M. Gumbleton

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Combined expression of caveolin-1 and an activated AKT/mTOR pathway predicts reduced disease-free survival in clinically confined renal cell carcinoma

B. Jasani, L. Campbell, K. Edwards, 2008, British Journal of Cancer.

Nuclear localisation and pDNA condensation in non‐viral gene delivery

J. Birchall, M. Gumbleton, E. Collins, 2007, The journal of gene medicine.

Examination of the biophysical interaction between plasmid DNA and the polycations, polylysine and polyornithine, as a basis for their differential gene transfection in-vitro.

J. Hadgraft, J. Birchall, M. Gumbleton, 2000, International journal of pharmaceutics.

Physical stability and in-vitro gene expression efficiency of nebulised lipid-peptide-DNA complexes.

J. Birchall, M. Gumbleton, I. Kellaway, 2000, International journal of pharmaceutics.

Endocytic Uptake, Transport and Macromolecular Interactions of Anionic PAMAM Dendrimers within Lung Tissue

M. Gumbleton, P. Griffiths, C. Morris, 2017, Pharmaceutical Research.

Caveolae and the caveolins in human disease.

L. Campbell, M. Gumbleton, K. Ritchie, 2001, Advanced drug delivery reviews.

Caveolin-1 expression and caveolae biogenesis during cell transdifferentiation in lung alveolar epithelial primary cultures.

L. Campbell, M. Gumbleton, A. Hollins, 1999, Biochemical and biophysical research communications.

Endocytosis at the blood–brain barrier: From basic understanding to drug delivery strategies

M. Gumbleton, Mathew W. Smith, 2006, Journal of drug targeting.

Comparison of vasodilatory responses to nitroglycerin and its dinitrate metabolites in human veins

W. Haefeli, L. Benet, T. Blaschke, 1992, Clinical pharmacology and therapeutics.

Destabilization of α-Helical Structure in Solution Improves Bactericidal Activity of Antimicrobial Peptides: Opposite Effects on Bacterial and Viral Targets

K. Beck, M. Gumbleton, C. Morris, 2016, Antimicrobial Agents and Chemotherapy.

DeliveryBiocompatibility following Airway Antimicrobial Activity while Improving Lung Model Membrane Interactions, and Conformation, Maintains the Active Peptide Pegylation of Antimicrobial Peptides

K. Beck, M. Gumbleton, C. Morris, 2014 .

Pegylation of Antimicrobial Peptides Maintains the Active Peptide Conformation, Model Membrane Interactions, and Antimicrobial Activity while Improving Lung Tissue Biocompatibility following Airway Delivery

K. Beck, M. Gumbleton, C. Morris, 2012, Antimicrobial Agents and Chemotherapy.

Targeted Drug Delivery Through the Respiratory System: Molecular Control on Lung Absorption and Disposition

M. Gumbleton, M. Sakagami, 2011 .

Understanding endocytic pathways and intracellular trafficking: a prerequisite for effective design of advanced drug delivery systems.

Mark Gumbleton, Ruth Duncan, M. Gumbleton, 2003, Advanced drug delivery reviews.

Modulation of the fate of zein nanoparticles by their coating with a Gantrez® AN-thiamine polymer conjugate

M. Gumbleton, J. Irache, M. Abdulkarim, 2019, International journal of pharmaceutics: X.

Mannosylated Nanoparticles for Oral Immunotherapy in a Murine Model of Peanut Allergy.

M. Gumbleton, J. Irache, C. Gamazo, 2019, Journal of pharmaceutical sciences.

Mucus permeating thiolated self-emulsifying drug delivery systems.

M. Gumbleton, A. Bernkop‐Schnürch, A. Partenhauser, 2016, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Evaluation of the immortalised mouse brain capillary endothelial cell line, b.End3, as an in vitro blood–brain barrier model for drug uptake and transport studies

L. Campbell, M. Gumbleton, Y. Omidi, 2003, Brain Research.

Zwitterionic self-assembled nanoparticles as carriers for Plasmodium targeting in malaria oral treatment.

M. Gumbleton, S. Borrós, M. Abdulkarim, 2021, Journal of controlled release : official journal of the Controlled Release Society.

Kinetics of nicotine and its metabolites in animals

M. Gumbleton, J. Gabrielsson, 1993 .

PGSE-NMR and SANS studies of the interaction of model polymer therapeutics with mucin.

S. King, M. Gumbleton, P. Griffiths, 2010, Biomacromolecules.

Drug Metabolism and Laboratory Anesthetic Protocols in the Rat: Examination of Antipyrine Pharmacokinetics

L. Benet, M. Gumbleton, 1991, Pharmaceutical Research.

Caveolin-1 in renal cell carcinoma promotes tumour cell invasion, and in co-operation with pERK predicts metastases in patients with clinically confined disease

L. Campbell, M. Gumbleton, Mathew W. Smith, 2013, Journal of Translational Medicine.

Cell selective glucocorticoid induction of caveolin-1 and caveolae in differentiating pulmonary alveolar epithelial cell cultures.

L. Campbell, M. Gumbleton, J. Barar, 2007, Biochemical and biophysical research communications.

Spatial expression and functionality of drug transporters in the intact lung: objectives for further research.

M. Gumbleton, C. Morris, Mathew W. Smith, 2011, Advanced drug delivery reviews.

Aerosols for Macromolecule Delivery Design Challenges and Solutions

M. Gumbleton, G. Taylor, 2004 .

Caveolae as potential macromolecule trafficking compartments within alveolar epithelium.

M. Gumbleton, 2001, Advanced drug delivery reviews.

The possible relationship between hepatic drug metabolism and ketoconazole enhancement of cyclosporine nephrotoxicity.

M. Gumbleton, G. Hawksworth, P. Whiting, 1985, Transplantation.

Self-emulsifying drug delivery system: Mucus permeation and innovative quantification technologies.

M. Gumbleton, P. Sharma, M. Abdulkarim, 2019, Advanced drug delivery reviews.

Simultaneous pharmacodynamic modeling of the non-steady-state effects of three oral doses of 1,3-glyceryl dinitrate upon blood pressure in healthy volunteers

L. Benet, M. Gumbleton, 1993, Journal of Pharmacokinetics and Biopharmaceutics.

Pharmacological activity of the dinitrate metabolites of nitroglycerin following their oral administration to healthy volunteers.

L. Benet, M. Gumbleton, 1991, British journal of clinical pharmacology.

1,2-and 1,3-dinitrate metabolites of nitroglycerin : spectroscopic characterization and initial administration to man

L. Benet, J. Cashman, M. Gumbleton, 1991 .

Maximal extent of translocation of single-walled carbon nanotubes from lung airways of the rat.

B. Hoogendoorn, M. Gumbleton, C. Morris, 2013, Environmental toxicology and pharmacology.

Caveolin-1 overexpression predicts poor disease-free survival of patients with clinically confined renal cell carcinoma

L. Campbell, M. Gumbleton, D. Griffiths, 2003, British Journal of Cancer.

Gene expression in an intact ex-vivo skin tissue model following percutaneous delivery of cationic liposome-plasmid DNA complexes.

J. Hadgraft, J. Birchall, L. Campbell, 2000, International journal of pharmaceutics.

Humidified Warmed CO2 Treatment Therapy Strategies Can Save Lives With Mitigation and Suppression of SARS-CoV-2 Infection: An Evidence Review

M. Gumbleton, K. Harding, A. El-Betany, 2020, Frontiers in Medicine.

Nanoparticle diffusion within intestinal mucus: Three-dimensional response analysis dissecting the impact of particle surface charge, size and heterogeneity across polyelectrolyte, pegylated and viral particles.

M. Gumbleton, P. Griffiths, A. Bernkop‐Schnürch, 2015, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Targeting caveolae for vesicular drug transport.

L. Campbell, M. Gumbleton, Y. Omidi, 2003, Journal of controlled release : official journal of the Controlled Release Society.

Interpretation and Utilization of Effect and Concentration Data Collected in an in Vivo Pharmacokinetic and in Vitro Pharmacodynamic Study

L. Benet, M. Gumbleton, Suneel K. Gupta, 1993, Pharmaceutical Research.

Constitutive Expression of P-Glycoprotein in Normal Lung Alveolar Epithelium and Functionality in Primary Alveolar Epithelial Cultures

L. Campbell, M. Gumbleton, A. Hollins, 2003, Journal of Pharmacology and Experimental Therapeutics.

Oral Immunogenicity in Mice and Sows of Enterotoxigenic Escherichia Coli Outer-Membrane Vesicles Incorporated into Zein-Based Nanoparticles

M. Gumbleton, J. Irache, C. Gamazo, 2019, Vaccines.

Stereoselective and concentration-dependent polarised epithelial permeability of a series of phosphoramidate triester prodrugs of d4T: an in vitro study in Caco-2 and MDCK cell monolayers

M. Gumbleton, L. Kandalaft, D. Siccardi, 2003 .

The inhibition of phagocytosis of respirable microspheres by alveolar and peritoneal macrophages.

M. Gumbleton, I. Kellaway, P. Dickinson, 2002, International journal of pharmaceutics.

Dermatopathology Downregulation and altered spatial pattern of caveolin-1 in chronic plaque psoriasis

L. Campbell, M. Gumbleton, C. Griffiths, 2002 .

Downregulation and altered spatial pattern of caveolin‐1 in chronic plaque psoriasis

L. Campbell, M. Gumbleton, C. Griffiths, 2002, The British journal of dermatology.

P-glycoprotein (MDR1) functional activity in human alveolar epithelial cell monolayers

M. Gumbleton, C. Ehrhardt, C. Lehr, 2007, Cell and Tissue Research.

Caveolae: An Alternative Membrane Transport Compartment

L. Campbell, M. Gumbleton, A. Abulrob, 2000, Pharmaceutical Research.

Caveolin and its cellular and subcellular immunolocalisation in lung alveolar epithelium: implications for alveolar epithelial type I cell function

B. Jasani, L. Campbell, M. Gumbleton, 1999, Cell and Tissue Research.

RT‐PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell models

M. Gumbleton, C. Ehrhardt, Danielle Francombe, 2009 .

Primary porcine brain microvascular endothelial cells: Biochemical and functional characterisation as a model for drug transport and targeting

M. Gumbleton, Y. Omidi, Mathew W. Smith, 2007, Journal of drug targeting.

Basic aspects of cell growth and cell cycle in culture

L. Campbell, M. Gumbleton, 2002 .

Models of the alveolar epithelium

M. Gumbleton, C. Lehr, S. Fuchs, 2002 .

Enhanced pulmonary absorption of a macromolecule through coupling to a sequence-specific phage display-derived peptide.

M. Gumbleton, P. Griffiths, N. McKeown, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Differentiation of human alveolar epithelial cells in primary culture: morphological characterization and synthesis of caveolin-1 and surfactant protein-C

K. Roemer, M. Gumbleton, C. Lehr, 2002, Cell and Tissue Research.

Temporal dependence of ectopeptidase expression in alveolar epithelial cell culture: implications for study of peptide absorption.

M. Gumbleton, B. Forbes, C. Wilson, 1999, International journal of pharmaceutics.

Evaluation of nanoparticles as oral vehicles for immunotherapy against experimental peanut allergy.

M. Gumbleton, J. Irache, C. Gamazo, 2017, International journal of biological macromolecules.

Selectivity in the impact of P-glycoprotein upon pulmonary absorption of airway-dosed substrates: a study in ex vivo lung models using chemical inhibition and genetic knockout.

M. Gumbleton, C. Morris, G. Aljayyoussi, 2013, Journal of pharmaceutical sciences.

Caveolin expression during chondrogenesis in the avian limb

L. Campbell, M. Gumbleton, A. Hollins, 2002, Developmental dynamics : an official publication of the American Association of Anatomists.

In vivo evaluation of an oral self‐emulsifying drug delivery system (SEDDS) for exenatide

M. Gumbleton, A. Bernkop‐Schnürch, Flavia Laffleur, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Peptide sequences mediating tropism to intact blood–brain barrier: An in vivo biodistribution study using phage display

M. Gumbleton, Mathew W. Smith, Ghaith Al-Jayyoussi, 2012, Peptides.

Pharmaceutical nanoparticles and the mucin biopolymer barrier.

M. Gumbleton, P. Griffiths, G. Aljayyoussi, 2012, BioImpacts : BI.

Topical, immunomodulatory epoxy-tiglianes induce biofilm disruption and healing in acute and chronic skin wounds

P. Parsons, M. Gumbleton, Carly J. Pierce, 2022, Science Translational Medicine.

Polylysine and Polyornithine Gene Transfer Complexes: A Study of Complex Stability and Cellular Uptake as a Basis for their Differential in-vitro Transfection Efficiency

M. Gumbleton, E. Ramsay, 2002, Journal of drug targeting.

Phospho-4e-BP1 and eIF4E overexpression synergistically drives disease progression in clinically confined clear cell renal cell carcinoma.

B. Jasani, L. Campbell, M. Gumbleton, 2015, American journal of cancer research.

Impact of different hydrophobic ion pairs of octreotide on its oral bioavailability in pigs

M. Gumbleton, S. Bonengel, F. Prüfert, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Synthesis, Anti-Human Immunodeficiency Virus Activity and Esterase Lability of Some Novel Carboxylic Ester-Modified Phosphoramidate Derivatives of Stavudine (d4T)

E. De Clercq, M. Gumbleton, J. Balzarini, 1998, Antiviral chemistry & chemotherapy.

Inhaled extended-release microparticles of heparin elicit improved pulmonary pharmacodynamics against antigen-mediated airway hyper-reactivity and inflammation.

J. Birchall, M. Gumbleton, Y. Özsoy, 2012, Journal of controlled release : official journal of the Controlled Release Society.

A Systematic Review and Meta-Analysis Reveals Altered Drug Pharmacokinetics in Humans During Acute Exposure to Terrestrial High Altitude-Clinical Justification for Dose Adjustment?

M. Gumbleton, B. Stacey, D. Bailey, 2018, High altitude medicine & biology.

A simple zero length surface-modification approach for preparing novel bifunctional supports for co-immobilisation studies

M. Gumbleton, C. Allender, P. R. Davies, 2012 .

In-vivo effects of itraconazole on hepatic mixed-function oxidase.

M. Gumbleton, M. Shaw, P. Nicholls, 1988, The Journal of antimicrobial chemotherapy.

INTERACTION OF CYCLOSPORIN AND ITRACONAZOLE

M. Gumbleton, M. Shaw, P. Nicholls, 1987, The Lancet.

Stereoselective and Concentration-Dependent Polarized Epithelial Permeability of a Series of Phosphoramidate Triester Prodrugs of d4T: An in Vitro Study in Caco-2 and Madin-Darby Canine Kidney Cell Monolayers

M. Gumbleton, C. Mcguigan, L. Kandalaft, 2003, Journal of Pharmacology and Experimental Therapeutics.

Differential Effects of Anesthetic Regimens on Gentamicin Pharmacokinetics in the Rat: A Comparison with Chronically Catheterized Conscious Animals

M. Gumbleton, G. Taylor, P. Nicholls, 2004, Pharmaceutical Research.

Stereospecific chemical and enzymatic stability of phosphoramidate triester prodrugs of d4T in vitro.

M. Gumbleton, Y. Omidi, D. Siccardi, 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Challenges in inhaled product development and opportunities for open innovation.

Mark Gumbleton, Ben Forbes, Lea Ann Dailey, 2011, Advanced drug delivery reviews.

Immunolocalization of Caveolin-1 in Rat and Human Mesothelium

B. Jasani, L. Campbell, M. Gumbleton, 2004, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Dose-response and time-response biochemical and histological study of potassium dichromate-induced nephrotoxicity in the rat.

M. Gumbleton, P. Nicholls, 1988, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Satellitosis, a Crosstalk between Neurons, Vascular Structures and Neoplastic Cells in Brain Tumours; Early Manifestation of Invasive Behaviour

M. Gumbleton, G. Pilkington, A. Naccarato, 2020, Cancers.

INSIDIA: A FIJI Macro Delivering High‐Throughput and High‐Content Spheroid Invasion Analysis

Chiara Moriconi, Valentina Palmieri, Riccardo Di Santo, 2017, Biotechnology journal.

Methods to determine the interactions of micro- and nanoparticles with mucus.

Mark Gumbleton, Sejin Oh, Matthew Wilcox, 2015, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Activated extracellular signal‐regulated kinase is an independent prognostic factor in clinically confined renal cell carcinoma

L. Campbell, M. Gumbleton, D. Griffiths, 2009, Cancer.

Evidence of Nonuniformity in Urothelium Barrier Function between the Upper Urinary Tract and Bladder.

M. Gumbleton, C. Allender, T. Harrah, 2016, The Journal of urology.

Auto-fluorescent PAMAM-based dendritic molecules and their potential application in pharmaceutical sciences.

M. Gumbleton, P. Griffiths, N. McKeown, 2020, International journal of pharmaceutics.

Local delivery to malignant brain tumors: potential biomaterial-based therapeutic/adjuvant strategies.

B. Newland, M. Gumbleton, M. Alghamdi, 2021, Biomaterials science.

An ex vivo investigation into the transurothelial permeability and bladder wall distribution of the nonsteroidal anti-inflammatory ketorolac.

M. Gumbleton, C. Allender, T. Harrah, 2014, Molecular pharmaceutics.

Anaesthetic influences on brain haemodynamics in the rat and their significance to biochemical, neuropharmacological and drug disposition studies.

M. Gumbleton, R. Sewell, G. Taylor, 1989, Biochemical pharmacology.

The renin-angiotensin system and intraperitoneal toxicity: possible basis to urethane anaesthesia-induced reductions in renal clearance in the rat.

M. Gumbleton, P. Nicholls, G. Taylor, 1988, Archives internationales de pharmacodynamie et de therapie.

Urethane anaesthesia: altered pharmacokinetics of the renally eliminated organic anion p-aminohippuric acid

M. Gumbleton, G. Taylor, P. Nicholls, 1987 .

Heparin-based, injectable microcarriers for controlled delivery of interleukin-13 to the brain.

B. Newland, C. Werner, A. Rosser, 2020, Biomaterials science.

In vitro assessment of cephaloridine nephrotoxicity: comparison of renal cortical slice and renal tubule fragment techniques.

M. Gumbleton, P. Nicholls, R. Cruz, 1988, Journal of pharmacological methods.

RAT RENAL TUBULE FRAGMENTS: A SENSITIVE PREPARATION FOR THE STUDY OF DRUG INDUCED NEPHROTOXICITY

M. Gumbleton, P. Nicholls, R. Hernandez Cruz, 1985 .

Transport of phosphatidylcholine in MDR3-negative epithelial cell lines via drug-induced MDR1 P-glycoprotein.

M. Gumbleton, A. Abulrob, 1999, Biochemical and biophysical research communications.

Caveolin-1, a Key Mediator Across Multiple Pathways in Glioblastoma and an Independent Negative Biomarker of Patient Survival

M. Gumbleton, G. Pilkington, P. Civita, 2021, Frontiers in Oncology.

Growth of hormone-dependent MCF-7 breast cancer cells is promoted by constitutive caveolin-1 whose expression is lost in an EGF-R-mediated manner during development of tamoxifen resistance

R. Nicholson, J. Gee, K. Taylor, 2010, Breast Cancer Research and Treatment.

Caveolae-mediated membrane transport.

M. Gumbleton, 2001, Advanced drug delivery reviews.

Improved gas chromatographic assay for the simultaneous determination of nitroglycerin and its mono- and dinitrate metabolites.

L. Benet, M. Gumbleton, D. Lau, 1992, Journal of chromatography.

Phospho-4 eBP 1 and eIF 4 E overexpression synergistically drives disease progression in clinically confined clear cell renal cell carcinoma

B. Jasani, L. Campbell, M. Gumbleton, 2015 .

Expression and Transport Functionality of FcRn within Rat Alveolar Epithelium: A Study in Primary Cell Culture and in the Isolated Perfused Lung

Lee Campbell, Mark Gumbleton, Lana E. Kandalaft, 2005, Pharmaceutical Research.

Pharmacokinetic studies of the nitroglycerin metabolites, 1,2‐ and 1,3‐ glyceryl dinitrates, in the rat

L. Benet, M. Gumbleton, D. Lau, 1991, Biopharmaceutics & drug disposition.

Percutaneous Penetration Kinetics of Nitroglycerin and Its Dinitrate Metabolites Across Hairless Mouse Skin in Vitro

R. Guy, L. Benet, M. Gumbleton, 1991, Pharmaceutical Research.

Progress and limitations in the use of in vitro cell cultures to serve as a permeability screen for the blood-brain barrier.

M Gumbleton, K. Audus, M. Gumbleton, 2001, Journal of pharmaceutical sciences.

Processes of Drug Handling by the Body

M. Gumbleton, 2005 .

Investigating detrusor muscle concentrations of oxybutynin after intravesical delivery in an ex vivo porcine model.

M. Gumbleton, C. Allender, T. Harrah, 2015, Journal of pharmaceutical sciences.

Absorption of ipratropium and l-carnitine into the pulmonary circulation of the ex-vivo rat lung is driven by passive processes rather than active uptake by OCT/OCTN transporters.

M. Gumbleton, C. Morris, J. Keogh, 2015, International journal of pharmaceutics.

The particle has landed--characterizing the fate of inhaled pharmaceuticals.

M. Gumbleton, J. Patton, C. Ehrhardt, 2010, Journal of aerosol medicine and pulmonary drug delivery.

A human co‐culture cell model incorporating microglia supports glioblastoma growth and migration, and confers resistance to cytotoxics

M. Gumbleton, Diana M. Leite, G. Pilkington, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Quantifying the effects of antibiotic treatment on the extracellular polymer network of antimicrobial resistant and sensitive biofilms using multiple particle tracking

M. Gumbleton, M. Abdulkarim, T. Walsh, 2021, NPJ biofilms and microbiomes.

A89 Molecularlyimprintedpolymers:macro- moleculerecognition

M. Gumbleton, C. Allender, J. Bowen, 2010 .

Characterization and astrocytic modulation of system L transporters in brain microvasculature endothelial cells

M. Gumbleton, Y. Omidi, J. Barar, 2008, Cell biochemistry and function.

Current Progress Toward a Better Understanding of Drug Disposition Within the Lungs: Summary Proceedings of the First Workshop on Drug Transporters in the Lungs.

Mark Gumbleton, Tetsuya Terasaki, William Couet, 2017, Journal of pharmaceutical sciences.

The Differential Absorption of a Series of P-Glycoprotein Substrates in Isolated Perfused Lungs from Mdr1a/1b Genetic Knockout Mice can be Attributed to Distinct Physico-Chemical Properties: an Insight into Predicting Transporter-Mediated, Pulmonary Specific Disposition

M. Gumbleton, C. Luscombe, Chris D. Edwards, 2017, Pharmaceutical Research.

The Effect of Fatty Acids and Analogues upon Intracellular Levels of Doxorubicin in Cells Displaying P-Glycoprotein Mediated Multidrug Resistance

M. Mason, M. Gumbleton, R. Bryce, 2000, Journal of drug targeting.

Aerosols for macromolecule delivery

M. Gumbleton, G. Taylor, 2004 .

Statistical Modelling of the Formulation Variables in Non-Viral Gene Delivery Systems

J C Birchall, C A Waterworth, C Luscombe, 2001, Journal of drug targeting.

Identification and biological evaluation of grapefruit oil components as potential novel efflux pump modulators in methicillin-resistant Staphylococcus aureus bacterial strains.

M. Gumbleton, C. Simons, M. Suller, 2004, Phytochemistry.

Poly(ethylene glycol) based nanotubes for tuneable drug delivery to glioblastoma multiforme

B. Newland, Wenxin Wang, C. Werner, 2020, Nanoscale advances.

Quantifying the effects of antibiotic treatment on the extracellular polymer network of antimicrobial resistant and sensitive biofilms using multiple particle tracking

M. Gumbleton, M. Abdulkarim, T. Walsh, 2021, npj Biofilms and Microbiomes.

Endocytic Uptake, Transport and Macromolecular Interactions of Anionic PAMAM Dendrimers within Lung Tissue

M. Gumbleton, P. Griffiths, C. Morris, 2017, Pharmaceutical Research.

Lung surfactant phospholipids inhibit the uptake of respirable microspheres by the alveolar macrophage NR8383

M. Gumbleton, I. Kellaway, P. Dickinson, 2002, The Journal of pharmacy and pharmacology.

Differential Influence of Laboratory Anaesthetic Regimens upon Renal and Hepatosplanchnic Haemodynamics in the Rat

M. Gumbleton, G. Taylor, P. Nicholls, 1990, The Journal of pharmacy and pharmacology.

Phage display identification of functional binding peptides against 4-acetamidophenol (Paracetamol): an exemplified approach to target low molecular weight organic molecules.

A. Brancale, M. Gumbleton, C. Allender, 2007, Biochemical and biophysical research communications.

The particle has landed--characterizing the fate of inhaled pharmaceuticals.

M. Gumbleton, J. Patton, C. Ehrhardt, 2010, Journal of aerosol medicine and pulmonary drug delivery.

RT-PCR analysis of ABC, SLC and SLCO drug transporters in human lung epithelial cell models.

M. Gumbleton, C. Ehrhardt, Danielle Francombe, 2009, The Journal of pharmacy and pharmacology.

Methods to determine the interactions of micro- and nanoparticles with mucus.

M. Gumbleton, M. Wilcox, P. Griffiths, 2015, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Caveolin-1 in renal cell carcinoma promotes tumour cell invasion, and in co-operation with pERK predicts metastases in patients with clinically confined disease

L. Campbell, M. Gumbleton, Mathew W. Smith, 2013, Journal of Translational Medicine.

Pharmacokinetic Considerations in Rational Drug Design

W. Sneader, M. Gumbleton, 1994, Clinical pharmacokinetics.

Inhaled extended-release microparticles of heparin elicit improved pulmonary pharmacodynamics against antigen-mediated airway hyper-reactivity and inflammation.

J. Birchall, M. Gumbleton, Y. Özsoy, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Biological Membranes and Barriers

M. Gumbleton, Y. Omidi, 2015 .

Microcalorimetry does not predict the cellular phagocytosis of latex microspheres.

M. Gumbleton, I. Kellaway, P. Dickinson, 2000, International journal of pharmaceutics.

M. Gumbleton, C. Luscombe, Chris D. Edwards, 2017, Pharmaceutical Research.

M. Gumbleton, P. Griffiths, A. Bernkop‐Schnürch, 2015, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Coming out of the dark: the evolving role of fluorescence imaging in drug delivery research.

Mark Gumbleton, David J Stephens, M. Gumbleton, 2005, Advanced drug delivery reviews.