultures: a new macrophage function.

T. Back, E. Blasi, L. Varesio, 1987, Cellular immunology.

Interleukin 12 primes macrophages for nitric oxide production in vivo and restores depressed nitric oxide production by macrophages from tumor-bearing mice: implications for the antitumor activity of interleukin 12 and/or interleukin 2.

J. Wigginton, D. Kuhns, T. Back, 1996, Cancer research.

Evaluation of the Antitumor Activity of the Interleukin‐12/Pulse Interleukin‐2 Combination a

J. Franco, J. Green, J. Wigginton, 1996, Annals of the New York Academy of Sciences.

Successful treatment of advanced murine renal cell cancer by bicompartmental adoptive chemoimmunotherapy.

T. Back, R. Wiltrout, R. Salup, 1987, Journal of immunology.

Tumor-Specific CTL Kill Murine Renal Cancer Cells Using Both Perforin and Fas Ligand-Mediated Lysis In Vitro, But Cause Tumor Regression In Vivo in the Absence of Perforin1

T. Sayers, A. Brooks, M. Smyth, 2002, The Journal of Immunology.

Complete Regression of Established Spontaneous Mammary Carcinoma and the Therapeutic Prevention of Genetically Programmed Neoplastic Transition by IL-12/Pulse IL-2: Induction of Local T Cell Infiltration, Fas/Fas Ligand Gene Expression, and Mammary Epithelial Apoptosis1 2

J. Ward, R. Strieter, J. Wigginton, 2001, The Journal of Immunology.

High-Throughput Molecular and Histopathologic Profiling of Tumor Tissue in a Novel Transplantable Model of Murine Neuroblastoma: New Tools for Pediatric Drug Discovery

Jun S. Wei, J. Wigginton, R. Orentas, 2012, Cancer investigation.

Multicolor Fluorescence-Based Approaches for Imaging Cytokine-Induced Alterations in the Neovascularization, Growth, Metastasis, and Apoptosis of Murine Neuroblastoma Tumors

J. Wigginton, J. Stauffer, T. Back, 2006, Journal of immunotherapy.

Systemic IL-12 Administration Alters Hepatic Dendritic Cell Stimulation Capabilities

J. Weiss, T. Back, T. Chan, 2012, PloS one.

Cell Responses + and CD8 CD40 and IL-2: Coordination of Dendritic Administration of Agonistic Antibodies to Synergistic Anti-Tumor Responses After

J. Wigginton, T. Sayers, T. Back, 2003 .

IFN-gamma-dependent delay of in vivo tumor progression by Fas overexpression on murine renal cancer cells.

J. Wigginton, T. Sayers, A. Brooks, 2000, Journal of immunology.

Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene.

A. Vortmeyer, L. Schmidt, B. Zbar, 2003, Cancer research.

Gene VHL Inactivation of the Impaired Spermatogenesis in Mice with Conditional Hepatic Vascular Tumors , Angiectasis in Multiple Organs , and Updated

A. Vortmeyer, L. Schmidt, B. Zbar, 2003 .

Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma

A. Schetter, J. Weiss, A. Maitra, 2013, International journal of cancer.

LTβR signalling preferentially accelerates oncogenic AKT-initiated liver tumours

X. Wang, J. Weiss, C. Ware, 2015, Gut.

Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins

R. Chari, T. Sayers, A. Brooks, 2021, Cancer Research.

Therapeutic modulation of Akt activity and antitumor efficacy of interleukin-12 against orthotopic murine neuroblastoma.

K. Nagashima, S. Lockett, J. Wigginton, 2006, Journal of the National Cancer Institute.

Stimulation through CD40 on Mouse and Human Renal Cell Carcinomas Triggers Cytokine Production, Leukocyte Recruitment, and Antitumor Responses that Can Be Independent of Host CD40 Expression12

J. Weiss, T. Back, R. Wiltrout, 2006, The Journal of Immunology.

Cytokine Production , Leukocyte Human Renal Cell Carcinomas Triggers Stimulation through CD 40 on Mouse and

J. Weiss, T. Back, R. Wiltrout, 2006 .

Stimulation through CD 40 on Mouse and Human Renal Cell Carcinomas Triggers Cytokine Production , Leukocyte Recruitment , and Antitumor Responses that Can Be Independent of Host CD 40 Expression 1 , 2

J. Weiss, T. Back, R. Wiltrout, 2006 .

In Vivo Regulation of Experimental Autoimmune Encephalomyelitis by NK Cells: Alteration of Primary Adaptive Responses12

H. Young, T. Back, J. Ortaldo, 2008, The Journal of Immunology.

Combined Administration of IL-18 and IL-2 byFas-Ligand-Dependent Tumor Eradication and γ and Induction of IFN-Endogenous Anti-Tumor Immune Response Synergistic Engagement of an Ineffective

W. Alvord, J. Wigginton, T. Back, 2002 .

Mutant IL-7Rα and mutant NRas are sufficient to induce murine T cell acute lymphoblastic leukemia

D. Esposito, S. Durum, Wenqing Li, 2018, Leukemia.

Serum-based tracking of de novo initiated liver cancer progression reveals early immunoregulation and response to therapy.

J. Weiss, J. Stauffer, Q. Jiang, 2015, Journal of hepatology.

IFN-gamma and Fas/FasL are required for the antitumor and antiangiogenic effects of IL-12/pulse IL-2 therapy.

J. Wigginton, T. Back, R. Wiltrout, 2001, The Journal of clinical investigation.

Induction of transplantable mouse renal cell cancers by streptozotocin: in vivo growth, metastases, and angiogenic phenotype.

J. Ward, J. Wigginton, T. Back, 2001, Cancer research.

IL-27 Mediates Complete Regression of Orthotopic Primary and Metastatic Murine Neuroblastoma Tumors: Role for CD8+ T Cells1

R. Kastelein, J. Wigginton, J. Stauffer, 2004, The Journal of Immunology.

Alpha synuclein, the culprit in Parkinson disease, is required for normal immune function.

T. Back, J. Oppenheim, D. Barbut, 2022, Cell reports.

Abstract 1083: The pivotal role of IKKalpha in the development of spontaneous lung squamous cell carcinomas.

R. Goldszmid, S. Xi, D. Schrump, 2013 .