J. Bass

发表

Leptin Deficiency and Beta-Cell Dysfunction Underlie Type 2 Diabetes in Compound Akt Knockout Mice

L. Philipson, N. Hay, K. Coleman, 2009, Molecular and Cellular Biology.

Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD+ Biosynthesis

J. Takahashi, J. Bass, S. Imai, 2009, Science.

Circadian Integration of Metabolism and Energetics

Joseph S. Takahashi, J. Takahashi, J. Bass, 2010, Science.

Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice

Fred W. Turek, Erin L. McDearmon, Joseph S. Takahashi, 2005, Science.

Circadian topology of metabolism

J. Bass, Joseph Bass, 2012, Nature.

Circadian clocks and metabolism.

J. Bass, E. Maury, K. M. Ramsey, 2013, Handbook of experimental pharmacology.

Nutrient sensing and the circadian clock

J. Bass, K. M. Ramsey, B. Marcheva, 2012, Trends in Endocrinology & Metabolism.

Circadian Timing of Food Intake Contributes to Weight Gain

F. Turek, M. Vitaterna, J. Bass, 2009, Obesity.

The Meter of Metabolism

Joseph S. Takahashi, J. Takahashi, J. Bass, 2008, Cell.

Ghrelin-immunopositive hypothalamic neurons tie the circadian clock and visual system to the lateral hypothalamic arousal center.

J. Takahashi, Y. Li, M. Dietrich, 2012, Molecular metabolism.

Power and Population Structure

A. Su, J. Takahashi, T. Wiltshire, 2007 .

Familial British Dementia: Expression and Metabolism of BRI

D. Steiner, J. Bass, S. H. Kim, 2000, Annals of the New York Academy of Sciences.

Mutational analysis of allosteric activation and inhibition of glucokinase.

C. Stanley, J. Vanderkooi, J. Bass, 2011, The Biochemical journal.

Folding of Insulin Receptor Monomers Is Facilitated by the Molecular Chaperones Calnexin and Calreticulin and Impaired by Rapid Dimerization

D. Steiner, J. Bass, Y. Argon, 1998, The Journal of cell biology.

You are when you eat: on circadian timing and energy balance.

J. Bass, J. Cedernaes, 2021, The Journal of clinical investigation.

The circadian clock system’s influence in health and disease

J. Bass, 2017, Genome Medicine.

A day in the life of chromatin: how enhancer-promoter loops shape daily behavior.

J. Bass, Benjamin J Weidemann, K. M. Ramsey, 2018, Genes & development.

Circadian Clock Interaction with HIF1α Mediates Oxygenic Metabolism and Anaerobic Glycolysis in Skeletal Muscle.

J. Bass, Yumiko Kobayashi, K. M. Ramsey, 2017, Cell metabolism.

Furin-mediated processing in the early secretory pathway: sequential cleavage and degradation of misfolded insulin receptors.

C. Turck, D. Steiner, J. Bass, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Circadian Mechanisms in Bioenergetics and Cell Metabolism

J. Bass, 2016 .

Calreticulin and Hsp90 stabilize the human insulin receptor and promote its mobility in the endoplasmic reticulum

J. Bass, R. R. Ramos, Andrea J Swanson, 2007, Proceedings of the National Academy of Sciences.

mTOR regulation of metabolism limits LPS-induced monocyte inflammatory and procoagulant responses

J. Brenchley, R. D’Aquila, H. Taylor, 2022, Communications Biology.

Clock Genes and Metabolic Regulation

A. Kohsaka, J. Bass, 2009 .

Time-restricted feeding mitigates obesity through adipocyte thermogenesis

J. Bass, Yumiko Kobayashi, Mengle Shao, 2022, Science.

Circadian Clock NAD+ Cycle Drives Mitochondrial Oxidative Metabolism in Mice

J. Denu, N. Chandel, O. Ilkayeva, 2013, Science.

A window in time for β-cell regeneration

J. Bass, Benjamin J Weidemann, 2020, Genes & development.

Transcriptional Basis for Rhythmic Control of Hunger and Metabolism within the AgRP Neuron.

J. Takahashi, R. Ahima, Xiaozhong Wang, 2019, Cell metabolism.

Medicine in the Fourth Dimension.

Steven A. Brown, A. Loudon, J. Takahashi, 2019, Cell metabolism.

Gene Set Enrichment in eQTL Data Identifies Novel Annotations and Pathway Regulators

Serge Batalov, Andrew I. Su, Jie Zhang, 2008, PLoS genetics.

Genomewide Association Analysis in Diverse Inbred Mice: Power and Population Structure

Serge Batalov, Andrew I. Su, Chunlei Wu, 2007, Genetics.

P2Y1 purinergic receptor identified as a diabetes target in a small-molecule screen to reverse circadian β-cell failure

P. MacDonald, J. E. Manning Fox, J. Bass, 2022, eLife.

Defining a Novel Role for the Pdx1 Transcription Factor in Islet β-Cell Maturation and Proliferation During Weaning

R. Stein, C. Wright, M. Magnuson, 2017, Diabetes.

Pharmacologic rescue of circadian β-cell failure through P2Y1 purinergic receptor identified by small-molecule screen

P. MacDonald, J. Bass, J. M. Fox, 2021 .

Circadian regulation of cellular physiology.

J. Bass, K. M. Ramsey, B. Marcheva, 2015, Methods in enzymology.

Circadian measurements of sirtuin biology.

J. Bass, H. Hong, K. M. Ramsey, 2013, Methods in molecular biology.

Circadian disruption and metabolic disease: findings from animal models.

F. Turek, J. Bass, K. M. Ramsey, 2010, Best practice & research. Clinical endocrinology & metabolism.

NAD+ Controls Circadian Reprogramming through PER2 Nuclear Translocation to Counter Aging.

Mark S. Schmidt, C. Brenner, J. Bass, 2020, Molecular cell.

Circadian Mechanisms in Medicine.

R. Allada, J. Bass, 2021, The New England journal of medicine.

ROS‐Mediated PARP Activity Undermines Mitochondrial Function After Permeability Transition Pore Opening During Myocardial Ischemia–Reperfusion

J. Bass, P. Schumacker, Jacqueline M. Schriewer, 2013, Journal of the American Heart Association.

Circadian clocks in fuel harvesting and energy homeostasis.

J. Bass, K. M. Ramsey, 2011, Cold Spring Harbor symposia on quantitative biology.

Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia

D. Steiner, J. Bass, S. Sisodia, 1999, Nature Neuroscience.

Circadian Rhythms and Metabolic Syndrome: From Experimental Genetics to Human Disease

Kathryn Moynihan Ramsey, J. Bass, E. Maury, 2010, Circulation research.

Circadian rhythms, sleep, and metabolism.

Kathryn Moynihan Ramsey, J. Bass, K. M. Ramsey, 2011, The Journal of clinical investigation.

A role for alternative splicing in circadian control of exocytosis and glucose homeostasis

Gene W. Yeo, P. MacDonald, J. Bass, 2020, Genes & development.

Cryptochromes-Mediated Inhibition of the CRL4Cop1-Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism

M. Pagano, J. Bass, Luca Rizzini, 2019, Current Biology.

Cryptochromes-mediated Inhibition of the CRL4Cop1- Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism

M. Pagano, J. Bass, Luca Rizzini, 2019, bioRxiv.

Obeying the clock yields benefits for metabolism

J. Bass, K. M. Ramsey, 2009, Proceedings of the National Academy of Sciences.

Repair of diverse diabetic defects of β‐cells in man and mouse by pharmacological glucokinase activation

J. Bass, F. Matschinsky, N. Doliba, 2012, Diabetes, obesity & metabolism.

Gamma-protocadherins regulate the functional integrity of hypothalamic feeding circuitry in mice.

Xiaozhong Wang, A. Kohsaka, J. Bass, 2010, Developmental biology.

Disruption of the Clock Components CLOCK and BMAL 1 Leads to Hypoinsulinemia and Diabetes

Joseph S. Takahashi, Christopher A. Bradfield, Lellean JeBailey, 2012 .

Pancreatic β cell enhancers regulate rhythmic transcription of genes controlling insulin secretion

Alan L. Hutchison, G. Barish, A. Dinner, 2015, Science.

Alanine Scanning Mutagenesis of Insulin*

Claus Kristensen, Svend Havelund, D. Steiner, 1997, The Journal of Biological Chemistry.

High-fat diet disrupts behavioral and molecular circadian rhythms in mice.

Kathryn Moynihan Ramsey, F. Turek, A. Kohsaka, 2007, Cell metabolism.

Klf15 orchestrates circadian nitrogen homeostasis.

Saptarsi M. Haldar, F. Scheer, Hyoung-Gon Lee, 2012, Cell metabolism.

Clock Genes and Energy Metabolism

J. Bass, H. Hong, K. M. Ramsey, 2012 .

Circadian genes and insulin exocytosis

J. Bass, K. M. Ramsey, B. Marcheva, 2011, Cellular logistics.

Sleep, Circadian Rhythms and Metabolism

J. Bass, E. Maury, K. M. Ramsey, 2011 .

High glucose, no cry

J. Bass, 2010, Nature Medicine.

Sleep and circadian rhythms: Key components in the regulation of energy metabolism

F. Turek, A. Kohsaka, J. Bass, 2008, FEBS letters.

The clockwork of metabolism.

A. Kohsaka, J. Bass, K. M. Ramsey, 2007, Annual review of nutrition.

Altered sleep regulation in leptin-deficient mice.

F. Turek, J. Bass, C. Dugovic, 2006, American journal of physiology. Regulatory, integrative and comparative physiology.

Pulsed glucocorticoids enhance dystrophic muscle performance through epigenetic-metabolic reprogramming.

Saptarsi M. Haldar, G. Barish, J. Bass, 2019, JCI insight.

A sense of time: how molecular clocks organize metabolism

A. Kohsaka, J. Bass, Joseph Bass, 2007, Trends in Endocrinology & Metabolism.

Understanding Circadian Mechanisms of Sudden Cardiac Death: A Report From the National Heart, Lung, and Blood Institute Workshop, Part 2: Population and Clinical Considerations

F. Scheer, J. Nerbonne, C. Garnett, 2021, Circulation. Arrhythmia and electrophysiology.

Circadian NAD(P)(H) cycles in cell metabolism.

J. Bass, K. M. Ramsey, D. Levine, 2021, Seminars in cell & developmental biology.

Neurogenetic basis for circadian regulation of metabolism by the hypothalamus

J. Bass, J. Cedernaes, Nathan J Waldeck, 2019, Genes & development.

Phosphatase of Regenerating Liver-1 Selectively Times Circadian Behavior in Darkness via Function in PDF Neurons and Dephosphorylation of TIMELESS

R. Allada, M. Rosbash, D. Lee, 2020, Current Biology.

Requirement for NF-κB in maintenance of molecular and behavioral circadian rhythms in mice

G. Barish, D. Guttridge, J. Bass, 2018, Genes & development.

Roadmap on biology in time varying environments

Michael J Rust, Jared E. Toettcher, Kevin B. Wood, 2021, Physical biology.

Circadian Clock Interactio n with HIF 1 a Mediates Oxygenic Metabolism and Anaerobic Glycolysis in Skeletal Muscle Graphical

J. Bass, Yumiko Kobayashi, K. M. Ramsey, 2016 .

Downregulation of the Apelinergic Axis Accelerates Aging, whereas Its Systemic Restoration Improves the Mammalian Healthspan.

A. Ghosh, M. Eren, D. Vaughan, 2017, Cell reports.

Metabolic Syndrome Altered sleep regulation in leptin-deficient mice

F. Turek, J. Bass, C. Dugovic, 2005 .

Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice

J. Takahashi, T. Wiltshire, J. Hogenesch, 2013, eLife.

Generation of N-Ethyl-N-nitrosourea (ENU) Diabetes Models in Mice Demonstrates Genotype-specific Action of Glucokinase Activators*

J. Takahashi, M. Vitaterna, A. Kohsaka, 2011, The Journal of Biological Chemistry.

Forever (FGF) 21

J. Bass, 2013, Nature Medicine.

Circadian rhythms: Redox redux

J. Takahashi, J. Bass, 2011, Nature.

Circadian disruption in the pathogenesis of metabolic syndrome.

J. Bass, E. Maury, H. Hong, 2014, Diabetes & metabolism.

Understanding Circadian Mechanisms of Sudden Cardiac Death: A Report From the National Heart, Lung, and Blood Institute Workshop, Part 1: Basic and Translational Aspects

F. Scheer, J. Nerbonne, C. Garnett, 2021, Circulation. Arrhythmia and electrophysiology.

Circadian time signatures of fitness and disease

M. Lazar, J. Bass, 2016, Science.

Impact of Sleep and Circadian Disruption on Energy Balance and Diabetes: A Summary of Workshop Discussions.

F. Scheer, A. Pack, S. Panda, 2015, Sleep.

Physiology: On time metabolism

J. Bass, 2011, Nature.

Sleepless in America: a pathway to obesity and the metabolic syndrome?

F. Turek, J. Bass, 2005, Archives of internal medicine.

Circadian Transcription from Beta Cell Function to Diabetes Pathophysiology

J. Bass, K. M. Ramsey, B. Marcheva, 2016, Journal of biological rhythms.

Fusion of Insulin Receptor Ectodomains to Immunoglobulin Constant Domains Reproduces High-affinity Insulin Binding in Vitro*

D. Steiner, J. Bass, M. Pashmforoush, 1996, The Journal of Biological Chemistry.

Decoding obesity in the brainstem

J. Bass, J. Cedernaes, 2016, eLife.

The molecular clock as a metabolic rheostat

J. Bass, K. M. Ramsey, M. Perelis, 2015, Diabetes, obesity & metabolism.

Clock genes and metabolic disease.

J. Bass, K. M. Ramsey, B. Marcheva, 2009, Journal of applied physiology.

Animal Models for Disorders of Chronobiology

J. Bass, K. M. Ramsey, 2011 .

Congenital Insulin Resistance Associated with a Conformational Alteration in a Conserved β-Sheet in the Insulin Receptor L1 Domain*

D. Steiner, F. Grigorescu, G. Bell, 1999, The Journal of Biological Chemistry.

A divergent INS protein in Caenorhabditis elegans structurally resembles human insulin and activates the human insulin receptor.

M. Weiss, J. Bass, J. Wilken, 2003, Genes & development.

Impact of circadian time of dosing on cardiomyocyte-autonomous effects of glucocorticoids

J. Molkentin, J. Bass, Manoj Panta, 2021, bioRxiv.

The Role of Clock Genes in Cardiometabolic Disease Clock genes and metabolic disease

J. Bass, K. M. Ramsey, B. Marcheva, 2009 .

Lean gene and the clock machine

J. Bass, K. M. Ramsey, 2007, Proceedings of the National Academy of Sciences.

When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging.

Dudley Lamming, S. Panda, J. Bass, 2023, Cell metabolism.

Sleep-wake regulation is altered in leptin-resistant (db/db) genetically obese and diabetic mice.

F. Turek, J. Bass, D. Williams, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

METABOLIC HEALTH Pancreatic b cell enhancers regulate rhythmic transcription of genes controlling insulin secretion

Alan L. Hutchison, G. Barish, A. Dinner, 2015 .

Circadian mechanisms in adipose tissue bioenergetics and plasticity

J. Bass, Chelsea Hepler, 2023, Genes & development.