C. White

发表

Endothelial Akt activation by hyperoxia: role in cell survival.

Aftab Ahmad, Shama Ahmad, Ling-Yi L Chang, 2006, Free radical biology & medicine.

Cholesterol Interferes with the MTT Assay in Human Epithelial-Like (A549) and Endothelial (HLMVE and HCAE) Cells

Aftab Ahmad, Carl W. White, Aftab Ahmad, 2006, International journal of toxicology.

Limitations to oxygen diffusion and equilibration in in vitro cell exposure systems in hyperoxia and hypoxia.

C. White, B. K. Schneider, C. Allen, 2001, American journal of physiology. Lung cellular and molecular physiology.

Hypoxia increases production of interleukin-1 and tumor necrosis factor by human mononuclear cells.

P. Ghezzi, C. Dinarello, C. White, 1991, Cytokine.

Treatment with the catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of the sulfur mustard analog 2-chloroethyl ethyl sulfide.

R. Rancourt, C. White, B. Day, 2010, Free radical biology & medicine.

AEOL10150: A Novel Therapeutic For Rescue Treatment Following Toxic Gas Lung Injury

C. White, W. Powell, B. Day, 2010, ATS 2010.

Role of reactive oxygen and nitrogen species in olfactory epithelial injury by the sulfur mustard analogue 2-chloroethyl ethyl sulfide.

C. White, D. Orlicky, B. Day, 2011, American journal of respiratory cell and molecular biology.

AEOL10150: a novel therapeutic for rescue treatment after toxic gas lung injury.

C. White, W. Powell, B. Day, 2011, Free radical biology & medicine.

Catalytic antioxidant AEOL 10150 treatment ameliorates sulfur mustard analog 2-chloroethyl ethyl sulfide-associated cutaneous toxic effects.

R. Agarwal, C. White, N. Tewari-Singh, 2014, Free radical biology & medicine.

Recombinant tumor necrosis factor/cachectin and interleukin 1 pretreatment decreases lung oxidized glutathione accumulation, lung injury, and mortality in rats exposed to hyperoxia.

P. Ghezzi, C. Dinarello, C. White, 1987, The Journal of clinical investigation.

Analysis of TRPA1 antagonist, A-967079, in plasma using high-performance liquid chromatography tandem mass-spectrometry

C. White, N. Bortey-Sam, B. Logue, 2019, Journal of pharmaceutical analysis.

Commentary on "Hypoxia, hypoxic signaling, tissue damage, and detection of reactive oxygen species (ROS)".

C. White, 2006, Free radical biology & medicine.

Improved Lung Growth and Function through Hypoxia- Inducible Factor in Primate Chronic Lung Disease of Prematurity

J. Crapo, B. Yoder, Ling-Yi L Chang, 2022 .

Activation of hypoxia-inducible factors in hyperoxia through prolyl 4-hydroxylase blockade in cells and explants of primate lung.

C. White, B. K. Schneider, L. Flippin, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Antioxidant defenses in the preterm lung: role for hypoxia-inducible factors in BPD?

C. White, T. Asikainen, 2005, Toxicology and applied pharmacology.

Stimulation of HIF-1α, HIF-2α, and VEGF by prolyl 4-hydroxylase inhibition in human lung endothelial and epithelial cells

Aftab Ahmad, C. White, B. K. Schneider, 2005 .

Pulmonary antioxidant defenses in the preterm newborn with respiratory distress and bronchopulmonary dysplasia in evolution: implications for antioxidant therapy.

C. White, T. Asikainen, 2004, Antioxidants & redox signaling.

Perinatal Hypoxia-Inducible Factor Stabilization Preserves Lung Alveolar and Vascular Growth in Experimental BPD.

C. White, S. Kourembanas, S. Abman, 2020, American journal of respiratory and critical care medicine.

Hypoxia-Inducible Factors and Adenosine Signaling in Vascular Growth

Aftab Ahmad, Shama Ahmad, C. White, 2010 .

Optimised CRISPR-Cas9 mediated single molecule imaging for accurate quantification through endogenous expression

S. Hill, C. White, Jeremy A. Pike, 2018, bioRxiv.

Oxygen Administration Improves Survival but Worsens Cardiopulmonary Functions in Chlorine‐exposed Rats

C. White, L. Veress, Obiefuna C. Okponyia, 2018, American journal of respiratory cell and molecular biology.

Sarcoendoplasmic reticulum Ca(2+) ATPase. A critical target in chlorine inhalation-induced cardiotoxicity.

Aftab Ahmad, Shama Ahmad, C. White, 2015, American journal of respiratory cell and molecular biology.

Inflammatory biomarkers of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced skin injury in SKH-1 hairless mice.

R. Agarwal, C. White, N. Tewari-Singh, 2009, Toxicological sciences : an official journal of the Society of Toxicology.

CRISPR-Mediated Protein Tagging with Nanoluciferase to Investigate Native Chemokine Receptor Function and Conformational Changes

S. Hill, C. White, K. Pfleger, 2020, Cell chemical biology.

Aconitase is a sensitive and critical target of oxygen poisoning in cultured mammalian cells and in rat lungs.

P. R. Gardner, C. White, D. D. Nguyen, 1994, Proceedings of the National Academy of Sciences of the United States of America.

SERCA2 Regulates Non-CF and CF Airway Epithelial Cell Response to Ozone

M. Strand, S. Randell, R. Rancourt, 2011, PloS one.

Human Aldehyde Dehydrogenase 3A1 Inhibits Proliferation and Promotes Survival of Human Corneal Epithelial Cells*

Y. Koutalos, V. Vasiliou, J. DeGregori, 2005, Journal of Biological Chemistry.

Activation of NF-kappa B and elevation of MnSOD gene expression by thiol reducing agents in lung adenocarcinoma (A549) cells.

C. White, K. Das, Y. Lewis-Molock, 1995, The American journal of physiology.

Cutaneous Injury-Related Structural Changes and Their Progression following Topical Nitrogen Mustard Exposure in Hairless and Haired Mice

R. Agarwal, C. White, N. Tewari-Singh, 2014, PloS one.

Activation of a novel isoform of methionine adenosyl transferase 2A and increased S-adenosylmethionine turnover in lung epithelial cells exposed to hyperoxia.

V. Vasiliou, Aftab Ahmad, C. White, 2006, Free radical biology & medicine.

An Official American Thoracic Society Workshop Report: Chemical Inhalational Disasters. Biology of Lung Injury, Development of Novel Therapeutics, and Medical Preparedness.

S. Matalon, S. Jordt, E. Svendsen, 2017, Annals of the American Thoracic Society.

Acute cytotoxicity and increased vascular endothelial growth factor after in vitro nitrogen mustard vapor exposure

C. White, L. Veress, So-Young Kim, 2020, Annals of the New York Academy of Sciences.

Tissue plasminogen activator prevents mortality from sulfur mustard analog-induced airway obstruction.

C. White, J. Loader, L. Veress, 2013, American journal of respiratory cell and molecular biology.

Reduced thioredoxin increases proinflammatory cytokines and neutrophil influx in rat airways: modulation by airway mucus.

F. Accurso, R. Rancourt, C. White, 2007, Free radical biology & medicine.

Thioredoxin and dihydrolipoic acid inhibit elastase activity in cystic fibrosis sputum.

F. Accurso, R. Rancourt, C. White, 2005, American journal of physiology. Lung cellular and molecular physiology.

Neutrophils contribute to TNF induced myocardial tolerance to ischaemia.

A. Harken, C. White, A. Banerjee, 1992, Journal of molecular and cellular cardiology.

What makes the α1A‐adrenoceptor gene product assume an α1L‐adrenoceptor phenotype?

C. White, Linzi Lim, S. Ventura, 2019, British journal of pharmacology.

Tissue factor pathway inhibitor prevents airway obstruction, respiratory failure and death due to sulfur mustard analog inhalation.

R. Rancourt, Aftab Ahmad, C. White, 2013, Toxicology and applied pharmacology.

Enhancement of angiogenic effectors through hypoxia-inducible factor in preterm primate lung in vivo.

C. White, B. K. Schneider, T. Asikainen, 2006, American journal of physiology. Lung cellular and molecular physiology.

Absence of a p53 allele delays nitrogen mustard-induced early apoptosis and inflammation of murine skin.

R. Agarwal, C. White, N. Tewari-Singh, 2013, Toxicology.

Hypoxia-inducible factors HIF-1α and HIF-2α are decreased in an experimental model of severe respiratory distress syndrome in preterm lambs

C. White, S. Abman, J. Kinsella, 2007 .

Hypoxia induces hexokinase II gene expression in human lung cell line A549.

S. Deeb, Shama Ahmad, C. White, 2000, American journal of physiology. Lung cellular and molecular physiology.

Hypoxia protects human lung microvascular endothelial and epithelial-like cells against oxygen toxicity: role of phosphatidylinositol 3-kinase.

K. Stenmark, Aftab Ahmad, Shama Ahmad, 2003, American journal of respiratory cell and molecular biology.

Superoxide scavenging by Mn(II/III) tetrakis (1-methyl-4-pyridyl) porphyrin in mammalian cells.

P. R. Gardner, C. White, D. D. Nguyen, 1996, Archives of biochemistry and biophysics.

HIF stabilizing agents: shotgun or scalpel?

C. White, T. Asikainen, 2007, American journal of physiology. Lung cellular and molecular physiology.

Transplantation of Airway Epithelial Stem/Progenitor Cells: A Future for Cell‐Based Therapy

Shama Ahmad, C. White, S. Reynolds, 2017, American journal of respiratory cell and molecular biology.

Human tracheobronchial basal cells. Normal versus remodeling/repairing phenotypes in vivo and in vitro.

S. Groshong, Shama Ahmad, C. White, 2013, American journal of respiratory cell and molecular biology.

Determination of methyl isopropyl hydantoin from rat erythrocytes by gas-chromatography mass-spectrometry to determine methyl isocyanate dose following inhalation exposure.

C. White, L. Veress, C. Croutch, 2018, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Extracellular ATP Is an Autocrine/Paracrine Regulator of Hypoxia-induced Adventitial Fibroblast Growth

K. Stenmark, Shama Ahmad, C. White, 2002, The Journal of Biological Chemistry.

Lung manganese superoxide dismutase increases during cytokine-mediated protection against pulmonary oxygen toxicity in rats.

N. Taniguchi, C. White, K. Suzuki, 1994, American journal of respiratory cell and molecular biology.

Protein Kinase Cδ-dependent Induction of Manganese Superoxide Dismutase Gene Expression by Microtubule-active Anticancer Drugs*

Xiao-ling Guo, C. White, K. Das, 1998, The Journal of Biological Chemistry.

Lipoic acid suppression of neutrophil respiratory burst: effect of NADPH.

R. Rancourt, C. White, H. O'Neill, 2008, Antioxidants & redox signaling.

A Role for Mitochondrial Oxidative Stress in Sulfur Mustard Analog 2-Chloroethyl Ethyl Sulfide-Induced Lung Cell Injury and Antioxidant Protection

C. White, B. Day, Neal S. Gould, 2009, Journal of Pharmacology and Experimental Therapeutics.

Efficacy of Glutathione in Ameliorating Sulfur Mustard Analog-Induced Toxicity in Cultured Skin Epidermal Cells and in SKH-1 Mouse Skin In Vivo

R. Agarwal, C. White, N. Tewari-Singh, 2011, Journal of Pharmacology and Experimental Therapeutics.

Sulfur mustard analog induces oxidative stress and activates signaling cascades in the skin of SKH-1 hairless mice.

R. Agarwal, C. White, N. Tewari-Singh, 2009, Free radical biology & medicine.

Mechanisms of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced DNA damage in skin epidermal cells and fibroblasts.

R. Agarwal, C. White, N. Tewari-Singh, 2011, Free radical biology & medicine.

Nitrogen mustard exposure of murine skin induces DNA damage, oxidative stress and activation of MAPK/Akt-AP1 pathway leading to induction of inflammatory and proteolytic mediators.

R. Agarwal, C. White, N. Tewari-Singh, 2015, Toxicology letters.

Bronchiolitis Obliterans and Pulmonary Fibrosis after Sulfur Mustard Inhalation in Rats

C. White, J. Loader, L. Veress, 2018, American journal of respiratory cell and molecular biology.

2-Chloroethyl ethyl sulfide causes microvesication and inflammation-related histopathological changes in male hairless mouse skin.

R. Agarwal, C. White, N. Tewari-Singh, 2011, Toxicology.

Silibinin Attenuates Sulfur Mustard Analog-Induced Skin Injury by Targeting Multiple Pathways Connecting Oxidative Stress and Inflammation

R. Agarwal, C. White, N. Tewari-Singh, 2012, PloS one.

Biological and molecular mechanisms of sulfur mustard analogue-induced toxicity in JB6 and HaCaT cells: possible role of ataxia telangiectasia-mutated/ataxia telangiectasia-Rad3-related cell cycle checkpoint pathway.

R. Agarwal, C. White, N. Tewari-Singh, 2010, Chemical research in toxicology.

Transgenic mice with expression of elevated levels of copper-zinc superoxide dismutase in the lungs are resistant to pulmonary oxygen toxicity.

K. Avraham, C. White, Y. Groner, 1991, The Journal of clinical investigation.

Effect of oxygen on lung superoxide dismutase activities in premature baboons with bronchopulmonary dysplasia.

Xiao-ling Guo, C. White, D. Ikle, 1999, American journal of physiology. Lung cellular and molecular physiology.

Changes in pulmonary expression of hexokinase and glucose transporter mRNAs in rats adapted to hyperoxia.

Xiao-ling Guo, C. White, C. Allen, 1998, American journal of physiology. Lung cellular and molecular physiology.

Changes in pulmonary expression of hexokinase and glucose transporter mRNAs in rats adapted to hyperoxia

C. White, C. Allen, X. Guo, 1998 .

Interleukin 1 pretreatment decreases ischemia/reperfusion injury.

A. Harken, C. White, A. Banerjee, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Endotoxin pretreatment increases endogenous myocardial catalase activity and decreases ischemia-reperfusion injury of isolated rat hearts.

A. Harken, C. White, A. Banerjee, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Lung epithelial cells release ATP during ozone exposure: signaling for cell survival.

Aftab Ahmad, Shama Ahmad, C. White, 2005, Free radical biology & medicine.

Extracellular ATP-mediated Signaling for Survival in Hyperoxia-induced Oxidative Stress*

C. Leslie, Aftab Ahmad, Shama Ahmad, 2004, Journal of Biological Chemistry.

Plasma cysteine concentrations in infants with respiratory distress.

C. White, A. Rosenberg, R. Allen, 1994, The Journal of pediatrics.

Mutations of Vasopressin Receptor 2 Including Novel L312S Have Differential Effects on Trafficking

N. Pavlos, C. White, K. Pfleger, 2016, Molecular endocrinology.

Loss of lung mitochondrial aconitase activity due to hyperoxia in bronchopulmonary dysplasia in primates.

C. White, D. Ikle, R. L. Morton, 1998, American journal of physiology. Lung cellular and molecular physiology.

Elevation of Manganese Superoxide Dismutase Gene Expression by Thioredoxin

C. White, K. Das, Y. Lewis-Molock, 1995 .

Induction of thioredoxin and thioredoxin reductase gene expression in lungs of newborn primates by oxygen.

Xiao-ling Guo, C. White, K. Das, 1999, American journal of physiology. Lung cellular and molecular physiology.

Pulmonary antioxidant defense mechanisms.

C. White, J. Repine, 1985, Experimental lung research.

Minireview Pulmonary Antioxidant Defense Mechanisms

C. White, J. Repine, 1985 .

Hypoxia increases glutathione redox cycle and protects rat lungs against oxidants.

J. Jackson, C. White, J. Repine, 1988, Journal of applied physiology.

Thiol modulation of TNFα and IL-1 induced MnSOD gene expression and activation of NF-κB

C. White, K. Das, Y. Lewis-Molock, 1995, Molecular and Cellular Biochemistry.

Redox Paradox: Effect of N-acetylcysteine and Serum on Oxidation Reduction–sensitive Mitogen-activated Protein Kinase Signaling Pathways Materials and Methods

E. Chan, D. Riches, C. White, 2022 .

Intratracheal heparin improves plastic bronchitis due to sulfur mustard analog

R. Rancourt, C. White, J. Loader, 2015, Pediatric pulmonology.

Comparison of exhaled nitric oxide, serum eosinophilic cationic protein, and soluble interleukin‐2 receptor in exacerbations of pediatric asthma

C. White, S. Szefler, D. Leung, 1997, Pediatric pulmonology.

Thioredoxin liquefies and decreases the viscoelasticity of cystic fibrosis sputum.

M. King, F. Accurso, R. Rancourt, 2004, American journal of physiology. Lung cellular and molecular physiology.

Bcl-2 suppresses sarcoplasmic/endoplasmic reticulum Ca2+-ATPase expression in cystic fibrosis airways: role in oxidant-mediated cell death.

A. Perraud, S. Randell, Aftab Ahmad, 2009, American journal of respiratory and critical care medicine.

Intact human erythrocytes prevent hydrogen peroxide-mediated damage to isolated perfused rat lungs and cultured bovine pulmonary artery endothelial cells.

C. White, J. Repine, E. Berger, 1984, The Journal of clinical investigation.

Hyperoxia-induced DNA damage causes decreased DNA methylation in human lung epithelial-like A549 cells.

R. Rancourt, Shama Ahmad, C. White, 2004, Antioxidants & redox signaling.

Superoxide Radical and Iron Modulate Aconitase Activity in Mammalian Cells (*)

P. R. Gardner, C. White, L. Epstein, 1995, The Journal of Biological Chemistry.

Topical nitrogen mustard exposure causes systemic toxic effects in mice.

R. Agarwal, R. Rancourt, C. White, 2015, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Alleviation of methyl isocyanate−induced airway obstruction and mortality by tissue plasminogen activator

C. White, P. Bratcher, L. Veress, 2020, Annals of the New York Academy of Sciences.

Methyl isocyanate inhalation induces tissue factor-dependent activation of coagulation in rats

R. Rancourt, C. White, L. Veress, 2018, Drug and chemical toxicology.

Expression of manganese superoxide dismutase is not altered in transgenic mice with elevated level of copper-zinc superoxide dismutase.

K. Avraham, N. Taniguchi, C. White, 1993, Free radical biology & medicine.

The Role of Oxygen Free Radicals in Postasphyxia Cerebral Hypoperfusion in Newborn Lambs

C. White, A. Rosenberg, E. Murdaugh, 1989, Pediatric Research.

Use of transgenic animals to study disease models: hyperoxic lung injury and ischemic acute renal failure in "high SOD" mice.

K. Avraham, C. White, Y. Groner, 1992, Renal failure.

Accumulation of lung tissue oxidized glutathione (GSSG) as a marker of oxidant induced lung injury.

C. White, J. Repine, R. Mimmack, 1986, Chest.

Superoxide dismutase and catalase conjugated to polyethylene glycol increases endothelial enzyme activity and oxidant resistance.

C. White, B. Freeman, J. Repine, 1988, The Journal of biological chemistry.

Induction of peroxiredoxin gene expression by oxygen in lungs of newborn primates.

P. Pahl, C. White, X. Guo, 2001, American journal of respiratory cell and molecular biology.

Exhaled nitric oxide before and after montelukast sodium therapy in school‐age children with chronic asthma: A preliminary study

C. White, D. Bratton, P. Silkoff, 1999, Pediatric pulmonology.

Dimethylthiourea consumption reflects H2O2 concentrations and severity of acute lung injury.

J. Jackson, C. White, J. Repine, 1985, Journal of applied physiology.

Subtype selective fluorescent ligands based on ICI 118,551 to study the human β2‐adrenoceptor in CRISPR/Cas9 genome‐edited HEK293T cells at low expression levels

S. Hill, C. White, S. Briddon, 2021, Pharmacology research & perspectives.

Stimulation of HIF-1alpha, HIF-2alpha, and VEGF by prolyl 4-hydroxylase inhibition in human lung endothelial and epithelial cells.

Aftab Ahmad, C. White, B. K. Schneider, 2005, Free radical biology & medicine.

Alpha-lipoic acid induces elevated S-adenosylhomocysteine and depletes S-adenosylmethionine.

C. White, H. O'Neill, R. Allen, 2009, Free radical biology & medicine.

A Potential Regulator of Vasa Vasorum Neovascularization in Hypoxia-Induced Pulmonary Vascular Remodeling*

K. Stenmark, Shama Ahmad, C. White, 2015 .

Redox systems of the cell: Possible links and implications

C. White, K. Das, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Extracellular adenosine triphosphate: a potential regulator of vasa vasorum neovascularization in hypoxia-induced pulmonary vascular remodeling.

K. Stenmark, Shama Ahmad, C. White, 2005, Chest.

Comparison of exhaled nitric oxide to spirometry during emergency treatment of asthma exacerbations with glucocorticoids in children.

C. White, D. Leung, M. Lanz, 1999, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Transcriptome profiling of the newborn mouse lung response to acute ozone exposure.

C. White, A. Dakhama, S. Leach, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

Hypoxia-inducible factors HIF-1alpha and HIF-2alpha are decreased in an experimental model of severe respiratory distress syndrome in preterm lambs.

C. White, S. Abman, J. Kinsella, 2007, American journal of physiology. Lung cellular and molecular physiology.

Identification and Analysis of Phenyl Methyl Carbamate Released from Adducted Hemoglobin for Methyl Isocyanate Exposure Verification

C. White, L. Veress, B. Logue, 2022, SSRN Electronic Journal.

Cytokines increase rat lung antioxidant enzymes during exposure to hyperoxia.

P. Ghezzi, C. Dinarello, C. White, 1989, Journal of applied physiology.

Myeloperoxidase deficiency attenuates nitrogen mustard-induced skin injuries.

R. Agarwal, C. White, N. Tewari-Singh, 2014, Toxicology.

Mechanisms of cell injury and death in hyperoxia: role of cytokines and Bcl-2 family proteins.

C. White, C. Barazzone, Constance Barazzone, 2000, American journal of respiratory cell and molecular biology.

Antifibrinolytic mechanisms in acute airway injury after sulfur mustard analog inhalation.

R. Rancourt, Aftab Ahmad, C. White, 2014, American journal of respiratory cell and molecular biology.

Potential role for antiangiogenic proteins in the evolution of bronchopulmonary dysplasia.

C. White, M. Schwarz, M. L. Quintos-Alagheband, 2004, Antioxidants & redox signaling.

Rho kinase activation mediates adrenergic and cholinergic smooth muscle contractile responses in the mouse prostate gland.

C. White, J. Short, S. Ventura, 2013, European journal of pharmacology.

Acute Vaping of a golden Syrian Hamster is Feasible and Leads to Nicotine-Dependent Respiratory Tract Inflammation

C. White, P. Bratcher, J. Brinton, 2022, bioRxiv.

Expression of Transcription Factor GATA-6 in Alveolar Epithelial Cells Is Linked to Neonatal Lung Disease

C. White, V. Kinnula, M. Myllärniemi, 2010, Neonatology.

Effects of cytokines and endotoxin on lung manganese superoxide dismutase expression and immunohistochemical distribution.

N. Taniguchi, C. White, K. Suzuki, 1994, Chest.

Chlorine Gas Inhalation

C. White, James G. Martin, 2012 .

Effect of superoxide dismutase encapsulated in liposomes or conjugated with polyethylene glycol on neutrophil bactericidal activity in vitro and bacterial clearance in vivo.

J. White, C. White, B. Freeman, 1985, The American review of respiratory disease.

Oxidized phospholipids derived from ozone-treated lung surfactant extract reduce macrophage and epithelial cell viability.

R. Murphy, Shama Ahmad, C. White, 2002, Chemical research in toxicology.

Characterisation of the prostanoid receptor mediating inhibition of smooth muscle contractility in the rat prostate gland

C. White, D. Malone, B. Exintaris, 2010, Naunyn-Schmiedeberg's Archives of Pharmacology.

Glucose modulates cell death due to normobaric hyperoxia by maintaining cellular ATP.

C. White, C. Allen, 1998, The American journal of physiology.

Protection against pulmonary oxygen toxicity by interleukin-1 and tumor necrosis factor: Role of antioxidant enzymes and effect of cyclooxygenase inhibitors

P. Ghezzi, C. White, 1989, Biotherapy.

Fluorescence‐ and bioluminescence‐based approaches to study GPCR ligand binding

Leigh A. Stoddart, S. Hill, C. White, 2015, British journal of pharmacology.

Tissue factor signals airway epithelial basal cell survival via coagulation and protease-activated receptor isoforms 1 and 2.

R. Rancourt, Aftab Ahmad, Shama Ahmad, 2013, American journal of respiratory cell and molecular biology.

Glutamine protects mitochondrial structure and function in oxygen toxicity.

C. White, B. K. Schneider, L. Chang, 2001, American journal of physiology. Lung cellular and molecular physiology.

Loss of lung mitochondrial aconitase activity due to hyperoxia in bronchopulmonary dysplasia in primates.

C. White, D. Ikle, R. L. Morton, 1998, The American journal of physiology.

Adenosine A2A receptor-dependent proliferation of pulmonary endothelial cells is mediated through calcium mobilization, PI3-kinase and ERK1/2 pathways.

Aftab Ahmad, Shama Ahmad, J. Schaack, 2013, Biochemical and biophysical research communications.

Induction of thioredoxin and thioredoxin reductase gene expression in lungs of newborn primates by oxygen.

C. White, X. Guo, K. Das, 1999, The American journal of physiology.

Histopathological and immunohistochemical evaluation of nitrogen mustard-induced cutaneous effects in SKH-1 hairless and C57BL/6 mice.

R. Agarwal, C. White, N. Tewari-Singh, 2014, Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.

Elevated expression of surfactant proteins in newborn rats during adaptation to hyperoxia.

C. White, J. Shannon, C. Allen, 2001, American journal of respiratory cell and molecular biology.

Flavanone silibinin treatment attenuates nitrogen mustard-induced toxic effects in mouse skin.

R. Agarwal, C. White, N. Tewari-Singh, 2015, Toxicology and applied pharmacology.

Analysis of sodium 2-mercaptoethane sulfonate in rat plasma using high performance liquid chromatography tandem-mass spectrometry.

C. White, B. Logue, Heidi J. Nick, 2021, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

From the Cover: ImpairedProliferation and Differentiation of the Conducting Airway Epithelium Associated With Bronchiolitis Obliterans After Sulfur Mustard Inhalation Injury in Rats

R. Rancourt, C. White, L. Veress, 2017, Toxicological sciences : an official journal of the Society of Toxicology.

Thiol modulation of TNF alpha and IL-1 induced MnSOD gene expression and activation of NF-kappa B.

C. White, K. Das, Y. Lewis-Molock, 1995, Molecular and cellular biochemistry.

Sulfonylureas inhibit metabolic flux through rat liver pyruvate carboxylase reaction.

T. Patel, C. White, H. Rashed, 1988, The Journal of pharmacology and experimental therapeutics.

From the Cover: Catalytic Antioxidant Rescue of Inhaled Sulfur Mustard Toxicity.

C. White, B. Day, J. Loader, 2016, Toxicological sciences : an official journal of the Society of Toxicology.

Methyl mercaptan gas: mechanisms of toxicity and demonstration of the effectiveness of cobinamide as an antidote in mice and rabbits

C. White, G. Boss, H. Patel, 2022, Clinical toxicology.

Intramuscular cobinamide as an antidote to methyl mercaptan poisoning

C. White, G. Boss, D. Mukai, 2020, Inhalation toxicology.

Activation of NF-kappaB by antineoplastic agents. Role of protein kinase C.

C. White, K. Das, 1997, The Journal of biological chemistry.

Activation of NF-κB by Antineoplastic Agents

C. White, K. Das, 1997, The Journal of Biological Chemistry.

Detection of thioredoxin in human serum and biological samples using a sensitive sandwich ELISA with digoxigenin-labeled antibody.

C. White, K. Das, 1998, Journal of immunological methods.

Cytokine-induced nitric oxide formation in normal but not in neoplastic murine lung epithelial cell lines.

L. Dwyer-Nield, A. Malkinson, C. White, 1998, The American journal of physiology.

Stem and Progenitor Cells of the Airway Epithelium

Shama Ahmad, C. White, S. Reynolds, 2010 .

Activation of DNA damage repair pathways in response to nitrogen mustard-induced DNA damage and toxicity in skin keratinocytes.

Rajesh Agarwal, R. Agarwal, C. White, 2014, Mutation research.

Complex Formation between VEGFR2 and the β2-Adrenoceptor

K. Wood, S. Hill, C. White, 2019, Cell chemical biology.

Complex Formation between VEGFR 2 and the b-2 Adrenoceptor Graphical Abstract Highlights

K. Wood, S. Hill, C. White, 2019 .

C. White, J. Xie, S. Ventura, 2013, Organogenesis.

Detection of genome‐edited and endogenously expressed G protein‐coupled receptors

Leigh A. Stoddart, S. Hill, C. White, 2021, The FEBS journal.

O2 metabolites and neutrophil elastase synergistically cause edematous injury in isolated rat lungs.

C. White, J. Repine, R. Sandhaus, 1986, Journal of applied physiology.

Sulfur mustard inhalation: mechanisms of injury, alteration of coagulation, and fibrinolytic therapy

R. Rancourt, C. White, L. Veress, 2016, Annals of the New York Academy of Sciences.

Airway tissue factor-dependent coagulation activity in response to sulfur mustard analog 2-chloroethyl ethyl sulfide.

R. Rancourt, C. White, L. Veress, 2012, American journal of physiology. Lung cellular and molecular physiology.

Dimethylthiourea protects against chlorine induced changes in airway function in a murine model of irritant induced asthma

C. White, W. Powell, B. Day, 2010, Respiratory research.

Airway tissue plasminogen activator prevents acute mortality due to lethal sulfur mustard inhalation.

R. Rancourt, C. White, J. Loader, 2015, Toxicological sciences : an official journal of the Society of Toxicology.

Biological and molecular mechanisms of sulfur mustard analog-induced toxicity in JB6 and HaCaT cells: Possible role of ATM/ ATR-cell cycle checkpoint pathway

C. White, N. Tewari-Singh, C. Agarwal, 2011 .

Chlorine gas inhalation: human clinical evidence of toxicity and experience in animal models.

C. White, Carl W White, James G Martin, 2010, Proceedings of the American Thoracic Society.

Adenosine A2A receptor is a unique angiogenic target of HIF-2α in pulmonary endothelial cells

W. Franklin, Shama Ahmad, J. Schaack, 2009, Proceedings of the National Academy of Sciences.

Airway obstruction due to bronchial vascular injury after sulfur mustard analog inhalation.

R. Rancourt, C. White, J. Loader, 2010, American journal of respiratory and critical care medicine.

Differential regulation of pulmonary vascular cell growth by hypoxia-inducible transcription factor-1α and hypoxia-inducible transcription factor-2α.

K. Malcolm, Aftab Ahmad, Shama Ahmad, 2013, American journal of respiratory cell and molecular biology.

The lung response to ozone is determined by age and is partially dependent on toll-Like receptor 4

C. White, A. Dakhama, J. Loader, 2015, Respiratory Research.

Elevated expression of hexokinase II protects human lung epithelial-like A549 cells against oxidative injury.

Aftab Ahmad, Shama Ahmad, Ling-Yi L Chang, 2002, American journal of physiology. Lung cellular and molecular physiology.

Mice that overexpress Cu/Zn superoxide dismutase are resistant to allergen-induced changes in airway control.

A. Joetham, C. White, G. Larsen, 2000, American journal of physiology. Lung cellular and molecular physiology.

Effect of Preterm Birth on Hypoxia‐Inducible Factors and Vascular Endothelial Growth Factor in Primate Lungs

Aftab Ahmad, C. White, B. K. Schneider, 2005, Pediatric pulmonology.

Automated 3D segmentation of methyl isocyanate-exposed rat trachea using an ultra-thin, fully fiber optic optical coherence endoscopic probe

Matthew Brenner, Yusi Miao, Zhongping Chen, 2018, Scientific Reports.

Polyethylene glycol-attached antioxidant enzymes decrease pulmonary oxygen toxicity in rats.

J. Jackson, C. White, B. Freeman, 1989, Journal of applied physiology.

Thioredoxin Prevents Loss of UCP2 in Hyperoxia via MKK4-p38 MAPK- PGC1α Signaling and Limits Oxygen Toxicity.

C. White, Venkatesh Kundumani-Sridharan, K. Das, 2021, American journal of respiratory cell and molecular biology.

Development of a P2X1‐purinoceptor mediated contractile response in the aged mouse prostate gland through slowing down of ATP breakdown

C. White, R. Evans, J. Short, 2015, Neurourology and urodynamics.

NanoBRET: The Bright Future of Proximity-Based Assays

C. White, K. Pfleger, Natasha C. Dale, 2019, Front. Bioeng. Biotechnol..

Clinically-Relevant Cutaneous Lesions by Nitrogen Mustard: Useful Biomarkers of Vesicants Skin Injury in SKH-1 Hairless and C57BL/6 Mice

R. Agarwal, C. White, N. Tewari-Singh, 2013, PloS one.

A role for mitochondrial oxidative stress in sulfur mustard analog CEES-induced lung cell injury and antioxidant protection

C. White, B. Day, Neal S. Gould, 2008 .

Optimised insert design for improved single-molecule imaging and quantification through CRISPR-Cas9 mediated knock-in

Jeremy A Pike, Steven G Thomas, Natalie S Poulter, 2019, Scientific Reports.

Cigarette smoke extract increases S-adenosylmethionine and cystathionine in human lung epithelial-like (A549) cells.

C. White, M. Panayiotidis, R. Allen, 2004, Chemico-biological interactions.

Male contraception via simultaneous knockout of α1A-adrenoceptors and P2X1-purinoceptors in mice

C. White, R. Evans, A. Allen, 2013, Proceedings of the National Academy of Sciences.

CXCL17 is an endogenous inhibitor of CXCR4 via a novel mechanism of action

S. Hill, C. White, K. Pfleger, 2021, bioRxiv.

Failure of tumor necrosis factor and interleukin-1 to elicit superoxide production in the mitochondrial matrices of mammalian cells.

P. R. Gardner, C. White, 1996, Archives of biochemistry and biophysics.

Chlorine inhalation-induced myocardial depression and failure

S. Matalon, I. Zafar, Aftab Ahmad, 2015, Physiological reports.

Purinergic signaling and kinase activation for survival in pulmonary oxidative stress and disease.

Aftab Ahmad, Shama Ahmad, C. White, 2006, Free radical biology & medicine.

In vitro cell culture model for toxic inhaled chemical testing.

Shama Ahmad, C. White, K. Neeves, 2014, Journal of visualized experiments : JoVE.

Editor’s Highlight: Pulmonary Vascular Thrombosis in Rats Exposed to Inhaled Sulfur Mustard

R. Rancourt, C. White, J. Di Paola, 2017, Toxicological sciences : an official journal of the Society of Toxicology.

Sulfur mustard analog, 2-chloroethyl ethyl sulfide-induced skin injury involves DNA damage and induction of inflammatory mediators, in part via oxidative stress, in SKH-1 hairless mouse skin.

R. Agarwal, C. White, N. Tewari-Singh, 2011, Toxicology letters.

Interaction and localization of synthetic nanoparticles in healthy and cystic fibrosis airway epithelial cells: effect of ozone exposure.

B. Rothen‐Rutishauser, Shama Ahmad, C. White, 2012, Journal of aerosol medicine and pulmonary drug delivery.

O2-induced changes in lung and storage pool thiols in mice: effect of superoxide dismutase.

C. White, S. Stabler, L. Rusakow, 1993, Journal of applied physiology.

Identification and Profiling of Novel α1A-Adrenoceptor-CXC Chemokine Receptor 2 Heteromer

C. White, K. Pfleger, M. Ayoub, 2012, The Journal of Biological Chemistry.

The Residual Nonadrenergic Contractile Response to Nerve Stimulation of the Mouse Prostate Is Mediated by Acetylcholine but Not ATP in a Comparison with the Mouse Vas Deferens

C. White, R. Evans, J. Short, 2010, Journal of Pharmacology and Experimental Therapeutics.

Contractions of the Mouse Prostate Elicited by Acetylcholine Are Mediated by M3 Muscarinic Receptors

M. Matsui, C. White, J. Short, 2011, Journal of Pharmacology and Experimental Therapeutics.

The use of fluorescence correlation spectroscopy to monitor cell surface β2‐adrenoceptors at low expression levels in human embryonic stem cell‐derived cardiomyocytes and fibroblasts

S. Hill, C. White, S. Briddon, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

NanoBRET ligand binding at a GPCR under endogenous promotion facilitated by CRISPR/Cas9 genome editing.

C. White, K. Pfleger, H. B. See, 2019, Cellular signalling.

Blood sulfhydryl level increases during hyperoxia: a marker of oxidant lung injury.

C. White, J. Repine, S. K. Drake, 1989, Journal of applied physiology.

O2 metabolite-mediated injury in perfused kidneys is reflected by consumption of DMTU and glutathione.

C. White, S. Linas, J. Repine, 1987, The American journal of physiology.

Using nanoBRET and CRISPR/Cas9 to monitor proximity to a genome-edited protein in real-time

C. White, K. Pfleger, H. B. See, 2017, Scientific Reports.

NanoB2 to monitor interactions of ligands with membrane proteins by combining nanobodies and NanoBRET.

R. Bosma, M. Smit, M. Siderius, 2023, Cell reports methods.

A nanoluciferase biosensor to investigate endogenous chemokine secretion and receptor binding

S. Hill, C. White, K. Pfleger, 2020, bioRxiv.

Oxidative stress-induced regulation of the methionine metabolic pathway in human lung epithelial-like (A549) cells.

C. White, Aglaia Pappa, M. Panayiotidis, 2009, Mutation research.

Impact of SOD-Mimetic Manganoporphyrins on Spin Trapping of Superoxide and Related Artifacts

C. White, S. Eaton, B. Day, 2011, Applied magnetic resonance.

Effects of parenteral cysteine and glutathione feeding in a baboon model of severe prematurity.

C. White, R. Allen, S. Stabler, 2000, The American journal of clinical nutrition.

Complex Formation between VEGFR2 and the β2-Adrenoceptor

K. Wood, S. Hill, C. White, 2019, Cell chemical biology.

Dimethylthiourea decreases acute lung edema in phorbol myristate acetate-treated rabbits.

J. Jackson, C. White, J. Repine, 1986, Journal of applied physiology.

AMERICAN THORACIC SOCIETY DOCUMENTS

G. Redding, S. Matalon, R. Castile, 2017 .

Hyperoxia induces thioredoxin and thioredoxin reductase gene expression in lungs of premature baboons with respiratory distress and bronchopulmonary dysplasia.

C. White, X. Guo, K. Das, 1999, Chest.

Elevation of manganese superoxide dismutase gene expression by thioredoxin.

C. White, K. Das, Y. Lewis-Molock, 1997, American journal of respiratory cell and molecular biology.