G. S. Shelness

发表

A novel role for ABCA1-generated large pre-β migrating nascent HDL in the regulation of hepatic VLDL triglyceride secretion[S]

Soonkyu Chung, A. Gebre, Jeongmin Seo, 2010, Journal of Lipid Research.

A novel role for ABCA1-generated large pre-beta migrating nascent HDL in the regulation of hepatic VLDL triglyceride secretion.

Soonkyu Chung, A. Gebre, Jeongmin Seo, 2010, Journal of lipid research.

The constitutive lipid droplet protein PLIN2 regulates autophagy in liver

P. Saha, G. S. Shelness, B. Chang, 2017, Autophagy.

Very-low-density lipoprotein assembly and secretion

G. S. Shelness, J. Sellers, 2001, Current opinion in lipidology.

ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1

Tom T. Chen, L. Carmel, M. Iruela-Arispe, 2012, Nature Medicine.

The NH2-terminal Region of Apolipoprotein B Is Sufficient for Lipoprotein Association with Glycosaminoglycans*

L. Paka, G. S. Shelness, S. Pillarisetti, 1998, The Journal of Biological Chemistry.

CGI-58 facilitates the mobilization of cytoplasmic triglyceride for lipoprotein secretion in hepatoma cellss⃞s⃞ The online version of this article (available at http://www.jlr.org) contains supplementary data in the form of 2 figures. Published, JLR Papers in Press, July 30, 2007.

J. M. Brown, Soonkyu Chung, G. S. Shelness, 2007, Journal of Lipid Research.

Isolation and characterization of a cDNA clone specific for avian viteDogenin II

G. S. Shelness, P. Ostapchuk, A. Protter, 2005 .

Apolipoprotein M expression increases the size of nascent preβ HDL formed by ATP binding cassette transporter A1

Amanda L. Brown, A. Gebre, Jeongmin Seo, 2010, Journal of Lipid Research.

Quality control in the apoA-I secretory pathway: deletion of apoA-I helix 6 leads to the formation of cytosolic phospholipid inclusions.

M. Willingham, G. S. Shelness, Michael J. Thomas, 2004, Journal of lipid research.

ApoA-I secretion from HepG2 cells: evidence for the secretion of both lipid-poor apoA-I and intracellularly assembled nascent HDL.

G. S. Shelness, J. Parks, J. W. Chisholm, 2002, Journal of lipid research.

Biogenesis of apolipoprotein A-V and its impact on VLDL triglyceride secretion[S]

G. S. Shelness, Melissa A. Fabritius, R. Weinberg, 2011, Journal of Lipid Research.

Identification of the Lipoprotein Initiating Domain of Apolipoprotein B*

G. S. Shelness, J. Parks, R. Weinberg, 2003, Journal of Biological Chemistry.

Monounsaturated fatty acids and atherosclerosis: Opposing views from epidemiology and experimental animal models

G. S. Shelness, L. Rudel, J. Mark Brown, 2007, Current atherosclerosis reports.

A role for the pregnane X receptor in high-density lipoprotein metabolism.

G. S. Shelness, L. Rudel, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Localization of APOL1 protein and mRNA in the human kidney: nondiseased tissue, primary cells, and immortalized cell lines.

B. Freedman, M. Kretzler, A. Hemal, 2015, Journal of the American Society of Nephrology : JASN.

Characterization of circulating APOL1 protein complexes in African Americans[S]

B. Freedman, G. Hawkins, Dongmei Cheng, 2016, Journal of Lipid Research.

Biogenesis and cytotoxicity of APOL1 renal risk variant proteins in hepatocytes and hepatoma cells

B. Freedman, Dongmei Cheng, G. S. Shelness, 2015, Journal of Lipid Research.

Hepatic ABCA1 deficiency is associated with delayed apolipoprotein B secretory trafficking and augmented VLDL triglyceride secretion.

Soonkyu Chung, G. S. Shelness, J. Parks, 2017, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Microsomal Triglyceride Transfer Protein Promotes the Secretion of Xenopus laevis Vitellogenin A1*

G. S. Shelness, J. Sellers, Daniel R Schoenberg, 2005, Journal of Biological Chemistry.

Phospholipid Transfer Activity of Microsomal Triacylglycerol Transfer Protein Is Sufficient for the Assembly and Secretion of Apolipoprotein B Lipoproteins*

G. S. Shelness, M. Hussain, P. Rava, 2006, Journal of Biological Chemistry.

Hepatic Apolipoprotein M (ApoM) Overexpression Stimulates Formation of Larger ApoM/Sphingosine 1-Phosphate-enriched Plasma High Density Lipoprotein*

S. Spiegel, A. Gebre, Jeongmin Seo, 2013, The Journal of Biological Chemistry.

Efficient glycosylation site utilization by intracellular apolipoprotein B. Implications for proteasomal degradation.

G. S. Shelness, X. F. Huang, X. F. Huang, 1999, Journal of lipid research.

Posttranslational Regulation of Acid Sphingomyelinase in Niemann-Pick Type C1 Fibroblasts and Free Cholesterol-enriched Chinese Hamster Ovary Cells*

G. S. Shelness, J. W. Reagan, Melissa L. Hubbert, 2000, The Journal of Biological Chemistry.

Hepatic ABCA1 and VLDL triglyceride production.

Soonkyu Chung, G. S. Shelness, J. Parks, 2012, Biochimica et biophysica acta.

APOLIPOPROTEIN B: mRNA editing, lipoprotein assembly, and presecretory degradation.

N. Davidson, G. S. Shelness, 2000, Annual review of nutrition.

Apolipoprotein B in the rough endoplasmic reticulum: translation, translocation and the initiation of lipoprotein assembly.

G. S. Shelness, J. A. DeLozier, M. F. Ingram, 1999, The Journal of nutrition.

Amino Acids 430–570 in Apolipoprotein B Are Critical for Its Binding to Microsomal Triglyceride Transfer Protein*

G. S. Shelness, M. Hussain, A. Bakillah, 1998, The Journal of Biological Chemistry.

Role of intramolecular disulfide bond formation in the assembly and secretion of apolipoprotein B-100-containing lipoproteins.

G. S. Shelness, J. Thornburg, 1996, Journal of lipid research.

ApoA-IV modulates the secretory trafficking of apoB and the size of triglyceride-rich lipoproteins

J. W. Gallagher, G. S. Shelness, Melissa A. Fabritius, 2012, Journal of Lipid Research.

Evolution and mechanism of apolipoprotein B-containing lipoprotein assembly

G. S. Shelness, Aubrey S. Ledford, 2005, Current opinion in lipidology.

HEPATIC ATP-BINDING CASSETTE TRANSPORTER A 1 AND TRIGLYCERIDE METABOLISM : IN-VITRO STUDIES

Soonkyu Chung, G. S. Shelness, J. Parks, 2016 .

Hepatic ABC transporters and triglyceride metabolism

Soonkyu Chung, G. S. Shelness, J. Parks, 2012, Current opinion in lipidology.

Folding of the Amino-terminal Domain of Apolipoprotein B Initiates Microsomal Triglyceride Transfer Protein-dependent Lipid Transfer to Nascent Very Low Density Lipoprotein*

G. S. Shelness, M. F. Ingram, 1997, The Journal of Biological Chemistry.

25 – Sequence and Structural Elements Associated with the Degradation of Apolipoprotein II Messenger RNA

Sheng-Ping L. Hwang, G. S. Shelness, D. Gordon, 1987 .

Very Low Density Lipoprotein Assembly Is Required for cAMP-responsive Element-binding Protein H Processing and Hepatic Apolipoprotein A-IV Expression*

Dongmei Cheng, G. S. Shelness, J. Parks, 2016, The Journal of Biological Chemistry.

Apolipoprotein A-IV Expression in Mouse Liver Enhances Triglyceride Secretion and Reduces Hepatic Lipid Content by Promoting Very Low Density Lipoprotein Particle Expansion

Dongmei Cheng, G. S. Shelness, R. Weinberg, 2013, Arteriosclerosis, thrombosis, and vascular biology.

Measurement of apolipoprotein mRNA by DNA-excess solution hybridization with single-stranded probes.

G. S. Shelness, D. Williams, T. Newman, 1986, Methods in enzymology.

Uncleaved ApoM Signal Peptide Is Required for Formation of Large ApoM/Sphingosine 1-Phosphate (S1P)-enriched HDL Particles*

S. Spiegel, Dongmei Cheng, A. Gebre, 2015, The Journal of Biological Chemistry.

Phospholipid transfer activity of microsomal triglyceride transfer protein produces apolipoprotein B and reduces hepatosteatosis while maintaining low plasma lipids in mice

S. Zeissig, D. Curiel, Minghui Wang, 2012, Hepatology.

Heritable, diet-induced hyperlipidemia in California mice (Peromyscus californicus) is due to increased hepatic secretion of very low density lipoprotein triacylglycerol.

L. Krugner-Higby, G. S. Shelness, A. Holler, 2006, Comparative medicine.

Uncleaved apoM signal peptide is required for formation of large apoM/S1P-enriched HDL particles ‡

S. Spiegel, Dongmei Cheng, A. Gebre, 2015 .

cDNA-derived primary structure of the glycoprotein component of canine microsomal signal peptidase complex.

G. Blobel, G. S. Shelness, Y. Kanwar, 1988, The Journal of biological chemistry.

Identification of Cysteine Pairs within the Amino-terminal 5% of Apolipoprotein B Essential for Hepatic Lipoprotein Assembly and Secretion*

G. S. Shelness, X. F. Huang, X. F. Huang, 1997, The Journal of Biological Chemistry.

ACAT2 stimulates cholesteryl ester secretion in apoB-containing lipoproteins Published, JLR Papers in Press, April 16, 2007.

G. S. Shelness, L. Rudel, R. Temel, 2007, Journal of Lipid Research.

Vesicle-binding properties of wild-type and cysteine mutant forms of alpha(1) domain of apolipoprotein B.

G. S. Shelness, J. Parks, J. A. DeLozier, 2001, Journal of lipid research.

Symposium : Assembly and Physiology of Apolipoprotein B – Containing Lipoproteins : Not Just for Heart Disease Anymore ! Apolipoprotein B in the Rough Endoplasmic Reticulum : Translation , Translocation and the Initiation of Lipoprotein Assembly 1

G. S. Shelness, J. A. DeLozier, M. F. Ingram, 1999 .

High Affinity Binding between Lipoprotein Lipase and Lipoproteins Involves Multiple Ionic and Hydrophobic Interactions, Does Not Require Enzyme Activity, and Is Modulated by Glycosaminoglycans*

G. S. Shelness, I. Goldberg, M. Hussain, 2000, The Journal of Biological Chemistry.

Membrane topology and biogenesis of eukaryotic signal peptidase.

C. Nicchitta, G. S. Shelness, L. Lin, 1993, The Journal of biological chemistry.

Targeted Deletion of Hepatocyte ABCA1 Leads to Very Low Density Lipoprotein Triglyceride Overproduction and Low Density Lipoprotein Hypercatabolism*

M. Hayden, N. Maeda, Soonkyu Chung, 2010, The Journal of Biological Chemistry.

apoA-IV tagged with the ER retention signal KDEL perturbs the intracellular trafficking and secretion of apoB Published, JLR Papers in Press, July 16, 2004. DOI 10.1194/jlr.M400188-JLR200

J. W. Gallagher, G. S. Shelness, R. Weinberg, 2004, Journal of Lipid Research.

Dynamic interfacial properties of human apolipoproteins A-IV and B-17 at the air/water and oil/water interface.

G. S. Shelness, R. Weinberg, J. A. DeLozier, 2000, Journal of lipid research.

Overexpression of Apolipoprotein A-IV Enhances Lipid Secretion in IPEC-1 Cells by Increasing Chylomicron Size*

J. W. Gallagher, G. S. Shelness, G. Morris, 2006, Journal of Biological Chemistry.

The gas chromatographic and mass spectrometric behavior of 2‐amino‐1‐iodo‐3‐phenylpropane (iodoamphetamine)

G. S. Shelness, R. T. Coutts, N. Shaath, 1980 .

Stage- and ribosome-specific alterations in nascent chain-Sec61p interactions accompany translocation across the ER membrane

C. Nicchitta, R. Haynes, G. S. Shelness, 1995, The Journal of cell biology.

Isolation and characterization of a cDNA clone specific for avian vitellogenin II.

G. S. Shelness, P. Ostapchuk, D. Williams, 1982, Nucleic acids research.

Identification of a Form of Acyl-CoA:Cholesterol Acyltransferase Specific to Liver and Intestine in Nonhuman Primates*

G. S. Shelness, L. Rudel, R A Anderson, 1998, The Journal of Biological Chemistry.

ACAT1 and ACAT2 membrane topology segregates a serine residue essential for activity to opposite sides of the endoplasmic reticulum membrane.

M. Davis, R. G. Lee, G. S. Shelness, 2000, Molecular biology of the cell.

Alternative splicing attenuates transgenic expression directed by the apolipoprotein E promoter-enhancer based expression vector pLIV11[S]

Dongmei Cheng, G. S. Shelness, J. Parks, 2010, Journal of Lipid Research.

Apolipoprotein II messenger RNA. Transcriptional and splicing heterogeneity yields six 5'-untranslated leader sequences.

G. S. Shelness, D. Williams, 1984, Journal of Biological Chemistry.

Two subunits of the canine signal peptidase complex are homologous to yeast SEC11 protein.

G. Blobel, G. S. Shelness, 1990, The Journal of biological chemistry.

Structure and Interfacial Properties of Human Apolipoprotein A-V*

J. W. Gallagher, G. S. Shelness, R. Ryan, 2003, Journal of Biological Chemistry.

Cloning and Characterization of Cyclooxygenase-1b (Putative Cyclooxygenase-3) in Rat

G. S. Shelness, D. Busija, B. Kis, 2005, Journal of Pharmacology and Experimental Therapeutics.

Estrogen-induced destabilization of yolk precursor protein mRNAs in avian liver.

G. S. Shelness, D. Gordon, D. Williams, 1988, The Journal of biological chemistry.

Secondary structure analysis of apolipoprotein II mRNA using enzymatic probes and reverse transcriptase. Evaluation of primer extension for high resolution structure mapping of mRNA.

G. S. Shelness, D. Williams, 1985, The Journal of biological chemistry.

Predicted structures of apolipoprotein II mRNA constrained by nuclease and dimethyl sulfate reactivity: stable secondary structures occur predominantly in local domains via intraexonic base pairing.

G. S. Shelness, D. Williams, M. Eisenberg, 1989, The Journal of biological chemistry.

Identification of a Novel Isoform of Microsomal Triglyceride Transfer Protein*

A. Ham, G. S. Shelness, P. Mohler, 2007, Journal of Biological Chemistry.

Cholesterol esters and atherosclerosis–a game of ACAT and mouse

G. S. Shelness, L. Rudel, 2000, Nature Medicine.

Lipoprotein assembly capacity of the mammary tumor-derived cell line C127 is due to the expression of functional microsomal triglyceride transfer protein.

G. S. Shelness, J. Sellers, 2001, Journal of lipid research.

Current biology of MTP: implications for selective inhibition.

C. Shoulders, G. S. Shelness, 2005, Current topics in medicinal chemistry.

Self-association and Lipid Binding Properties of the Lipoprotein Initiating Domain of Apolipoprotein B*

G. S. Shelness, R. Hantgan, R. Weinberg, 2006, Journal of Biological Chemistry.

Structural and dynamic interfacial properties of the lipoprotein initiating domain of apolipoprotein B Structural and dynamic interfacial properties of the lipoprotein initiating domain of apolipoprotein

G. S. Shelness, R. Weinberg, V. A. Cook, 2008 .

Apolipoprotein B-100 destined for lipoprotein assembly and intracellular degradation undergoes efficient translocation across the endoplasmic reticulum membrane.

G. S. Shelness, M. F. Ingram, 1996, Journal of lipid research.

Apolipoprotein B48-membrane interactions. Absence of transmembrane localization in nonhepatic cells.

G. S. Shelness, M. F. Ingram, K. C. Morris-Rogers, 1994, The Journal of biological chemistry.

A subunit of mammalian signal peptidase is homologous to yeast SEC11 protein.

G. Blobel, G. S. Shelness, G. Greenburg, 1989, The Journal of biological chemistry.

A Drosophila Microsomal Triglyceride Transfer Protein Homolog Promotes the Assembly and Secretion of Human Apolipoprotein B

G. S. Shelness, M. Hussain, J. Sellers, 2003, Journal of Biological Chemistry.