D. Ganem

C. Langefeld, K. Skorecki, J. Divers, 2018, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Evidence for activation of the hepatitis B virus polymerase by binding of its RNA template

J. Tavis, D. Ganem, Don Ganem, 1996, Journal of virology.

polymerase by binding of its RNA template . Evidence for activation of the hepatitis B virus

J. Tavis, D. Ganem, 1996 .

Activation of a nonclassical NKT cell subset in a transgenic mouse model of hepatitis B virus infection.

R. Locksley, D. Ganem, S. Nishimura, 2002, Immunity.

The molecular biology of the hepatitis B viruses.

H. Varmus, D. Ganem, 1987, Annual review of biochemistry.

Identification of the gene encoding the major latency-associated nuclear antigen of the Kaposi's sarcoma-associated herpesvirus.

D. Ganem, D. Kedes, R. Renne, 1997, The Journal of clinical investigation.

Frequent presence of a novel herpesvirus genome in lesions of human immunodeficiency virus-negative Kaposi's sarcoma.

R. Grant, D. Ganem, S. Chuck, 1996, The Journal of infectious diseases.

Antibodies to human herpesvirus 8 in women and infants born in Haiti and the USA

J. Goedert, D. Ganem, D. Kedes, 1997, The Lancet.

Absence of detectable human herpesvirus 8 in the semen of human immunodeficiency virus-infected men without Kaposi's sarcoma.

L. Corey, D. Ganem, J. Krieger, 1997, The Journal of infectious diseases.

gp180, a Protein That Binds Duck Hepatitis B Virus Particles, Has Metallocarboxypeptidase D-like Enzymatic Activity*

F. Eng, D. Ganem, L. Fricker, 1998, The Journal of Biological Chemistry.

gp180, a Host Cell Glycoprotein That Binds Duck Hepatitis B Virus Particles, Is Encoded by a Member of the Carboxypeptidase Gene Family (*)

C. Turck, F. Eng, D. Ganem, 1995, The Journal of Biological Chemistry.

Analysis of the binding of a host cell surface glycoprotein to the preS protein of duck hepatitis B virus.

J. Summers, D. Ganem, R. Lenhoff, 1994, Virology.

Definition of an optimal cytotoxic T lymphocyte epitope in the latently expressed Kaposi's sarcoma-associated herpesvirus kaposin protein.

B. Walker, A. Sette, C. Brander, 2001, The Journal of infectious diseases.

A unique herpesviral transcriptional program in KSHV-infected lymphatic endothelial cells leads to mTORC1 activation and rapamycin sensitivity.

D. Ganem, Henry H. Chang, 2013, Cell host & microbe.

On the control of late gene expression in Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8).

D. Ganem, J. Chang, 2000, The Journal of general virology.

Kaposi's Sarcoma-Associated Herpesvirus Open Reading Frame 57 Encodes a Posttranscriptional Regulator with Multiple Distinct Activities

D. Ganem, Jean Chang, D. Lukac, 2000, Journal of Virology.

AIDS: Viruses, cytokines and Kaposi's sarcoma

D. Ganem, 1995, Current Biology.

Nucleotide sequence of an infectious molecularly cloned genome of ground squirrel hepatitis virus

H. Varmus, D. Ganem, C. Seeger, 1984, Journal of virology.

A cell surface protein that binds avian hepatitis B virus particles

P. Marion, D. Ganem, R. Cheung, 1994, Journal of virology.

Inhibition of duck hepatitis B virus replication by interferon‐γ

D. Ganem, J. Lavine, Don Ganem, 1993, Journal of medical virology.

Cloning andCharacterization ofRNA Polymerase CoreSubunits of Chlamydia trachomatis byUsingthePolymerase ChainReaction

J. Pollack, J. Engel, D. Ganem, 1990 .

Human Enterovirus 109: a Novel Interspecies Recombinant Enterovirus Isolated from a Case of Acute Pediatric Respiratory Illness in Nicaragua

J. Derisi, E. Harris, P. Skewes-Cox, 2010, Journal of Virology.

Regulation of CD1d expression and function by a herpesvirus infection.

D. Ganem, J. Gumperz, D. J. Sanchez, 2005, The Journal of clinical investigation.

Transcriptional Activation by the Product of Open Reading Frame 50 of Kaposi’s Sarcoma-Associated Herpesvirus Is Required for Lytic Viral Reactivation in B Cells

D. Ganem, D. Lukac, J. Kirshner, 1999, Journal of Virology.

DNA Binding by Kaposi's Sarcoma-Associated Herpesvirus Lytic Switch Protein Is Necessary for Transcriptional Activation of Two Viral Delayed Early Promoters

D. Ganem, D. Lukac, J. Kirshner, 2001, Journal of Virology.

Reactivation of Kaposi's sarcoma-associated herpesvirus infection from latency by expression of the ORF 50 transactivator, a homolog of the EBV R protein.

D. Ganem, R. Renne, D. Lukac, 1998, Virology.

Mapping the major transcripts of ground squirrel hepatitis virus: the presumptive template for reverse transcriptase is terminally redundant

H. Varmus, G. Enders, D. Ganem, 1985, Cell.

Transcription of the hepatitis B surface antigen gene in cultured murine cells initiates within the presurface region

W. Rutter, H. Varmus, D. Ganem, 1984, Journal of virology.

Closed circular viral DNA and asymmetrical heterogeneous forms in livers from animals infected with ground squirrel hepatitis virus

H. Varmus, D. Ganem, C. Seeger, 1983, Journal of virology.

Biological characterization of acute infection with ground squirrel hepatitis virus

H. Varmus, D. Ganem, A. Barchuk, 1982, Journal of virology.

Replication of duck hepatitis B virus in two differentiated human hepatoma cell lines after transfection with cloned viral DNA.

D. Ganem, R. Colgrove, R. Hirsch, 1988, Virology.

Chlamydial rRNAOperons: GeneOrganization andIdentification of Putative TandemPromoters

D. Ganem, 1987 .

Experimental Transmission of Kaposi's Sarcoma–Associated Herpesvirus (Kshv/Hhv-8) to Scid-Hu Thy/Liv Mice

J. McCune, D. Dittmer, D. Ganem, 1999, The Journal of experimental medicine.

Homologous recombination between hepadnaviral genomes following in vivo DNA transfection: implications for studies of viral infectivity.

H. Varmus, R. Sprengel, D. Ganem, 1987, Virology.

Hepadnavirus reverse transcription initiates within the stem-loop of the RNA packaging signal and employs a novel strand transfer

J. Tavis, D. Ganem, S. Perri, 1994, Journal of virology.

Activation of NF-κB by the Latent vFLIP Gene of Kaposi's Sarcoma-Associated Herpesvirus Is Required for the Spindle Shape of Virus-Infected Endothelial Cells and Contributes to Their Proinflammatory Phenotype

M. Skobe, D. Ganem, C. Grossmann, 2006, Journal of Virology.

A Cluster of Latently Expressed Genes in Kaposi’s Sarcoma-Associated Herpesvirus

A. Haase, D. Dittmer, D. Ganem, 1998, Journal of Virology.

Site-Specific Association with Host and Viral Chromatin by Kaposi's Sarcoma-Associated Herpesvirus LANA and Its Reversal during Lytic Reactivation

Meghan M. Holdorf, C. Arias, D. Ganem, 2014, Journal of Virology.

Sensitivity of Kaposi's sarcoma-associated herpesvirus replication to antiviral drugs. Implications for potential therapy.

D. Ganem, D. Kedes, 1997, The Journal of clinical investigation.

Construction and Manipulation of a New Kaposi's Sarcoma-Associated Herpesvirus Bacterial Artificial Chromosome Clone

T. Oh, Jihyun F. Kim, Shou-Jiang Gao, 2012, Journal of Virology.

Human herpesvirus 8 and its role in the genesis of Kaposi's sarcoma.

D. Ganem, 1998, Current clinical topics in infectious diseases.

An advance in liver-specific gene delivery.

D. Ganem, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Sequences 5' to the polyadenylation signal mediate differential poly(A) site use in hepatitis B viruses.

D. Ganem, R. Russnak, 1990, Genes & development.

Activation of N-myc2 gene expression by cis-acting elements of oncogenic hepadnaviral genomes: key role of enhancer II.

D. Ganem, K. Ueda, Y. Wei, 1996, Virology.

Inhibition of secretion of hepatitis B surface antigen by a related presurface polypeptide.

H. Varmus, D. Persing, D. Ganem, 1986, Science.

Mechanism of translation of the hepadnaviral polymerase (P) gene.

H. Varmus, Lung-Ji Chang, D. Ganem, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Site-specific RNA binding by a hepatitis B virus reverse transcriptase initiates two distinct reactions: RNA packaging and DNA synthesis

J. Pollack, D. Ganem, Don Ganem, 1994, Journal of virology.

Host shutoff during productive Epstein–Barr virus infection is mediated by BGLF5 and may contribute to immune evasion

M. Ressing, M. Rowe, D. Ganem, 2007, Proceedings of the National Academy of Sciences.

The Exonuclease and Host Shutoff Functions of the SOX Protein of Kaposi's Sarcoma-Associated Herpesvirus Are Genetically Separable

D. Ganem, B. Glaunsinger, Leonard Chavez, 2005, Journal of Virology.

Highly Selective Escape from KSHV-mediated Host mRNA Shutoff and Its Implications for Viral Pathogenesis

D. Ganem, B. Glaunsinger, 2004, The Journal of experimental medicine.

Hepatitis B surface antigen: an unusual secreted protein initially synthesized as a transmembrane polypeptide

V. Lingappa, D. Ganem, B. Eble, 1986, Molecular and cellular biology.

The preS1 protein of hepatitis B virus is acylated at its amino terminus with myristic acid

H. Varmus, D. Persing, D. Ganem, 1987, Journal of virology.

A developmentally regulated chlamydial gene with apparent homology to eukaryotic histone H1.

J. Engel, D. Ganem, E. Perara, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Experimental transmission of Kaposi's sarcoma‐associated herpesvirus (KSHV/HHV‐8) to SIV‐positive and SIV‐negative rhesus macaques

R. Desrosiers, P. Luciw, D. Dittmer, 2004, Journal of medical primatology.

In vitro recombinants of ground squirrel and woodchuck hepatitis viral DNAs produce infectious virus in squirrels

H. Varmus, P. Marion, D. Ganem, 1987, Journal of virology.

Achalasia and Viral Infection: New Insights from Veterinary Medicine

J. Derisi, D. Ganem, A. Kistler, 2010, Science Translational Medicine.

A developmentally regulated chlamydial gene with apparent homology to eukaryotic histone H 1 ( Chlamydia trachomatis )

D. Ganem, E. Perara, Joanne N. ENGELt, 2022 .

Serological Evidence of Human Klassevirus Infection

J. Derisi, G. Kang, D. Ganem, 2010, Clinical and Vaccine Immunology.

Chlamydial gene encoding a 70-kilodalton antigen in Escherichia coli: analysis of expression signals and identification of the gene product

J. Engel, D. Ganem, L. Sardinia, 1989, Journal of bacteriology.

Hepatitis B virus reverse transcriptase and its many roles in hepadnaviral genomic replication.

J. Pollack, J. Tavis, D. Ganem, 1994, Infectious agents and disease.

Hepatitis Delta Virus Replication Generates Complexes of Large Hepatitis Delta Antigen and Antigenomic RNA That Affiliate with and Alter Nuclear Domain 10

R. Brazas, D. Ganem, G. Maul, 2000, Journal of Virology.

Of marmots and men

D. Ganem, 1990, Nature.

Active lytic infection of human primary tonsillar B cells by KSHV and its noncytolytic control by activated CD4+ T cells.

D. Ganem, J. Myoung, 2011, The Journal of clinical investigation.

Nucleotide Sequence ofan Infectious Molecularly ClonedGenome ofGroundSquirrel Hepatitis Virus

D. Ganem, C. Seeger, 1984 .

Deregulated signal transduction by the K1 gene product of Kaposi's sarcoma-associated herpesvirus.

R. Majeti, A. Weiss, D. Ganem, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Developmental regulation of the cysteine-rich outer-membrane proteins of murine Chlamydia trachomatis.

D. Ganem, E. Segal, L. Sardinia, 1988, Journal of General Microbiology.

A dramatic shift in the transmembrane topology of a viral envelope glycoprotein accompanies hepatitis B viral morphogenesis.

P. Hearing, D. Ganem, P. Ostapchuk, 1994, The EMBO journal.

Activation of Heterologous Gene Expression by the Large Isoform of Hepatitis Delta Antigen

D. Ganem, Yu Wei, 1998, Journal of Virology.

Deleterious Effects of Hepatitis Delta Virus Replication on Host Cell Proliferation

Yu-Tseung Liu, D. Ganem, J. Pearlberg, 2001, Journal of Virology.

Immunoreceptor Tyrosine-Based Activation Motif-Dependent Signaling by Kaposi's Sarcoma-Associated Herpesvirus K1 Protein: Effects on Lytic Viral Replication

D. Ganem, D. Lukac, M. Lagunoff, 2001, Journal of Virology.

The N-terminal (pre-S2) domain of a hepatitis B virus surface glycoprotein is translocated across membranes by downstream signal sequences

V. Lingappa, D. Ganem, B. Eble, 1990, Journal of virology.

Propagation of a segment of bacteriophage λ-DNA in monkey cells after covalent linkage to a defective simian virus 40 genome

D. Ganem, A. Nussbaum, D. Davoli, 1976, Cell.

Pan-Viral Screening of Respiratory Tract Infections in Adults With and Without Asthma Reveals Unexpected Human Coronavirus and Human Rhinovirus Diversity

J. Derisi, H. Boushey, Silvi Rouskin, 2007, The Journal of infectious diseases.

RBP-J (CSL) Is Essential for Activation of the K14/vGPCR Promoter of Kaposi's Sarcoma-Associated Herpesvirus by the Lytic Switch Protein RTA

D. Ganem, Yuying Liang, 2004, Journal of Virology.

The role of envelope proteins in hepatitis B virus assembly.

D. Ganem, V. Bruss, 1991, Proceedings of the National Academy of Sciences of the United States of America.

A Kaposi's Sarcoma-Associated Herpesvirus Protein That Forms Inhibitory Complexes with Type I Interferon Receptor Subunits, Jak and STAT Proteins, and Blocks Interferon-Mediated Signal Transduction

D. Ganem, A. Page, S. A. Bisson, 2009, Journal of Virology.

Multiple Defects, Including Premature Apoptosis, Prevent Kaposi's Sarcoma-Associated Herpesvirus Replication in Murine Cells

S. Oakes, D. Ganem, K. Austgen, 2011, Journal of Virology.

A host factor that binds near the termini of hepatitis B virus pregenomic RNA

D. Ganem, S. Perri, Don Ganem, 1996, Journal of virology.

Novel N-terminal amino acid sequence required for retention of a hepatitis B virus glycoprotein in the endoplasmic reticulum

D. Ganem, K. Kuroki, R. Russnak, 1989, Molecular and cellular biology.

Induction of chemokine production by latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells.

D. Ganem, Yi-Fu Xu, 2007, The Journal of general virology.

selective from host mRNA shutoff and its implications for viral pathogenesis.

D. Ganem, 2004 .

Detection of antibodies against hepatitis B virus polymerase antigen in hepatitis B virus‐infected patients

H. Varmus, Lung-Ji Chang, D. Ganem, 1989, Hepatology.

Expression of the precore region of an avian hepatitis B virus is not required for viral replication

H. Varmus, R. Sprengel, G. Enders, 1987, Journal of virology.

Virion DNA of ground squirrel hepatitis virus: structural analysis and molecular cloning

H. Varmus, D. Ganem, L. Greenbaum, 1982, Journal of virology.

Isolation, propagation and characterization of replication requirements of reiteration mutants of Simian Virus 40.

D. Ganem, A. Nussbaum, D. Davoli, 1976, Journal of molecular biology.

The cloned genome of ground squirrel hepatitis virus is infectious in the animal.

H. Varmus, D. Ganem, C. Seeger, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Persistent hepatitis B virus following interferon alfa therapy and liver transplantation.

L. Ferrell, J. Lake, D. Ganem, 1991, Gastroenterology.

Mutational analysis of hepatitis B surface antigen particle assembly and secretion

D. Ganem, V. Bruss, 1991, Journal of virology.

Human herpesvirus 8 glycoprotein K8.1: expression, post-translational modification and localization analyzed by monoclonal antibody.

D. Ganem, L. Wu, R. Renne, 2000, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Mutations affecting hepadnavirus plus-strand DNA synthesis dissociate primer cleavage from translocation and reveal the origin of linear viral DNA

S. Staprans, D. Loeb, D. Ganem, 1991, Journal of virology.

RNAs in the Virion of Kaposi's Sarcoma-Associated Herpesvirus

D. Ganem, A. Grundhoff, J. Bechtel, 2005, Journal of Virology.

Kaposi's Sarcoma-Associated Herpesvirus ORF54/dUTPase Downregulates a Ligand for the NK Activating Receptor NKp44

D. Ganem, A. Madrid, 2012, Journal of Virology.

Kaposi ’ s Sarcoma-Associated Herpesvirus ORF 54 / dUTPase Downregulates a Ligand for the NK Activating Receptor NKp 44

D. Ganem, A. Madrid, 2012 .

Kaposi ’ s Sarcoma-Associated Herpesvirus ORF 54 / dUTPase downregulates a ligand for the NK 1 activating receptor NKp 44 2

D. Ganem, A. Madrid, 2012 .

Effects of NFkappaB activation on KSHV latency and lytic reactivation are complex and context-dependent.

D. Ganem, C. Grossmann, 2008, Virology.

Exploring the DNA Binding Interactions of the Kaposi's Sarcoma-Associated Herpesvirus Lytic Switch Protein by Selective Amplification of Bound Sequences In Vitro

D. Ganem, J. Ziegelbauer, A. Grundhoff, 2006, Journal of Virology.

Antibodies to pre-S and X determinants arise during natural infection with ground squirrel hepatitis virus

H. Varmus, D. Persing, D. Ganem, 1986, Journal of virology.

A Virus-Encoded Inhibitor That Blocks RNA Interference in Mammalian Cells

D. Ganem, C. S. Sullivan, 2005, Journal of Virology.

The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma–associated herpesvirus): Distribution of infection in KS risk groups and evidence for sexual transmission

E. Operskalski, D. Ganem, M. Busch, 1996, Nature Medicine.

Host and Viral Proteins in the Virion of Kaposi's Sarcoma-Associated Herpesvirus

D. Ganem, J. Bechtel, R. Winant, 2005, Journal of Virology.

Expression of the Open Reading Frame 74 (G-Protein-Coupled Receptor) Gene of Kaposi’s Sarcoma (KS)-Associated Herpesvirus: Implications for KS Pathogenesis

A. Haase, D. Ganem, J. Kirshner, 1999, Journal of Virology.

The prevalence of serum antibody to human herpesvirus 8 (Kaposi sarcoma-associated herpesvirus) among HIV-seropositive and high-risk HIV-seronegative women.

R. Greenblatt, P. Bacchetti, D. Ganem, 1997, JAMA.

Visualization of human herpesvirus type 8 in Kaposi's sarcoma by light and transmission electron microscopy

K. Jeang, J. Orenstein, S. Alkan, 1997, AIDS.

The biology of Kaposi's sarcoma.

D. Ganem, B. Herndier, Brian Herndier, 2001, Cancer treatment and research.

Utility of DNA Microarrays for Detection of Viruses in Acute Respiratory Tract Infections in Children

David Wang, Charles Y Chiu, Shigeo Yagi, 2008, Jornal de Pediatria.

Experimental induction of proventricular dilatation disease in cockatiels (Nymphicus hollandicus) inoculated with brain homogenates containing avian bornavirus 4

J. Derisi, D. Ganem, A. Lublin, 2009, Virology Journal.

Recovery of divergent avian bornaviruses from cases of proventricular dilatation disease: Identification of a candidate etiologic agent

J. Derisi, C. Wen, P. Skewes-Cox, 2008, Virology Journal.

Analysis of Naturally Occurring Avian Bornavirus Infection and Transmission during an Outbreak of Proventricular Dilatation Disease among Captive Psittacine Birds

J. Derisi, D. Ganem, A. Greninger, 2009, Journal of Virology.

Avian Bornavirus is Present in Many Tissues of Psittacine Birds with Histopathologic Evidence of Proventricular Dilatation Disease

J. Derisi, D. Ganem, D. Pearl, 2010, Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.

Kaposi's sarcoma-associated herpesvirus gene expression in endothelial (spindle) tumor cells

A. Haase, D. Anderson, W. Zhong, 1997, Journal of virology.

Complete genome sequence of an astrovirus identified in a domestic rabbit (Oryctolagus cuniculus) with gastroenteritis

J. Derisi, J. Ruby, D. Ganem, 2012, Virology Journal.

Lytic growth of Kaposi's sarcoma–associated herpesvirus (human herpesvirus 8) in culture

M. McGrath, W. Zhong, D. Ganem, 1996, Nature Medicine.

Identification of a previously undescribed divergent virus from the Flaviviridae family in an outbreak of equine serum hepatitis

P. Skewes-Cox, W. Zhong, D. Ganem, 2013, Proceedings of the National Academy of Sciences.

A Cellular Homolog of Hepatitis Delta Antigen: Implications for Viral Replication and Evolution

R. Brazas, D. Ganem, 1996, Science.

Multiple topogenic sequences determine the transmembrane orientation of the hepatitis B surface antigen

V. Lingappa, D. Ganem, B. Eble, 1987, Molecular and cellular biology.

Relationship between viral DNA synthesis and virion envelopment in hepatitis B viruses

J. Tavis, D. Ganem, Y. Wei, 1996, Journal of virology.

The polyalbumin hypothesis: where is it in 1989?

D. Ganem, T. Wright, 1989, Gastroenterology.

Transcriptional activation of homologous and heterologous genes by the hepatitis B virus X gene product in cells permissive for viral replication

D. Ganem, G. Simon, R. Colgrove, 1989, Journal of virology.

The pre-S domain of the large viral envelope protein determines host range in avian hepatitis B viruses.

D. Ganem, T. Ishikawa, 1995, Proceedings of the National Academy of Sciences of the United States of America.

An RNA stem-loop structure directs hepatitis B virus genomic RNA encapsidation

J. Pollack, D. Ganem, Jonathan R. Pollack, 1993, Journal of virology.

cis-acting sequences required for encapsidation of duck hepatitis B virus pregenomic RNA

J. Pollack, D. Loeb, D. Ganem, 1991, Journal of virology.

Myristylation of a duck hepatitis B virus envelope protein is essential for infectivity but not for virus assembly.

D. Ganem, V. Bruss, D. Macrae, 1991, Virology.

Effects of insertional and point mutations on the functions of the duck hepatitis B virus polymerase

H. Varmus, D. Ganem, R. Hirsch, 1990, Journal of virology.

Assembly of hepadnaviral virions and subviral particles.

D. Ganem, D Ganem, 1991, Current topics in microbiology and immunology.

An infectious retrovirus susceptible to an IFN antiviral pathway from human prostate tumors

J. Derisi, R. Silverman, E. Klein, 2007, Proceedings of the National Academy of Sciences.

Temporal Analysis of the Honey Bee Microbiome Reveals Four Novel Viruses and Seasonal Prevalence of Known Viruses, Nosema, and Crithidia

J. Derisi, R. Andino, J. Ruby, 2011, PloS one.

In Vivo Effects of Mutations in Woodchuck Hepatitis Virus Enhancer II

D. Ganem, B. Tennant, Yu Wei, 1998, Journal of Virology.

Homologous and heterologous complementation of HBV and WHV capsid and polymerase functions in RNA encapsidation.

D. Ganem, R. Ziermann, 1996, Virology.

Polymerase gene products of hepatitis B viruses are required for genomic RNA packaging as well as for reverse transcription

H. Varmus, Lung-Ji Chang, D. Ganem, 1990, Nature.

Expression of functional hepatitis B virus polymerase in yeast reveals it to be the sole viral protein required for correct initiation of reverse transcription.

J. Tavis, D. Ganem, 1993, Proceedings of the National Academy of Sciences of the United States of America.

15 Reverse Transcription Pathway of the Hepatitis B Viruses

D. Loeb, D. Ganem, 1993 .

Sequence‐independent RNA cleavages generate the primers for plus strand DNA synthesis in hepatitis B viruses: implications for other reverse transcribing elements.

D. Loeb, D. Ganem, R. Hirsch, 1991, The EMBO journal.

Biochemical and genetic evidence for the hepatitis B virus replication strategy.

H. Varmus, D. Ganem, C. Seeger, 1986, Science.

Extrahepatic hepadnavirus DNA: what does it mean?

D. Ganem, 1985, Gastroenterology.

Mapping of histone modifications in episomal HBV cccDNA uncovers an unusual chromatin organization amenable to epigenetic manipulation

Meghan M. Holdorf, W. Zhong, D. Ganem, 2015, Proceedings of the National Academy of Sciences.

Woodchuck hepatitis virus is a more efficient oncogenic agent than ground squirrel hepatitis virus in a common host

H. Varmus, L. Ferrell, D. Ganem, 1991, Journal of virology.

RNA sequences controlling the initiation and transfer of duck hepatitis B virus minus-strand DNA

J. Tavis, D. Ganem, 1995, Journal of virology.

Transmission of ground squirrel hepatitis virus to homologous and heterologous hosts

H. Varmus, D. Ganem, B. Pecha, 1985, Hepatology.

Biosynthesis of the reverse transcriptase of hepatitis B viruses involves de novo translational initiation not ribosomal frameshifting

H. Varmus, Lung-Ji Chang, D. Ganem, 1989, Nature.

Effects of mutations within and adjacent to the terminal repeats of hepatitis B virus pregenomic RNA on viral DNA synthesis

D. Ganem, S. Perri, 1997, Journal of virology.

A system for studying the selective encapsidation of hepadnavirus RNA

D. Ganem, J. Lavine, R. Hirsch, 1989, Journal of virology.

5'-terminal sequences influence the segregation of ground squirrel hepatitis virus RNAs into polyribosomes and viral core particles

H. Varmus, G. Enders, D. Ganem, 1987, Journal of virology.

Epitope mapping of the PreS1 domain of the hepatitis B virus large surface protein.

D. Ganem, L. Mimms, K. Kuroki, 1990, Virology.

A frameshift mutation in the pre-S region of the human hepatitis B virus genome allows production of surface antigen particles but eliminates binding to polymerized albumin.

H. Varmus, D. Persing, D. Ganem, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Cellular factors controlling the activity of woodchuck hepatitis virus enhancer II

D. Ganem, K. Ueda, Y. Wei, 1996, Journal of virology.

Apoptosis is induced by N-myc expression in hepatocytes, a frequent event in hepadnavirus oncogenesis, and is blocked by insulin-like growth factor II

D. Ganem, K. Ueda, K. Ueda, 1996, Journal of virology.

Differential activation of myc gene family members in hepatic carcinogenesis by closely related hepatitis B viruses

D. Ganem, B. Tennant, C. Seeger, 1993, Molecular and cellular biology.

Phenotypic mixing between different hepadnavirus nucleocapsid proteins reveals C protein dimerization to be cis preferential

S. Zhou, D. Ganem, D. Standring, 1994, Journal of virology.

A combined computational and microarray-based approach identifies novel microRNAs encoded by human gamma-herpesviruses.

Adam Grundhoff, D. Ganem, A. Grundhoff, 2006, RNA.

MicroRNAs and viral infection.

D. Ganem, Christopher S Sullivan, Don Ganem, 2005, Molecular cell.

Upstream sequences and cap proximity in the regulation of polyadenylation in ground squirrel hepatitis virus

J. Cherrington, D. Ganem, R. Russnak, 1992, Journal of virology.

Murine Polyomavirus encodes a microRNA that cleaves early RNA transcripts but is not essential for experimental infection.

D. Ganem, T. Benjamin, A. Grundhoff, 2009, Virology.

Tandem array–based expression screens identify host mRNA targets of virus-encoded microRNAs

D. Ganem, J. Ziegelbauer, Christopher S Sullivan, 2009, Nature Genetics.

Expression and function of microRNAs in viruses great and small.

R. Treisman, J. Pipas, D. Ganem, 2006, Cold Spring Harbor symposia on quantitative biology.

Regulation of KSHV lytic switch protein expression by a virus-encoded microRNA: an evolutionary adaptation that fine-tunes lytic reactivation.

D. Ganem, Priya Bellare, 2009, Cell host & microbe.

SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells

James M. Pipas, J. Pipas, D. Ganem, 2005, Nature.

SV 40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells

J. Pipas, D. Ganem, A. Grundhoff, 2005 .

Making Sense of Antisense: Seemingly Noncoding RNAs Antisense to the Master Regulator of Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication Do Not Regulate That Transcript but Serve as mRNAs Encoding Small Peptides

D. Ganem, Yiyang Xu, 2010, Journal of Virology.

Lytic but not latent infection by Kaposi's sarcoma-associated herpesvirus requires host CSL protein, the mediator of Notch signaling

D. Ganem, Yuying Liang, 2003, Proceedings of the National Academy of Sciences of the United States of America.

The lytic switch protein of KSHV activates gene expression via functional interaction with RBP-Jkappa (CSL), the target of the Notch signaling pathway.

D. Ganem, Yuying Liang, Jean Chang, 2002, Genes & development.

KSHV 2.0: A Comprehensive Annotation of the Kaposi's Sarcoma-Associated Herpesvirus Genome Using Next-Generation Sequencing Reveals Novel Genomic and Functional Features

J. Weissman, Meghan M. Holdorf, Noam Stern-Ginossar, 2014, PLoS pathogens.

Kaposi's sarcoma‐derived cell line SLK is not of endothelial origin, but is a contaminant from a known renal carcinoma cell line

D. Ganem, W. Dirks, M. Stürzl, 2013, International journal of cancer.

Infection of primary human tonsillar lymphoid cells by KSHV reveals frequent but abortive infection of T cells.

D. Ganem, J. Myoung, 2011, Virology.

Array-Based Transcript Profiling and Limiting-Dilution Reverse Transcription-PCR Analysis Identify Additional Latent Genes in Kaposi's Sarcoma-Associated Herpesvirus

D. Ganem, S. Chandriani, 2010, Journal of Virology.

Host Transcript Accumulation during Lytic KSHV Infection Reveals Several Classes of Host Responses

D. Ganem, S. Chandriani, 2007, PloS one.

KSHV infection and the pathogenesis of Kaposi's sarcoma.

D. Ganem, Don Ganem, 2006, Annual review of pathology.

Host Range of Kaposi's Sarcoma-Associated Herpesvirus in Cultured Cells

D. Ganem, Yuying Liang, J. Bechtel, 2003, Journal of Virology.

Modulation of host gene expression by the constitutively active G protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus.

J. Derisi, D. Ganem, A. Polson, 2002, Cancer research.

De Novo Infection and Serial Transmission of Kaposi's Sarcoma-Associated Herpesvirus in Cultured Endothelial Cells

M. McMahon, E. Venetsanakos, D. Ganem, 2002, Journal of Virology.

Kaposi's Sarcoma-Associated Herpesvirus K-bZIP Protein Is Phosphorylated by Cyclin-Dependent Kinases

A. Burlingame, Lan Huang, D. Morgan, 2001, Journal of Virology.

Mechanisms Governing Expression of the v-FLIP Gene of Kaposi's Sarcoma-Associated Herpesvirus

D. Ganem, A. Grundhoff, 2001, Journal of Virology.

Evidence for concurrent epidemics of human herpesvirus 8 and human immunodeficiency virus type 1 in US homosexual men: rates, risk factors, and relationship to Kaposi's sarcoma.

J. Goedert, P. Rosenberg, T. O'Brien, 1999, The Journal of infectious diseases.

A Complex Translational Program Generates Multiple Novel Proteins from the Latently Expressed Kaposin (K12) Locus of Kaposi’s Sarcoma-Associated Herpesvirus

Lijun Wu, Bagher Forghani, W. Zhong, 1999, Journal of Virology.

Sexual transmission and the natural history of human herpesvirus 8 infection.

Jeffrey N. Martin, D. Osmond, D. Ganem, 1998, The New England journal of medicine.

KSHV and Kaposi's Sarcoma: The End of the Beginning?

D. Ganem, 1997, Cell.

The structure and coding organization of the genomic termini of Kaposi's sarcoma-associated herpesvirus.

D. Ganem, M. Lagunoff, 1997, Virology.

The protease and the assembly protein of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8)

C. Craik, A. Unal, D. Ganem, 1997, Journal of virology.

Characterization of ribonucleoprotein complexes containing an abundant polyadenylated nuclear RNA encoded by Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8)

W. Zhong, D. Ganem, 1997, Journal of virology.

Viral latency and its regulation: lessons from the gamma-herpesviruses.

D. Ganem, S. Speck, 2010, Cell host & microbe.

Kaposi's sarcoma-associated herpesvirus encodes two proteins that block cell surface display of MHC class I chains by enhancing their endocytosis.

D. Ganem, L. Coscoy, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Viral microRNA target allows insight into the role of translation in governing microRNA target accessibility

D. Ganem, Horng-Ru Lin, 2011, Proceedings of the National Academy of Sciences.

MicroRNAs of Kaposi's sarcoma-associated herpes virus.

D. Ganem, J. Ziegelbauer, 2008, Seminars in cancer biology.

Identification of a Novel Gammaretrovirus in Prostate Tumors of Patients Homozygous for R462Q RNASEL Variant

J. Derisi, R. Silverman, G. Casey, 2006, PLoS pathogens.

Messenger RNA turnover and its regulation in herpesviral infection.

D. Ganem, B. Glaunsinger, 2006, Advances in virus research.

A Genome-wide CRISPR Screen Identifies ZCCHC14 as a Host Factor Required for Hepatitis B Surface Antigen Production.

Meghan M. Holdorf, P. Feucht, D. Ganem, 2019, Cell Reports.

A genome-wide CRISPR screen identifies ZCCHC14 as a host factor required for hepatitis B surface antigen production

Meghan M. Holdorf, P. Feucht, D. Ganem, 2019, bioRxiv.

Genetic studies of the lac repressor. II. Fine structure deletion map of the lacI gene, and its correlation with the physical map.

J. Miller, Jeffrey H. Miller, D. Ganem, 1977, Journal of molecular biology.

A block to the intracellular transport and assembly of hepatitis B surface antigen polypeptides in Xenopus oocytes.

V. Lingappa, D. Ganem, K. Simon, 1988, Virology.

Regulation of polyadenylation in human immunodeficiency virus (HIV): contributions of promoter proximity and upstream sequences.

J. Cherrington, D. Ganem, Don Ganem, 1992, The EMBO journal.

Virion DNA ofGroundSquirrel Hepatitis Virus: Structural Analysis andMolecular Cloning

D. Ganem, 1982 .

Modulation of Cellular and Viral Gene Expression by the Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus

P. Brown, C. Barry, D. Dittmer, 2001, Journal of Virology.

Restricted expression of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genes in Kaposi sarcoma.

W. Zhong, H. Wang, D. Ganem, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Infection of Lymphoblastoid Cell Lines by Kaposi's Sarcoma-Associated Herpesvirus: Critical Role of Cell-Associated Virus

D. Ganem, J. Myoung, 2011, Journal of Virology.

Inefficient Codon Usage Impairs mRNA Accumulation: the Case of the v-FLIP Gene of Kaposi's Sarcoma-Associated Herpesvirus

D. Ganem, Priya Bellare, Andrew Dufresne, 2015, Journal of Virology.

The Lytic Transcriptome of Kaposi's Sarcoma-Associated Herpesvirus Reveals Extensive Transcription of Noncoding Regions, Including Regions Antisense to Important Genes

D. Ganem, Yiyang Xu, S. Chandriani, 2010, Journal of Virology.

Limited Transmission of Kaposi’s Sarcoma-Associated Herpesvirus in Cultured Cells

D. Ganem, D. Whitby, R. Renne, 1998, Journal of Virology.

Human herpesvirus 8 and the biology of Kaposi's sarcoma

D. Ganem, 1996 .

Inflammatory cytokines and the reactivation of Kaposi's sarcoma-associated herpesvirus lytic replication.

D. Dittmer, D. Ganem, R. Renne, 2000, Virology.

Identification of cardioviruses related to Theiler's murine encephalomyelitis virus in human infections

J. Derisi, D. Ganem, C. Glaser, 2008, Proceedings of the National Academy of Sciences.

At a Glance Commentary

J. Derisi, H. Collard, H. Boushey, 2022 .

Complete genome sequence of an astrovirus identified in a domestic rabbit (Oryctolagus cuniculus) with gastroenteritis

J. Derisi, J. Ruby, D. Ganem, 2021 .

Title Complete genome sequence of an astrovirus identified in a domestic rabbit ( Oryctolagus cuniculus ) with gastroenteritis Permalink

J. Derisi, J. Ruby, D. Ganem, 2012 .

Diagnosis of a Critical Respiratory Illness Caused by Human Metapneumovirus by Use of a Pan-Virus Microarray

Ash A. Alizadeh, Ash A Alizadeh, Joseph L DeRisi, 2007, Journal of Clinical Microbiology.

Microarray Detection of Human Parainfluenzavirus 4 Infection Associated with Respiratory Failure in an Immunocompetent Adult

Joseph L. DeRisi, Jason D. Merker, Charles Y. Chiu, 2006, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Short ReviewMicroRNAs and Viral Infection

D. Ganem, C. S. Sullivan, 2005 .

Cloning and characterization of the RNA polymerase alpha-subunit operon of Chlamydia trachomatis

M. Tan, J. Engel, D. Ganem, 1993, Journal of bacteriology.

Chlamydiapolymerase alpha-subunit operon of Cloning and characterization of the RNA

D. Ganem, R. Grant, R. Klein, 2022 .

Heat shock response of murine Chlamydia trachomatis

J. Pollack, J. Engel, D. Ganem, 1990, Journal of bacteriology.

Functional Organization of MIR2, a Novel Viral Regulator of Selective Endocytosis*

D. Ganem, L. Coscoy, D. J. Sanchez, 2002, The Journal of Biological Chemistry.

A novel class of herpesvirus-encoded membrane-bound E3 ubiquitin ligases regulates endocytosis of proteins involved in immune recognition

D. Ganem, L. Coscoy, D. J. Sanchez, 2001, The Journal of cell biology.