C. K. Too

发表

Prolactin activates mammalian target-of-rapamycin through phosphatidylinositol 3-kinase and stimulates phosphorylation of p70S6K and 4E-binding protein-1 in lymphoma cells.

J. Bishop, Wei Lun Nien, S. Dauphinee, 2006, The Journal of endocrinology.

The Prostate 69 : 595 ^ 602 ( 2009 ) Overexpressionof 5 a-ReductaseType 1 Increases Sensitivityof ProstateCancerCells to Low Concentrations of Testosterone

C. K. Too, R. Rittmaster, L. Thomas, 2009 .

Levels of 5α-Reductase Type 1 and Type 2 are Increased in Localized High Grade Compared to Low Grade Prostate Cancer

C. K. Too, P. Murphy, R. Rittmaster, 2008 .

l -Arginine Uptake and Its Role in the Survival of Breast Cancer Cells

C. K. Too, S. Abdelmagid, 2017 .

Prolactin/Stat5 and androgen R1881 coactivate carboxypeptidase-D gene in breast cancer cells.

C. K. Too, L. Thomas, S. Koirala, 2014, Molecular endocrinology.

Prolactin and estrogen up-regulate carboxypeptidase-d to promote nitric oxide production and survival of mcf-7 breast cancer cells.

C. K. Too, S. Abdelmagid, 2008, Endocrinology.

Role of O‐linked β‐N‐acetylglucosamine modification in the subcellular distribution of alpha4 phosphoprotein and Sp1 in rat lymphoma cells

S. Dauphinee, C. K. Too, Marlene Ma, 2005, Journal of cellular biochemistry.

S100A10 Has a Critical Regulatory Function in Mammary Tumor Growth and Metastasis: Insights Using MMTV-PyMT Oncomice and Clinical Patient Sample Analysis

P. Marcato, D. Waisman, P. Marignani, 2020, Cancers.

Rapid induction of Jak2 and Sp1 in T cells by phosphorothioate oligonucleotides.

C. K. Too, 1998, Antisense & nucleic acid drug development.

Fibroblast growth factor-2 stimulates endothelial nitric oxide synthase expression and inhibits apoptosis by a nitric oxide-dependent pathway in Nb2 lymphoma cells.

C. K. Too, P. Murphy, M. Limoges, 2001, Endocrinology.

Fibroblast Growth Factor-2 Stimulates Endothelial Nitric Oxide Synthase Expression and Inhibits Apoptosis by a Nitric Oxide-Dependent Pathway in Nb2 Lymphoma Cells** This work was supported by Medical Research Council Grants MOP12597 (to P.R.M.) and MOP12895 (to C.K.L.T.).

C. K. Too, P. Murphy, M. Limoges, 2001, Endocrinology.

Prolactin induces expression of FGF-2 and a novel FGF-responsive NonO/p54nrb-related mRNA in rat lymphoma cells

C. K. Too, P. Murphy, R. Knee, 1998, Molecular and Cellular Endocrinology.

FGF-2 antisense RNA encodes a nuclear protein with MutT-like antimutator activity

C. K. Too, P. Murphy, M. Wilkinson, 1997, Molecular and Cellular Endocrinology.

Identification of amiloride-sensitive Na+/H+ exchange in rat NB2 node lymphoma cells. Stimulation by 12-O-tetradecanoyl-phorbol-13-acetate.

C. K. Too, P. Murphy, H. Friesen, 1987, Endocrinology.

A novel mutation in Exon 4 of the low density lipoprotein receptor gene resulting in heterozygous familial hypercholesterolemia associated with decreased ligand binding.

D. Guernsey, C. K. Too, M. Tan, 1998, Atherosclerosis.

S100A10 Has a Critical Regulatory Function in Mammary Tumor Growth and Metastasis: Insights Using MMTV-PyMT Oncomice and Clinical Patient Sample Analysis

P. Marcato, D. Waisman, P. Marignani, 2020, Cancers.

Testosterone and prolactin increase carboxypeptidase‐D and nitric oxide levels to promote survival of prostate cancer cells

C. K. Too, L. Thomas, Timothy J Morehouse, 2012, The Prostate.

Levels of 5alpha-reductase type 1 and type 2 are increased in localized high grade compared to low grade prostate cancer.

C. K. Too, P. Murphy, R. Rittmaster, 2008, The Journal of urology.

Differential expression of elongation factor-2, α4 phosphoprotein and Cdc5-like protein in prolactin-dependent/independent rat lymphoid cells

C. K. Too, 1997, Molecular and Cellular Endocrinology.

Estrogen stimulates expression of adenine nucleotide translocator ANT1 messenger RNA in female rat hearts

C. K. Too, M. Wilkinson, Alice Giles, 1999, Molecular and Cellular Endocrinology.

CAT‐1‐mediated arginine uptake and regulation of nitric oxide synthases for the survival of human breast cancer cell lines

C. K. Too, S. Abdelmagid, J. Rickard, 2011, Journal of cellular biochemistry.

Design, synthesis and bioevaluation of novel candidate selective estrogen receptor modulators.

V. S. Parmar, A. Jha, C. K. Too, 2011, European journal of medicinal chemistry.

G-proteins modulate prolactin- and interleukin-2-stimulated mitogenesis in rat Nb2 lymphoma cells.

C. K. Too, P. Murphy, H. Friesen, 1989, Endocrinology.

Prolactin‐ and testosterone‐induced carboxypeptidase‐D correlates with increased nitrotyrosines and Ki67 in prostate cancer

C. K. Too, J. Merrimen, R. Rendon, 2015, The Prostate.

Amiloride-sensitive Na+/H+ exchange in rat NB2 node lymphoma cells. Stimulation by prolactin and other mitogens.

C. K. Too, H. Friesen, E. Cragoe, 1987, Endocrinology.

p11 cell density, and

Thomas, P. Marcato, D. Waisman, 2020 .

L‐arginine inhibits apoptosis via a NO‐dependent mechanism in Nb2 lymphoma cells

C. K. Too, P. Murphy, Robert T. M. Boudreau, 2000, Journal of cellular biochemistry.

The role of G-proteins in the mitogenesis of rat lactogen-dependent and lactogen-independent Nb2 lymphoma cells.

C. K. Too, P. Murphy, H. Friesen, 1990, Endocrinology.

Carboxypeptidase‐D is elevated in prostate cancer and its anti‐apoptotic activity is abolished by combined androgen and prolactin receptor targeting

C. K. Too, V. Goffin, J. Merrimen, 2014, The Prostate.

Carboxypeptidase-DisElevatedinProstateCancerandits Anti-ApoptoticActivityisAbolishedbyCombined AndrogenandProlactinReceptorTargeting

C. K. Too, V. Goffin, J. Merrimen, 2014 .

Type 1 and Type 2 5α-Reductase Expression in the Development and Progression of Prostate Cancer

D. Tindall, C. K. Too, R. Rittmaster, 2008 .

Relaxin increases the release of plasminogen activator, collagenase, and proteoglycanase from rat granulosa cells in vitro.

C. K. Too, F. Greenwood, C K Too, 1984, Endocrinology.

Passage of X-ray-induced immortal, non-transformed phenotype by DNA-mediated transfection.

L. Oberley, D. Guernsey, C. K. Too, 1995, Cancer letters.

Malignant progression of rat Nb2 lymphoma cells: chromosomal alterations and metastatic properties.

C. K. Too, P. Gout, C. Lee, 1999, Cancer genetics and cytogenetics.

Distribution of serotonin in the sea scallop Placopecten magellanicus

R. Croll, C. K. Too, J. Nason, 1995 .

Detection of FMRFamide-like immunoreactivities in the sea scallopPlacopecten magellanicus by immunohistochemistry and Western blot analysis

R. Croll, C. K. Too, 1995, Cell and Tissue Research.

Coexpression and regulation of the FGF-2 and FGF antisense genes in leukemic cells.

A. Casson, C. K. Too, P. Murphy, 2005, Leukemia research.

Induction of Sp1 activity by prolactin and interleukin-2 in Nb2 T-cells: differential association of Sp1–DNA complexes with Stats

C. K. Too, 1997, Molecular and Cellular Endocrinology.

Design, synthesis and bioevaluation of novel 6-(4-Hydroxypiperidino)naphthalen-2-ol-based potential Selective Estrogen Receptor Modulators for breast cancer.

A. Jha, C. K. Too, J. Balzarini, 2015, European journal of medicinal chemistry.

Prolactin and androgen R1881 induce pro-survival carboxypeptidase-D and EDD E3 ligase in triple-negative and HER2+ breast cancer.

C. K. Too, Tyler M MacDonald, L. Thomas, 2020, American journal of cancer research.

Prolactin, interleukin-2 and FGF-2 stimulate expression, nuclear distribution and DNA-binding of rat homolog of pombe Cdc5 in Nb2 T lymphoma cells

C. K. Too, L. M. Johnson, 2001, Molecular and Cellular Endocrinology.

Cross-linking of G-proteins to the prolactin receptor in rat NB2 lymphoma cells.

C. K. Too, H. Friesen, R. Shiu, 1990, Biochemical and biophysical research communications.

Deletion of N-terminal amino acids from human lecithin:cholesterol acyltransferase differentially affects enzyme activity toward alpha- and beta-substrate lipoproteins.

R. McLeod, C. K. Too, N. Vickaryous, 2003, Biochimica et biophysica acta.

Implication of (cid:1) 4 phosphoprotein and the rapamycin-sensitive mammalian target-of-rapamycin pathway in prolactin receptor signalling

S. Dauphinee, C. K. Too, A. Li, 2002 .

Prolactin/androgen-inducible carboxypeptidase-D increases with nitrotyrosine and Ki67 for breast cancer progression in vivo, and upregulates progression markers VEGF-C and Runx2 in vitro

C. K. Too, L. Thomas, Penelope J Barnes, 2017, Breast Cancer Research and Treatment.

Identification and nuclear localization of a novel prolactin and cytokine-responsive carboxypeptidase D.

C. K. Too, N. Vickaryous, R. Boudreau, 2001, Endocrinology.

Characterization of 123I-iodo-α-methyltyrosine transport in rat lymphoma cells

C. K. Too, G. Matte, M. Acker, 2005 .

The basic fibroblast growth factor (FGF-2) antisense RNA (GFG) is translated into a MutT-related protein in vivo.

C. K. Too, P. Murphy, A. Li, 1996, Biochemical and biophysical research communications.

Prolactin-inducible EDD E3 ubiquitin ligase promotes TORC1 signalling, anti-apoptotic protein expression, and drug resistance in breast cancer cells.

P. Marignani, C. K. Too, Tyler M MacDonald, 2019, American journal of cancer research.

Relaxin stimulates collagenase and plasminogen activator secretion by dispersed human amnion and chorion cells in vitro.

C. K. Too, F. Greenwood, E. Koay, 1983, The Journal of clinical endocrinology and metabolism.

The effect of oestrogen and relaxin on uterine and cervical enzymes: collagenase, proteoglycanase and beta-glycuronidase.

C. K. Too, F. Greenwood, G. Bryant-Greenwood, 1986, Acta endocrinologica.

Further purification of human pituitary-derived chondrocyte growth factor: heparin-binding and cross-reactivity with antiserum to basic FGF.

C. K. Too, P. Murphy, H. Friesen, 1987, Biochemical and biophysical research communications.

Type 1 and type 2 5alpha-reductase expression in the development and progression of prostate cancer.

D. Tindall, C. K. Too, R. Rittmaster, 2008, European urology.

Relaxin stimulates plasminogen activator secretion by rat granulosa cells in vitro.

C. K. Too, T. Weiss, G. Bryant-Greenwood, 1982, Endocrinology.

Phloridzin docosahexaenoate, a novel flavonoid derivative, suppresses growth and induces apoptosis in T-cell acute lymphoblastic leukemia cells.

H. Rupasinghe, J. Berman, C. K. Too, 2017, American journal of cancer research.

α4 phosphoprotein interacts with EDD E3 ubiquitin ligase and poly(A)‐binding protein

C. K. Too, M. Henderson, Lori D. Moffat, 2010, Journal of cellular biochemistry.

Western blotting of formaldehyde-fixed neuropeptides as small as 400 daltons on gelatin-coated nitrocellulose paper.

R. Croll, C. K. Too, P. Murphy, 1994, Analytical biochemistry.

Overexpression of the mTOR alpha4 phosphoprotein activates protein phosphatase 2A and increases Stat1α binding to PIAS1

Wei Lun Nien, S. Dauphinee, C. K. Too, 2007, Molecular and Cellular Endocrinology.

Progestin-inducible EDD E3 ubiquitin ligase binds to α4 phosphoprotein to regulate ubiquitination and degradation of protein phosphatase PP2Ac

C. K. Too, L. Thomas, S. Koirala, 2014, Molecular and Cellular Endocrinology.

In-gel ligand blotting with 125I-heparin for detection of heparin-binding growth factors.

C. K. Too, P. Murphy, H. Friesen, 1990, Analytical biochemistry.

Characterization of a novel, cytokine-inducible carboxypeptidase D isoform in haematopoietic tumour cells.

C. K. Too, S. Bearne, S. Abdelmagid, 2005, The Biochemical journal.

Increased messenger RNA levels of the antagonist thyroid hormone receptor erbA-alpha 2 and decreased levels of erbA-alpha 1 and erbA-beta 1 receptor messenger RNAs in neoplastic rodent cells.

D. Guernsey, C. K. Too, 1992, Cancer research.

Elevation of the thyroid hormone receptor erb A-alpha 2 mRNA in transformed rodent cells is due to increased message stability.

D. Guernsey, C. K. Too, 1993, Cancer letters.